Search results for ""author simon"

Endometriosis is a chronic benign estrogen-dependent disease which is characterized by the presence of endometriotic glands and stroma outside the uterine cavity. It affects women during reproductive age, but it may also be diagnosed in menopausal women. Endometriosis can be asymptomatic; but most frequently it can be responsible for pain symptoms and/or infertility, severely impacting women' quality of life. Overall, clinical presentation depends on the location of endometriotic lesions: intestinal symptoms can occur in case of bowel nodules whereas urinary symptoms can occur in case of urinary tract endometriosis. At the moment, the exact prevalence of endometriosis is unknown because its definitive diagnosis requires surgery and histological evaluation. It has been estimated that this benign chronic disease affects at least 3.6% of reproductive age women; however, its prevalence could significantly increase considering women suffering from dysmenorrhea, chronic pelvic pain and/or infertility. The etiology of endometriosis is unclear: various factors, such as multiple abnormalities of the immune system, genetic factors and environmental factors may influence women' susceptibility to develop this chronic disease. Although the gold standard for the diagnosis of endometriosis is the pathological evaluation of surgical biopsies or specimens, today transvaginal ultrasonography is largely employed to reliably identify the presence of deep infiltrating endometriosis or ovarian endometriomas. The aim of the surgery for endometriosis is to restore the normal anatomy by removing endometriotic lesions and by performing adequate removal of abdominal adhesions. However, surgery, in case of deep infiltrating implants, can be rather challenging for gynecologists due to the complexity of pelvic adhesions involving several structures and it may be characterized by rare but not negligible urological, intestinal, neurological and vascular complications. Furthermore, pain may recur after conservative surgery for endometriosis. Although surgery is obviously required in cases of ureteral stenosis, bowel occlusion or ovarian cysts with doubtful characteristics of malignancy, medical therapy, and, particularly, hormonal therapies, are the initial therapeutic approach today for most patients with endometriosis-related pain. Long-term medical therapy for endometriosis aims to minimize the production and action of estradiol, inhibiting the production of cyclic hormones from the ovaries. Numerous medical options (such as estroprogestins, progestins, gonadotropin- releasing hormones analogs and antagonists) are available for treating women with endometriosis: the choice of the most suitable compound is based on several factors, such as intensity of pain, age, desire to conceive, costs, route of administration and impact of the endometriosis on work capacity, sexual function and quality of life of each women. Currently, research is focused on finding new innovative targets to treat this benign chronic disease; in fact, it is well known that development, maintenance and progression of endometriosis depend on a variety of aberrant mechanisms including cell proliferation, immune function, apoptosis, invasion capacity and angiogenesis. The aim of this book is to give an accurate overview on pathogenesis, diagnosis and therapy of endometriosis.

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A multi-disciplinary analysis of Deleuze's theory of temporality Offers detailed historical analyses of Deleuze's theory of time in relation to the views of other key figures in Western philosophy Provides a fascinating analyses of the relationship of Deleuze's philosophy of time in comparison to ancient and contemporary physics Includes a thorough discussion of how the industrial revolution changed the nature of time Provides a ground-breaking analysis of Deleuze's concept of how film and literature change the way time is perceived Deleuze's thought on the nature of temporality developed throughout his career in reference to a complex array of concepts, thinkers and artistic works as well as natural and social phenomena. In this collection, leading international scholars elaborate on Deleuze's modification of the thought of historical figures, from the ancients - Plato, Aristotle, Plotinus, Lucretius - through to the moderns Spinoza Kant, Husserl, Nietzsche, Bergson, Simondon, Negri - as well as his use of scientific fields such as complexity theory and thermodynamics. The book shows that the philosophy of time was central to the development of Deleuze's work. In addition to discussing how time is conceptualized in Difference and Repetition and The Logic of Sense, this collection stands out for its elucidation of Deleuze's modification of the concept in his two books on cinema.

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A collection of tales by master illustrator and storyteller Sergio Toppi featuring a series of fables set in Old World Italy, and a feature-length what-if tale about the New World, speculating on a history where Christopher Columbus never made it to America. These classic works have never been published in English until now. Toppi’s influence on the modern comic industry is supported by popular legends including Frank Miller, Bill Sienkiewicz, Dave McKean, Walter Simonson, and Sean Gordon Murphy.

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At a time of unprecedented levels of change in the production of building materials and their deployment in construction, better theoretical and historical tools are needed to understand these new developments and how they are altering the practices and concepts of architecture. Building Materials offers a radical rethink of how materials, as they are constituted in architectural practice, are themselves constructed and, in turn, uncovers a vast and neglected resource of architectural writing about materials as they are mobilized in architecture. The book is unique in conceiving architectural specification as a starting point for architectural theory, arguing that how materials are prescribed - through a range of practices from the literal processes of procurement and manufacture to epistemological, contractual, social and economic frameworks - radically alters their potential in architecture. Drawing on the work of French philosopher Gilbert Simondon, as well as close readings of everyday specifications from the 18th to 21st centuries, the book reveals that materials do not pre-exist their shaping or use in the world, but come into being through the processes that constitute them. The book addresses three distinct methods of specification each through the lens of a different material – ‘naming’ through timber, ‘process-based’ through concrete, and ‘performance specification’ through glass – in turn revealing how the process of architectural specification (or ‘Preliminary Operations’ as Simondon puts it) allows for the development of specific relationships between material and function.

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Master illustrator and storyteller Sergio Toppi turns his massive talent toward speculative science-fiction and fantasy in this new collection of nine short stories exploring where mankind may be headed and how it connects us to where we've been before. These classic works have never been published in English until now. Toppi’s influence on the modern comic industry is supported by popular legends including Frank Miller, Bill Sienkiewicz, Dave McKean, Walter Simonson, and Sean Gordon Murphy.

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A sweet and simple introduction to Inuit hunting practices and the proper treatment of game. Nutaraq and Simonie are eager to go on their first hunting trip with their father. As they load up their snow machine and sled for the trip, Nutaraq hopes that she will be able to catch her first caribou that weekend, with some help from her dad. But when the trip nears its end and Nutaraq still hasn't caught her first caribou, she tries her very hardest to follow all of her father's advice about how Inuit traditionally hunted on the land. This book focuses not only on basic, practical hunting techniques, but also on traditional values around the treatment of animals and the sharing of food.

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A lonely squirrel goes searching for a new home, only to discover that the best place is one where the whole community can live together. Joining Barefoot's acclaimed collection of social-emotional titles, this tale offers the perfect opportunity to start conversations about coping with loneliness, the importance of community, and what makes a place feel like home. Beautiful illustrations by award-winning Italian artist Simona Mulazzani bring Squirrel's journey to life.

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Teil 1 Ein paar Grundlagen vorweg.- 1 Normgrundlagen DIN EN ISO 50001.- 2 Andere Energiemanagementsysteme.- 3 Integrierte Managementsysteme.- Teil 2  Die Auslegung der DIN EN ISO 50001.- 4 Was beeinflusst das Energiemanagementsystem.- 5 Aufgaben der Geschäftsleitung im Energiemanagementsystem.- 6 Nicht einfach drauf los.- 7 Was den Betrieb am Laufen hält.- 8 Energiesparend Produkte herstellen und Leistung erbringen.- 9 Wie gut sind wir denn.- 10 Besser geht immer.

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After the Great War, there was much debate in the USA whether the country should isolate itself from old world' conflicts or follow an imperialist path and become the world's only super-power. If the USA was to become a super-power, then conflict with Great Britain might result. Consequently, the US drew up War Plan Red. This was a scheme for the USA to invade Canada and the Caribbean which would draw the Royal Navy into North American waters where it would be destroyed. Without the Royal Navy, the rest of the British Empire would be vulnerable to American attacks. It became clear, however, as the decade wore on, that the Imperialists were not going to gain a clear-cut victory, so other means of achieving their aims would be needed. In 1939 the American military establishment created an intelligence-gathering machine within their Embassy in London under the Ambassadorship of Joseph Patrick Kennedy. Then in spring 1941, a small group of US Army officers travelled to Britain to plan for Anglo-American cooperation should the United States became involved in the Second World War. This was the US Army Special Observer Group, or SPOBS as it was commonly known. It is questionable whether the Military Attach s and SPOBS activities were spying', for they were operating - at least in the early days - with the full permission and knowledge of the British Government. Their intelligence-gathering activities spread out as far as the Middle East, Africa, South America, Russia and Asia - far beyond the terms of the original brief. It did not cease with the outbreak of peace - the advent of the Cold War between East and West brought forth a whole new range of subterfuge and behind-the-scenes activities by the CIA. So, were the Americans allies or spies? Certainly, the SPOBS bled Great Britain white of data and information, sending it all back to the War Department in Washington under the guise of helping. It was also a blueprint that America used in one form or another to encourage' regime change around the world through the seventy years or so after the Second World War and which continues to this day.

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The President is dead.Cal Drummond is hiding out deep in the woods of the American South when he hears the news. Once a famous talk show host, he is now a disgraced man living a solitary existence in a cabin, drinking Jack Daniels, enjoying the cover of the trees, and getting on with life as Hank MacPhearson.But this news and the journalist who delivers it will have consequences that reach far back into Cal's past. They threaten his new life and identity, but they also throw him one final chance: it was an interview that brought about his downfall, but could it be another one, this time with him in the hotseat, that could bring him back to life?Taking the reader from Scotland to Mexico and from California to Georgia, The Interview is a novel not only about speaking truth to power, but also about speaking truth to oneself.

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It was hoped that by paying forest dependent peoples and countries for their 'service' of conserving their forests, REDD+ would lead to a reduction in deforestation greenhouse gases. The complexities have, however, left some ambiguities. It was never agreed who would pay for the programme, and it has been criticised as ignoring the root causes of forest loss. Considering the motivations of those who promoted REDD+ this book proposes remedies to its shortfalls and recommends more efficient, equitable and effective conservation policies.Describing REDD+ from an agency perspective, this book provides a first-hand account of how individuals and institutions influenced international negotiations. It offers a comparative analysis of REDD+ as a forest conservation regime and of the way it was incorporated into the 2015 Paris agreements. In doing so, this book shows how contextual inequalities and power imbalances can result in international regimes which favour the economically powerful, and proposes providing greater roles for the assumed beneficiaries of environmental agreements in negotiations.This is an excellent introduction to REDD+, its background and execution, and will be a vital resource for students of international environmental governance, as well as for academics and researchers working on REDD+, forest policy and international governance in general.

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A Cultural History of Peace presents an authoritative survey from ancient times to the present. The set of six volumes covers over 2500 years of history, charting the evolving nature and role of peace throughout history. This volume, A Cultural History of Peace in the Medieval Age explores peace from 800 to 1450. As with all the volumes in the illustrated Cultural History of Peace set, this volume presents essays on the meaning of peace, peace movements, maintaining peace, peace in relation to gender, religion and war and representations of peace. A Cultural History of Peace in the Medieval Age is the most authoritative and comprehensive survey available on peace in the medieval era.

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Oxford student Jillian Leigh works day and night to keep up with her studies-so to leave at the beginning of the term is next to impossible. But after her uncle Toby, a renowned ghost hunter, is killed in a fall off a cliff, she must drive to the seaside village of Rothewell to pack up his belongings. Almost immediately, unsettling incidents-a book left in a cold stove, a gate swinging open on its own-escalate into terrifying events that convince Jillian an angry spirit is trying to enter the house. Is it Walking John, the two-hundred-year-old ghost who haunts Blood Moon Bay? And who beside the ghost is roaming the local woods at night? If Toby uncovered something sinister, was his death no accident? The arrival of handsome Scotland Yard inspector Drew Merriken, a former RAF pilot with mysteries of his own, leaves Jillian with more questions than answers-and with the added complication of a powerful, mutual attraction. Even as she suspects someone will do anything to hide the truth, sh

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'Old poisons decanted into new bottles': where does criticism of Israel end and where does antisemitism begin?

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The Boeing B-29 Superfortress was a four-engined heavy bomber flown primarily by the United States in World War Two and the Korean War. The B-29 remained in service in various roles throughout the 1950s. The British Royal Air Force flew the B-29 and used the name Washington for the type, and the Soviet Union produced an unlicensed copy as the Tupolev Tu-4. The name Superfortress was derived from that of its well-known predecessor, the B-17 Flying Fortress. The B-29 was the progenitor of a series of Boeing-built bombers, reconnaissance aircraft, trainers and tankers including the variant, B-50 Superfortress. The B-29 was one of the largest aircraft to see service during World War Two. A very advanced bomber for its time, it included features such as pressurized cabins, an electronic fire-control system and remote-controlled machine-gun turrets. Though it was designed as a high-altitude daytime bomber, in practice it actually flew more low-altitude nighttime incendiary bombing missions

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What does it mean to be human? What does it mean to be a human at work? The answer to these questions should not be dissimilar - to have a purpose, to connect and to feel, and yet organizational cultures still do not embrace people bringing their whole selves to work. If we are not showing up, not bringing our whole awesome selves, we are not thriving; we are hiding. The workplace and leadership are the root cause and fuel of so many societal issues, from wellbeing, the economy, inequality and the climate. Following the year of the largest remote working experiment, not many would argue against work not being somewhere we go but what we do and why we do it. The Human-Centric Workplace is about highlighting that we can do better, and we must do better. There are numerous ideas and theories about how and why people are what make organizations thrive (or expire) and yet we still fail to ensure organizations are human-centric. Culminating with a playbook, The Human-Centric Workplace aims to inform, inspire and drive change through demystifying the 'how' to ensure our people, communities and planet thrive.

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This collection of essays from a range of philosophers and art practitioners offers tools through which we can action change across art and philosophy, across a range of media and across the theory/practice divide. Including insights from contemporary Middle Eastern art to Indigenous ritual art and from feminist and queer art to architectural algorithms, this collection will decolonise your thinking about art - bypassing the traditional Western-centred art history. The first section includes theoretical essays on the concept of multiplicities, on affect and politics as well as the thought of Raymond Ruyer and Gilbert Simondon - 2 key influences on Deleuze and Guattari. The second section includes applied essays on specific art practices including the plastic arts, theatre, architecture, music and folk performances.

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Reified Life addresses the most pressing political question of the 21st century: what forms of life are free and what forms are perceived legally and economically as surplus or expendable, human and otherwise. The 2008 economic crisis solidified the dominion of neoliberal and financial capital to organize human societies much to the detriment of the world’s populations. Reified Life theorizes the dangerous social implications of a posthuman future, whereby human agency is secondary to algorithmic processes, digital protocols, speculative financial instruments, and nonhuman market and technological forces. Employing new readings of Deleuze, Guattari, Foucault, Marx, Vico, Gramsci, Berardi, and Gilbert Simondon, Narkunas contends that it is premature to speak of a posthuman or inhuman future, or employ an ‘ism, given how dynamic and contingent human practices and their material figurations can be. Over several chapters he diagnoses the rise of “market humans,” the instrumentalization of culture to decide the life worth living along utilitarian categories, and the varied ways human rights and humanitarianism actually throw members of the species like refugees outside the human order. To combat this, Reified Life argues against Reified Life calls to abandon the human and humanism, and instead proposes the ahuman to think alongside the human, what philosopher Gilbert Simondon calls the transindividuation of ontogentic processes rather than subjectivity. To aid the “figurating animal,” Reified Life elaborates speculative fictions as critical mechanisms for envisioning alternative futures and freedoms from the domineering forces of speculative capital, whose fictions have become our realities. Narkunas offers, to that end, a novel interpretation of the post-anthropocentric turn in the humanities by linking the diminished centrality of humanism to the waning dominion of nation-states over their populations and the intensification of financial capitalism, which reconfigures politics along economic categories of risk management.

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This challenging book argues convincingly that research on European integration has lagged behind important theoretical developments in the fields of international relations, international political economy, and international organization. The contributors contend that prevailing theories of integration—despite their considerable differences—all suffer from an excessive focus on institutions and ideas, while overlooking the ways in which these institutions and ideas have promoted a neoliberal agenda during the last decade. To overcome these weaknesses, this volume draws on one of the key strands of theoretical innovation—critical political economy or transnational historical materialism—to develop a more comprehensive and consistent analysis of processes of European integration. Although not claiming that states have ceded their role as "masters of the treaties," the contributors develop innovative case studies of national and transnational processes to illustrate the salience of trans-European business networks and the primacy of neoliberalism as central organizing concepts of the post-Maastricht European project. Contributions by: Baastian van Apeldoorn, Hans-Jürgen Bieling, Alan W. Cafruny, Ben Clift, Stephen Gill, Colin Hay, Otto Holman, Henk Overbeek, Kees van der Pijl, Magnus Ryner, Thorsten Schulten, Giles Scott-Smith, Leila Simona Talani, and Matthew Watson.

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This first book-length study of physico-theology questions the widespread notion of a steadily advancing early modern separation of religion and science.Beginning around 1650, the emergence of a number of new scientific concepts, methods, and instruments challenged existing syntheses of science and religion. Physico-theology, which embraced the values of personal, empirical observation, was an international movement of the early Enlightenment that focused on the new science to make arguments about divine creation and providence. By reconciling the new science with Christianity across many denominations, physico-theology played a crucial role in diffusing new scientific ideas, assumptions, and interest in the study of nature to a broad public. In this book, sixteen leading scholars contribute a rich array of essays on the terms and scope of the movement, its scientific and religious arguments, and its aesthetic sensibilities.Contributors: Ann Blair, Simona Boscani Leoni, John Hedley Brooke, Nicolas Brucker, Katherine Calloway, Kathleen Crowther, Brendan Dooley, Peter Harrison, Barbara Hunfeld, Eric Jorink, Scott Mandelbrote, Brian W. Ogilvie, Martine Pécharman, Jonathan Sheehan, Anne-Charlott Trepp, Rienk Vermij, Kaspar von Greyerz

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For the first time in English, the introductory volume in a major French philosopher’s groundbreaking series of poetic transdisciplinary works Michel Serres is recognized as one of the giants of postwar French philosophy of knowledge, along with Gilles Deleuze, Jacques Derrida, Michel Foucault, and Gilbert Simondon. His early five-volume series Hermes, which appeared in the 1960s and 1970s, was an intellectual supernova in its proposition that culture and science shared the same mythic and narrative structures. Hermes I: Communication marks the start of a major publishing endeavor to introduce this foundational series into English. Building on the figure of the Greek god Hermes, who presides over the realms of communication and interpretation, Hermes I embarks on a reflection concerning the history of mathematics via Descartes and Leibniz and culminates by way of a Bachelardian logoanalytic reading of Homer, Dumas, Molière, Verne, and the story of Cinderella. We observe a singular poetic philosopher seeking to bridge the gap between the liberal arts and the sciences through a profound mathematical and poetic fable regarding information theory, history, and art, establishing a new way to think about the production of knowledge during the late twentieth century. In these pages, students and scholars of philosophy will discover an extraordinary project of thought as vital to critical reflection today as it was fifty years ago.

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This special issue of Ethnologia Europaea focuses on tour guides as cultural mediators. It opens with a discussion of tour guiding in the anthropology of tourism by Jackie Feldman and Jonathan Skinner and consideration of how tour guiding should be seen as imaginative and performative practice. This is illustrated by a highly international and comparative collection by leading anthropologists and ethnologists, many of whom have guiding experience themselves: Valerio Simoni on intimacy, informality and sexuality in guiding relations in Cuba; David Picard on modern guiding and traditional values in La Réunion; Jackie Feldman on Jewish-Israelis guiding Christian pilgrims in the Holy Land; Amos Ron and Yotam Lurie on the intimacy and trust in guide -- tourist relations in Israel; Annelou Ypeij, Eva Krah and Floor van der Hout on the impact of gender on guide -- local relations in Peru; Irit Dekel on the manipulation of the past and the present in home museums in Germany; Jonathan Skinner on the imagination and props involved in the re-animation of heritage in a historical fantasy home in the UK. The issue ends with discussion commentaries from Noel Salazar and Erik Cohen that reiterate tour guiding as a particularly temporal and physical mediating pursuit, one which raises critical questions as to the future mechanics of tour guiding and how a performative approach to guiding engages with authenticity and new technologies.

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