Description
Book SynopsisChronic obstructive pulmonary disease (COPD), characterized by progressive chronic airflow obstruction, is the most common respiratory disorder of adults in the developed world and is the fourth main cause of death in the US. COPD has received little attention compared with other respiratory diseases such as asthma and lung cancer.
Trade Review"The panel of speakers included some of the most distinguished scientists and physicians working in the field of COPD." (Biochemie, No. 83, 2001)
Table of ContentsOverview of the pathology/pathogenesis
Overview of current therapies
Genetics
Mucus hypersecretion in COPD
Mechanisms of exacerbation
Epithelial and mesenchymal cells
Macrophage control of inflammation: negative pathways of regulation of inflammatory cytokines
Neutrophils
Lymphocytes
Oxidants/antioxidants
Proteases and anti-proteases -
I
Proteases and anti-proteases -
II
Alveolus formation: critical period, plasticity and retinoid regulation
Systemic effects of COPD
Potential novel therapies for COPD
