Search results for ""Academia""

Transport economics and policy analysis is a field which has seen major advances in methodology in recent decades. The transport sector has many unique characteristics - non-storability, economies of scale and scope, indivisibilities and the extensive production of positive and negative externalities that need careful consideration in any analysis. The aim of this Handbook is to provide an overview of the essential research methods with illustrations of how they are applied in practice.The book is divided into six sections - transport costs, externalities, transport demand, pricing and investment, deregulation and privatisation, and transport policy impacts. Each section comprises several chapters, divided by mode of transport or other relevant factor.Some of the unique features include: a comprehensive overview of methods used in transport economics and policy analysis from leading researchers in the field up-to-date methodology for analyzing transport costs and demand examples of how to value the full range of externalities of transport, including both costs and benefits guidance on how to assess the impact of privatisation and (de)regulation, with examples from local public transport, rail and air identification of the relevant factors involved in transport pricing, including roads, public transport, ports and airports an analysis of the neglected topic of equity in transport. This illustrative overview of research methods will be essential to researchers, students and practitioners in academia, government and business.Contributors: J. Bates, O. Betancor, B. de Borger, T. Fowkes, J. Holmgren, J. Owen Jansson, G. de Jong, G. Lindberg, H. Link, R. Liu, A. Ljungberg, A.D. May, H. Meersman, S. Morrison, C. Nash, J.-E. Nilsson, J. de Dios Ortuzar, J. Preston, S. Proost, L.I. Rizzi, W. Rothengatter, G. de Rus, S. Shepherd, A. Smith, J. Stanley, J. Stanley, S. Pettersen Strandenes, D. Van de Velde, E. Van de Voorde, R. Vickerman, P. Wheat, M. Wolanski

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As scientists and technologists discover how to engineer matter at the nanoscale in increasingly sophisticated ways, conventional approaches to ensuring safe use are being brought into question. Nanotechnologies are challenging traditional regulatory regimes; but they are also prompting new thinking on developing and using emerging technologies safely. In this Handbook, leading international authors from industry, government, non-governmental organisations and academia examine the complex and often controversial regulatory challenges presented by nanotechnologies. Across several disciplinary boundaries, they explore how the future regulatory landscape may evolve. From the Europe Union to the United States, workplaces to personal products, and statutory instruments through to softer approaches, it is clear that considerable vigilance will be needed in governing these powerful and novel technologies. To succeed, society will need new thinking, new partnerships and new mechanisms to balance the benefits of these technologies against their possible downsides. Anything less will prompt cries of illegitimacy and potentially compromise a promising new realm of technology innovation.This Handbook draws on contributions from leading nanotechnology regulation scholars around the globe. It goes beyond articulating how certain nanotechnologies are currently regulated and the significance of existing regulatory gaps, to assessing how the future regulatory landscape may evolve. As well as considering potential legislative responses that could be employed by governments, the Handbook examines a range of other options available to stakeholders. The Handbook employs new and innovative lenses through which to view these regulatory challenges and by adopting an in-depth, systematic and whole-of-life-approach, synergistically combines contributions from many countries, many fields and many disciplines. Informative and insightful, it presents thought-provoking and stimulating perspectives on the coming nano-age and on how we as citizens will govern its future.

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This new, revised, and expanded edition of the popular Academic’s Handbook is an essential guide for those planning or beginning an academic career. Faculty members, administrators, and professionals with experience at all levels of higher education offer candid, practical advice to help beginning academics understand matters including:— The different kinds of institutions of higher learning and expectations of faculty at each.— The advantages and disadvantages of teaching at four-year colleges instead of research universities.— The ins and outs of the job market.— Alternatives to tenure-track, research-oriented positions.— Salary and benefits.— The tenure system.— Pedagogy in both large lecture courses and small, discussion-based seminars.— The difficulties facing women and minorities within academia.— Corporations, foundations, and the federal government as potential sources of research funds.— The challenges of faculty mentoring.— The impact of technology on contemporary teaching and learning.— Different types of publishers and the publishing process at university presses.— The modern research library.— The structure of university governance.— The role of departments within the university.With the inclusion of eight new chapters, this edition of The Academic’s Handbook is designed to ease the transition from graduate school to a well-rounded and rewarding career.Contributors. Judith K. Argon, Louis J. Budd, Ronald R. Butters, Norman L. Christensen, Joel Colton, Paul L. Conway, John G. Cross, Fred E. Crossland, Cathy N. Davidson, A. Leigh DeNeef, Beth A. Eastlick, Matthew W. Finkin, Jerry G. Gaff, Edie N. Goldenberg, Craufurd D. Goodwin, Stanley M. Hauerwas, Deborah L. Jakubs, L. Gregory Jones, Nellie Y. McKay, Patrick M. Murphy, Elizabeth Studley Nathans, A. Kenneth Pye, Zachary B. Robbins, Anne Firor Scott, Sudhir Shetty, Samuel Schuman, Philip Stewart, Boyd R. Strain, Emily Toth, P. Aarne Vesilind, Judith S. White, Henry M. Wilbur, Ken Wissoker

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After decades in which American popular culture dominated global media and markets, Japanese popular culture—primarily manga and anime, but also toys, card and video games, and fashion—has exploded into a worldwide phenomenon. From Pokémon and the Power Rangers to Paranoia Agent and Princess Mononoke, Japanese popular culture is consumed by an eager and exponentially increasing audience of youths, teenagers, and adults. Mechademia, a new annual edited by Frenchy Lunning, begins an innovative and fresh conversation among scholars, critics, and fans about the complexity of art forms like Superflat, manga, and anime. The inaugural volume, Mechademia 1 engages the rise of Japanese popular culture through game design, fashion, graphic design, commercial packaging, character creation, and fan culture. Promoting dynamic ways of thinking, along with state-of-the-art graphic design and a wealth of images, this cutting-edge work opens new doors between academia and fandom.The premiere issue features the interactive worlds that anime and manga have created, including the origins of cosplay (the manga and anime costume subculture), Superflat, forgotten images from a founding manga artist, video game interactivity, the nature of anime fandom in America, and the globalization of manga. Contributors: Anne Allison, Duke U; William L. Benzon; Christopher Bolton, Williams College; Vern L. Bullough, California State U, Northridge; Martha Cornog; Patrick Drazen; Marc Hairston; Mari Kotani; Thomas LaMarre; Antonia Levi, Portland State U; Thomas Looser, NYU; Susan Napier, U of Texas, Austin; Michelle Ollie; Timothy Perper; Sara Pocock; Brian Ruh; Takayuki Tatsumi, Keio U, Tokyo; Toshiya Ueno, Wako U, Tokyo; Theresa Winge, U of Northern Iowa; Mark J. P. Wolf, Concordia U; Wendy Siuyi Wong, York U.Frenchy Lunning is professor of liberal arts at the Minneapolis College of Art and Design.

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The first of its kind in the field, this title examines the use of modern, shock-capturing finite volume numerical methods, in the solution of partial differential equations associated with free-surface flows, which satisfy the shallow-water type assumption (including shallow water flows, dense gases and mixtures of materials as special samples). Starting with a general presentation of the governing equations for free-surface shallow flows and a discussion of their physical applicability, the book goes on to analyse the mathematical properties of the equations, in preparation for the presentation of the exact solution of the Riemann problem for wet and dry beds. After a general introduction to the finite volume approach, several chapters are then devoted to describing a variety of modern shock-capturing finite volume numerical methods, including Godunov methods of the upwind and centred type. Approximate Riemann solvers following various approaches are studied in detail as is their use in the Godunov approach for constructing low and high-order upwind TVD methods. Centred TVD schemes are also presented. Two chapters are then devoted to practical applications. The book finishes with an overview of potential practical applications of the methods studied, along with appropriate reference to sources of further information. Features include: * Algorithmic and practical presentation of the methods * Practical applications such as dam-break modelling and the study of bore reflection patterns in two space dimensions * Sample computer programs and accompanying numerical software (details available at www.numeritek.com) The book is suitable for teaching postgraduate students of civil, mechanical, hydraulic and environmental engineering, meteorology, oceanography, fluid mechanics and applied mathematics. Selected portions of the material may also be useful in teaching final year undergraduate students in the above disciplines. The contents will also be of interest to research scientists and engineers in academia and research and consultancy laboratories.

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Explore a rigorous but accessible guide to contemporary approaches to the study of religion from leading voices in the field The Wiley Blackwell Companion to the Study of Religion delivers an expert and insightful analysis of modern perspectives on the study of religion across the humanities and the social sciences. Presupposing no knowledge of the approaches examined in the collection, the book is ideal for undergraduate students who have yet to undertake extensive study in the humanities or social sciences. The book includes perspectives from those in fields as diverse as globalization, cognitive science, the study of emotion, law, esotericism, sex and gender, functionalism, terror, the comparative method, modernism, and postmodernism. Many of the topics covered in the book clearly hail from religious studies, while others are grounded in other areas of academia. All of the chapters contained within are written by recognized authors who show how their chosen discipline contributes to the understanding of the phenomenon of religion. This book also includes topics like: A comprehensive exploration of multiple approaches to religious study, including anthropology, economics, literature, phenomenology, philosophy, psychology, sociology, and theology A review of various topics germane to the study of religion, including the study of the body, cognitive science, the comparative method, death and the afterlife, law, magic, music, and myth A selection of subjects touching on modern trends in extremism and violence, including chapters on terror and violence, fundamentalism, and nationalism A discussion of the influence of modernism and postmodernism in religion Ideal for undergraduate, graduate, and postgraduate students in humanities and social science programs taking courses on religion and myth, The Wiley Blackwell Companion to the Study of Religion will also earn a place in the libraries of specialists working in the fields of Religious Studies, Theology, Sociology, Anthropology, Psychology, Political Science, History, and Philosophy.

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Debate over the nature of science has recently moved from the halls of academia into the public sphere, where it has taken shape as the "science wars." At issue is the question of whether scientific knowledge is objective and universal or socially mediated, whether scientific truths are independent of human values and beliefs. Ronald Giere is a philosopher of science who has been at the forefront of this debate from its inception, and Science without Laws offers a much-needed mediating perspective on an increasingly volatile line of inquiry. Giere does not question the major findings of modern science: for example, that the universe is expanding or that inheritance is carried by DNA molecules with a double helical structure. But like many critics of modern science, he rejects the widespread notion of science--deriving ultimately from the Enlightenment--as a uniquely rational activity leading to the discovery of universal truths underlying all natural phenomena. In these highly readable essays, Giere argues that it is better to understand scientists as merely constructing more or less abstract models of limited aspects of the world. Such an understanding makes possible a resolution of the issues at stake in the science wars. The critics of science are seen to be correct in rejecting the Enlightenment idea of science, and its defenders are seen to be correct in insisting that science does produce genuine knowledge of the natural world. Giere is utterly persuasive in arguing that to criticize the Enlightenment ideal is not to criticize science itself, and that to defend science one need not defend the Enlightenment ideal. Science without Laws thus stakes out a middle ground in these debates by showing us how science can be better conceived in other ways.

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We live under the illusion of progress: as long as GDP is going up and prices stay low, we accept poverty and pollution as unfortunate but inevitable byproducts of a successful economy. In fact, the infallibility of the free market and the necessity of endless growth are so ingrained in the public consciousness that they seem like scientific fact. Jon Erickson asks, why? With the planet in peril and humanity in crisis, how did we get duped into believing the fairytale of economics? And how can we get past the illusion to design an economy that is socially just and ecologically balanced? In The Progress Illusion, Erickson charts the rise of the economic worldview and its infiltration into our daily lives as a theory of everything. Drawing on his own experience as a young economist inoculated in the 1980s era of “greed is good,” Erickson shows how pseudoscience came to dominate economic thought. He pokes holes in the conventional wisdom of neo-classical economics, illustrating how flawed theories about financial decision-making and maximizing efficiency ignore human psychology and morality. Most importantly, he demonstrates how that thinking shaped our politics and determined the course of American public policy. The result has been a system that perpetually concentrates wealth in the hands of a few, while depleting the natural resources on which economies are based. While the history of economics is dismal indeed, Erickson is part of a vigorous reform effort grounded in the realities of life on a finite planet. This new brand of economics is both gaining steam in academia and supporting social activism. The goal is people over profit, community over consumption, and resilience over recklessness. Erickson shows crafting a new economic story is the first step toward turning away from endless growth and towards enduring prosperity.

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This is a novel about the all too common practice in higher academia of hiring part time, non-tenure track faculty to teach students. The faculty hired in these situations often cannot pursue research even though they likely have a Ph.D. This fictional story is mostly set in the 1970s. It follows the tumultuous career of a professor interested in teaching and doing research in biological science. The people who administered the university at the place of his employment expressly do not want faculty to be involved with research. The professor in the story owns a Ph.D., which is a research degree. He holds that being involved in research adds a beneficial dimension to his teaching. Problems arise when he decides to undertake a research problem at his own expense and on his own time. A marine invertebrate zoologist, his search for knowledge centers on the marine organisms that have settled on a lengthy set of pier pilings. When this ultimately leads to publications by himself and with students, his bosses at the university find that seriously troublesome and they try to make him cease. Dire consequences result. The author is a marine biologist and has taught university students for years. So he has extensive experience with this subject area. Of course, what is supposedly found out in the research undertaken in the story is fiction. On the other hand, the marine organisms investigated are real enough species. While the research findings of his main character may be imagined, the approaches to formulating questions and ways to answer them are very much as they might have been in reality. What this author creates here is a telling of the troubles, trials, and tribulations that may come from pursuing new knowledge.

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Practical Pharmaceutics contains essential knowledge on the preparation, quality control, logistics, dispensing and use of medicines. It features chapters written by experienced pharmacists and scientists working in hospitals, academia and industry throughout Europe, including practical examples as well as information on current GMP and GMP-based guidelines and EU-legislation. In this second edition all chapters have been updated with numerous new as well as didactically revised illustrations and tables. A completely new chapter about therapeutic proteins and Advanced Therapy Medicinal Products was added. From prescription to production, from usage instructions to procurement and the impact of medicines on the environment, the book provides step-by-step coverage that will help a wide range of readers, students as well as professionals. It offers product knowledge for all pharmacists working directly with patients and it will enable them to make the required medicine available, to store medicines properly, to adapt medicines if necessary and to dispense medicines with the appropriate information for patients as well as caregivers about product care and how to maintain the quality of the product. The basic knowledge presented in the book will also be valuable for industrial pharmacists to remind and focus them on the application of the medicines manufactured. The basic and practical knowledge on the design, preparation and quality management of medicines can directly be applied by the pharmacists whose main duty is production in community and hospital pharmacies and in industry. Undergraduate as well as graduate pharmacy students will find knowledge presented in a coherent way and fully supported with relevant examples. Practical Pharmaceutics has become a reliable and recognised source for the acquisition of pharmaceutical-technological knowledge. The book is used in the curriculum of a number of international universities and schools of Pharmacy.

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As a software engineer, you’ll encounter countless programming challenges that initially seem confusing, difficult, or even impossible. Don’t despair! Many of these “new” problems already have well-established solutions. Advanced Algorithms and Data Structures teaches you powerful approaches to a wide range of tricky coding challenges that you can adapt and apply to your own applications. Providing a balanced blend of classic, advanced, and new algorithms, this practical guide upgrades your programming toolbox with new perspectives and hands-on techniques. about the technology Data structures and algorithms are the foundations for how programs store and process information. Choosing the optimal algorithms ensures that your programs are fast, efficient, and reliable. about the book Algorithms and Data Structures in Action expands on the basic algorithms you already know to give you a better selection of solutions to different programming problems. In it, you’ll discover techniques for improving priority queues, efficient caching, clustering data, and more. Each example is fully illustrated with graphics, language agnostic pseudo-code, and code samples in various languages. When you’re done, you will be able to implement advanced and little-known algorithms to deliver better performance from your code. what's inside Improving on basic data structures Efficient caching Nearest neighbour search, including k-d trees and S-trees Full ‘pseudo-code’ and samples in multiple languages about the readerFor programmers with basic or intermediate skills. Written in a language-agnostic manner, no specific language knowledge is required. about the author Marcello La Rocca is a research scientist and a full-stack engineer focused on optimization algorithms, genetic algorithms, machine learning and quantum computing. He has contributed to large-scale web applications at companies like Twitter and Microsoft, has undertaken applied research in both academia and industry, and authored the Neatsort adaptive sorting algorithm.

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#2 WALL STREET JOURNAL BESTSELLER, PUBLISHERS WEEKLY BESTSELLER, and a USA TODAY BESTSELLER“Andrew Liveris takes us on a masterclass in collaborative, forward-looking leadership." — Richard Branson, Founder, The Virgin GroupIn Leading Through Disruption, Andrew Liveris provides a new leadership paradigm for resilience and agility in a rapidly changing world. This book is a must-read guide for leaders in various sectors who are keen on not only ensuring current success, but protecting the planet’s future for everyone. Liveris, who was recently chosen to lead the Brisbane 2032 Olympic Organizing Committee and is former Chairman and CEO of The Dow Chemical Company, presents a variety of powerful tools that will enable you to tackle any problem quickly and responsively, with an eye to creating a more equitable, sustainable future. In these pages, you will learn how to: Create and use metrics that quantify the positive impact on all members of society. Collaborate with scientists, politicians, regulators, corporate boards, and other stakeholders to create effective policies that work. Broaden your company’s focus to include both long-term sustainability and short-term profitability without sacrificing the former to gain the latter. Strengthen local communities via corporate investment and advocacy for the improvement of amenities and services for all. Hire team members who fully and proactively support strategies to improve the world and its future. Become a sought-after advisor on how to respond quickly and decisively to uncertainties. Andrew Liveris shares essential wisdom from his four decades of global leadership experience in business, government, academia, and civic society. His book is a powerful tool for any aspiring leader. Finalist for the 2023 Best Book Award for General Business and Management & Leadership

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Design and Development of Biological, Chemical, Food and Pharmaceutical Products has been developed from course material from the authors’ course in Chemical and Biochemical Product Design which has been running at the Technical University Denmark for years. The book draws on the authors’ years of experience in academia and industry to provide an accessible introduction to this field, approaching product development as a subject in its own right rather than a sideline of process engineering In this subject area, practical experience is the key to learning and this textbook provides examples and techniques to help the student get the best out of their projects. Design and Development of Biological, Chemical, Food and Pharma Products aims to aid students in developing good working habits for product development. Students are challenged with examples of real problems that they might encounter as engineers. Written in an informal, student-friendly tone, this unique book includes examples of real products and experiences from real companies to bring the subject alive for the student as well as placing emphasis on problem solving and team learning to set a foundation for a future in industry. The book includes an introduction to the subject of Colloid Science, which is important in product development, but neglected in many curricula. Knowledge of engineering calculus and basic physical chemistry as well as basic inorganic and organic chemistry are assumed. An invaluable text for students of product design in chemical engineering, biochemistry, biotechnology, pharmaceutical sciences and product development. Uses many examples and case studies drawn from a range of industries. Approaches product development as a subject in its own right rather than a sideline of process engineering Emphasizes a problem solving and team learning approach. Assumes some knowledge of calculus, basic physical chemistry and basic transport phenomena as well as some inorganic and organic chemistry.

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When a dissertation crosses my desk, I usually want to grab it by its metaphorical lapels and give it a good shake. "You know something!" I would say if it could hear me. "Now tell it to us in language we can understand!" Since its publication in 2005, From Dissertation to Book has helped thousands of young academic authors get their books beyond the thesis committee and into the hands of interested publishers and general readers. Now revised and updated to reflect the evolution of scholarly publishing, this edition includes a new chapter arguing that the future of academic writing is in the hands of young scholars who meet the broader expectations of readers rather than the narrow requirements of academic committees. At the heart of From Dissertation to Book is the idea that revising the dissertation is fundamentally a process of shifting its focus from the concerns of a narrow audience - a committee or advisors - to those of a broader scholarly audience that wants writing to be both informative and engaging. William Germano offers clear guidance on how to do this, with advice on such topics as rethinking the table of contents, taming runaway footnotes, and confronting the limitations of jargon. Germano draws on his years of experience in both academia and publishing to show writers how to turn a dissertation into a book that an audience will actually enjoy, whether reading on a page or a screen. Germano also explores other, often overlooked, options for dissertations, such as journal articles or chapters in an edited work. With clear directions, engaging examples, and an eye for the idiosyncrasies of academic writing, From Dissertation to Book reveals to recent PhDs the secrets of careful and thoughtful revision - a skill that will be truly invaluable as they add "author" to their curriculum vitae.

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Novel Electrochemical Energy Storage Devices Explore the latest developments in electrochemical energy storage device technologyIn Novel Electrochemical Energy Storage Devices, an accomplished team of authors delivers a thorough examination of the latest developments in the electrode and cell configurations of lithium-ion batteries and electrochemical capacitors. Several kinds of newly developed devices are introduced, with information about their theoretical bases, materials, fabrication technologies, design considerations, and implementation presented.You’ll learn about the current challenges facing the industry, future research trends likely to capture the imaginations of researchers and professionals working in industry and academia, and still-available opportunities in this fast-moving area. You’ll discover a wide range of new concepts, materials, and technologies that have been developed over the past few decades to advance the technologies of lithium‑ion batteries, electrochemical capacitors, and intelligent devices. Finally, you’ll find solutions to basic research challenges and the technologies applicable to energy storage industries.Readers will also benefit from the inclusion of: A thorough introduction to energy conversion and storage, and the history and classification of electrochemical energy storage An exploration of materials and fabrication of electrochemical energy storage devices, including categories, EDLCSs, pseudocapacitors, and hybrid capacitors A practical discussion of the theory and characterizations of flexible cells, including their mechanical properties and the limits of conventional architectures A concise treatment of the materials and fabrication technologies involved in the manufacture of flexible cells Perfect for materials scientists, electrochemists, and solid-state chemists, Novel Electrochemical Energy Storage Devices will also earn a place in the libraries of applied physicists, and engineers in power technology and the electrotechnical industry seeking a one-stop reference for portable and smart electrochemical energy storage devices.

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Nanomaterials - substances smaller than 100 nanometers in size - have been added in recent years to an increasing numbers of consumer products used in day-to-day life; in food packaging, medical devices, pharmaceuticals, cosmetics, odor-resistant textiles and household appliances. The extensive application of nanomaterials in a wide range of products for human use poses a potential for toxicity risk to human health and the environment. Such adverse effects of nanomaterials on human health have triggered the development of a new scientific discipline known as “nanotoxicity” – the study of the toxicity of nanomaterials. Nanotoxicity: From in vivo and in vitro Models to Health Risks provides up-to-date state-of-the-art information presented by recognized experts in this emerging new field in toxicology. It discusses the safety evaluation of nanomaterials in foods, drugs, medical devices, cosmetics and other regulated products and its use in risk analysis for potential regulatory use. Topics covered include: biomarkers for nanotoxicity assessment nanotoxicity assessment by gene expression analysis in vivo and in vitro models for nanotoxicity testing mechanisms of nanotoxicity pharmakokinetics of nanomaterials nanotoxicity of foods including food processing, food packaging and food safety nanotoxicity of drugs including drug development and drug delivery nanotoxicity of cosmetics and consumer products health and environmental impact of nanotoxicity safety evaluation of nanomaterials regulatory impact of nanomaterials Nanotoxicity: From in vivo and in vitro Models to Health Risks is a valuable authoritative source of information for readers from a wide range of disciplines such as toxicology, pharmacology, drug toxicity and food and environmental sciences. The book will be useful to the research community in academia, industry, hospitals and government, as well as to government regulators and risk assessors of foods, drugs and environmental and agricultural products.

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Transport economics and policy analysis is a field which has seen major advances in methodology in recent decades. The transport sector has many unique characteristics - non-storability, economies of scale and scope, indivisibilities and the extensive production of positive and negative externalities that need careful consideration in any analysis. The aim of this Handbook is to provide an overview of the essential research methods with illustrations of how they are applied in practice.The book is divided into six sections - transport costs, externalities, transport demand, pricing and investment, deregulation and privatisation, and transport policy impacts. Each section comprises several chapters, divided by mode of transport or other relevant factor.Some of the unique features include: a comprehensive overview of methods used in transport economics and policy analysis from leading researchers in the field up-to-date methodology for analyzing transport costs and demand examples of how to value the full range of externalities of transport, including both costs and benefits guidance on how to assess the impact of privatisation and (de)regulation, with examples from local public transport, rail and air identification of the relevant factors involved in transport pricing, including roads, public transport, ports and airports an analysis of the neglected topic of equity in transport. This illustrative overview of research methods will be essential to researchers, students and practitioners in academia, government and business.Contributors: J. Bates, O. Betancor, B. de Borger, T. Fowkes, J. Holmgren, J. Owen Jansson, G. de Jong, G. Lindberg, H. Link, R. Liu, A. Ljungberg, A.D. May, H. Meersman, S. Morrison, C. Nash, J.-E. Nilsson, J. de Dios Ortuzar, J. Preston, S. Proost, L.I. Rizzi, W. Rothengatter, G. de Rus, S. Shepherd, A. Smith, J. Stanley, J. Stanley, S. Pettersen Strandenes, D. Van de Velde, E. Van de Voorde, R. Vickerman, P. Wheat, M. Wolanski

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The Liberty for which Patriot Patrick Henry was willing to die was more than a rhetorical flourish. The American Patriots and Founders based their ideas about Liberty upon almost 200 years of experience on their own as well as the heritage of English Common Law and even back to the natural order of Thomas Aquinas, not to mention the philosophy of Aristotle and the Biblical Exodus of the Israelites from Egypt. In over 50-years of scholarship Ellis Sandoz has researched, documented and contemplated the governance of man throughout the ages. The erudition brought to bear in this compact tome reflects a depth and breadth of learning that illuminates the subject with dazzling insight. Yet, he always reminds us that principles of Liberty are readily comprehensible to the common man. Sandoz worries that the present day adherence to political correctness limits our response to obviously murderous terroristic movements. He attacks academia for ignoring the spiritual nature of existence and events. He even chastens “social dogoodism” when it is provided instead of, rather than as a reflection of, spiritual nourishment. The book revolves around the motivation and context of the American Founding and drives home its relevance to contemporary living. The Founders fought against tyranny that attempted to control their physical and spiritual lives. Unjust governance was deemed to be without authority. Aristocrats and commoners ultimately must answer to the Final Authority. These concepts are reflected in the Declaration of Independence: “all men are created equal and they are endowed by their Creator with certain unalienable rights — that among these are life, liberty and the pursuit of happiness.” Sandoz is not only a scholar, but a grandfather; his words will engender Liberty for future generations.

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Understanding the risks involved in hiring new faculty is becoming increasingly important. In Managing Risk in High-Stakes Faculty Employment Decisions Julee T. Flood and Terry Leap critically examine the landscape of US institutions of higher learning and the legal and human resource management practices pertinent to college and university faculty members. To help minimize the potential pitfalls in the hiring and promotion processes, Flood and Leap suggest ways that risk management principles can be applied within the unique culture of academia. Claims of workplace harassment and discrimination, violation of free speech and other First Amendment rights, social movements decrying unequal hiring practices, and the growing number of non-tenure track and adjunct faculty, require those involved in hiring and promotion decisions to be more knowledgeable about contract law, best practices in hiring, and risk management, yet many newly appointed administrators are often not sufficiently trained in these matters or in understanding how they might be applied in an academic setting. Human resource departments, hiring committees, department chairs, and academics seeking faculty jobs need resources such as Managing Risk in High-Stakes Faculty Employment Decisions now more than ever. Outlines critical issues affecting U.S. higher education Analyzes the social and psychological biases that can arise during hiring, promotion, and tenure decisions Discusses contract and constitutional law from the perspective of institutions of higher learning Illustrates complex interactions that shape contractual, constitutional, and collegial issues in institutions of higher learning Examines contract rights and controversies for tenured and tenure-track faculty Describes how risk management processes can help to deal with these complicated, but critical, issues Addresses constitutional issues associated with academic freedom and free speech on campus Investigates the nebulous, but important, issue of collegiality Discusses the future for institutions of higher learning in hiring faculty

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Get great grades from a distance New to online academia and need someone to show you around? You're in the right place—and you're not alone! As more of everything goes online—fueled by tech trends as well as unexpected events like the COVID-19 crisis—it's no surprise that many of us are getting our educations there, too. Online Learning For Dummies is here to welcome you to the gigantic (and gigantically exciting!) virtual campus, and help you get settled in by providing an overview of the endless opportunities offered by distance learning, as well as offering practical advice to make sure you have the right equipment, mindset, and study techniques for success. In a step-by-step style, this friendly guide takes you from the process of determining what sort of online program is right for you, through applying and enrolling, to building the skills you'll need to succeed. You'll learn how to navigate the common features of the online learning classroom, explore the digital etiquette that will help you get the most out of your instructors and fellow students, and discover how to effectively and professionally present your work. You'll also find out how to develop good online study habits to help you avoid distraction, and how to set aside undisturbed time in between juggling the demands of work, family, and social life. Evaluate the latest courses and opportunities Make sure you have the correct hardware and software Develop your online study skills via best practices Avoid digital fatigue Regardless of age or experience, we can all do with a few pointers on how to get more from the vast array of educational opportunities offered online. This book has them all: Get reading, get online, and get the most from that education you've been dreaming about.

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A valuable resource for geologists, engineers, and students across multiple disciplines, this is the most comprehensive and in-depth study of the development of the Baltic Shield, its features as a representative of other similar areas around the world, and the implications for practical applications, such as oil and ore production. Like Sorokhtin's most recent book, The Origins of Natural Diamonds, also available from Wiley-Scrivener at www.wiley.com, this is not just the story of the origin and evolution of the Baltic Shield, but a story about the evolution of the Earth's geology in general. Important to geologists, geophysicists, and engineers across multiple disciplines, written by experts on the Earth's geological evolution, this volume represents the state-of-the-art in major Earth geological processes. Of particular importance to mining engineers and petroleum engineers, it is also a practical guide for those who work in the mining or petroleum industry. Before presenting the most in-depth discussion of the Baltic Shield available and its implications for study by geologists and various industries such as the petroleum industry, the authors present a theory for how the Earth, as we know it, came into existence and developed. They base this theory on scientific evidence and mathematical models, using this as a basis for further explanation of the Earth's geological evolution. Valuable as either a learning tool for the student or as a reference or refresher for the veteran scientist or engineer, the authors explain important geological processes, such as the Earth's origin, composition, and structure, the Earth's energy balance, continental drift, tectonic activity, the evolution of the Earth's crust, and others. It is within this geological framework that the authors offer practical guidance for engineers and scientists who work in industry or academia. It is a must-have for any geologist, geophysicist, or engineer working in mining or petroleum engineering.

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Explores and brings together the existent body of knowledge on building performance analysisShortlisted in the CIBSE 2020 Building Performance Awards Building performance is an important yet surprisingly complex concept. This book presents a comprehensive and systematic overview of the subject. It provides a working definition of building performance, and an in-depth discussion of the role building performance plays throughout the building life cycle. The book also explores the perspectives of various stakeholders, the functions of buildings, performance requirements, performance quantification (both predicted and measured), criteria for success, and the challenges of using performance analysis in practice. Building Performance Analysis starts by introducing the subject of building performance: its key terms, definitions, history, and challenges. It then develops a theoretical foundation for the subject, explores the complexity of performance assessment, and the way that performance analysis impacts on actual buildings. In doing so, it attempts to answer the following questions: What is building performance? How can building performance be measured and analyzed? How does the analysis of building performance guide the improvement of buildings? And what can the building domain learn from the way performance is handled in other disciplines? Assembles the current body of knowledge on building performance analysis in one unique resource Offers deep insights into the complexity of using building performance analysis throughout the entire building life cycle, including design, operation and management Contributes an emergent theory of building performance and its analysis Building Performance Analysis will appeal to the building science community, both from industry and academia. It specifically targets advanced students in architectural engineering, building services design, building performance simulation and similar fields who hold an interest in ensuring that buildings meet the needs of their stakeholders.

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Systematically discusses the growth method, material properties, and applications for key semiconductor materials MOVPE is a chemical vapor deposition technique that produces single or polycrystalline thin films. As one of the key epitaxial growth technologies, it produces layers that form the basis of many optoelectronic components including mobile phone components (GaAs), semiconductor lasers and LEDs (III-Vs, nitrides), optical communications (oxides), infrared detectors, photovoltaics (II-IV materials), etc. Featuring contributions by an international group of academics and industrialists, this book looks at the fundamentals of MOVPE and the key areas of equipment/safety, precursor chemicals, and growth monitoring. It covers the most important materials from III-V and II-VI compounds to quantum dots and nanowires, including sulfides and selenides and oxides/ceramics. Sections in every chapter of Metalorganic Vapor Phase Epitaxy (MOVPE): Growth, Materials Properties and Applications cover the growth of the particular materials system, the properties of the resultant material, and its applications. The book offers information on arsenides, phosphides, and antimonides; nitrides; lattice-mismatched growth; CdTe, MCT (mercury cadmium telluride); ZnO and related materials; equipment and safety; and more. It also offers a chapter that looks at the future of the technique. Covers, in order, the growth method, material properties, and applications for each material Includes chapters on the fundamentals of MOVPE and the key areas of equipment/safety, precursor chemicals, and growth monitoring Looks at important materials such as III-V and II-VI compounds, quantum dots, and nanowires Provides topical and wide-ranging coverage from well-known authors in the field Part of the Materials for Electronic and Optoelectronic Applications series Metalorganic Vapor Phase Epitaxy (MOVPE): Growth, Materials Properties and Applications is an excellent book for graduate students, researchers in academia and industry, as well as specialist courses at undergraduate/postgraduate level in the area of epitaxial growth (MOVPE/ MOCVD/ MBE).

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An integrated presentation of the basic science and clinical applications of anticancer agents Aimed at both undergraduate and postgraduate readers, this unique text provides readers with a fully-integrated presentation of all aspects of the science of anticancer drugs, including their chemistry, pharmacology, and clinical applications. After heart disease, cancer is the number one killer worldwide, and the tumor microenvironment is forever changing, creating an ever-greater demand for safer, more effective anticancer agents. In response to that demand, the $100 billion cancer drug market continues to grow, with our increased understanding of cancer leading to new drugs being used clinically almost every year. Anticancer Therapeutics is divided into three sections. Section 1 is an introduction to cancer and therapeutics, and covers the etiology and cellular and molecular basis of cancer. In Section 2, the authors focus on the anticancer agents — their discovery, synthesis, mode of action, mechanisms of resistance, and adverse reactions. Section 3 focuses on specific cancers, explaining how and why the various agents discussed in Section 2 are used, both individually and in combination, to treat different cancers. Integrates aspects of basic science, including chemistry and pharmacology and clinical medicine in relation to cancer therapeutics Written by an author team comprising specialists in medicinal chemistry, pharmacology, and oncology Features full-color images throughout illustrating how drugs bind to cellular targets and exert their pharmacological effect Divided into three sections, covering the etiology and cellular and molecular basis of cancer, anticancer agents, and drug applications for different cancers. Providing the reader with an integrated understanding of all aspects of the science of anticancer agents, this is an ideal textbook for undergraduates studying medicine, nursing, medicinal chemistry, pharmacy, pharmacology and other allied heath / life sciences. It is also a valuable bench reference for pharmacists, medics, and pharmaceutical researchers working in both academia and industry.

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The automotive industry faces many challenges, including increased global competition, the need for higher-performance vehicles, a reduction in costs and tighter environmental and safety requirements. The materials used in automotive engineering play key roles in overcoming these issues: ultimately lighter materials mean lighter vehicles and lower emissions. Composites are being used increasingly in the automotive industry due to their strength, quality and light weight. Advanced Composite Materials for Automotive Applications: Structural Integrity and Crashworthiness provides a comprehensive explanation of how advanced composite materials, including FRPs, reinforced thermoplastics, carbon-based composites and many others, are designed, processed and utilized in vehicles. It includes technical explanations of composite materials in vehicle design and analysis and covers all phases of composite design, modelling, testing and failure analysis. It also sheds light on the performance of existing materials including carbon composites and future developments in automotive material technology which work towards reducing the weight of the vehicle structure. Key features: Chapters written by world-renowned authors and experts in their own fields Includes detailed case studies and examples covering all aspects of composite materials and their application in the automotive industries Unique topic integration between the impact, crash, failure, damage, analysis and modelling of composites Presents the state of the art in composite materials and their application in the automotive industry Integrates theory and practice in the fields of composite materials and automotive engineering Considers energy efficiency and environmental implications Advanced Composite Materials for Automotive Applications: Structural Integrity and Crashworthiness is a comprehensive reference for those working with composite materials in both academia and industry, and is also a useful source of information for those considering using composites in automotive applications in the future.

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As you read this, your computer is in jeopardy of being hacked and your identity being stolen. Read this book to protect yourselves from this threat. The world’s foremost cyber security experts, from Ruby Lee, Ph.D., the Forrest G. Hamrick professor of engineering and Director of the Princeton Architecture Laboratory for Multimedia and Security (PALMS) at Princeton University; to Nick Mankovich, Chief Information Security Officer of Royal Philips Electronics; to FBI Director Robert S. Mueller III; to Special Assistant to the President Howard A. Schmidt, share critical practical knowledge on how the cyberspace ecosystem is structured, how it functions, and what we can do to protect it and ourselves from attack and exploitation. The proliferation of social networking and advancement of information technology provide endless benefits in our living and working environments. However, these benefits also bring horrors in various forms of cyber threats and exploitations. Advances in Cyber Security collects the wisdom of cyber security professionals and practitioners from government, academia, and industry across national and international boundaries to provide ways and means to secure and sustain the cyberspace ecosystem. Readers are given a first-hand look at critical intelligence on cybercrime and security—including details of real-life operations. The vast, useful knowledge and experience shared in this essential new volume enables cyber citizens and cyber professionals alike to conceive novel ideas and construct feasible and practical solutions for defending against all kinds of adversaries and attacks. Among the many important topics covered in this collection are building a secure cyberspace ecosystem; public–private partnership to secure cyberspace; operation and law enforcement to protect our cyber citizens and to safeguard our cyber infrastructure; and strategy and policy issues to secure and sustain our cyber ecosystem.

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An inside look into patterns and potential prevention plans for one of the most hotly sensationalized crimes A special kind of horror is reserved for mothers who kill their children. Cases such as those of Susan Smith, who drowned her two young sons by driving her car into a lake, and Melissa Drexler, who disposed of her newborn baby in a restroom at her prom, become media sensations. Unfortunately, in addition to these high-profile cases, hundreds of mothers kill their children in the United States each year. The question most often asked is, why? What would drive a mother to kill her own child? Those who work with such cases, whether in clinical psychology, social services, law enforcement or academia, often lack basic understandings about the types of circumstances and patterns which might lead to these tragic deaths, and the social constructions of motherhood which may affect women's actions. These mothers oftentimes defy the myths and media exploitation of them as evil, insane, or lacking moral principles, and they are not a homogenous group. In obvious ways, intervention strategies should differ for a teenager who denies her pregnancy and then kills her newborn and a mother who kills her two toddlers out of mental illness or to further a relationship. A typology is needed to help us to understand the different cases that commonly occur and the patterns they follow in order to make possible more effective prevention plans. Mothers Who Kill Their Children draws on extensive research to identify clear patterns among the cases of women who kill their children, shedding light on why some women commit these acts. The characteristics the authors establish will be helpful in creating more meaningful policies, more targeted intervention strategies, and more knowledgeable evaluations of these cases when they arise.

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"This comprehensive book, which provides a succinct-as-possible glossary of the plethora of terms commonly used in communications, is destined to become an indispensable desk-side reference for engineers and others working in the area." - Curtis Siller, Lucent Technologies Are you sometimes overwhelmed by the overabundance of jargon encountered in technical books and articles? Hargrave's Communications Dictionary is a treasure of simplified communications terms, definitions, acronyms, charts, equations, and a wealth of related information amassed over the author's extensive engineering career. From ATM to Zone Paging, this volume includes over ten thousand definitions of key phrases that readers in industry, government, and academia need to understand. Many definitions incorporate basic tools for problem solving not found in other publications-such as drawings, graphs, charts, and references to IEEE standards. Real-world examples associated with voice and data communications are also included, as well as terminology from peripheral disciplines, including optics, computer science, data networks, and the Internet. Hargrave's Communications Dictionary is a fundamental resource for basic to intermediate-level students and practitioners, and is an essential quick reference for more experienced electronic technicians and engineers. This comprehensive dictionary is also an invaluable text for technical schools and universities. About the Author Frank Hargrave has more than 30 years experience in engineering and manufacturing at several major companies, including Multitech, Inc., ITT, and Yale Security, Inc. He is published in a variety of topics, including active filter design, residential telemetry systems, thermal compensation methods in electronic circuits, and telephone line interface methods. Mr. Hargrave currently runs his own consulting business in Charlotte, NC, where he also teaches classes at the Electronic Computer & Programming Institute. He has been issued 12 U.S. patents and has several others disclosed and in process.

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One approach to organic synthesis is retrosynthetic analysis. With this approach a chemist will start with the structure of their target molecule and progressively cut bonds to create simpler molecules. Reversing this process gives a synthetic route to the target molecule from simpler starting materials. This “disconnection” approach to synthesis is now a fundamental part of every organic synthesis course. Organic Synthesis: The Disconnection Approach, 2nd Edition introduces this important technique, to help students to design their own organic syntheses. There are forty chapters: those on the synthesis of given types of molecules alternate with strategy chapters in which the methods just learnt are placed in a wider context. The synthesis chapters cover many ways of making each type of molecule starting with simple aromatic and aliphatic compounds with one functional group and progressing to molecules with many functional groups. The strategy chapters cover questions of selectivity, protection, stereochemistry, and develop more advanced thinking via reagents specifically designed for difficult problems. Examples are drawn from pharmaceuticals, agrochemicals, natural products, pheromones, perfumery and flavouring compounds, dyestuffs, monomers, and intermediates used in more advanced synthetic work. Reasons for wishing to synthesise each compound are given. This second edition has been fully revised and updated with a modern look. Recent examples and techniques are included and illustrated additional material has been added to take the student to the level required by the sequel, “Organic Synthesis: Strategy and Control”. Several chapters contain extensive new material based on courses that the authors give to chemists in the pharmaceutical industry. Organic Synthesis: The Disconnection Approach, 2nd edition provides a full course in retrosynthetic analysis for chemistry and biochemistry students and a refresher for organic chemists working in industry and academia.

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An accessible introduction to performing meta-analysis across various areas of research The practice of meta-analysis allows researchers to obtain findings from various studies and compile them to verify and form one overall conclusion. Statistical Meta-Analysis with Applications presents the necessary statistical methodologies that allow readers to tackle the four main stages of meta-analysis: problem formulation, data collection, data evaluation, and data analysis and interpretation. Combining the authors' expertise on the topic with a wealth of up-to-date information, this book successfully introduces the essential statistical practices for making thorough and accurate discoveries across a wide array of diverse fields, such as business, public health, biostatistics, and environmental studies. Two main types of statistical analysis serve as the foundation of the methods and techniques: combining tests of effect size and combining estimates of effect size. Additional topics covered include: Meta-analysis regression procedures Multiple-endpoint and multiple-treatment studies The Bayesian approach to meta-analysis Publication bias Vote counting procedures Methods for combining individual tests and combining individual estimates Using meta-analysis to analyze binary and ordinal categorical data Numerous worked-out examples in each chapter provide the reader with a step-by-step understanding of the presented methods. All exercises can be computed using the R and SAS software packages, which are both available via the book's related Web site. Extensive references are also included, outlining additional sources for further study. Requiring only a working knowledge of statistics, Statistical Meta-Analysis with Applications is a valuable supplement for courses in biostatistics, business, public health, and social research at the upper-undergraduate and graduate levels. It is also an excellent reference for applied statisticians working in industry, academia, and government.

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Design and Development of Biological, Chemical, Food and Pharmaceutical Products has been developed from course material from the authors’ course in Chemical and Biochemical Product Design which has been running at the Technical University Denmark for years. The book draws on the authors’ years of experience in academia and industry to provide an accessible introduction to this field, approaching product development as a subject in its own right rather than a sideline of process engineering In this subject area, practical experience is the key to learning and this textbook provides examples and techniques to help the student get the best out of their projects. Design and Development of Biological, Chemical, Food and Pharma Products aims to aid students in developing good working habits for product development. Students are challenged with examples of real problems that they might encounter as engineers. Written in an informal, student-friendly tone, this unique book includes examples of real products and experiences from real companies to bring the subject alive for the student as well as placing emphasis on problem solving and team learning to set a foundation for a future in industry. The book includes an introduction to the subject of Colloid Science, which is important in product development, but neglected in many curricula. Knowledge of engineering calculus and basic physical chemistry as well as basic inorganic and organic chemistry are assumed. An invaluable text for students of product design in chemical engineering, biochemistry, biotechnology, pharmaceutical sciences and product development. Uses many examples and case studies drawn from a range of industries. Approaches product development as a subject in its own right rather than a sideline of process engineering Emphasizes a problem solving and team learning approach. Assumes some knowledge of calculus, basic physical chemistry and basic transport phenomena as well as some inorganic and organic chemistry.

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A balanced introduction to the theoretical foundations and real-world applications of mathematical finance The ever-growing use of derivative products makes it essential for financial industry practitioners to have a solid understanding of derivative pricing. To cope with the growing complexity, narrowing margins, and shortening life-cycle of the individual derivative product, an efficient, yet modular, implementation of the pricing algorithms is necessary. Mathematical Finance is the first book to harmonize the theory, modeling, and implementation of today's most prevalent pricing models under one convenient cover. Building a bridge from academia to practice, this self-contained text applies theoretical concepts to real-world examples and introduces state-of-the-art, object-oriented programming techniques that equip the reader with the conceptual and illustrative tools needed to understand and develop successful derivative pricing models. Utilizing almost twenty years of academic and industry experience, the author discusses the mathematical concepts that are the foundation of commonly used derivative pricing models, and insightful Motivation and Interpretation sections for each concept are presented to further illustrate the relationship between theory and practice. In-depth coverage of the common characteristics found amongst successful pricing models are provided in addition to key techniques and tips for the construction of these models. The opportunity to interactively explore the book's principal ideas and methodologies is made possible via a related Web site that features interactive Java experiments and exercises. While a high standard of mathematical precision is retained, Mathematical Finance emphasizes practical motivations, interpretations, and results and is an excellent textbook for students in mathematical finance, computational finance, and derivative pricing courses at the upper undergraduate or beginning graduate level. It also serves as a valuable reference for professionals in the banking, insurance, and asset management industries.

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This book is a collection of essays in honour of Professor Wang Gungwu. Professor Wang is not only a great historian on Chinese history in general and the Chinese overseas in particular, but has much wider influence through remarkable domain crossing, namely spatial crossing characterised by geographical straddling between inside and outside of China, temporal crossing from the ancient past to the contemporary, inter-disciplinary crossing from history to the social sciences, and intellectual crossing from the academia to public activism. He has been a long-lasting source of inspiration for understanding some of the most pressing and complex issues in our times, including the nature of China's rise and its implications for the regional and world order. In a nutshell, this book presents Wang as a highly active educator-scholar who has achieved the highest academic standard as well as far-reaching influence over issues that concern all walks of life.By focusing on the theme of Chineseness and China's modernity, this book adds depth to the analysis of China's rise and its implications for the region and the world. It contains a chapter providing the most comprehensive and updated review of Wang's scholarship thus far. Another chapter demonstrates how Wang, based on his deep understanding of Chinese civilisation and history, articulates a distinct view of the world order that differs from either the thesis of 'Thucydides's trap' or the advocacy of mutual accommodation. Interestingly, this book also includes a chapter that highlights Wang's 'Southeast Asian-ness', suggesting that Wang's scholarship cautions against not only western-centric views towards China, but also Sino-centric views towards Southeast Asia. In short, this edited volume is both a reference book for understanding Wang's scholarship and an extension of his scholarship to the analysis of China's growing international influence and its implications for the world order.

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The Binding meets The Handmaid's Tale - Discovering a book of dark and ancient power, a convent librarian must defend it with her life. Perfect for fans of dark academia and historical feminist fiction.'A wonderfully rich and absorbing tale' Observer'Expertly crafted and beautifully told' Jennifer Saint'All so good. I read it in two days flat, and wish I had spaced it out more' ⭐ ⭐ ⭐ ⭐ ⭐ READER REVIEWBeatrice is the convent's librarian. For years, she has shunned the company of her sisters, finding solace only with her manuscripts. Then, one carnival night, two women, bleeding and stricken, are abandoned outside the convent's walls. Moments from death, one of them presses something into Beatrice's hands: a bewitching book whose pages have a dangerous life of their own.But men of the faith want the book destroyed, and a zealous preacher has tracked it to her door. Her sisters' lives - or her obsession. Beatrice must decide.The book's voice is growing stronger.An ancient power uncoils.Will she dare to listen?More praise for THE BOOK OF EVE:'What an extraordinary book' Harriet Tyce 'A ravishing, erudite feminist hijack of Renaissance Florence' Alice Albinia'A beautifully written, utterly enthralling read' Karen Coles 'Mysterious, bewitching and beautiful' Elizabeth Lee'Brutal and haunting' Melissa Fu 'Erudite and bewitching' Costanza CasatiAnd some early reader reviews:'It is a tribute to female strength, power and resilience' ⭐ ⭐ ⭐ ⭐ ⭐'A very interesting take on myth, mythology and the power of women when they work together for the greater good' ⭐ ⭐ ⭐ ⭐'The writing was excellent with a compelling storyline and well developed characters and a fantastic setting' ⭐ ⭐ ⭐ ⭐ ⭐'An emotional journey, I absolutely loved the story and characters' ⭐ ⭐ ⭐ ⭐

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One approach to organic synthesis is retrosynthetic analysis. With this approach a chemist will start with the structure of their target molecule and progressively cut bonds to create simpler molecules. Reversing this process gives a synthetic route to the target molecule from simpler starting materials. This “disconnection” approach to synthesis is now a fundamental part of every organic synthesis course. Organic Synthesis: The Disconnection Approach, 2nd Edition introduces this important technique, to help students to design their own organic syntheses. There are forty chapters: those on the synthesis of given types of molecules alternate with strategy chapters in which the methods just learnt are placed in a wider context. The synthesis chapters cover many ways of making each type of molecule starting with simple aromatic and aliphatic compounds with one functional group and progressing to molecules with many functional groups. The strategy chapters cover questions of selectivity, protection, stereochemistry, and develop more advanced thinking via reagents specifically designed for difficult problems. Examples are drawn from pharmaceuticals, agrochemicals, natural products, pheromones, perfumery and flavouring compounds, dyestuffs, monomers, and intermediates used in more advanced synthetic work. Reasons for wishing to synthesise each compound are given. This second edition has been fully revised and updated with a modern look. Recent examples and techniques are included and illustrated additional material has been added to take the student to the level required by the sequel, “Organic Synthesis: Strategy and Control”. Several chapters contain extensive new material based on courses that the authors give to chemists in the pharmaceutical industry. Organic Synthesis: The Disconnection Approach, 2nd edition provides a full course in retrosynthetic analysis for chemistry and biochemistry students and a refresher for organic chemists working in industry and academia.

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Asymmetric Hydrogenation and Transfer Hydrogenation Discover the latest developments in homogeneous asymmetric (transfer) hydrogenation with this up-to-date resourceAsymmetric Hydrogenation and Transfer Hydrogenation delivers a current and cutting-edge investigation of homogenous asymmetric hydrogenation and transfer hydrogenation reactions of prochiral substrates by using organometallic catalysts (like ruthenium, rhodium, iridium, iron, and copper) and organic catalysts.Distinguished researchers and editors Virginie Ratovelomanana-Vidal and Phannarath Phansavath also offer readers a comprehensive walkthrough of substituted ketones through dynamic kinetic resolution, as well a presentation of the mechanisms and application of asymmetric hydrogenation reactions to the synthesis of biologically relevant compounds.The book comprehensively details its complex subject matter clearly and plainly and covers everything from catalyst development and reactions to mechanisms and applications in academia and industry. The papers included within come from many of the leading voices in their respective fields and represent the newest and best research available today.Compiled for researchers and private-industry chemists alike, Asymmetric Hydrogenation and Transfer Hydrogenation also discusses a wide variety of other topics like: A discussion of the development of chiral metal catalysts for asymmetric transfer hydrogenation Several examinations of asymmetric transfer hydrogenation of a variety of chemical groups, including ketones, aryl and heteroaryl ketones, substituted ketones, and heteroaromatic compounds, alkenes, and imines An exploration of the mechanism of asymmetric hydrogenation and continuous flow asymmetric hydrogenation A full and thorough treatment of the industrial applications of asymmetric hydrogenation Perfect for catalytic chemists, chemists working on or with organometallics, organic chemists, natural product chemists, pharmaceutical chemists, medicinal chemists, and industrial chemists, Asymmetric Hydrogenation and Transfer Hydrogenation also belongs on the bookshelves of research and university institutes and libraries who wish to expand their selection on a topic fundamental to organic synthesis.

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A comprehensive source of information about modern drying technologies that uniquely focus on the processing of pharmaceuticals and biologicals Drying technologies are an indispensable production step in the pharmaceutical industry and the knowledge of drying technologies and applications is absolutely essential for current drug product development. This book focuses on the application of various drying technologies to the processing of pharmaceuticals and biologicals. It offers a complete overview of innovative as well as standard drying technologies, and addresses the issues of why drying is required and what the critical considerations are for implementing this process operation during drug product development. Drying Technologies for Biotechnology and Pharmaceutical Applications discusses the state-of-the-art of established drying technologies like freeze- and spray- drying and highlights limitations that need to be overcome to achieve the future state of pharmaceutical manufacturing. The book also describes promising next generation drying technologies, which are currently used in fields outside of pharmaceuticals, and how they can be implemented and adapted for future use in the pharmaceutical industry. In addition, it deals with the generation of synergistic effects (e.g. by applying process analytical technology) and provides an outlook toward future developments. -Presents a full technical overview of well established standard drying methods alongside various other drying technologies, possible improvements, limitations, synergies, and future directions -Outlines different drying technologies from an application-oriented point of view and with consideration of real world challenges in the field of drug product development -Edited by renowned experts from the pharmaceutical industry and assembled by leading experts from industry and academia Drying Technologies for Biotechnology and Pharmaceutical Applications is an important book for pharma engineers, process engineers, chemical engineers, and others who work in related industries.

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Since 1954, a discrete and select group of wealthy and powerful individuals have attended a private, yearly conference to discuss matters of their choosing. This group represents European and North American elites, as well as new talent and rising stars, from the worlds of politics, business, media, academia, the military and even royalty, and has included household names such as Margaret Thatcher, Henry Kissinger and even Prince Philip. In recent years their number have featured David Cameron, Tony Blair, Angela Merkel, Bill Clinton and David Rockefeller. These are 'the Bilderbergers', named after the hotel where their secret gatherings were first hosted. What is their purpose, why do they meet, and what do they want? Investigative writer Gerhard Wisnewski explores the numerous claims of conspiracy that swirl around the group, revealing names of participants, their agendas and their goals. The scene opens in the sun-kissed seaside resort of Vouliagmeni, Greece, where Wisnewski attempts to observe and report on a Bilderberg conference. He soon attracts aggressive attention from police and undercover security, and it is made abundantly clear he is not welcome. From this rude introduction, Wisnewski works backwards to the founding of the Bilderbergers in 1954 by a shadowy Jesuit with secret service allegiances. Examining records and hidden reports, Wisnewski uncovers the true history of the organization, the alliances among key individuals and their common interests. Are the Bilderbergers puppet-masters, pulling strings behind the scenes? Are plans afoot to create a global government and a new political system? To what extent do they represent a clandestine super-government? This book offers a unique view into the workings of power, and the secret methods of those who seek to govern and control behind the scenes.

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Winner of the St Ermin's Intelligence Book of the Year Award. 'One of the great biographies of 2015.' The TimesFully updated edition including recently released information. A Guardian Book of the Year. The Times Best Biography of the Year. Mail on Sunday Biography of the Year. Daily Mail Biography of Year. Spectator Book of the Year. BBC History Book of the Year. 'A remarkable and definitive portrait ' Frederick Forsyth'Andrew Lownie's biography of Guy Burgess, Stalin's Englishman ... shrewd, thorough, revelatory.' William Boyd'In the sad and funny Stalin's Englishman, [Lownie] manages to convey the charm as well as the turpitude.' Craig BrownGuy Burgess was the most important, complex and fascinating of 'The Cambridge Spies' - Maclean, Philby, Blunt - all brilliant young men recruited in the 1930s to betray their country to the Soviet Union. An engaging and charming companion to many, an unappealing, utterly ruthless manipulator to others, Burgess rose through academia, the BBC, the Foreign Office, MI5 and MI6, gaining access to thousands of highly sensitive secret documents which he passed to his Russian handlers.In this first full biography, Andrew Lownie shows us how even Burgess's chaotic personal life of drunken philandering did nothing to stop his penetration and betrayal of the British Intelligence Service. Even when he was under suspicion, the fabled charm which had enabled many close personal relationships with influential Establishment figures (including Winston Churchill) prevented his exposure as a spy for many years.Through interviews with more than a hundred people who knew Burgess personally, many of whom have never spoken about him before, and the discovery of hitherto secret files, Stalin's Englishman brilliantly unravels the many lives of Guy Burgess in all their intriguing, chilling, colourful, tragi-comic wonder.

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A mathematically rigorous explanation of how manufacturing deviations and damage on the working surfaces of gear teeth cause transmission-error contributions to vibration excitations Some gear-tooth working-surface manufacturing deviations of significant amplitude cause negligible vibration excitation and noise, yet others of minuscule amplitude are a source of significant vibration excitation and noise. Presently available computer-numerically-controlled dedicated gear metrology equipment can measure such error patterns on a gear in a few hours in sufficient detail to enable accurate computation and diagnosis of the resultant transmission-error vibration excitation. How to efficiently measure such working-surface deviations, compute from these measurements the resultant transmission-error vibration excitation, and diagnose the manufacturing source of the deviations, is the subject of this book. Use of the technology in this book will allow quality spot checks to be made on gears being manufactured in a production run, to avoid undesirable vibration or noise excitation by the manufactured gears. Furthermore, those working in academia and industry needing a full mathematical understanding of the relationships between tooth working-surface deviations and the vibration excitations caused by these deviations will find the book indispensable for applications pertaining to both gear-quality and gear-health monitoring. Key features: Provides a very efficient method for measuring parallel-axis helical or spur gears in sufficient detail to enable accurate computation of transmission-error contributions from working-surface deviations, and algorithms required to carry out these computations, including examples Provides algorithms for computing the working-surface deviations causing any user-identified tone, such as ‘ghost tones,’ or ‘sidebands’ of the tooth-meshing harmonics, enabling diagnosis of their manufacturing causes, including examples Provides explanations of all harmonics observed in gear-caused vibration and noise spectra. Enables generation of three-dimensional displays and detailed numerical descriptions of all measured and computed working-surface deviations, including examples

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Before putting digital systems for information technology or telecommunication applications on the market, an essential requirement is to perform tests in order to comply with the limits of radiated emission imposed by the standards. This book provides an investigation into signal integrity (SI) and electromagnetic interference (EMI) problems. Topics such as reflections, crosstalk, switching noise and radiated emission (RE) in high-speed digital systems are covered, which are essential for IT and telecoms applications. The highly important topic of modelling is covered which can reduce costs by enabling simulation data to demonstrate that a product meets design specifications and regulatory limits. According to the new European EMC directive, this can help to avoid the expensive use of large semi-anechoic chambers or open area test sites for radiated emission assessments. Following a short introduction to signalling and radiated interference in digital systems, the book provides a detailed characterization of logic families in terms of static and dynamic characteristic useful for modelling techniques. Crosstalk in multi-coupled line structures are investigated by analytical, graphical and circuit-based methods, and techniques to mitigate these phenomena are provided. Grounding, filtering and shielding with multilayer PCBs are also examined and design rules given. Written by authors with extensive experience in industry and academia. Explains basic conceptual problems from a theoretical and practical point of view by using numerous measurements and simulations. Presents models for mathematical and SPICE-like circuit simulators. Provides examples of using full-wave codes for SI and RE investigations. Companion website containing lists of codes and sample material. Signal Integrity and Radiated Emission of High-Speed Digital Systems is a valuable resource to industrial designers of information technology, telecommunication equipment and automation equipment as well as to development engineers. It will also be of interest to managers and designers of consumer electronics, and researchers in electronics.

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Graphene for Post-Moore Silicon Optoelectronics Provides timely coverage of an important research area that is highly relevant to advanced detection and control technology Projecting device performance beyond the scaling limits of Moore’s law requires technologies based on novel materials and device architecture. Due to its excellent electronic, thermal, and optical properties, graphene has emerged as a scalable, low-cost material with enormous integration possibilities for numerous optoelectronic applications. Graphene for Post-Moore Silicon Optoelectronics presents an up-to-date overview of the fundamentals, applications, challenges, and opportunities of integrating graphene and other 2D materials with silicon (Si) technologies. With an emphasis on graphene-silicon (Gr/Si) integrated devices in optoelectronics, this valuable resource also addresses emerging applications such as optoelectronic synaptic devices, optical modulators, and infrared image sensors. The book opens with an introduction to graphene for silicon optoelectronics, followed by chapters describing the growth, transfer, and physics of graphene/silicon junctions. Subsequent chapters each focus on a particular Gr/Si application, including high-performance photodetectors, solar energy harvesting devices, and hybrid waveguide devices. The book concludes by offering perspectives on the future challenges and prospects of Gr/Si optoelectronics, including the emergence of wafer-scale systems and neuromorphic optoelectronics. Illustrates the benefits of graphene-based electronics and hybrid device architectures that incorporate existing Si technology Covers all essential aspects of Gr/Si devices, including material synthesis, device fabrication, system integration, and related physics Summarizes current progress and future challenges of wafer-scale 2D-Si integrated optoelectronic devices Explores a wide range of Gr/Si devices, such as synaptic phototransistors, hybrid waveguide modulators, and graphene thermopile image sensors Graphene for Post-Moore Silicon Optoelectronics is essential reading for materials scientists, electronics engineers, and chemists in both academia and industry working with the next generation of Gr/Si devices.

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Highlights the importance and benefit of mass spectrometry-based metabolomics for identifying biomarkers that accurately screen for potential biomarkers of diseases Mass spectrometry-based metabolomics offer new opportunities for biomarker discovery in complex diseases and may provide pathological understanding of diseases beyond traditional technologies. It is the systematic analysis of low-molecular-weight metabolites in biological samples and has been applied to discovering and identifying the perturbed pathways. Currently, mass spectrometry-based metabolomics has become an important tool in clinical research and the diagnosis of human disease. Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines comprehensively presents the current state, challenges, and applications of high-throughput mass spectrometry-based metabolomics such as metabolites analysis, biomarker discovery, technical challenges, discovery of natural product, mechanism interpretation of action, discovery of active ingredients, clinical application and precision medicine, and enhancing their biomedical value in a real world of biomedicine, shedding light on the potential for spectrometry-based metabolomics. It highlights the value of mass spectrometry-based metabolomics and metabolism to address the complexity of herbal medicines in systems pharmacology, especially, to link phytochemical analysis with the assessment of pharmacological effect and therapeutic potential. Each chapter has been laid out with introduction, method, up-to-date literature, identification of biomarker, and applications Covers the current state, challenges, and applications of high-throughput mass spectrometry-based metabolomics in the discovery of biomarker, active ingredients, natural product, etc. Constitutes a unique and indispensable practical guide for any phytochemistry or related laboratory, and provides hands-on description of new techniques Provides a guide for new practitioners of pharmacologists, pharmacological scholars, drug developers, botanist, researchers of traditional medicines. Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines provides a landmark of mass spectrometry-based metabolomics research and a beneficial guideline to graduate students and researchers in academia, industry, and technology transfer organizations in all biomedical science fields.

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Biodegradable Polymers in the Circular Plastics Economy A comprehensive overview of the burgeoning field of biodegradable plastics As the lasting impact of humanity’s reliance on plastics comes into focus, scholars have begun to seek out solutions to plastic litter. In Biodegradable Polymers in the Circular Plastics Economy, an accomplished team of researchers delivers a focused guide (1) to understand plastic degradation and its role in waste hierarchy besides recycling, and (2) to create and use biodegradable plastics where appropriate. Created preferably from renewable resources, these eco-friendly polymers provide an opportunity to create sustainable and lasting solutions to the growing plastic-driven pollution problem. The broad approach to this handbook allows the authors to cover all aspects of these emerging materials, ranging from the problems present in the current plastics cycle, to the differences in type, production, and chemistry available within these systems, to end-of-life via recycling or degradation, and to life-cycle assessments. It also delves into potential commercial and policy issues to be addressed to successfully deploy this technology. Readers will also find: A thorough introduction to biodegradable polymers, focusing not only on the scientific aspects, but also addressing the larger political, commercial, and consumer concerns Mechanisms of biodegradation and the environmental impact of persistent polymers An in-depth discussion of degradable/hydrolysable polyesters, polysaccharides, lignin-based polymers, and vitrimers Management of plastic waste and life cycle assessment of bio-based plastics Biodegradable Polymers in the Circular Plastics Economy is the perfect overview of this complicated but essential research field and will appeal to polymer chemists, environmental chemists, chemical engineers, and bioengineers in academia and industry. The book is intended as a step towards a circular plastics economy that relies heavily on degradable plastics to sustain it.

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Medical Product Regulatory Affairs Hands-on guide through the jungle of medical regulatory affairs for every professional involved in bringing new products to market Based on a module prepared by the authors for an MSc course offered by the University of Limerick, Ireland, Medical Product Regulatory Affairs is a comprehensive and practical guide on how pharmaceutical and medical devices are regulated within the major global markets. The Second Edition builds on the success of the first with an even wider scope and full coverage of new EU regulations on the safe use of medical devices. Following a look at drug development, complete sections are devoted to national and EU regulatory issues, manufacturing license application and retention, and regulation in the USA. Other topics dealt with include CDER, CBER and marketing and manufacturing licenses, the ICH process and Good Laboratory/Clinical/ Manufacturing Practices. Medical Product Regulatory Affairs includes information on: Aims and structure of regulation, covering purpose and principles of regulation, national and EU legislative processes, and pharmacopeia Regulatory strategy, covering product development and manufacturing, market vigilance, quality assurance systems, personnel, and documentation Drug discovery and development, covering prescription status, physical properties, therapeutic use, and drug discovery, development, and delivery Non-clinical studies, covering non-clinical study objectives and timing, pharmacological and pharmacodynamic studies, and bioavailability and bioequivalence Clinical trials, covering trial protocol, monitoring of trials, trial master files, and FDA communications The wide coverage of different product types and the main global markets makes Medical Product Regulatory Affairs ideal for training courses on regulatory affairs in academia and industry. It is also a valuable reference for pharmacologists, bioengineers, pharma engineers, and students in pharmacy to familiarize themselves with the topic.

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In 2008 the level of poets of colour published by major presses was less than 1%. By 2020 it was over 20%. The Complete Works Poetry – an initiative spearheaded by Booker Prize winner Bernardine Evaristo – played a significant role in this change. Supporting 30 poets from 2008 through to 2020, The Complete Works produced an unprecedented number of prizewinners, including the Forward Prizes (3), T.S. Eliot Prize (2), Ted Hughes Award (2), Somerset Maugham Award, Dylan Thomas Prize, Rathbones Folio Prize and Sunday Times Young Writer of the Year Award. TCW Fellows have also gone on to judge every major poetry award, and to take on significant roles in academia and translation, publishing over 40 collections. The Complete Works has become the most successful collective ever formed in British poetry. Mapping the Future offers new work by all 30 writers the programme has supported, including Warsan Shire, Raymond Antrobus, Mona Arshi, Roger Robinson, Inua Ellams, Malika Booker, Sarah Howe, Will Harris, Kayo Chingonyi, Jay Bernard, Yomi Sode and Karen McCarthy Woolf. It also includes highly personal and politically engaged essays re-drawing the map of British poetry by 10 of the 30 poets, touching on some of the most significant topics of our time. Mapping the Future is not just a magnificent anthology of some of the best UK poets, it is also an exploration on how poetry in Britain has become much more inclusive over the past 15 years: what has been won, and what is still being fought for. This anthology offers a timely insight into British poetry and how the voice of the ‘other’ continues to take centre-stage in pivotal times. Mapping the Future is edited by poet Karen McCarthy Woolf, editor of the second two Ten anthologies in The Complete Works series, with Dr Nathalie Teitler, director of The Complete Works.

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Use the most sophisticated sports nutrition information to help you reach your athletic performance goals. In Advanced Sports Nutrition, Third Edition, world-renowned sports nutritionist Dr. Dan Benardot combines the latest research, strategies, and sports nutrition information with his experience in academia and work with elite athletes to help you learn the following: The implications of relative energy deficiency in sport (RED-S) and within-day energy balance so you can maintain crucial energy balance throughout training and competition Optimal ratios and quantities of nutrients, vitamins, and minerals for achieving maximum power, strength, and performance How to avoid gastrointestinal distress during activity The most popular supplements and their effects on your athletic performance Strategies for balancing fluid and electrolytes to avoid dehydration and hyperhydration How to combat the effects of travel, such as jet lag, new foods, sleep disruption, and high altitude Weight-loss and body-composition issues so you can apply appropriate strategies to achieve the optimal strength-to-weight ratio for your sport Sport-specific guidelines for power sports, endurance sports, and those that require both power and endurance To further assist you in distilling the science into practice, you’ll find 13 practical nutrition guides in the appendix. Curious about pregame nutrition, hydration, high-carb snacks, or macronutrient intake? These quick reference sheets help you easily apply the principles to your own nutrition plan. With Advanced Sports Nutrition, Third Edition, you get practical advice for how best to put nutrition science to work for you.Earn continuing education credits/units! A continuing education exam that uses this book is also available. It may be purchased separately or as part of a package that includes both the book and exam.

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The last decade has witnessed the rise of big data in game development as the increasing proliferation of Internet-enabled gaming devices has made it easier than ever before to collect large amounts of player-related data. At the same time, the emergence of new business models and the diversification of the player base have exposed a broader potential audience, which attaches great importance to being able to tailor game experiences to a wide range of preferences and skill levels. This, in turn, has led to a growing interest in data mining techniques, as they offer new opportunities for deriving actionable insights to inform game design, to ensure customer satisfaction, to maximize revenues, and to drive technical innovation. By now, data mining and analytics have become vital components of game development. The amount of work being done in this area nowadays makes this an ideal time to put together a book on this subject.Data Analytics Applications in Gaming and Entertainment seeks to provide a cross section of current data analytics applications in game production. It is intended as a companion for practitioners, academic researchers, and students seeking knowledge on the latest practices in game data mining. The chapters have been chosen in such a way as to cover a wide range of topics and to provide readers with a glimpse at the variety of applications of data mining in gaming. A total of 25 authors from industry and academia have contributed 12 chapters covering topics such as player profiling, approaches for analyzing player communities and their social structures, matchmaking, churn prediction and customer lifetime value estimation, communication of analytical results, and visual approaches to game analytics. This book’s perspectives and concepts will spark heightened interest in game analytics and foment innovative ideas that will advance the exciting field of online gaming and entertainment.

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