Search results for ""author claas kirchhelle""

Winner of the 2021 Joan Thirsk Memorial Prize from the British Agricultural History Society​2020 Choice​ Outstanding Academic Title​Winner of the 2020 Turriano Prize from ICOHTECShort-listed and highly commended for the Antibiotic Guardian Award from Public Health England​Long-listed for the Michel Déon Prize from the Royal Irish Academy​Pyrrhic Progress analyses over half a century of antibiotic use, regulation, and resistance in US and British food production. Mass-introduced after 1945, antibiotics helped revolutionize post-war agriculture. Food producers used antibiotics to prevent and treat disease, protect plants, preserve food, and promote animals’ growth. Many soon became dependent on routine antibiotic use to sustain and increase production. The resulting growth of antibiotic infrastructures came at a price. Critics blamed antibiotics for leaving dangerous residues in food, enabling bad animal welfare, and selecting for antimicrobial resistance (AMR) in bacteria, which could no longer be treated with antibiotics. Pyrrhic Progress reconstructs the complicated negotiations that accompanied this process of risk prioritization between consumers, farmers, and regulators on both sides of the Atlantic. Unsurprisingly, solutions differed: while Europeans implemented precautionary antibiotic restrictions to curb AMR, consumer concerns and cost-benefit assessments made US regulators focus on curbing drug residues in food. The result was a growing divergence of antibiotic stewardship and a rise of AMR. Kirchhelle’s comprehensive analysis of evolving non-human antibiotic use and the historical complexities of antibiotic stewardship provides important insights for current debates on the global burden of AMR. This Open Access ebook is available under a CC-BY-NC-ND license, and is supported by a generous grant from Wellcome Trust.

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Winner of the 2021 Joan Thirsk Memorial Prize from the British Agricultural History Society​2020 Choice​ Outstanding Academic Title​Winner of the 2020 Turriano Prize from ICOHTECShort-listed and highly commended for the Antibiotic Guardian Award from Public Health England​Long-listed for the Michel Déon Prize from the Royal Irish Academy​Pyrrhic Progress analyses over half a century of antibiotic use, regulation, and resistance in US and British food production. Mass-introduced after 1945, antibiotics helped revolutionize post-war agriculture. Food producers used antibiotics to prevent and treat disease, protect plants, preserve food, and promote animals’ growth. Many soon became dependent on routine antibiotic use to sustain and increase production. The resulting growth of antibiotic infrastructures came at a price. Critics blamed antibiotics for leaving dangerous residues in food, enabling bad animal welfare, and selecting for antimicrobial resistance (AMR) in bacteria, which could no longer be treated with antibiotics. Pyrrhic Progress reconstructs the complicated negotiations that accompanied this process of risk prioritization between consumers, farmers, and regulators on both sides of the Atlantic. Unsurprisingly, solutions differed: while Europeans implemented precautionary antibiotic restrictions to curb AMR, consumer concerns and cost-benefit assessments made US regulators focus on curbing drug residues in food. The result was a growing divergence of antibiotic stewardship and a rise of AMR. Kirchhelle’s comprehensive analysis of evolving non-human antibiotic use and the historical complexities of antibiotic stewardship provides important insights for current debates on the global burden of AMR. This Open Access ebook is available under a CC-BY-NC-ND license, and is supported by a generous grant from Wellcome Trust.

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“Claas Kirchhelle brings the story of typhoid to life in this compelling narrative taking us from the early medical references through the dawn of microbiology, the first use of immuno-diagnostics to the amazing power of modern vaccines to control this ancient killer. It is a book that meticulously observes the story and the science behind the discoveries that underpin modern understanding of infectious disease, on which our very lives depend.” ― Prof Sir Andrew Pollard, FMedSci, Director, Oxford Vaccine Group “Typhoid is one of the classic diseases of humankind that has been with us, perhaps since humans moved out of Africa. It still persists in many places, particularly where public infrastructure is weak and impoverished. The disease has killed many significant people in history, and has imprinted on our way of thinking. This book provides a unique and eloquent discription of the disease and its continuing impact. Very relevant in the modern interconnected world.” ― Prof Gordon Dougan, FRS, FMEDSCi, Department of Medicine, University of Cambridge, Wellcome Sanger Institute. “This lively illustrated account gives typhoid the prominence it deserves and links the past with the present.” ― Dr Margaret Pelling, Centre for the History of Science, Medicine, And Technology, University of Oxford. A killer of paupers, princes and presidents, typhoid was an invisible threat in Victorian times and remains dangerous in many areas today. In this exploration of the past, present and future of typhoid control, Dr Claas Kirchhelle uses the stories of both literary characters and real-life figures to trace typhoid’s transformation from a mysterious scourge into a controllable microbial threat. Drawing on the award-winning Typhoidland exhibitions, the author dispels the myth of typhoid as an eradicated disease and shows how cutting-edge vaccines and collective international action offer new hope amidst surging drug resistance – a subject that has gained new relevance in a post-COVID world.

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