Search results for ""Taylor Francis Inc""

This is a study of "karayuki-san", impoverished Japanese women sent abroad to work as prostitutes from the 1860s to the 1920s. It follows the life of one prostitute, Osaki, who is persuaded as a child of ten to accept cleaning work in Borneo and then forced to work as a prostitute in a brothel.

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This informative and thoughtful book demonstrates the value of social group work concepts applied to domestic and other forms of violence. Written by social work practitioners, each chapter focuses on a different form of violence and the appropriate models of social work with groups. Using detailed accounts of their own practice and research, professionals explain behavioral, interactional, and humanistic approaches toward varying service service populations--including perpetrators, as well as victims or “survivors.” The samples of creative interventions with victims of childhood sexual abuse, rape, and domestic battering will inspire sympathy and reflection among all professionals who too often see the consequences of victimization in their own practices.

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With compassion and commitment, practicing chaplains draw on a wide range of professional experiences and discuss principles, themes, and guidelines that have enhanced their ministries. These practical and successful approaches are aimed at helping others face the daily professional challenges of health care chaplaincy. The issues and responsibilities of chaplaincy work with a variety of patient populations--AIDS sufferers, long-term care patients, stroke victims, and the terminally ill--are thoroughly explored. Contributors provide creative and innovative methods of meeting the needs of hospital patients and their families as well as health care personnel, such as implementing a volunteer clergy program and establishing a surgical reporting plan.

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In this highly informative book on the sociocultural interactions between alcoholism and drug abuse, experts explore the relationship of such factors as ethnicity, family, religion, and gender to chemical abuse and address important implications for treatment.

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Many books have been written on hazardous waste and nuclear waste separately, but none have combined the two subjects into one single-volume resource. Hazardous and Radioactive Waste Treatment Technologies Handbook covers the technologies, characteristics, and regulation of both hazardous chemical wastes and radioactive wastes. It provides an overview of recent waste technologies.A reference for scientists and engineers, the handbook focuses on waste-related thermal and non-thermal technologies, separation techniques, and stabilization technologies. It includes information on the DOE and DOD waste matrix located at various sites. It reveals current R&D activities in each technology and what improvements can be made in the future. A detailed schematic diagram illustrates each technology so that the process can be explicitly understood. In addition, the handbook covers relative life-cycle cost estimates for treatment systems using various technologies.With contributions from an international panel and extensively peer-reviewed, Hazardous and Radioactive Waste Treatment Technologies Handbook provides the latest information on waste remediation technologies and related regulations. Often in the field you will encounter more than one type of hazardous waste. This handbook gives you the design information you need to decide which technology to use and how to design the equipment for your particular needs. You can then incorporate appropriate technologies into a mixed waste treatment system.

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Today's facility manager is faced with a cross-section of job responsibilities and functions. Facility Management Reference Library CD, Second Edition is a comprehensive 11-volume reference library covering, from a facility manager's perspective, everything from water systems, facility assessment, air quality, lighting, boilers, and pumps to asset protection and terrorism. With more than 3,800 pages of text and graphics, this CD is an economical training, research, and reference resource. This powerful information tool allows you to print, create custom documents, and easily find the information that you need.

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The CRC Handbook of Enthalpy Data of Polymer-Solvent Systems presents data that is as essential to the production, process design, and use of polymers as it is to understanding the physical behavior and intermolecular interactions in polymer solutions and in developing thermodynamic polymer models.Providing an all-encompassing collection of current enthalpy data for all types of polymer solutions, this handbook is a ready companion with Christian Wohlfarth’s previously published handbooks of thermodynamic data for copolymer solutions, aqueous polymer solutions, and polymer solutions at elevated pressures, which contain only a small amount of enthalpic data in comparison to the data presented here. This volume contains 1770 data sets that include enthalpies of mixing and dilution for the entire concentration range as well as partial enthalpies of mixing and solution at infinite dilution. Special appendices allow scientists to access specific systems and data easily. The CRC Handbook of Enthalpy Data of Polymer-Solvent Systems is a practical, one-stop resource that allows polymer chemists, biochemists, chemical engineers, materials scientists, and physical chemists involved in both industrial and laboratory processes to quickly retrieve relevant information as needed.

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Focusing on prevention rather than treatment, Obesity: Dietary and Developmental Influences reviews and evaluates the determinants of obesity. The book uses evidence-based research as a basis to define foods and dietary behaviors that should be supported and encouraged as well as those that should be discouraged. This comprehensive review represents a critical step forward in the quest to identify actionable strategies to prevent obesity.The book describes the potential role of 26 different dietary factors and 8 developmental periods in the prevention of obesity among children and adults. The dietary factors examined include macronutrients, micronutrients, specific types of foods and beverages, snack and meal patterns, portion size, parenting practices, breastfeeding, and more. The factors from each developmental period in the life cycle are examined in the context of the likelihood of obesity development. For each dietary factor and developmental period, four lines of evidence are examined: secular trends, plausible mechanisms, observational studies, and prevention trials. Providing easy access to information, the book features 38 tables that summarize observational studies, 38 graphs depicting trends in dietary intake, and 9 tables that summarize prevention trials. It provides a synopsis of the latest research on obesity, investigating all major lines of evidence, and clarifies common misconceptions while identifying which behaviors to target and which dietary factors show the most promise for prevention.

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Since the first edition that was published in 1998 we have seen manychanges in ophthalmology from advancements in laser surgery to new techniques in cataract surgery. With these new developing advancements symptoms, diagnosis, and treatments in ocular disease have also begun to change. Early diagnosis and management of ocular infection is essential to avoid the risk of blindness. An understanding of the related disease process and drug therapy is a key aid in achieving this. The updated Ocular InfectionSecond Edition covers the basic science of ocular infection, as well as its diagnosis and management of ocular disease, and the changes it is going through.

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With high-quality genome sequences for the important and ubiquitous Aspergilli now available, increased opportunities arise for the further understanding of its gene function, interaction, expression, and evolution. The Aspergilli: Genomics, Medical Aspects, Biotechnology, and Research Methods provides a comprehensive analysis of the research that reveals the main biological attributes of these species. The co-editors are a particularly proficient and prolific pair with long track records of scientific productivity.The book sets the stage with a discussion of basic biology, examining the data on the structure of genomes and comparing the genetic map and annotation methodology. It includes a comparison of metabolic abilities among different Aspergillus spp. and other species, then covers areas such as comparative biology, pathogenic properties, and metabolic capabilities of the Aspergilli. The book reviews established techniques and new methodologies for the post-genomic era in Aspergillus spp. It comes with a CD containing color illustrations to supplement the text. Filling the need for centralized information on a genus that has important economic impacts on agriculture, human health, industry, and pharmacology, the book presents a wide range of data, collected and arranged into one convenient resource. Written by a team of international experts, this is the first in-depth and exhaustive analysis of the genomics of the Aspergilli.

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With the widespread use of GIS, multi-scale representation has become an important issue in the realm of spatial data handling. However, no book to date has systematically tackled the different aspects of this discipline. Emphasizing map generalization, Algorithmic Foundation of Multi-Scale Spatial Representation addresses the mathematical basis of multi-scale representation, specifically, the algorithmic foundation.Using easy-to-understand language, the author focuses on geometric transformations, with each chapter surveying a particular spatial feature. After an introduction to the essential operations required for geometric transformations as well as some mathematical and theoretical background, the book describes algorithms for a class of point features/clusters. It then examines algorithms for individual line features, such as the reduction of data points, smoothing (filtering), and scale-driven generalization, followed by a discussion of algorithms for a class of line features including contours, hydrographic (river) networks, and transportation networks. The author also addresses algorithms for individual area features, a class of area features, and various displacement operations. The final chapter briefly covers algorithms for 3-D surfaces and 3-D features.Providing a thorough treatment of low-level algorithms, Algorithmic Foundation of Multi-Scale Spatial Representation supplies the mathematical groundwork for multi-scale representations of spatial data.

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With the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. Nanoparticulate Drug Delivery Systems addresses the scientific methodologies, formulation, processing, applications, recent trends, and emerging technologies in the research of nanoparticulate drug delivery systems (NPDDS). It extensively covers applications of NPDDS— including lipid nanoparticles for dermal applications; nanocarriers for the treatment of restenosis; and for ocular, central nervous system, and gastrointestinal applications. It also explores its use as an adjuvant for vaccine development.Supplying insight from international experts, this guide Discusses formulation for poorly soluble drugs Presents biological requirements for nanotherapeutic applications Demonstrates the role of nanobiotechnology in the development of nanomedicine Documents recent advances in nanoparticulate technology—including electrospining, formation of microcrystals, and production of liquid crystalline phases Examines the technology of metallic nanoparticles

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A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniques have been used to investigate how cellular and brain circuits may be modified by experience. In each chapter, researchers present findings and explain their innovative methodologies. The book begins by introducing key issues and providing a historical overview of the field of memory consolidation. The following chapters review the putative genetic and molecular mechanisms of cell plasticity, elaborating on how experience could induce gene and protein expression and describing their role in synaptic plasticity underlying memory formation. They explore how putative modifications of brain circuits and synaptic elements through experience can become relatively permanent and hence improve brain function. Interdisciplinary reviews focus on how nerve cell circuitry, molecular expression, neurotransmitter release, and electrical activity are modified during the acquisition and consolidation of long-term memory. The book also covers receptor activation/deactivation by different neurotransmitters that enable the intracellular activation of second messengers during memory formation. It concludes with a summary of current research on the modulation and regulation that different neurotransmitters and stress hormones have on formation and consolidation of memory.

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Because of developments in powerful computer technology, computational techniques, advances in a wide spectrum of diverse technologies, and other advances coupled with cross disciplinary pursuits between technology and its greatly significant applied implications in human body processes, the field of biomechanics is evolving as a broadly significant area. The four volumes of Biomechanical Systems, Techniques, and Applications explore the many areas of significant advances, including dynamics of musculo-skeletal systems; mechanics of hard and soft tissues, muscles, bone remodeling, hard and soft tissue interfaces, blood flow, air flow, flow-prosthesis interfaces, and impact; cardiovascular and respiratory biomechanics; and dynamics of many machine interactions.

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Digital Microfluidic Biochips focuses on the automated design and production of microfluidic-based biochips for large-scale bioassays and safety-critical applications. Bridging areas of electronic design automation with microfluidic biochip research, the authors present a system-level design automation framework that addresses key issues in the design, analysis, and testing of digital microfluidic biochips.The book describes a new generation of microfluidic biochips with more complex designs that offer dynamic reconfigurability, system scalability, system integration, and defect tolerance. Part I describes a unified design methodology that targets design optimization under resource constraints. Part II investigates cost-effective testing techniques for digital microfluidic biochips that include test resource optimization and fault detection while running normal bioassays. Part III focuses on different reconfiguration-based defect tolerance techniques designed to increase the yield and dependability of digital microfluidic biochips. Expanding upon results from ongoing research on CAD for biochips at Duke University, this book presents new design methodologies that address some of the limitations in current full-custom design techniques. Digital Microfluidic Biochips is an essential resource for achieving the integration of microfluidic components in the next generation of system-on-chip and system-in-package designs.

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Molecular and Cell Biology of the Liver features the latest research findings regarding liver structure and function. A unique feature of the book is the brief science reviews that are included in each chapter which provide essential background information to allow readers to better grasp the subject matter within a chapter. The book covers liver biology from the molecular level to groups of liver cells and explains how groups of hepatocytes interact in similar microenvironments. Other important cell types found in the liver are also examined. Illustrations ranging from electron micrographs to fully rendered drawings act as visual aids to help readers understand complex structural-functional interactions. Molecular and Cell Biology of the Liver will benefit hepatologists, gastroenterologists, cell biologists, anatomists, toxicologists, and other researchers interested in liver structure and function.

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With the rapid evolution of multimedia communications, engineers and other professionals are generally forced to hoard a plethora of different texts and journals to maintain a solid grasp on essential ideas and techniques in the field. Wireless Multimedia Communications provides researchers and students with a primary reference to help readers take maximum advantage of current systems and uncover opportunities to propose new and novel protocols, applications, and services. Extract the Essentials of System Design, Analysis, ImplementationA complete technical reference, the text condenses the essential topics of core wireless multimedia communication technologies, convergence, QoS, and security that apply to everything from networking to communications systems, signal processing, and security. From extensive existing literature, the authors distill the central tenets and primary methods of analysis, design, and implementation, to reflect the latest technologies and architectural concepts. The book addresses emerging challenges to inform the system standardization process and help engineers combat the high error rates and stringent delay constraints that remain a significant challenge to various applications and services. Keep Pace with Detailed Techniques to Optimize TechnologyThe authors identify causes of information loss in point-to-point signal transmission through wireless channels, and then they discuss techniques to minimize that loss. They use examples that illustrate the differences in implementing various systems, ranging from cellular voice telephony to wireless Internet access. Each chapter has been carefully organized with the latest information to serve dual purposes as an easy-to-reference guide for professionals and as a principal text for senior-level university students.

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Osteoporosis, a growing epidemic among women in North America, Europe, and Japan, is a painful, costly disease that has presented a treatment challenge to healthcare professionals. Until recently, therapies have focused on agents that slow bone resorption, and have had only limited success at increasing bone mass.However, exciting new developments are on the verge of changing the treatment of this debilitating disorder. Two anabolic agents, the parathyroid hormone (PTH) and the fluoride ion, show tremendous promise as tools for building and retaining bone - with no adverse side effects. Anabolic Treatments for Osteoporosis is a comprehensive account of the latest studies that have been carried out on these two agents, and a thorough assessment of their prospects as osteoporosis therapeutics. This unique book combines basic science and up-to-date clinical data to present a complete picture of this breakthrough in the treatment of a globally significant health issue.

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Micro-nanotechnologies (MNT) are already making a profound impact on our daily lives. New applications are well underway in the US, Asia, and Europe. However, their potentially disruptive nature, along with the public’s concerns, has produced a number of challenges. Commercializing Micro-Nanotechnology Products provides a snapshot of the current market situation and details the need for MNT development. It outlines the problems facing today’s businesses and discusses the processes for commercialization, road mapping, technology transfer analysis, and entrepreneurial development.The book begins by detailing the steps required to turn an idea into a marketable product. The editors give examples of previously successful products and relate to their own experiences in development. Next, the text focuses on the importance of entrepreneurship and the required steps to finance and develop a marketing strategy. It contains various definitions of nanotechnology and how each relates to roadmap and production issues. Three detailed case studies from the leading MNT development and manufacturing companies describe how each venture started and progressed to become a market leader. These studies offer valuable insight into overcoming the challenges related to achieving financial backing and specifying the right product for development. This reference provides the only insightful appraisal of the current status of micro-nanotechnology products. It describes a concise process for product commercialization, from market research to end product realization. Commercializing Micro-Nanotechnologies provides a clear strategy for choosing the right product to development and overcoming challenges in the growing global market.

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The major histocompatibility complex (Mhc) is one of the few identified gene systems in domestic animals that is associated with quantitative traits such as disease resistance, immune response, growth, and reproduction. As knowledge of this important system increases, we move closer toward the reality of genetic enhancement of animal welfare and production efficiency. This book represents the current state of knowledge on the Mhc of agriculturally important animals and explores the latest advances in technology. For the first time, the unique findings of recent Mhc research are presented in a single source.The Major Histocompatibility Complex Region of Domestic Animal Species begins with a discussion of the evolution of Mhc. The chapters are then organized with respect to specific species, with a chapter devoted to each. The Mhc of mice and humans are used as a common reference for comparisons between diverse species. The text concludes with a look at future strategies and directions in Mhc research. Comparative immunologists and geneticists, veterinarians, animal breeders, researchers, and university and postgraduate students will all benefit from this detailed look at the evolution, structure, and organization of Mhc.

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Blinded by emotional rhetoric, political posturing, and genuine fear, previous efforts to defend our way of life against aggressors intent on inflicting personal and economic destruction have proven, in hindsight, to be misguided, panicked, and reactionary. Evaluation and assessment to date is largely focused on reviewing government documents, doing little to alleviate the distorted perspectives from which we vainly attempt to invoke workable policy.In contrast to much of the current literature, Homeland Security Handbook takes a sober, analytical look at the policies, results, and lessons learned in what is still a nascent field. This comprehensive reference considers the myriad factors, implications, and ramifications involved with the practical and effective protection of our safety. Dividing contributions into five sections, this book— Provides an overview and historical perspective of the worldwide threat of terrorism and debates the necessity and danger of highly-centralized government response Explores specific threats to homeland security including the exploitation of our own vulnerabilities. It explores the insidious effect of psycho-terrorism and challenges the economic and military wisdom of launching armies against a nation-less and nebulous threat Offers practical, reasoned advice from practitioners and academic experts on planning, preparedness, prevention, and recoveryReviews supporting case studies from local and foreign governmental response to security and border controlQuantifies the cost of homeland security in terms of funding, as well as the hardships incurred by rash and biased actionsConscious of the multi-faceted nature of the problem, the editor combines theory and practice to address concerns in border and transportation security, emergency preparedness and response, and infrastructure protection.

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Whether you exercise for fun, or in competitive situations, you should understand the important role nutrition plays in fitness. This useful new text focuses on nutrition as it specifically relates to female athletes. It addresses topics of major importance to women in sports, coaches, trainers, sports nutritionists, and physicians. Each chapter is a "mini-course" on a particular aspect of nutrition. Subjects include the nutritional practices of female athletes; the requirements for carbohydrates, proteins, and fats; details on vitamins and minerals, with special emphasis on the nutrients of importance to female athletes; the role of water and electrolytes, including prevention of dehydration and guidelines for optimal fluid replacement; body weight and composition; factors affecting energy balance; how to achieve a healthy competitive weight, and an overview of eating disorders in athletes, including definitions and diagnostic criteria, prevalence, risk factors, and effects on health and performance.

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Processing Foods: Quality Optimization and Process Assessment provides a large body of updated information - helping researchers and industrialists make use of new concepts, technologies and approaches that are at the heart of modern food research. It will be a useful tool in the interweaving of scientific and technological information that the multidisciplinarity of food processing and preservation requires.The book concerns conventional and emerging technologies - reviewing relevant chemical, physical and microbiological changes in food - occurring during processing. It discusses methods to monitor and assess such changes with a view to product optimization. Chapters include reviews of different subjects and specific studies that clarify the issues and their potential applications. The topics are divided into five sections: thermal processing, freezing, drying, high pressure processing and minimal and combined processes.

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This book discusses toxic Microcystis and the toxins from various viewpoints such as classification, cultivation, occurrences in lakes, and relations to zooplankton. The text presents new information on the chemistry, analytical chemistry, toxicology, molecular modeling, and liver tumor promotion of the toxins. Microcystis species are described in relation to morphological features, allozyme genotype, and toxin content. Seasonal changes of Microcystis population are described with special references to toxic species and composition of the toxins. Chemical characteristics of microcystins are reviewed and the process for identification of microcystins is described.

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From the slippery covering on rocks in a stream, to the clogging slime in a bathtub drain, biofilms are present in everyday life in a variety of forms. This seemingly harmless build-up also accounts for 80 percent of all microbial infections. With chapters authored by experienced contributors from academia and industry, Applied Biomedical Microbiology: A Biofilms Approach demonstrates effective ways to combat the health and economic havoc that biofilms are wreaking, while also tapping into their positive potential. Replete with Tables and Illustrations, Many in ColorUnder the editorial guidance of esteemed industrial microbiologist Dr. Daryl Paulson, this book presents an in-depth discussion of medically challenging biofilms. It provides a solid foundation in the basic microbiology of biofilms and then goes on to discuss the biofilms associated with medical devices, catheters, and dental unit water lines as well as those that impact cardiovascular medicine, the gastrointestinal system, periodontal disease, and chronic wounds. This informative work concludes with an exploratory chapter of the various methods used to investigate biofilms. Applied Biomedical Microbiology: A Biofilms Approach presents key information clearly and concisely – a useful guide for environmental, food, and water microbiologists as well as biochemists, pharmaceutical scientists, and product and biofilm engineers.

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One of the first things a student of partial differential equations learns is that it is impossible to solve elliptic equations by spatial marching. This new book describes how to do exactly that, providing a powerful tool for solving problems in fluid dynamics, heat transfer, electrostatics, and other fields characterized by discretized partial differential equations. Elliptic Marching Methods and Domain Decomposition demonstrates how to handle numerical instabilities (i.e., limitations on the size of the problem) that appear when one tries to solve these discretized equations with marching methods. The book also shows how marching methods can be superior to multigrid and pre-conditioned conjugate gradient (PCG) methods, particularly when used in the context of multiprocessor parallel computers. Techniques for using domain decomposition together with marching methods are detailed, clearly illustrating the benefits of these techniques for applications in engineering, applied mathematics, and the physical sciences.

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Culled from the pages of CRC's highly successful, best-selling The Circuits and Filters Handbook, Second Edition, Nonlinear and Distributed Circuits presents a sharply focused, comprehensive review of the fundamental theory behind professional applications of these complex circuits. It supplies a concise, convenient reference to the key concepts, models, and equations necessary to analyze, design, and predict the behavior of nonlinear and distributed circuits, illustrated by frequent examples. Edited by a distinguished authority, this book emphasizes the theoretical concepts underlying the processes, behavior, and operation of these devices. More than 225 figures and tables illustrate the concepts, and where necessary, the theories, principles, and mathematics of some subjects are reviewed. Expert contributors discuss the analysis, synthesis, and design of nonlinear circuits; their representation, approximation, identification, and simulation; cellular neural networks; multiconductor transmission lines; and analysis and synthesis of distributed circuits.Nonlinear and Distributed Circuits builds a strong theoretical foundation for the design and analysis of both distributed and nonlinear circuits while serving as a handy reference for experienced engineers, making it a must-have for both beginners and seasoned experts.

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Lyapunov-Based Control of Robotic Systems describes nonlinear control design solutions for problems that arise from robots required to interact with and manipulate their environments. Since most practical scenarios require the design of nonlinear controllers to work around uncertainty and measurement-related issues, the authors use Lyapunov’s direct method as an effective tool to design and analyze controllers for robotic systems.After describing the evolution of real-time control design systems and the associated operating environments and hardware platforms, the book presents a host of standard control design tools for robotic systems using a common Lyapunov-based framework. It then discusses several problems in visual servoing control, including the design of homography-based visual servo control methods and the classic structure from motion problem. The book also deals with the issues of path planning and control for manipulator arms and wheeled mobile robots. With a focus on the emerging research area of human machine interaction, the final chapter illustrates the design of control schemes based on passivity such that the machine is a net energy sink.Including much of the authors’ own research work in controls and robotics, this book facilitates an understanding of the application of Lyapunov-based control design techniques to up-and-coming problems in robotics.

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Technology has spurred the growth of huge image and video libraries, many growing into the hundreds of terabytes. As a result there is a great demand among organizations for the design of databases that can effectively support the storage, search, retrieval, and transmission of video data. Engineers and researchers in the field demand a comprehensive reference that will help them design and implement the most complex video database projects.Handbook of Video Databases: Design and Applications presents a thorough overview in 45 chapters from more than 100 renowned experts in the field. This book provides the tools to help overcome the problems of storage, cataloging, and retrieval, by exploring content standardization and other content classification and analysis methods. The challenge of these complex problems make this book a must-have for video database practitioners in the fields of image and video processing, computer vision, multimedia systems, data mining, and many other diverse disciplines.

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This book provides valuable information for investigators interested in the signaling and regulatory functions of adenosine and the adenine nucleotides. Topics covered in this comprehensive volume include the historical development of research on adenosine and adenosine triphosphate; various aspects of the formation, metabolism, release, transport, and receptors for endogenous adenosine and the adenosine triphosphate; functions of purines at the cellular level; the role of adenosine in the regulation of flow in different vascular beds; and angiogenesis. The book also addresses the purinergic regulation of the cardiac, renal, gastro-intestinal, and central nervous system, as well as potential therapeutic avenues for purine use. The book will be valuable to physiologists, pharmacologists, and other basic and clinical scientists interested in updating their knowledge of the expanding biological roles of these substances.

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This book represents a comprehensive update on pulmonary surfactant by merging classical knowledge with new information. Topics include surfactant secretion and alveolar processing and recycling; physical bases and different theoretical models of the physiological mechanism for pulmonary surfactant action; recent findings on surfactant-like material in other organs; developmental processes and multifactorial regulation; etiology and physiopathology of neonatal respiratory distress; and modern methods for functional explorations of the lung in neonates and experimental models in animals. The book also contains a discussion on the management of hyaline membrane disease, from both the experimental and clinical points of view.

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Intended primarily for researchers working with bioactive substances such as hormones, neurotransmitters, growth factors, and connective tissue makers, this book discusses the principles of degradation in major groups of bioactive materials with respect to physiology, location, and regulation. Peptidases; receptor-mediated endocytosis; organ extraction and clearance; and the degradation of specific proteins, peptides, amines, steroids, and polysaccharoides are featured. Pathophysiology and its role in diagnostics and disease are considered throughout the book, in addition to updates of recent literature and substantial new information on physiology and pathophysiology of degradation of bioactive material. No special mathematical or kinetic background is necessary to read this book because the mathematic and kinetic concepts are facilitated through the presentation of fundamental and more advanced principles. Furthermore, illustrations and tables are provided to facilitate the understanding of the dynamic aspects of degradation processes. Degradation of Bioactive Substances: Physiology and Pathophysiology is the first comprehensive work describing the degradation of bioactive material, including information not found in biochemical textbooks on internal metabolism or pharmacokinetic textbooks on drug metabolism.

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This significant volume provides reviews on protein methylation reactions which occur ubiquitously in nature. Written in a comprehensive style, this work covers knowledge on the natural occurrence of methylated amino acids, their chemical synthesis, plus the enzymology, biological regulator, and biological significance of free methylated amino acids. It also includes various specific biological systems where posttranslational methylation reactions have been demonstrated. This text is unique because the chapters are critically reviewed by authorities in each respective field. This well-written volume is an excellent reference to researchers as well as graduate students interested in post-synthetic modifications of macromolecules.

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Ultrasonic Exposimetry presents the fundamentals of ultrasonics and discusses the theoretical background of acoustic wave generation and reception. Measurements, instrumentation, and interpretation of measured data (including error analysis) are examined in detail.

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Chemical Contaminants in Human Milk contains a comprehensive, up-to-date global review of the contamination of human milk with environmental and occupational chemicals. The book covers many different aspects of this problem, including the extent and benefits of breast-feeding, the transfer of chemicals into breast milk, analytical methodologies used in human milk studies, the levels of chemical contaminants in human milk, and geographical variations and time trends in levels. The many different factors that can influence the levels of contaminants in breast milk are also discussed. Other important topics examined include human milk contamination due to exposure of the mother at the workplace and the risk to her baby, the intake of toxic chemicals by breast-fed infants, calculated intakes and official limit values, the toxicological implications of human milk contamination based on available data from animal experiments and human studies. The book concludes with an overall assessment of the current situation, together with recommendations for future work. Chemical Contaminants in Human Milk is a valuable source of information for pediatricians and other health professionals, policy makers involved with ensuring the health and welfare of infants and nursing mothers, nursing mothers and organizations involved in the promotion of breast feeding, and individuals and organizations involved with the study and control of environmental pollution and occupational hygiene.

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This important new book presents critical information on the clinical and morphological aspects of various endocrinological disorders of the gut and pancreas. Topics include a historical perspective and broad overview of the neuroendocrine component of the gut; hyperplastic proliferations of gastrointestinal endocrine cells; pancreatic endocrine cells and their non-neoplastic proliferations; tumors and lesions; and endocrine differentiation in nonendocrine tumors. The book stresses clinical and pathological aspects of these topics, as well as the pathogenesis, clinicopathological correlations, and diagnostic approaches. Gastroenterologists, pathologists, internists, surgeons, endocrinologists and others interested in endocrinological disorders of the gut and pancreas will discover that this book will be a welcome addition to your reference library.

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This volume gives special reference to papillomaviruses in benign precursor lesions related to genital tumors, plus it provides a basis for a more reproducible evaluation of the pathology of papillomavirus-induced lesions. It deals with the molecular biology of papillomaviruses as it relates to our understanding of viral cell transformation and malignant conversion. Written in a comprehensive, easy-to-read format, this book covers points of medical interest such as diagnosis, therapy, and prospects for vaccination. This fascinating text provides current, state-of-the-art practices for immediate and future medical research. Virologists, microbiologists, and cancer researchers will find this work interesting and resourceful.

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Viral Fusion Mechanisms presents the first comprehensive review on this exciting topic. The book focuses on molecular mechanisms rather than phenomonology and examines a wide range of viruses, including influenza, HIV, Sendai, SFV, Vaccinia, VSV, and RSV. Recent theoretical work on dissecting protein-mediated membrane fusion is discussed, and the most promising new technologies for elucidating mechanisms are highlighted.Viral Fusion Mechanisms is an essential reference for biophysicists, cell biologists, colloid chemists, immunologists, microbiologists, molecular biologists, and virologists.

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This volume presents information and techniques which are at the leading edge of microbial acid rain research and addresses a number of topical and important issues of global concern. Topics discussed include microbial responses to low pH and biogeochemical processes. Cycling of organic matter, microbial interactions with higher forms of biota, and the factors affecting these processes and interactions are described. This book is of special interest to researchers and those involved in management of acid - stressed waters.

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Advances in Pregnancy-Related Protein Research describes the most significant advances in pregnancy-related protein research that have occurred over the last 25 years. The fetal, pregnancy, placental, and endometrial proteins discussed are classified by their origin and biological activity. The structure and function of newly discovered pregnancy protein families are examined in detail. Physiological values of various pregnancy and placental proteins are presented, and the pathophysiological significance of diagnostic and therapeutic data is addressed. Advances in Pregnancy-Related Protein Research will be a useful reference for obstetricians, oncologists, immunologists, reproduction specialists, oncodevelopmental biologists, gynecologists, and other researchers interested in the subject.

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A comprehensive and critical assessment of selenium levels in both natural and man-made materials and systems is presented in this publication. The book begins with a treatment of the chemistry and analytical chemistry of the element and an important discussion of the status and reliability of analytical data together with the approach to be followed in extracting, managing and presenting the information. An in-depth treatment of selenium is arranged according to groupings of the different materials and systems. Each chapter discusses the occurrence of selenium in and distribution among components of the specified system. Additionally, easy reference compilations of concentration data based on critical assessment of the selenium literature are provided, along with a comprehensive listing of the pertinent literature. The book concludes with chapters on the biogeochemistry of selenium in natural systems. Throughout, consideration is given to both total selenium and its compounds.

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The purpose of this 4-volume set is to examine some of the applications of lasers in polymer science and technology. Now available for the first time, up-to-date information on this fascinating subject is compiled and presented in compact form. This set focuses on current research and developments in the application of lasers in polymer and biopolymer chemistry. It includes experimental and theoretical details, apparatus, techniques, and applications. This set is a useful source for researchers, students, polymer chemists, and physicists involved in this astonishing field of high technology.

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Kinetic models are becoming standard tools in the research of biological systems. They are used to represent hypotheses, analyze data, and design experiments to maximize the information obtained from a study. Kinetic Models of Trace Element and Mineral Metabolism During Development describes models for calcium, chromium, copper, iron, iodide, lead, mercury, selenium, zinc, and others in health and disease.

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This up-to-date reference includes the most recent available data and detailed case studies concerning the potential health risks of aflatoxin in the human population. It covers everything from acute toxic effects of aflatoxin in men to original observations concerning occupational health hazards due to aflatoxin exposure via the respiratory tract. This work places special emphasis on the potential etiological role of aflatoxin in Reye's syndrome. The presence of aflatoxins in the biological material indicates that the possible carcinogenic hazard due to aflatoxin ingestion is not limited to certain areas but exists all over the world. This informative book is a must for all researchers involved in environmental pathology, food science, mycology, toxicology, and industrial safety.

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Hospitals in the US and Canada are ill-prepared for the threat of emerging infectious diseases, especially in the area of protecting healthcare workers, nurses, doctors, and first responders from transmissions. Current protocols from guideline agencies and health organizations and health departments that include state pandemic flu plans do not follow scientific evidence in many of their recommendations.Economics and 'ease of use' are trumping good science in the decision making process. For example, protocols do not demand the most stringent precautions that would protect for healthcare workers from unknown factors of transmission in the case of rapidly emerging diseases. Respiratory protection, negative pressure isolation rooms, training of healthcare workers, personal protective equipment, ventilation designs, triage of surge patients, funding issues are all areas of concern that remain controversial in current occupational health protection models. Emerging Infectious Diseases and the Threat to Occupational Health in the US and Canada offers a critical review of existing plans and infrastructures for emerging diseases and the response capabilities of healthcare delivery systems to protect the occupational health and offers many solutions. The authors perform failure analysis that cannot be found in other texts, and offer positive solutions, strategies, and tactics for strengthening the hospital and the public health response to potentially catastrophic health crises. This book contains invaluable information for managers, professionals, and policy makers in infectious disease organizations, public health organizations, as well as occupational health organizations.

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Initiation and Promotion in Skin or Liver Neoplasia is the only source of its kind that presents a comprehensive compilation of in vivo initiation/promotion studies that involve neoplastic changes in the skin or liver of experimental animals. The book surveys world literature over the past 65 years from almost 2,000 original studies covering nearly 200 journals in 9 languages. Publications reviewed consist of primary peer-reviewed papers, as well as those abstracts, meeting reports, and review articles, containing original data. Papers measuring both pre-neoplastic or neoplastic changes are included.The summaries for each study included in the book are highly formatted resumes that have four principal components which indicate:1) What was done in the study;2) How the study was done (e.g, methods);3) The precise results obtained;4) Individual critiques using GLP (Good Lab Practice) standards.Initiation and Promotion in Skin or Liver Neoplasia provides an indispensable abstracted reference resource for scientists, toxicologists, cancer researchers, litigators, regulators, environmentalists, policy analysts, and industry-based investigators.

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Covering some of the most important topics in modern toxicology, the Handbook of Human Toxicology is a unique and valuable addition to the current literature. It addresses issues, answers questions, and provides data related to. Within each of these five major sections are several carefully selected topics that reflect the current state of human toxicology. From tissue uptake of mercury to the effects of drugs on immune systems, the text provides much-needed information quickly and easily.

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This publication is rare among those texts on pesticides in that it covers herbicides exclusively. It presents, in one source, information that is typically scattered. This important publication enables the reader to recommend herbicide use more reliably and efficiently. It also highlights environmental issues relevant to herbicide use in agriculture. The book outlines potential areas of further research. This title is of particular value to weed scientists, environmental chemists and engineers, soil scientists, and those responsible for recommending and/or regulating use of herbicides in agriculture.Focuses On:? Increasing efficiency of herbicides in agriculture? Decreasing environmental contamination with herbicides? Dissipation and transformations in water and sediment? Nature, transport, and fate of airborne residues? Absorption and transport in plants? Transformations in biosphere? Bioaccumulation and food chain accumulation? Photochemical transformations? Bound residues? Predictability and environmental chemistry

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