Search results for ""author major"

THE INTERNATIONAL BESTSELLER, NOW A MAJOR FILM STARRING KEIRA KNIGHTLEYIn the bitter winter of 1946, Rachael Morgan arrives with her only remaining son Edmund in the ruins of Hamburg. Here she is reunited with her husband Lewis, a British colonel charged with rebuilding the shattered city. But as they set off for their new home, Rachael is stunned to discover that Lewis has made an extraordinary decision: they will be sharing the grand house with its previous owners, a German widower and his troubled daughter. In this charged atmosphere, enmity and grief give way to passion and betrayal.'Profoundly moving, beautifully written. Ponders issues of decency, guilt and forgiveness' Independent'Terrific. Suspicion, resentment and misunderstanding haunt this city. Richly atmospheric' Sunday Telegraph'An extraordinary read' Daily Mail

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THE NEW YORK TIMES BESTSELLER, SOON TO BE A MAJOR TV SERIES It's not what you've lost . . . it's what you've found.One summer morning, a flight takes off from New York to Los Angeles: there are 192 people aboard. When the plane suddenly crashes, twelve-year-old Edward Adler is the sole survivor.In the aftermath, Edward struggles to make sense of his grief, sudden fame and find his place in a world without his family. But then Edward and his neighbour Shay make a startling discovery; hidden in his uncle's garage are letters from the relatives of other passengers - all addressed him.Following the passengers' final hours and Edward's unique coming-of-age, Dear Edward asks one of life's most profound questions:What does it mean not just to survive, but to truly live?---------------------------------'Ann Napolitano's writing is astonishing. I'm in awe' Marian Keyes'A very moving and emotional read' Anne Tyler'Gripping and elegiac, this is a captivating novel about loss, love and growing up' Rosamund Lupton'That rare book that breaks your heart and stitches it back together . . . Don't miss this one' Jodi Picoult

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Part I. Molecular Biology-based Treatment for Depression.- Chapter 1.  Neuroendocrinological Treatment Targets for Depressive Disorder.- Chapter 2. Psychophamacological Approaches for Neural Plasticity and Neurogenesis in Major Depressive Disorder.- Chapter 3. Efficacy, Safety and Tolerability of Psychedelics in Treatment Resistant Depression (TRD).- Chapter 4. Probiotics and Fecal Microbiota Transplantation in Major Depression: Doxa or Episteme?.- Chapter 5. Induced Pluripotent Stem Cells (iPSC) Technology for Major Depression.- Chapter 6. Combining Complementary and Alternative Medicine (CAM) with Conventional Treatments for Major Depressive Disorder.- Part II. Brain Network-based Treatments for Depression.- Chapter 7.  Application of Transcranial Direct and Alternating Current Stimulation (tDCS & tACS) on Major Depressive Disorder.- Chapter 8.  Repetitive Transcranial Magnetic Stimulation (rTMS) in Major Depression.- Chapter 9. Dee

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John Howard's name will forever be linked to the highly successful Pegasus Bridge assault by his glider-born company of the Oxfordshire and Buckinghamshire Light Infantry. His men regarded him with awe and his courage and toughness were bye-words. However this book reveals the human side of the man as well as providing a graphic account of the preparation, actual operation and aftermath of this iconic raid.The Pegasus Diaries is a book that will be enjoyed by men and women alike, presenting as it does a complex man often torn between his high sense of loyalty to his men and devotion to duty.

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In seventeenth-century France, Louis XIV rules with flamboyant ambition. In his domain, wealth and beauty are all; frivolity begets cruelty; science and alchemy collide. From the Hall of Mirrors to the vermin-infested attics of the Chateau at Versailles, courtiers compete to please the king, sacrificing fortune, principles, and even sacred family bonds.'A wonderful book! Adventure, love, history, magic - it's an engrossing story with magnificent characters, balanced perfectly on the edge between,' said DIANA GABALDONBy the fiftieth year of his reign, Louis XIV has made France the most powerful state in the western world, but the Sun King's appetite for glory knows no bounds. In a bold stroke, he sends his natural philosopher on an expedition to seek the source of immortality: the mythical sea monster. For the glory of his God, his country, and his king, Father Yves de la Croix returns with his treasures: one heavy shroud packed in ice . . . and in a covered basin, an imprisoned sea-creature.Marie-Josephe de la Croix has been looking forward to assisting her brother Yves in the scientific study of the sea monster, until she makes a discovery that will threaten everything her brother, the court and the King believe.'The finest alternate history ever, light-hearted and wise - a luminous, radiant novel,' said URSULA K. LE GUINBut in the decadent court of King Louis, where morality is skewed and corruption reigns, will anyone listen to a single voice? Somehow, she must find the courage to follow her heart and her convictions - even at the cost of changing her life forever.

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The first major Hawthorne biography to be published in two decades, featuring original scholarship on both unpublished and published sources The Life of the Author: Nathaniel Hawthorne presents a rich and nuanced portrait of one of America’s greatest writers, exploring the thoughts and ideas of a man whose profound insights about the human condition continue to resonate in the modern day. Accessible to those with little knowledge of Hawthorne, this unique volume uses a new biographical approach based on exhaustive primary research that provides readers with a better understanding of the artist and his work. Author Dale Salwak challenges the presumption that Hawthorne was a reclusive, eccentric, and alienated man whose relevance to modern times is diminishing. Drawing from his forty-five years' experience reading, studying, and teaching Hawthorne, the author reveals a more approachable Hawthorne. In-depth and reflective chapters explore topics such as the circumstances that led Hawthorne to become a writer, the influence of Sophia Hawthorne on her husband’s work, the theory of the unfulfilled homoerotic relationship between Hawthorne and Herman Melville, and more. Offers a fresh reading of Hawthorne’s life and work from birth to death Provides new perspectives on Hawthorne and stories surrounding his work Draws from a wide variety of sources, including novels, tales, children’s books, notebooks, and personal letters to and from Hawthorne Suggests new strategies for teaching Hawthorne to today’s students Includes a detailed index and comprehensive introductory and concluding chapters Highlighting Hawthorne's special contributions to American literature, The Life of the Author: Nathaniel Hawthorne is essential reading for scholars, lecturers, and college students taking courses including Literary History, American Literature, and History of the Novel as well as anyone interested in biography, literature, and creativity. "Dale Salwak has assimilated vast amounts of scholarship on Hawthorne and his circle, and he's crafted a highly readable and brilliant biography. The lines in Hawthorne's astonishing life have never been more clearly drawn. A wonderful book, highly recommend."—Jay Parini, author of Robert Frost: A Life and Borges and Me

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Author of such feats of storytelling as The Woman in White and The Moonstone, Wilkie Collins has traditionally been recognized far more than for his accomplishments as a serious novelist. In this study of The Moonstone, Peter Thoms argues for a new appreciation of this early master of detection and intrigue. Plotting in Collins, Thoms contends, represents much more than the skillful carpentry of the novelist: It constitutes the essential drama of the major novels themselves, as protagonists struggle for control of the stories in which they find themselves embedded. \u201cMr. Thoms’ scholarly contribution is in recognizing an important constructive quality in Collins’ evident fascination with intricate and intriguing plotting. Other critics, he says, have tended to single out Collins’ plots as indications of his superficiality as a writer. Mr. Thoms’ study does, in fact, demonstrate that there is much more to Collins’ elaborate plots than the delights of suspense and detection. So his main claim is justified in that he increases our respect for the ramifications of Collins’ story-telling techniques.\u201d –John R. Reed The Windings of the Labyrinth asserts that the structures of Collins’s major novels possess surprising sophistication – that each of these novels elaborates a quest for identity, and that this quest for a personal story is intimately tied to the emergence of the novel’s structure. In reappraising Collins’s achievement, Thoms has written an accessible study that will be of interest no only to Victorian scholars, readers of Collins, and students of detective fiction but to anyone interested in the relationship between a novel’s plot and its meaning.

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NOW THE TV SERIES 'THE SERPENT QUEEN', STARRING SAMANTHA MORTONThe bestselling revisionist biography of one of the great women of the 16th centuryOrphaned in infancy, Catherine de Medici was the sole legitimate heiress to the Medici family fortune. Married at fourteen to the future Henri II of France, she was constantly humiliated by his influential mistress Diane de Poitiers. When her husband died as a result of a duelling accident in Paris, Catherine was made queen regent during the short reign of her eldest son (married to Mary Queen of Scots and like many of her children he died young). When her second son became king she was the power behind the throne. She nursed dynastic ambitions, but was continually drawn into political and religious intrigues between Catholics and Protestants that plagued France for much of the later part of her life. It had always been said that she was implicated in the notorious Saint Bartholomew's Day Massacre, together with the king and her third son who succeeded to the throne in 1574, but was murdered. Her political influence waned, but she survived long enough to ensure the succession of her son-in-law who had married her daughter Margaret.

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Peter Rabbit 2: The Runaway is in cinemas now! But relive your favourite moments from the first film with this action-packed chapter book!Peter Rabbit is always breaking into Old Mr McGregor's garden and stealing his vegetables. And it's always getting him into trouble! But everything is about to change . . . Will Peter finally be able to take control of the vegetable patch, or will someone stand in his way? Peter Rabbit™ stars James Corden (the voice of Peter Rabbit), Domhnall Gleeson (Mr. McGregor) and Rose Byrne (McGregor's animal loving neighbour, Bea). Bigger and better than ever, this heart-warming tale of adventure will capture the hearts of fans old and new.Other Titles In The Series:Peter Rabbit The Movie: Sticker Activity BookPeter Rabbit 2 NovelisationPeter Rabbit 2 Quiz Book Peter Rabbit 2Sticker Activity BookPeter Rabbit 2 Colouring Sticker Activity BookPerfect for keeping younger Peter Rabbit fans busy for hours!

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Intricate processes involved in perpetuating the multitude of physiological phenomena in the human body often encounter aberrations and omissions in the genetic code of life. While such errors often lead to lethal diseases, at other times they provide distinctive survival advantages and thus unscramble cues to unconventional therapeutic strategies for life-threatening conditions. Hereditary Persistence of Fetal Hemoglobin (HPFH) is one such condition wherein the typically inactivated fetal form of hemoglobin (HbF) remains overexpressed even in adult stages of the bearer's life. Strikingly, this condition is known to ameliorate pathological manifestations in patients with aberrant adult hemoglobin synthesis (e.g. β-hemoglobinopathies like β-thalassemia, sickle cell disease etc.). Early researchers in the field expected such patients to suffer from clinical challenges owing to HbF's high affinity to oxygen and consequent difficulty in its release to cells and tissues. Surprisingly, these patients are known to lead a physiologically normal life. Modern-day hematologists and clinical researchers have looked-up to the concept of "HbF reactivation" as a potential curative strategy for patients suffering from β-hemoglobinopathies like β-thalassemia and sickle cell disease. As a result, several drugs like hydroxyurea, 5-azacytidine, cytosine arabinoside, natural products etc. have been tried in clinics to elevate HbF levels in such patients with limited success and poor understanding on the mechanisms of their action. Associated side-effects and complications of using cytotoxic agents like these restrict their use in most instances. Fortunately, with the advent of newer molecular tools and techniques, researchers are focusing their attention to reengineer the molecular machinery and thus reactivate the gamma-globin gene. This book brings together a selection of chapters dedicated to fetal hemoglobin -- its physiological role, regulation, methodologies to manipulate and future strategies. Researchers and scientists interested in the topic will have a comprehensive understanding of the current concepts on fetal hemoglobin modulation and therefore will serve as a launching pad for their research ideas.

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Renowned evolutionary biologists Peter and Rosemary Grant have produced landmark studies of the Galapagos finches first made famous by Charles Darwin. In How and Why Species Multiply, they offered a complete evolutionary history of Darwin's finches since their origin almost three million years ago. Now, in their richly illustrated new book, 40 Years of Evolution, the authors turn their attention to events taking place on a contemporary scale. By continuously tracking finch populations over a period of four decades, they uncover the causes and consequences of significant events leading to evolutionary changes in species. The authors used a vast and unparalleled range of ecological, behavioral, and genetic data--including song recordings, DNA analyses, and feeding and breeding behavior--to measure changes in finch populations on the small island of Daphne Major in the Galapagos archipelago. They find that natural selection happens repeatedly, that finches hybridize and exchange genes rarely, and that they compete for scarce food in times of drought, with the remarkable result that the finch populations today differ significantly in average beak size and shape from those of forty years ago. The authors' most spectacular discovery is the initiation and establishment of a new lineage that now behaves as a new species, differing from others in size, song, and other characteristics. The authors emphasize the immeasurable value of continuous long-term studies of natural populations and of critical opportunities for detecting and understanding rare but significant events. By following the fates of finches for several generations, 40 Years of Evolution offers unparalleled insights into ecological and evolutionary changes in natural environments.

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Brooklyn's cultural life has always been deeply embedded in its educational and social life, a life that has seen many changes through the 19th and 20th centuries. Although it was one of the largest cities in the US before the Civil War, Brooklyn did not have a permanent performance institution, forcing the residents to look to New York City for culture. This is the first book that investigates the history of Brooklyn's three best-known performing arts institutions: Brooklyn Academy of Music (BAM), Brooklyn Center for the Performing Arts at Brooklyn College (BCBC), and St. Ann's Center for Restoration and the Arts. Divided into three major sections, this work establishes the cultural history and social context in which these three performing arts institutions developed and thrived. Beginning first with an overview of the birth of the city itself, the book features background histories on the founding of BAM, BCBC, and St. Ann's with reference to their programming, management, architecture, design, and construction. It also expands upon the institutions' physical renovations and innovations, and the artistic visions of changing managements throughout the years.

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'One of the great crime novels of all time' Tony Parsons, Express'Nobody has ever quite pulled it off the way Cain does, not Hemingway, and not even Raymond Chandler' Tom Wolfe'It is no accident that movies based on three [of Cain's novels] helped to define the genre known as film noir' NEW YORK REVIEW OF BOOKS'The most starkly elemental thing that has been written for years' EVENING STANDARDThe torrid story of Frank Chambers, the amoral drifter, Cora, the sullen and brooding wife, and Nick Papadakis, the amiable but inconvenient husband, has become a classic of its kind, and established Cain as a major novelist with a spare and vital prose style and a bleak vision of America.

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Geralt of Rivia is on a mission to save his ward, Ciri, and with her the world, in this third novel in the bestselling Witcher series that inspired the Netflix show and video games. The Wizards Guild has been shattered by a coup and, in the uproar, Geralt was seriously injured. The Witcher is supposed to be a guardian of the innocent, a protector of those in need, a defender against powerful and dangerous monsters that prey on men in dark times.But now that dark times have fallen upon the world, Geralt is helpless until he has recovered from his injuries.While war rages across all of the lands, the future of magic is under threat and those sorcerers who survive are determined to protect it. It's an impossible situation in which to find one girl - Ciri, the heiress to the throne of Cintra, has vanished - until a rumour places her in the Niflgaard court, preparing to marry the Emperor. Injured or not, Geralt has a rescue mission on his hands.Translated by David French.

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You're straddling the pitcher’s mound in Shea Stadium. The game rests in your hands. Your heart is pounding. Big money is at stake. You feel thousands of eyes burning your jersey as they wait for a pitch. You gulp at the air trying to settle your nerves. It's go time. Insight Pitch is a sports story that spills over three decades. Retired Major League Baseball pitcher Skip Lockwood tells anecdotes from throughout his career as a ballplayer, starting with his days as a Little Leaguer through his professional tenure with the Kansas City Athletics, Seattle Pilots, Milwaukee Brewers, California Angels, New York Mets, and Boston Red Sox, before his retirement in 1980. Along the way, he details both the on- and off-the-field shenanigans as well as the enormous psychological process that he underwent each and every time he took the mound. Readers will find some laughs along the way and marvel as they share the locker room with legends like Jesse Owens, Satchel Paige, Catfish Hunter, and Yogi Berra. Humorous but insightful, this book makes the perfect addition to any baseball fan's shelf.

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Read the award-winning, critically acclaimed, multi-million-copy-selling science-fiction phenomenon – soon to be a Netflix Original Series from the creators of Game of Thrones. 1967: Ye Wenjie witnesses Red Guards beat her father to death during China's Cultural Revolution. This singular event will shape not only the rest of her life but also the future of mankind. Four decades later, Beijing police ask nanotech engineer Wang Miao to infiltrate a secretive cabal of scientists after a spate of inexplicable suicides. Wang's investigation will lead him to a mysterious online game and immerse him in a virtual world ruled by the intractable and unpredictable interaction of its three suns. This is the Three-Body Problem and it is the key to everything: the key to the scientists' deaths, the key to a conspiracy that spans light-years and the key to the extinction-level threat humanity now faces. Praise for The Three-Body Problem: 'Your next favourite sci-fi novel' Wired 'Immense' Barack Obama 'Unique' George R.R. Martin 'SF in the grand style' Guardian 'Mind-altering and immersive' Daily Mail Winner of the Hugo and Galaxy Awards for Best Novel

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Striving to rescue the international financial system, the US has reverted to debt-driven growth, and its economic benefit is waning while the risk increases. China is veering back to export-led growth and large surpluses. This book analyzes the factors undermining the efforts of nations to pull their economies out of the Great Recession.

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'THE PERFECT HOLIDAY READ' Evening Standard'A JOY FROM START TO FINISH' - Gavin Extence, author of THE UNIVERSE VERSUS ALEX WOODSThere is something about Ove.At first sight, he is almost certainly the grumpiest man you will ever meet. He thinks himself surrounded by idiots - neighbours who can't reverse a trailer properly, joggers, shop assistants who talk in code, and the perpetrators of the vicious coup d'etat that ousted him as Chairman of the Residents' Association. He will persist in making his daily inspection rounds of the local streets.But isn't it rare, these days, to find such old-fashioned clarity of belief and deed? Such unswerving conviction about what the world should be, and a lifelong dedication to making it just so?In the end, you will see, there is something about Ove that is quite irresistible...The word-of-mouth bestseller causing a sensation across Europe, Fredrik Backman's heartwarming debut is a funny, moving, uplifting tale of love and community that will leave you with a spring in your step - and less ready to judge on first impressions a man you might one day wish to have as your dearest friend.

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This annotated translation is the first systematic rendering into any Western language of the nine major treatises on the art of the Japanese No theater by Zeami Motokivo (1363-1443). Zeami, who transformed the No from a country entertainment into a vehicle for profound theatrical and philosophical experience, was a brilliant actor himself, and his treatises touch on every aspect of the theater of his time. His theories, mixing philosophical and practical insights, often seem strikingly contemporary. Since their discovery early in this century. these secret treatises have been considered among the most valuable and representative documents in the history of Japanese aesthetics. They discuss subjects from the art of the playwright to the reciprocal nature of the relationship between performer and audience.

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Available for the first time in paperback, Seven Faces of Philanthropy introduces to you the Seven Faces approach—a powerful tool that enables development professionals to maximize their effectiveness when approaching major donors for gifts. The authors identify and profile seven types of major donors and offer you detailed strategies on how to approach them. Both novice and expert fundraisers will find this framework a valuable supplement to existing strategies and techniques.

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