Search results for ""taylor francis inc""

In the critical work of maintaining power plant machinery, operating difficulties with centrifugal pumps will inevitably occur because of the essential requirement for electric power plants to operate at all times throughout the year. The root causes and solutions for pump failure comprise major areas of study for engineers in seeking the highest availability of electricity-generating units, extending time between major machinery overhauls and providing early detection of potential failure modes well in advance of machine degradation.This guide for engineers provides a comprehensive overview of the fundamentals of centrifugal pumps, addressing the range of pump operating problems encountered in both fossil and nuclear power plants. The book is divided into three sequential parts: Part I - Primer on Centrifugal Pumps, Part II -Power Plant Centrifugal Pump Applications, and Part III - Trouble-Shooting Case Studies. Employing effective research models developed through years of experience, the author draws on an extensive range of scholarship that covers the detrimental impact of power plant pump failures on overall plant performance, as well as the preventative measures that aid in successful pump maintenance. After covering the performance and components of centrifugal pumps, operating failure modes are covered both for fossil and nuclear power plants. This is followed by the presentation of several power plant pump troubleshooting case studies. The text also walks readers through the various other industrial applications of centrifugal pumps, as in their use within petrochemical plants and in ocean vessel propulsion systems. Recognizing the warning signs of specific impending pump failure modes is essential to minimizing the financial costs of dealing with pump operating problems. To this end, the author lays out a range of theoretical models and relevant examples in support of the essential work of power plant pump use and maintenance:

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Based on the author’s introductory course at the University of Oregon, Explorations in Computing: An Introduction to Computer Science focuses on the fundamental idea of computation and offers insight into how computation is used to solve a variety of interesting and important real-world problems. Taking an active learning approach, the text encourages students to explore computing ideas by running programs and testing them on different inputs. It also features illustrations by Phil Foglio, winner of the 2009 and 2010 Hugo Award for Best Graphic Novel.Classroom-Tested MaterialThe first four chapters introduce key concepts, such as algorithms and scalability, and hone practical lab skills for creating and using objects. In the remaining chapters, the author covers "divide and conquer" as a problem solving strategy, the role of data structures, issues related to encoding data, computer architecture, random numbers, challenges for natural language processing, computer simulation, and genetic algorithms. Through a series of interactive projects in each chapter, students can experiment with one or more algorithms that illustrate the main topic. Requiring no prior experience with programming, these projects show students how algorithms provide computational solutions to real-world problems. Web ResourceThe book’s website at www.cs.uoregon.edu/eic presents numerous ancillaries. The lab manual offers step-by-step instructions for installing Ruby and the RubyLabs gem with Windows XP, Mac OS X, and Linux. The manual includes tips for editing programs and running commands in a terminal emulator. The site also provides online documentation of all the modules in the RubyLabs gem. Once the gem is installed, the documentation can be read locally by a web browser.After working through the in-depth examples in this textbook, students will gain a better overall understanding of what computer science is about and how computer scientists think about problems.

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Despite being recognized and fought against over countless centuries, human viral pathogens continue to cause major public health problems worldwide—killing millions of people and costing billions of dollars in medical care and lost productivity each year. With contributions from specialists in their respective areas of viral pathogen research, Molecular Detection of Human Viral Pathogens provides a reliable reference on molecular detection and identification of major human viral pathogens.Each chapter briefly reviews the classification, epidemiology, clinical features, and diagnosis of one related viral pathogen or a group of them. The clinical sample collection and preparation procedures are outlined, and a selection of representative stepwise molecular detection protocols is covered. The chapters conclude with a discussion on further research requirements relating to improved diagnosis. With its judicious selection of streamlined, ready-to-use protocols for major human viral pathogens—including commercial kits—Molecular Detection of Human Viral Pathogens is an indispensable tool for medical, veterinary, and industrial laboratory scientists involved in virus determination.

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In today’s increasingly competitive business environment, organizations must be able to adapt to the ever-changing business landscape where traditional business concepts no longer ensure success. The future will be driven by value and competing ideas—creating an environment where old alignments and equations will be replaced by a global network of projects and brand equity can evaporate quickly. Scale business relationships or perish is becoming the new mantra. Written by a team of authors from the world's largest software outsourcer, Web-Based and Traditional Outsourcing explains how to leverage the Web to effectively manage and deploy people, resources, and competencies—regardless of their location. It introduces ground-breaking business models and frameworks that add significant value to outsourcing. This cutting-edge reference: Integrates sourcing, acquisition, payment, and sales into a single end-to-end solution Addresses outsourced project management, as well as the offer and acceptance of technology services Details how to reduce costs and improve delivery times in software projects through reuse Explains risk sharing, co-ownership, win-win business approaches, and equity-based contracts Examining emerging trends and the future of outsourcing, the text provides authoritative insights into what are becoming the new ways of doing business. The authors supply the enterprise-wide vision of corporate capabilities needed to address contemporary outsourcing issues and include helpful tools for evaluating offshore vendors and determining the best location for your infrastructure needs.

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The hydrological sciences typically present grey or fuzzy information, making them quite messy and a choice challenge for fuzzy logic application. Providing readers with the first book to cover fuzzy logic modeling as it relates to water science, the author takes an approach that incorporates verbal expert views and other parameters that allow him to eschew the use of mathematics. The book’s first seven chapters expose the fuzzy logic principles, processes and design for a fruitful inference system with many hydrological examples. The last two chapters present the use of those principles in larger scale hydrological scales within the hydrological cycle.

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Here to bring back the pride, confidence, and jobs that "Made in the U.S.A." once generated—Keeping Your Business in the U.S.A.: Profit Globally While Operating Locally shows American enterprises how to survive and prosper while keeping their manufacturing base within the United States. It tells the stories of three manufacturing companies that have been able to buck the outsourcing trend and achieve overwhelming success while keeping jobs in the States.Using case studies, the book illustrates each company’s story from the day it started. It examines the successes, failures, lessons learned, and methods used by each company to achieve and sustain success. The authors integrate nearly a century of combined experience to compare the different business strategies, make key observations, and provide helpful tips for duplicating the recipes that led to these companies’ overwhelming success.Debunking the myth that U.S. manufacturers can’t compete with cheap labor countries, the authors detail seven recipes they have found to be common denominators among the successful companies they have encountered. These manufacturing veterans provide you with simple but effective ingredients, the recipes, and the way of thinking needed to re-establish "Made in the U.S.A." as the beacon of progress and quality it once was. Watch co-author Paul Piechota discuss how this book can benefit your business.

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The Handbook of Photonics for Biomedical Science analyzes achievements, new trends, and perspectives of photonics in its application to biomedicine. With contributions from world-renowned experts in the field, the handbook describes advanced biophotonics methods and techniques intensively developed in recent years.Addressing the latest problems in biomedical optics and biophotonics, the book discusses optical and terahertz spectroscopy and imaging methods for biomedical diagnostics based on the interaction of coherent, polarized, and acoustically modulated radiation with tissues and cells. It covers modalities of nonlinear spectroscopic microscopies, photonic technologies for therapy and surgery, and nanoparticle photonic technologies for cancer treatment and UV radiation protection. The text also elucidates the advanced spectroscopy and imaging of normal and pathological tissues. This comprehensive handbook represents the next step in contemporary biophotonics advances. By collecting recently published information scattered in the literature, the book enables researchers, engineers, and medical doctors to become familiar with major, state-of-the-art results in biophotonics science and technology.

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With in depth coverage of multifaceted problems and their solutions, this book reviews nano/micro studies of different coatings, bioengineering, lubricants and additives, system problems including reliability assessment and new testing and diagnosis approaches in various dimensions. The book presents original investigations and studies in the area of mechanical engineering and industrial tribology. It is useful for engineers and technologist of heavy industry, students, research engineers/scientists, academicians and others who grapple with the complex problems of testing of engineering components and tribology for multifaceted research for further developments.

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Despite generations of change and recent, rapid developments in gas dynamics and hypersonic theory, relevant literature has yet to catch up, so those in the field are generally forced to rely on dated monographs to make educated decisions that reflect present-day science. Written by preeminent Russian aerospace researcher Vladimir V. Lunev, Real Gas Flows with High Velocities reflects the most current concepts of high-velocity gas dynamics. For those in aviation and aerospace, this is a vital methodical revitalization and reassessment of real gas flows with regard to the physical and gasdynamic effects related to high-velocity flight, and, in particular, the entry of bodies into the atmosphere of Earth and other planets.Much more than just a manual on gas physics, this book: Analyzes fundamental challenges associated with super- and subsonic flight Describes the physical properties of gas mixtures and their associated high-temperature processes from the phenomenological standpoint Explores use of computational mathematics and equipment to simplify previously unsolvable problems of inviscid and viscous gas dynamics Explains why numerical methods remain inferior to analytical methods for creating a conceptual understanding of gas dynamic and other physical problems Avoiding older, cumbersome approximate methods, this reference outlines the general patterns and features of typical flows and how real gas affects them. Referencing simple, analytically treatable examples, similarity laws, and asymptotic analysis, the author omits superfluous explanation of reasoning. This valuable reference summarizes general theory of super- and subsonic flow and uses practical problems to develop a solid understanding of modern real-gas flows and high-velocity gas dynamics.

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An evolving, living organic/inorganic covering, soil is in dynamic equilibrium with the atmosphere above, the biosphere within, and the geology below. It acts as an anchor for roots, a purveyor of water and nutrients, a residence for a vast community of microorganisms and animals, a sanitizer of the environment, and a source of raw materials for construction and manufacturing. To develop lasting solutions to the challenges of balanced use and stewardship of the Earth, we require a fundamental understanding of soilfrom its elastic, porous three-phase system to its components, processes, and reactions.Now in two volumes, Handbook of Soil Sciences, Second Edition is a comprehensive and cohesive reference on the discipline of soil science. It contains definitive descriptions of each major area in the discipline, including fundamental principles, appropriate methods to measure each property, variations in properties in different soils throughout the world,

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Ion-Pair Chromatography (IPC) is a rapidly evolving method for difficult analyses of organic and inorganic ions and ionogenic, neutral, and zwitterionic compounds. The possibilities for this technology continue to grow as novel ion-pair reagents and strategies are introduced at an accelerated level. Compensating for a dearth in the literature, Ion-Pair Chromatography and Related Techniques details the basics and the evolution of this established and easily tunable technique and explains its influence on similar methods.Theoretical modeling to applicationProviding a thorough exploration of the multiplicity of interactions involved in an IPC system, this book emphasizes the progress from theoretical modeling to application. It explores the practical potential of IPC in the life science, medicine, pharmacology, forensic, food, and environmental sectors. It examines the upgrade of column technology and instrumentation to improve data quality and to increase sample throughput. The book also compares IPC to other instrumental methods of analysis and discusses the rising importance of the ion-pair concept in different analytical techniques.Future endeavorsIPC has the potential to have lasting impact in the field of chromatography. Distilling the knowledge gained from preeminent research, this volume is a critical resource that is destined to stimulate future endeavors by separation scientists working in the area of high performance liquid chromatography.

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Definitive Treatment of the Numerical Simulation of Bioheat Transfer and Fluid FlowMotivated by the upwelling of current interest in subjects critical to human health, Advances in Numerical Heat Transfer, Volume 3 presents the latest information on bioheat and biofluid flow. Like its predecessors, this volume assembles a team of renowned international researchers who cover both fundamentals and applications. It explores ingenious modeling techniques and innovative numerical simulation for solving problems in biomedical engineering.The text begins with the modeling of thermal transport by perfusion within the framework of the porous-media theory. It goes on to review other perfusion models, different forms of the bioheat equation for several thermal therapies, and thermal transport in individual blood vessels. The book then describes thermal methods of tumor detection and treatment as well as issues of blood heating and cooling during lengthy surgeries. It also discusses how the enhancement of heat conduction in tumor tissue by intruded nanoparticles improves the efficacy of thermal destruction of the tumor. The final chapters focus on whole-body thermal models, issues concerning the thermal treatment of cancer, and a case study on the thermal ablation of an enlarged prostate.

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The analysis of drugs and their metabolites in biological media are now expected to routinely achieve ± 20% accuracy in the ng/mL concentration level. Therefore, the availability and the selection of quality ion-pairs designating the analytes and their isotopically labeled analogs (ILAs) are important considerations in achieving the accuracy of quantitation results. Assisting scientists with this process, Quantitation and Mass Spectrometric Data of Drugs and Isotopically Labeled Analogs provides an extremely valuable reference for labs involved in the analysis of therapeutic and abused drugs.Part One of this comprehensive volume illustrates approaches, mechanisms, and challenges pertaining to the use of isotopic analogs as internal standards for drug quantitation. The second section is a systematic compilation of full-scan mass spectra of drugs and their analogs, as parent compounds and as derivatives resulting from various chemical derivatization approaches, commonly encountered in today’s labs. Based on the mass spectra data presented in the second section, Part Three provides corresponding tables of ion-pairs which can potentially be adapted to designate the drugs and their isotopic analogs in the analytical processes. Relative quality of these ion-pairs (cross-contribution to the intensity of these ions by their isotopic analogs) is included in these tables.With more than 1500 full-scan mass spectra and quick access data tables, this text represents the authors’ years of work compiling mass spectra of the many chemical derivatization forms of drugs, their metabolites, and their isotopically labeled counterparts. The unparalleled scope of this compilation makes it a critical one-stop reference for those involved in drug analyses of biological specimens and interpretation of results.

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This paper tries to give an overview on technologies using fibrous materials for contributing to environmental and resource matters. The technologies for water treatment include bio-reactive treatment system using membrane hollow fibre, desalination using Ro hollow fibre, purification of water work using UF or MF hollow fibre, purification of recycled water using photo-catalyst fibre, and oil removal systems using micro-fibre nonwoven. Removal system for incineration dust using bag filter, and removal system for toxic gas and solvent recovery using activated carbon fibre are typical examples for air cleaning. Fibrous materials are also effectively utilized for saving and production of energy and resources. Their application examples are electrode and separator for battery, and composite reinforcements for high pressure CNG vessel and wind turbine blade. The lightening transport vehicles using fibre reinforced composites have now become a big issue.

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In recent years, high-density DNA microarrays have revolutionized biomedical research and drug discovery efforts by the pharmaceutical industry. Their efficacy in identifying and prioritizing drug targets based on their ability to confirm a large number of gene expression measurements in parallel has become a key element in drug discovery. Microarray Innovations: Technology and Experimentation examines the incredibly powerful nature of array technology and the ways in which it can be applied to understanding the genomic basis of disease. Explores a myriad of applications in use todayThis volume explores recent innovations in the microarray field and tracks the evolution of the major platforms currently used. The international panel of contributors presents a survey of the past five years’ research and advancements in microarray methods and applications and their usage in drug discovery and biomedical research. The contributions discuss improvements in automation (array fabrication and hybridization), new substrates for printing arrays, platform comparisons and contrasts, experimental design, and data normalization and mining schemes. They also review epigenomic array studies, electronic microarrays, comparative genomic hybridization, microRNA arrays, and mutational analyzes. In addition, the book provides coverage of important clinical diagnostic arrays, protein arrays, and neuroscience applications.Examines improved methodologiesAs microarrays have evolved steadily over time from archetypical in-house complementary DNA (cDNA) arrays to robust commercial oligonucleotide platforms, there has been a migration to higher density biochips with increasing content and better analytical methodologies. This compendium summarizes the vast advances that have been made in this technology, highlighting the supreme advantages of microarray-based appro

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Humanoid robots are highly sophisticated machines equipped with human-like sensory and motor capabilities. Today we are on the verge of a new era of rapid transformations in both science and engineering—one that brings together technological advancements in a way that will accelerate both neuroscience and robotics. Humanoid Robotics and Neuroscience: Science, Engineering and Society presents the contributions of prominent scientists who explore key aspects of the further potential of these systems.Topics include: Neuroscientific research findings on dexterous robotic hand control Humanoid vision and how understanding the structure of the human eye can lead to improvements in artificial vision Humanoid locomotion, motor control, and the learning of motor skills Cognitive elements of humanoid robots, including the neuroscientific aspects of imitation and development The impact of robots on society and the potential for developing new systems and devices to benefit humans The use of humanoid robotics can help us develop a greater scientific understanding of humans, leading to the design of better engineered systems and machines for society. This book assembles the work of scientists on the cutting edge of robotic research who demonstrate the vast possibilities in this field of research.

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Optofluidics is an emerging field that involves the use of fluids to modify optical properties and the use of optical devices to detect flowing media. Ultimately, its value is highly dependent on the successful integration of photonic integrated circuits with microfluidic or nanofluidic systems. Handbook of Optofluidics provides a snapshot of the state of the field, captures current trends, and gives insight into the technology of tomorrow, which will enable researchers to tackle challenges and opportunities that it can uniquely answer.Divided into three sections, this comprehensive resource begins by introducing the scientific foundations that contribute to optofluidics. It details the connections to related research areas and reveals the scientific influences currently shaping the design and function of optofluidic systems. It provides brief reviews of those established fields from which optofluidics has evolved, putting special emphasis on how they currently intersect.This introductory material provides a basis for understanding the chapters that follow. The second section explores the synthesis of fundamental concepts to create novel devices, specifically those with optical properties that are manipulated by fluids. A main theme that runs through this part is the dynamic reconfigurability made possible by flowing and reshaping fluids. The final section looks to future applications of the field, presenting recent developments in particle detection and manipulation primarily being developed for biosensing and biomedical applications. Enhanced by thematic connections throughout the chapters that help define the field, this volume is a concise reference for the growing optofluidics community and is poised to provide a stepping stone for continued research in an area that holds promise for a myriad of applications.

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While a quick response can save you in a time of crisis, avoiding a crisis remains the best defense. When dealing with complex industrial systems, it has become increasingly obvious that preparedness requires a sophisticated understanding of human factors as they relate to the functional characteristics of socio-technology systems. Edited by industrial safety expert Erik Hollnagel and featuring commentary from leaders in the field, Safer Complex Industrial Environments: A Human Factors Approach examines the latest research on the contemporary human factors approach and methods currently in practice. Drawing on examples mainly from the nuclear industry, the book presents a contemporary view on human factors in complex industrial systems. The contributors contrast the traditional view of human factors as a liability with the contemporary view that recognizes human factor as also an asset without which the safe and efficient performance of complex industrial systems would be impossible. It describes how this view has developed in parallel to the increasing complexity and intractability of socio-technical systems and partly as a consequence of that. The book also demonstrates how this duality of the human factor can be reconciled by recognizing that the human and organizational functions that can be the cause of adverse events are also the very foundation for safety.Building on this, the book introduces theories and methods that can be used to describe human and collective performance in a complex socio-technical environment. It explores how contemporary human factors can be used to go beyond failure analysis to actively make complex industrial environments safer.

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While modern computational methods can provide us with the wave function of a molecule in numerical form, most computer programs lack the sophisticated tools needed to extract chemical concepts from these wave functions. Saving researchers vast time and potential confusion, this volume collects and organizes those validated tools currently scattered throughout the literature and details their application. It provides immediate access for those needing to calculate such critical factors as bond order and valence indices, and atomic and diatomic contributions to molecular energy. Supporting material is available for download from the authors' continually updated website.

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These proceedings from the 2008 NSTI Nanotech conference provide the most prestigious forum in the world for leading nano scientists. The papers from the conference have been compiled into three volumes to create the most authoritative and comprehensive compendium available across all of nanotechnology. Including the latest information on industrial development, investments, and ventures, each volume explores cutting-edge research and applications. Volume II covers various aspects of cancer treatment, biomarkers, nanoparticles, drug delivery systems, nanobiotechnology, nanomedicine, nanoneurology, sensors, and soft nanotechnology.

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As a pioneer in Lean improvement methods, Jim Martin was among the first to suggest that truly successful Lean initiatives are those applied across every facet of an organization, not just on the shop floor. Building on this concept, Martin demonstrates that one of the most effective ways to implement operational improvements across an organization is to approach it through the resource that permeates every facet of a modern organization—information technology.Measuring and Improving Performance: Information Technology Applications in Lean Systems explains how the effective use of Lean project management methodologies can increase the productivity of information system deployment in service and manufacturing organizations. Starting with an overview of Lean and agile project management principles, the author walks readers through the implementation of Lean practices across key aspects of IT systems. Created to provide Lean and Six Sigma practitioners with a clear understanding of the important concepts related to the creation and modification of software to support process improvement activities across Lean systems, this reference book: Details how to apply Lean principles to IT systems on a global scale Explains how to design IT systems capable of meeting evolving customer needs and expectations Covers several project management methods including agile project management (APM), agile unified process (AUP), SCRUM, extreme programming (EP) Identifies the operational issues that can help project execution and those that can hinder it Complete with roadmaps and checklists, this book will help busy IT and Lean professionals discover more efficient ways to monitor business activity, gather business intelligence, manage and analyze business processes, and ultimately—increase overall operational efficiency.

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Widely used in medical research, pharmaceutical and fine chemicals industries, biological and physical sciences, and security and environmental agencies, mass spectrometry techniques are continually under development. In Practical Aspects of Trapped Ion Mass Spectrometry: Volume V, Applications of Ion Trapping Devices, an international panel of authors presents a world-wide view of the practical aspects of recent progress using trapped ion devices.In contrast to previous texts, which have concentrated generally on a single or limited range of ion trapping techniques, a key feature of this compilation of contributions is its coverage of all the ion trapping techniques currently in use. Spanning sixteen chapters, the text examines: Ion/neutral and ion/ion reactions Structural characterization of proteins and peptides using quadrupole ion trap mass spectrometry, Fourier transform – ion cyclotron resonance (FT-ICR) mass spectrometry, and traveling wave ion mobility mass spectrometry Ion spectroscopy and electron diffraction Conformational analysis of protein isobaric charge states Practical examples of trapped-ion technology that reflect the wide diversity of applications of trapped-ion devices This text is the first detailed account of the application of new and established mass spectrometric techniques utilizing trapped or confined ions for prolonged investigation and increased sensitivity. Each chapter contains complete references and utilizes a consistent format and writing style, with all terms, acronyms, procedures, and equations thoroughly explained. The strong editorial input to the diverse sections enables readers to readily appreciate the commonalities of topics ranging from theory of instrument operation to proteins, flavonoids, atomic clocks, and single ion mass spectrometry.

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Thanks to advances in electronic archiving of biodiversity data and the digitization of climate and other geophysical data, a new era in biogeography, functional ecology, and evolutionary ecology has begun. In Data Mining for Global Trends in Mountain Biodiversity, Christian Korner, Eva M. Spehn, and a team of experts from the Global Mountain Biodiversity Assessment of DIVERSITAS explore two of the hottest subjects in science and technology: biodiversity and data mining. They demonstrate how to harness the scientific power of biological databases for furthering ecological and evolutionary theory. Expert contributors address two aspects of the Global Mountain Biodiversity Assessment. They cover how to link biodiversity data with geophysical data and how to use biodiversity data to substantiate evolutionary and ecological theory. The text provides different methodological approaches and examples of successful mining of geo-referenced data in mountain regions on various scales. It includes: Elevational and latitudinal gradients in plant diversity E-mining trends in diversity of Lepidoptera, beetles, and birds Niche modeling to explain past trends and predict future trends in mountain biodiversity Sharing biodiversity data with the Global Biodiversity Information Facility Using electronic databases opens ways to manage biodiversity in a sustainable fashion, test evolutionary and ecological theories, and measure the impact of climate change on various species and its effect on conservation efforts. The information and examples presented in this book can stimulate the creative use of archive data to answer old questions with new tools, and advance knowledge and understanding of mountain biodiversity worldwide. The book highlights the benefits of and the continuing need for an increase in the amount and quality of georeferenced data provided online in order to meet the challenges of global change.

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As healthcare becomes more complex, the integration of all members of the team becomes even more important. Part of this integration requires that all team members have a grasp of the fundamentals of the medical and surgical treatments they are involved in. Written specifically for paramedical professionals who support doctors and nurses, Clinical Procedures for Medical Technology Specialists presents a clear and concise description of the more common diagnostic and treatment procedures used in current medical care. While a great many texts describe medical and surgical procedures, there are few, if any, aimed at the large, diverse group of professionals who directly support the medical system. Moreover, these sources tend to have more detail than is required for a paramedical professional. Carefully organized in an encyclopedic format that allows easy access to just the right amount of information, this book supplies nonclinical members of the modern integrated healthcare team with a more complete perspective of the clinical experiences of the clients of the system — the patients.

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Industrially developing countries have the largest populations, the highest levels of poverty, poor health, and illiteracy, and the greatest need for improvement in working conditions. And as the marketplace and the workforce goes increasingly global, accountability with regard to the abuse of cheap labor in developing countries is becoming an issue. Presenting a global view of the state of ergonomics in industrially developing countries (IDCs), Ergonomics in Developing Regions: Needs and Applications identifies problems, offers solutions, and explores costs and benefits. It defines the steps that can be taken to close the gap between working conditions in affluent and deprived nations.The book highlights the plight of millions of laborers and the poor working conditions pertaining to industrially less developed countries where the working environment mirrors the socio-economic deprivation of the people. Woven throughout the 34 chapters of this book is the tenet that good ergonomics is good economics. The chapters include examples of low-cost interventions at the work place in IDCs. The contributors discuss the ripple effect of ergonomics beyond the workplace to the betterment of life in general for the huge workforce in IDCs around the world. They focus on work-site problems and ergonomic solutions in developing regions around the globe, covering work conducted in Asia, Africa, South America, Russia, and China. Examining the factors unique to IDCs, leading ergonomists provide insights as to how sustainable progress is achievable in the developing world. They demonstrate the need for a more inclusive macro approach, citing managerial input essential for sustainable progress. With a panel of authors that reflects the multidisciplinary nature of the field, this book chronicles the nuances of differences in aim, practice, and outcome when ergonomists tackle Developing World problems from a Developing World perspective.

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The International Police Executive Symposium (IPES, www.ipes.info) coordinates annual international conferences to evaluate critical issues in policing and recommend practical solutions to law enforcement executives deployed across the globe. Drawn from the 2005 proceedings hosted by the Czech Republic in Prague, Effective Crime Reduction Strategies: International Perspectives contains contributions from the renowned criminal justice and law enforcement professionals who gathered at this elite annual meeting. Dedicated to continued reduction in crime through local and global response, these international experts share effective crime-fighting principles and tried and proven best practices.Thoroughly revised and updated since the initial proceedings, the reports in this volume are divided into six sections which explore a host of essential topics: Critical Issues in European Law Enforcement: Highlights efforts in Hungary, Austria, and Norway to revise policies and organizational structures to meet the demands of developing events and political pressures Contemporary Concerns: Policing in the United States and Canada: Analyzes the impact of international terrorism and transnational crime on police work Paradigm Shifts: Policing as Democracy Evolves: Evaluates the success of democratic reforms in South Africa, Brazil, Argentina, Nigeria, and Cameroon Revising Traditional Law Enforcement in Asia to Meet Contemporary Demands: Describes how counterterrorism, cultural ideology, and transnational criminal influence affects the traditional nature of policing in New Zealand, Turkey, Indonesia, and Thailand The Positive Influence of Unionization on Police Professionalism: Addresses the impact of police associations on management decision-making and policy development in the United States, Canada, New Zealand, and South Africa Significant Issues Facing Twenty-First Century Law Enforcement: Focuses on counterterrorism, border and transnational criminality, the measurement of police effectiveness, and the investigation of juvenile crime Supplemented with select papers considered for the official journal of the IPES, this volume represents a thoroughly comparative approach to the challenges police executives face in the 21st century. Exploring a wide range of issues impacting how law enforcement professionals fight crime, experts from virtually all regions of the globe engage in discourse that is destined to shape future policing worldwide.

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Written by recognized leaders in this dynamic and rapidly expanding field, Indium Nitride and Related Alloys provides a clear and comprehensive summary of the present state of knowledge in indium nitride (InN) research. It elucidates and clarifies the often confusing and contradictory scientific literature to provide valuable and rigorous insight into the structural, optical, and electronic properties of this quickly emerging semiconductor material and its related alloys. Drawing from both theoretical and experimental perspectives, it provides a thorough review of all data since 2001 when the band gap of InN was identified as 0.7 eV. The superior transport and optical properties of InN and its alloys offer tremendous potential for a wide range of device applications, including high-efficiency solar cells and chemical sensors. Indeed, the now established narrow band gap nature of InN means that the InGaN alloys cover the entire solar spectrum and InAlN alloys span from the infrared to the ultraviolet. However, with unsolved problems including high free electron density, difficulty in characterizing p-type doping, and the lack of a lattice-matched substrate, indium nitride remains perhaps the least understood III-V semiconductor. Covering the epitaxial growth, experimental characterization, theoretical understanding, and device potential of this semiconductor and its alloys, this book is essential reading for both established researchers and those new to the field.

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Although the amount of research on copper amine oxidases has grown rapidly and substantially in the past decade, the field unfortunately suffers from lack of cohesion and significant confusion surrounds aspects as simple as confirmation of enzyme identities. This book describes the structure of the enzymes, the role of copper, and of the unusual cofactor 6-hydroxydopa quinine derived from a posttranslational modification of a tyrosine residue. It also covers the differences of between AOs from bacteria, plants, and mammals. Finally, the text examines the importance of this ubiquitous class of enzymes in physiology and in metabolism of biogenic amines.

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Uses Computational Tools to Simulate Endocrine Disruption PhenomenaEndocrine Disruption Modeling provides a practical overview of the current approaches for modeling endocrine activity and the related potential adverse effects they may induce on environmental and human health. Based on the extensive research of an international panel of contributors from industry, academia, and regulatory agencies, this is the first book devoted to using computer tools to better understand and simulate the multifaceted aspects of endocrine disruption in humans and wildlife. Explores Diverse Modeling Techniques and ApplicationsThis up-to-date resource focuses on xenobiotics that are accidentally released into the environment with the potential to disturb the normal functioning of the endocrine system of invertebrates and vertebrates but also on the specific agro-chemistry design of chemicals that take control of insect endocrine systems. A comprehensive research reference, Endocrine Disruption Modeling provides a collection of computational strategies to model these structurally diverse chemicals. It concludes with a review of the available e-resources in the field, rounding out the book’s task-oriented approach to future EDC discovery.Endocrine Disruption Modeling is the first book in the QSAR in Environmental and Health Sciences series (James Devillers, j.devillers@ctis.fr).

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In this, the post-genomic age, our knowledge of biological systems continues to expand and progress. As the research becomes more focused, so too does the data. Genomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we begin to unravel the complex mysteries of neurological diseases that less than a generation ago seemed opaque to our inquiries, if not altogether intractable.Edited by Dr. Oscar Alzate, Neuroproteomics is the newest volume in the CRC Press Frontiers of Neuroscience Series. With an extensive background in mathematics and physics, Dr. Alzate exemplifies the newest generation of biological systems researchers. He organizes research and data contributed from all across the world to present an overview of neuroproteomics that is practical and progressive.Bolstered by each new discovery, researchers employing multiple methods of inquiry gain a deeper understanding of the key biological problems related to brain function, brain structure, and the complexity of the nervous system. This in turn is leading to new understanding about diseases of neurological deficit such as Parkinson’s and Alzheimer’s.Approaches discussed in the book include mass spectrometry, electrophoresis, chromatography, surface plasmon resonance, protein arrays, immunoblotting, computational proteomics, and molecular imaging. Writing about their own work, leading researchers detail the principles, approaches, and difficulties of the various techniques, demonstrating the questions that neuroproteomics can answer and those it raises.New challenges wait, not the least of which is the identification of potential methods to regulate the structures and functions of key protein interaction networks. Ultimately, those building on the foundation presented here will advance

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An Easy-to-Use Research Tool for Algorithm Testing and DevelopmentBefore the SeqAn project, there was clearly a lack of available implementations in sequence analysis, even for standard tasks. Implementations of needed algorithmic components were either unavailable or hard to access in third-party monolithic software products. Addressing these concerns, the developers of SeqAn created a comprehensive, easy-to-use, open source C++ library of efficient algorithms and data structures for the analysis of biological sequences. Written by the founders of this project, Biological Sequence Analysis Using the SeqAn C++ Library covers the SeqAn library, its documentation, and the supporting infrastructure.The first part of the book describes the general library design. It introduces biological sequence analysis problems, discusses the benefit of using software libraries, summarizes the design principles and goals of SeqAn, details the main programming techniques used in SeqAn, and demonstrates the application of these techniques in various examples. Focusing on the components provided by SeqAn, the second part explores basic functionality, sequence data structures, alignments, pattern and motif searching, string indices, and graphs. The last part illustrates applications of SeqAn to genome alignment, consensus sequence in assembly projects, suffix array construction, and more.This handy book describes a user-friendly library of efficient data types and algorithms for sequence analysis in computational biology. SeqAn enables not only the implementation of new algorithms, but also the sound analysis and comparison of existing algorithms.Visit SeqAn for more information.

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Exploring the implementation of participatory, multistakeholder, and transdisciplinary ecosystem health research, Integrated Assessment of Health and Sustainability of Agroecosystems combines the latest theories in complexity and management with practical tools and approaches for sustainable rural development research. Although the text focuses on smallholder farming communities in the central highlands of Kenya, the material discussed can be—and has been—effectively applied to agroecosystems in many other parts of the world.After showing how the agroecosystem health framework was successfully adapted in a smallholder-dominated agroecosystem, the book integrates participatory methods, systems analyses, pulse process models, and soft systems methods in an open-ended, adaptive R&D process. It then looks at how to use correspondence analysis to refine a research-based suite of indicators and analyze data obtained using indicators. Incorporating the authors’ pioneering work in the ecosystem health field, this book demonstrates the potential of the agroecosystem health paradigm as a framework in the decision-making processes of agricultural communities in a tropical highlands area.

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Spurred on by extensive research in recent years, organic semiconductors are now used in an array of areas, such as organic light emitting diodes (OLEDs), photovoltaics, and other optoelectronics. In all of these novel applications, the photoexcitations in organic semiconductors play a vital role. Exploring the early stages of photoexcitations that follow photon absorption, Ultrafast Dynamics and Laser Action of Organic Semiconductors presents the latest research investigations on photoexcitation ultrafast dynamics and laser action in pi-conjugated polymer films, solutions, and microcavities.In the first few chapters, the book examines the interplay of charge (polarons) and neutral (excitons) photoexcitations in pi-conjugated polymers, oligomers, and molecular crystals in the time domain of 100 fs–2 ns. Summarizing the state of the art in lasing, the final chapters introduce the phenomenon of laser action in organics and cover the latest optoelectronic applications that use lasing based on a variety of cavities, such as distributed feedback-type cavity.With contributions from a host of renowned international experts, this book explores the underlying processes in both existing and potential organic optoelectronic applications. It provides a broad overview of the scientific debate in the field of photophysics in organic semiconductors.

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Although the Trefftz finite element method (FEM) has become a powerful computational tool in the analysis of plane elasticity, thin and thick plate bending, Poisson’s equation, heat conduction, and piezoelectric materials, there are few books that offer a comprehensive computer programming treatment of the subject. Collecting results scattered in the literature, MATLAB® and C Programming for Trefftz Finite Element Methods provides the detailed MATLAB® and C programming processes in applications of the Trefftz FEM to potential and elastic problems.The book begins with an introduction to the hybrid-Trefftz (HT) FEM that covers basic concepts and general element formulations of the method. It then concentrates on both the essentials and subroutines of MATLAB and C programming. The next few chapters present applications of T-elements to potential problems and linear plane elasticity, discuss how to solve body force in elasticity through radial basis functions, and examine how special purpose functions can be constructed. The final chapter explores advanced topics, such as the construction of Trefftz p-elements, dimensionless transformation, and an alternative formulation to HT FEM. Unifying the computer programming aspects of the Trefftz FEM, this book will stimulate the development and application of this novel method in many facets of practical engineering.

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Since the publication of the first edition, the field has changed dramatically. Scientists can now explicitly consider 3D features in quantitative structure-activity relationship (QSAR) studies and often have the 3D structure of the macromolecular target to guide the 3D QSAR. Improvements in computer hardware and software have also made the methods more accessible to scientists. Taking these developments into account, Quantitative Drug Design: A Critical Introduction, Second Edition shows scientists how to apply QSAR techniques at a state-of-the-art level.New to the Second Edition A new chapter on methods that identify the 3D conformations to use for 3D QSAR New discussions on partial least squares, multidimensional scaling, clustering, support vector machines, kNN potency prediction, and recursive partitioning Expanded case studies that include the results of data that has been re-analyzed using newer methods A new case study on the discovery of novel dopaminergics with pharmacophore mapping and CoMFA A new case study on the application of CoMFA to series in which the 3D structure of the ligand-protein complex is known Based on the author’s four decades of experience in all areas of ligand-based computer-assisted drug design, this invaluable book describes how to transform ligand structure-activity relationships into models that predict the potency or activity/inactivity of new molecules. It will help you avoid traps when dealing with quantitative drug design.

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Although chemists, biochemists, biologists, and material scientists are often interested in using nonlinear optical techniques for characterizing their samples, they seldom have the necessary background to exploit these methods. Designed for nonspecialists, Second-Order Nonlinear Optical Characterization Techniques: An Introduction focuses on the potential of second-order nonlinear optics as a powerful characterization tool. Avoiding extensive mathematical details, this multidisciplinary book does not require a background in advanced mathematics or physics. After introducing linear optics from the perspective of polarizability and linear susceptibility, the authors cover incoherent second-harmonic generation. They then deal with the study of surfaces and interfaces, exploiting the intrinsic surface sensitivity of second-harmonic generation and sum-frequency generation. The final chapter discusses second-order imaging techniques, including confocal microscopy and two-photon excited fluorescence microscopy.Accessible to a wide range of scientists, this concise book stresses the reliability of nonlinear optical processes for probing surfaces and interfaces. Drawing on the insight offered in the text, scientists from many disciplines can now clearly understand and use second-order nonlinear optical methods.

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Covers the Fundamentals of Chiral Separation, Available Chiral Selectors, and Numerous Applications of Chiral Separation by Capillary ElectrophoresisSince the 1980s, modern analytical tools have enabled capillary electrophoresis to become a standard part of the chemist’s toolkit. With contributions from international experts, Chiral Separations by Capillary Electrophoresis provides a general overview of the principles of chiral separation by capillary electrophoresis and the different chiral selectors available.The book discusses the most important as well as several new chiral selectors used in capillary electrophoresis. It reviews recent pharmaceutical and biomedical applications and explores novel techniques, such as capillary electrophoresis coupled to mass spectrometry and microchip technology. The book also examines the quantitative aspects of capillary electrophoresis, the possibilities of capillary electrochromatography, and the various chiral columns available.Capillary electrophoresis has proven to be an effective tool for chiral separation. This book explains how this technique can be used in the separation of molecules, offering insight into both existing and emerging applications.

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This unique new text delivers a solid foundation for understanding the role of genomics in human health and in advances that promise to help improve the quality of human life. Unlike other works that focus mainly on toxicogenomic techniques, Genomics presents a thorough overview of the field in four major sections: 1) fundamentals of genes and genome structure, function, expression, variations, and genomic technology platforms; 2) applications of genomics in drug discovery and drug development, safety evaluation, genomic database maintenance, mining, and analysis, food safety monitoring, and translational toxicogenomics; 3) how regulatory agencies such as the FDA and EPA use genomic data in their safety evaluation; and 4) a summary of the current state and the future prospect of the science of genomics.With an international perspective and practical case studies, Genomics is the first resource to present essential discussion of theory and application for: eukaryotic genomes epigenomics translational genomics and biomarker development

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Optimize Your Chemical DatabaseDesign and Use of Relational Databases in Chemistry helps programmers and users improve their ability to search and manipulate chemical structures and information, especially when using chemical database "cartridges". It illustrates how the organizational, data integrity, and extensibility properties of relational databases are best utilized when working with chemical information.The author facilitates an understanding of existing relational database schemas and shows how to design new schemas that contain tables of data and chemical structures. By using database extension cartridges, he provides methods to properly store and search chemical structures. He explains how to download and install a fully functioning database using free, open-source chemical extension cartridges within PostgreSQL. The author also discusses how to access a database on a computer network using both new and existing applications.Through examples of good database design, this book shows you that relational databases are the best way to store, search, and operate on chemical information.

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Highlighting the importance of transportation to a country’s infrastructure and survival, Transportation Systems Security presents the strategic and practical considerations involved in the implementation of physical, procedural, and managerial safeguards required to keep all modes of transportation up and running during an actual or potential disaster. Structured in an easy cognitive fashion, the book begins with a basic introduction providing terms and definitions. It describes both physical and information system layouts and defines who controls what parts of the process, how far control is extended, and who oversees controls within the system. Building on this foundation, subsequent chapters discuss problems such as the need for a more defined “domain-based” approach when threats, assets, vulnerabilities, and safeguards are not under local control. The book describes and refines the concepts of criticality, impact, and consequence as they relate to the assignation of value for personnel, assets, facilities, information and activities in terms of how they might support performance. By comparing continuity of operations planning (COOP) to business continuity planning (BCP), the book presents security measures as a value-added benefit rather than a hindrance to business and introduces the notion of certification, accreditation, and licensure. It demonstrates safeguards that layer outward from the entity and across the system with the ability to prevent, detect, and notify, as well as respond to and recover from a crisis. Emphasizing the sharing of information and methods, the book encourages security to become an integrated component within the system, not just imposed on top of it. It takes a holistic approach to the transportation infrastructure, introducing the concept of fragility and the measurable factors involved, and including a 20 page questionnaire to help managers determine their company’s fragility in terms of transportation security.

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Estuaries in every country exemplify the same paradox — they are among the most productive ecosystems and also among the most impacted by anthropogenic activities. And although estuarine biodiversity is key to the ecological and economic health of coastal regions, estuaries are exposed to toxic effluents transported by rivers from remote and nearby conurbations and industrial and agricultural concerns, putting them at risk. Increased attention to environmental issues highlights the fragility and importance of estuaries and brings to the forefront the need for an up-to-date assessment of techniques.Environmental Assessment of Estuarine Ecosystems: A Case Study describes a comparative, multidisciplinary ecotoxicological study of two contrasting estuaries in France. Based on the results of this study, the book presents generalizations about how different techniques might be applied and interpreted in future, similar studies assessing the ecotoxicological status of these vital coastal systems. With contributions from international experts, this reference covers all aspects of estuaries from the physiological to the economical. It introduces the state-of-the-art science required to investigate ecotoxicological problems in many estuaries all over the world.Although carefully focused on a specific region, this book covers a broad range of environmental issues and solutions, demonstrating how various pieces of information can be integrated into a sound assessment. Understanding the observations about this region and the techniques used for its assessment provide a benchmark for assessing, remediating, and applying new developments to other estuaries.

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Discover the Applicability, Benefits, and Potential of New Technologies As advances in algorithms and computer technology have bolstered the digital signal processing capabilities of real-time sonar, radar, and non-invasive medical diagnostics systems, cutting-edge military and defense research has established conceptual similarities in these areas. Now civilian enterprises can use government innovations to facilitate optimal functionality of complex real-time systems. Advanced Signal Processing details a cost-efficient generic processing structure that exploits these commonalities to benefit commercial applications. Learn from a Renowned Defense Scientist, Researcher, and InnovatorThe author preserves the mathematical focus and key information from the first edition that provided invaluable coverage of topics including adaptive systems, advanced beamformers, and volume visualization methods in medicine. Integrating the best features of non-linear and conventional algorithms and explaining their application in PC-based architectures, this text contains new data on: Advances in biometrics, image segmentation, registration, and fusion techniques for 3D/4D ultrasound, CT, and MRI Fully digital 3D/ (4D: 3D+time) ultrasound system technology, computing architecture requirements, and relevant implementation issues State-of-the-art non-invasive medical procedures, non-destructive 3D tomography imaging and biometrics, and monitoring of vital signs Cardiac motion correction in multi-slice X-ray CT imaging Space-time adaptive processing and detection of targets interference-intense backgrounds comprised of clutter and jamming With its detailed explanation of adaptive, synthetic-aperture, and fusion-processing schemes with near-instantaneous convergence in 2-D and 3-D sensors (including planar, circular, cylindrical, and spherical arrays), the quality and illustration of this text’s concepts and techniques will make it a favored reference.

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Two-phase nano- and micro-thermal control device research is now proving relevant to a growing range of modern applications, including those in cryogenics, thermal engineering, MEMS, and aerospace engineering. Until now, researchers have lacked a definitive resource that provides a complete review of micro- and nano-scale evaporative heat and mass transfer in capillaries-porous structures. Transport Phenomena in Capillary-Porous Structures and Heat Pipes covers the latest experiemental research efforts in two-phase thermal control technology research and development. The book covers vaporization heat transfer and hydrodynamic processes occurring in capillary channels and porous structures—paying particular attention to the physical mechanisms of these phenomena. Extensive experimental research activities on unique film and photo materials of boiling inside slits, capillaries, and capillary-porous structures are reviewed. By providing a complete record of research in the field, this volume gives researchers, engineers, and practitioners working on vaporization heat transfer and hydrodynamic processes the findings needed to avoid unnecessary experimental efforts, and will help further the development of this dynamic area of research.

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Urban development and migration from rural to urban areas are impacting prime agricultural land and natural landscapes, particularly in the less developed countries. These phenomena will persist and require serious study by those monitoring global environmental change. To address this need, various models have been devised to analyze urbanization and the physical, socioeconomic, and institutional factors impacting urban development. The most promising and rapidly developing of these paradigms take advantage of new Geographical Information System (GIS) technology. Modelling Urban Development with Geographical Information Systems and Cellular Automata presents one such cutting-edge model that is more than just predictive. It describes how the model simulates the urbanization process, and it provides theoretical context to promote understanding. Starting with a practical overview of the modelling techniques used in urban development research, the author focuses on the cellular automata model and its greatest strength – the incorporation of fuzzy set and fuzzy logic approaches through which urban development can be viewed as a spatially and temporally continuous process. Real-Life Application to Develop Future Planning Methods The text describes a landmark study underway, in which the fuzzy constrained cellular automata model has been implemented in a GIS environment to simulate urban development in Sydney, Australia. Featuring a survey of associated research and a geographical database for the Sydney simulation, this book answers many general "what if" questions for urban planners and details a new approach that they can adapt to their own testing and evaluation needs. This modeling method will provide researchers and planners with the means to not just predict population trends, but to better prepare for their consequences.

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Featuring hundreds of illustrations and references, this volume in the third edition of the Circuits and Filters Handbook, provides the latest information on analog and VLSI circuits, omitting extensive theory and proofs in favor of numerous examples throughout each chapter. The first part of the text focuses on analog integrated circuits, presenting up-to-date knowledge on monolithic device models, analog circuit cells, high performance analog circuits, RF communication circuits, and PLL circuits. In the second half of the book, well-known contributors offer the latest findings on VLSI circuits, including digital systems, data converters, and systolic arrays.

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In the U.S. alone, severe food-related allergic reactions account for an estimated 30,000 emergency room visits and 150 deaths per year – unsettling statistics for food product developers and manufacturers who are charged with ensuring food safety and quality throughout the entire farm-to-table production chain. Providing the clear-cut information necessary to conduct an effective allergen risk analysis, Chemical and Biological Properties of Food Allergens comprehensively examines the chemical, analytical, technological, and medical aspects of food allergies and the growing problem of cross-contact contamination during product processing.With contributions from an international team of research specialists, the book explains the basic mechanisms of allergenic reactions in humans, the molecular background of these mechanisms, and the problems of food tolerance and intolerance. It also discusses the issues related to common treatments of food allergies and the narrow groups into which they are categorized. Covering the most important recognized allergens in the U.S. and the EU, this resource also explores cutting-edge technological and biotechnological ways to lower the immuno-reactive and allergenic properties of foods. Chemical and Biological Properties of Food Allergens evaluates the current research literature in a concise format – a must for food product developers and biochemists.

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Highlighting latest advances in genetics and biochemistry, the completely revised Third Edition reviews the field from basic science, clinical, epidemiological, and regulatory perspectives. Contributions from top opinion leaders in the field bring together developments in molecular embryology and cell biology as they apply to problems in developmental toxicology. It covers testing of pharmaceutical and environmental agents and interpretation of developmental toxicology data, highlighting mathematical and statistical techniques, as well as the effects of toxic exposure on the functional development of various organs.The relationship between maternal and developmental toxicology is examined, in addition to current techniques for studying chemical disposition, metabolism, and placental transfer. Close attention is given to the regulatory aspects of testing and risk assessment. Pre- and postconceptional clinical care and genetic factors in clinical developmental toxicology are also discussed.Key topics include: the roles of apoptosis and signal transduction pathways in normal and abnormal development the role of epigenetic changes in development the role of nutrition and individual susceptibility the utility of bioinformatics global and targeted gene expression changes

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Industrial Safety and Health for Goods and Materials Services focuses on the safety requirements of the wholesale and retail trades, including warehousing. This detailed text describes the hazards associated with chemicals, compressed gases, and fire. In addition to discussing the ergonomics behind hand tools, ladders, machine guarding, material handling, and industrial trucks, the book: Addresses interventions and preventive approaches to help ensure a safe workplace Uses real-world examples and relevant illustrations Provides guidance on removal, delimiting, and mitigation of safety and health hazards Includes safety checklists and other tools for immediate use Identifies energy source exposures, potential hazards, and applicable regulations This resource provides a comprehensive review of applicable safety standards that impact these industries, and addresses how to work with OSHA to comply with its regulations. This text is a valuable reference for promoting safety in the workplace, and every manager in these fields would benefit from a copy.

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