Search results for ""taylor francis inc""

Cell Membrane Nanodomains: From Biochemistry to Nanoscopy describes recent advances in our understanding of membrane organization, with a particular focus on the cutting-edge imaging techniques that are making these new discoveries possible. With contributions from pioneers in the field, the book explores areas where the application of these novel techniques reveals new concepts in biology. It assembles a collection of works where the integration of membrane biology and microscopy emphasizes the interdisciplinary nature of this exciting field.Beginning with a broad description of membrane organization, including seminal work on lipid partitioning in model systems and the roles of proteins in membrane organization, the book examines how lipids and membrane compartmentalization can regulate protein function and signal transduction. It then focuses on recent advances in imaging techniques and tools that foster further advances in our understanding of signaling nanoplatforms. The coverage includes several diffraction-limited imaging techniques that allow for measurements of protein distribution/clustering and membrane curvature in living cells, new fluorescent proteins, novel Laurdan analyses, and the toolbox of labeling possibilities with organic dyes. Since superresolution optical techniques have been crucial to advancing our understanding of cellular structure and protein behavior, the book concludes with a discussion of technologies that are enabling the visualization of lipids, proteins, and other molecular components at unprecedented spatiotemporal resolution. It also explains the ins and outs of the rapidly developing high- or superresolution microscopy field, including new methods and data analysis tools that exclusively pertain to these techniques.This integration of membrane biology and advanced imaging techniques emphasizes the interdisciplinary nature of this exciting field. The array of contributions from leading world experts makes this book a valuable tool for the visualization of signaling nanoplatforms by means of cutting-edge optical microscopy tools.

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Optimize Designs in Less TimeAn essential element of equipment and system design, computer aided design (CAD) is commonly used to simulate potential engineering problems in order to help gauge the magnitude of their effects. Useful for producing 3D models or drawings with the selection of predefined objects, Computer Aided Design: A Conceptual Approach directs readers on how to effectively use CAD to enhance the process and produce faster designs with greater accuracy. Learn CAD Quickly and EfficientlyThis handy guide provides practical examples based on different CAD systems, and incorporates automation, mechanism, and customization guidelines, as well as other outputs of CAD in the design process. It explains the mathematical tools used in related operations and covers general topics relevant to any CAD program. Comprised of 12 chapters, this instructional reference addresses: Automation concepts and examples Mechanism design concepts Tie reduction through customization Practical industrial component and system design Reduce Time by Effectively Using CAD Computer Aided Design: A Conceptual Approach concentrates on concept generation, functions as a tutorial for learning any CAD software, and was written with mechanical engineering professionals and post-graduate engineering students in mind.

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A Straightforward Text Summarizing All Aspects of Process ControlTextile manufacturing is one of the largest industries in the world, second only to agriculture. Spinning covers a prominent segment in textile manufacturing, and this budding industry continues to thrive and grow. Process Management in Spinning considers aspect of process management, and offers insight into the process control procedures and methods of spinning. Focusing on the technology as well as the management of the process, it examines both the economic and technological advancements currently taking place in the spinning industry. This text takes a close look at the advancing technology in manufacturing and process, and product quality control. It provides a basic overview of the subject, and also presents applications of this technology for practicing engineers.Incorporates Industry-Based, Real-World ExamplesThe book contains 15 chapters that specifically address the stages of process control, energy management methods, humidification and ventilation systems basics, pollution management, process management tools, productivity, waste control, material handling, and other aspects of spinning mills. It also includes real-time case studies involving typical problems that arise in spinning processes and strategies used to contain them. The author provides a broad outlook on various topics including mixing, winding, raw material and optimizing raw material properties, bale management, yarn engineering systems, processing, and process management systems. He also details the defects associated with each and every process with causes, effects, and control measures. The book addresses process management as it relates to productivity, quality, and costs, as well as process control as it relates to man, machine, and material. Provides the scientific method for optimization/optimizing the

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With breadth and depth of coverage, the Encyclopedia of Computer Science and Technology, Second Edition has a multi-disciplinary scope, drawing together comprehensive coverage of the inter-related aspects of computer science and technology. The topics covered in this encyclopedia include: General and reference Hardware Computer systems organization Networks Software and its engineering Theory of computation Mathematics of computing Information systems Security and privacy Human-centered computing Computing methodologies Applied computing Professional issues Leading figures in the history of computer science The encyclopedia is structured according to the ACM Computing Classification System (CCS), first published in 1988 but subsequently revised in 2012. This classification system is the most comprehensive and is considered the de facto ontolo

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Aesthetic rejuvenation now encompasses so many topics that practitioners in one area may feel out of touch with developments in other areas in the same field. With over 70 chapters, over 1200 figures (many in full color), over 80 tables, and over 20 videos, from an international list of contributors, under an eminent team of editors, Cosmetic Medicine & Surgery is a comprehensive and authoritative resource. It covers a wide spectrum of topics including the fundamental aspects, cosmetic aspects, minimally invasive surgery, the aesthetic facelift, and many others in this most high-profile of medical and surgical specialties.Print Versions of this book also include access to the ebook version.

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High Frequency Communication and Sensing: Traveling-Wave Techniques introduces novel traveling wave circuit techniques to boost the performance of high-speed circuits in standard low-cost production technologies, like complementary metal oxide semiconductor (CMOS). A valuable resource for experienced analog/radio frequency (RF) circuit designers as well as undergraduate-level microelectronics researchers, this book: Explains the basics of high-speed signaling, such as transmission lines, distributed signaling, impedance matching, and other common practical RF background material Promotes a dual-loop coupled traveling wave oscillator topology, the trigger mode distributed wave oscillator, as a high-frequency multiphase signal source Introduces a force-based starter mechanism for dual-loop, even-symmetry, multiphase traveling wave oscillators, presenting a single-loop version as a force mode distributed wave antenna (FMDWA) Describes higher-frequency, passive inductive, and quarter-wave-length-based pumped distributed wave oscillators (PDWOs) Examines phased-array transceiver architectures and front-end circuits in detail, along with distributed oscillator topologies Devotes a chapter to THz sensing, illustrating a unique method of traveling wave frequency multiplication and power combining Discusses various data converter topologies, such as digital-to-analog converters (DACs), analog-to-digital converters (ADCs), and GHz-bandwidth sigma-delta modulators Covers critical circuits including phase rotators and interpolators, phase shifters, phase-locked loops (PLLs), delay-locked loops (DLLs), and more It is a significantly challenging task to generate and distribute high-speed clocks. Multiphase low-speed clocks with sharp transition are proposed to be a better option to accommodate the desired timing resolution. High Frequency Communication and Sensing: Traveling-Wave Techniques provides new horizons in the quest for greater speed and performance.

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Translating Biomaterials for Bone Graft: Bench-top to Clinical Applications brings together the current translational research in bone tissue engineering, from design to application – from materials, drugs and biologic delivery used for bone graft applications to pre-clinical and clinical considerations. The book also discusses the regulatory approval pathways, which involves consideration of the class of devices; whether they are similar to existing solutions, minimal manipulation of donor tissue or completely novel materials, drugs and biologics. These considerations drive the ability to successfully transition the latest generations of bone graft materials into the clinics. Chapters come from materials scientists, clinicians, researchers, and consultants and provide a holistic understanding of the field. As such, the book is a state-of-the-art reference to bone therapies and should appeal to clinicians, scientists, as well as students interested in the current research and/or practices in the field of bone regeneration and restoration.

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Digital computers have revolutionized computation and transformed how computers are used to control systems in real life, giving birth to real-time systems. Furthermore, massive developments in the communications domain have made it possible for real-time systems to perform coordinated actions over communication interfaces, resulting in the evolution of distributed real-time systems.Real-Time and Distributed Real-Time Systems: Theory and Applications presents a variety of techniques to design, analyze, implement, verify, and validate such systems. The book begins by introducing the basic principles of real-time and distributed real-time systems and then: Delivers a detailed analysis of a number of common, real-time communication protocols Discusses advancements beyond the standard-switched Ethernet, including multi-stream transmission control protocol/internet protocol (TCP/IP) Depicts the design of distributed real-time systems applications using methodology based on a finite state machine (FSM) representation of a real-time system and its corresponding implementation using Simulink® Stateflow® Demonstrates how MATLAB® can be used to develop real-time applications and integrate those applications over a communication network to form a distributed real-time system Describes the MATLAB/Simulink-based TrueTime as a tool used for the simulation of protocols and distributed real-time system applications in a MATLAB environment Delineates the classification of distributed real-time systems applications in terms of failure criticality and severity, safety and integrity levels, life cycle stages, and verification and validation techniques Individual chapters are supplemented by numerical and analytical problems or simulation exercises to ensure the reader gains a solid grasp of the concepts.

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Guidance on Protecting and Extending the Life of Suspension BridgesSuspension bridges are graceful, aesthetic, and iconic structures. Due to their attractiveness and visibility, they are well-known symbols of major cities and countries in the world. They are also an essential form of transportation infrastructure built across large bodies of water. Despite being expensive to build, they are economical structures for the lengths they span. They have evolved significantly from the basic concept dating back to 200 BC China through the first design for a bridge resembling a modern suspension bridge, attributed to Fausto Veranzio in 1595, to present-day span lengths close to two kilometers.Many of these bridges carry significant traffic and their upkeep is very important to maintain transportation mobility. They offer grace and functionality, yet are extremely complex to construct and maintain. Bridge owners spend a considerable amount of time and resources to ensure uninterrupted service, safety, and security for users. Inspection, evaluation, maintenance, and rehabilitation have evolved significantly. Modern materials and innovative design and construction practices have been integrated into these bridges to maintain durability and extended service life. Captures the Experience of More Than 20 Suspension Bridge OperatorsInspection, Evaluation and Maintenance of Suspension Bridges is written by the bridge owners and practitioners who strive to cost-effectively manage these bridges. It is invaluable to everyone interested not only in suspension bridges but in the upkeep of any bridges—students, designers, maintenance personnel, contractors, and owners. Describes the evolution and trends in the operation and maintenance of cable supported bridges Contains the latest methods for evaluating cable supported bridge capacities and durability Presents suspension bridge security risk management aspects and Bayesian network-based methodology for risk evaluation This volume discusses state-of-the-art practice in suspension bridge inspection, evaluation, and rehabilitation methods used worldwide, described by the personnel directly involved with managing them. Its companion volume presents detailed case studies of specific bridges to give a comprehensive picture of how suspension bridges are maintained around the world.

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This book introduces fundamental concepts and theories in pervasive computing as well as its key technologies and applications. It explains how to design and implement pervasive middleware and real application systems, covering nearly all aspects related to pervasive computing. Key technologies in the book include pervasive computing-oriented resource management and task migration, mobile pervasive transaction, human computer interface, and context collection-oriented wireless sensor networks.

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An In-Depth, Practical Guide to GPGPU Programming Using Direct3D 11GPGPU Programming for Games and Science demonstrates how to achieve the following requirements to tackle practical problems in computer science and software engineering: Robustness Accuracy Speed Quality source code that is easily maintained, reusable, and readable The book primarily addresses programming on a graphics processing unit (GPU) while covering some material also relevant to programming on a central processing unit (CPU). It discusses many concepts of general purpose GPU (GPGPU) programming and presents practical examples in game programming and scientific programming.The author first describes numerical issues that arise when computing with floating-point arithmetic, including making trade-offs among robustness, accuracy, and speed. He then shows how single instruction multiple data (SIMD) extensions work on CPUs since GPUs also use SIMD.The core of the book focuses on the GPU from the perspective of Direct3D 11 (D3D11) and the High Level Shading Language (HLSL). This chapter covers drawing 3D objects; vertex, geometry, pixel, and compute shaders; input and output resources for shaders; copying data between CPU and GPU; configuring two or more GPUs to act as one; and IEEE floating-point support on a GPU.The book goes on to explore practical matters of programming a GPU, including code sharing among applications and performing basic tasks on the GPU. Focusing on mathematics, it next discusses vector and matrix algebra, rotations and quaternions, and coordinate systems. The final chapter gives several sample GPGPU applications on relatively advanced topics.Web ResourceAvailable on a supporting website, the author’s fully featured Geometric Tools Engine for computing and graphics saves you from having to write a large amount of infrastructure code necessary for even the simplest of applications involving shader programming. The engine provides robust and accurate source code with SIMD when appropriate and GPU versions of algorithms when possible.

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Exciting new developments are enabling sensors to go beyond the realm of simple sensing of movement or capture of images to deliver information such as location in a built environment, the sense of touch, and the presence of chemicals. These sensors unlock the potential for smarter systems, allowing machines to interact with the world around them in more intelligent and sophisticated ways.Featuring contributions from authors working at the leading edge of sensor technology, Technologies for Smart Sensors and Sensor Fusion showcases the latest advancements in sensors with biotechnology, medical science, chemical detection, environmental monitoring, automotive, and industrial applications. This valuable reference describes the increasingly varied number of sensors that can be integrated into arrays, and examines the growing availability and computational power of communication devices that support the algorithms needed to reduce the raw sensor data from multiple sensors and convert it into the information needed by the sensor array to enable rapid transmission of the results to the required point. Using both SI and US units, the text: Provides a fundamental and analytical understanding of the underlying technology for smart sensors Discusses groundbreaking software and sensor systems as well as key issues surrounding sensor fusion Exemplifies the richness and diversity of development work in the world of smart sensors and sensor fusion Offering fresh insight into the sensors of the future, Technologies for Smart Sensors and Sensor Fusion not only exposes readers to trends but also inspires innovation in smart sensor and sensor system development.

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More than 7 billion people inhabit the earth and all of them are subject to aging. This book is aimed at persons interested in a molecular explanation of how our cells age. Human Longevity: Omega-3 Fatty Acids, Bioenergetics, Molecular Biology, and Evolution is built on the proposition that we age as our mitochondria age. It suggests a revised version of Harman’s famous hypothesis featuring mitochondrial oxidative and energy stresses as the root causes of aging. Human cells are protected from the ravages of aging by a battery of defensive systems including some novel mechanisms against membrane oxidation introduced in this book. This concept is consistent with recent discoveries showing that mitochondria-targeted antioxidants prevent Huntington’s disease, Parkinson’s disease, and traumatic brain disease in animal models of neurodegeneration.This book explores a unified theory of aging based on bioenergetics. It covers a variety of topics including an introduction to the science of human aging, the Darwinian selection of membranes enabling longevity, a revised mitochondrial membrane hypothesis of aging, and various mechanisms that protect human mitochondrial membranes, thereby enabling longevity.

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For more than a century, bioactive heterocycles have formed one of the largest areas of research in organic chemistry. They are important from a biological and industrial point of view as well as to the understanding of life processes and efforts to improve the quality of life. Heterogeneous Catalysis: A Versatile Tool for the Synthesis of Bioactive Heterocycles highlights the recent methodologies used in the synthesis of such bioactive systems and focuses on the role of heterogeneous catalysis in the design and synthesis of various biologically active heterocyclic compounds of pharmacological interest. Topics include: Synthetic protocols for the construction of heterocyclic systems employing silica-bound catalysts Recent advances in heterogeneous copper-catalyzed reactions for the synthesis of bioactive heterocycles Features of silica-based heterogeneous catalysts, such as abundance, ease of use, and stability Ultrasound as an effective tool for accelerating reactions Organic transformations catalyzed by nano-ZnO as a valuable heterogeneous catalyst Heterogeneous catalysts employed in the synthesis of coumarins Heterocyclizations in the presence of silver salts Home-made organometallic silica sources, known as silatranes Reflecting the focused studies currently conducted in these areas, the book also examines anticancer, antifungal, antibacterial, anti-HIV, anti-inflammatory, antioxidant, and many more biological activities of heterocyclic compounds. It is essential reading for postgraduate and research scholars in the fields of biochemistry, chemical biology, medicinal chemistry and pharmaceutical chemistry.

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Globalization and the easy movement of people, weapons, and toxins across borders has transformed security into a transnational phenomenon. Preventing transnational security threats has proven to be a very difficult challenge for governments and institutions around the world. Transnational Security addresses these issues, which are at the forefront of every global security professional’s agenda.This book analyzes the most pressing current transnational security threats, including weapons of mass destruction, terrorism, organized crime, cybercrime, natural disasters, human-made disasters, infectious diseases, food insecurity, water insecurity, and energy insecurity. It considers the applicable international laws and examines how key international organizations are dealing with these issues.The author uses a combination of theory and real-world examples to illustrate the transnational nature of security risks. By providing a detailed account of the different threats, countermeasures, and their implications for a number of different fields—law, public policy and administration, security, and criminology—this book will be an extremely useful resource for academicians, practitioners, and graduate and upper-level undergraduate students in these areas.

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Nanosilicon: Properties, Synthesis, Applications, Methods of Analysis and Control examines the latest developments on the physics and chemistry of nanosilicon. The book focuses on methods for producing nanosilicon, its electronic and optical properties, research methods to characterize its spectral and structural properties, and its possible applications.The first part of the book covers the basic properties of semiconductors, including causes of the size dependence of the properties, structural and electronic properties, and physical characteristics of the various forms of silicon. It presents theoretical and experimental research results as well as examples of porous silicon and quantum dots.The second part discusses the synthesis of nanosilicon, modification of the surface of nanoparticles, and properties of the resulting particles. The authors give special attention to the photoluminescence of silicon nanoparticles.The third part describes methods used for studying and controlling the structure and properties of nanocrystalline silicon. These methods include standard ones, such as electron microscopy, spectroscopy, and diffraction, as well as novel techniques, such as femtosecond spectroscopy, ultrafast electron nanocrystallography, and dynamic transmission electron microscopy.The fourth part details some of the practical applications of nanocrystalline silicon, including the use of nanoparticles as additives–absorbers of UV radiation in sunscreens.Incorporating much of the authors’ own extensive research results, this book provides a systematic account of the scientific problems of nanosilicon and its potential practical applications. It will help readers understand current and emerging applications and research methods of this unique material.

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Isotope Ratio Mass Spectrometry of Light Gas-Forming Elements explores different methods of isotope analysis, including spark, secondary ion, laser, glow discharge, and isotope ratio mass spectrometry. It explains how to evaluate the isotopic composition of light elements (H, C, N, O) in solid, liquid, and gaseous samples of organic and inorganic substances, as well as: Presents a universal, economical, simple, and rapid technique for sample preparation of organic substances to measure the isotopic composition of carbon Describes how to determine microbial mineralization of organic matter in soil and the effect of exogenous substrates on environmental sustainability Examines use of the isotopic composition of n-alkanes from continental vegetation to study the paleoclimate and plant physiology Proposes a systematic approach to identifying tobacco areas of origin and tobacco products based on data from the isotopic composition of light elements Discusses ways to detect doping drugs and suggests results assessment criteria based on determining reference intervals for endogenous markers Reviews methods of release of gases from inclusions of rocks and minerals for further implementation of isotope mass spectrometric analysis Considers use of optical isotope analyzers for determining the isotopic composition of carbon in CO2 and of hydrogen and oxygen in water Providing a complete picture of the latest advancements in the field, Isotope Ratio Mass Spectrometry of Light Gas-Forming Elements aids readers from a variety of disciplines in identifying the fundamental processes in biological, ecological, and geological systems and in revealing the subtle features of many physicochemical processes and chemical transformations.

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This book provides protocols for suicide and equivocal death investigation, police action shooting investigations and a homicide supervisor's checklist. It contains state-of-the-art anatomical graphics in full color to assist the investigator in describing any injuries or wounds to the body.

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Diffractive Nanophotonics demonstrates the utility of the well-established methods of diffractive computer optics in solving nanophotonics tasks. It is concerned with peculiar properties of laser light diffraction by microoptics elements with nanoscale features and light confinement in subwavelength space regions. Written by recognized experts in this field, the book covers in detail a wide variety of advanced methods for the rigorous simulation of light diffraction. The authors apply their expertise to addressing cutting-edge problems in nanophotonics.Chapters consider the basic equations of diffractive nanophotonics and related transformations and numerical methods for solving diffraction problems under strict electromagnetic theory. They examine the diffraction of light on two-dimensional microscopic objects of arbitrary shape and present a numerical method for solving the problem of diffraction on periodic diffractive micro- and nanostructures. This method is used in modern trends in nanophotonics, such as plasmonics, metamaterials, and nanometrology. The book describes the simulation of electromagnetic waves in nanophotonic devices and discusses two methods of calculating the spatial modes of microstructured photonic crystal fibres—a relatively new class of optical fibres with the properties of photonic crystals.The book explains the theory of paraxial and non-paraxial laser beams with axial symmetry and an orbital angular momentum—called vortex beams—which are used for optical trapping and rotating micro- and nanoparticles in a ring in the cross-sectional plane of the beam. The final chapter discusses methods for calculating the force and torque exerted by the electromagnetic field focused onto the microparticle of arbitrary form, whose dimensions are comparable with the wavelength of light.

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Presenting the cutting-edge results of new device developments and circuit implementations, High-Speed Devices and Circuits with THz Applications covers the recent advancements of nano devices for terahertz (THz) applications and the latest high-speed data rate connectivity technologies from system design to integrated circuit (IC) design, providing relevant standard activities and technical specifications. Featuring the contributions of leading experts from industry and academia, this pivotal work: Discusses THz sensing and imaging devices based on nano devices and materials Describes silicon on insulator (SOI) multigate nanowire field-effect transistors (FETs) Explains the theory underpinning nanoscale nanowire metal-oxide-semiconductor field-effect transistors (MOSFETs), simulation methods, and their results Explores the physics of the silicon-germanium (SiGe) heterojunction bipolar transistor (HBT), as well as commercially available SiGe HBT devices and their applications Details aspects of THz IC design using standard silicon (Si) complementary metal-oxide-semiconductor (CMOS) devices, including experimental setups for measurements, detection methods, and more An essential text for the future of high-frequency engineering, High-Speed Devices and Circuits with THz Applications offers valuable insight into emerging technologies and product possibilities that are attractive in terms of mass production and compatibility with current manufacturing facilities.

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Whenever a major event requires police intervention, questions are raised about the nature of the police response. Could the police have prevented the conflict, been better prepared, reacted more quickly? Could they have acted more forcefully or brought the altercation under control more effectively? Based upon real case studies of events from all over the world, this volume explores the complex set of factors comprising the policing of major events. Topics covered include: Police procedures in Serbia in response to sporting events and violence The 2010 World Cup in South Africa as a model of best practice in governance structures, along with the region’s struggles in routine policing initiatives Security operations at the 2010 Winter Olympic Games in Canada and the Summer Olympic and Paralympic Games in London in 2012 Community involvement to curb terrorist insurgency in North Eastern Nigeria Governmental response to Hurricane Katrina in Louisiana and Texas Revisions made to NYPD protocols following the September 11 attacks Policing strategies for major events on Aboriginal and tribal lands across Canada Other topics include the police/protestor relationship and low-profile versus high-profile policing strategies in crowd control, the growing strategy of private security in working with public police forces, and enhancing public safety in post-conflict regions. The concepts presented in Policing Major Events: Perspectives from Around the World will enable police departments to improve their readiness for policing major events across a diverse set of events and socio-political contexts. This book is a co-publication with the International Police Executive Symposium.

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A Complete Reference Covering the Latest Technology in Metal Cutting Tools, Processes, and EquipmentMetal Cutting Theory and Practice, Third Edition shapes the future of material removal in new and lasting ways. Centered on metallic work materials and traditional chip-forming cutting methods, the book provides a physical understanding of conventional and high-speed machining processes applied to metallic work pieces, and serves as a basis for effective process design and troubleshooting. This latest edition of a well-known reference highlights recent developments, covers the latest research results, and reflects current areas of emphasis in industrial practice. Based on the authors’ extensive automotive production experience, it covers several structural changes, and includes an extensive review of computer aided engineering (CAE) methods for process analysis and design. Providing updated material throughout, it offers insight and understanding to engineers looking to design, operate, troubleshoot, and improve high quality, cost effective metal cutting operations.The book contains extensive up-to-date references to both scientific and trade literature, and provides a description of error mapping and compensation strategies for CNC machines based on recently issued international standards, and includes chapters on cutting fluids and gear machining. The authors also offer updated information on tooling grades and practices for machining compacted graphite iron, nickel alloys, and other hard-to-machine materials, as well as a full description of minimum quantity lubrication systems, tooling, and processing practices. In addition, updated topics include machine tool types and structures, cutting tool materials and coatings, cutting mechanics and temperatures, process simulation and analysis, and tool wear from both chemical and mechanical viewpoints. Comprised of 17 chapters, this detailed study: Describes the common machining operations used to produce specific shapes or surface characteristics Contains conventional and advanced cutting tool technologies Explains the properties and characteristics of tools which influence tool design or selection Clarifies the physical mechanisms which lead to tool failure and identifies general strategies for reducing failure rates and increasing tool life Includes common machinability criteria, tests, and indices Breaks down the economics of machining operations Offers an overview of the engineering aspects of MQL machining Summarizes gear machining and finishing methods for common gear types, and more Metal Cutting Theory and Practice, Third Edition emphasizes the physical understanding and analysis for robust process design, troubleshooting, and improvement, and aids manufacturing engineering professionals, and engineering students in manufacturing engineering and machining processes programs.

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Based on four decades of experience and research, Navigating Strategic Decisions: The Power of Sound Analysis and Forecasting explains how to improve the decision-making process in your organization through the use of better long-term forecasts and decision support. Filled with time-tested methodologies and models, it provides you with the tools to establish the organization, processes, methods, and techniques required for analyzing and forecasting strategic decisions.Describing how to foster the conditions required for forecasts to materialize, this book will help you rank project valuations and select higher value creation projects. It also teaches you how to: Assess the commercial feasibility of large projects Apply sanity checks to forecasts and assess their resource implications Benchmark best-in-class strategic forecasting organizations, processes, and practices Identify project risks and manage project uncertainty Analyze forecasting models and scenarios to determine controllable levers Pinpoint factors needed to ensure that forecasted future states materialize as expected This book provides you with the benefit of the author’s decades of hands-on experience. In this book, John Triantis shares valuable insights on strategic planning, new product development, portfolio management, and business development groups. Describing how to provide world-class support to your corporate, market, and other planning functions, the book provides you with the tools to consistently make improved decisions that are based on hard data, balanced evaluations, well considered scenarios, and sound forecasts.

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Microscopy is at the forefront of multidisciplinary research. It was developed by physicists, made specific by chemists, and applied by biologists and doctors to better understand how the human body works. For this very reason, the field has been revolutionized in past decades.The objective of Optical Nanoscopy and Novel Microscopy Techniques is to choose some of those revolutionary ideas and serve a general audience from broad disciplines to achieve a fundamental understanding of these technologies and to better apply them in their daily research.The book begins with coverage of super-resolution optical microscopy, which discusses targeted modulation such as STED and SIM or localization methods such as PALM. It then discusses novel development of fluorescent probes, such as organic small-molecule probes, fluorescent proteins, and inorganic labels such as quantum dots. Finally, it describes advanced optical microscopy, such as fluorescence lifetime imaging, fiber optic microscopy, scanning ion conductance microscopy, and the joining of optics and acoustics—photoacoustic microscopy. Following each chapter, a detailed list of references is provided. Problems at the end of each chapter are also included.

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Nanotechnology and regenerative engineering have emerged to the forefront as the most versatile and innovative technologies to foster novel therapeutic techniques and strategies of the twenty-first century. The first edition of Nanotechnology and Tissue Engineering: The Scaffold was the first comprehensive source to explain the developments in nanostructured biomaterials for tissue engineering, the relevance of nanostructured materials in tissue regeneration, and the current applications of nanostructured scaffolds for engineering various tissues. This fully revised second edition, renamed Nanotechnology and Regenerative Engineering: The Scaffold, provides a thorough update to the existing material, bringing together these two unique areas to give a perspective of the emerging therapeutic strategies for a wide audience.New coverage includes: Updated discussion of the importance of scaffolds in tissue engineering Exploration of cellular interactions at the nanoscale Complete range of fabrication processes capable of developing nanostructured scaffolds for regenerative engineering Applications of nanostructured scaffolds for neural, skin, cardiovascular, and musculoskeletal regenerative engineering FDA approval process of nanostructure scaffolds Products based on nanostructured scaffolds Due to the unique and tissue-mimic properties of the nanostructured scaffolds, the past five years have seen a tremendous growth in nanostructured materials for biological applications. The revised work presents the current state-of-the-art developments in nanostructured scaffolds for regenerative engineering.

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Understanding how the brain is organized and visualizing its pathways and connections can be conceptually challenging. The Atlas of Functional Neuroanatomy, Third Edition addresses this challenge by presenting a clear visual guide to the human central nervous system (CNS). This edition has been completely reorganized to facilitate learning the structure and function of the CNS. The material provided gives you a solid understanding of the brain.This edition: Presents an instructive format that fosters a thorough understanding of complex neuroanatomy, emphasizing the functional perspective and supplemented with clinical aspects Incorporates enhanced illustrations, retaining the selective labeling of the nuclei and tracts (pathways) Includes new material explaining the visual system, meninges, venous system, and limbic system Features a substantial increase in the number of neuroradiological (CT and MRI) images An accompanying Web site (www.atlasbrain.com) includes the book’s illustrations along with rollover labeling, animation of the pathways and connections, a glossary, and narrated video demonstrations of the brain.

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Maintenance Audits Handbook: A Performance Measurement Framework explores the maintenance function and performance of an organization, and outlines the key aspects required for an effective and efficient maintenance performance measurement (MPM) system. Incorporating different aspects of traditional literature and considering various frameworks on the subject, it examines the auditing process as well as the use and development of maintenance metrics. It identifies different frameworks and models showcasing how MPM systems should be implemented as well as the values that are created when different frameworks are used. The book presents performance indicators within a framework that classifies and sorts according to functional and hierarchical aspects. It introduces techniques that can help determine the right set of performance indicators. It also outlines a process that combines both numerical indicators with the classical result of massive questionnaires successfully incorporating both the quantitative and qualitative aspects of maintenance performance. In addition, the author provides examples of MPM frameworks that are used in organizations with condition-based, vibration-based, and reliability-centered maintenance. A useful handbook for students and maintenance professionals, this book provides readers with an understanding of how to Align the organizational strategy to the strategies of the maintenance function Link the maintenance performance measures to the different hierarchies of the organization and establish effective communication between them Translate the MPIs at operational level to the corporate level (to create value for the whole organization and its customers) Identify the weaknesses and strengths of the implemented maintenance strategy Maintenance Audits Handbook: A Performance Measurement Framework provides readers with a sound foundation for developing and measuring a comprehensive maintenance improvement strategy using qualitative and quantitative data, and serves as an ideal resource for maintenance/mechanical engineers, maintenance/performance/business/production managers and industry professionals involved in maintenance.

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Increased environmental consciousness within the scientific community has spurred the search for environmentally friendly processes as alternatives to conventional organic solvents. In the past two decades, numerous advances—including the use of ionic liquids—have made it possible to develop substitutes for some toxic solvents. Ionic liquids are widely recognized as suitable for use in organic reactions and can also improve the control of product distribution, enhanced reactivity, ease of product recovery, catalyst immobilization, and recycling.Environmentally Friendly Syntheses Using Ionic Liquids presents the latest developments in the field. It also reviews the latest applications in a wide range of fields including biotechnology, nuclear science, medicine, pharmaceuticals, environmental science, and organic and inorganic chemistry—all from the standpoint of green sustainable chemistry.Growing interest in the field of ionic liquids will define newer and unexplored areas of applications, expanding possible use of these environmentally friendly chemicals. The information presented in this book will undoubtedly help motivate readers to further explore the field.

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Nutrition and infection are often at a crossroads, interacting with each other and influencing human health. Infection is a major health problem and nutritional deficiency plays a significant role in increasing the risk of infection. Nutrition–Infection Interactions and Impacts on Human Health presents state-of-the-art evidence on nutrition–infection interactions and their impact on health and disease. The book explores a wide range of topics including the effects of infection on nutrition—a common occurrence in the developing world—and nutrient–infection interactions for specific infections including HIV, TB, malaria, and parasitic infections. These are reviewed with a special emphasis on nutritional interventions. Also covered is the role of the gastrointestinal tract and its influence on nutrition, focusing on the human gastrointestinal microbiota, enteric syndromes, probiotics, and immunonutrients. The book discusses infection–nutrition interactions in special age groups such as children, adolescents, and the elderly. It also reviews emerging nutritional and anti-infective strategies with an emphasis on future research directions. The book is useful for epidemiologists, nutritionists, and health care staff caring for patients. The book’s broad scope allows for its applicability to both the developed and the developing world.

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Shallow water marine molluscan faunas are distributed in a pattern of distinct, geographically definable areas. This makes mollusks ideal for studying the distribution of organisms in the marine environment and the processes and patterns that control their evolution. Biogeography and Biodiversity of Western Atlantic Mollusks is the first book to use quantitative methodologies to define marine molluscan biogeographical patterns. It traces the historical development of these patterns for the subtropical and tropical western Atlantic. The book discusses the multistage process of evolving new taxa caused by eustatic fluctuations, ecological stress, and evolutionary selection. Drawing on his decades of intensive field work, the author defines three western Atlantic molluscan provinces and 15 subprovinces based on his Provincial Combined Index, a modern refinement of Valentine’s 50% rule. The faunal provinces—Carolinian, Caribbean, and Brazilian—are discussed in detail. The text defines the physical aspects of the provinces using quantitative data, with water temperature as the primary parameter. It discusses the details of the 15 subprovinces—geographically definable faunal subdivisions—as well as provinciatones, transition zones of provincial overlap. The author’s algorithms demonstrate that the bulk of the molluscan biodiversity is concentrated in 40 separate centers of speciation, ranging from Cape Hatteras, North Carolina, south to Argentina. Many of these evolutionary hotspots reside on remote archipelagos and offshore banks as well as within areas of provincial overlap. The text describes some of the more exotic and poorly known areas and presents maps and color photographs of characteristic habitats, index species, and live animals, including over 400 species of rare and seldom seen shells.

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One of the biggest challenges faced in medical research had been to create accurate and relevant models of human disease. A number of good animal models have been developed to understand the pathophysiology. However, not all of them reflect the human disorder, a classic case being Usher’s syndrome where the mutant mice do not have the same visual and auditory defects that patients face. There are others which have been even more difficult to model due to the multi-factorial nature of the condition and due to lack of discovery of a single causative gene such as age-related macular degeneration or Alzheimer’s syndrome. Thus a more relevant and accurate system will allow us to make better predictions on relevant therapeutic approaches.The discovery of human pluripotent stem cells in 1998 followed by the technological advances to reprogram somatic cells to pluripotent-stem cell-like cells in 2006 has completely revolutionized the way we can now think about modelling human development and disease. This now coupled with genome editing technologies such as TALENS and CRISPRs have now set us up to develop in vitro models both 2D as well as 3D organoids, which can more precisely reflect the disease in the patients. These combinatorial technologies are already providing us with better tools and therapeutics in drug discovery or gene therapy. This book summarizes both the technological advances in the field of generation of patient specific lines as well as various gene editing approaches followed by its applicability in various systems. The book will serve as a reference for the current state of the field as it: -Provides a comprehensive overview of the status of the field of patients derived induced pluripotent stem cells.-Describes the use of cardiac cells as a main featured component within the book.-Examines drug toxicity analysis as a working example throughout the book.

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Manufacturing companies work endlessly to make process improvements, yet they are often hard to implement and even harder to sustain. The reason: companies often stumble when communicating why the methodologies are being used and how to sustain the improvements. Communication for Continuous Improvement Projects demonstrates how to communicate change, create confidence in the new processes, and empower employees. It shows how to be an effective change agent by utilizing tools that make sense while being competitive in the business market.The book explores how the proper tools, communication, and management make the Lean Six Sigma methodologies work. It includes a Continuous Improvement Toolkit that is an easy reference for what tool to use and when and how to effectively teach the tools to employees who are not necessarily engineers. Communicating these tools is the most difficult part of using the tools. The author details the implementation of the actual tools that create confidence and explains Lean Six Sigma in a way that will make employees want to jump on board.Result-driven decisions can be made from the methodologies described in this book, making processes quantifiably better with sustainable results. Extensive and informative, the book takes the guesswork out of the art of continuous improvement through communication.

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Combining the two statistical techniques of network sampling and adaptive sampling, this book illustrates the advantages of using them in tandem to effectively capture sparsely located elements in unknown pockets. It shows how network sampling is a reliable guide in capturing inaccessible entities through linked auxiliaries. The text also explores how adaptive sampling is strengthened in information content through subsidiary sampling with devices to mitigate unmanageable expanding sample sizes. Empirical data illustrates the applicability of both methods.

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Established Deterministic Investment Appraisal versus Uncertainty in InvestmentWhen it comes to investing in an infrastructure project, the conventional approach is to evaluate risk through a deterministic approach. Infrastructure Investment: An Engineering Perspective, however, takes on uncertainty in investment. Of interest to engineering consultants, government departments, financial institutions, or anyone involved in investment in infrastructure, this text provides the necessary tools for the analysis and appraisal of investment in infrastructure and other assets with uncertain futures. It factors in the finance and engineering of assets such as roads, buildings, bridges, dams, pipelines, railways, ports, seawalls, wastewater treatment facilities, and addresses future demand, operating costs, maintenance costs, and other lifetime and investment parameters in both financial and non-financial terms. It considers the impact of climate change and the possible use of adaptive and flexible solutions capable of responding to changed futures, as well as how such uncertainty affects the future performance of these investments. The book also incorporates illustrated case studies and Markov chains to model an investment.A pivotal work containing 11 chapters, this text provides: An original contribution to feasibility analysis under uncertainty A systematic and ordered treatment of capital investment in infrastructure A structured flow, from a systematic treatment of conventional deterministic approaches through to a complete treatment incorporating uncertainty Infrastructure Investment: An Engineering Perspective details investment analysis in the presence of uncertainty, and is beneficial to students, academics, and practitioners dealing with decision

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Electrochemically Enabled Sustainability: Devices, Materials and Mechanisms for Energy Conversion covers topics related to current research in electrochemical power sources, highlighting some of the latest concepts in electrochemical conversion for sustainability. The book examines the most recent and innovative technologies employed in battery and fuel cell technology. It introduces the fundamental concepts applied to these electrochemical power sources and provides in-depth discussion on the materials, design, and performance of these devices.Written by internationally acclaimed experts, the chapters illustrate how key technologies for sustainability are enabled by electrochemical conversion. Topics include the reduction of carbon dioxide to resolve issues of carbon capture, energy storage, and generation of portable fuel; turning waste into energy using microbial fuel cells; the promise of vanadium redox flow batteries for massive energy storage; and improved performance of hybrid devices. The book addresses numerous aspects of lithium-type batteries for vehicle propulsion and energy storage, presenting a broad range of lithium batteries, and considering nano-structuring issues, layered-structure materials, and hierarchical structure.This book provides timely coverage of critical issues in emerging and conventional technologies, presenting a wide range of electrochemical devices, related materials, and operation mechanisms. It stimulates an appreciation for the novelty of these electrochemical power sources and offers a projection of future integration of these devices in practice.

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Starting from the preliminaries and ending with live examples, Modern Survey Sampling details what a sample can communicate about an unknowable aggregate in a real situation. The author lucidly develops and presents numerous approaches. He details recent developments and explores fresh and unseen problems, hitting upon possible solutions. The text covers current research output in a student-friendly manner with attractive illustrations. It introduces sampling and discusses how to select a sample for which a selection-probability is specified to prescribe its performance characteristics. The author then explains how to examine samples with varying probabilities to derive profits. He then examines how to use partial segments to make reasonable guesses about a sample’s behavior and assess the elements of discrepancies. Including case studies, exercises, and solutions, the book highlights special survey techniques needed to capture trustworthy data and put it to intelligent use. It then discusses the model-assisted approach and network sampling, before moving on to speculating about random processes. The author draws on his extensive teaching experience to create a textbook that gives your students a thorough grounding in the technologies of survey sampling and modeling and also provides you with the tools to teach them.

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With an estimated 70 percent of new projects failing to add value to the organization, reducing project failure rate represents one of the biggest improvement opportunities available today. This book highlights proven approaches designed to separate the successful projects from the potential losers before the projects are started. This represents huge savings in manpower, money, and time. The book shows you how to reduce project cycle time and apply resources effectively to maximize results and project success rates. Effective Portfolio Management Systems provides a roadmap for the implementation of an organizational Portfolio Project Management (PPM) system and a model for driving sustainable change. It takes you through the complete project/program management cycle—from the submittal of the proposed projects to the management of their implementation. To do this, the authors present an effective, proven, four-phase Organizational Portfolio Management (OPM) system: Phase I: Developing the Organizational Portfolio involves selecting the right mix of projects/programs based upon resource limitations and risks involved. Phase II: Creating the OPM System Implementation Plan is the development of a plan to minimize the resources consumed, reduce cycle time, and increase the ability of the projects to meet their projected value-added content to the organization. Phase III: Implementing the OPM System focuses on the complexity of managing an Organizational Portfolio and keeping it aligned with the organization’s goals and objectives. This phase provides a roadmap for the implementation of an organizational PPM system, including sample plans and PMO Implementation/Management Templates. Phase IV: Practical Applications of Project Change Management within the OPM System focuses on overcoming the difficulties related to the continuous changing environment and project requirements that are encountered as projects are developed and implemented in today’s demanding conditions. This phase provides guidelines for effectively enrolling, communicating with, and training the individuals who are impacted by the project/program to effectively drive sustainable change. At first glance, an OPM system may look like increased bureaucracy. However, when it results in a 20-percent increase in the percentage of projects that are successful, it really turns out to be one of the best resources an organization can invest in to ensure profitability and long-term sustainable results.

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The use of the chemical modification of proteins has evolved over the past 80 years, benefiting from advances in analytical, physical, and organic chemistry. Over the past 30 years, the use of chemical reagents to modify proteins has been crucial in determining the function and structure of purified proteins. This groundbreaking work is part of the foundation of emerging disciplines of proteomics, chemical biology, structure biology, and chemical proteomics.Chemical Reagents for Protein Modification, Fourth Edition provides a comprehensive review of reagents used for the chemical modification of proteins, representing a major revision of the work presented in previous editions. The completely updated Fourth Edition is substantially larger and includes five new chapters: Alkylating Agents Acylating Agents Nitration and Nitrosylation Oxidation Modification of Proteins with Reducing Agents There is greatly increased coverage of the chemical modification of cysteine, which is critical for bioconjugate synthesis. The chapter on reduction also provides information necessary for bioconjugate synthesis as well as for the processing of inclusion bodies. The book places emphasis on conditions that affect the specificity of the chemical modification of proteins, such as solvent and temperature. The format has been markedly revised, presenting information based on the chemical nature of the modifying material and on the amino acid residue modified. This new version has increased significance to biopharmaceuticals. Much of the information is in tabular form, which enables the rapid location of cited material.

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The current drug trafficking crisis between the US and Mexico is a "perfect storm" that has caused deaths, disappearances, and widespread fear of violence and insecurity in the border area between these two countries. Current US drug control policies with Mexico are based on a militarized system of border control and characterized by domestic gridlock over drug control and immigration reform. However, because drug trafficking and other underlying issues have both domestic and international consequences, they cannot be resolved unless both countries work together. Using the "Narcotrafico" Threat to Build Public Administration Capacity between the US and Mexico explores how they can do exactly that.Co-edited by two public administration scholars from Mexico and the US and comprising chapters by 18 other experts from Mexico, Canada, and the US, the book demonstrates how the current situation of drug trafficking and violence, on top of the other existing perceptions and conditions, creates a real opportunity for the US to build relationships with its Mexican counterparts at state, local, national, and NGO levels. With chapters written by leading experts working in a broad spectrum of international and domestic US-Mexico policy issues, the book covers immigration, drug flow and conflict, gun-running, money laundering, education and economic and community development in both countries.. Only by supporting bi-national drug policies based on mutual understanding of the border as something that both separates and unites the US and Mexico will it be possible to develop cooperative policies that can lead from militarization to regularization of the US-Mexico border. Twenty years after the signing of NAFTA (North American Free Trade Agreement) in 1994, it is time to recognize the link between effective drug control policies and the emergence of North America as a regional economic, social, and political powerhouse capable of successfully competing with the European Union, China, and other emerging regions in our increasingly globalized world, this book offers concrete, long-term solutions for building cooperative and shared public administrative capacity on both sides of the border.

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The book offers information about the iOS platform. It explains the use of OpenGL ES for 2D/3D graphics and OpenAL for sound, both of which are recommended for game performance on the iOS platform. It covers new APIs such as the GLKit, GameKit, and Box2D Physics Engine.

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Estimate and Interpret Results from Ordered Regression ModelsOrdered Regression Models: Parallel, Partial, and Non-Parallel Alternatives presents regression models for ordinal outcomes, which are variables that have ordered categories but unknown spacing between the categories. The book provides comprehensive coverage of the three major classes of ordered regression models (cumulative, stage, and adjacent) as well as variations based on the application of the parallel regression assumption.The authors first introduce the three "parallel" ordered regression models before covering unconstrained partial, constrained partial, and nonparallel models. They then review existing tests for the parallel regression assumption, propose new variations of several tests, and discuss important practical concerns related to tests of the parallel regression assumption. The book also describes extensions of ordered regression models, including heterogeneous choice models, multilevel ordered models, and the Bayesian approach to ordered regression models. Some chapters include brief examples using Stata and R.This book offers a conceptual framework for understanding ordered regression models based on the probability of interest and the application of the parallel regression assumption. It demonstrates the usefulness of numerous modeling alternatives, showing you how to select the most appropriate model given the type of ordinal outcome and restrictiveness of the parallel assumption for each variable.Web ResourceMore detailed examples are available on a supplementary website. The site also contains JAGS, R, and Stata codes to estimate the models along with syntax to reproduce the results.

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There is no shortage of incentives to study and reduce poverty in our societies. Poverty is studied in economics and political sciences, and population surveys are an important source of information about it. The design and analysis of such surveys is principally a statistical subject matter and the computer is essential for their data compilation and processing.Focusing on The European Union Statistics on Income and Living Conditions (EU-SILC), a program of annual national surveys which collect data related to poverty and social exclusion, Statistical Studies of Income, Poverty and Inequality in Europe: Computing and Graphics in R presents a set of statistical analyses pertinent to the general goals of EU-SILC. The contents of the volume are biased toward computing and statistics, with reduced attention to economics, political and other social sciences. The emphasis is on methods and procedures as opposed to results, because the data from annual surveys made available since publication and in the near future will degrade the novelty of the data used and the results derived in this volume.The aim of this volume is not to propose specific methods of analysis, but to open up the analytical agenda and address the aspects of the key definitions in the subject of poverty assessment that entail nontrivial elements of arbitrariness. The presented methods do not exhaust the range of analyses suitable for EU-SILC, but will stimulate the search for new methods and adaptation of established methods that cater to the identified purposes.

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A critical and often overlooked aspect of preventing medical device recalls is the ability to implement systems thinking. Although systems thinking won’t prevent every mistake, it remains one of the most effective tools for evaluating hidden risks and discovering robust solutions for eliminating those risks.Based on the author’s extensive experience in the medical device, aerospace, and manufacturing engineering industries, Preventing Medical Device Recalls presents a detailed structure for systems thinking that can help to prevent costly device recalls. Based on Dr. W. Edwards Deming’s System of Profound Knowledge, this structure can help medical device designers and manufacturers exceed their customers’ expectations for quality and safety.This book is among the first to demonstrate how to control safety risks—from specifications all the way through to safely retiring products without harm to the environment. Supplying an accessible overview of medical device requirements and the science of safety, it explains why risk analysis must start with product specification and continue throughout the product life cycle.Covering paradigms for proactive thinking and doing, the text details methods that readers can implement during the specification writing, product design, and product development phases to prevent recalls. It also includes numerous examples from the author’s experience in the medical device, consumer, and aerospace industries.Even in healthcare, where compliance with standards is at its highest level, more patients die from medical mistakes each week than would be involved in a jumbo jet crash. With coverage that includes risk assessment and risk management, this book provides you with an understanding of how mishaps happen so you can account for unexpected events and design devices that are free of costly recalls.

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A discussion of the basic reliability concepts and models, Reliability Models for Engineers and Scientists demystifies modern mathematical reliability models. Requiring very little mathematical background on the reader’s part, this concise book introduces the models by focusing on their physical meaning and the supporting data; it then goes on to provide a wide scope of possible applications. The book also introduces a new concept of the Gini-type index, which when applied to aging/rejuvenating components (nonrepairable systems) can measure how different a given aging/rejuvenation distribution is compared to the exponential distribution. A similar index is then applied to aging/rejuvenating repairable systems, creating a bridge between the concepts. The chapters discuss models used in reliability, risk analysis, physics of failure, fracture mechanics, biological, pharmaceutical, and medical studies. They comprise an up-to-date, concise, and informative resource on reliability models, which does not require any special mathematical background.

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Thermal-hydraulic instability can potentially impair thermal reliability of reactor cores or other power equipment components. Thus it is important to address stability issues in power equipment associated with thermal and nuclear installations, particularly in thermal nuclear power plants, chemical and petroleum industries, space technology, and radio, electronic, and computer cooling systems. Coolant Flow Instabilities in Power Equipment synthesizes results from instability investigations around the world, presenting an analysis and generalization of the published technical literature.The authors include individual examples on flow stability in various types of equipment, including boilers, reactors, steam generators, condensers, heat exchangers, turbines, pumps, deaerators, bubblers, and pipelines. They also present information that has not been widely available until recently, such as thermal-acoustic instability, flow instability with supercritical parameters, and single-phase coolant flow static instability. The material described in this book is derived from vast amounts of experimental data from thermal-physical test facilities and full-scale installations. It is presented in a manner accessible to readers without advanced mathematical backgrounds.Particular attention has been paid to oscillatory (low-frequency and thermal-acoustic) and static thermal-hydraulic coolant flow instability. In addition, the physical mechanism of instability has been considered in detail. This book provides knowledge of the various types of flow instability, the equipment where this instability can manifest, and the ensuing consequences, as well as makes recommendations concerning possible removal or mitigation of these consequences. The authors provide this information as a useful reference for readers to facilitate the enhanced safety of modern power equipment through qualitative evaluation of design and flow parameters and subsequent selection of the optimal means for increasing flow stability.

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Addressing the beliefs and attitudes that can be detrimental to your organization’s competitiveness, Popular Manufacturing Myths: Eliminating Widely Held Beliefs That Reduce Competitiveness offers time-tested insight into the most common myths encountered in manufacturing environments. It classifies these myths into management myths, shop floor myths, and if appropriate, shared management and shop floor myths.Explaining the reasons why these deeply ingrained beliefs exist, the book outlines remedies that can help to quickly dispel them within your organization. It presents case studies that examine these myths and includes numerous real-world examples that outline simple, yet effective, solutions. Some of the myths dispelled in this book include: Increasing line speed always decreases quality and creates more scrap Reducing the cost of raw materials will decrease the cost of manufacturing Increased inspection will boost quality If it is successful in R&D, it will be successful in production Process problems can only be solved by changing one process parameter at a time Covering the basics of data collection tools, techniques, and analysis, the text offers simple methods to structure your data to assist in communicating clear and logical conclusions across the organization. The author keeps the arithmetic and statistics to a minimum, so readers only require a basic understanding of averaging and normal variation. However, for those who wish to understand a little bit more about a particular concept, technique, tool, or procedure, the book includes an addendum chapter with more detailed explanations and sample calculations.

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Addresses the Challenges Associated with System-on-Chip Integration Network-on-Chip: The Next Generation of System-on-Chip Integration examines the current issues restricting chip-on-chip communication efficiency, and explores Network-on-chip (NoC), a promising alternative that equips designers with the capability to produce a scalable, reusable, and high-performance communication backbone by allowing for the integration of a large number of cores on a single system-on-chip (SoC). This book provides a basic overview of topics associated with NoC-based design: communication infrastructure design, communication methodology, evaluation framework, and mapping of applications onto NoC. It details the design and evaluation of different proposed NoC structures, low-power techniques, signal integrity and reliability issues, application mapping, testing, and future trends.Utilizing examples of chips that have been implemented in industry and academia, this text presents the full architectural design of components verified through implementation in industrial CAD tools. It describes NoC research and developments, incorporates theoretical proofs strengthening the analysis procedures, and includes algorithms used in NoC design and synthesis. In addition, it considers other upcoming NoC issues, such as low-power NoC design, signal integrity issues, NoC testing, reconfiguration, synthesis, and 3-D NoC design. This text comprises 12 chapters and covers: The evolution of NoC from SoC—its research and developmental challenges NoC protocols, elaborating flow control, available network topologies, routing mechanisms, fault tolerance, quality-of-service support, and the design of network interfaces The router design strategies followed in NoCs The evaluation mechanism of NoC architectures The application mapping strategies followed in NoCs Low-power design techniques specifically followed in NoCs The signal integrity and reliability issues of NoC The details of NoC testing strategies reported so far The problem of synthesizing application-specific NoCs Reconfigurable NoC design issues Direction of future research and development in the field of NoC Network-on-Chip: The Next Generation of System-on-Chip Integration covers the basic topics, technology, and future trends relevant to NoC-based design, and can be used by engineers, students, and researchers and other industry professionals interested in computer architecture, embedded systems, and parallel/distributed systems.

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Complex Systems is a new field of science studying how parts of a system give rise to the collective behaviors of the system, and how the system interacts with its environment. This book examines the complex systems involved in environmental sustainability, and examines the technologies involved to help mitigate human impacts, such as renewable energy, desalination, carbon capture, recycling, etc. It considers the relationships and balance between environmental engineering and science, economics, and human activity, with regard to sustainability.

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