Search results for ""taylor francis inc""

Emerging Communication Technologies Based on Wireless Sensor Networks: Current Research and Future Applications fills a gap in the existing literature by combining a plethora of WSN-based emerging technologies into a single source so that researchers can form opinions regarding these technologies. It presents different types of emerging communication technologies based on WSNs and describes how wireless sensor networks can be integrated with other communication technologies. It covers many of the new techniques and demonstrates the application of WSNs. The book’s 14 chapters are divided into four parts.The first part covers the basics of wireless sensor networks and their principal working methods. The authors then move on to discuss different types of WSNs, characteristics of different types of emerging technologies based on WSNs, renewable energy sources, battery replenishment strategies, and application-specific energy challenges of WSNs. The second part is dedicated to issues related to wireless body area networks (WBANs). It discusses wearable WSNs and their applications, standards, and research trends. The authors also discuss routing schemes devised for WBANs and thermal-aware routing protocols for WBANs.The third part focuses on different emerging communication technologies based on WSNs, including electromagnetic wireless nanosensor networks, WSNs in the IoT, management of WSNs through satellite networks, WSNs in smart homes, and cognitive radio technology in conjunction with WSNs. The last part of the book covers topics generally related to typical WSNs, including energy-efficient data collection in WSNs, key distribution mechanisms in WSNs, distributed data gathering algorithms for mobile WSNs, and finally, a novel mobility scheme for WSNs that supports IPv6.

Read more less

Explore a Viable Resource for DesalinationThe world’s freshwater supplies are rapidly depleting and seawater is being positioned as a major feasible replacement in the search for a sustainable water source. Focused on large-scale multi-stage flash (MSF) seawater desalination plants, and based on research conducted on a real 18-stage plant, Multi-Stage Flash Desalination: Modeling, Simulation and Adaptive Control outlines the principles and processes of MSF desalination and highlights the state of the art in MSF desalination modeling, simulation, and control. This book offers a brief overview of MSF plants, explains the importance of the various control systems for large MSF plants, and describes methods of mathematical modeling centered on physical phenomena in the MSF process. It introduces a developed dynamic model and illustrates the simulation of the model using an equation-based flowsheet simulation package (SPEEDUP) from AspenTech. It also presents a method for finding and using a non-parametric model in designing optimal PID control systems and recommends an adaptive scheme that maintains optimal plant operation over a range of operating conditions. The improvements suggested by the author for PID controllers are pervasive in desalination plants of high dimension and also relate to other process industries with comparable conditions. He also discusses the use of renewable energy sources for desalination and stresses the potential of solar energy in the Arab region, an area known for its aridity and scarcity of water.The text: Details the dynamic model of the various elements in an MSF plant Considers the obtained model as well as available measurement data Presents a developed model for use in PID control Provides descriptions, listings, and additional reference material for further research Multi-Stage Flash Desalination: Modeling, Simulation and Adaptive Control covers the processes of desalination and the operation and control of MSF plants for large-scale desalination and provides you with a greater understanding of dynamics, operation, and control.

Read more less

While nutraceuticals were verified to be expedient, they often lack stability, bioavailability, and permeability, and nano-nutraceuticals are being developed to afford a solution to the problem. Nanotechnology in Nutraceuticals: Production to Consumption delves into the promises and prospects of the application of nanotechnology to nutraceuticals, addressing concepts, techniques, and production methods. Nutraceuticals retain less stability, efficacy, and bioavailability when entering the human body. To overcome such problems, nanotechnology shows promise when applied as a tool to improve the quality and stability of nutraceuticals. This book discusses metallic nanoparticles and their applications in the food industry with specific application to nutraceuticals. It includes detailed discussion on potential functional properties of nutraceuticals with regard to antimicrobial activity, anti-inflammatory activity, and anti-cancer activity. Since nanoparticles can be toxic past a certain limit, implementing nanotechnology under thoughtful regulations is considered critical. The book addresses these issues with chapters covering the principles for the oversight of nanotechnologies and nanomaterials in nutraceuticals, the implications of regulatory requirements, the ethics and economics of nano-nutraceuticals, and consumer acceptance of nanotechnology based foods.

Read more less

Computational Aspects of Polynomial Identities: Volume l, Kemer’s Theorems, 2nd Edition presents the underlying ideas in recent polynomial identity (PI)-theory and demonstrates the validity of the proofs of PI-theorems. This edition gives all the details involved in Kemer’s proof of Specht’s conjecture for affine PI-algebras in characteristic 0.The book first discusses the theory needed for Kemer’s proof, including the featured role of Grassmann algebra and the translation to superalgebras. The authors develop Kemer polynomials for arbitrary varieties as tools for proving diverse theorems. They also lay the groundwork for analogous theorems that have recently been proved for Lie algebras and alternative algebras. They then describe counterexamples to Specht’s conjecture in characteristic p as well as the underlying theory. The book also covers Noetherian PI-algebras, Poincaré–Hilbert series, Gelfand–Kirillov dimension, the combinatoric theory of affine PI-algebras, and homogeneous identities in terms of the representation theory of the general linear group GL.Through the theory of Kemer polynomials, this edition shows that the techniques of finite dimensional algebras are available for all affine PI-algebras. It also emphasizes the Grassmann algebra as a recurring theme, including in Rosset’s proof of the Amitsur–Levitzki theorem, a simple example of a finitely based T-ideal, the link between algebras and superalgebras, and a test algebra for counterexamples in characteristic p.

Read more less

Smart Grid: Networking, Data Management, and Business Models delivers a comprehensive overview of smart grid communications, discussing the latest advances in the technology, the related cyber security issues, and the best ways to manage user demand and pricing. Comprised of 16 chapters authored by world-renowned experts, this book: Considers the use of cognitive radio and software-defined networking in the smart grid Explores the space of attacks in the energy management process, the need for a smart grid simulator, and the management issues that arise around smart cities Describes a real-time pricing scheme that aims to reduce the peak-to-average load ratio Explains how to realize low-carbon economies and the green smart grid through the pervasive management of demand Presents cutting-edge research on microgrids, electric vehicles, and energy trading in the smart grid Thus, Smart Grid: Networking, Data Management, and Business Models provides a valuable reference for utility operators, telecom operators, communications engineers, power engineers, electric vehicle original equipment manufacturers (OEMs), electric vehicle service providers, university professors, researchers, and students.

Read more less

This book explores the challenges of presenting sustainability as a more actionable or practical concept and identifying approaches that might offer useful assistance in addressing the temporal and spatial representation of sustainability. The underlying premise of this book is that sustainability is a state realized in the future. In that future there is a geographic arrangement of society and economy that agrees with its environmental setting. This future perspective introduces a little examined subject area that can lend significant content to the sustainability challenge: Futures Research.

Read more less

Textiles and Human Thermophysiological Comfort in the Indoor Environment delivers a methodical assessment of textile structures for various applications in the indoor environment with respect to the thermophysiological comfort of the inhabitants. The book begins by offering an overview of the role of indoor textiles and clothing as a barrier between the environment and the human body, and then: Explores the use of textiles as an insulation barrier, examining the relationships between textiles and the environment, and textiles and the human body Details an experimental study of heat and mass transfer processes through woven textiles with different applications in the indoor environment Describes a numerical investigation of the transport of air and heat through woven fabrics by means of computational fluid dynamics (CFD) Develops, applies, and verifies an original approach for simulating the woven macrostructure as a jet system, presenting proven results Evaluates thermophysiological comfort under the influence of indoor environmental parameters, clothing insulation, and activity Textiles and Human Thermophysiological Comfort in the Indoor Environment provides a valuable reference for students and researchers working in the area of clothing comfort.

Read more less

The CRC Handbook of Thermal Engineering, Second Edition, is a fully updated version of this respected reference work, with chapters written by leading experts. Its first part covers basic concepts, equations and principles of thermodynamics, heat transfer, and fluid dynamics. Following that is detailed coverage of major application areas, such as bioengineering, energy-efficient building systems, traditional and renewable energy sources, food processing, and aerospace heat transfer topics. The latest numerical and computational tools, microscale and nanoscale engineering, and new complex-structured materials are also presented. Designed for easy reference, this new edition is a must-have volume for engineers and researchers around the globe.

Read more less

"Alvarez drives home the point that for buildings and communities located in hurricane-prone regions, it is not a question of whether the area will be impacted, but when it will be impacted. The book makes a strong case for taking responsibility to understand the vulnerabilities of buildings and structures to hurricane impacts."—Timothy Reinhold, PhD, from the ForewordFocusing on coastal regions affected by tropical cyclones, Hurricane Mitigation for the Built Environment highlights vulnerability, natural hazards, risk, damage, emergency management, and hazard mitigation as they relate to the threat and occurrence of hurricanes. The product of more than 25 years of the author’s experiences with post-event assessments and studies of hurricane damage, it looks particularly at common sequences of failures and oversights in planning for a hurricane that amplify the damage caused by storms.This book combines observations of actual damage to the built environment in coastal regions caused by hurricanes with applied research and testing. It uses case studies and imagery from recent storms to show some of the strengths and weaknesses of infrastructure, landscaping, and city planning. The case studies also illustrate, in great detail, what community planning efforts have worked and those that have failed.The book also goes beyond analyzing immediately visible structural damages following a hurricane. It addresses long-term issues such as beach erosion and struggling tourism economies. It also describes specific, realistic, and essential mitigation measures for reducing the damage potential of future hurricanes and urges developers, designers, and owners to incorporate new knowledge into the design of new buildings or into the retrofitting of existing buildings. By applying the information presented in this book, communities susceptible to recurring hurricanes can reduce storm damage as well as the potential for extended losses that frequently follow a hurricane.

Read more less

Natural foods, like fruits and vegetables, represent the simplest form of functional foods and provide excellent sources of functional compounds. Maximizing opportunities to make use of and incorporate these compounds requires special processing. Fortunately, technologies available to produce food with enhanced active compounds have advanced significantly over the last few years. This book covers the fundamentals as well as the innovations made during the last few years on the emerging technologies used in the development of food with bioactive compounds.

Read more less

Hyperthermia in oncology is the application of heat to a patient’s body for the purpose of cancer treatment. In recent years, its use has seen rapid development, with a large amount of clinical data becoming available. Hyperthermia in Oncology synthesizes the current research on the topic and provides treatment protocols for using localized as well as whole-body hyperthermia. The differentiating characteristic of this book is the systematic documentation of evidence. Standard procedures for cancer diagnosis, treatment, and management are included along with guidance for evaluating clinical therapeutic effects. The book examines the unique effects of hyperthermia treatment with a large quantity of evidence-based data from both medical research and clinical practice. It reviews outcomes of cancer patients clinically treated at Clifford Hospital, a state-of-the-art facility with Joint Commission International accreditation located in Guangzhou, China. A diverse set of clinical cases is discussed. For each case, a scientific, rational, and practical patient treatment plan is presented. The amount and type of heat administered to patients are analyzed when hyperthermia is used in conjunction with surgery, chemotherapy, radiotherapy, or other therapeutic strategies.Although hyperthermia is not an independent treatment method for cancer, it can play a significant synergistic and complementary role. As such, this book can serve as a valuable clinical guide for the effective use of hyperthermia in integrative cancer therapy.

Read more less

The Handbook of Discrete and Computational Geometry is intended as a reference book fully accessible to nonspecialists as well as specialists, covering all major aspects of both fields. The book offers the most important results and methods in discrete and computational geometry to those who use them in their work, both in the academic world—as researchers in mathematics and computer science—and in the professional world—as practitioners in fields as diverse as operations research, molecular biology, and robotics. Discrete geometry has contributed significantly to the growth of discrete mathematics in recent years. This has been fueled partly by the advent of powerful computers and by the recent explosion of activity in the relatively young field of computational geometry. This synthesis between discrete and computational geometry lies at the heart of this Handbook. A growing list of application fields includes combinatorial optimization, computer-aided design, computer graphics, crystallography, data analysis, error-correcting codes, geographic information systems, motion planning, operations research, pattern recognition, robotics, solid modeling, and tomography.

Read more less

The fourth edition of this text constitutes a continuation of 20 years of coverage of traumatic brain injury, and broadens the discussion of acquired brain injury. Within TBI, the paradigm shift from an injury occurring at a point in time to a disease entity of a chronic nature is changing the discussion of diagnosis, management, treatment and outcome assessment. Disease specification that differentiates TBIs by the mechanism of injury, the exact nature of the injury, the extent of injury, presence of co-morbidities and their exact nature, gender, age, race, and genome are emerging as crucial. Disease differentiation has impacted diagnosis, treatment and outcome.

Read more less

Supply chain management decisions are made under the conflicting criteria of maximizing profit and customer responsiveness while minimizing supply chain risk. Multiple Criteria Decision Making in Supply Chain Management provides a comprehensive overview of multi-criteria optimization models and methods that can be used in supply chain decision making.Presenting the contributions of internationally known authors, researchers, educators, and practitioners, this new book in the Operations Research Series provides readers with a single source guide to recent developments in this area. The focus of the book is on the design and operation of the supply chain system, which involves connecting many production and distribution systems, often across wide geographic distances, in such a way that the businesses involved can ultimately satisfy the consumer demand as efficiently as possible, resulting in maximum financial returns to those businesses connected to that supply chain system. The book includes several case studies on the design and operation of supply chain networks in manufacturing and healthcare.

Read more less

The book Arthropod-borne Infectious Diseases of the Dog and Cat is edited by professor Michael Day – a living legend of veterinary science in the fields of immunology and clinical pathology. All veterinary practitioners in Europe should be familiar with this issue, even though they have never seen some of those diseases. For that reason Arthropod-borne Infectious Diseases of the Dog and Cat is a must-have book for a practitioner’s professional library. -- Nenad Milojković, DVM (Serbia), in FECAVA, June 2019 Arthropod-borne Infectious Diseases of the Dog and Cat is an invaluable resource for information on the clinical presentation, pathogenesis, diagnosis and treatment of the major arthropod-borne diseases of dogs and cats. Also discussed is an array of diagnostic techniques routinely available to veterinarians presented with these diseases. Illustrated in colour throughout, the book incorporates photographs of clinical cases, haematology, cytology and gross and microscopic pathology, which help understand the diagnosis and treatment of these diseases. While its fundamental structure remains unchanged, this new edition adds a chapter on haemoplasma infections as well as a revised chapter on rare, and particularly viral, arthropod-borne diseases of dogs and cats. This new edition is fully updated to reflect the changes and geographical spread of the diseases covered. New for this edition is the inclusion of a series of clinical case studies providing relevant examples of the diseases discussed. In short, the book provides an accessible guide to arthropod-borne infectious disease for veterinarians both in practice and training. With the effects of climate change and increasing international pet travel, this book is a useful addition to every small animal practitioner's library.

Read more less

This dedicated overview of optical compressive imaging addresses implementation aspects of the revolutionary theory of compressive sensing (CS) in the field of optical imaging and sensing. It overviews the technological opportunities and challenges involved in optical design and implementation, from basic theory to optical architectures and systems for compressive imaging in various spectral regimes, spectral and hyperspectral imaging, polarimetric sensing, three-dimensional imaging, super-resolution imaging, lens-free, on-chip microscopy, and phase sensing and retrieval. The reader will gain a complete introduction to theory, experiment, and practical use for reducing hardware, shortening image scanning time, and improving image resolution as well as other performance parameters. Optics practitioners and optical system designers, electrical and optical engineers, mathematicians, and signal processing professionals will all find the book a unique trove of information and practical guidance.

Read more less

Directional antenna technologies have made significant advancements in the last decade. These advances have opened the door to many exciting new design opportunities for wireless networks to enhance quality of service (QoS), performance, and network capacity. In this book, experts from around the world present the latest research and development in wireless networks with directional antennas. Their contributed chapters provide detailed coverage of the models, algorithms, protocols, and applications of wireless networks with various types of directional antennas operating at different frequency bands.Wireless Network Performance Enhancement via Directional Antennas: Models, Protocols, and Systems identifies several interesting research problems in this important field, providing an opportunity to learn about solid solutions to these issues. It also looks at a number of practical hardware designs for the deployment of next-generation antennas, as well as efficient network protocols for exploitation of directional communications. The book is organized into six sections: Directional Antennas – covers the hardware design of different types of antennas Directional MAC – focuses on the principles of designing medium access control (MAC) protocols for directional networks Millimeter Wave – explores different design aspects of millimeter wave (mm-Wave) systems, which operate in higher-frequency bands (such as 60 GHz) MIMO – explains how to establish a multiple-input, multiple-output (MIMO) antenna system and describes how it operates in a cognitive radio network Advanced Topics – looks at additional topics such as beamforming in cognitive radio networks, multicast algorithm development, network topology management for connectivity, and sensor network lifetime issues Applications – illustrates some important applications, such as military networks and airborne networking, that benefit from directional networking designs With this book, researchers and engineers will be well-equipped to advance the research and development in this important field. If you’re new to this field, you will find this book to be a valuable reference on basic directional networking principles, engineering design, and challenges.

Read more less

The emergence of nanotherapeutics is attributable to the integration of nanotechnology, recombinant DNA technology, and synthetic organic chemistry with medicine for treating critical human diseases in a more efficient and specific molecular approach than therapy with conventionally-designed and formulated drugs. Nanotherapeutics: From Laboratory to Clinic comprehensively discusses the current shortcomings for delivery of classical (small) drugs, macromolecular therapeutics, and recombinant vaccine via the common intravascular and extravascular routes.The book describes the synthetic/chemical engineering methods as well as recombinant, hybridoma, and phage display technologies to fabricate different types of nanoparticulate carriers and drugs. It also reveals the diversified approaches undertaken by harnessing nanotechnology to overcome the multistep extracellular and intracellular barriers and to facilitate the development of novel strategies for therapeutic delivery and imaging. The author elaborates on the preclinical and clinical trials of potential nanoparticle-based products in animal models and patients and the approval/commercialization of nanotherapeutics, addressing all relevant human diseases.A focus on the above issues in a concise but illustrative manner fills the gap between the laboratory findings originating from the research on identification of cellular and systemic barriers of classical and macromolecular drugs along with development of strategies for fabrication and testing of nanotherapeutics, and the clinical outcomes emanating from the testing of the selected potential nanotherapeutics on patients of particular diseases. The book also fills a gap in the existing literature between the design and development of diversified nanotherapeutics for various purposes and the investigation and evaluation of potential barriers and resultant therapeutic efficacy of those nano-medicine formulations.

Read more less

This book explores the methods needed for creating and manipulating HDR content. HDR is a step change from traditional imaging; more closely matching what we see with our eyes. In the years since the first edition of this book appeared, HDR has become much more widespread, moving from a research concept to a standard imaging method. This new edition incorporates all the many developments in HDR since the first edition and once again emphasizes practical tips, including the authors' popular HDR Toolbox (available on the authors' website) for MATLAB and gives readers the tools they need to develop and experiment with new techniques for creating compelling HDR content.Key Features: Contains the HDR Toolbox for readers' experimentation on authors' website Offers an up-to-date, detailed guide to the theory and practice of high dynamic range imaging Covers all aspects of the field, from capture to display Provides benchmarks for evaluating HDR imagery

Read more less

A decade ago, UK HealthCare recognized the need to reposition itself as a regional referral center, focusing on advanced subspecialty care for the entire state of Kentucky. The goal was to become a "medical destination" for patients from that region who needed access to specialized care.To support that goal, UK HealthCare established a virtual network of partnering provider organizations throughout Kentucky. By working together, UK HealthCare and its partners provide all Kentuckians access to the appropriate levels of care as close to home as possible.Clinical Co-Management: A Bridge to Clinical Integration and Pathway to Bundled Payments supplies a detailed view of the Clinical Co-Management Agreement (CCMA) framework. It describes how the successful implementation of CCMAs can pave the way to coordinated efforts by hospital administration and physicians to reduce cost, increase quality, and improve patient satisfaction.Detailing why CCMAs present a viable alternative to conventional hospital-physician alignment models, such as medical directorships, committee chairs, and physician employment, the book presents an insider's view of the working models for clinical co-management programs.Complete with a detailed explanation of the self-referral statute (Stark Law) and the Anti-Kickback Statute, this book provides physicians, hospital executives, healthcare attorneys, and industry experts with a trustworthy reference they can refer to prior to and during CCMA negotiations, implementation, and oversight.Includes a Foreword by Mark D. Birdwhistell, Vice-President for Administration and External Affairs, UK HealthCare

Read more less

Surgical oncology is now a recognized specialty in the US and several European countries, and cancer surgery takes up a significant part of any general surgeon’s workload. This thoroughly updated second edition of this bestseller is officially endorsed as a textbook for the syllabus and curriculum of the UEMS examination in Surgical Oncology, which is administered by ESSO (European Society for Surgical Oncology). The examination is for trainees at the end of training or established consultants seeking to expand their accreditation.

Read more less

Direct Pay: A Simpler Way to Practice Medicine examines the direct pay business model as a policy alternative and potential policy solution to the economic, technological, and sociocultural problems that have emerged for practicing physicians as a result of the Affordable Care Act. Based on a research study conducted by the author, the book addresses key research issues that are supported by theory and recent literature.The research and hypotheses presented in the text are tested and proven through a set of questionnaires, interviews with direct pay physicians, and case studies that illustrate how the subject originated and why it is gaining momentum in today’s challenging health reform environment.The book provides guidance on direct pay from a public policy perspective. It examines the impact of recent health reform policies and provisions on direct pay physicians, including the individual mandate and universal coverage provisions, patient-centered medical home (PCMH) certification and model of care, provisions to expand Medicaid and changes to reimbursement for Medicare, policy changes from HIPAA, and the HIT policy of Meaningful Use (MU).The book analyzes the organizational style and culture of the participating direct pay practices using theoretical and practical tests of the Competing Values Framework. It not only gauges the practices and policy implementation of direct pay practices, but also searches for variations between pure versus hybrid organizational identity of direct pay practices, and variations between direct pay practices operating on all-inclusive, fee-for-care (FFC) models versus fee-for-service (FFS) payment models.Providing a fundamental understanding of direct pay, the book highlights emerging trends and supplies authoritative analysis on how the direct pay business model can help to advance the practice of medicine through improved efficiency and effectiveness.

Read more less

Elaborating on the concept of context awareness, this book presents up-to-date research and novel framework designs for context-aware mobile sensing. Generic and Energy-Efficient Context-Aware Mobile Sensing proposes novel context-inferring algorithms and generic framework designs that can help readers enhance existing tradeoffs in mobile sensing, especially between accuracy and power consumption.The book presents solutions that emphasize must-have system characteristics such as energy efficiency, accuracy, robustness, adaptability, time-invariance, and optimal sensor sensing. Numerous application examples guide readers from fundamental concepts to the implementation of context-aware-related algorithms and frameworks.Covering theory and practical strategies for context awareness in mobile sensing, the book will help readers develop the modeling and analysis skills required to build futuristic context-aware framework designs for resource-constrained platforms. Includes best practices for designing and implementing practical context-aware frameworks in ubiquitous/mobile sensing Proposes a lightweight online classification method to detect user-centric postural actions Examines mobile device-based battery modeling under the scope of battery nonlinearities with respect to variant loads Unveils a novel discrete time inhomogeneous hidden semi-Markov model (DT-IHS-MM)-based generic framework to achieve a better realization of HAR-based mobile context awareness Supplying theory and equation derivations for all the concepts discussed, the book includes design tips for the implementation of smartphone programming as well as pointers on how to make the best use of MATLAB® for the presentation of performance analysis. Coverage includes lightweight, online, and unsupervised pattern recognition methods; adaptive, time-variant, and optimal sensory sampling strategies; and energy-efficient, robust, and inhomogeneous context-aware framework designs.Researchers will learn the latest modeling and analysis research on mobile sensing. Students will gain access to accessible reference material on mobile sensing theory and practice. Engineers will gain authoritative insights into cutting-edge system designs.

Read more less

How Can We Lower the Power Consumption of Gas Sensors?There is a growing demand for low-power, high-density gas sensor arrays that can overcome problems relative to high power consumption. Low power consumption is a prerequisite for any type of sensor system to operate at optimum efficiency. Focused on fabrication-friendly microelectromechanical systems (MEMS) and other areas of sensor technology, MEMS and Nanotechnology for Gas Sensors explores the distinct advantages of using MEMS in low power consumption, and provides extensive coverage of the MEMS/nanotechnology platform for gas sensor applications.This book outlines the microfabrication technology needed to fabricate a gas sensor on a MEMS platform. It discusses semiconductors, graphene, nanocrystalline ZnO-based microfabricated sensors, and nanostructures for volatile organic compounds. It also includes performance parameters for the state of the art of sensors, and the applications of MEMS and nanotechnology in different areas relevant to the sensor domain.In addition, the book includes: An introduction to MEMS for MEMS materials, and a historical background of MEMS A concept for cleanroom technology The substrate materials used for MEMS Two types of deposition techniques, including chemical vapour deposition (CVD) The properties and types of photoresists, and the photolithographic processes Different micromachining techniques for the gas sensor platform, and bulk and surface micromachining The design issues of a microheater for MEMS-based sensors The synthesis technique of a nanocrystalline metal oxide layer A detailed review about graphene; its different deposition techniques; and its important electronic, electrical, and mechanical properties with its application as a gas sensor Low-cost, low-temperature synthesis techniques An explanation of volatile organic compound (VOC) detection and how relative humidity affects the sensing parameters MEMS and Nanotechnology for Gas Sensors provides a broad overview of current, emerging, and possible future MEMS applications. MEMS technology can be applied in the automotive, consumer, industrial, and biotechnology domains.

Read more less

The prevalence of Oral and Oropharyngeal Cancer continues to rise worldwide, related to the increase in consumption of tobacco, alcohol and other carcinogenic products. However, there has also been a significant reduction in mortality due to increasing awareness, early diagnosis and advances in treatments. This second edition of a bestseller reviews every aspect of the diagnosis and treatment of the orofacial cancer patient. As with the first edition, the book is organized in three parts, covering Pathology and Biology, Clinical Management, and Outcomes and Follow-up.

Read more less

The nutritional benefits of marine flora and fauna are well known. Fish and crustaceans provide high-quality sources of amino acids—nutritionallyimportant proteins found in only small amounts in cereals and grains. Nutrients and minerals in seafood can improve brain development and reproduction and there are strong links between fish and heart health. Similarly, other organisms such as phytoplankton and invertebrates possess several nutrients of health importance. All of these benefits are critical to global nutrition and particularly important to food-deficient, low-income countries. The first book of its kind, Nutritional Marine Life explores the nutritional characteristics of the different species of the following groups of edible marine life: Phytoplankton Seaweeds and marsh plants Jellyfish Crustaceans Mollusks Echinoderms Prochordate Fish Turtles Mammals For each species, the book discusses its classification, common name, habitat, global distribution, biological features, and nutritional facts. The highly accessible style and high-quality photographs make it easy to identify nutritionally and commercially important marine species. The book is ideal for students and researchers in fisheries and aquaculture and in related marine biology and biotechnology disciplines. It is also suitable as a reference for practitioners in those fields as well as dieticians, food scientists, and physicians interested in knowing about the health benefits of seafood.

Read more less

Written as the successor to Virtual World Design: Creating Immersive Virtual Environments, this book carries the ideas brought forward in its predecessor to new levels of virtual world design exploration and experimentation. Written by an Emmy award-winning designer with 22 years of experience creating virtual environments for television and online communities, Extending Virtual Worlds: Advanced Design for Virtual Environments explores advanced topics such as multi-regional design, game-based sims, and narrative structure for environments.The book provides bedrock knowledge and practical examples of how to leverage design concepts within the intertwined structures of physics engines, level of detail (LOD) systems, and advanced material editors. It also shows designers new ways to influence the experience of virtual world visitors through immersive narrative and storytelling. With over 150 illustrations and 10 step-by-step projects that include the necessary 3D models and modular components, it delivers hours of stimulating creative challenges for people working in public virtual worlds or on private grids.By using this book, novices and advanced users will deepen their understanding of game design and how it can be applied to creating game-based virtual environments. It also serves as a foundational text for class work in distance learning, simulation, and other learning technologies that use virtual environments.

Read more less

Recently, there has been a fundamental shift in the global health and wellness industry from disease treatment to preventing chronic diseases. The use of nutraceuticals and functional foods in prevention efforts could lead to a decreased dependency on drugs. The pharmaceutical industry recognizes this shift; however, serious concerns have arisen regarding the claimed efficacy, quality, and safety of products used as medical foods.This book examines the consumer and industry mindshift, including the scientific evidence of these foods as effective adjuncts to pharmacotherapy during all stages of treatment of various diseases, thus indicating that pharmaceuticals and nutraceuticals can and should coexist. It details quality, safety, and efficacy of foods, drugs, and nutrients; marketing and product positioning; regulatory perspectives; biomarkers and metabolites; probiotics; food/drug interactions; and future industry trends. In addition, food bioactives represent diet-based molecules that perform physiological roles related to disease prevention and treatment. As such, a considerable overlap exists between food bioactives and drugs—this book presents the case for comparing and contrasting foods versus drugs in several models of health and disease.

Read more less

Small Area Estimation and Microsimulation Modeling is the first practical handbook that comprehensively presents modern statistical SAE methods in the framework of ultramodern spatial microsimulation modeling while providing the novel approach of creating synthetic spatial microdata. Along with describing the necessary theories and their advantages and limitations, the authors illustrate the practical application of the techniques to a large number of substantive problems, including how to build up models, organize and link data, create synthetic microdata, conduct analyses, yield informative tables and graphs, and evaluate how the findings effectively support the decision making processes in government and non-government organizations.Features Covers both theoretical and applied aspects for real-world comparative research and regional statistics production Thoroughly explains how microsimulation modeling technology can be constructed using available datasets for reliable small area statistics Provides SAS codes that allow readers to utilize these latest technologies in their own work. This book is designed for advanced graduate students, academics, professionals and applied practitioners who are generally interested in small area estimation and/or microsimulation modeling and dealing with vital issues in social and behavioural sciences, applied economics and policy analysis, government and/or social statistics, health sciences, business, psychology, environmental and agriculture modeling, computational statistics and data simulation, spatial statistics, transport and urban planning, and geospatial modeling. Dr Azizur Rahman is a Senior Lecturer in Statistics and convenor of the Graduate Program in Applied Statistics at the Charles Sturt University, and an Adjunct Associate Professor of Public Health and Biostatistics at the University of Canberra. His research encompasses small area estimation, applied economics, microsimulation modeling, Bayesian inference and public health. He has more than 60 scholarly publications including two books. Dr. Rahman’s research is funded by the Australian Federal and State Governments, and he serves on a range of editorial boards including the International Journal of Microsimulation (IJM). Professor Ann Harding, AO is an Emeritus Professor of Applied Economics and Social Policy at the National Centre for Social and Economic Modelling (NATSEM) of the University of Canberra. She was the founder and inaugural Director of this world class Research Centre for more than sixteen years, and also a co-founder of the International Microsimulation Association (IMA) and served as the inaugural elected president of IMA from 2004 to 2011. She is a fellow of the Academy of the Social Sciences in Australia. She has more than 300 publications including several books in microsimulation modeling.

Read more less

A social robot is a robot that interacts and communicates with humans or other autonomous physical agents by following social behaviors and rules attached to its role. We seem to accept the use of robots that perform dull, dirty, and dangerous jobs. But how far do we want to go with the automation of care for children and the elderly, or the killing of terrorists? Would we be setting humanity aside if we accepted such automation?Just Ordinary Robots: Automation from Love to War provides a socially involved, yet sober, view into the new age of robots. It supplies a cutting-edge look at robot technologies, including what these technologies are capable of and the ethical and regulatory questions they raise.The book surveys the various types of social robots and examines their social significance in homes, health care, traffic, the police, and the military. Considering the technical characteristics and societal expectations of robots in these areas, it explores what is possible right now in terms of robot technologies. It also looks into the social, ethical, and regulatory issues future robot technologies will create.The text provides authoritative insights into the social significance of robots for the medium and long term. Illustrating the political, administrative, and regulatory consequences related to each area, it highlights key points that need to be publicly discussed or put on the agenda by today’s politicians and policy makers.

Read more less

This book is dedicated to the field of conductive polymers, focusing on electrical interactions with biological systems. It addresses the use of conductive polymers as the conducting interface for electrical communications with the biological system, both in vitro and in vivo. It provides an overview on the chemistry and physics of conductive polymers, their useful characteristics as well as limitations, and technologies that apply conductive polymers for medical purposes. This groundbreaking resource addresses cytotoxicity and tissue compatibility of conductive polymers, the basics on electromagnetic fields, and commonly used experimental methods. Readers will also learn how cells are cultured in vitro with conductive polymers, and how conductive polymers and living tissues interact electrically. Throughout the contents, chapter authors emphasize the importance of conductive polymers in biomedical engineering and their potential applications in medicine.

Read more less

Now in its second edition, Forensic DNA Evidence Interpretation is the most comprehensive resource for DNA casework available today. Written by leaders in the fields of biology and statistics, including a contribution from Peter Gill, the father of DNA analysis, the book emphasizes the interpretation of test results and provides the necessary formulae in an easily accessible manner. This latest edition is fully updated and includes current and emerging techniques in this fast-moving field. The book begins by reviewing all pertinent biology, and then provides information on every aspect of DNA analysis. This includes modern interpretation methods and contemporary population genetic models available for estimating DNA frequencies or likelihood ratios. Following a chapter on procedures for validating databases, the text presents overviews and performance assessments of both modern sampling uncertainty methods and current paternity testing techniques, including new guidelines on paternity testing in alignment with the International Society for Forensic Genetics. Later chapters discuss the latest methods for mixture analysis, LCN (ultra trace) analysis and non-autosomal (mito, X, and Y) DNA analysis. The text concludes with an overview of procedures for disaster victim identification and information on DNA intelligence databases.Highlights of the second edition include: New information about PCR processes, heterozygote balance and back and forward stuttering New information on the interpretation of low template DNA, drop models and continuous models Additional coverage of lineage marker subpopulation effects, mixtures and combinations with autosomal markers This authoritative book provides a link among the biological, forensic, and interpretative domains of the DNA profiling field. It continues to serve as an invaluable resource that allows forensic scientists, technicians, molecular biologists and attorneys to use forensic DNA evidence to its greatest potential.

Read more less

5* Doody's Review: 98/100!Featuring a new author team, this seminal book has been completely updated and significantly expanded. Following an outline of the basic elements of ophthalmic science relevant to study and practice, the authors provide a detailed description and discussion of each condition including etiology, clinical signs, diagnosis, prognosis, and therapy, as well as a section dedicated to presumed inherited eye disorders. The focus throughout remains on the clinical needs of the practitioner and the student. Beautifully illustrated in full color, the book is aimed at trainee and practicing veterinarians interested in all types of ophthalmic diseases and disorders. Although the focus is on small animals, there is additional material on the horse and the cow. For this edition, a diverse group of authors from many geographic regions of training and practice offer a breadth of clinical expertise.

Read more less

Metal–air and metal–sulfur batteries (MABs/MSBs) represent one of the most efficient-energy storage technologies, with high round trip efficiency, a long life cycle, fast response at peak demand/supply of electricity, and decreased weight due to the use of atmospheric oxygen as one of the main reactants. This book presents an overview of the main MABs/MSBs from fundamentals to applications. Recent technological trends in their development are reviewed. It also offers a detailed analysis of these batteries at the material, component, and system levels, allowing the reader to evaluate the different approaches of their integration. The book provides a systematic overview of the components, design, and integration, and discusses current technologies, achievements, and challenges, as well as future directions. Each chapter focuses on a particular battery type including zinc–air batteries, lithium–air batteries, aluminum–air batteries, magnesium–air batteries, lithium–sulfur batteries, and vanadium–air redox flow batteries, and metal–sulfur batteries. Features the most recent advances made in metal–air/metal–sulfur batteries.Describes cutting-edge materials and technology for metal–air/metal–sulfur batteries.Includes both fundamentals and applications, which can be used to guide and promote materials as well as technology development for metal–air/metal–sulfur batteries.Provides a systematic overview of the components, design, and integration, and discusses current technologies, achievements, and challenges, as well as future directions.Covers a variety of battery types in depth, such as zinc–air batteries, lithium–air batteries, aluminum–air batteries, magnesium–air batteries, lithium–sulfur batteries, vanadium–air redox flow batteries, and metal–sulfur batteries.

Read more less

Environmental professionals are often called upon to find solutions to environmental degradation problems or to lead the way in planning to prevent them. Because they come mainly from the environmental and science disciplines, most environmental professionals have limited training in the fundamentals of economics. This book is designed to provide those professionals not only with the basic principles of economics for foundational purposes but also the economic pros and cons to consider when making critical decisions on environmental issues.Economics for Environmental Professionals provides a fully explanatory, quantitative, and practical introduction to a wide range of topics that make up the science of environmental economics. Moreover, it showcases the power of economic principles to explain and predict issues and current events impacting the environment. It discusses the economics relevant to the environmental mediums of air, water, and land and provides pertinent information on air toxics, hazardous wastes, and other related topics. It provides environmental professionals with the education not only to understand the nuts and bolts of economic analysis but also to conduct economic analyses.Throughout the book, the author joins economics and environmental practice with common-sense approaches and practical real-world examples. Designed to stimulate thought, the book explores strategies for maintaining a safe environment without excessive regulation and cost. With the information in this book, environmental professionals will have an understanding of the framework in which environmental problems exist, what they cost, how to pay for them, and what the payback is (if any).

Read more less

Event-based systems are a class of reactive systems deployed in a wide spectrum of engineering disciplines including control, communication, signal processing, and electronic instrumentation. Activities in event-based systems are triggered in response to events usually representing a significant change of the state of controlled or monitored physical variables. Event-based systems adopt a model of calls for resources only if it is necessary, and therefore, they are characterized by efficient utilization of communication bandwidth, computation capability, and energy budget. Currently, the economical use of constrained technical resources is a critical issue in various application domains because many systems become increasingly networked, wireless, and spatially distributed.Event-Based Control and Signal Processing examines the event-based paradigm in control, communication, and signal processing, with a focus on implementation in networked sensor and control systems. Featuring 23 chapters contributed by more than 60 leading researchers from around the world, this book covers: Methods of analysis and design of event-based control and signal processing Event-driven control and optimization of hybrid systems Decentralized event-triggered control Periodic event-triggered control Model-based event-triggered control and event-triggered generalized predictive control Event-based intermittent control in man and machine Event-based PID controllers Event-based state estimation Self-triggered and team-triggered control Event-triggered and time-triggered real-time architectures for embedded systems Event-based continuous-time signal acquisition and DSP Statistical event-based signal processing in distributed detection and estimation Asynchronous spike event coding technique with address event representation Event-based processing of non-stationary signals Event-based digital (FIR and IIR) filters Event-based local bandwidth estimation and signal reconstruction Event-Based Control and Signal Processing is the first extensive study on both event-based control and event-based signal processing, presenting scientific contributions at the cutting edge of modern science and engineering.

Read more less

Pseudolinear Functions and Optimization is the first book to focus exclusively on pseudolinear functions, a class of generalized convex functions. It discusses the properties, characterizations, and applications of pseudolinear functions in nonlinear optimization problems.The book describes the characterizations of solution sets of various optimization problems. It examines multiobjective pseudolinear, multiobjective fractional pseudolinear, static minmax pseudolinear, and static minmax fractional pseudolinear optimization problems and their results. The authors extend these results to locally Lipschitz functions using Clarke subdifferentials. They also present optimality and duality results for h-pseudolinear and semi-infinite pseudolinear optimization problems.The authors go on to explore the relationships between vector variational inequalities and vector optimization problems involving pseudolinear functions. They present characterizations of solution sets of pseudolinear optimization problems on Riemannian manifolds as well as results on pseudolinearity of quadratic fractional functions. The book also extends n-pseudolinear functions to pseudolinear and n-pseudolinear fuzzy mappings and characterizations of solution sets of pseudolinear fuzzy optimization problems and n-pseudolinear fuzzy optimization problems. The text concludes with some applications of pseudolinear optimization problems to hospital management and economics.This book encompasses nearly all the published literature on the subject along with new results on semi-infinite nonlinear programming problems. It will be useful to readers from mathematical programming, industrial engineering, and operations management.

Read more less

Regulatory agencies worldwide have issued directives or such requirements for air quality standards in embryology laboratories. This practical guide reviews the application of clean room technology or controlled environments specifically suited for Assisted Reproductive Technology (ART) Units. Its comprehensive coverage includes material on airborne particles and volatile organic compounds, including basic concepts, regulation, construction, materials, certification, clinical results in humans, and more.

Read more less

Carbon-based nanomaterials are rapidly emerging as one of the most fascinating materials in the twenty-first century. Chemical Functionalization of Carbon Nanomaterials: Chemistry and Applications provides a thorough examination of carbon nanomaterials, including their variants and how they can be chemically functionalized. It also gives a comprehensive overview of current advanced applications of functionalized carbon nanomaterials, including the automotive, packaging, coating, and biomedical industries.The book covers modern techniques to characterize chemically functionalized carbon nanomaterials as well as characterization of surface functional groups. It includes contributions from international leaders in the field who highlight the multidisciplinary and interdisciplinary flexibility of functionalized carbon nanomaterials. The book illustrates how natural drawbacks to carbon nanomaterials, such as low solubility, can be countered by surface modifications and shows how to make modifications.It discusses developments in the use of carbon nanomaterials in several critical areas in scientific research and practice, including analytical chemistry, drug delivery, and water treatment. It explores market opportunities due to the versatility and increasing applicability of carbon nanomaterials. It also gives suggestions on the direction of the field from its current point, paving the way for future developments and finding new applications. Chemical Functionalization of Carbon Nanomaterials: Chemistry and Applications is a significant collection of findings in a rapidly developing field. It gives an in-depth look at the current achievements of research and practice while pointing you ahead to new possibilities in functionalizing and using carbon nanomaterials.

Read more less

Dermoscopy is a noninvasive skin imaging technique that uses optical magnification and either liquid immersion or cross-polarized lighting to make subsurface structures more easily visible when compared to conventional clinical images. It allows for the identification of dozens of morphological features that are particularly important in identifying malignant melanoma. Dermoscopy Image Analysis summarizes the state of the art of the computerized analysis of dermoscopy images. The book begins by discussing the influence of color normalization on classification accuracy and then: Investigates gray-world, max-RGB, and shades-of-gray color constancy algorithms, showing significant gains in sensitivity and specificity on a heterogeneous set of images Proposes a new color space that highlights the distribution of underlying melanin and hemoglobin color pigments, leading to more accurate classification and border detection results Determines that the latest border detection algorithms can achieve a level of agreement that is only slightly lower than the level of agreement among experienced dermatologists Provides a comprehensive review of various methods for border detection, pigment network extraction, global pattern extraction, streak detection, and perceptually significant color detection Details a computer-aided diagnosis (CAD) system for melanomas that features an inexpensive acquisition tool, clinically meaningful features, and interpretable classification feedback Presents a highly scalable CAD system implemented in the MapReduce framework, a novel CAD system for melanomas, and an overview of dermatological image databases Describes projects that made use of a publicly available database of dermoscopy images, which contains 200 high-quality images along with their medical annotations Dermoscopy Image Analysis not only showcases recent advances but also explores future directions for this exciting subfield of medical image analysis, covering dermoscopy image analysis from preprocessing to classification.

Read more less

This book is a result of the authors’ more than 40 years of study on the behavior, populations, and heavy metals in the colonial waterbirds nesting in Barnegat Bay and the nearby estuaries and bays in the Northeastern United States. From Boston Harbor to the Chesapeake, based on longitudinal studies of colonial waterbirds, it provides a clear picture of the toxic trends and effects of heavy metals in the aquatic environment. The authors take a food web, ecosystem approach to contaminants, using population dynamics, habitat selection, and inputs to the bay to examine metal levels. They also look at the human dimension, discuss what metals in birds tell us about human exposure, and describe stakeholder involvement in these issues.The book covers numbers and dynamics, colony sites and locations, and prey contaminant levels, and compares them to other comparable coastal estuaries. It uses colonial waterbirds as the focal point for an ecosystem approach to metals that begins with prey fish and goes through invertebrates to humans. Additionally, it provides information based on long-term integrative studies the authors have done on metal levels and bird species and compares the findings with data from the Harbor Estuaries Program, other Northeast bays, the Great Lakes, and the Wadden Sea.

Read more less

An important factor that affects the duration, complexity and cost of a clinical trial is the endpoint used to study the treatment’s efficacy. When a true endpoint is difficult to use because of such factors as long follow-up times or prohibitive cost, it is sometimes possible to use a surrogate endpoint that can be measured in a more convenient or cost-effective way. This book focuses on the use of surrogate endpoint evaluation methods in practice, using SAS and R.

Read more less

Handbook of Big Data provides a state-of-the-art overview of the analysis of large-scale datasets. Featuring contributions from well-known experts in statistics and computer science, this handbook presents a carefully curated collection of techniques from both industry and academia. Thus, the text instills a working understanding of key statistical and computing ideas that can be readily applied in research and practice.Offering balanced coverage of methodology, theory, and applications, this handbook: Describes modern, scalable approaches for analyzing increasingly large datasets Defines the underlying concepts of the available analytical tools and techniques Details intercommunity advances in computational statistics and machine learning Handbook of Big Data also identifies areas in need of further development, encouraging greater communication and collaboration between researchers in big data sub-specialties such as genomics, computational biology, and finance.

Read more less

Nature-Inspired Computing: Physics and Chemistry-Based Algorithms provides a comprehensive introduction to the methodologies and algorithms in nature-inspired computing, with an emphasis on applications to real-life engineering problems. The research interest for Nature-inspired Computing has grown considerably exploring different phenomena observed in nature and basic principles of physics, chemistry, and biology. The discipline has reached a mature stage and the field has been well-established. This endeavour is another attempt at investigation into various computational schemes inspired from nature, which are presented in this book with the development of a suitable framework and industrial applications. Designed for senior undergraduates, postgraduates, research students, and professionals, the book is written at a comprehensible level for students who have some basic knowledge of calculus and differential equations, and some exposure to optimization theory. Due to the focus on search and optimization, the book is also appropriate for electrical, control, civil, industrial and manufacturing engineering, business, and economics students, as well as those in computer and information sciences. With the mathematical and programming references and applications in each chapter, the book is self-contained, and can also serve as a reference for researchers and scientists in the fields of system science, natural computing, and optimization.

Read more less

Introduction to Visual Computing: Core Concepts in Computer Vision, Graphics, and Image Processing covers the fundamental concepts of visual computing. Whereas past books have treated these concepts within the context of specific fields such as computer graphics, computer vision or image processing, this book offers a unified view of these core concepts, thereby providing a unified treatment of computational and mathematical methods for creating, capturing, analyzing and manipulating visual data (e.g. 2D images, 3D models). Fundamentals covered in the book include convolution, Fourier transform, filters, geometric transformations, epipolar geometry, 3D reconstruction, color and the image synthesis pipeline.The book is organized in four parts. The first part provides an exposure to different kinds of visual data (e.g. 2D images, videos and 3D geometry) and the core mathematical techniques that are required for their processing (e.g. interpolation and linear regression.) The second part of the book on Image Based Visual Computing deals with several fundamental techniques to process 2D images (e.g. convolution, spectral analysis and feature detection) and corresponds to the low level retinal image processing that happens in the eye in the human visual system pathway.The next part of the book on Geometric Visual Computing deals with the fundamental techniques used to combine the geometric information from multiple eyes creating a 3D interpretation of the object and world around us (e.g. transformations, projective and epipolar geometry, and 3D reconstruction). This corresponds to the higher level processing that happens in the brain combining information from both the eyes thereby helping us to navigate through the 3D world around us.The last two parts of the book cover Radiometric Visual Computing and Visual Content Synthesis. These parts focus on the fundamental techniques for processing information arising from the interaction of light with objects around us, as well as the fundamentals of creating virtual computer generated worlds that mimic all the processing presented in the prior sections.The book is written for a 16 week long semester course and can be used for both undergraduate and graduate teaching, as well as a reference for professionals.

Read more less

The term health technology refers to drugs, devices, and programs that can improve and extend quality of life. As decision-makers struggle to find ways to reduce costs while improving health care delivery, health technology assessments (HTA) provide the evidence required to make better-informed decisions.This is the first book that focuses on the statistical options of HTAs, to fully capture the value of health improvements along with their associated economic consequences. After reading the book, readers will better understand why some health technologies receive regulatory or reimbursement approval while others do not, what can be done to improve the chances of approval, as well as common shortcomings of submissions for drug and device reimbursement.The book begins by contrasting the differences between regulatory approval and reimbursement approval. Next, it reviews the principles and steps for conducting an HTA, including the reasons why different agencies will have a different focus for their scope in the HTA.Supplying an accessible introduction to the various statistical options for different methods in an HTA, the book identifies the links to regulatory and reimbursement decisions for each option. It highlights many of the methodological advances that have occurred since HTA research began, to provide researchers and decision-makers with a cutting-edge framework. It also details the logical basis for the methods along with simple instructions on how to conduct the various techniques.Both authors have considerable experience in generating evidence for submissions and reviewing submissions to decision-makers for funding. One of the authors has also received a nationally recognized lifetime achievement award in this area.

Read more less

Good Manufacturing Practice (GMP) ensures medicinal products are produced consistently and controlled to the quality standards appropriate for their intended use and as required by product specifications or marketing authorization. Annex 11 details the European Medicines Agency (EMA) GMP requirements for computer systems.The purpose of Annex 11 is to provide the EMA healthcare industry with consistent criteria for effective implementation, control, and use of computer systems. EU Annex 11 Guide to Computer Validation Compliance for the Worldwide Health Agency GMP supplies practical information to facilitate compliance with computer system GMP requirements, while highlighting and integrating the Annex 11 guidelines into the computer compliance program.The ideas presented in this book are based on the author’s 25 years of experience with computer validation in the healthcare industry with various computer systems development, maintenance, and quality functions. The book details a practical approach to increase efficiency and to ensure that software development and maintenance are achieved correctly.Examining the implementation of the computer systems validation entirely based on EU Annex 11, the book includes examples from laboratory, clinical, and manufacturing computer systems. It also discusses electronic record integrity associated with stored information.

Read more less

Divided roughly into two sections, this book provides a brief history of the development of ECG along with heart rate variability (HRV) algorithms and the engineering innovations over the last decade in this area. It reviews clinical research, presents an overview of the clinical field, and the importance of heart rate variability in diagnosis. The book then discusses the use of particular ECG and HRV algorithms in the context of clinical applications.

Read more less