Description
Book SynopsisNow for the first time, one comprehensive book summarizes and analyzes the numerous scientific papers and reviews covering selected aspects of the structure, biological activities, and clinical effects of immune interferon, also known as interferon-gamma(IFN-gamma). Immune Interferon: Properties and Clinical Applications is essential reading for anyone working with interferons.
Having developed their own brand of interferon-gamma, the authors have become well known for their research and significant contributions in the fields of molecular biology, biochemistry, and interferon-gamma. They bring together the extensive findings from years of research since the discovery of the drug. Focusing on the drug itself and not particular brands, the book presents data on the properties of interferon-gamma, experimental data on its effects in cell cultures in vitro and on animals in vivo, the role that IFN-gamma plays in different diseases, and the results of its clinical applications.
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Trade Review"…an excellent review of indications studied and under study and the outcomes of IFNg, as well as an exhaustive collection of references for these indications. A briefer overview of the preclinical and pharmacologic aspects of IFNg is provided."
- James E. Talmidge, Ph.D., University of Nebraska Medical School in Doody's Notes
Table of ContentsForeword. Abbreviations. The Cytokine Family.
Interferon Gamma (IFN). Biological Activities of Interferon Gamma. Molecular Mechanisms of IFN Activities. Transmembrane Signal Transduction. Production of Interferon Gamma. Gamma-Interferon Preparations. Indications and Contraindications. Routes of Administration, Pharmacokinetics, Dosage. Side Effects. Infectious Diseases. Non-Infectious Non-Malignant Diseases. Malignant Diseases. General Conclusions. References.
