Search results for ""author james devillers""

Uses Computational Tools to Simulate Endocrine Disruption PhenomenaEndocrine Disruption Modeling provides a practical overview of the current approaches for modeling endocrine activity and the related potential adverse effects they may induce on environmental and human health. Based on the extensive research of an international panel of contributors from industry, academia, and regulatory agencies, this is the first book devoted to using computer tools to better understand and simulate the multifaceted aspects of endocrine disruption in humans and wildlife. Explores Diverse Modeling Techniques and ApplicationsThis up-to-date resource focuses on xenobiotics that are accidentally released into the environment with the potential to disturb the normal functioning of the endocrine system of invertebrates and vertebrates but also on the specific agro-chemistry design of chemicals that take control of insect endocrine systems. A comprehensive research reference, Endocrine Disruption Modeling provides a collection of computational strategies to model these structurally diverse chemicals. It concludes with a review of the available e-resources in the field, rounding out the book’s task-oriented approach to future EDC discovery.Endocrine Disruption Modeling is the first book in the QSAR in Environmental and Health Sciences series (James Devillers, j.devillers@ctis.fr).

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Juvenile hormones (JHs) are a group of structurally related sesquiterpenes secreted by the insect corpora allata. They affect most insect life-cycle stages and physiological functions, including embryogenesis, larval and adult development, metamorphosis, reproduction, metabolism, diapause, polyethism, and migration. Juvenoids such as methoprene, hydroprene, kinoprene, pyriproxyfen, and fenoxycarb are man-made chemicals that mimic the structure and/or activity of JHs, selectively targeting and disrupting the endocrine system of insects. They are particularly suited as larvicides for the control of pest and disease vectoring insects such as mosquitoes.Juvenile Hormones and Juvenoids: Modeling Biological Effects and Environmental Fate discusses the various modeling approaches that can be used to study the mechanism of action of JHs in insects and to estimate the adverse effects and the environmental fate of the juvenoids that mimic their activity. This book is the third of the QSAR in Environmental and Health Sciences series, but the first dedicated to the use of QSAR and other in silico techniques to provide these insights into JHs and their analogs.With contributions by an international team of scientists, the book begins with a historical survey of JHs and juvenoids. It then discusses biosynthesis of sesquiterpenoids followed by chapters covering JH activity such as morph-specific JH titers in crickets, and JH analog activity including soldier-specific organ development in termites and the role of methoprene in gene transcription. The book examines modeling approaches applied to resistance to JH analogs, to population dynamics of nontarget species in the presence of juvenoids, and to SAR and QSAR of JH mimics. The book concludes with a discussion on the use of multicriteria analysis for selecting insecticides for vector control.

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Bees are critically important for ecosystem function and biodiversity maintenance through their pollinating activity. Unfortunately, bee populations are faced with many threats, and evidence of a massive global pollination crisis is steadily growing. As a result, there is a need to understand and, ideally, predict how bees respond to pollution disturbance, to the changes over landscape gradients, and how their responses can vary in different habitats, which are influenced to different degrees by human activities.Modeling approaches are useful to simulate the behavior of whole population dynamics as well as to focus on important phenomena detrimental to bee-life history traits. They also allow simulation of how a disease or a pesticide can impact the survival and growth of a bee population. In Silico Bees provides a collection of computational methods to those primarily interested in the study of the ecology, ethology, and ecotoxicology of bees. The book presents different cases studies to enable readers to understand the significance and also the limitations of models in theoretical and applied bee research.The text covers modeling of honey bee society organization, infectious diseases in colonies, pesticide toxicity, chemical contamination of the hive, and more. Written by an international team of scientists, this book is of primary interest to those whose research or professional activity is directly concerned with the study of bees. It is also intended to provide graduate and post-graduate students with a clear and accessible text covering the main types of modeling approaches that can be used in terrestrial ecology and ecotoxicology.

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Featuring the most well-known photos from Robert Doisneau since the beginning of his career, (re)discover his talent through an original and unknown full colour photoreport. This retrospective of the works of Doisneau also give an insight in the lives of famous artists such as Picasso and Niki de Saint Phalle. The book is themed by three subjects: the main characteristics of his work and his importance for 20th century photography, the notion of the poetry of realism and 164 photos, which are also themed: daily beauty, Palm Springs, artists' studios. Published to accompany an exhibition in Musee Ixelles (Brussels) from 19 October 2017 until 4 February 2018.

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