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Dementia represents a major public health challenge for the world with over 100 million people likely to be affected by 2050. A large body of professionals is active in diagnosing, treating, and caring for people with dementia, and research is expanding. Many of these specialists find it hard to keep up to date in all aspects of dementia. This book helps solve that problem. The new edition has been updated and revised to reflect recent advances in this fast-moving field.

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Thermodynamic data of polymer solutions are paramount for industrial and laboratory processes. These data also serve to understand the physical behavior of polymer solutions, study intermolecular interactions, and gain insights into the molecular nature of mixtures. Nearly a decade has passed since the release of a similar CRC Handbook and since then a large amount of new experimental data have been published, which is now compiled in this book.The CRC Handbook of Phase Equilibria and Thermodynamic Data of Polymer Solutions at Elevated Pressures features nearly 500 newly published references containing approximately 175 new vapor-liquid equilibrium data sets, 25 new liquid-liquid equilibrium data sets, 540 new high-pressure fluid phase equilibrium data sets, 60 new data sets describing PVT properties of polymers, and 20 new data sets with densities or excess volumes. The book is a valuable resource for researchers, specialists, and engineers working in the fields of polymer science, physical chemistry, chemical engineering, materials science, biological science and technology, and those developing computerized predictive packages.

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Software analysis patterns play an important role in reducing the overall cost and compressing the time of software project lifecycles. However, building reusable and stable software analysis patterns is still considered a major and delicate challenge. This book proposes a novel concept for building analysis patterns based on software stability and is a modern approach for building stable, highly reusable, and widely applicable analysis patterns. The book also aims to promote better understanding of problem spaces and discusses how to focus requirements analysis accurately. It demonstrates a new approach to discovering and creating stable analysis patterns (SAPs). This book presents a pragmatic approach to understanding problem domains, utilizing SAPs for any field of knowledge, and modeling stable software systems, components, and frameworks. It helps readers attain the basic knowledge that is needed to analyze and extract analysis patterns from any domain of interest. Readers also learn to master methods to document patterns in an effective, easy, and comprehensible manner.Bringing significant contributions to the field of computing, this book is a unique and comprehensive reference manual on SAPs. It provides insight on handling the understanding of problem spaces and supplies methods and processes to analyze user requirements accurately as well as ways to use SAPs in building myriad cost-effective and highly maintainable systems. The book also shows how to link SAPs to the design phase thereby ensuring a smooth transition between analysis and design.

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Without Lean leaders, there can be no Lean. If an organization wants to be Lean, its leaders must lead using Lean principles. Put another way, until the top of your organization fully embraces Lean, the rest of your organization will never be Lean.The Lean Leader: A Personal Journey of Transformation uses a compelling novel format to tackle the nuts and bolts of leading a Lean transformation. Readers follow along as the characters face real crises and what seem to be unreasonable deadlines. As the story progresses, readers will see how the main character, Don, and his colleagues transform from being "command and control" autocrats—those who make decisions and bark orders—to more Socratic coaches and mentors.As Don and his staff come to realize that the folks they employ are the real experts in the processes they control, you will learn why it behooves you to do more asking than telling. You will come to realize that a leader’s greatest skill must be in coaching great performance from their people. You will also witness the difference between managing and leading.After reading this book, you will understand why it’s so important to shed the decision-making tasks that have cluttered your days, and how to delegate those decisions to employees who are closer to the action. You will learn how important it is to look over the horizon to identify upcoming challenges, define and communicate new courses of action, and compel others to follow.Most importantly, you will learn exactly what it takes to lead a Lean organization that thrives socially, as well as financially.

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Tribosystem Analysis: A Practical Approach to the Diagnosis of Wear Problems provides a systematic framework for conducting root cause analyses and categorizing various types of wear. Designed specifically for engineers without formal training in tribology, this book: Describes a number of direct and indirect methods for detecting and quantifying wear problems Surveys different microscopy techniques, including those for light optics, electron optics, and acoustic imaging Discusses the selection of wear and friction test methods, both standard and custom, identifying possible pitfalls for misuse Presents practical examples involving complex materials and environments, such as those with variable loads and operating conditions Uses universally accepted terminology to create consistency along with the potential to recognize similar problems and apply comparable solutions Complete with checklists to ensure the right questions are asked during diagnosis, Tribosystem Analysis: A Practical Approach to the Diagnosis of Wear Problems offers pragmatic guidance for defining wear problems in the context of the materials and their surroundings.

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HPC is used to solve a number of complex questions in computational and data-intensive sciences. These questions include the simulation and modeling of physical phenomena, such as climate change, energy production, drug design, global security, and materials design; the analysis of large data sets such as those in genome sequencing, astronomical observation, and cybersecurity; and the intricate design of engineered products, such as airplanes and automobiles.This second volume of Contemporary High Performance Computing: From Petascale toward Exascale continues to document international HPC ecosystems, including the sponsors and sites that host them. Each chapter is punctuated with a site's flagship system and: Presents highlights of applications, workloads, and benchmarks Describes hardware architectures, system software, and programming systems Explores storage, visualization, and analytics Examines the data center/facility as well as system statistics Featuring pictures of buildings and systems in production, floorplans, and many block diagrams and charts to illustrate system design and performance, Contemporary High Performance Computing: From Petascale toward Exascale, Volume Two delivers a detailed snapshot of the rich history of practice in modern HPC. This book provides a valuable reference for researchers in HPC and computational science.

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Doody’s Core Title® 2002Sheep Medicine, Second Edition describes key sheep diseases encountered in general practice along with their diagnoses, treatment, prognoses, control, and, where appropriate, post-mortem features. The book is divided into chapters covering each body system. Each chapter of this completely revised and updated book opens with a recommended approach to clinical examination of the featured body system, rather than simply providing a listing of disorders and diseases. The book also guides readers through all stages of the disease process highlighting the critical clinical features important in the diagnosis. Ancillary tests available to veterinary practitioners are detailed, emphasising their practical applications and cost limitations. Several self-assessment exercises featuring typical clinical cases affecting each body system are collected in a revision chapter at the end of the book. Diseases and disorders are included with the common differential diagnoses followed by the specific diagnosis and recommended treatment(s). The book is invaluable to veterinarians in practice and training, animal scientists and agricultural advisors, and scientists interested in animal welfare.

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Theoretical and practical interests in additive manufacturing (3D printing) are growing rapidly. Engineers and engineering companies now use 3D printing to make prototypes of products before going for full production. In an educational setting faculty, researchers, and students leverage 3D printing to enhance project-related products. Additive Manufacturing Handbook focuses on product design for the defense industry, which affects virtually every other industry. Thus, the handbook provides a wide range of benefits to all segments of business, industry, and government. Manufacturing has undergone a major advancement and technology shift in recent years.

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This book summarizes the knowledge in the field of methods to identify signatures of natural selection. A number of mathematical models and methods have been designed to identify the fingerprints of natural selection on genes and genomes. Such methods are provided in a simple and direct way so that students of different disciplines can navigate through molecular fitness landscapes using complex methods with a basic knowledge on bioinformatics. A collection of the main methods to detect selection in protein-coding genes and amino acid sequences is given at different levels of complexity, from nucleotides to proteins and molecular networks. The importance of identifying natural selection in genes and genomes through the methods described in this book transcends the bioinformatics and computational biology fields, presenting applications for experimental biologists in a straightforward and understandable way.

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Light Scattering Technology for Food Property, Quality and Safety Assessment discusses the development and application of various light scattering techniques for measuring the structural and rheological properties of food, evaluating composition and quality attributes, and detecting pathogens in food. The first four chapters cover basic concepts, principles, theories, and modeling of light transfer in food and biological materials. Chapters 5 and 6 describe parameter estimation methods and basic techniques for determining optical absorption and scattering properties of food products.Chapter 7 discusses the spatially-resolved measurement technique for determining the optical properties of food and biological materials, whereas Chapter 8 focuses on the time-resolved spectroscopic technique for measuring optical properties and quality or maturity of horticultural products. Chapter 9 examines practical light scattering techniques for nondestructive quality assessment of fruits and vegetables. Chapter 10 presents the theory of light transfer in meat muscle and the measurement of optical properties for determining the postmortem condition and textural properties of muscle foods and meat analogs.Chapter 11 covers the applications of spatially-resolved light scattering techniques for assessing quality and safety of animal products. Chapter 12 looks into light scattering for milk and dairy processing. Chapter 13 examines the applications of dynamic light scattering for measuring the microstructure and rheological properties of food. Chapter 14 shows the applications of a biospeckle technique for assessing the quality and condition of fruits and vegetables. Chapter 15 provides a detailed description of Raman scattering spectroscopic and imaging techniques in food quality and safety assessment. Chapter 16, the final chapter, focuses on applications of light scattering techniques for the detection of food-borne pathogens.

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Human Computer Interface Technologies for the Motor Impaired examines both the technical and social aspects of human computer interface (HCI). Written by world-class academic experts committed to improving HCI technologies for people with disabilities, this all-inclusive book explores the latest research, and offers insight into the current limitations of this field. It introduces the concept of HCI, identifies and describes the fundamentals associated with a specific technology of HCI, and provides examples for each. It also lists and highlights the different modalities (video, speech, mechanical, myoelectric, electro-oculogram, and brain-waves) that are available, and discusses their relevant applications. Easily and readily understood by researchers, engineers, clinicians, and the common layperson, the book describes a number of HCI technologies ranging from simple modification of the computer mouse and joystick to a brain–computer interface (BCI) that uses the electrical recording of the brain activity of the user. The text includes photographs or illustrations for each device, as well as references at the end of each chapter for further study.In addition, this book: Describes the mechanical sensors that are used as an interface to control a computer or screen for the aged and disabled Discusses the BCI using brain waves recorded by noninvasive electrodes to recognize the command from the user Presents the myoelectric interface for controlling devices such as the prosthetic/robotic hand Explains the technology of tracking the eye gaze using video Provides the fundamentals of voice recognition technologies for computer and machine control applications Examines a secure and voiceless method for the recognition of speech-based commands using video of lip movement Human Computer Interface Technologies for the Motor Impaired considers possible applications, discusses limitations, and presents the current research taking place in the field of HCI. Dedicated to enhancing the lives of people living with disabilities, this book aids professionals in biomedical, electronics, and computer engineering, and serves as a resource for anyone interested in the developing applications of HCI.

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Intraperitoneal Cancer Therapy: Principles and Practice is one of the first books to combine the latest clinical developments in the treatment of patients with peritoneal surface disease and the scientific principles that underlie the concept of intraperitoneal cancer therapy. The book covers basic concepts such as anatomy, physiology, pharmacology, and mathematical models of drug transport as well as practical clinical applications, highlighted with results from clinical trials and promising novel preclinical developments.The book is a state-of-the-art reference for surgical and medical oncologists interested in the treatment of carcinomatosis. It also establishes and promotes basic and translational research interest in the field of intraperitoneal drug delivery, which has the potential to improve the outcome for this dreaded condition. Edited by two renowned surgical oncologists, it represents the definitive reference in the field of intraperitoneal cancer therapy.

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How Can Polymers Constructed From Living Organisms Help Eliminate the Disposal Issue?A unique category of materials called biodegradable polymers could help remedy a growing environmental concern. Biodegradable Polymeric Nanocomposites: Advances in Biomedical Applications considers the potential of biodegradable polymers for use in biomedical applications that include drug delivery, biosensors, and tissue engineering. Since biomaterials perform on a time-limited function and are designed to disappear from the body after use, the development of biopolymers could greatly reduce and eliminate the need for plastic products, most specifically those used in biomedical applications.Highlights Biomaterials and the Design and Application of BiomaterialsUtilizing expert research contributors from around the world, this book considers the benefits and limitations of a variety of biomaterials, such as biopolymers, ceramics, biodegradable nanocomposites, and natural products–based biomaterials. It explores the bio-nano-interface; the interaction between nanoparticles and biomaterials, explains the basic concepts and methods of biodegradable nanocomposites (BNCs), and highlights recent developments in polymer-based bionanocomposites. The book provides an overview of degradation properties and the mechanical properties of biodegradable polymers. It also breaks down the mechanical properties and biocompatibility of starch-based polymers, and outlines distinct advantages (biodegradability and nontoxicity) that make them suitable as medical polymer materials. In addition, it highlights the FDA-approved biodegradable polyester family and focuses on the state-of-the-art recent advancements in drug-delivery devices. Biodegradable Polymeric Nanocomposites: Advances in Biomedical Applications provides current knowledge on biopolymers, examines recent developments and trends, and considers future applications of polymers. Featuring the work of highly-qualified international researchers, this book addresses applications relevant to polymer and material science, as well as material, biomedical, and chemical engineering, and is of specific interest to polymer science engineers.

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The second edition of Endocrine Surgery is a comprehensive update of the previous edition published in 2003. Edited by three leading authorities in the field of surgical endocrinology, the book encompasses the clinical, imaging, nuclear, molecular, technological and evidence-based principles that are applied in the diagnosis and treatment of all categories of endocrine tumors. Authored by experts from across the globe, this textbook reflects the best international clinical practice and also provides an outstanding educational resource. With full color illustrations throughout, the new edition emphasizes contemporary approaches in successive stages including: pituitary endocrine tumors; pathology and pathophysiology of pulmonary neuroendocrine cells; surgery of endocrine tumors of the lungs and thymus; robotic endocrine surgery; molecular testing of thyroid nodules; pediatric surgery for neuroblastoma and ganglioneuroma; multiple endocrine neoplasia; retroperitoneoscopic adrenalectomy; radionuclide imaging of carcinoid tumors, pancreas and adrenals; serotonin-induced cardiac valvular disease and surgical treatment; multimodal management of primary and metastatic neuroendocrine tumors; pathophysiology and surgery of Type II diabetes; post-bariatric surgery hyperinsulinemic hypoglycemia; and surgical management of metabolic syndrome.Endocrine Surgery 2e provides the clinician with a definitive resource to reach curative outcomes in the treatment of patients with endocrine pituitary, thyroid, and parathyroid entities. Further coverage of broncho-pulmonary, adrenal, pancreatic, and intestinal neoplasia is also included, making this the definitive textbook on the subject.Demetrius Pertsemlidis, MD FACS The Bradley H. Jack Professor of Surgery, Icahn School of Medicine at Mount Sinai, New York, USAWilliam B. Inabnet III, MD FACS Professor of Surgery and Chief, Division of Metabolic, Endocrine and Minimally Invasive Surgery, Icahn School of Medicine at Mount Sinai, New York, USAMichel Gagner, M.D. FRCSC, FACS, FASMBSClinical Professor of surgery, Herbert Wertheim School of Medicine, Florida International University, Miami, FL and Senior consultant, Hôpital du Sacre Coeur, Montreal, Quebec, CanadaPrint Versions of this book also include access to the ebook version.

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Do you ever wonder why size is so important at the scale of nanosystems? Do you want to understand the fundamental principles that govern the properties of nanomaterials? Do you want to establish a foundation for working in the field of nanoscience and nanotechnology? Then this book is written with you in mind.Foundations for Nanoscience and Nanotechnology provides some of the physical chemistry needed to understand why properties of small systems differ both from their constituent molecular entities and from the corresponding bulk matter. This is not a book about nanoscience and nanotechnology, but rather an exposition of basic knowledge required to understand these fields. The collection of topics makes it unique, and these topics include: The concept of quantum confinement and its consequences for electronic behaviour (Part II) The importance of surface thermodynamics for activity and interactions of nanoscale systems (Part III) The need to consider fluctuations as well as mean properties in small systems (Part IV) The interaction of light with matter and specific applications of spectroscopy and microscopy (Part V) This book is written for senior undergraduates or junior graduate students in science or engineering disciplines who wish to learn about or work in the areas of nanoscience and nanotechnology, but who do not have the requisite background in chemistry or physics. It may also be useful as a refresher or summary text for chemistry and physics students since the material is focused on those aspects of quantum mechanics, thermodynamics, and statistical mechanics that specifically relate to the size of objects.

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Error-proofing in the production process of pharmaceuticals isn’t just a matter of good business, it has life-and-death implications for consumers. To that end, the 2013 Drug Quality and Security Act in large part requires new mandates on tracking and tracing chain of custody in the supply chain. Pharmaceutical Supply Chain: Drug Quality and Security Act overviews the new mandate and its implications, including implementation strategies for track-and-trace programs along with presenting a fuller understanding of the mechanics of intergovernmental policies and oversights.The book focuses on the delicate balance between protecting the public through legislation against negligent compounding pharmacies and protecting patients by assuring a supply of needed compounded drugs by not over-regulating the industry. The author discusses lessons learned from the earlier e-pedigree initiatives, the technology advances that enable supply chain security, and how the industry will need to respond to the myriad of threats facing the pharmaceutical drug supply chain and comply with this act. He goes in depth into each segment of the pharmaceutical drug supply chain, describing the industry segment and how it will need to adapt to the new act.By incorporating real-world examples of industry leaders, the book underlines the contributions of individuals who have made a difference through innovations and execution. It also addresses how laws are made, and specifically how the Drug Quality and Security Act was passed by Congress and signed into law. In an industry that is so big, you may feel that you cannot make a difference. This book provides you with key insights on how the forward supply chain process should work and how anyone can make a difference at all levels.

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This book provides a comprehensive collection of the latest information on nanomaterials and nanocomposites. It covers material synthesis, processing, structure characterization, properties and applications. It presents a coherent treatment of how composite properties depend on nanostructure, and covers cutting-edge topics like bionanocomposites for sustainable development. This book summarizes many developments in the field making it an ideal resource for researchers from industry, academia, government and private research institutions.

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Phosphorus is an essential plant nutrient, but global population growth has dramatically reduced the availability of phosphorus fertilizer resources. Despite this scarcity, there remain numerous problems associated with the excessive and inappropriate use of phosphorus leading to non-point source pollution and eutrophication of natural waters. Identifying appropriate systems for managing soil phosphorus and reducing the risks of eutrophication are needed to minimize the environmental risks. This book focuses on the availability and recycling of phosphorus; regulatory and policy issues of sustainable phosphorus use; and water quality management in agroecosystems pertaining to phosphorus. Sections are dedicated to global phosphorus reserves; cycling and pathways of phosphorus; phosphorus in agriculture; human dimensions and policy intervention; and research and development priorities.Phosphorus is a finite but crucial resource and is an essential element to all life. Sub-optimal availability and nutrient imbalance in the root zone can adversely impact plant growth, and the quality of food and feed grown on these soils. However, the proven reserves of phosphorus can hardly be adequate for a few centuries only. Yet, its misuse and mismanagement has caused severe problems of eutrophication of water and pollution of the environment. Thus, judicious management of soil phosphorus is essential. This volume is specifically devoted to availability and recycling of phosphorus, regulatory/policy issues of sustainable use of phosphorus, and management in agroecosystems in the context of maximizing the use efficiency and minimizing the environmental risks of water quality.

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A significant portion of biomedical applications necessitates the establishment of an interface between the cells of the patient and the components of the device. In many cases, such as in implants and engineered tissues, the interaction of the cells with the biomaterial is one of the main determinants of the success of the system. Cell and Material Interface: Advances in Tissue Engineering, Biosensor, Implant, and Imaging Technologies explores this interaction and its control at length scales ranging from the nano to the macro.Featuring contributions from leading molecular biologists, chemists, and material scientists, this authoritative reference: Presents practical examples of cell and material interface-based applications Reflects the interdisciplinary nature of bioengineering, covering topics such as biosensing, immunology, and controlled delivery Explains the role of the cell and material interface in the context of cardiac and skin tissue engineering, nanoparticles, natural polymers, and more Cell and Material Interface: Advances in Tissue Engineering, Biosensor, Implant, and Imaging Technologies addresses concepts essential to biomaterial production methods and cell and material interactions. The book provides a solid starting point for elucidating and exploiting the different aspects of cellular interactions with materials for biomedical engineering.

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Greywater Reuse examines the features and implications of greywater reuse scientifically, quantitatively, and thoroughly.Based on the authors’ extensive studies of treatment facilities in urban and rural environments, development of greywater treatment systems, and research of potential environmental and health risks posed by greywater at different treatment levels, this authoritative text: Describes the chemical, physical, and microbial properties of greywater Covers the treatment and removal of greywater pollutants, providing case studies of common methods Identifies the risks involved in greywater use and proposes regulatory measures to help reduce these risks Reviews the greywater management strategies, policies, and legislation of several different countries Discusses the prevailing public perception and willingness to adopt various uses of greywater Analyzes the economic impact of greywater reuse from both the consumer and national perspectives Greywater Reuse addresses all major aspects related to greywater reuse, making it a valuable resource for a variety of applications.

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Remote Sensing of Impervious Surfaces in Tropical and Subtropical Areas offers a complete and thorough system for using optical and synthetic aperture radar (SAR) remote sensing data for improving impervious surface estimation (ISE). Highlighting tropical and subtropical areas where there is significant cloud occurrence and varying phenology, the book addresses the challenges impacting impervious surfaces in tropical and subtropical zones. It examines the potential for estimating urban impervious surfaces in a rainy and cloudy environment, considers the difficulties encountered when using optical remote sensing in this type of climate, and assesses existing methods employing remote sensing data for accurate ISE in tropical and subtropical regions. Using the results of comparative studies conducted during the four seasons and in six different cities (Guangzhou, Shenzhen, Hong Kong, Mumbai, Sao Paulo, and Cape Town), the authors develop a framework for ISE using optical and SAR image data. They address the advantages and disadvantages of optical and SAR data, consider fusion strategies for combining optical and SAR data, and examine different feature extractions for optical and SAR data. They also detail the limitations of the research, suggest possible topics for future analysis, and cover previous findings on the synergistic use of optical and SAR data. Concentrates on the effect a tropical and subtropical urban climate can have on impervious surface estimation (ISE) Reviews literature on the significance of ISE and the phonological and climatic characteristics of tropical and subtropical regions Describes datasets including satellite data, digital orthophoto data, in situ data, and more Remote Sensing of Impervious Surfaces in Tropical and Subtropical Areas investigates the state of the art in creating new algorithms for digital images processing and remotely sensed images classification, as well as in developing the meteorological modeling of urban heat islands, and the hydrological modeling of surface run-off and urban floods.

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Pests of Fruit Crops: A Colour Handbook, Second Edition provides an up-to-date illustrated account of the various pests of fruit crops throughout Europe, many of which (or their close relatives) are also present in non-European countries. In fact, several pose problems on fruit crops worldwide. This authoritative book focuses on insect and mite pests affecting fruit, hop and nut crops in both temperate and subtropical climates. Pome fruits, stone fruits, cane fruits, strawberries, bush fruits, hops, grapevines, citrus fruits, nuts, figs and olives all receive attention.For ease of reference, this new edition has been significantly rearranged so that, under genera, species of pests are now listed alphabetically, and nomenclature has been updated. The pests, most of which are illustrated, are described, and details are given of their life histories, distribution and status. Damage caused is also indicated. The work is profusely illustrated with over 1,150 superb colour photographs, and is an essential and invaluable source of reference for both professional and lay readers—including extension workers, consultants, scientists, students, fruit growers and private gardeners. To help readers locate information on pests of interest, alternative names for genera and species, and frequently used colloquial names are cross-referenced in the pest index.

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This book is designed to help the busy practitioner develop a differential diagnosis for the otolaryngology problems they encounter in the outpatient, inpatient, or emergency setting. The authors discuss clinical presentations and treatments, complemented by photographs of examinations and procedures to help physicians with diagnosis. The book features concise descriptions and highlights key treatment plans for the most common conditions in otolaryngology. For ease of reference, chapters are organised into five major sections, reflecting the make-up of the specialty: Otology, Rhinology/Skull Base, Laryngology, Head & Neck, Facial Plastics, and Pediatrics.Easy to read and richly illustrated with relevant clinical photographs and diagrams, Otolaryngology: A Color Handbook will be an indispensable reference for otolaryngologists, primary care providers, physician assistants, nurses, and students.

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Processes of Formation of Micro- and Nanodispersed Systems is a comprehensive analysis and presentation of the physical processes and phenomena that lead to the formation of disperse materials. It also details the properties of disperse materials yielded from various processes.Special attention is given to the homogeneous condensation of metal vapours from expanding metal vapours in a vacuum, as well as heterogeneous condensation of metal vapours on solid substrates in the presence of impurities during the formation of disperse condensates. The book also examines flow in thin films, the decay of thin films, and phenomena accompanying the coalescence of disperse particles.Using currently available data, this book compares different methods of producing disperse materials in terms of scale. It also describes several applications of the experimental results it presents, including: Production of composites of nanodisperse metals in an organic matrix Production of metallic powders The potential to produce metallic powders on an industrial scale with the creation of a special plant Fine cleaning of gases contaminated with micro- and nanoparticles, including aerosols such as spray paint Covering and expanding applications of key processes concerning metal vapours, Processes of Formation of Micro- and Nanodispersed Systems is highly valuable to researchers of semiconductors. It provides a single source of detailed and practical information on the processes and phenomena related to the formation of disperse materials. It represents the current state of research and practice in micro- and nanodispersed systems while highlighting paths to advancement in the field.

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There has been enormous growth in the use of medical implants. However, in the case of hip replacement, loosening of metallic prosthesis fixed with polymethylmethylacrylate bone cement has resulted in painstaking revision surgery, which is a major problem for the patient, surgeon, and biomedical technology itself. In fact, global recognition of this problem led to the development of cementless fixation through the novel introduction of a bioactive hydroxyapatite (HAp) coating on biomedical-grade metallic implants. Since then, a wide variety of coating methods have evolved to make the HAp coatings on metallic implants more reliable.Microplasma Sprayed Hydroxyapatite Coatings discusses plasma spraying and other related HAp coating techniques, focusing on the pros and cons of macroplasma sprayed (MAPS)- and microplasma sprayed (MIPS)-HAp coatings. The book begins by explaining what a biomaterial really is, what the frequently used term biocompatibility stands for, and why it is so important for biomaterials to be biocompatible. It then: Examines the structural, chemical, macromechanical, micro/nanomechanical, and tribological properties and residual stress of HAp coatings Evaluates the efficacies under simulated body fluid immersion for MAPS- and MIPS-HAp coatings developed on biomedical implant-grade SS316L substrates Offers a comprehensive survey of state-of-the-art in vivo studies of MIPS-HAp coatings, presenting the results of pioneering research related to bone defect fixation Shedding light on the future scope and possibilities of MIPS-HAp coatings, Microplasma Sprayed Hydroxyapatite Coatings provides a valuable reference for students, researchers, and practitioners of biomedical engineering and materials science.

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The accurate design of earth–space systems requires a comprehensive understanding of the various propagation media and phenomena that differ depending on frequencies and types of applications. The choice of the relevant channel models is crucial in the design process and constitutes a key step in performance evaluation and testing of earth–space systems. The subject of this book is built around the two characteristic cases of satellite systems: fixed satellites and mobile satellite systems.Radio Wave Propagation and Channel Modeling for Earth–Space Systems discusses the state of the art in channel modeling and characterization of next-generation fixed multiple-antennas and mobile satellite systems, as well as propagation phenomena and fade mitigation techniques. The frequencies of interest range from 100 MHz to 100 GHz (from VHF to W band), whereas the use of optical free-space communications is envisaged.Examining recent research advances in space-time tropospheric propagation fields and optical satellite communication channel models, the book covers land mobile multiple antennas satellite- issues and relative propagation campaigns and stratospheric channel models for various applications and frequencies. It also presents research and well-accepted satellite community results for land mobile satellite and tropospheric attenuation time-series single link and field synthesizers.The book examines aeronautical communications channel characteristics and modeling, relative radio wave propagation campaigns, and stratospheric channel model for various applications and frequencies. Propagation effects on satellite navigation systems and the corresponding models are also covered.

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As an intermediate model between conventional PKC and ID-PKC, CL-PKC can avoid the heavy overhead of certificate management in traditional PKC as well as the key escrow problem in ID-PKC altogether. Since the introduction of CL-PKC, many concrete constructions, security models, and applications have been proposed during the last decade. Differing from the other books on the market, this one provides rigorous treatment of CL-PKC.Definitions, precise assumptions, and rigorous proofs of security are provided in a manner that makes them easy to understand.

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Disposal and Management of Solid Waste: Pathogens and Diseases takes a closer look at pathogens that are found in solid wastes and the diseases that they produce. While comparing the differences between developed and developing countries, this book provides an understanding of the risks and exposure of pathogens in solid wastes, addresses pathogens in soil and plants, and bioaerosols, and helps readers determine how pathogens can be directly or indirectly detrimental to human health. The text places special emphasis on developing countries where environmentally safe systems are relatively rare, and provides extensive details on potential sources of infection and disease. The author discusses the transmission routes of diseases and pathogens from various solid wastes, and presents the proper disposal options and the management of solid waste.This book covers: Global aspects of pathogens and diseases from solid waste Pathogens and diseases in various solid wastes other than hospital wastes Disposal and management of solid wastes in relation to diseases Disposal and Management of Solid Waste: Pathogens and Diseases describes the various pathogens and diseases that can be found in solid waste, and utilizes recent available data to offer insight and suggestions on the management and disposal of solid waste to reduce infection and disease.

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Much has been written about U.S. intelligence operations. However, intelligence, as it is conducted in the U.S. domestic environment, has usually been treated in a fractured and sensationalistic manner. This book dispassionately assesses the U.S. domestically oriented intelligence enterprise by first examining its individual components and then showing how those components, both federal and non-federal, work in conjunction to form an often unacknowledged structure that is more than the sum of its parts. The U.S. Domestic Intelligence Enterprise: History, Development, and Operations takes a unique, in-depth approach that assesses not only the current state of affairs but also the evolution of the domestic intelligence enterprise. To accomplish this, it examines the origins and progress of the major agencies to show why they operate in the way that they do. By providing this perspective, the book promotes an understanding of the factors to consider when developing effective intelligence policy. The book is divided into several thematic sections: The evolution of the domestically oriented intelligence enterprise The collection capabilities of the enterprise The role that domestically-developed intelligence has in the analytical process, which informs decision making The use of intelligence to implement decisions via disruption of threat actors The U.S. Domestic Intelligence Enterprise intends to prompt a rethinking of intelligence within the domestic environment. It takes into account the political realities, the organizational cultures, and the evolving missions that have shaped those agencies responsible for positive and negative intelligence and disruption of threats on American soil. This will hopefully provide a counterweight to future knee-jerk reactions and, instead, inspire a thoughtful approach to the advancement of U.S. strategic interests while protecting the rights of Americans.

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Polysaccharides and related high molecular weight glycans are hugely diverse with wide application in Biotechnology and great opportunities for further exploitation. An Introduction to Polysaccharide Biotechnology – a second edition of the popular original text by Tombs and Harding – introduces students, researchers, clinicians and industrialists to the properties of some of the key materials involved, how these are applied, some of the economic factors concerning their production and how they are characterized for regulatory purposes.

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The book examines crisis management for operations located outside of a corporation’s normal confines, particularly in regions which might be overtly threatening or hostile to multinational corporations and their people and assets overseas. Outlining proper operating procedures, planning, implementation, and drills, it demonstrates how proper planning and effective management systems in place prior to a crisis can mean the difference between life and death. The book helps organizations establish best practices in crisis management to ensure safety and security of personnel, assets, and properties overseas, even in potentially volatile environments.

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Radioactive sources such as nuclear power installations can pose a great threat to both humans and our environment. How do we measure, model and regulate such threats? Environmental Radioactivity and Emergency Preparedness addresses these topical questions and aims to plug the gap in the lack of comprehensive literature in this field. The book explores how to deal with the threats posed by different radiological sources, including those that are lost or hidden, and the issues posed by the use of such sources. It presents measurement methods and approaches to model and quantify the extent of threat, and also presents strategies for emergency preparedness, such as strategies for first-responders and radiological triage in case an accident should happen. Containing the latest recommendations and procedures from bodies such as the IAEA, this book is an essential reference for both students and academicians studying radiation safety, as well as for radiation protection experts in public bodies or in the industry.

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Written in a way that facilitates understanding of complex concepts, laws, and policy, Production, Growth, and the Environment: An Economic Approach explores how economic growth usually makes people better off, but also asks at what environmental cost? These costs are not often realized until after the fact, when their remediation is more expensive, and sometimes not reversible. Very few books on environmental economics model the joint production of desirable and undesirable outcomes in any depth. This book fills that void. It discusses the demographic transition and the escape from the Malthusian trap. It also covers the environmental Kuznets curve hypothesis that examines the relation between polluting outputs and economic welfare. The book integrates environmental valuation methods with the production possibility frontier (PPF) approach. It presents both types of outcomes in a PPF framework that accounts for scarcity and allows the concepts of technical and allocative efficiencies to be introduced and measured. The PPF can then measure technological progress/regress and can be used to measure whether resource use is sustainable over time. It can also be used to determine shadow prices for non-market desirable outputs such as ecological services and non-market undesirable by-products such as SO2, NOx, and CO2 that arise from fossil fuel combustion.The beauty of the PPF framework is that it can be depicted in simple two-dimensional diagrams that make the concepts easy to understand. The author uses this framework to introduce concepts such as technical efficiency, allocative efficiency, technological progress/regress, shadow pricing, externalities, public goods, pollution taxes, and permits. In addition, each chapter has numerous problems and discussion questions that provide examples and practice in using the introduced theories. The book also includes a chapter that shows how the solver routine in Excel can be used to measure technical and allocative efficiency. This gives you the tools to examine all outcomes and therefore make a decision that takes into account the environmental challenges along with any economic benefits.

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Many wetlands around the world act as sinks for pollutants, in particular for trace elements. In comparison to terrestrial environments, wetlands are still far less studied. A collaborative effort among world experts, this book brings the current knowledge concerning trace elements in temporary waterlogged soils and sediments together. It discusses factors controlling the dynamics and release kinetics of trace elements and their underlying biogeochemical processes. It also discusses current technologies for remediating sites contaminated with trace metals, and the role of bioavailability in risk assessment and regulatory decision making. This book is intended for professionals around the world in disciplines related to contaminant bioavailability in aquatic organisms, contaminant fate and transport, remediation technologies, and risk assessment of aquatic and wetland ecosystems.

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Sharpening Your Advanced SAS® Skills presents sophisticated SAS programming techniques, procedures, and tools, such as Proc SQL, hash tables, and SAS Macro programming, for any industry. Drawing on his more than 20 years’ experience of SAS programming in the pharmaceutical industry, the author provides a unique approach that empowers both advanced programmers who need a quick refresher and programmers interested in learning new techniques.The book helps you easily search for key points by summarizing and differentiating the syntax between similar SAS statements and options. Each chapter begins with an overview so you can quickly locate the detailed examples and syntax. The basic syntax, expected data, and descriptions are organized in summary tables to facilitate better memory recall. General rules list common points about similar statements or options. Real-world examples of SAS programs and code statements are line numbered with references, such as SAS papers and websites, for more detailed explanations. The text also includes end-of-chapter questions to reinforce your knowledge of the topics and prepare you for the advanced SAS certification exam. In addition, the author’s website offers mindmaps and process flowcharts that connect concepts and relationships.

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Adding new results that have appeared in the last 15 years, Dictionary of Inequalities, Second Edition provides an easy way for researchers to locate an inequality by name or subject. This edition offers an up-to-date, alphabetical listing of each inequality with a short statement of the result, some comments, references to related inequalities, and sources of information on proofs and other details. The book does not include proofs and uses basic mathematical terminology as much as possible, enabling readers to access a result or inequality effortlessly.New to the Second Edition More than 100 new inequalities, including recently discovered ones Updated inequalities according to the most recent research Inclusion of a name index Updated bibliography that contains URLs for important references The book mainly presents the most common version of the inequality and later gives more general results as extensions or variants. Inequalities that exist at various levels of generality are presented in the simplest form with the other forms as extensions or under a different heading. The author also clarifies any non-standard notations and includes cross-references for transliterations.

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Handbook of Visual Optics offers an authoritative overview of encyclopedic knowledge in the field of physiological optics. It builds from fundamental concepts to the science and technology of instruments and practical procedures of vision correction, integrating expert knowledge from physics, medicine, biology, psychology, and engineering. The chapters comprehensively cover all aspects of modern study and practice, from optical principles and optics of the eye and retina to novel ophthalmic tools for imaging and visual testing, devices and techniques for visual correction, and the relationship between ocular optics and visual perception.

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The concept of the Euclidean simplex is important in the study of n-dimensional Euclidean geometry. This book introduces for the first time the concept of hyperbolic simplex as an important concept in n-dimensional hyperbolic geometry. Following the emergence of his gyroalgebra in 1988, the author crafted gyrolanguage, the algebraic language that sheds natural light on hyperbolic geometry and special relativity. Several authors have successfully employed the author’s gyroalgebra in their exploration for novel results. Françoise Chatelin noted in her book, and elsewhere, that the computation language of Einstein described in this book plays a universal computational role, which extends far beyond the domain of special relativity. This book will encourage researchers to use the author’s novel techniques to formulate their own results. The book provides new mathematical tools, such as hyperbolic simplexes, for the study of hyperbolic geometry in n dimensions. It also presents a new look at Einstein’s special relativity theory.

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Adverse Drug Interactions: A Handbook for Prescribers assists clinicians by providing key information on potential adverse effects that can result from prescribing two or more drugs for simultaneous use. Interactions that are likely to give rise to life-threatening conditions, and which must therefore be completely avoided, are clearly highlighted. Less threatening but nonetheless important interactions necessitating practical measures, such as frequent monitoring and advice to patients, are also discussed.Presented in a user-friendly format, the book is organised by drug class and provides a brief summary of the mechanism underlying a particular interaction, alternative drugs lacking the same reactions that may be considered, and instructions for monitoring patients when adverse effects occur. All interactions listed in the previous edition have been reviewed and updated using the latest information available. The clinical reality of the widespread use of potent medicines, whether allopathic, herbal or traditional, has led to the inclusion of a chapter specifically addressing over-the-counter drugs and remedies. Importantly, the increasing relevance of drug interactions due to genetic polymorphisms of metabolizing enzymes and drug transporters and the associated influence of these in ethnic groups is discussed. Also discussed is the risk of interactions in many vulnerable population groups (e.g. infancy, pregnancy, infections, liver and kidney disease).This quick and easy reference guide brings together the current evidence base with a broad range of practical prescribing experience to produce a source of advice that can be used in the clinic, pharmacy, or at the patient’s bedside.

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Monomial Algebras, Second Edition presents algebraic, combinatorial, and computational methods for studying monomial algebras and their ideals, including Stanley–Reisner rings, monomial subrings, Ehrhart rings, and blowup algebras. It emphasizes square-free monomials and the corresponding graphs, clutters, or hypergraphs. New to the Second Edition Four new chapters that focus on the algebraic properties of blowup algebras in combinatorial optimization problems of clutters and hypergraphs Two new chapters that explore the algebraic and combinatorial properties of the edge ideal of clutters and hypergraphs Full revisions of existing chapters to provide an up-to-date account of the subject Bringing together several areas of pure and applied mathematics, this book shows how monomial algebras are related to polyhedral geometry, combinatorial optimization, and combinatorics of hypergraphs. It directly links the algebraic properties of monomial algebras to combinatorial structures (such as simplicial complexes, posets, digraphs, graphs, and clutters) and linear optimization problems.

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Glutamine: Biochemistry, Physiology, and Clinical Applications describes the different functions of glutamine (Gln) in animals and humans. Gln is both a nutrient and a signaling molecule, and its functions go beyond those of a simple metabolic fuel or protein precursor. This book has gathered together, in an unbiased and critical manner, all the available evidence and research on Gln including pathology (neurological diseases, intestinal diseases, critical illness, and cancer), physiology (successful aging), catabolic states, immunity, and exercise. Special attention is given to the potential benefit of Gln in states of insulin resistance and the role of Gln as a "conditionally essential" amino acid. The contributors are either pioneers or experts in the area of Gln from all around the globe, including Australia, Brazil, Canada, Europe, China, and the United States. This book is a valuable source of information for nutrition scientists, medical doctors, sports scientists, food scientists, dietitians, and anyone interested in nutrition. It is also a valuable resource for students in these fields and will be an important addition to university libraries.

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Evolutionary biology has increasingly relied upon tools developed in molecular biology that allow for the structure and function of macromolecules to be used as data for exploring the patterns and processes of evolutionary change. Integrated Molecular Evolution, Second Edition is a textbook intended to expansively and comprehensive review evolutionary studies now routinely using molecular data. This new edition has been thoroughly updated and expanded, and provides a basic summary of evolutionary biology as well as a review of current phylogenetics and phylogenomics.Reflecting a burgeoning pedagogical landscape, this new edition includes nearly double the number of chapters, including a new section on molecular and bioinformatic methods. Dedicated chapters were added on: Evolution of the genetic code Mendelian genetics and population genetics Natural selection Horizontal gene transfers Animal development and plant development Cancer Extraction of biological molecules Analytical methods Sequencing methods and sequencing analyses Omics Phylogenetics and phylogenetic networks Protein trafficking Human genomics More than 400 illustrations appear in this edition, doubling the number included in the first edition, and over 100 of these diagrams are now in color.The second edition combines and integrates extensive summaries of genetics and evolutionary biology in a manner that is accessible for students at either the graduate or undergraduate level. It also provides both the basic foundations of molecular evolution, such as the structure and function of DNA, RNA and proteins, as well as more advanced chapters reviewing analytical techniques for obtaining sequences, and interpreting and archiving molecular and genomic data.

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Building Wireless Sensor Networks: Theoretical and Practical Perspectives presents the state of the art of wireless sensor networks (WSNs) from fundamental concepts to cutting-edge technologies.Focusing on WSN topics ideal for undergraduate and postgraduate curricula, this book: Provides essential knowledge of the contemporary theory and practice of wireless sensor networking Describes WSN architectures, protocols, and operating systems Details the routing and data aggregation algorithms Addresses WSN security and energy efficiency Includes sample programs for experimentation The book offers overarching coverage of this exciting field, filling a critical gap in the existing literature.

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Is Bigger Always Better? Explore the Behavior of Very Small Devices as Described by Quantum MechanicsSmaller is better when it comes to the semiconductor transistor. Nanoscale Silicon Devices examines the growth of semiconductor device miniaturization and related advances in material, device, circuit, and system design, and highlights the use of device scaling within the semiconductor industry. Device scaling, the practice of continuously scaling down the size of metal-oxide-semiconductor field-effect transistors (MOSFETs), has significantly improved the performance of small computers, mobile phones, and similar devices. The practice has resulted in smaller delay time and higher device density in a chip without an increase in power consumption. This book covers recent advancements and considers the future prospects of nanoscale silicon (Si) devices. It provides an introduction to new concepts (including variability in scaled MOSFETs, thermal effects, spintronics-based nonvolatile computing systems, spin-based qubits, magnetoelectric devices, NEMS devices, tunnel FETs, dopant engineering, and single-electron transfer), new materials (such as high-k dielectrics and germanium), and new device structures in three dimensions. It covers the fundamentals of such devices, describes the physics and modeling of these devices, and advocates further device scaling and minimization of energy consumption in future large-scale integrated circuits (VLSI).Additional coverage includes: Physics of nm scaled devices in terms of quantum mechanics Advanced 3D transistors: tri-gate structure and thermal effects Variability in scaled MOSFET Spintronics on Si platform NEMS devices for switching, memory, and sensor applications The concept of ballistic transport The present status of the transistor variability and more An indispensable resource, Nanoscale Silicon Devices serves device engineers and academic researchers (including graduate students) in the fields of electron devices, solid-state physics, and nanotechnology.

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A Classroom-Tested, Alternative Approach to Teaching Math for Liberal Arts Puzzles, Paradoxes, and Problem Solving: An Introduction to Mathematical Thinking uses puzzles and paradoxes to introduce basic principles of mathematical thought. The text is designed for students in liberal arts mathematics courses. Decision-making situations that progress from recreational problems to important contemporary applications develop the critical-thinking skills of non-science and non-technical majors. The logical underpinnings of this textbook were developed and refined throughout many years of classroom feedback and in response to commentary from presentations at national conferences. The text’s five units focus on graphs, logic, probability, voting, and cryptography. The authors also cover related areas, such as operations research, game theory, number theory, combinatorics, statistics, and circuit design. The text uses a core set of common representations, strategies, and algorithms to analyze diverse games, puzzles, and applications. This unified treatment logically connects the topics with a recurring set of solution approaches. Requiring no mathematical prerequisites, this book helps students explore creative mathematical thinking and enhance their own critical-thinking skills. Students will acquire quantitative literacy and appreciation of mathematics through the text’s unified approach and wide range of interesting applications.

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How-To Guide Written By Practicing ProfessionalsPhysical Security and Safety: A Field Guide for the Practitioner introduces the basic principles of safety in the workplace, and effectively addresses the needs of the responsible security practitioner. This book provides essential knowledge on the procedures and processes needed for loss reduction, protection of organizational assets, and security and safety management. Presents Vital Information on Recognizing and Understanding Security NeedsThe book is divided into two parts. The first half of the text, Security and Safety Planning, explores the theory and concepts of security and covers: threat decomposition, identifying security threats and vulnerabilities, protection, and risk assessment. The second half, Infrastructure Protection, examines the overall physical protection program and covers: access and perimeter control, alarm systems, response force models, and practical considerations for protecting information technology (IT). Addresses general safety concerns and specific issues covered by Occupational Safety and Health Administration (OSHA) and fire protection regulations Discusses security policies and procedures required for implementing a system and developing an attitude of effective physical security Acts as a handbook for security applications and as a reference of security considerations Physical Security and Safety: A Field Guide for the Practitioner offers relevant discourse on physical security in the workplace, and provides a guide for security, risk management, and safety professionals.

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Actuarial Models: The Mathematics of Insurance, Second Edition thoroughly covers the basic models of insurance processes. It also presents the mathematical frameworks and methods used in actuarial modeling. This second edition provides an even smoother, more robust account of the main ideas and models, preparing students to take exams of the Society of Actuaries (SOA) and the Casualty Actuarial Society (CAS).New to the Second Edition Revises all chapters, especially material on the surplus process Takes into account new results and current trends in teaching actuarial modeling Presents a new chapter on pension models Includes new problems from the 2011-2013 CAS examinations Like its best-selling, widely adopted predecessor, this edition is designed for students, actuaries, mathematicians, and researchers interested in insurance processes and economic and social models. The author offers three clearly marked options for using the text. The first option includes the basic material for a one-semester undergraduate course, the second provides a more complete treatment ideal for a two-semester course or self-study, and the third covers more challenging topics suitable for graduate-level readers.

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Dermatoscopy has been heavily promoted to dermatologists as the front line in detecting skin cancer early and easily. However, this technology also has other uses in everyday dermatologic practice.Dermatoscopy in Clinical Practice shows those already using the equipment how they can extend its use beyond pigmented lesions and exploit its full potential. Dermatoscopy and videodermatoscopy can be used for differential diagnosis, prognostic evaluation, and monitoring response to treatment of various disorders including inflammatory diseases, parasitoses, viral and fungal infections, nonpigmented skin lesions, hair abnormalities, and a large variety of other dermatologic conditions as well as cosmetology. The book focuses on those conditions in which the techniques are most useful, describing the clinical and histopathological correlations associated with the procedure. The book includes color clinical images throughout, making it a handy guide for the dermatologist’s daily practice.

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