Search results for ""pan stanford publishing pte ltd""

In recent decades, metrology—an accurate and precise technology of high quality for automotive engines—has garnered a great deal of scientific interest due to its unique advanced soft engineering techniques in design and diagnostics. Used in a variety of scientific applications, these techniques are now widely regarded as safer, more efficient, and more effective than traditional ones. This book compiles and details the cutting-edge research in science and engineering from the Egyptian Metrology Institute (National Institute for Standards) that is revolutionizing advanced dimensional techniques through the development of coordinate and surface metrology.

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Nanotechnology has attracted billions of dollars in venture capital from research institutes, governments, and industries in recent years. Traditional nanofabrication techniques such as CVD, sol–gel, and self-assembly have been intensively studied. However, the electrochemical nanofabrication technique, which offers huge benefits for manufacturing nanomaterials as well as broad applications in industries, has not been given much attention compared with the traditional nanofabrication methods. This book fits the niche of such technology because it summarizes various electrochemical nanofabrication methods and shows their various essential applications in areas such as batteries, sensors, and many future technologies. With the development of nanotechnology and nanomaterials, the arena of electrochemical nanofabrication has expanded significantly. The first edition of this book was drafted in 2009. In 2010, the Nobel Prize in Physics was awarded to Prof. Konstantin Novoselov and Prof. Andre Geim from the University of Manchester for their groundbreaking experiments on the two-dimensional material graphene. Three years later, the European Commission launched the European Union’s biggest ever research initiative, the Graphene Flagship, with a budget of 1 billion euros. In light of these developments, this new edition of the book is enriched with the synthesis of graphene-based materials through electrochemical methods, the applications of graphene in lithium-ion and sodium-ion batteries, and the use of graphene composites in various sensing platforms. It will be of immense interest to a broad audience in nanotechnology and electrochemistry.

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Hydrogels are an emerging area of interest in medicine as well as pharmaceutics, and their physico-chemical characterization is fundamental to their practical applications. Compared with synthetic polymers, polysaccharides that are widely present in living organisms and come from renewable sources are extremely advantageous for hydrogel formation. Furthermore, polysaccharides are usually non-toxic and biocompatible and show a number of peculiar physico-chemical properties that make them suitable for a wide variety of biomedical applications. This book bridges the gap between the preparation of hydrogels and their characterization techniques. It aims to offer a valid support that can help the readers find appropriate keys to open the doors to the complex world of polysaccharide hydrogels.

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Metal-organic frameworks (MOFs) have emerged as a new family of nanoporous materials. With an enormous choice of inorganic/organic building blocks, MOFs possess a wide range of surface area, pore size, and functionality and, thus, have been considered versatile materials for many potential applications. This book presents a broad collection of recent modeling studies in the field of MOFs toward potential engineering applications, such as gas storage/separation, carbon capture, catalysis, water purification, and drug delivery.

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Interferometric observations need snapshots of very high time resolution of the order of (i) frame integration of about 100 Hz or (ii) photon-recording rates of several megahertz (MHz). Detectors play a key role in astronomical observations, and since the explanation of the photoelectric effect by Albert Einstein, the technology has evolved rather fast. The present-day technology has made it possible to develop large-format complementary metal oxide–semiconductor (CMOS) and charge-coupled device (CCD) array mosaics, orthogonal transfer CCDs, electron-multiplication CCDs, electron-avalanche photodiode arrays, and quantum-well infrared (IR) photon detectors. The requirements to develop artifact-free photon shot noise-limited images are higher sensitivity and quantum efficiency, reduced noise that includes dark current, read-out and amplifier noise, smaller point-spread functions, and higher spectral bandwidth. This book aims to address such systems, technologies and design, evaluation and calibration, control electronics, scientific applications, and results.One of the fastest growing applications is signal sensing, especially wavefront sensing for adaptive optics and fringe tracking for interferometry, which is important for long-baseline optical interferometry. The coherence time of the atmosphere is a highly variable parameter. Depending upon the high velocity wind, it varies from <1 ms to 0.1 s. The exposure times are to be selected accordingly, to maximize the signal-to-noise ratio, as well as to freeze the fringe pattern. A large-format photon-counting system, which is an essential tool in the application of optical interferometric imaging, allows accurate photon centroiding and provides the dynamic range needed for measurements of source characteristics. The advent of high-quantum efficiency photon-counting systems vastly increases the sensitivity of high-resolution imaging techniques. Such systems raise the hope of making diffraction-limited images of objects as faint as ~15–16 m_v (visual magnitude).This book deals with the fundamentals of the important aspects of high-resolution imaging, such as electromagnetic radiations, particularly, optical wavelengths and their distortions due to optical elements and Earth’s atmosphere while passing through a detector; semiconductor physics; lasers; fiber optics; photon-detection process; photodetectors; charge-transfer devices; photon-counting devices in visible wavelength; radiation detectors in infrared wavelengths; and detecting systems for high energies.

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While the sustainability of our world is being endangered or destroyed by the misguided activities of artificial human entities, real people have begun to expand their moral sympathies sufficiently to prioritize protecting our world’s interests. They have developed a new technology—nanotechnology—that has the potential to advance human society toward a period of long-term sustainability, termed "the Sustainocene." This book comprises chapters by experts in various fields of nanotechnology and in related areas of governance under the theme of how nanotechnology can assist in the creation of the Sustainocene. The book will appeal to anyone involved in nanotechnology, macromolecular science, public policy related to sustainability, renewable energy, and climate change.

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This book explores why cobalt oxides have drawn interest as functional materials due to their peculiar physical properties partially originating from a rich variety of the valence and spin state of cobalt ions. The book starts with the basics of condensed matter physics and advances toward the strong electron correlation system stage. It also provides up-to-date information on topics, such as thermoelectric power, superconductivity, solid oxide fuel cells, and nanostructure effect.

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Energy transport and conversion in nanoscale structures is a rapidly expanding area of science. It looks set to make a significant impact on human life and, with numerous commercial developments emerging, will become a major academic topic over the coming years. Owing to the difficulty in experimental measurement, computational simulation has become a powerful tool in the study of nanoscale energy transport and harvesting.This book provides an introduction to the current computational technology and discusses the applications of nanostructures in renewable energy and the associated research topics. It will be useful for theorists, experimentalists, and graduate-level students who want to explore this new field of research. The book addresses the currently used computational technologies and their applications in study of nanoscale energy transport and conversion. With content relevant to both academic and commercial viewpoints, it will interest researchers and postgraduates as well as consultants in the renewable energy industry.

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The book describes the industrial revolution associated with the implementation of electric power generation by photovoltaics (PV). The book’s editor and contributing authors are among the leading pioneers in PV from its industrial birth in 1954 all the way up to the stormy developments during the first decade of the new century. The book describes the dramatic events in industry between 2009 and 2013 and puts all this into perspective. It concludes that solar power is yet to strengthen its role in technology and in mainstream of the world’s economy.

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This book covers electronic and structural properties of light-induced defects, light-induced defect creation processes, and related phenomena in crystalline, amorphous, and microcrystalline semiconductors. It provides a theoretical treatment of recombination-enhanced defect reaction in crystalline semiconductors, particularly GaAs and related materials. It also discusses experimental evidence for this phenomenon. Light-induced defect creation in hydrogenated amorphous silicon (a-Si:H) is described in more detail, including its mechanism and experimental results. The subjects treated by the book are important issues from the viewpoints of physics and applications.

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A comprehensive overview, this book focuses on two directions of study: discovery of new effects that take place in magnetic wires and optimization of the magnetic, electrical, and mechanical properties of the wires, taking into account the technological application. The book presents the idea of moving to nanoscale, maintaining the achieved optimal parameters of microwires. While the focus remains on glass-covered wires of micrometer scale, it covers the first steps of the movement to "nano" range as an example of the versatility of the basic effects initially discovered for microscale.

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Nanocomposite materials as a special class of nanostructured materials have recently attracted great interest due to their extraordinary mechanical properties as well as thermal stability and oxidation resistance. The unique structure and exceptional properties make nanocomposite materials a possible alternative to traditional polycrystalline materials, which have met their limits in many recent engineering applications. In particular, nanocomposite coatings synthesized by plasma-assisted deposition processes under highly non-equilibrium conditions provide a high potential for new applications as protective and functional coatings in automotive, aerospace, tooling, electronic, or manufacturing industry.This book provides a comprehensive overview of the synthesis of Si-containing hard nanocomposite coatings based on transition metal nitrides by plasma-based thin film processing. It demonstrates the full versatility of these nanocomposites for low Si-containing coatings tailored with superior mechanical properties and novel high Si-containing nanocomposite coatings with extraordinary thermal stability and resistance against oxidation optimized for high-temperature applications. It pays special attention to understanding growth mechanisms of these structures under specific deposition conditions, structure–property relations, and stability of individual constituents to enhance their functionality for various applications.

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Nanotechnology brings new possibilities for the development of sensors, biosensors, and novel electrochemical bioassays. Nanoscale materials have been extensively used in a wide variety of configurations — as electrode surfaces to promote electrochemical reaction, as "wires" to enzymes connecting their redox centers to electrode surface, as nanobarcodes for biomolecules, or as tags to amplify the signal of a biorecognition event.Nanomaterial-based electrochemical sensors have been used in many areas, including cancer diagnostics and the detection of infectious organisms. This book reviews important achievements in the field of nanomaterial-based electrochemical sensors and biosensors.

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This book illustrates a variety of challenges that bug hunters try to solve. It is an outstanding collection of the insights and expertise of an interdisciplinary group of researchers from all walks of life: virologists, physicians, immunologists, electrochemists, physicists, computer scientists, biotechnologists, epidemiologists, and molecular biologists, all working at the forefront of diagnostics in fields that cross scientific boundaries. Notwithstanding a dire moment as that of the recent Ebola outbreak in West Africa that saddens us all, we must more than ever peregrinate across oceans, and take the fight to them, as these invisible and exotic but deadly enemies know no barriers and constantly invade our lives. The coming epidemics and killer pandemics require us to continuously innovate in areas of prevention, detection, and therapy. The present volume focuses on creating virus alerts or hand-held detectors to bring to the field during an epidemic, when possible, or tools for the healthcare worker to rapidly diagnose the patient’s ailment. The authors describe the conventional cell cultures and molecular biology methodologies, while introducing state-of-the-art multidisciplinary biosensors. This book is not a manual, set of protocols, or a textbook; it is a glimpse into the advances of virus diagnostic research. Included are a variety of topics that encompass world health issues, local folklore such as associating outbreaks with witchcraft, problems in getting healthcare workers to the outbreak areas, and insights in viral diagnostic pitfalls.

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The design and synthesis of molecularly or supramolecularly defined interfacial architectures have seen in recent years a remarkable growth of interest and scientific research activities for various reasons. On the one hand, it is generally believed that the construction of an interactive interface between the living world of cells, tissue, or whole organisms and the (inorganic or organic) materials world of technical devices such as implants or medical parts requires proper construction and structural (and functional) control of this organism–machine interface. It is still the very beginning of generating a better understanding of what is needed to make an organism tolerate implants, to guarantee bidirectional communication between microelectronic devices and living tissue, or to simply construct interactive biocompatibility of surfaces in general.This exhaustive book lucidly describes the design, synthesis, assembly and characterization, and bio-(medical) applications of interfacial layers on solid substrates with molecularly or supramolecularly controlled architectures. Experts in the field share their contributions that have been developed in recent years.

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Nanoscale materials are showing great promise in various electronic, optoelectronic, and energy applications. Silicon (Si) has especially captured great attention as the leading material for microelectronic and nanoscale device applications. Recently, various silicides have garnered special attention for their pivotal role in Si device engineering and for the vast potential they possess in fields such as thermoelectricity and magnetism. The fundamental understanding of Si and silicide material processes at nanoscale plays a key role in achieving device structures and performance that meet real-world requirements and, therefore, demands investigation and exploration of nanoscale device applications. This book comprises the theoretical and experimental analysis of various properties of silicon nanocrystals, research methods and techniques to prepare them, and some of their promising applications.

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The book places nanotechnology’s emergence within a broad historical and contemporary global context while developing and testing an interpretive framework through which to assess nanotechnology’s claims. It clarifies the nature of global engagement with nanotechnology research and development, revealing surprising scenarios, unacknowledged by most mainstream commentators. The book concludes by exploring a range of perspectives from Thailand and Australia about nanotechnology’s foreseen implications for global inequity.

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Superconductors (SCs) are attractive materials in all respects for any community. They provide a deep insight into the physical properties of the condensed matters and also have useful applications as ultra-low-power-dissipation systems that can help resolve the present energy problems. In particular, the recent advancement of carbon-based new superconductors (CNSCs) is significant. Before 2004, the superconducting transition temperature (Tc) of carbon-based SCs was below 1 K, except in fullerene clusters. However, in 2004, a Russian group discovered that diamond highly doped with boron could be an SC at Tc = 4 K. The following year, a group from Cambridge found that calcium-intercalated graphite could be an SC with Tc = 11.5 K. In 2006 and 2008, the editor’s group from Japan also discovered that carbon nanotubes could be SCs at Tc = 12 K. Since then, research on CNSCs has increased notably.A small mass of carbon can produce high phonon frequency and high Debye temperature. Combining these with other specified properties of CNSCs (such as one-dimensional electronic states) is highly expected to open doors to high-Tc superconductivity like those of CuO2- and Fe-based SCs, which were the only SCs to show Tc > 40 K in the past. CNSCs, such as diamond, graphite, carbon nanotubes, fullerenes, and others, are a very attractive field of research, and this book is the first to describe their basic physics and the recent advances toward high Tc in this field.

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This is the first text to be written on the topic of Self-Field Theory (SFT), a new mathematical description of physics distinct from quantum field theory, the physical theory of choice by physicists at the present time. SFT is a recent development that has evolved from the classical electromagnetics of the electron’s self-fields that were studied by Abraham and Lorentz in 1903-04. Due to its bi-spinorial motions for particles and fields that obviate uncertainty, SFT is capable of obtaining closed-form solution for all atomic structures rather than the probabilistic solutions of QFT.

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The fast developing field of nanomedicine uses a broad variety of materials to serve as delivery systems for drugs, genes, and diagnostic agents. This book is the first attempt to put under one cover all major available information about these materials, both still on experimental levels and already applied in patients.

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The challenge of providing adequate power on an indefinite basis without causing long-term damage to the environment requires a versatile means of energy conversion and storage. As such, electrical energy storage is becoming more vital today than at any time in human history. Electrochemical systems, such as batteries, supercapacitors, fuel cells, and photoelectrochemical cells, can help meet this objective. Future generations of rechargeable lithium batteries will be required to power portable electronic devices, store electricity from renewable sources, and serve as a vital component to pursuing electric mobility in the future to reduce fossil fuel demand and mitigate environmental issues. In this context, engineering of new materials, especially at the nanoscale, has become imperative to achieve enhanced energy and power density to meet the future challenges of energy storage. This book outlines the state of the art of nanoscale aspects of advanced energy storage devices, such as lithium-ion batteries, including microbatteries and electrochemical supercapacitors. It focuses on various fundamental issues related to device performance of various positive and negative electrode materials, with special reference to their nanoscale advantages. It also includes fundamentals and processing techniques with regard to synthesis, characterization, physical, and electrochemical properties, and applications of nanoscale materials pertaining to advanced electrochemical power sources. A variety of advanced nanomaterials, such as transition metal oxides, phosphates, silicates, and conversion electrodes, together with some special nanomaterials such as carbon nanotubes, nanorods, and mesoporous carbons are discussed by many notable authorities in the field.

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This volume introduces, in a coherent and comprehensive fashion, the Pan Stanford Series on Nanobiotechnology by defining and reviewing the major sectors of nanobiotechnology and nanobiosciences with respect to the most recent developments. It covers the basic principles and main applications of nanobiotechnology as an emerging field at the frontiers of biotechnology and nanotechnology, with contributions from leading scientists active in their respective specialties.

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In this book, internationally recognized researchers give a state-of-the-art overview of the electronic device architectures required for the nano-CMOS era and beyond. The book covers the fundamental limits of core CMOS, improving scaling by the introduction of new materials or processes, multigates and multichannels, and quantum computing.

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This timely book provides an overview of possible therapeutic applications. The first part of the book highlights general properties of and phenomena observed with nanoparticles, and the subsequent consequences for applications in drug delivery. The second part focuses on the therapeutic approaches that are possible through the use of nanoparticles, with each chapter discussing a specific disease (e.g., diabetes, cancer, inflammation) and the relevant therapeutic approaches based on the design of nanoparticulate drug delivery systems. From this concise book, readers will gain an insight into the basics of nanoparticle preparation and find a more detailed account of what is therapeutically feasible by using nanoparticle approaches.

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This book highlights state-of-the-art qubit implementations in semiconductors and provides an extensive overview of this newly emerging field. Semiconductor nanostructures have huge potential as future quantum information devices as they provide various ways of qubit implementation (electron spin, electronic excitation) as well as a way to transfer quantum information from stationary qubits to flying qubits (photons). Therefore, this book unites contributions from leading experts in the field, reporting cutting-edge results on spin qubit preparation, read-out and transfer. The latest theoretical as well as experimental studies of decoherence in these quantum information systems are also provided. Novel demonstrations of complex flying qubit states and first applications of semiconductor-based quantum information devices are given, too.

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This book presents the material necessary for understanding the physics, operation, design, and performance of modern MOSFETs with nanometer dimensions. It offers a brief introduction to the field and a thorough overview of MOSFET physics, detailing the relevant basics. The authors apply presented models to calculate and demonstrate transistor characteristics, and they include required input data (e.g., dimensions, doping) enabling readers to repeat the calculations and compare their results. The book introduces conventional and novel advanced MOSFET concepts, such as multiple-gate structures or alternative channel materials. Other topics covered include high-k dielectrics and mobility enhancement techniques, MOSFETs for RF (radio frequency) applications, MOSFET fabrication technology.

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What has gone wrong in Japan that has led to innovation crisis? Prof. Eiichi Yamaguchi has been committed to answer this question, and his quest has spanned several years and academic disciplines. Initially it appeared as if it had no context, but when he put the pieces together, he realized that it was actually one story. This book is a summary of his research over the last 20 years, especially after he moved out of the field of physics, to which he had devoted 21 years. He felt that it was essential for him to do his bit to save this sinking ship, or it would be disrespectful to the future generation.The book integrates his research on innovation policy, innovation theory, and trans-science. It begins with a detailed story of the innovation of blue LEDs, for which three Japanese scientists received the Nobel Prize in Physics in 2014. It describes the current innovation and science crises in Japan and presents evidence that the strong international competitiveness of science-based industries in the United States is a result of the invention of the Small Business Innovation Research (SBIR) system. It discusses a new theory of innovation structures, showing the error in Clayton M. Christensen’s argument of “disruptive innovation.” It also proposes a new concept for “paradigm disruptive innovation,” emphasizing that abduction and transilience are essential factors for accomplishing it and that their decline has led to the innovation crisis in Japan. Finally, it analyzes the future vision of the innovation ecosystem, which promotes abduction and transilience, for scientists to develop new science-based industries.

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Nanomaterials have the potential to shift the paradigm for the diagnosis and treatment of many diseases, especially neoplasms, because of the intriguing behaviors associated with their unique size-/shape-influenced chemical, physical, and physiological features. Currently, there is a huge imbalance between the several nanoplatforms reported in the literature and the few ones approved for clinical applications. This disequilibrium affects, in particular, plasmonic nanomaterials, which present no approved platforms and few candidates in clinical trials. This trend can be reversed by promoting collaborations among scientists from different fields as well as by improving the multidisciplinary background of researchers interested in this area. This book is a collection of must-read peer-reviewed papers focusing on (i) the main behaviors of nanomaterials for nanomedicine, (ii) key features nanomaterials need for successful translation to the clinical setting, and (iii) market analysis of nanomaterials at the bedside or on the way. The main aim of this book is to offer a comprehensive point of view to students and researchers in order to promote the translation of new technologies to patients. It is a unique reference for advanced undergraduate- and graduate-level students of nanotechnology and researchers in materials science, nanotechnology, chemistry, biology, and medicine, especially those with an interest in cancer theranostics.

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Since its invention, the integrated circuit has necessitated new process modules and numerous architectural changes to improve application performances, power consumption, and cost reduction. Silicon CMOS is now well established to offer the integration of several tens of billions of devices on a chip or in a system. At present, there are important challenges in the introduction of heterogeneous co-integration of materials and devices with the silicon CMOS 2D- and 3D-based platforms. New fabrication techniques allowing strong energy and variability efficiency come in as possible players to improve the various figures of merit of fabrication technology. Integrated Nanodevice and Nanosystem Fabrication: Breakthroughs and Alternatives is the second volume in the Pan Stanford Series on Intelligent Nanosystems. The book contains 8 chapters and is divided into two parts, the first of which reports breakthrough materials and techniques such as single ion implantation in silicon and diamond, graphene and 2D materials, nanofabrication using scanning probe microscopes, while the second tackles the scaling and architectural aspects of silicon devices through HiK scaling for nanoCMOS, nanoscale epitaxial growth of group IV semiconductors, design for variability co-optimization in SOI FinFETs, and nanowires for CMOS and diversifications.

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The manipulation of light at the nanometer scale is highly pursued for both fundamental sciences and wide applications. The diffraction limit of light sets the limit for the smallest size of photonic devices to the scale of light wavelength. Fortunately, the peculiar properties of surface plasmons in metal nanostructures make it possible to squeeze light into nanoscale volumes and enable the manipulation of light and light–matter interactions beyond the diffraction limit. Studies on surface plasmons have led to the creation of a booming research field called plasmonics. Because of its various scientific and practical applications, plasmonics attracts researchers from different fields, making it a truly interdisciplinary subject.Nanophotonics: Manipulating Light with Plasmons starts with the general physics of surface plasmons and a brief introduction to the most prominent research topics, followed by a discussion of computational techniques for light scattering by small particles. Then, a few special topics are highlighted, including surfaceenhanced Raman scattering, optical nanoantennas, optical forces, plasmonic waveguides and circuits, and gain-assisted plasmon resonances and propagation. The book discusses the fundamental and representative properties of both localized surface plasmons and propagating surface plasmons. It explains various phenomena and mechanisms using elegant model systems with well-defined structures, is illustrated throughout with excellent figures, and contains an extensive list of references at the end of each chapter. It will help graduate-level students and researchers in nanophotonics, physics, chemistry, materials science, nanoscience and nanotechnology, and electrical and electronic engineering get a quick introduction to this field.

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This book deals with the difference electron nanoscope (DEN), whose principles have been invented and realised by the book author. The DEN is based on a smart combination of diffractometric and spectroscopic data and uses a visualisation of three-dimensional difference electron densities (in our case stemming from 3d orbitals) in order to obtain the key quantity involved, the electric field gradient (efg). However, the DEN is no machine, as the title of the book might infer. It is a computer program running on a fast computer system displaying 3D difference electron hyperareas floating in space and the relevant efg as a wire frame model within the unit cell of the sample involved. In this sense, it acts on a sub-nanometer scale (hence the term "nanoscope") and generates images of uncompared symmetrical and physical evidence—and beauty.For the first time, diffractometry and spectroscopy have been integrated for the common synergetic effects that may contribute to a better understanding of electric and magnetic interactions in a crystal. The experimental derivation of the common quantity, the efg, is not confined to iron-containing samples, as the use of Mössbauer spectroscopy might infer, but can also be determined by nuclear quadrupole resonance that is not confined to special nuclides. Hence, the DEN can be applied to a huge multitude of scientifically interesting specimens since the main method involved, diffractometry in a wide sense, has no general limitations at all. So it is a rather universal method, and the monograph might contribute to a wide distribution of the method in the scientific world. Has anyone seen a real orbital before: a real orbital distribution in a crystal unit cell together with its efg tensor ellipsoid? In this book, one can see it.

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The use of light for probing and imaging biomedical media is promising for the development of safe, noninvasive, and inexpensive clinical imaging modalities with diagnostic ability. The advent of ultrafast lasers has enabled applications of nonlinear optical processes, which allow deeper imaging in biological tissues with higher spatial resolution. This book provides an overview of emerging novel optical imaging techniques, Gaussian beam optics, light scattering, nonlinear optics, and nonlinear optical tomography of tissues and cells. It consists of pioneering works that employ different linear and nonlinear optical imaging techniques for deep tissue imaging, including the new applications of single- and multiphoton excitation fluorescence, Raman scattering, resonance Raman spectroscopy, second harmonic generation, stimulated Raman scattering gain and loss, coherent anti-Stokes Raman spectroscopy, and near-infrared and mid-infrared supercontinuum spectroscopy. The book is a comprehensive reference of emerging deep tissue imaging techniques for researchers and students working in various disciplines.

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This book describes at the introductory level how modern technology has made the scenario of the classic science-fiction movie Fantastic Voyage a reality. The movie is about a submarine and its crew members being shrunk to microscopic size and ventured into the body. Exactly 50 years following the release of the film, such reality takes the form of a medical interventional room capable of mimicking this scenario. Based on 15 years of intensive research and development by the world-leading team in this specific field, the book goes through the scenes of the movie while explaining how it is implemented in this first-of-a-kind interventional facility.This is the first book that explains the fundamentals of navigation of therapeutic agents in the vascular network. The scope of the book is twofold: (1) to initiate readers into various technologies, including, but not limited to, nanotechnology, robotics, and biochemistry (more importantly, it shows how critical the integration of all these disciplines is to solving problems that indeed require a multidisciplinary environment); (2) to inspire the younger generation by showing that science and technology can bring one everywhere with the power to transform fiction to reality that can help humankind.

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Today, the concepts of single-electron tunneling (SET) are used to understand and model single-atom and single-molecule nanoelectronics. The characteristics of nanoelectronic devices, especially SET transistors, can be understood on the basis of the physics of nanoelectronic devices and circuit models. A circuit theory approach is necessary for considering possible integration with current microelectronic circuitry. To explain the properties and possibilities of SET devices, this book follows an approach to modeling these devices using electronic circuit theory. All models and equivalent circuits are derived from the first principles of circuit theory. Based on energy conservation, the circuit model of SET is an impulsive current source, and modeling distinguishes between bounded and unbounded currents. The Coulomb blockade is explained as a property of a single junction. In addition, this edition differs from the previous one by elaborating on the section on spice simulations and providing a spice simulation on the SET electron box circuit, including the spice netlist. Also, a complete, new proof of the two-capacitor problem in circuit theory is presented; the importance of this proof in understanding energy conservation in SET circuits cannot be underestimated. This book will be very useful for advanced undergraduate- and graduate-level students of electrical engineering and nanoelectronics and researchers in nanotechnology, nanoelectronic device physics, and computer science.Only book modeling both single-electron tunneling and many electron tunneling from the points of view of electronics; starting from experiments, via a physics description, working towards a circuit description; and based on energy conservation, in electrical circuits, developing the impulse circuit model for single-electron tunneling.

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This book deals with evolving intelligence systems and their use in immune algorithm (IM), particle swarm optimization (PSO), bacterial foraging (BF), and hybrid intelligent system to improve plants, robots, etc. It discusses the motivation behind research on and background of evolving intelligence systems and illustrates IM-based approach for parameter estimation required for designing an intelligent system. It approaches optimal intelligent tuning using a hybrid genetic algorithm–particle swarm optimization (GA-PSO) and illustrates hybrid GA-PSO for intelligent tuning of vector system.

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Over the past few decades, carbon nanomaterials, most commonly fullerenes, carbon nanotubes, and graphene, have gained increasing interest in both science and industry, due to their advantageous properties that make them attractive for many applications in nanotechnology. Another class of the carbon nanomaterials family that has slowly been gaining (re)newed interest is diamond molecules, also called diamondoids, which consist of polycyclic carbon cages that can be superimposed on a cubic diamond lattice. Derivatives of diamondoids are used in pharmaceutics, but due to their promising properties—well-defined structures, high thermal and chemical stability, negative electron affinity, and the possibility to tune their bandgap—diamondoids could also serve as molecular building blocks in future nanodevices. This book is the first of its kind to give an exhaustive overview of the structures, properties, and current and possible future applications of diamondoids. It contains a brief historical account of diamondoids, from the discovery of the first diamondoid member, adamantane, to the isolation of higher diamondoids about a decade ago. It summarizes the different approaches to synthesizing diamondoids. In particular, current research on the conventional organic synthesis and new approaches based on microplasmas generated in high-pressure and supercritical fluids are reviewed and the advantages and disadvantages of the different methods discussed. The book will serve as a reference for advanced undergraduate- and graduate-level students in chemistry, physics, materials science, and nanotechnology and researchers in macromolecular science, nanotechnology, chemistry, biology, and medicine, especially those with an interest in nanoparticles.

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Millions of patients suffer from end-stage organ failure or tissue loss annually, and the only solution might be organ and/or tissue transplantation. To avoid poor biocompatibility–related problems and donor organ shortage, however, around 20 years ago a new, hybridized method combining cells and biomaterials was introduced as an alternative to whole-organ and tissue transplantation for diseased, failing, or malfunctioning organs—regenerative medicine and tissue engineering. This handbook focuses on all aspects of intelligent scaffolds, from basic science to industry to clinical applications. Its 10 parts, illustrated throughout with excellent figures, cover stem cell engineering research, drug delivery systems, nanomaterials and nanodevices, and novel and natural biomaterials. The book can be used by advanced undergraduate- and graduate-level students of stem cell and tissue engineering and researchers in macromolecular science, ceramics, metals for biomaterials, nanotechnology, chemistry, biology, and medicine, especially those interested in tissue engineering, stem cell engineering, and regenerative medicine.

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Plasmonics is an emerging field mainly developed within the past two decades. Due to its unique capabilities to manipulate light at deep subwavelength scales, plasmonics has been commonly treated as the most important part of nanophotonics. Plasmonic-assisted optical microscopy techniques, especially super-resolution microscopy, have shown tremendous potential and attracted much attention. This book aims to collect cutting-edge studies in various optical imaging technologies with advanced performances that are enabled or enhanced by plasmonics. The basic working principles, development details, and potential future direction and perspectives are discussed. Edited by Zhaowei Liu, a prominent researcher in the field of super-resolution microscopy, this book will be an excellent reference for anyone in the field of nanophotonics, plasmonics, and optical microscopy.

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This book covers almost all fields of cancer genetics and genomics for personalized medicine. Targeted therapy, or precision medicine, or personalized medicine is becoming a standard treatment for many diseases, including cancer. However, how much do we know about the personalized medicine approach? This lucid book helps undergraduate and graduate students, professional researchers, and clinicians to better understand the key concept of personalized medicine.The most up-to-date topics on personalized medicine in this book cover the recent trends in and updates on lung, gastric, liver, breast, and other types of cancers. Circulating tumor cell, cell-free circulating DNA, and microRNAs are discussed as new diagnostic and prognostic markers for cancer. The avatar mouse model is also discussed for maximizing treatment efficacy and prognosis prediction, and so is microenvironment as a drug resistance mechanism. With classical and new pathological approaches, the book provides a systemic overview of personalized immunotherapies and hyperthermic intraperitoneal chemotherapy, followed by new emerging fields of hereditary cancer, thereby equipping readers to eventually contribute in developing more advanced tools and therapies for curing cancer.

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Despite substantial evidence showing the feasibility of Atomic Force Microscopy (AFM) to identify cells with altered elastic and adhesive properties, the use of this technique as a complementary diagnostic method remains controversial. This book is designed to be a practical textbook that teaches how to assess the mechanical characteristics of living, individual cells by AFM. Following a step-by-step approach, it introduces the methodology of measurements in the case of both determination of elastic properties and quantification of adhesive properties.

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This book contains fascinating vignettes depicting future societies and the implications which increasing technological change has on society and the environment. The topics discussed include nanotechnology, medicine, computational science, biotechnology, synthetic biology, and cognitive technology, among others in science. In addition, social norms, attitudes, and policy are also featured. The upshot of this combination is an entertaining, educational, and thought-provoking volume.The glimpses into future societies subsequent to the introduction and incorporation of various emerging technologies depict scenarios of how we view ourselves, how we view others, how we are viewed by others, how our surroundings are viewed, how our leaders and political structures are viewed, what our social and behavioral norms are, what our temperament/mood is, and so forth. The introduction features a focused discourse on current trends of the impacts of emerging technologies and the conclusion highlights where society should go from here.

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Transport of pharmaceutical agents in the body is paramount to therapeutic efficacy. Advances in the past decades have rendered a remarkable improvement of drug delivery strategies, which has helped to increase the bioavailability of therapeutic agents by protecting them from degradation, targeting them to diseased sites, and controlling their circulation time and release rate. Additionally, for most therapeutics, reaching the targets of action require penetration across tissues and/or entry within cells. The design of strategies to control the transport of therapeutic compounds through these physiological barriers has become an imperative and a challenging need in the quest for better therapeutics. This book provides an overview of the current advances in this field, including considerations on the biological regulation and natural mechanisms overcoming these barriers, as well as drug delivery strategies facilitating the transport of drugs and their carriers at the tissue, cell, and subcellular levels.

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This book presents state-of-the-art contributions related to advanced structural characterization techniques in the field of clean energy materials with particular emphasis on solid oxide fuel cells and hydrogen storage materials. It describes several diffraction and spectroscopic techniques for the investigation of both average and local structures with several examples of the most recent materials for clean energy applications. It is the first authoritative collection of contributions on the importance of the application of the most advanced structural techniques to shed light on the properties and mechanisms of materials currently investigated for the use in alternative energy devices. The book provides key techniques for ex situ and in situ investigation of clean energy materials and, hence, is an essential guide for researchers working on the structural analysis of advanced materials.

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Direct alcohol fuel cells (DAFCs), such as methanol and ethanol ones, are very promising advanced power systems that may considerably reduce dependence on fossil fuels and are, therefore, attracting increased attention worldwide. Nanostructured materials can improve the performance of the cathodes, anodes, and electrolytes of DAFCs. This book focuses on the most recent advances in the science and technology of nanostructured materials for direct alcohol fuel cells, including novel non-noble or low noble metal catalysts deposited on the graphene layer and metal-free doped carbon black for oxygen electroreduction reaction, Sn-based bimetallic and trimetallic nanoparticles for alcohol electro-oxidation reaction, and novel nanomaterials for promoting proton transfer in electrolytes. In addition, the book includes chapters from not only experimentalists but also computational chemists who have worked in the development of advanced power systems for decades.Illustrated throughout with excellent figures, this multidisciplinary work is not just a reference for researchers in chemistry and materials science, but a handy textbook for advanced undergraduate- and graduate-level students in nanoscience- and nanotechnology-related courses, especially those with an interest in developing novel materials for advanced power systems.

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These days, advanced multiscale hybrid materials are being produced in the industry, studied by universities, and used in several applications. Unlike for macromaterials, it is difficult to obtain the physical, mechanical, electrical, and thermal properties of nanomaterials because of the scale. Designers, however, must have knowledge of these properties to perform any finite element analysis or durability and damage tolerance analysis. This is the book that brings this knowledge within easy reach.What makes the book unique is the fact that its approach that combines multiscale multiphysics and statistical analysis with multiscale progressive failure analysis. The combination gives a very powerful tool for minimizing tests, improving accuracy, and understanding the effect of the statistical nature of materials, in addition to the mechanics of advanced multiscale materials, all the way to failure. The book focuses on obtaining valid mechanical properties of nanocomposite materials by accurate prediction and observed physical tests, as well as by evaluation of test anomalies of advanced multiscale nanocomposites containing nanoparticles of different shapes, such as chopped fiber, spherical, and platelet, in polymeric, ceramic, and metallic materials. The prediction capability covers delamination, fracture toughness, impact resistance, conductivity, and fire resistance of nanocomposites. The methodology employs a high-fidelity procedure backed with comparison of predictions with test data for various types of static, fatigue, dynamic, and crack growth problems. Using the proposed approach, a good correlation between the simulation and experimental data is established.

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The phenomenal success of nanostructures in various applications has led to the exploration of a plethora of novel nanomaterials. Nanoboron is no exception. Boron as material has the ability to form covalently bonded stable networks and finds use in a large variety of applications. This book provides a complete overview of the latest developments in the field of boron nanostructures. It starts with an introductory chapter on the fundamentals of boron chemistry, followed by chapters by experts devoted to discussions on boron nanoclusters, nanosheets, nanotubes, and nanowires, respectively. Applications of boron in nanomedicine are also discussed in wide detail.Very few titles covering Boron have surfaced to date; however, most of them are introductory text on boron chemistry and its properties along with couple of others covering specialized topics such as uses of boron in steel making, etc. This text provides state-of-the-art knowledge along with recent developments in boron nanostructures through succulent discussions.

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Magnetic nanoparticles appear naturally in rock magnetism together with a large distribution of sizes and shapes. They have numerous applications from nano-size magnetic memories to metamaterials for electromagnetic waves as well as biological applications such as nanosurgery with minimal traumatism. Their long-ranged size- and shape-dependent dipolar interactions provide numerous useful properties.This book describes the preparation as well as the magnetic properties of nanoparticles and also considers 2D dots, nearly spherical samples, elongated samples, and various assemblies of nanoparticles. The authors report the static magnetic structures and dynamic properties of these nanoparticles and the topological defects in 2D and 3D nanoparticles with new examples of S-shaped vortex or antivortex and of bent vortex or antivortex in 3D nanoparticles. The spectrum of magnetic excitations is shown to exhibit the occurrence of gaps, a key for magnonic metamaterial devices. Magnetic excited states are also considered with their coupling to nanoparticle elastic properties.

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Nanobiocatalysis has rapidly developed into a subarea of enzyme biotechnology. It combines the advances in nanotechnology that have generated nanoscale materials of different sizes, shapes, and physicochemical properties, and the excellent characteristics of biocatalysts into an innovative technology. This book provides an overview of the various relations between nanotechnology and biocatalysis. It discusses the fabrication and application of nanomaterials for the immobilization of enzymes used in the sustainable production of goods and chemicals. Nanosupports have several advantages compared with bulk solid materials because of their high surface area, which results in a significantly reduced mass transfer limitation and comparatively high enzyme loading. These characteristics are also of great use for applications in the fields of enzymatic biosensors, biofuel cells, bioelectronics, and photoelectrochemical analyte detection, where conductive nanomaterials improve the rate of electron transfer. The book also presents an overview of nanotoxicology and covers nanostructured enzyme catalysis in organic solvents and its potential application for biodiesel production, probing of enzymatic activity, and identification of enzyme functions of inorganic nanoparticles as enzyme mimics.

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