Search results for ""Springer-Verlag New York Inc.""

The goal of this book is to show how to build and manage a food safety department that is tasked with ensuring food safety within a food retail business. The experiences of the author as the head of Food and Product Safety at Chick-fil-A will be used as the model. Specifically, the book will discuss the specific components of a food safety program, the tactics needed to establish these components (forming the majority of the chapters), how to measure the success of each component, and how to influence the organization to ensure resources to support the program. The book will also focus on how to choose and work with the appropriate partners, validate the value to the business, and initiate the new component throughout the organization, including how to sustain the component within the program. Five features of this book that make it distinctive are: Most current “How to” book on leading a food safety department from the perspective of a respected national brand Provides the proper organization and methods to manage the work necessary to ensure food safety within the organization Provides the means to utilize risk-based decisions linked to business practices that accommodate a business analysis model Demonstrates step-by-step examples that can be used for continuous improvement in sustaining food safety responsibilities Provides examples on how to gain influence and obtain resources to support food safety responsibilities

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Imagine that we had some way to look directly at the molecules in a living organism. An x-ray microscope would do the trick, or since we’re dreaming, perhaps an Asimov-style nanosubmarine (unfortunately, neither is currently feasible). Think of the wonders we could witness firsthand: antibodies atta- ing a virus, electrical signals racing down nerve fibers, proteins building new strands of DNA. Many of the questions puzzling the current cadre of sci- tists would be answered at a glance. But the nanoscale world of molecules is separated from our everyday world of experience by a daunting million-fold difference in size, so the world of molecules is completely invisible. I created the illustrations in this book to help bridge this gulf and allow us to see the molecular structure of cells, if not directly, then in an artistic rendition. I have included two types of illustrations with this goal in mind: watercolor paintings which magnify a small portion of a living cell by one million times, showing the arrangement of molecules inside, and comput- generated pictures, which show the atomic details of individual molecules. In this second edition of The Machinery of Life, these illustrations are presented in full color, and they incorporate many of the exciting scientific advances of the 15 years since the first edition.

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When developmental psychologists set forth the theory that the roots of adult psychopathology could be traced to childhood experience and behavior, the idea quickly took hold. Subsequently, as significant research in this area advanced during the past decade, more sophisticated theory, more accurate research methodologies, and improved replication of empirical findings have been the result.The Third Edition of the Handbook of Developmental Psychopathology incorporates these research advances throughout its comprehensive, up-to-date examination of this diverse and maturing field. Integrative state-of-the-art models document the complex interplay of risk and protective factors and other variables contributing to normal and pathological development. New and updated chapters describe current refinements in assessment methods and offer the latest research findings from neuroscience. In addition, the Third Edition provides readers with a detailed review across the spectrum of salient topics, from the effects of early deprivation to the impact of puberty.As the field continues to shift from traditional symptom-based concepts of pathology to a contemporary, dynamic paradigm, the Third Edition addresses such key topics as: Early Childhood disorders, including failure to thrive and attachment disorders. Aggression, ADHD, and other disruptive conditions. Developmental models of depression, anxiety, self-injury/suicide, and OCD. The autism spectrum and other chronic developmental disorders. Child maltreatment and trauma disorders. The Third Edition of the Handbook of Developmental Psychopathology is a discipline-defining, forward-looking resource for researchers, clinicians, scientist-practitioners, and graduate students in such fields as developmental psychology, psychiatry, social work, child and school psychology, educational psychology, and pediatrics.<

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This book brings together examples of leading thinking and international practice in the rapidly developing area of environmental management accounting .(EMA) The authors include academics and practitioners from industry and the subjects covered range from individual company experiences with implementing EMA to national experiences regarding the adoption and diffusion of EMA practices.

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This detailed book provides an exhaustive picture of current methods to detect, isolate, and analyze extracellular vesicles (EVs) from diverse sources, now seen as potential disease biomarkers as well as tools for the development of new therapies. Beginning with a section on detection and isolation of EVs, the volume continues with chapters covering different methods to isolate and quantify EVs from specialized tissues/organs and body fluids, methods devoted to analyzing EV components, as well as cutting-edge methods to engineer EVs. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Extracellular Vesicles in Diagnosis and Therapy serves as an ideal guide for researchers seeking to learn more about the complexities of cell-to-cell communication.

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This lively introductory text exposes the student to the rewards of a rigorous study of functions of a real variable. In each chapter, informal discussions of questions that give analysis its inherent fascination are followed by precise, but not overly formal, developments of the techniques needed to make sense of them. By focusing on the unifying themes of approximation and the resolution of paradoxes that arise in the transition from the finite to the infinite, the text turns what could be a daunting cascade of definitions and theorems into a coherent and engaging progression of ideas. Acutely aware of the need for rigor, the student is much better prepared to understand what constitutes a proper mathematical proof and how to write one.Fifteen years of classroom experience with the first edition of Understanding Analysis have solidified and refined the central narrative of the second edition. Roughly 150 new exercises join a selection of the best exercises from the first edition, and three more project-style sections have been added. Investigations of Euler’s computation of ζ(2), the Weierstrass Approximation ­ Theorem, and the gamma function are now among the book’s cohort of seminal results serving as motivation and payoff for the beginning student to master the methods of analysis.

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From translating the patient’s medical records and test results to providing recommendations, the neuropsychological evaluation incorporates the science and practice of neuropsychology, neurology, and psychological sciences. The Little Black Book of Neuropsychology brings the practice and study of neuropsychology into concise step-by-step focus—without skimping on scientific quality. This one-of-a-kind assessment reference complements standard textbooks by outlining signs, symptoms, and complaints according to neuropsychological domain (such as memory, language, or executive function), with descriptions of possible deficits involved, inpatient and outpatient assessment methods, and possible etiologies. Additional chapters offer a more traditional approach to evaluation, discussing specific neurological disorders and diseases in terms of their clinical features, neuroanatomical correlates, and assessment and treatment considerations. Chapters in psychometrics provide for initial understanding of brain-behavior interpretation as well as more advanced principals for neuropsychology practice including new diagnostic concepts and analysis of change in performance over time. For the trainee, beginning clinician or seasoned expert, this user-friendly presentation incorporating ‘quick reference guides’ throughout which will add to the practice armentarium of beginning and seasoned clinicians alike. Key features of The Black Book of Neuropsychology: Concise framework for understanding the neuropsychological referral. Symptoms/syndromes presented in a handy outline format, with dozens of charts and tables. Review of basic neurobehavioral examination procedure. Attention to professional issues, including advances in psychometrics and diagnoses, including tables for reliable change for many commonly used tests. Special “Writing Reports like You Mean It” section and guidelines for answering referral questions. Includes appendices of practical information, including neuropsychological formulary. The Little Black Book of Neuropsychology is an indispensable resource for the range of practitioners and scientists interested in brain-behavior relationships. Particular emphasis is provided for trainees in neuropsychology and neuropsychologists. However, the easy to use format and concise presentation is likely to be of particular value to interns, residents, and fellows studying neurology, neurological surgery, psychiatry, and nurses. Finally, teachers of neuropsychological and neurological assessment may also find this book useful as a classroom text."There is no other book in the field that covers the scope of material that is inside this comprehensive text. The work might be best summed up as being a clinical neuropsychology postdoctoral residency in a book, with the most up to date information available, so that it is also an indispensible book for practicing neuropsychologists in addition to students and residents…There is really no book like this available today. It skillfully brings together the most important foundationsof clinical neuropsychology with the 'nuts and bolts' of every facet of assessment. It also reminds the more weathered neuropsychologists among us of the essential value of neuropsychological assessment…the impact of the disease on the patient’s cognitive functioning and behavior may only be objectively quantified through a neuropsychological assessment."Arch Clin Neuropsychol (2011) first published online June 13, 2011 Read the full review acn.oxfordjournals.org

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This book undertakes a detailed construction of Dynamic Markov Bridges using a combination of theory and real-world applications to drive home important concepts and methodologies. In Part I, theory is developed using tools from stochastic filtering, partial differential equations, Markov processes, and their interplay. Part II is devoted to the applications of the theory developed in Part I to asymmetric information models among financial agents, which include a strategic risk-neutral insider who possesses a private signal concerning the future value of the traded asset, non-strategic noise traders, and competitive risk-neutral market makers. A thorough analysis of optimality conditions for risk-neutral insiders is provided and the implications on equilibrium of non-Gaussian extensions are discussed.A Markov bridge, first considered by Paul Lévy in the context of Brownian motion, is a mathematical system that undergoes changes in value from one state to another when the initial and final states are fixed. Markov bridges have many applications as stochastic models of real-world processes, especially within the areas of Economics and Finance. The construction of a Dynamic Markov Bridge, a useful extension of Markov bridge theory, addresses several important questions concerning how financial markets function, among them: how the presence of an insider trader impacts market efficiency; how insider trading on financial markets can be detected; how information assimilates in market prices; and the optimal pricing policy of a particular market maker.Principles in this book will appeal to probabilists, statisticians, economists, researchers, and graduate students interested in Markov bridges and market microstructure theory.

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This third edition of the Handbook of Poisonous and Injurious Plants is designed to assist the clinician in the initial response to the needs of a child or adult exposed to a poisonous or injurious plant. It highlights common and important plants that lead to the adverse effects upon exposure, and it describes the mechanisms of action of the implicated toxin, clinical manifestations, and specific therapeutics, as available, for each. This truly comprehensive resource is botanically rigorous with insights from both the pharmacognosy and medical literature. At the same time, it is also for those who are interested in growing and enjoying the plants in their environment, filling in a not-often-discussed botanical and horticultural niche that goes beyond their beautiful physical appearance. Plants contain many useful chemicals that humans have used for millennia as botanical curatives. This book will help the reader understand the fine balance between a medication and a poison, why plants contain these natural substances, and their impact on the human body. With its thorough references and full-color photos of hundreds of potentially toxic and injurious plants inside and outside the home, this book is useful for identifying and addressing concerns about cultivated species and those found in the wild. This book will be of interest to botanists, horticulturists, clinicians, and naturalists as well as hikers, gardeners, and all those who simply enjoy the wonders of nature and the great outdoors.

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This comprehensive, yet user friendly, volume specifically focuses on cutaneous soft tissue tumors, one of the most challenging areas in dermatopathology. The text is richly illustrated and written in a user friendly fashion, by well-known experts in cutaneous soft tissue tumors, with an emphasis on a practical diagnostic approach. The text opens with a brief introduction on how to approach soft tissue tumors, followed by a guide to ancillary diagnostic tests and a thorough discussion of cutaneous soft tissue tumors and their non-mesenchymal mimics. The entities are described in terms of their clinical and pathologic features and differential diagnoses. Key pathologic features are summarized in a table format. Soft Tissue Tumors of the Skin will be of great value to surgical pathologists and dermatopathologists as well as residents and fellows in pathology and dermatology.

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This comprehensive guide covers the causes, characteristics, and presentations of acute kidney injury (AKI), as well as prevention and treatment. The first part of the book features chapters on the epidemiology and diagnosis of AKI. This is followed by sections on pathophysiology, clinical syndromes and patient management. Authored by leading clinicians, epidemiologists, basic scientists, and clinical trialists, this book captures the latest evidence and best practices for treating patients with AKI.

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This book on NeuroAIDS, a collection of chapters written by experts and specialists from around the world, provides a global perspective on HIV and NeuroAIDS in the field, clinic, and laboratory. The chapters address the comorbidity of HIV and other infectious agents, including Zika virus, Ebola, Chagas disease, TB and HCV. Also discussed are key topics, such as:· Molecular socioepidemiology· Global HIV and NeuroAIDS· Neuropathology· cART and blood-brain barrier penetration· HIV replicative oscillations· HIV and SIV evolution· Psychiatric comorbidities· Neurosyphilis · The examination of current and innovative models of translational research to translational effectiveness

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This self-contained introduction to modern cryptography emphasizes the mathematics behind the theory of public key cryptosystems and digital signature schemes. The book focuses on these key topics while developing the mathematical tools needed for the construction and security analysis of diverse cryptosystems. Only basic linear algebra is required of the reader; techniques from algebra, number theory, and probability are introduced and developed as required. This text provides an ideal introduction for mathematics and computer science students to the mathematical foundations of modern cryptography. The book includes an extensive bibliography and index; supplementary materials are available online.The book covers a variety of topics that are considered central to mathematical cryptography. Key topics include:classical cryptographic constructions, such as Diffie–Hellmann key exchange, discrete logarithm-based cryptosystems, the RSA cryptosystem, and digital signatures; fundamental mathematical tools for cryptography, including primality testing, factorization algorithms, probability theory, information theory, and collision algorithms; an in-depth treatment of important cryptographic innovations, such as elliptic curves, elliptic curve and pairing-based cryptography, lattices, lattice-based cryptography, and the NTRU cryptosystem. The second edition of An Introduction to Mathematical Cryptography includes a significant revision of the material on digital signatures, including an earlier introduction to RSA, Elgamal, and DSA signatures, and new material on lattice-based signatures and rejection sampling. Many sections have been rewritten or expanded for clarity, especially in the chapters on information theory, elliptic curves, and lattices, and the chapter of additional topics has been expanded to include sections on digital cash and homomorphic encryption. Numerous new exercises have been included.

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This book offers ophthalmologists and medical practitioners a concise, data-driven review of the information that is most relevant in guiding the diagnosis and management of thyroid-associated eye diseases (TED). Thyroid-Associated Eye Disease can be read in its entirety to give a perspective of the field, but also considered as a reference as clinical questions arise. The goal is to deliver data- driven guidance and discreet approaches and suggestions useful for clinical practice and decision making. Advances in diagnostic evaluation, including autoantibody assessment, are reviewed, and the diagnostic features of euthyroid TED are also discussed. All relevant aspects of treatment are covered, from the use of radioactive iodine, long-term medical therapy, and surgical thyroidectomy through to the treatment of active TED by steroids and novel biologics and the role of minimally invasive surgery. Numerous supporting images are included, and helpful checklists will aid the practitioner in treatment decision making.

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Since the inaugural publication of Pediatric Dialysis in 2004, a wide range of advances have taken place in dialysis-related care, leading to a wealth of new knowledge in the field. Pediatric Dialysis, Second Edition brings this knowledge together to provide the most comprehensive source of state-of-the-art information on the dialysis of infants, children and adolescents. With new chapters, updated chapters and references, and contemporary, unique perspectives from authors who are leaders in the global pediatric nephrology community, Pediatric Dialysis, Second Edition is, once again, an authoritative reference that will facilitate best practices in both acute and chronic dialysis. Experienced clinicians and trainees alike will find Pediatric Dialysis, Second Edition not only another valuable contribution to the literature but an indispensable guide to managing their pediatric patients on dialysis.

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This volume is the third in a series on depressive illness. The first volume, entitled Phenomenology of Depressive Illness, is devoted to a de­ scription of depressive illness from a variety of perspectives that include those of the patient, the clinician, and the psychiatric researcher. It de­ scribes the major subtypes of depressive illness and places them in the context of the life cycle. The second volume in this series is entitled Models of Depres­ sive Disorders: Psychological, Biological, and Genetic Perspectives. This volume describes several major models of depressive disorders, in­ cluding genetic, cognitive, interpersonal, intrapsychic, and neurobio­ logical models. The third and fourth volumes deal with the biology of affective disorders in detail. These volumes are distinguished by a triaxial ap­ proach. In Volume III the biology of affective disorders is described from the perspective of individual transmitter systems and neurophysi­ ologic and biologic processes. In Volume IV the biology of depression is addressed from the vantage point of symptom components of de­ pression, and similarities and differences in the biology of depression are described compared to other psychiatric disorders with clinically overlapping features such as anxiety disorders or eating disorders. The effects on biology of comorbid conditions such as anxiety, personal­ ity disorders, alcoholism, and eating disorders are reviewed. These ap­ proaches incorporate issues of state versus trait.

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This book gives a survey of astrophysics at the advanced undergraduate level, providing a physics-centred analysis of a broad range of astronomical systems. It originates from a two-semester course sequence at Rutgers University that is meant to appeal not only to astrophysics students but also more broadly to physics and engineering students. The organisation is driven more by physics than by astronomy; in other words, topics are first developed in physics and then applied to astronomical systems that can be investigated, rather than the other way around. The first half of the book focuses on gravity. The theme in this part of the book, as well as throughout astrophysics, is using motion to investigate mass. The goal of Chapters 2-11 is to develop a progressively richer understanding of gravity as it applies to objects ranging from planets and moons to galaxies and the universe as a whole. The second half uses other aspects of physics to address one of the big questions. While “Why are we here?” lies beyond the realm of physics, a closely related question is within our reach: “How did we get here?” The goal of Chapters 12-20 is to understand the physics behind the remarkable story of how the Universe, Earth and life were formed. This book assumes familiarity with vector calculus and introductory physics (mechanics, electromagnetism, gas physics and atomic physics); however, all of the physics topics are reviewed as they come up (and vital aspects of vector calculus are reviewed in the Appendix).

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This introductory text explains both the basic science and the applications of biotechnology-derived pharmaceuticals, with special emphasis on their clinical use. It serves as a complete one-stop source for undergraduate/graduate pharmacists, pharmaceutical science students, and for those in the pharmaceutical industry. The Fourth Edition will completely update the previous edition, and will also include additional coverage on the newer approaches such as oligonucleotides, siRNA, gene therapy and nanotech.

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Manual of Diagnostic and Therapeutic Techniques for Disorders of Deglutition is the first in class comprehensive multidisciplinary text to encompass the entire field of deglutition. The book is designed to serve as a treasured reference of diagnostics and therapeutics for swallowing clinicians from such diverse backgrounds as gastroenterology, speech language pathology, otolaryngology, rehabilitation medicine, radiology and others.Manual of Diagnostic and Therapeutic Techniques for Disorders of Deglutition brings together up-to-date information on state-of-the–art diagnostic and therapeutic modalities form disciplines of gastroenterology, speech language pathology, otolaryngology and radiology through contributions of 28 innovators, and master clinicians for the benefit of patients and providers alike. It concisely organizes the wealth of knowledge that exists in each of the contributing disciplines into one comprehensive information platform. Manual of Diagnostic and Therapeutic Techniques for Disorders of Deglutition provides a one-stop destination for members of all specialties to obtain state-of-the-knowledge information on advanced diagnostic modalities and management. It is an essential reference for all deglutologists.

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Number theory, spectral geometry, and fractal geometry are interlinked in this in-depth study of the vibrations of fractal strings, that is, one-dimensional drums with fractal boundary.Throughout Geometry, Complex Dimensions and Zeta Functions, Second Edition, new results are examined and a new definition of fractality as the presence of nonreal complex dimensions with positive real parts is presented. The new final chapter discusses several new topics and results obtained since the publication of the first edition.

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Focusing on the nuts and bolts of wireless network access for computers on board vehicles, this volume shows how in-car computerization now does much more than merely act as a glorified map-reader. Wireless communication is transforming road travel in ways previously undreamt of, allowing vehicles to “talk” to a wider network and monitor road conditions, potential delays and traffic congestion, all automatically. Toll payments can be made without opening the driver’s window on a cold day, while vehicles might themselves take active steps to avoid collisions. It is the connection between on-board computers and wireless access points, ubiquitous in most cities now, that is a key area of research. Moving vehicles transfer their communications to new points as they progress, and this causes delays, known as “handover latency”. In this book, new stochastic models are developed to map the disruption when connecting to 802.11 WLAN points. It details the application of stochastic tools to analyzing communication networks, as well as previous literature on handover latency and relevant mathematical modeling. Finally, it presents a scheme for monitoring traffic congestion using WLAN connectivity. This volume will be a useful addition to the libraries both of wireless communication students and those studying probability theory.

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Soils and Foundations for Architects and Engineers, Second Edition is a practical guide to the technology of soil mechanics and foundations, and the application of that technology to the design and construction process. This text provides an up-to-date overview of the classification of soils, the design of foundations, and the behavior of soils under load. Particular emphasis has been given to the subject of piles, piers, and caissons, and to the design and details of construction of basement and retaining walls. New to this edition: Expanded coverage of shear strength of soils, settlement analysis, and expansive soil. Design requirements for prestressed tiebacks, tiedowns, and rock anchors. Expansion of information on pile driving techniques including the use of the Engineering News Formula. A table of British-metric conversions. Many new solved problems and illustrations. In addition to the numerous new improvements, the author also includes: effects of high water tables on architectural and engineering considerations, design of shear keys used in the transfer of lateral earth pressure from a wall to the supporting element, various drainage alternatives to the structural treatment of adjacent footings, and much more. Soils and Foundations for Architects and Engineers, Second Edition can be used in advanced undergraduate and graduate level courses offered in architectural engineering and civil engineering, as well as be used as a reference book by practicing architects, insurance adjusters and attorneys who litigate or adjudicate claims involving soils and foundations.

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R is a powerful and free software system for data analysis and graphics, with over 5,000 add-on packages available. This book introduces R using SAS and SPSS terms with which you are already familiar. It demonstrates which of the add-on packages are most like SAS and SPSS and compares them to R's built-in functions. It steps through over 30 programs written in all three packages, comparing and contrasting the packages' differing approaches. The programs and practice datasets are available for download.The glossary defines over 50 R terms using SAS/SPSS jargon and again using R jargon. The table of contents and the index allow you to find equivalent R functions by looking up both SAS statements and SPSS commands. When finished, you will be able to import data, manage and transform it, create publication quality graphics, and perform basic statistical analyses. This new edition has updated programming, an expanded index, and even more statistical methods covered in over 25 new sections.

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The literature on equilibrium behavior of customers and servers in queuing systems is rich. However, there is no comprehensive survey of this field. Moreover, what has been published lacks continuity and leaves many issues uncovered. One of the main goals of this book is to review the existing literature under one cover. Other goals are to edit the known results in a unified manner, classify them and identify where and how they relate to each other, and fill in some gaps with new results. In some areas we explicitly mention open problems. We hope that this survey will motivate further research and enable researchers to identify important open problems. The models described in this book have numerous applications. Many examples can be found in the cited papers, but we have chosen not to include applications in the book. Many of the ideas described in this book are special cases of general principles in Economics and Game Theory. We often cite references that contain more general treatment of a subject, but we do not go into the details. we have highlighted the results For each topic covered in the book, that, in our opinion, are the most important. We also present a brief discussion of related results. The content of each chapter is briefly de­ scribed below. Chapter 1 is an introduction. It contains basic definitions, models and solution concepts which will be used frequently throughout the book.

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Expert testimony relying on scientific and other specialized evidence has come under increased scrutiny by the legal system. A trilogy of recent U.S. Supreme Court cases has assigned judges the task of assessing the relevance and reliability of proposed expert testimony. In conjunction with the Federal judiciary, the American Association for the Advancement of Science has initiated a project to provide judges indicating a need with their own expert. This concern with the proper interpretation of scientific evidence, especially that of a probabilistic nature, has also occurred in England, Australia and in several European countries. Statistical Science in the Courtroom is a collection of articles written by statisticians and legal scholars who have been concerned with problems arising in the use of statistical evidence. A number of articles describe DNA evidence and the difficulties of properly calculating the probability that a random individual's profile would "match" that of the evidence as well as the proper way to intrepret the result. In addition to the technical issues, several authors tell about their experiences in court. A few have become disenchanted with their involvement and describe the events that led them to devote less time to this application. Other articles describe the role of statistical evidence in cases concerning discrimination against minorities, product liability, environmental regulation, the appropriateness and fairness of sentences and how being involved in legal statistics has raised interesting statistical problems requiring further research.

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A revolution in working with difficult students began during the 1980s, with a dramatic shift away from dependence on simply punishing bad behavior to reinforcing desired, positive behaviors of children in the classroom. With its foundation in applied behavior analysis (ABA), positive behavior support (PBS) is a social ecology approach that continues to play an increasingly integral role in public education as well as mental health and social services nationwide. The Handbook of Positive Behavior Support gathers into one concise volume the many elements of this burgeoning field and organizes them into a powerful, dynamic knowledge base – theory, research, and applications. Within its chapters, leading experts, including the primary developers and researchers of PBS: (1) Review the origins, history, and ethical foundations of positive behavior support. (2) Report on applications of PBS in early childhood and family contexts, from Head Start to foster care to mental health settings to autism treatment programs. (3) Examine school-based PBS used to benefit all students regardless of ability or conduct. (4) Relate schoolwide PBS to wraparound mental health services and the RTI (response to intervention) movement. (5) Provide data and discussion on a variety of topics salient to PBS, including parenting issues, personnel training, high school use, poorly functioning schools, and more. This volume is an essential resource for school-based practitioners as well as clinicians and researchers in clinical child, school, and educational psychology.

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Driven by counter-terrorism efforts, marketing analysis and an explosion in online social networking in recent years, data mining has moved to the forefront of information science. This proposed Special Issue on Data Mining for Social Network Data will present a broad range of recent studies in social networking analysis. It will focus on emerging trends and needs in discovery and analysis of communities, solitary and social activities, activities in open for a and commercial sites as well. It will also look at network modeling, infrastructure construction, dynamic growth and evolution pattern discovery using machine learning approaches and multi-agent based simulations. Editors are three rising stars in world of data mining, knowledge discovery, social network analysis, and information infrastructures, and are anchored by Springer author/editor Hsinchun Chen (Terrorism Informatics; Medical Informatics; Digital Government), who is one of the most prominent intelligence analysis and data mining experts in the world.

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This is the only book that gives a rigorous and comprehensive treatment with lots of examples, exercises, remarks on this particular level between the standard first undergraduate course and the first graduate course based on measure theory. There is no competitor to this book. The book can be used in classrooms as well as for self-study.

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Transmediastinal gunshot injuries present the risk of immediately life threatening injuries. Stable patients have been evaluated by a combination of esophageal swallow and endoscopy, aortography and bronchoscopy. There is an increasing trend favoring CT scan. Unstable patients require immediate exploration, being prepared to enter both hemi-thoraces. Selected References: * Bergsland J, Karamanoukian HL, Soltoski PR, Salerno TA. Single suture forcircumflex exposure in coronary artery bypass grafting. Ann Thorac Surg.1999;68: 1428-1430. * Fedalen PA, Bard MR, Piacentino V, et al. Intraluminal shunt placement and off- pump coronary revascularization for coronary artery stab wound. J Trauma 200 1;50: 133-135 * Hanpeter DE, Demetriades D, Asensio JA, Berne TV, Velmahos G, Murraygunshot wounds. J Trauma 2000;49(4):689-695. * MacPherson D. Bullet Penetration: Modeling the dynamics and the incapacitation resulting from wound trauma. Ballistics Publications, EI Segundo, CA, 1994 * Wall MJ, Soltero E. Damage control for thoracic injuries, Surg Clin North AmI997;77(4):863-878. * Rozycki GS, Feliciano DV, Oschner MG, Knudson MM, Hoyt DB, Davis F, Hammerman D, Figueredo V, Harviel JD, Han DC, Schmidt JA. The role ofUltrasound in patients with possible penetrating cardiac wounds: aProspective multicenter study. J Trauma 1999; 46(4):543-552. * Roussseau H, Soula P, Bui B, D'Othee BJ, Massabuau P, Meites G, Concina P,Mazzerolles M, Joffre F, Otal P. Delayed treatment of traumatic ruptureof the thoracic aorta with endoluminal covered stent. Circulation 1999 Feb2; 99(4): 498-504.

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by Kurt Keutzer Those looking for a quick overview of the book should fast-forward to the Introduction in Chapter 1. What follows is a personal account of the creation of this book. The challenge from Earl Killian, formerly an architect of the MIPS processors and at that time Chief Architect at Tensilica, was to explain the significant performance gap between ASICs and custom circuits designed in the same process generation. The relevance of the challenge was amplified shortly thereafter by Andy Bechtolsheim, founder of Sun Microsystems and ubiquitous investor in the EDA industry. At a dinner talk at the 1999 International Symposium on Physical Design, Andy stated that the greatest near-term opportunity in CAD was to develop tools to bring the performance of ASIC circuits closer to that of custom designs. There seemed to be some synchronicity that two individuals so different in concern and character would be pre-occupied with the same problem. Intrigued by Earl and Andy’s comments, the game was afoot. Earl Killian and other veterans of microprocessor design were helpful with clues as to the sources of the performance discrepancy: layout, circuit design, clocking methodology, and dynamic logic. I soon realized that I needed help in tracking down clues. Only at a wonderful institution like the University of California at Berkeley could I so easily commandeer an ab- bodied graduate student like David Chinnery with a knowledge of architecture, circuits, computer-aided design and algorithms.

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This book fills the void to provide a comprehensive review of the theoretical knowledge and scope of opioid pharmacotherapy in pain medicine. While the information provided is obtainable in other major texts already in print, the present format style plus the illustrations will make easy reading and fast accessibility of information on opioids available. Information provided is based on clinical practice rather than pure experimental for use in daily practice.

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The food market is changing from a producer-controlled to a consumer-directed market. A main driving force is consumer concern about agricultural production methods and food safety. More than before, the consumer demands transparency of the production and processing chain.A food chain can be quite complex and the use of models has become indispensable to handle this complexity. Modelling tools are becoming increasingly important to guide the decisions for production of high-quality and safe agricultural foods. With the aid of models it becomes possible to control and predict quality attributes, so that product innovation can be done more efficiently. However, quality is an elusive concept, and there is always an aspect of subjectivity and uncertainty. A novel approach in the agro-food chain would be to tackle subjective elements and uncertainty in modelling by using Bayesian statistics and Bayesian Belief Networks. Bayesian approaches use prior probabilities (partly accounting for subjectivity) to estimate posterior probabilities, resulting in higher accuracy than is possible with classical statistical techniques. Thus, the variability and uncertainty in data and decisions, inherent in a complex food chain, can be dealt with.

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Molecular farming has been hailed as the "third wave" of genetically-modified organisms produced through biotechnology for the bio-based economy of the future. Unlike products of the first wave, such as herbicide resistant crop plants, which were perceived to benefit only the farmers who used them and the agrochemical companies who developed them, products of molecular farming are designed specifically for the benefit of the consumer. Such products could be purified from food or non-food organisms for a range of applications in industry, as well as animal and human health. Alternatively, the products of this technology could be consumed more directly in some edible format, such as milk, eggs, fruits or vegetables. There is a rapidly-growing interest Qn the part of the public as well as in the medical community in the role food plays in health, especially in the immunophysiological impact of food over and above the role of basic nutrition.

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Intended for advanced undergraduates and beginning graduates with some basic knowledge of optics and quantum mechanics, this text begins with a review of the relevant results of quantum mechanics, before turning to the electromagnetic interactions involved in slowing and trapping atoms and ions, in both magnetic and optical traps. The concluding chapters discuss a broad range of applications, from atomic clocks and studies of collision processes, to diffraction and interference of atomic beams at optical lattices and Bose-Einstein condensation.

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This book is intended for the statistician or student interested in becoming a statistical consultant, as well as clients who need to understand what is involved in the consulting process. It discusses different consulting environments, provides detailed descriptions of communication skills a consultant must possess, and provides concrete examples and case-studies of varying complexity. Emphasis is placed on the importance of engaging the client's understanding of the purpose and interpretation of statistical procedures.

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Preface Statistics is seldom the most eagerly anticipated course of a business student. It typically has the reputation of being a boring, complicated, and confusing mix of mathematical formulas and computers. Our goal in writing this casebook and the companion volume (Business Analysis Using Regression) was to change that impression by showing how statistics yields insights and answers interesting business questions. Rather than dwell on underlying formulas, we show how to use statistics to answer questions. Each case study begins with a business question and concludes with an answer to that question. Formulas appear only as needed to address the questions, and we focus on the insights into the problem provided by the mathematics. The mathematics serves a purpose. The material in this casebook is organized into 11 "classes" of related case studies that develop a single, key idea of statistics. The analysis of data using statistics is seldom very straightforward, and each analysis has many nuances. Part of the appeal of statistics is this richness, this blending of substantive theories and mathematics. For newcomers, however, this blend is too rich, and they are easily overwhelmed and unable to sort out the important ideas from nuances. Although later cases in these notes suggest this complexity, we do not begin that way.

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Chapter 5: Customers, Products, Services . . . . . . . . . . . . . 129 Close Customer Relations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 130 Customer Requirements. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 134 Dependence on the Customer and Risk Aspects . . . . . . . . . . . . . . . . . 135 Achieving Closeness to Customer . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139 Product and Service Spectrum . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 144 Summary. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 156 Chapter 6: Innovation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 159 What Does Innovation Mean?. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 159 High Level of Innovativeness . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 163 Driving Forces of Innovation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 172 The Origin of Innovations. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 176 Leadership and Organizational Aspects of Innovation . . . . . . . . . . . . 179 Summary. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 187 Chapter 7: Competition . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 191 Competitive Structure and Conduct . . . . . . . . . . . . . . . . . . . . . . . . . . 191 The Hidden Champions in the Light of Porter’s “Five Forces” . . . . . 195 Competitive Advantages. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 197 Sustainability of Competitive Advantages . . . . . . . . . . . . . . . . . . . . . . 203 Demonstration of Competitive Superiority . . . . . . . . . . . . . . . . . . . . 205 Competitive Edge and Costs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 207 Sparring Partners for Competitive Fitness . . . . . . . . . . . . . . . . . . . . . . 214 Excessive Competitive Orientation . . . . . . . . . . . . . . . . . . . . . . . . . . . 217 Summary. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 218 Chapter 8: Financing, Organization, and Business Environment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223 Financing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 224 Organization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 228 Contents ix Organization of the Value Chain . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 237 Business Environment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 249 Entrepreneurial Clusters. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 251 Summary. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 253 Chapter 9: Employees . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 257 Job Creation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 257 Corporate Culture . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 260 Quali?cations and Learning . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 274 Creativity of Employees . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 278 Recruiting . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 279 Summary. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 282 Chapter 10: The Leaders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 285 Structures of Ownership and Leadership . . . . . . . . . . . . . . . . . . . . . . 286 How Crucial Is Leadership? . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 289 Leadership Continuity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 289 Young to the Top . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 293 Powerful Women . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 294 Internationalization of Management . . . . . . . . . . . . . . . . . . . . . . . . . . 298 Personalities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 300 Leadership Styles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 305 Management Succession . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 306 Summary. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 310 Chapter 11: Hidden Champions: Audit and Strategy Development . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 315 What Is Strategy? . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 316 Hidden Champion Strategy: For Whom? . . . . . . . . . . . . . . . . . . . . . . 316 Hidden Champions – Audits . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 317 Strategy Development . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 325 Strategies for Value Propositions and Pricing . . . . . . . . . . . . . . . . . . . 335 Organization and Implementation . . . . . . . . . . . . . . . . . . . . . . . . . . .

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Used in undergraduate classrooms across the USA, this is a clearly written, rigorous introduction to differential equations and their applications. Fully understandable to students who have had one year of calculus, this book distinguishes itself from other differential equations texts through its engaging application of the subject matter to interesting scenarios. This fourth edition incorporates earlier introductory material on bifurcation theory and adds a new chapter on Sturm-Liouville boundary value problems. Computer programs in C, Pascal, and Fortran are presented throughout the text to show readers how to apply differential equations towards quantitative problems.

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Intended for use in college courses for prospective or in-service secondary school teachers of geometry. Designed to give teachers broad preparation in the content of elementary geometry as well as closely related topics of a slightly more advanced nature. The presentation and the modular format are designed to incorporate a flexible methodology for the teaching of geometry, one that can be adapted to different classroom settings. The basic strategy is to develop the few fundamental concepts of elementary geometry, first in intuitive form, and then more rigorously. The rest of the material is then built up out of these concepts through a combination of exposition and "guided discovery" in the problem sections. A separate volume including the solutions to the exercises is also available.

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This is a short text in linear algebra, intended for a one-term course. In the first chapter, Lang discusses the relation between the geometry and the algebra underlying the subject, and gives concrete examples of the notions which appear later in the book. He then starts with a discussion of linear equations, matrices and Gaussian elimination, and proceeds to discuss vector spaces, linear maps, scalar products, determinants, and eigenvalues. The book contains a large number of exercises, some of the routine computational type, while others are conceptual.

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This new, revised edition covers all of the basic topics in calculus of several variables, including vectors, curves, functions of several variables, gradient, tangent plane, maxima and minima, potential functions, curve integrals, Green’s theorem, multiple integrals, surface integrals, Stokes’ theorem, and the inverse mapping theorem and its consequences. It includes many completely worked-out problems.

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In the introduction to the first volume of The Arithmetic of Elliptic Curves (Springer-Verlag, 1986), I observed that "the theory of elliptic curves is rich, varied, and amazingly vast," and as a consequence, "many important topics had to be omitted." I included a brief introduction to ten additional topics as an appendix to the first volume, with the tacit understanding that eventually there might be a second volume containing the details. You are now holding that second volume. it turned out that even those ten topics would not fit Unfortunately, into a single book, so I was forced to make some choices. The following material is covered in this book: I. Elliptic and modular functions for the full modular group. II. Elliptic curves with complex multiplication. III. Elliptic surfaces and specialization theorems. IV. Neron models, Kodaira-Neron classification of special fibers, Tate's algorithm, and Ogg's conductor-discriminant formula. V. Tate's theory of q-curves over p-adic fields. VI. Neron's theory of canonical local height functions.

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This book discusses advanced statistical methods that can be used to analyse ecological data. Most environmental collected data are measured repeatedly over time, or space and this requires the use of GLMM or GAMM methods. The book starts by revising regression, additive modelling, GAM and GLM, and then discusses dealing with spatial or temporal dependencies and nested data.

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This unique text provides a geometric approach to group theory and linear algebra, bringing to light the interesting ways in which these subjects interact. Requiring few prerequisites beyond understanding the notion of a proof, the text aims to give students a strong foundation in both geometry and algebra. Starting with preliminaries (relations, elementary combinatorics, and induction), the book then proceeds to the core topics: the elements of the theory of groups and fields (Lagrange's Theorem, cosets, the complex numbers and the prime fields), matrix theory and matrix groups, determinants, vector spaces, linear mappings, eigentheory and diagonalization, Jordan decomposition and normal form, normal matrices, and quadratic forms. The final two chapters consist of a more intensive look at group theory, emphasizing orbit stabilizer methods, and an introduction to linear algebraic groups, which enriches the notion of a matrix group. Applications involving symmetry groups, determinants, linear coding theory and cryptography are interwoven throughout. Each section ends with ample practice problems assisting the reader to better understand the material. Some of the applications are illustrated in the chapter appendices. The author's unique melding of topics evolved from a two semester course that he taught at the University of British Columbia consisting of an undergraduate honors course on abstract linear algebra and a similar course on the theory of groups. The combined content from both makes this rare text ideal for a year-long course, covering more material than most linear algebra texts. It is also optimal for independent study and as a supplementary text for various professional applications. Advanced undergraduate or graduate students in mathematics, physics, computer science and engineering will find this book both useful and enjoyable.

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In a unified and carefully developed presentation, this book systematically examines recent developments in VRP. The book focuses on a portfolio of significant technical advances that have evolved over the past few years for modeling and solving vehicle routing problems and VRP variations. Reflecting the most recent scholarship, this book is written by one of the top research scholars in Vehicle Routing and is one of the most important books in VRP to be published in recent times.

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Here’s a conundrum: the U.S. health care system is the largest sector in the biggest economy in the world, and the US spends significantly more per capita on health care than any other country. Yet it ranks last among comparison nations on the major health indicators. Robert Kaplan attempts to tackle these anomalies head-on by taking the controversial position that mass markets have been created for services that may offer little or no benefit to patients. Kaplan forcefully argues that the overuse of medications and tests runs up the costs of health care, and offers potential solutions for policy makers and for patients.

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This reader-friendly second edition of Sheridan and Kratochwill’s important work offers innovative applications of CBC as an ecological, evidence-based approach. In this new edition, the authors combine best practices in consultation and problem-solving for interventions that promote and support children’s potential, teachers’ educational mission, and family members’ unique strengths. A step-by-step framework for developing and maintaining family/school partnerships takes readers from initial interviews through plan evaluation. Practical strategies illustrate working with diverse families and school personnel, improving family competence, promoting joint responsibility, and achieving other collaborative goals.

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This pocket guide provides concise discussion on the effective use of PET and PET/CT in patient management for a wide range of clinical conditions. Introductory chapters cover the fundamentals: basic science, patient preparation, and logistical considerations. The body of the guide examines the role of PET in the management of malignancies such as lymphoma, melanoma, and colorectal cancer. Additional chapters discuss use of PET for pancreatic, ovarian, and cervical cancers, sarcoma, and seminoma, and outlines cardiologic and neurologic applications. The final chapter considers the appropriateness, timing, and limitations of PET in common clinical case scenarios. Select images supplement the text.

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