Search results for ""Author John Wiley"

Digitalization is a long socio-historic process in which all areas of society�s activities are reconfigured. In the first volume of Digitalization of Society and Socio-political Issues, there is an examination of the transformations linked to the development of digital platforms and social media which affect cultural and communicational industries. The book also analyzes the formation of Big Data, their algorithmic processing and the societal changes which result from them (social monitoring and control in particular). Through diverse critical reflections, it equally presents different ways that digital participates in relations of power and domination, and contributes to eventual emancipatory practices. Following on, the second volume examines the transformations that are linked to digital practices that affect the production, circulation and consumption of information, as well as new forms that are taken by social mobilizations. It treats several important issues in the digital era that are more likely to become the subject of public debates, among which one can include the renewed relationship between research and digital. Through diverse critical reflections, it equally presents different ways that digital participates in relations of power and domination, and contributes to eventual emancipatory practices.

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Digitalization is a long and constant sociohistoric process in which all areas of society�s activities are reconfigured. Digitalization of Society and Socio-political Issues 1 examines the transformations linked to the development of digital platforms and social media, which affect the cultural and communicational industries. It analyzes the formation of Big Data, their algorithmic processing and the societal changes which result (social monitoring and control in particular). Through critical views, it equally presents the various ways in which technology participates in relations of power and domination, and contributes to possible emancipatory practices.

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We are at a crucial time for the production and dissemination of knowledge – one in which the scientific community is questioning the nature of the digital humanities. Within this context, Learner Support in Online Learning Environments proposes, by taking into consideration the notion of assistance in a learning context, an original method of positioning digital resources for teachers, students and researchers in the humanities and social sciences. Questioning existing theoretical frameworks and prototypes, learner support in digital environments is presented as both a process and a result integrating a variety of resources. Some of these resources already exist, some may be adapted from existing objects and still others have yet to be imagined. The end goal is to facilitate both independent and group-based learning activities.

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In a context where climate change urgently requires us to alter our paradigms, this book explores the possibilities of cities that are both more energy efficient and more respectful of the environment. Based on the observation that urban planning has been detrimentally affected by the compartmentalization of knowledge and practices, this book is conceived as a dialog between transport and urban planning on the one hand, and between engineering and social science on the other. Systemic analysis and a historical approach, integrating the teachings of the last two centuries, constitute at the methodological level the framework in which this dialog unfolds. Based on examples of good practice, Transport and Town Planning identifies an effective set of levers of action and proposes an original method to guide and accompany urban transition with a large share of the initiative reserved for the actors concerned.

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This book demonstrates that our daily relations, like our most recognized institutions, are based on a symbolic foundation put in place by rituals. Rituals are present at every level of society and are an expression of the sacredness of society, as much as they are an expression of the cultures and eras that communicate through them.

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This book is centred about the Principle of virtual work and the related method for mechanical modelling. It aims at showing and enhancing the polyvalence and versatility of the virtual work approach in the mechanical modelling process. The virtual work statement is set as the principle at the root of a force modelling method that can be implemented on any geometrical description. After experimentally induced hypotheses have been made on the geometrical parameters that describe the concerned system and subsystems, the method provides a unifying framework for building up consistently associated force models where external and internal forces are introduced through their virtual rates of work. Systems described as three-dimensional, curvilinear or planar continua are considered: force models are established with the corresponding equations of motion; the validation process points out that enlarging the domain of relevance of the model for practical applications calls for an enrichment of the geometrical description that takes into account the underlying microstructure.

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This is the first book of a series aiming at setting the basics for energy engineering. This book presents the fundamentals of heat and mass transfer with a step-by-step approach, based on material and energy balances. While the topic of heat and mass transfer is an old subject, the way the book introduces the concepts, linking them strongly to the real world and to the present concerns, is particular. The scope of the different developments keeps in mind a practical energy engineering view.

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Using classification, diagrams and crystallography elements, we describe in this book the bonds in the crystals using the basic patterns. The use of various criteria such as ionicity character of the bonds, the use of hard sphere models, the Pauling rules and the spatial availability of ions all together make it possible to better understand the spatial organization of typical crystals. Through original representations, the structure and the nature of the bonds in binary crystals of MX- and MX2- types as well as the ternary crystals of the perovskite and spinel type are studied.

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Although most people are aware of the value of developing new energy technologies, the importance of assessing such technologies is only just beginning to be recognized in full. This book, illustrated by real-life examples, fulfils two main objectives. Firstly, it provides an in-depth summary of energy system evaluation methods, the result of decades of work in this area, for the use of researchers, engineers and anybody else interested in the energy sector. Secondly, the vicious cycle of neglect towards in situ evaluation is broken. This neglect is due to its unjust reputation for being “thankless work”: longwinded, expensive, difficult to exploit and undervalued. By scientifically organizing experience acquired over more than 30 years, Energy Transition highlights the considerable usefulness of the approach, not only economically, but also from a human standpoint.

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This book will teach you how to take advantage of the JavaScript language to process data provided on the Internet. Much attention is given to the main JavaScript backbone: prototype based objects, and functional capabilities, while common features (loops, etc.) are summarized in a few cheat-sheets. Only operational features are detailed through the coding of several applications -the second and largest part of the book-, on free-access datasets (e.g. World Bank). It includes: cartography (SVG or API's based), data-sheets access (via Ajax or Jsonp), video data and post-synchronization, and animation examples.

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"This standard assumes that the structure, after completion, is used as intended in the project and subject to planned inspection and maintenance to meet the expected project lifetime and to detect any unforeseen weakness or behavior" (EN 13670 §4.1) An important decision factor in the design of new structures and repairs to existing structures is the lifetime or expected service life. This concept, which is common for civil engineering works, has been extended to all engineering and building works by applying the European Structural Design Codes. This book tries to take stock of the inspection methodologies related to each type of civil engineering work, the various pathologies of concrete structures, and gives examples of the writing of reports.

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Instead of outsourcing tasks to providers using labor-intensive countries, libraries around the world increasingly appeal to the crowds of Internet users, making their relationship with users more collaborative . These internet users can be volunteers or paid, work consciously, unconsciously or in the form of games. They can provide the workforce, skills, knowledge or financial resources that libraries need in order to achieve unimaginable goals.

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Nowadays, tensors play a central role for the representation, mining, analysis, and fusion of multidimensional, multimodal, and heterogeneous big data in numerous fields. This set on Matrices and Tensors in Signal Processing aims at giving a self-contained and comprehensive presentation of various concepts and methods, starting from fundamental algebraic structures to advanced tensor-based applications, including recently developed tensor models and efficient algorithms for dimensionality reduction and parameter estimation. Although its title suggests an orientation towards signal processing, the results presented in this set will also be of use to readers interested in other disciplines. This first book provides an introduction to matrices and tensors of higher-order based on the structures of vector space and tensor space. Some standard algebraic structures are first described, with a focus on the hilbertian approach for signal representation, and function approximation based on Fourier series and orthogonal polynomial series. Matrices and hypermatrices associated with linear, bilinear and multilinear maps are more particularly studied. Some basic results are presented for block matrices. The notions of decomposition, rank, eigenvalue, singular value, and unfolding of a tensor are introduced, by emphasizing similarities and differences between matrices and tensors of higher-order.

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The aim of this book is the study of signals and deterministic systems, linear, time-invariant, finite dimensions and causal. A set of useful tools is selected for the automatic and signal processing and methods of representation of dynamic linear systems are exposed, and analysis of their behavior. Finally we discuss the estimation, identification and synthesis of control laws for the purpose of stabilization and regulation.

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“We do not know where Silicon Valley is really located”, Feldman writes, because these types of organization, when they are dynamic, are moving and fluid. Innovation and production ecosystems or clusters are proliferating today because they seem to be adapted to the demands of innovation, growth and employment. The process leading to their institutionalization escapes a summary analysis of the behavior triggered by monetary incentives or, at the very least, makes it richer. The relational aspect becomes predominant, the interactions between the participants testify to the difficulty of separating the geographical and social dimensions. In the most prominent American clusters, public/private linkages and the building of social links express the centrality of networks in the innovation process. The European vision seeks to articulate entrepreneurial discoveries with vertical public interventions. The competitiveness poles in France suffer from the fact that public choices seem to be torn between two contradictory objectives: efficiency and equity.

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Better known as the "predator-prey relationship," the consumer-resource relationship means the situation where a single species of organisms consumes for survival and reproduction. For example, Escherichia coli consumes glucose, cows consume grass, cheetahs consume baboons; these three very different situations, the first concerns the world of bacteria and the resource is a chemical species, the second concerns mammals and the resource is a plant, and in the final case the consumer and the resource are mammals, have in common the fact of consuming. In a chemostat, microorganisms generally consume (abiotic) minerals, but not always, bacteriophages consume bacteria that constitute a biotic resource. 'The Chemostat' book dealt only with the case of abiotic resources. Mathematically this amounts to replacing in the two equation system of the chemostat the decreasing function by a general increasing then decreasing function. This simple change has greatly enriched the theory. This book shows in this new framework the problem of competition for the same resource.

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In the automotive industry, a Control Engineer must design a unique control law that is then tested and validated on a single prototype with a level of reliability high enough to to meet a number of complex specifications on various systems. In order to do this, the Engineer uses an experimental iterative process (Trial and Error phase) which relies heavily on his or her experience. This book looks to optimise the methods for synthesising servo controllers ny making them more direct and thus quicker to design. This is achieved by calculating a final controller to directly tackle the high-end system specs.

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According to the NACFAM (National Council for Advanced Manufacturing, USA) Sustainable Manufacturing is defined "as the creation of manufactured products that use processes that are non-polluting, conserve energy and natural resources, and are economically sound and safe for employees, communities, and consumers." The book covers Sustainable Manufacturing techniques such as materials and manufacturing for renewable energies; clean manufacturing technology; ecological manufacturing; energy-efficient manufacturing; remanufacturing; recycling of materials; environmentally conscious design and manufacturing processes; sustainable advanced manufacturing systems; manufacturability in sustainable product design; education and training for sustainable manufacturing.

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This title is dedicated to energy storage, low emission technologies and energy management, with discussions on the future of nuclear energy, combined heat and power, using hydrogen as an energy vector and fuel cells, as well as chapters on energy saving and control of the demand for power.

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This book is the first of a series of volumes that cover the topic of aerospace actuators following a systems-based approach. This first volume provides general information on actuators and their reliability, and focuses on hydraulically supplied actuators. Emphasis is put on hydraulic power actuators as a technology that is used extensively for all aircraft, including newer aircraft. Currently, takeovers by major corporations of smaller companies in this field is threatening the expertise of aerospace hydraulics and has inevitably led to a loss of expertise. Further removal of hydraulics teaching in engineering degrees means there is a need to capitalize efforts in this field in order to move it forward as a means of providing safer, greener, cheaper and faster aerospace services. The topics covered in this set of books constitute a significant source of information for individuals and engineers seeking to learn more about aerospace hydraulics.

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Although the theory of operations management has been presented in many textbooks published in the last two decades, the subject of e-enabled operations management is rather short of easily accessible literature. The approach to operations management described in this book is unusual with respect to what is found in standard textbooks. Information and Communication Technologies (ICT) impact the ways firms are organised and managed, and as a consequence change the practical means used to conduct business operations. The features of this book are threefold. System approach to business modelling: Business activities, controlling functions and associated information systems are described within a coherent analytical system framework allowing a clear understanding of the various current control and costing concepts. Operations costing is not usually included in textbooks as part of operations management, but it should be. Cost targeting has become an integral part of good practice of business management. Validity of models: Apparently simple models are analyzed in depth. Students must be fully aware of the assumptions made when models are formulated and of their conditions of validity. Applying a model implies automatically that assumptions of a sort are taken for granted. Logistics, procurement and quality management: These three business functions are critical key success factors for managing e-enabled supply chains from suppliers to customers. That is why their main tools are introduced in this document.

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Quantum networks build on entanglement and quantum measurement to achieve tasks that are beyond the reach of classical systems. Using quantum effects, we can detect the presence of eavesdroppers, raise the sensitivity of scientific instruments such as telescopes, or teleport quantum data from one location to another. Long-distance entanglement can be used to execute important tasks such as Byzantine agreement and leader election in fewer rounds of communication than classical systems, improving the efficiency of operations that are critical in distributed systems.

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Generally a laser (light amplification by stimulated emission of radiation) is defined as “a device which uses a quantum mechanical effect, stimulated emission, to generate a coherent beam of light from a lasing medium of controlled purity, size, and shape”. Laser material processing represents a great number of methods, which are rapidly growing in current and different industrial applications as new alternatives to traditional manufacturing processes. Nowadays, the use of lasers in manufacturing is an emerging area with a wide variety of applications, for example, in electronics, molds and dies, and biomedical applications. The purpose of this book is to present a collection of examples illustrating the state of the art and research developments to lasers in manufacturing, covering laser rapid manufacturing, lasers in metal forming applications, laser forming of metal foams, mathematical modeling of laser drilling, thermal stress analysis, modeling and simulation of laser welding, and the use of lasers in surface engineering. This book can be used as a research book for a final undergraduate engineering course or as a subject on lasers in manufacturing at the postgraduate level. Also, this book can serve as a useful reference for academics, laser researchers, mechanical, manufacturing, materials or physics engineers, or professionals in any related modern manufacturing technology. Contents 1. Laser Rapid Manufacturing: Technology, Applications, Modeling and Future Prospects, Christ P. Paul, Pankaj Bhargava, Atul Kumar, Ayukt K. Pathak and Lalit M. Kukreja. 2. Lasers in Metal Forming Applications, Stephen A. Akinlabi, Mukul Shukla, Esther T. Akinlabi and Tshilidzi Marwala. 3. Laser Forming of Metal Foams, Fabrizio Quadrini, Denise Bellisario, Erica A. Squeo and Loredana Santo. 4. Mathematical Modeling of Laser Drilling, Maturose Suchatawat and Mohammad Sheikh. 5. Laser Cutting a Small Diameter Hole: Thermal Stress Analysis, Bekir S. Yilbas, Syed S. Akhtar and Omer Keles. 6. Modeling and Simulation of Laser Welding, Karuppudaiyar R. Balasabramanian, Krishnasamy Sankaranarayanasamy and Gangusami N. Buvanashekaran. 7. Lasers in Surface Engineering, Alberto H. Garrido, Rubén González, Modesto Cadenas, Chin-Pei Wang and Farshid Sadeghi.

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This series of five volumes proposes an integrated description of physical processes modeling used by scientific disciplines from meteorology to coastal morphodynamics. Volume 1 describes the physical processes and identifies the main measurement devices used to measure the main parameters that are indispensable to implement all these simulation tools. Volume 2 presents the different theories in an integrated approach: mathematical models as well as conceptual models, used by all disciplines to represent these processes. Volume 3 identifies the main numerical methods used in all these scientific fields to translate mathematical models into numerical tools. Volume 4 is composed of a series of case studies, dedicated to practical applications of these tools in engineering problems. To complete this presentation, volume 5 identifies and describes the modeling software in each discipline.

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This series of five volumes proposes an integrated description of physical processes modeling used by scientific disciplines from meteorology to coastal morphodynamics. Volume 1 describes the physical processes and identifies the main measurement devices used to measure the main parameters that are indispensable to implement all these simulation tools. Volume 2 presents the different theories in an integrated approach: mathematical models as well as conceptual models, used by all disciplines to represent these processes. Volume 3 identifies the main numerical methods used in all these scientific fields to translate mathematical models into numerical tools. Volume 4 is composed of a series of case studies, dedicated to practical applications of these tools in engineering problems. To complete this presentation, volume 5 identifies and describes the modeling software in each discipline.

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Capturing, recording and broadcasting the voice is often difficult. Many factors must be taken into account and achieving a true representation is much more complex than one might think. The capture devices such as the position of the singer(s) or narrator(s), the acoustics, atmosphere and equipment are just some of the physical aspects that need to be mastered. Then there is the passage through the analog or digital channel, which disrupts the audio signal, as well as the processes that are often required to enrich, improve or even transform the vocal timbre and tessitura. While in the past these processes were purely material, today digital technologies and software produce surprising results that every professional in recording and broadcasting should know how to master.Recording and Voice Processing 1 addresses some general theoretical concepts. A history of recording and the physiology of the vocal apparatus are detailed in order to give the reader an understanding of the fundamental aspects of the subject. This volume also includes an advanced study of microphones, addressing their characteristics and typologies. The acoustic environment and its treatment are also considered in terms of the location of the sound capture - whether in a home studio, recording studio, live or natural environment - in order to achieve a satisfactory sound recording.

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Due to their special properties, organic semiconductors enable the development of large-area, low-cost devices, paving the way for flexible and nomadic applications that advantageously replace those made with traditional semiconductors. In this second volume, we study the main applications of organic semiconductors, such as organic light-emitting diodes (OLEDs), solar cells (OPVs) and organic field-effect transistors (OFETs).The commercialization of these new devices is then discussed within the Brabec triangle framework, in which yield, stability and production costs are the key factors. We also address the environmental impact of organic devices for their future development. This book presents the application side of organic electronics from a technological, economic and environmental perspective. It is intended for researchers and students in university programs or engineering schools specializing in electronics, energy and materials.

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The great deltas of the globe have been threatened for several decades but their decline now appears to be inevitable; they are receding and losing the fertility that supports their tens of millions of inhabitants. Our deltas are victims of the dramatic deterioration in the volume of continental sediment brought by rivers to the oceans.By nature, deltas are fragile eco- and geological organisms. For centuries, they have been subject to human actions in the Mediterranean and European world, and today a deep crisis is affecting the great tropical deltas. A chapter is also devoted to concerns facing the Mississippi, an “aging delta of the new world”.Sedimentary Crisis at the Global Scale 2 discusses possible strategies to protect the deltas of the world – or at least adapt them and their dependencies to the changes they face. Several models are possible, including comprehensive protection (such as in the Netherlands) and cautious and respectful opening to the forces of the oceans in an environment-first perspective.

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Volume 3 begins with an introduction to which are added four chapters focused on modeling and flow simulation in an environment in 2 or 3 dimensions (2D or 3D). They deal with different cases taken from situations found in the field. A conclusion comes close this third book: The different software used in this third volume Computer simulation of discrete flows Mixed flow simulation Flows in 3D and the evacuation simulation Flows in 3D for conveying and storage The conclusion discusses the future developments of the software and their integration into society. At the end of each volume is a bibliography and a list of web links. There is also a glossary explaining some abbreviations, acronyms and some very specific terminology of logistics and operations research.

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Process Engineering, the science and art of transforming raw materials and energy into a vast array of commercial materials, was conceived at the end of the 19th Century. Its history in the role of the Process Industries has been quite honorable, and techniques and products have contributed to improve health, welfare and quality of life. Today, industrial enterprises, which are still a major source of wealth, have to deal with new challenges in a global world. They need to reconsider their strategy taking into account environmental constraints, social requirements, profit, competition, and resource depletion. “Systems thinking” is a prerequisite from process development at the lab level to good project management. New manufacturing concepts have to be considered, taking into account LCA, supply chain management, recycling, plant flexibility, continuous development, process intensification and innovation. This book combines experience from academia and industry in the field of industrialization, i.e. in all processes involved in the conversion of research into successful operations. Enterprises are facing major challenges in a world of fierce competition and globalization. Process engineering techniques provide Process Industries with the necessary tools to cope with these issues. The chapters of this book give a new approach to the management of technology, projects and manufacturing. Contents Part 1: The Company as of Today 1. The Industrial Company: its Purpose, History, Context, and its Tomorrow?, Jean-Pierre Dal Pont. 2. The Two Modes of Operation of the Company – Operational and Entrepreneurial, Jean-Pierre Dal Pont. 3. The Strategic Management of the Company: Industrial Aspects, Jean-Pierre Dal Pont. Part 2: Process Development and Industrialization 4. Chemical Engineering and Process Engineering, Jean-Pierre Dal Pont. 5. Foundations of Process Industrialization, Jean-François Joly. 6. The Industrialization Process: Preliminary Projects, Jean-Pierre Dal Pont and Michel Royer. 7. Lifecycle Analysis and Eco-Design: Innovation Tools for Sustainable Industrial Chemistry, Sylvain Caillol. 8. Methods for Design and Evaluation of Sustainable Processes and Industrial Systems, Catherine Azzaro-Pantel. 9. Project Management Techniques: Engineering, Jean-Pierre Dal Pont. Part 3: The Necessary Adaptation of the Company for the Future 10. Japanese Methods, Jean-Pierre Dal Pont. 11. Innovation in Chemical Engineering Industries, Oliver Potier and Mauricio Camargo. 12. The Place of Intensified Processes in the Plant of the Future, Laurent Falk. 13. Change Management, Jean-Pierre Dal Pont. 14. The Plant of the Future, Jean-Pierre Dal Pont.

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Neben der Methodenentwicklung ist die Optimierung bestehender Methoden eine zentrale Aufgabe im HPLC-Labor. Eine Aufgabe, die heute in immer kürzerer Zeit und kosteneffizient erledigt werden muss. Das Handbuch bietet eine fundierte Hilfe, um diese Herausforderung noch besser zu meistern. International renommierte Autoren wie John W. Dolan, Michael McBrien, Veronika R. Meyer, Uwe D. Neue, Lloyd R. Snyder oder Klaus K. Unger behandeln sowohl die allgemeinen Grundlagen und Strategien der Optimierung als auch die spezifischen Aspekte der unterschiedlichen Techniken wie RP-HPLC, NP-HPLC, Micro- und Nano-HPLC sowie der Kopplungstechniken wie LC-MS. Auch die richtige Säulenauswahl sowie Enantiomerentrennungen gehören zu den behandelten Themen. Die Autoren liefern konkrete, praktische Tipps ebenso wie relevante Hintergrundinformationen. Sie bieten darüber hinaus Einblicke in die Optimierungspraxis sieben international renommierter Firmen verschiedener Branchen. Einige Beiträge stellen die Anwendung gängiger Optimierungssoftware wie DryLab oder ChromSword dar. Das ganze wird abgerundet durch praxisnahe Berichte erfahrener Anwender aus den verschiedenen Anwendungsgebieten, inbesondere aus den Life Sciences, wie beispielsweise Proteomics oder Pharmaentwicklung. Alle Beiträge sind in einem auf das Wesentliche konzentrierten und anwendungsnahen Stil geschrieben. Der Aufbau des Buches mit abgeschlossenen Kapiteln erleichtert das gezielte Nachschlagen.

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The human specificity can be described by verticality/bipedalism, technique use, articulated language, high cognitive capacities, complex society at three levels: body, mind, social. In this book, is proposed an evolutionary process that make better understand how such humanity could have emerged in the long time (more than 6 million years). The process is based on a very early necessity to use technic for surviving correlated with neoteny which impulsed a darwinian evolutionary process, with four distinguished punctuation described as neotenizations.

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In 1905, Einstein's Annus Mirabilis, Albert Einstein made three discoveries concerning the foundations of nature which form the basis of his fame as a physicist. These revolutionary papers on the light-quantum hypothesis, Brownian motion, and special relativity, were published in the journal "Annalen der Physik". All three are now established as pillars of modern science and its applications in technology and are an indispensable part of the modern world. This volume presents some of the most significant original papers which Albert Einstein ever wrote. It includes the facsimiles of the three revolutionary papers of 1905. In addition it contains papers which show the consequences of the ground-breaking ideas of these seminal papers from E=mc² to the quantum theory of specific heats. It also features Einstein's first exposition of his new general theory of relativity. Introducing the original German papers the science historians Jürgen Renn (MPI for the History of Science, Berlin), David C. Cassidy (Hofstra University, Hempstead), Michel Janssen (University of Minnesota), and Robert Rynasiewicz (John Hopkins University) complement and comment the collection with topical articles.

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Richtig oder falsch? Moralisch oder unmoralisch? Das ist hier die Frage Wo ziehen wir die Linie zwischen richtig und falsch? Wo die zwischen gutem und schlechtem Handeln? Und wie positionierten sich Denker wie Immanuel Kant, John Stuart Mill und Thomas Hobbes zu diesem Thema? Christopher Panza und Adam Potthast nehmen Sie mit auf eine Erkundungsreise zu diesen scheinbar einfachen Fragen und den dazugehörigen, oftmals überraschend komplexen, Antworten. Sie verdeutlichen das Verhältnis von Wissenschaft und Religion zur Ethik, entfalten die Bedeutung der Goldenen Regel und vieles mehr. Dieses Buch ist daher Ihr idealer Begleiter, wenn Sie sich systematisch den vielschichtigen Aspekten der Ethik und den daraus resultierenden Fragen nähern möchten. Sie erfahren Welche Sicht die Tugendethik, die Prinzipien- und Vertrags-ethik, die utilitaristische und die feministische Ethik vertreten Welche Auswirkungen sie auf unser moralisches Verständnis haben Welch tiefgründigen Fragestellungen die Medizin-, Umwelt- und Sexualethik beschäftigen.

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Transformieren Sie Ihre Organisation mit Geschwindigkeit und Effizienz! Schrittweise Verbesserungen reichen nicht mehr aus, um Organisationen dabei zu helfen, die Komplexität, Unsicherheit und Volatilität der heutigen Welt zu bewältigen. In "Change" erforschen die Autoren John P. Kotter, Vanessa Akhtar und Gaurav Gupta, wie Sie nicht-lineare, dramatische Veränderungen in Ihrer Organisation meistern können. Sie werden die aufkommende "Wissenschaft des Wandels" entdecken, die uns lehrt, wie man Organisationen aufbaut - von Unternehmen bis hin zu Regierungen -, die sich schnell verändern und anpassen können. Im Buch erfahren Sie: - warum die Fähigkeit von Organisationen, mit Bedrohungen umzugehen und Chancen angesichts immer größerer Komplexität und Unsicherheit zu nutzen, ernsthaft in Frage gestellt wird. - detaillierte, evidenzbasierte und umsetzbare Lösungen für den Umgang mit institutionellem Widerstand gegen Veränderungen. - Fallstudien und Erfolgsgeschichten von Organisationen, die die Fähigkeit, sich schnell zu verändern, erfolgreich in ihre DNA eingebaut haben. - einen allgemeingültigen Ansatz, um die Ergebnisse verschiedener Veränderungsbemühungen dramatisch zu verbessern, einschließlich: Strategieumsetzung, digitale Transformation, Umstrukturierung und mehr. Kotters neuestes Buch ist perfekt für Manager, Führungskräfte und Leiter in Unternehmen aller Arten und Größen. Nicht nur für sie, sondern auch für andere Fachleute, die diese Organisationen betreuen, wird sich "Change" als wertvolle Bereicherung erweisen. Das Buch ist ideal für alle, die einen bewährten Ansatz für die Erreichung von schnellen, nachhaltigen und umfassenden Ergebnissen suchen.

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Medical Product Regulatory Affairs Hands-on guide through the jungle of medical regulatory affairs for every professional involved in bringing new products to market Based on a module prepared by the authors for an MSc course offered by the University of Limerick, Ireland, Medical Product Regulatory Affairs is a comprehensive and practical guide on how pharmaceutical and medical devices are regulated within the major global markets. The Second Edition builds on the success of the first with an even wider scope and full coverage of new EU regulations on the safe use of medical devices. Following a look at drug development, complete sections are devoted to national and EU regulatory issues, manufacturing license application and retention, and regulation in the USA. Other topics dealt with include CDER, CBER and marketing and manufacturing licenses, the ICH process and Good Laboratory/Clinical/ Manufacturing Practices. Medical Product Regulatory Affairs includes information on: Aims and structure of regulation, covering purpose and principles of regulation, national and EU legislative processes, and pharmacopeia Regulatory strategy, covering product development and manufacturing, market vigilance, quality assurance systems, personnel, and documentation Drug discovery and development, covering prescription status, physical properties, therapeutic use, and drug discovery, development, and delivery Non-clinical studies, covering non-clinical study objectives and timing, pharmacological and pharmacodynamic studies, and bioavailability and bioequivalence Clinical trials, covering trial protocol, monitoring of trials, trial master files, and FDA communications The wide coverage of different product types and the main global markets makes Medical Product Regulatory Affairs ideal for training courses on regulatory affairs in academia and industry. It is also a valuable reference for pharmacologists, bioengineers, pharma engineers, and students in pharmacy to familiarize themselves with the topic.

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In this beautiful book of photographs and short essays, some of Appalachia’s best-known writers profile each other and the place they call home. Edited by Bloodroot novelist Amy Greene and her husband Trent Thomson, this book also features Wendell Berry, Lee Smith, Crystal Wilkinson, Ron Rash, Wiley Cash, Silas House, Jason Kyle Howard, Adriana Trigiani, and others. Part photo book, part essay collection, and all praise for the mountains and valleys of the region, this book collects some of the region’s greatest literary treasures for a generation of readers.

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In this beautiful book of photographs and short essays, some of Appalachia’s best-known writers profile each other and the place they call home. Edited by Bloodroot novelist Amy Greene and her husband Trent Thomson, this book also features Wendell Berry, Lee Smith, Crystal Wilkinson, Ron Rash, Wiley Cash, Silas House, Jason Kyle Howard, Adriana Trigiani, and others. Part photo book, part essay collection, and all praise for the mountains and valleys of the region, this book collects some of the region’s greatest literary treasures for a generation of readers.

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This book brings together a total of 48 contributions (including 5 keynote papers) which were presented at the 2nd International Workshop on the Application of X-ray CT for Geomaterials (GeoX 2006) held in Aussois, France, on 4-7 October, 2006. The contributions cover a wide range of topics, from fundamental characterization of material behavior to applications in geotechnical and geoenvironmental engineering. Recent advances of X-ray technology, hardware and software are also discussed. As such, this will be valuable reading for anyone interested in the application of X-ray CT to geomaterials from both fundamental and applied perspectives.

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This book presents the recent work regarding the different approaches developed in the framework of the joint optimization of intelligent maintenance and production strategies. The originality of these strategies is that they take various constraints into account, including production management, subcontracting environmental degradation, inspection and product quality.

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A promising long-term evolution of surgery relies on intracorporeal microrobotics. This book reviews the physical and methodological principles, and the scientific challenges to be tackled to design and control such robots. Three orders of magnitude will be considered, justified by the class of problems encountered and solutions implemented to manipulate objects and reach targets within the body: millimetric, sub-millimetric in the 10- 100 micrometer range, then in the 1-10 micrometer range. The most prominent devices and prototypes of the state of the art will be described to illustrate the benefit that can be expected for surgeons and patients. Future developments nanorobotics will also be discussed.

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The rushed development of information and communication technologies and their impact on the world of learning in the last decade have profoundly changed the paradigms, scenarios and values at all levels of education. The professionalization of tools and practices, in addition to the consolidation of academic and practical knowledge, has been a major continuing issue throughout these years. The annual conferences of the largest European professional community in distance and e-learning have been setting the landmarks in this process. The selection from this unique knowledge pool demonstrates the deepening and consolidation of knowledge and experience. This book presents the developments in the field of open, distance and e-learning, through new technologies, methodologies and tools, which have profoundly changed the paradigms, scenarios and values at all levels of education over the last decade.

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This series in three volumes considers maps as constructions resulting from a number of successive transformations and stages integrated in a logical reasoning and an order of choices. Volume 1 introduces the basis of thematic cartography; the map is regarded as a construct due to transformation processes. Volume 2 focuses on the impact of the quantitative revolution, partially related to the advent of the computer age, on thematic cartography. Volume 3 is exclusively focused on the new approaches on thematic cartography offered by the three successive revolutions affecting the discipline: digital, multimedia and the Internet.

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Nearly all solids are compised of grains. However most studies treat materials as a continious solid. The book applies analysis used on loose granular materials to dense grainular materials. This title’s main focus is devoted to static or dynamic loadings applied to dense materials, although rapid flows and widely dispersed media are also mentioned briefly. Three essential areas are covered: Local variable analysis: Contact forces, displacements and rotations, orientation of contacting particles and fabric tensors are all examples of local variables. Their statistical distributions, such as spatial distribution and possible localization, are analyzed, taking into account experimental results or numerical simulations. Change of scales procedures: Also known as “homogenization techniques”, these procedures make it possible to construct continuum laws to be used in a continuum mechanics approach or performing smaller scale analyses. Numerical modeling: Several methods designed to calculate approximate solutions of dynamical equations together with unilateral contact and frictional laws are presented, including molecular dynamics, the distinct element method and non-smooth contact dynamics. Numerical examples are given and the quality of numerical approximations is discussed.

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This title presents a large variety of models and algorithms dedicated to the resource-constrained project scheduling problem (RCPSP), which aims at scheduling at minimal duration a set of activities subject to precedence constraints and limited resource availabilities. In the first part, the standard variant of RCPSP is presented and analyzed as a combinatorial optimization problem. Constraint programming and integer linear programming formulations are given. Relaxations based on these formulations and also on related scheduling problems are presented. Exact methods and heuristics are surveyed. Computational experiments, aiming at providing an empirical insight on the difficulty of the problem, are provided. The second part of the book focuses on several other variants of the RCPSP and on their solution methods. Each variant takes account of real-life characteristics which are not considered in the standard version, such as possible interruptions of activities, production and consumption of resources, cost-based approaches and uncertainty considerations. The last part presents industrial case studies where the RCPSP plays a central part. Applications are presented in various domains such as assembly shop and rolling ingots production scheduling, project management in information technology companies and instruction scheduling for VLIW processor architectures.

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This volume contains contributions from speakers at the 4th International Symposium on Finite Volumes for Complex Applications, held in Marrakech, Morocco, in July 2005. The subject of these papers ranges from theoretical and numerical results to physical applications. Topics covered include: Theoretical and numerical results • theoretical foundation • convergence • new finite volume schemes • adaptivity • higher order discretization and parallelization Physical applications • multiphase flow and flows through porous media • turbulent flows • shallow water problems • stiff source terms • cryogenic applications • medical and biological applications • image processing Papers on Industrial codes, as well as interdisciplinary approaches are also included in these proceedings.

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This book focuses on the challenges of competition in television broadcasting markets. How is the evolution from a two-sided market to platform economics reshaping competition in television broadcasting? How are new market dynamics changing competition for content creation and acquisition and the revenue streams? Will content remain king? Or will new competitive dynamics undermine the sustainable creation of high quality content, especially in small media markets?

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This book is dedicated to metaheuristics as applied to vehicle routing problems. Several implementations are given as illustrative examples, along with applications to several typical vehicle routing problems. As a first step, a general presentation intends to make the reader more familiar with the related field of logistics and combinatorial optimization. This preamble is completed with a description of significant heuristic methods classically used to provide feasible solutions quickly, and local improvement moves widely used to search for enhanced solutions. The overview of these fundamentals allows appreciating the core of the work devoted to an analysis of metaheuristic methods for vehicle routing problems. Those methods are exposed according to their feature of working either on a sequence of single solutions, or on a set of solutions, or even by hybridizing metaheuristic approaches with others kind of methods.

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