Search results for ""Pan Stanford Publishing Pte Ltd""

Bioadhesion is often defined as the state in which two materials, at least one of which is biological in nature, are held together for extended periods of time by interfacial forces. It is an area of active multidisciplinary research, where engineers, scientists—including chemists, physicists, biologists, and medical experts—materials’ producers, and manufacturers combine their knowledge. From the practical point of view, bioadhesive systems have been used for several years for medical applications such as dentistry and orthopedics and are now entering new fields, for example, tissue sealing and directed drug delivery systems. Understanding bioadhesion mechanisms is of prime importance while exploring desired adhesion for bioadhesion applications such as sealants as well as successful prevention of undesired adhesion of biomolecules, cells, or organisms. Controlling the occurrence of bioadhesion events is also an important problem in the design and use of medical devices, biosensors, membranes, ships, and oil rigs. This book provides a comprehensive view of bioadhesion and highlights different aspects of this phenomenon. The first section of the book presents fundamentals aspects of bioadhesion. It also summarizes various direct and indirect methods used to investigate and characterize bioadhesion. The second section describes studies of natural adhesives. These include "wet" adhesives that are produced and secreted by sessile marine organisms such as mussels and sand tubes and "dry" adhesives such as the one characterizing the gecko foot. The third section focuses on biomimetic adhesives. These man-made materials are fabricated on the basis of the lessons learned from nature emphasizing the correlation between nature understanding and biomimetics. Finally, the last section reviews medical applications of adhesive materials, which include surgical sealants, mucoadhesive drug delivery vehicles, and prevention of adhesion on medical devices.

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An important aspect of engineering surfaces is that they need to be multifunctional as designs of machine components require cheaper, lighter, smarter, longer-wearing, and more environmentally friendly surfaces that see applications that are hotter, faster, highly pressurized, and exposed to other increasingly hostile environments. This can be achieved by use of modern advanced materials and coatings, which now usually are coated systems. This is a challenging area as usually there is antagonism between obtaining low friction and low wear as well as between high corrosion resistance and low wear.This book covers the increasingly important aspect for engineering surfaces to be multifunctional with a focus on tribological applications. It captures the state of the art regarding the emerging needs for multifunctional surface design for controlling wear, friction, and corrosion, as well as having decorative, self-healing, and/or self-sensing capabilities. It focuses on coatings and materials that include CVD diamond, diamond-like carbon, and multilayered and functionally graded systems for a range of engineering applications including machine tools, orthopedic joints, aero-engines/gas turbines, automotive engines, glass windows and walls, and offshore and marine sectors. It is a unique book as it discusses a range of wet- and dry-deposited coatings and multifunctional materials not often seen in one publication. It allows the reader to understand a wide range of design concepts and what is possible to achieve by current surface engineering techniques.

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Integrated quantum hybrid devices, built from classical dielectric nanostructures and individual quantum systems, promise to provide a scalable platform to study and exploit the laws of quantum physics. On the one hand, there are novel applications, such as efficient computation, secure communication, and measurements with unreached accuracy. On the other, hybrid devices might serve to explore the limits of our understanding of the physical world, that is, the formalism of quantum mechanics. Thus, optical quantum hybrid systems got into the focus of many researchers worldwide.This book gives a comprehensive yet lucid introduction to the exciting and fast-growing field of integrated quantum hybrid systems. It presents the theoretical and experimental fundamentals and then discusses several recent results and new proposals for future experiments. Illustrated throughout with excellent figures, the book also outlines the way for more complex devices to realize schemes to entangle distant quantum systems on-chip.

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This book introduces recent advances in understanding the crystal structure of carbonate hydroxylapatite (also known as bone mineral), which forms the hard tissue of bones and teeth. Bone mineral is the reservoir for carbon dioxide in the body and maintains the concentration of mineral ions in body fluids at homeostasis. The detailed structure of bone mineral has remained obscure more than 80 years after publication of the basic apatite structure, because of the nanoscale size and poor quality of bone mineral crystals. An entirely new approach to the determination of carbonate apatite structures has resulted in a greatly expanded role for the c-axis channel of bone mineral crystals in the control of metabolic acidosis and blood pH.The book includes chapters on apatite mineralogy and geochemistry, synthesis methods, x-ray structure, infrared spectroscopy, crystal chemistry of carbonate hydroxylapatite, and biological apatites. There are 74 illustrations, 25 tables of data, and 3 appendixes. Discussion of the new research is supported by an outline of the theory behind the methods of investigation and reviews of previous research on hydroxylapatite materials, for the benefit of non-specialist students and researchers.

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This book is a collection of essays by scientists, historians, philosophers of science, and students. The essays meld biotechnology into science fiction stories and thereby open a conversation about the morality of what we may be one day, and what it may mean to be human as our biotechnological endeavors continue to evolve. The biotechnology "revolution," launched on a global scale many decades ago, has taken a direct course toward re-creating life. Yet there are still many choices to be made in shaping the future that it may one day make possible. The book motivates readers toward deep reflection and continual discourse, which are essential if biotechnology is to evolve in ethical, meaningful, and sustainable ways.

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The nonlinear behavior of nitrogen and the passivation effect of hydrogen in dilute nitrides open the way to the manufacture of a new class of nanostructured devices with in-plane variation of the optical band gap. This book addresses the modifications of the electronic structure and of the optical and structural properties induced in these technologically important semiconductors by atomic hydrogen irradiation. The book comprises discussions on experimental results from several techniques, enriched by state-of-the-art theoretical studies aimed at clarifying the origin of hydrogenation effects that lead to the discovery of specific nitrogen–hydrogen complexes. It presents techniques, such as infrared absorption spectroscopy, synchrotron radiation, and nuclear reaction analysis, which have indeed been crucial for addressing the physical origin of hydrogenation effects and their role in fine structural characterization.The book is not a simple assembly of the contributions of different groups on the subject; it rather tells the complete story of the amazing effects of hydrogen irradiation from the first observations to the discovery of their origin and to potential technology transfer. The primary scope of the book is to guide PhD students and new scientists into the field and to inspire similar analysis approaches in other fields.

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The development of molecular electronics has become the mainstream of scientific research in recent decades. Applications include light-emitting diodes, solar cells, thin-film transistors, and sensors, among others. New-generation organic materials possess the virtues of softness, light weight, easy processing, design flexibility, and so on. This book focuses on the preparation of new functional organic materials. It includes a brief theoretical/kinetic discussion. The text lays special emphasis on the design of organic structures and the way they perform the designated functional properties. It will help organic chemists, particularly synthetic chemists, to light up their inspirations.

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A peek into the literature on the environmental health implications of the rapidly developing nanotechnology industry shows that the potential problem of exposure to airborne nanoparticles has not been adequately addressed. The health and safety of nanotechnology workers are of concern because these groups run the greatest risk of exposure to elevated concentrations of nanomaterials. However, a gap exists between the currently available particle measurement methods and those appropriate for the assessment of nanoaerosol exposure.This book presents new ideas and methods to measure the surface area and local deposition of nanoparticles in the lungs and the true value of respirators. It proposes a nanoparticle dosimetric road map that can be used as a general strategy for the assessment of the dose, which is the most important physical cause of adverse effects on health in the case of nanoparticle exposure. The book suggests the use of 1 nm radioactive particles, called unattached activity of radon progeny, as a safe experimental tool for nanoparticle studies, including human studies. It discusses the problems related to the general strategy of risk assessment in nanoparticle exposure and concrete parameters related to dosage. The ideas presented in this book help close the gaps in our knowledge of aerosols in the nanometer range and improve our understanding of nanoparticle behavior in the air and in the human body.

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Scaffolds for tissue engineering are devices that exploit specific and complex physical and biological functions, in vitro or in vivo, and communicate through biochemical and physical signals with cells and, when implanted, with the body environment. Scaffolds are produced mainly with synthetic materials, and their fabrication technologies are derived from already well-established industrial processes, with some new specific technologies having been developed in the last years to address required complexities.Often, a generalist approach is followed for the translation of materials and technologies designed for other applications, without considering the specific role of scaffolds from a physical and biological point of view. The book illustrates scaffold design principles, with particular relevance to the biological requirements needed to control and drive the biological cross talk, and reviews materials and fabrication and validation methods.

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This book is a collection of the major publications of the authors in the emerging area of chemotherapeutic engineering. It describes and demonstrates the concept, feasibility, safety and prospect of chemotherapeutic engineering through a full spectrum of proof-of-concept experiments from design, characterization, in vitro cellular uptake, cytotoxicity, to in vivo pharmacokinetics, biodistribution, and xenograft tumor model of the various nanocarriers, such as prodrugs, micelles, liposomes, and nanoparticles of biodegradable polymers.

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Gynaecologic oncology is one of the most important subjects in gynaecology and a very challenging field. The management of patients with gynaecological cancers is complex, as the impact of the outcome of such cancers can be critical. This handbook covers the basics of carcinogenesis and the advances in the prevention and management of all gynaecologic cancers, including breast cancer. Gynaecologic oncology has always been perceived as the most difficult subject in obstetrics and gynaecology, but this handbook proves it otherwise. The text is presented in a systematic and easy-to-understand manner and is supplemented by plenty of images and illustrations and up-to-date references from established sources. The book also introduces readers to the new FIGO 2009 staging system and will be a very useful reference for researchers and clinicians.

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This handbook on vacuolar and plasma membrane H+-ATPases is the first to focus on an essential link between vacuolar H+-ATPase and the glycolysis metabolic pathway to understand the mechanism of diabetes and the metabolism of cancer cells. It presents recent findings on the structure and function of vacuolar H+-ATPase in glucose promoting assembly and signaling, in addition to describing the regulatory mechanisms of vacuolar H+-ATPase in yeast cells, neural stem cells, kidney cells, cancer cells, as well as under diabetic conditions.

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Zinc oxide (ZnO) in its nanostructured form is emerging as a promising material with great potential for the development of many smart electronic devices. This book presents up-to-date information about various synthesis methods to obtain device-quality ZnO nanostructures. It describes both high-temperature (over 100° C) and low-temperature (under 100° C) approaches to synthesizing ZnO nanostructures; device applications for technical and medical devices, light-emitting diodes, electrochemical sensors, nanogenerators, and photodynamic therapy; and the concept of self-powered devices and systems using ZnO nanostructures. The book emphasizes the utilization of non-conventional substrates such as plastic, paper, and textile as new platforms for developing electronics.

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This book presents the latest developments and applications of micromechanics and nanomechanics. It particularly focuses on some recent applications and impact areas of micromechanics and nanomechanics that have not been discussed in traditional micromechanics and nanomechanics books on metamaterials, micromechanics of ferroelectric/piezoelectric, electromagnetic materials, micromechanics of interface, size effects and strain gradient theories, computational and experimental nanomechanics, multiscale simulations and theories, soft matter composites, and computational homogenization theory. This book covers analytical, experimental, as well as computational and numerical approaches in depth.

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This volume demonstrates show cost analysis can be adapted to MEMS, taking into account the wide range of processes and equipment, the major differences with the established semiconductor industry, and the presence of both large-scale, product-orientated manufacturers and small- and medium-scale foundries. The content examines the processes and equipment sufficiently for the reader to appreciate how costs arise. It examines representative costs are examined in sufficient detail and accuracy for specific equipment, processes, products, or foundries to show how financial models can be introduced to estimate the cost and price for a MEMS product.

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This book highlights the outstanding role of hydrogen in energy processes, where it is the most functional element due to its unique peculiarities that are highlighted and emphasized in the book. The first half of the book covers the great natural hydrogen processes in biology, chemistry, and physics, showing that hydrogen is a trend that can unite all natural sciences. The second half of the book is devoted to the technological hydrogen processes that are under research and development with the aim to create the infrastructure for hydrogen energetics. The book describes the main features of hydrogen that make it inalienable player in processes such as fusion, photosynthesis, and metabolism. It also covers the methods of hydrogen production and storage, highlighting at the same time the exclusive importance of nanotechnologies in those processes.

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The convergence of two powerful technologies—wireless and the Internet—through IPv4/v6 protocol has led to emergence of next-generation networks (NGNs). NGN is no more a network of mere computers but a connected conglomeration of varied networks with diverse physical properties, with a plethora of network elements, along with a variety of real-time multimedia applications. This book covers the entire gamut of technology challenges from physical layer to application layer including security from both academic and industrial perspectives.

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This book provides several examples of how diverse nanofabrication techniques are being used by researchers across the world to fabricate useful materials and devices. A number of research groups present their cutting-edge work on fabricating a variety of nanoscale structures such as split rings, wires, gaps, trenches and holes. The innovative techniques described in this book will be of interest to all who are engaged in research and development of nanofabrication technologies. The book mainly covers application areas in electronics and photonics but the techniques are general enough to be applied to other areas.

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When the size and the shape of materials are reduced to the nanoscale dimension, their physical and chemical properties can change dramatically. This book demonstrates the controlled size and shape of nanostructured materials and their applications. The applications cover photocatalysts, biomedicals, nanomaterials, fuel cells and supercapacitors, lithium-ion batteries, light-emitting diodes, and field emission display. This book may be the first to clearly point out the relationship between the size and the structure of the materials, which strongly affects their properties. Understanding these control parameters has important technological implications for energy conversion and storage, biotechnology, lighting and display, and so forth.

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This book starts with an overview and introduction on the trends in nanofabrication and nanoimprint technology, followed by a detailed discussion on the design, fabrication, and evaluation of nanoimprint biosensors. The proto-model systems and some application examples of this sensor are also included in the chapters. The book will appeal to anyone in the field of nanotechnology, especially nanofabrication, nanophotonics, and nanobiology, or biosensor research.

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This book focuses on the advantages and disadvantages of each of the commonly used quantitative proteomic methods in terms of accuracy, sensitivity, and reproducibility. It also concentrates on the effective applications of these methods that resulted in many discoveries of the role of the proteins expressed in living cells and biological fluids. The book focuses on the description of advantages and disadvantages of each of the commonly used quantitative proteomic methods, and provides concise descriptions of the effective applications of these methods.

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This book provides an in-depth view on engineered nanomaterials (ENM) pulmonary effects and familiarizes readers with unique aspects of nanomaterial application and research, such as the effects of physicochemical properties on cellular uptake and toxicity. It focuses on the diagnostic and therapeutic utilities of nanomaterials in different lung diseases. The book discusses the novel applications of nanotechnology for the treatment of airway diseases such as asthma, allergy, chronic obstructive pulmonary diseases, cystic fibrosis, and lung cancer. It also discusses the strategies to overcome the pathophysiological and technical barriers as an attempt to synchronize the efforts of pulmonary biologists, chemists and clinicians to develop novel nano-based diagnostics, imaging, and therapeutics tools for airway diseases.

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In recent years, the understanding of the pathophysiological processes of atherosclerosis, a chronic inflammatory disease of the vessel wall being the leading cause for mortality in industrial countries, has tremendously increased. The feasibility of translating such knowledge to novel therapeutic approaches is currently being explored at various levels. This book highlights advances in atherosclerosis and links these to relevant therapeutic strategies. It compiles and details cutting-edge research in cardiovascular medicine from internationally renowned authors.

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Robotic surgery has already created a paradigm shift in medical surgical procedures and will continue to expand to all surgical and microsurgical interventions. There is no doubt that in doing so robotic surgical systems, such as the da Vinci surgical system, will become smarter and more sophisticated with the integration, implementation, and synergy of new smart multifunctional material systems that will make surgical tools and equipment more functional in biomimetic sensing and actuation incorporating haptic/tactile feedback to surgeons in connection with kinesthetic interaction with organs during robotic surgery. This book is the first textbook in robotic surgery to discuss the integration of smart multifunctional soft and biomimetic materials with robotic end effectors to provide haptic and tactile feedback to surgeons during robotic surgery. It is also the first textbook in robotic surgery that comes with a solutions manual, which makes it useful as a supplement to faculty members teaching many different programs and courses such as robotics, medical devices, surgical interventions, and many more.This book can be adapted by professors to teach graduate students and researchers, to enable them to further employ their creativity and knowledge, and to undergraduates to enable them to get an excellent grasp of this exciting field. It is also useful for individuals interested in the field for self-study. The background required for this book is college-level mathematics, matrix analysis, geometry, and medical/surgical terminologies.

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The domain of metamaterials now covers many area of physics: electromagnetics, acoustics, mechanics, thermics, or even seismology. Huge literature is now available on the subject but the results are scattered. Although many ideas and possible applications have been proposed, which of these will emerge as a viable technology will only unfold with time.This book covers the fundamental science behind metamaterials, from the physical, mathematical, and numerical points of view, focusing mainly on methods. It concentrates on electromagnetic waves, but would also be useful in studying other types of metamaterials. It presents the structure of Maxwell equations, discusses the homogenization theory in detail, and includes important problems on resonance. It has an entire section devoted to numerical methods (finite elements, Fourier modal methods, scattering theory), which aims to motivate a reader to implement them. The book is not written as a collection of independent chapters but as a textbook with a strong pedagogical flavor.

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This book reports current nanotechnology research from Australia, in addition to being the first trial of a new workshop program for the professional development of early career researchers (ECRs, including research students). It showcases the professional talents and high-quality writing of ECRs and also describes the workshop program, organized under the auspices of the Australian Research Council Nanotechnology Network, designed to facilitate this. The nanotechnology research topics include plasmonics, the building blocks of plasmonic circuits; the use of metal nanoparticles to improve infrared light trapping in solar cell applications; methods for the bulk synthesis of graphene; synthesis of nanorods of vanadium compounds for energy storage; nanodiamonds, superparamagnetic nanoparticles and synthesis of hollow nanostructured silica, along with a discussion of their applications; molecular dynamics modelling of self-cleaning coatings; metal nanostructure-enhanced fluorescence and its biological applications; luminescent nano-bioprobes for bioassays and bioimaging; biomimicry leading to olfactory nano-biosensors; and superparamagnetic nanoparticles as MRI contrast agents.

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This book discusses electrons and photons in and through nanostructures by the first-principles quantum mechanical theories and fundamental concepts (a unified coverage of nanostructured electronic and optical components) behind nanoelectronics and optoelectronics, the material basis, physical phenomena, device physics, as well as designs and applications. The combination of viewpoints presented in the book can help foster further research and cross-disciplinary interaction needed to surmount the barriers facing future generations of technology design.

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This book introduces various fields of metal biotechnology, emphasizing applications for the fields of environment conservation and resource recycling. The topics discussed include wastewater treatment and bioremediation technologies for hazardous metals making use of metal metabolism by microorganisms and other organisms; recovery and recycling of metals from drainage and waste sources; the biological synthesis and processing of new metallic materials and monitoring of metals for industrial uses; and bio-informatics in metal biotechnology. These topics are expected to be of great help for new developments in these new technologies.

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In this book the author describes the discoveries in his laboratory that led to therapy with cultured cells. The first cultured cell type used for therapy was the keratinocyte of the epidermis, for the treatment of burns. Subsequent developments led to the use of cultured cells for the treatment of diseases of the eye, of the joints and of other diseases. Cultured cells for therapy are now being prepared by industries in the US, Japan and Korea and are used in the aforesaid countries, as well as in France, Sweden and Greece, for the treatment of disease.

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Tunneling reactions in chemistry are characterized by the low-temperature limit when the classical contribution is negligible. Many practical applications benefit from the lack of heat and have a deep physical basis. Interesting advantages of chemical synthesis at low temperatures have also been demonstrated. This book covers fundamental and practical aspects of the processes and experimental and theoretical methods used in the field. The chapters are written by leading scientists who have very strong experience in the selected topics, and many practical recommendations can be found in this book.

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This book presents an overview of the current state of research in both synchrotron radiation and structural proteomics from different laboratories worldwide. The book presents recent research results in the most advanced methods of synchrotron radiation analysis, protein micro- and nano crystallography, X-ray scattering and X-ray optics, coherent X-Ray diffraction, and laser cutting and contactless sample manipulation are described in details. The book focuses on biological applications and highlights important aspects such as radiation damage and molecular modeling.

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Biological molecular motors provide most cells with the dynamic systems required for their day-to-day existence. Examples occur in even the simplest organism (e.g. a bacteria virus), and the range of tasks that they carry out is vast. Over the last few years, there has been a large increase in the study of these motors, and it is becoming apparent that many motors will find uses in either bionanotechnology or synthetic biology.Molecular Motors in Bionanotechnology describes a wide range of molecular motors, ranging from chemical motors to biological motors, in a manner that updates, or reviews, both classification of the type of motor and the grouping into families. Many techniques have evolved to study and characterise molecular motors at the single-molecule level (e.g. use of molecular tweezer devices for single-molecule studies). The text introduces the reader to the concepts and benefits of these techniques. In addition, it looks at the structural information and how this helps understand function and, finally, how some of these motors are being used or may be used in the future as part of a synthetic biology approach to building devices and sensors.

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This book examines single-electron circuits as an introduction to the rapidly expanding field of nanoelectronics. It discusses both the analysis and synthesis of circuits with the nanoelectronic metallic single-electron tunneling (SET) junction device. The basic physical phenomena under consideration are the quantum mechanical tunneling of electrons through a small insulating gap between two metal leads, the Coulomb blockade and Coulomb oscillations — the last two resulting from the quantization of charge. The author employs an unconventional approach in explaining the operation and design of single-electron circuits.

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This book offers a fundamental and comprehensive overview of nanomedicine from a systems engineering perspective, making it the first book in the field of quantitative nanomedicine based on systems theory. The book starts by introducing the concept of nanomedicine and provides basic mathematical modeling techniques that can be used to model nanoscale biomedical and biological systems. It then demonstrates how this idea can be used to model and analyze the central dogma of molecular biology, tumor growth and the immune system. Broad applications of the idea are further illustrated by Bayesian networks, multiscale and multiparadigm modeling and AFM engineering.

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In this book, the authors concentrate on the surface Plasmon (SP) waveguide configurations ensuring nanoscale confinement and review the current status of this rapidly emerging field, considering different configurations being developed for nanoscale plasmonic guides and circuits. Both fundamental physics and application aspects of plasmonics are reviewed in detail by the world's leading experts. A unique feature of this book is its strong focus on a particular subfield of plasmonics dealing with subwavelength (nanoscale) waveguiding, an area which is especially important in view of the explosively growing interest in plasmonic interconnects and nanocircuits.

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In recent decades, dendrimers — free-shaped synthetic macromolecules — have garnered a great deal of scientific interest because of their unique molecular nanostructure. Used in a variety of scientific applications, dendrimers are now widely regarded as a safer, more precise and more effective way to practice medicine.This book compiles and details cutting-edge research in science and medicine from the interdisciplinary team of the Michigan Nanotechnology Institute for Medicine and Biological Sciences, which is currently revolutionizing drug delivery techniques through the development of engineered nanodevices. Edited by Istvan J. Majoros and James R. Baker Jr, two prominent nanotechnology researchers, this book will appeal to anyone involved in nanotechnology, macromolecular science, cancer therapy or drug delivery research.

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The field of C-nanoparticles toxicity is, at present, fragmented and contradictory, oscillating between enthusiastic raptures and bitter disappointments. This important book presents an overall, unitary view of the carbon nanoparticle world, in which both the positive and negative aspects of these recently discovered nanomaterials are critically described and elucidated.The book provides an exhaustive account of C-nanotubes toxicity, mechanisms of toxicity and biocompatibility towards human and animal organisms as well as the entire biological environment. The detailed description of the physicochemical properties of these nano-objects will help facilitate discussion on their future applications in the biomedical field.This book is unique in its understanding, interpretation and analysis of the mechanisms related to the physicochemical behavior of C-nanotubes, as its aims is to let readers be in contact with C-nanoparticles in order for them to benefit from the many advantages these nanostructures can offer in the aforesaid field. Contributors include experts in the study of materials biocompatibility and toxicity, mainly because the book concerns carbon-nanoparticles toxicity.

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Heat in most semiconductor materials, including the traditional group IV elements (Si, Ge, diamond), III–V compounds (GaAs, wide-bandgap GaN), and carbon allotropes (graphene, CNTs), as well as emerging new materials like transition metal dichalcogenides (TMDCs), is stored and transported by lattice vibrations (phonons). Phonon generation through interactions with electrons (in nanoelectronics, power, and nonequilibrium devices) and light (optoelectronics) is the central mechanism of heat dissipation in nanoelectronics. This book focuses on the area of thermal effects in nanostructures, including the generation, transport, and conversion of heat at the nanoscale level. Phonon transport, including thermal conductivity in nanostructured materials, as well as numerical simulation methods, such as phonon Monte Carlo, Green’s functions, and first principles methods, feature prominently in the book, which comprises four main themes: (i) phonon generation/heat dissipation, (i) nanoscale phonon transport, (iii) applications/devices (including thermoelectrics), and (iv) emerging materials (graphene/2D). The book also covers recent advances in nanophononics—the study of phonons at the nanoscale. Applications of nanophononics focus on thermoelectric (TE) and tandem TE/photovoltaic energy conversion. The applications are augmented by a chapter on heat dissipation and self-heating in nanoelectronic devices. The book concludes with a chapter on thermal transport in nanoscale graphene ribbons, covering recent advances in phonon transport in 2D materials.The book will be an excellent reference for researchers and graduate students of nanoelectronics, device engineering, nanoscale heat transfer, and thermoelectric energy conversion. The book could also be a basis for a graduate special topics course in the field of nanoscale heat and energy.

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The enormous advances in the immunologic aspects of biotherapeutics and nanomedicines in the past two decades has necessitated an authoritative and comprehensive reference source that can be relied upon by immunologists, biomedical researchers, clinicians, pharmaceutical companies, regulators, venture capitalists, and policy makers alike. This text provides a thorough understanding of immunology, therapeutic potential, clinical applications, adverse reactions, and approaches to overcoming immunotoxicity of biotherapeutics and nanomedicines. It also tackles critical, yet often overlooked topics such as immune aspects of nano-bio interactions, current FDA regulatory guidances, complement activation-related pseudoallergy (CARPA), advances in nanovaccines, and immunogenicity testing of protein therapeutics.

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Additive manufacturing has matured from rapid prototyping through the now popular and "maker"-oriented 3D printing, recently commercialized and marketed. The terms describing this technology have changed over time, from "rapid prototyping" to "rapid manufacturing" to "additive manufacturing," which reflects largely a focus on technology.This book discusses the uptake, use, and impact of the additive manufacturing and digital fabrication technology. It augments technical and business-oriented trends with those in product design and design studies. It includes a mix of disciplinary and transdisciplinary trends and is rich in case and design material. The chapters cover a range of design-centered views on additive manufacturing that are rarely addressed in the main conferences and publications, which are still mostly, and importantly, concerned with tools, technologies, and technical development. The chapters also reflect dialogues about transdisciplinarity and the inclusion of domains such as business and aesthetics, narrative, and technology critique. This is a great textbook for graduate students of design, engineering, computer science, marketing, and technology and also for those who are not students but are curious about and interested in what 3D printing really can be used for in the near future.

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One dimensional electronic materials are expected to be key components owing to their potential applications in nanoscale electronics, optics, energy storage, and biology. Besides, compound semiconductors have been greatly developed as epitaxial growth crystal materials. Molecular beam and metalorganic vapor phase epitaxy approaches are representative techniques achieving 0D–2D quantum well, wire, and dot semiconductor III-V heterostructures with precise structural accuracy with atomic resolution. Based on the background of those epitaxial techniques, high-quality, single-crystalline III-V heterostructures have been achieved. III-V Nanowires have been proposed for the next generation of nanoscale optical and electrical devices such as nanowire light emitting diodes, lasers, photovoltaics, and transistors. Key issues for the realization of those devices involve the superior mobility and optical properties of III-V materials (i.e., nitride-, phosphide-, and arsenide-related heterostructure systems). Further, the developed epitaxial growth technique enables electronic carrier control through the formation of quantum structures and precise doping, which can be introduced into the nanowire system. The growth can extend the functions of the material systems through the introduction of elements with large miscibility gap, or, alternatively, by the formation of hybrid heterostructures between semiconductors and another material systems. This book reviews recent progresses of such novel III-V semiconductor nanowires, covering a wide range of aspects from the epitaxial growth to the device applications. Prospects of such advanced 1D structures for nanoscience and nanotechnology are also discussed.

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Nanoscale metallic and ceramic materials, also called nanomaterials, have held enormous attraction for researchers over the past few years. They demonstrate novel properties compared with conventional (microcrystalline) materials owing to their nanoscale features. Recently, mechanical alloying and powder metallurgy processes for the fabrication of metal–ceramic/alloy–ceramic nanocomposites with a unique microstructure have been developed. This book focuses on the fabrication of nanostructured hydrogen storage materials and their nanocomposites. The potential application of the research presented in the book fits well into the EU Framework Programme for Research and Innovation Horizon 2020, where one of the societal challenges is secure, clean, and efficient energy. Wherever possible, the authors have illustrated the subject by their own results. The goal of the book is to provide comprehensive knowledge about materials for energy applications to graduate students and researchers in chemistry, chemical engineering, and materials science.

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This might be the first book that deals mostly with the 3D technology computer-aided design (TCAD) simulations of major state-of-the-art stress- and strain-engineered advanced semiconductor devices: MOSFETs, BJTs, HBTs, nonclassical MOS devices, finFETs, silicon-germanium hetero-FETs, solar cells, power devices, and memory devices. The book focuses on how to set up 3D TCAD simulation tools, from mask layout to process and device simulation, including design for manufacturing (DFM), and from device modeling to SPICE parameter extraction. The book also offers an innovative and new approach to teaching the fundamentals of semiconductor process and device design using advanced TCAD simulations of various semiconductor structures. The simulation examples chosen are from the most popular devices in use today and provide useful technology and device physics insights. To extend the role of TCAD in today’s advanced technology era, process compact modeling and DFM issues have been included for design–technology interface generation.Unique in approach, this book provides an integrated view of silicon technology and beyond—with emphasis on TCAD simulations. It is the first book to provide a web-based online laboratory for semiconductor device characterization and SPICE parameter extraction. It describes not only the manufacturing practice associated with the technologies used but also the underlying scientific basis for those technologies. Written from an engineering standpoint, this book provides the process design and simulation background needed to understand new and future technology development, process modeling, and design of nanoscale transistors.The book also advances the understanding and knowledge of modern IC design via TCAD, improves the quality in micro- and nanoelectronics R&D, and supports the training of semiconductor specialists. It is intended as a textbook or reference for graduate students in the field of semiconductor fabrication and as a reference for engineers involved in VLSI technology development who have to solve device and process problems. CAD specialists will also find this book useful since it discusses the organization of the simulation system, in addition to presenting many case studies where the user applies TCAD tools in different situations.

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For centuries, orthopaedic surgeons have been managing the pain, limp, and gait disturbance that develop in association with various traumas and diseases of the hip joint. The hip is a ball-and-socket joint that has a good range of movement, but it is stable and rarely dislocates, even after high-impact trauma, and can withstand repeated motion and a fair amount of wear and tear. However, despite its durability, it is not indestructible. With age and use, the cartilage can wear down or become damaged. Overuse of muscles and tendons of the hip, for example, in athletes, leads to hip pain due to muscle strain or tendonitis. Other factors that can cause pain and lead to progressive arthritic changes include the abnormal anatomy a person is born with, conditions that develop during the growth and development of bones, and trauma as well as wear and tear due to ageing. The diagnosis and management of hip injuries have evolved substantially with advances in hip arthroscopy and diagnostic tools such as MRI and new, minimally invasive techniques.This book provides a detailed account of the hip joint’s anatomy and biomechanics and serves as a practical guide for the diagnosis and treatment of hip diseases and injuries at all ages. The book covers recent trends in orthopaedic surgery of the hip joint, including the latest advances in revision total hip arthroplasty (THA), computer-assisted navigation for THA, resurfacing of the hip joint, neoplastic conditions around the hip, and indications, complications, and outcomes of hip arthroscopy. The chapters are written by experts who have contributed greatly to the understanding of problems of the hip joint. The book will be appreciated by undergraduate and postgraduate students, experienced hip surgeons, medical doctors, and practicing consultants in orthopaedics.

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This book presents the multifaceted aspects of rare earth elements (REEs), focusing on both their potential benefits and adverse health effects. The adverse impacts of REEs on human and environmental health raise a growing concern not only in the scientific community but also among a number of stakeholders, potentially including students, media workers, and decision makers. The recognized and potential benefits arising from REE-related technological applications may envisage their further advantages.A limited number of books have been devoted so far to REEs, and they mainly focus on REE-related chemistry, mineralogy, economy, and developing technologies for these elements. This book presents recent research achievements in REE-associated health effects, which have been mostly confined to journal reports on individual laboratory studies so far. It is an updated and balanced approach to REE research and technology. It provides novel yet established information as stated in the title "At the Crossroads between Toxicity and Safety," with particular emphasis on the hormesis phenomenon.

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Space–time transformations as a design tool for a new class of composite materials (metamaterials) have proved successful recently. The concept is based on the fact that metamaterials can mimic a transformed but empty space. Light rays follow trajectories according to Fermat’s principle in this transformed electromagnetic, acoustic, or elastic space instead of laboratory space. This allows one to manipulate wave behaviors with various exotic characteristics such as (but not limited to) invisibility cloaks. This book is a collection of works by leading international experts in the fields of electromagnetics, plasmonics, elastodynamics, and diffusion waves. The experimental and theoretical contributions will revolutionize ways to control the propagation of sound, light, and other waves in macroscopic and microscopic scales. The potential applications range from underwater camouflaging and electromagnetic invisibility to enhanced biosensors and protection from harmful physical waves (e.g., tsunamis and earthquakes). This is the first book that deals with transformation physics for all kinds of waves in one volume, covering the newest results from emerging topical subjects such as transformational plasmonics and thermodynamics.

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Aptamers, often termed as ‘chemical antibodies,’ are an emerging class of synthetic ligands for efficient target-specific molecular recognition. The objective of this book is to highlight recent advances and potential of aptamers in various disease conditions. . This book focuses on the applications of aptamers in targeted nanotherapy, detection, and in molecular imaging in various disease conditions such as cancer, neurological diseases and infectious diseases.

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