Search results for ""springer international publishing ag""

This volume covers recent advances in the chemistry of ylidic compounds with focus on their application in the design of ligands with unique donor properties, the development of novel organic transformations as well as the use of ylides in homogenous catalysis. Thereby, this volume particularly aims at the community of organic and organometallic chemists engaged in synthetic chemistry and catalysis as well as in the use of special ligands for the stabilization of unusual main group element species and the “transition-metal free” activation of element-element/hydrogen bonds. These fields of research are highly active and vivid research areas to which ylide chemistry has only recently started to contribute, but has already led to fascinating developments in most different directions. This volume highlights these recent developments, thus giving not only an overview over the past achievements, but also possibilities for future applications. To this end, the chapters selected in this volume combine different aspects of ylide chemistry, starting with theoretical aspects in ligand design followed by synthetic organic methods, catalytic transformations and complex chemistry.

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This book develops the mathematical tools essential for students in the life sciences to describe interacting systems and predict their behavior. From predator-prey populations in an ecosystem, to hormone regulation within the body, the natural world abounds in dynamical systems that affect us profoundly. Complex feedback relations and counter-intuitive responses are common in nature; this book develops the quantitative skills needed to explore these interactions. Differential equations are the natural mathematical tool for quantifying change, and are the driving force throughout this book. The use of Euler’s method makes nonlinear examples tractable and accessible to a broad spectrum of early-stage undergraduates, thus providing a practical alternative to the procedural approach of a traditional Calculus curriculum. Tools are developed within numerous, relevant examples, with an emphasis on the construction, evaluation, and interpretation of mathematical models throughout. Encountering these concepts in context, students learn not only quantitative techniques, but how to bridge between biological and mathematical ways of thinking. Examples range broadly, exploring the dynamics of neurons and the immune system, through to population dynamics and the Google PageRank algorithm. Each scenario relies only on an interest in the natural world; no biological expertise is assumed of student or instructor. Building on a single prerequisite of Precalculus, the book suits a two-quarter sequence for first or second year undergraduates, and meets the mathematical requirements of medical school entry. The later material provides opportunities for more advanced students in both mathematics and life sciences to revisit theoretical knowledge in a rich, real-world framework. In all cases, the focus is clear: how does the math help us understand the science?

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This book provides learners with a unique opportunity by virtue of the format outlined above. Each case presentation has a case vignette, which leads up to an important clinical question, and is followed by additional discussion which resolves the question posed. This is a new way to present knowledge in a medical book and should help critical care practitioners, fellows, residents, allied health professionals and students expand their critical care knowledge in an efficient and effective manner. This approach should also benefit those preparing for board examinations.

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This book contains papers of the 5th International Symposium on Experimental Mechanics (5-ISEM) and the 9th Symposium on Optics in Industry (9-SOI), whose general theme is Emerging Challenges for Experimental Mechanics in Energy and Environmental Applications. These symposia are organized by Centro de Investigaciones en Optica (CIO) and Mexican Academy for Optics (AMO), under the sponsorship of the Society of Experimental Mechanics (SEM) and other national and international Organizations; Symposia are interdisciplinary forums for engineers, technicians, researchers and managers involved in all fields of Optics, Opto-mechatronics, Mechanics and Mechanical Engineering.· Addresses a broad readership including graduate and postgraduate students, researchers, and engineers working in experimental mechanics and in the application of optical methods · Covers a broad spectrum of topics highlighting the use of optical methods in experimental mechanics, energy, and in the environment

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This book introduces materials and how advances in materials result in advances in technology and our daily lives. Each chapter covers a particular material, how the material was discovered or invented, when it was first used, how this material has impacted the world, what makes the material important, how it is used today, and future applications. The list of materials covered in this book includes stone, wood, natural fibers, metals, clay, lead, iron, steel, silicon, glass, rubber, composites, polyethylene, rare earth magnet, and alloys.

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This textbook introduces readers to real analysis in one and n dimensions. It is divided into two parts: Part I explores real analysis in one variable, starting with key concepts such as the construction of the real number system, metric spaces, and real sequences and series. In turn, Part II addresses the multi-variable aspects of real analysis. Further, the book presents detailed, rigorous proofs of the implicit theorem for the vectorial case by applying the Banach fixed-point theorem and the differential forms concept to surfaces in Rn. It also provides a brief introduction to Riemannian geometry. With its rigorous, elegant proofs, this self-contained work is easy to read, making it suitable for undergraduate and beginning graduate students seeking a deeper understanding of real analysis and applications, and for all those looking for a well-founded, detailed approach to real analysis.

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This volume reviews the current research focused on the functional importance of unfolded protein response (UPR) signaling in the context of health and disease. The chapters present cutting-edge work describing the diverse functions of UPR signaling critical for regulating cellular and organismal physiology under physiologic and pathologic conditions. Written by internationally respected scientists, this volume is designed to provide a broad view of the diverse functional importance of UPR, and as such appeals to clinicians and academic researchers alike.

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This book offers a rigorous yet elementary approach to quantum mechanics that will meet the needs of Master’s-level Mathematics students and is equally suitable for Physics students who are interested in gaining a deeper understanding of the mathematical structure of the theory. Throughout the coverage, which is limited to single-particle quantum mechanics, the focus is on formulating theory and developing applications in a mathematically precise manner. Following a review of selected key concepts in classical physics and the historical background, the basic elements of the theory of operators in Hilbert spaces are presented and used to formulate the rules of quantum mechanics. The discussion then turns to free particles, harmonic oscillators, delta potential, and hydrogen atoms, providing rigorous proofs of the corresponding dynamical properties. Starting from an analysis of these applications, readers are subsequently introduced to more advanced topics such as the classical limit, scattering theory, and spectral analysis of Schrödinger operators. The main content is complemented by numerous exercises that stimulate interactive learning and help readers check their progress.

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This book examines the extensive changes in markets, technologies and value chains that telecommunication companies are currently confronted with. It analyzes the crossroads they have reached and the choices that now need to be made – to be a bit pipe or a trendsetter of digitalization. Based on an analysis of the key challenges for telcos, the book derives future market scenarios and puts forward recommendations for how they can successfully position themselves. It proposes a framework based on seven “levers,” which addresses concrete measures in each step of the value chain, ranging from technology, IT and processes, to innovation, marketing and sales issues. The book discusses the current challenges and provides both general recommendations and concrete solutions. Respected experts illustrate innovative strategic and technical trends and provide insights gained in real-life transformation projects. Recent developments in the areas of regulation, product development, competition between over-the-top (OTT) providers and telcos, as well as technical innovations like 5G, SDN/NFV, LEO satellites and MEC are discussed. Accordingly, practitioners, managers and researchers alike will benefit from the book’s wealth of examples and up-to-date insights.

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This book is a comprehensive guide to extracorporeal stone wave lithotripsy (ESWL) that includes a step-by-step approach for treating every possible kidney stone position. The book has an easy to read structure that will help readers understand ESWL quickly.Written by leading experts who have used ESWL to treat over 23000 patients, this book brings together years of practical knowledge and expertise in one concise volume. The book aims to utilise this knowledge and allow people to independently carry out kidney stone treatment on patients. Diagrams and illustrations show the methods and techniques needed in ESWL, as well as the potential complications.

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Intended as a text for upper-division undergraduates, graduate students and as a potential reference, this broad-scoped resource is extensive in its educational appeal by providing a new concept-based organization with end-of-chapter literature references, self-quizzes, and illustration interpretation. The concept-based, pedagogical approach, in contrast to the classic discipline-based approach, was specifically chosen to make the teaching and learning of plant anatomy more accessible for students. In addition, for instructors whose backgrounds may not primarily be plant anatomy, the features noted above are designed to provide sufficient reference material for organization and class presentation. This text is unique in the extensive use of over 1150 high-resolution color micrographs, color diagrams and scanning electron micrographs. Another feature is frequent side-boxes that highlight the relationship of plant anatomy to specialized investigations in plant molecular biology, classical investigations, functional activities, and research in forestry, environmental studies and genetics, as well as other fields. Each of the 19 richly-illustrated chapters has an abstract, a list of keywords, an introduction, a text body consisting of 10 to 20 concept-based sections, and a list of references and additional readings. At the end of each chapter, the instructor and student will find a section-by-section concept review, concept connections, concept assessment (10 multiple-choice questions), and concept applications. Answers to the assessment material are found in an appendix. An index and a glossary with over 700 defined terms complete the volume.

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This book elucidates what it means to transition to alternative sources of energy and discusses the potential for this energy transition to be a more democratic process. The book dynamically describes a recent sociotechnical study of a number of energy transitions occurring in several countries - France, Germany and Tunisia, and involving different energy technologies - including solar, on/off-shore wind, smart grids, biomass, low-energy buildings, and carbon capture and storage. Drawing on a pragmatist tradition of social inquiry, the authors examine the consequences of energy transition processes for the actors and entities that are affected by them, as well as the spaces for political participation they offer. This critical inquiry is organised according to foundational categories that have defined the energy transition - ‘renewable’ energy resources, markets, economic instruments, technological demonstration, spatiality (‘scale’) and temporality (‘horizon(s)’). Using a set of select case studies, this book systematically investigates the role these categories play in the current developments in energy transitions.

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This book reports on advanced concepts in fuzzy graph theory, showing a set of tools that can be successfully applied to understanding and modeling illegal human trafficking. Building on the previous book on fuzzy graph by the same authors, which set the fundamentals for readers to understand this developing field of research, this second book gives a special emphasis to applications of the theory. For this, authors introduce new concepts, such as intuitionistic fuzzy graphs, the concept of independence and domination in fuzzy graphs, as well as directed fuzzy networks, incidence graphs and many more.

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This book presents the most important advances in the class of topological materials and discusses the topological characterization, modeling and metrology of materials. Further, it addresses currently emerging characterization techniques such as optical and acoustic, vibrational spectroscopy (Brillouin, infrared, Raman), electronic, magnetic, fluorescence correlation imaging, laser lithography, small angle X-ray and neutron scattering and other techniques, including site-selective nanoprobes. The book analyzes the topological aspects to identify and quantify these effects in terms of topology metrics. The topological materials are ubiquitous and range from (i) de novo nanoscale allotropes of carbons in various forms such as nanotubes, nanorings, nanohorns, nanowalls, peapods, graphene, etc. to (ii) metallo-organic frameworks, (iii) helical gold nanotubes, (iv) Möbius conjugated polymers, (v) block co-polymers, (vi) supramolecular assemblies, to (vii) a variety of biological and soft-matter systems, e.g. foams and cellular materials, vesicles of different shapes and genera, biomimetic membranes, and filaments, (viii) topological insulators and topological superconductors, (ix) a variety of Dirac materials including Dirac and Weyl semimetals, as well as (x) knots and network structures. Topological databases and algorithms to model such materials have been also established in this book. In order to understand and properly characterize these important emergent materials, it is necessary to go far beyond the traditional paradigm of microscopic structure–property–function relationships to a paradigm that explicitly incorporates topological aspects from the outset to characterize and/or predict the physical properties and currently untapped functionalities of these advanced materials. Simulation and modeling tools including quantum chemistry, molecular dynamics, 3D visualization and tomography are also indispensable. These concepts have found applications in condensed matter physics, materials science and engineering, physical chemistry and biophysics, and the various topics covered in the book have potential applications in connection with novel synthesis techniques, sensing and catalysis. As such, the book offers a unique resource for graduate students and researchers alike.

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This book presents the design methodology and electrical diagrams of symmetrical six-phase windings, the main elements of the six-phase that are being developed to help meet the demand for high power electric drive systems that are resilient and energy efficient. Chapters are fully illustrated and include detailed tables that provide a comprehensive analysis of energy exchange processes ranging from electrical to magnetic and reveal the advantages of such windings against analogical three-phase windings.

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This book presents current trends that are dominating technology and society, including privacy, high performance computing in the cloud, networking and IoT, and bioinformatics. By providing chapters detailing accessible descriptions of the research frontiers in each of these domains, the reader is provided with a unique understanding of what is currently feasible. Readers are also given a vision of what these technologies can be expected to produce in the near future. The topics are covered comprehensively by experts in respective areas. Each section includes an overview that puts the research topics in perspective and integrates the sections into an overview of how technology is evolving. The book represents the proceedings of the International Symposium on Sensor Networks, Systems and Security, August 31 – September 2, 2017, Lakeland Florida.

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Type IV secretion systems (T4SSs) are highly versatile membrane-associated transporter machines used by Gram-negative and Gram-positive bacteria to deliver substrate molecules to a large variety of target cells. This volume summarizes our current knowledge of the large variety and structural diversity of T4SSs in pathogenic Escherichia, Agrobacterium, Legionella, Coxiella, Bartonella, Helicobacter, Enterococcus and other species. Divided into 13 chapters contributed by leading experts, it presents findings that significantly enhance our understanding of how various pathogens manipulate host cell functions to trigger bacterial uptake, promote intracellular growth, suppress defense mechanisms and of how bacteria spread antibiotic resistances, thus facilitating bacterial colonization and disease development. The book is an invaluable source of information for researchers and clinicians.

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This book contains advice and direction for women who are either seeking a career or who have already embarked on a career in financial services. The book first aims to help the female reader gain clarity on her motivation in pursuing a career in finance. It then identifies potential gender-specific challenges that could create problems if she is unaware or unconscious to her surrounding work environment. Lastly, it provides insights and exercises to develop a strategy for career accomplishment. Written by a former Senior Financial Executive for several fortune 500 firms including M&M Mars, a Wealth Manager/Owner of a fee-only Registered Investment Advisory firm, and Professor of financial planning at the University of South Florida, the book will help women identify pitfalls, create game plans to transcend the limitations of their workplace cultures, and learn how to collaborate with their peers to create healthier work environments. Told through personal stories, anecdotes from other women and academic research, Gender on Wall Street helps women identify the internal and external obstacles to their success. This book will also provide a means of overcoming these obstacles through conscious engagement, personal reflection and strategy-building exercises at the conclusion of each chapter. The reader will be guided into creating their own personal career plan—the STAR plan—which will help them achieve career success.

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The Cambridge Workshops on Universal Access and Assistive Technology (CWUAAT) is one of the few gatherings where people interested in inclusive design, across different fields, including designers, computer scientists, engineers, architects, ergonomists, ethnographers, policymakers and user communities, meet, discuss, and collaborate. CWUAAT has also become an international workshop, representing diverse cultures including Portugal, Germany, Trinidad and Tobago, Canada, Australia, China, Norway, USA, Belgium, UK, and many more. The workshop has five main themes based on barriers identified in the developing field of design for inclusion: I Breaking Down Barriers between Disciplines II Breaking Down Barriers between Users, Designers and Developers III Removing Barriers to Usability, Accessibility and Inclusive Design IV Breaking Down Barriers between People with Impairments and Those without V Breaking Down Barriers between Research and Policy-making In the context of developing demographic changes leading to greater numbers of older people and people living with impairments, the general field of inclusive design research strives to relate the capabilities of the population to the design of products, services, and spaces. CWUAAT has always had a successful multidisciplinary focus, but if genuine transdisciplinary fields are to evolve from this, the final barriers to integrated research must be identified and characterised. Only then will benefits be realised in an inclusive society. Barriers do not arise from impairments themselves, but instead, are erected by humans, who often have not considered a greater variation in sensory, cognitive and physical user capabilities. Barriers are not only technical or architectural, but they also exist between different communities of professionals. Our continual goal with the CWUAAT workshop series is to break down barriers in technical, physical, and architectural design, as well as barriers between different professional communities.

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This book seeks to investigate ‘platform power’ in the multi-platform era and unravels the evolution of power structures in the TV industry as a result of platformisation. Multiple TV platforms and modes of distribution are competing–not necessarily in a zero-sum game–to control the market. In the volume, the contributors work to extend established ‘platform theory’ to the TV industry, which has become increasingly organised as a platform economy. The book helps to understand how platform power arises in the industry, how it destabilises international relations, and how it is used in the global media value chain. Platform Power and Policy in Transforming Television Markets contributes to the growing field of media industry studies, and draws on scholarly work in communication, political economy and public policy whilst providing a deeper insight into the transformation of the TV industry from an economic, political and consumer level. Avoiding a merely legal analysis from a technology-driven perspective, the book provides a critical analysis of the dominant modes of power within the evolving structures of the global TV value chain.

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This book offers a broad and global level description of the current status of wastewater use in agriculture and then brings the readers to various places in the MENA Region and Europe to explain how some countries and regions have addressed the challenges during implementation. On a global scale, over 20 million hectares of agricultural land are irrigated using wastewater. This is one good, and perhaps the most prominent, example of the safe use potential of wastewater. Water scarcity and the cost of energy and fertilisers are among the main factors driving millions of farmers and other entrepreneurs to make use of wastewater. In order to address the technical, institutional, and policy challenges of safe water reuse, developing countries and countries in transition need clear institutional arrangements and more skilled human resources, with a sound understanding of the opportunities and potential risks of wastewater use. Stakeholders in wastewater irrigation who need to implement from scratch or improve current conditions, find it difficult to gather the necessary information on practical implementation aspects. The main objective of this book is to bridge that gap.

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This book is an analysis of the specificities of public film funding on an international scale. It shows how public funding schemes add value to film-making and other audio-visual productions and provides a comprehensive analysis of today’s global challenges in the film industry such as industry change, digital transformation, and shifting audience tastes. Based on insights from fields such as cultural economics, media economics, media management and media governance studies, the authors illustrate how public spending shapes the financial fitness of national and international film industries. This highly informative book will help both scholars and practitioners in the film industry to understand the complexity of issues and the requirements necessary to preserve the social benefits of film as an important cultural good.

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Luigi L. Pasinetti (born 1930) is arguably the most influential of the second generation of the Cambridge Keynesian School of Economics, both because of his achievements and his early involvement with the direct pupils of John Maynard Keynes. This comprehensive intellectual biography traces his research from his early groundbreaking contribution in the field of structural economic dynamics to the ‘Pasinetti Theorem’. With scientific outputs spanning more than six decades (1955–2017), Baranzini and Mirante analyse the impact of his research work and roles at Cambridge, the Catholic University of Milan and at the new University of Lugano. Pasinetti’s whole scientific life has been driven by the desire to provide new frameworks to explain the mechanisms of modern economic systems, and this book assesses how far this has been achieved.

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This book addresses major issues facing postal and delivery services throughout the world. Worldwide, there is currently a considerable amount of interest in postal and delivery economics. The industry is in a state of near crisis and drastic change is needed. The European Commission and member States are still wrestling with the problem of how to implement entry liberalization into postal markets, how to address digital competition, and how to maintain the universal service obligation (USO). The Postal Accountability and Enhancement Act of 2006 in the U.S. has perhaps created and exacerbated the problems faced by USPS. Post Offices (POs) have been slow to address the threat of electronic competition. On the other hand, e-commerce presents opportunities for POs to expand their presence in parcel delivery and perhaps help finance or redefine the USO. A major aim of this book is to address strategies POs can use to reinvent themselves for the digital age.This book compiles original essays by prominent researchers in the field, which will be selected and edited from papers presented at the 25th Conference on Postal and Delivery Economics held in Barcelona, Spain, May 24-27, 2017. That conference, and this volume, commemorates the memory of Michael Crew who organized twenty-four prior conferences and co-edited previous conference volumes. This book is a useful tool not only for graduate students and professors, but also for postal administrations, consulting firms, and Federal Government departments.

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This volume sheds new light upon the role of victims in the aftermath of violence. Victims are central actors in transitional justice, the politics of memory and conflict resolution, yet the analysis of their mobilisation and political influence in these processes has been neglected. After introducing and explaining the reasons for this limited interest, the book’s chapters focus on a range of settings and draw on different disciplines to offer insights into the interrelated themes of victimhood – victims, their individual and collective identities, and their role in and impact upon post-conflict societies – and the politics of victimhood – meaning how victimhood is defined, negotiated and contested, both socially and politically. Because it outlines a stimulating research agenda and challenges the view that victims are passive or apolitical, this interdisciplinary volume is a significant contribution to the literature and will be of interest to scholars from disciplines such as law, anthropology, political science, human rights, international studies, and to practitioners.

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This book covers the complete field of pulmonary pathology - neoplastic and non-neoplastic - from Acinic cell tumor in the lung to Wegener`s Granulomatosis. The alphabetically arranged entries, each of which provides a detailed description of a specific pathological disease pattern, allow readers to quickly and easily find the information they need.

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This pioneering edited collection explores the question of how organizations manage the future. Moving away from traditional research which focuses on the past, the editors problematize the future as an inherent but under-examined part of organizing. Arguing that the future acts as both a driver of and a performative result of organizing, the book asks how organizations conceptualize and deal with the future and what processes are in place to handle things to come. With empirical research examining the practices, discourses and concepts that play key roles, organizations and their approaches are scrutinized. A timely compendium of theoretical discussion and practical implications on the relevance of the future, this book is essential reading for those interested in organization, sociology and management studies.

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Designing a habitat for the lunar surface? You will need to know more than structural engineering. There are the effects of meteoroids, radiation, and low gravity. Then there are the psychological and psychosocial aspects of living in close quarters, in a dangerous environment, far away from home. All these must be considered when the habitat is sized, materials specified, and structure designed.This book provides an overview of various concepts for lunar habitats and structural designs and characterizes the lunar environment - the technical and the nontechnical. The designs take into consideration psychological comfort, structural strength against seismic and thermal activity, as well as internal pressurization and 1/6 g. Also discussed are micrometeoroid modeling, risk and redundancy as well as probability and reliability, with an introduction to analytical tools that can be useful in modeling uncertainties.

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This book provides information on a range of issues related to prostate cancer survivorship, including; psychosexual care, health related quality of life, treatment, follow-up care, new psychosexual pathways, and acute and chronic co-morbidities. The book also covers the needs and challenges in survivorship care, the requirements of care, the future of survivorship care, and role of patient conferences. This book aims to give oncologists, urologists, and specialist nurses help in how to manage patients in the prostate cancer survivorship phase. This guidance is based on real life experiences handling prostate cancer survivorship, and is developed further through utilising the views of both health care professionals and patients.

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This comprehensive treatment of multivariable calculus focuses on the numerous tools that MATLAB® brings to the subject, as it presents introductions to geometry, mathematical physics, and kinematics. Covering simple calculations with MATLAB®, relevant plots, integration, and optimization, the numerous problem sets encourage practice with newly learned skills that cultivate the reader’s understanding of the material. Significant examples illustrate each topic, and fundamental physical applications such as Kepler’s Law, electromagnetism, fluid flow, and energy estimation are brought to prominent position. Perfect for use as a supplement to any standard multivariable calculus text, a “mathematical methods in physics or engineering” class, for independent study, or even as the class text in an “honors” multivariable calculus course, this textbook will appeal to mathematics, engineering, and physical science students. MATLAB® is tightly integrated into every portion of this book, and its graphical capabilities are used to present vibrant pictures of curves and surfaces. Readers benefit from the deep connections made between mathematics and science while learning more about the intrinsic geometry of curves and surfaces. With serious yet elementary explanation of various numerical algorithms, this textbook enlivens the teaching of multivariable calculus and mathematical methods courses for scientists and engineers.

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This book provides a basic, initial resource, introducing science and engineering students to the field of optimization. It covers three main areas: mathematical programming, calculus of variations and optimal control, highlighting the ideas and concepts and offering insights into the importance of optimality conditions in each area. It also systematically presents affordable approximation methods. Exercises at various levels have been included to support the learning process.

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This book provides users with cutting edge methods and technologies in the area of big data and visual analytics, as well as an insight to the big data and data analytics research conducted by world-renowned researchers in this field. The authors present comprehensive educational resources on big data and visual analytics covering state-of-the art techniques on data analytics, data and information visualization, and visual analytics. Each chapter covers specific topics related to big data and data analytics as virtual data machine, security of big data, big data applications, high performance computing cluster, and big data implementation techniques. Every chapter includes a description of an unique contribution to the area of big data and visual analytics. This book is a valuable resource for researchers and professionals working in the area of big data, data analytics, and information visualization. Advanced-level students studying computer science will also find this book helpful as a secondary textbook or reference.

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This book addresses a conundrum for the international development community: The law of development cooperation poses major constraints on delivering aid where it is needed most. The existence of a state with an effective government is a basic condition for the transfer of aid, making development cooperation with ‘fragile’ nations particularly challenging. The author explores how international organizations like the World Bank have responded by adopting formal and informal rules to engage specifically with countries with weak or no governments. Von Engelhardt provides a critical analysis of the discourse on fragile states and how it has shaped the policy decision-making of international organizations. By demonstrating how perceptions of fragility can have significant consequences both in practice and in law, the work challenges conventional research that dismisses state fragility as a phenomenon beyond law. It also argues that the legal parameters for effective global policy play a crucial role, and offers a fresh approach to a topic that is central to international security and development.

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This book highlights the increase in thyroid tumors and NET and demonstrates the growing importance of circulating markers in diagnosis as well as treatment and follow-up. Dramatic technical improvements have heightened the clinical impact of well-established, conventional biochemical markers. In addition, more recent genetic and molecular approaches have provided innovative molecular markers. In this context, effective communication between clinicians and laboratory physicians/scientists is essential in allowing all those involved to fully profit from these exciting advances. In this comprehensive, up-to-date book, authors from different laboratory and clinical areas link laboratory and clinical topics. Analytical problems such as interferences, false-negative and false-positive results are discussed in depth, and flow-charts offer insights into identifying and avoiding them. Illustrated clinical cases detail the clinical role and limitations of different tumor markers. Lastly, it explores health technology assessment and economic issues. This is a valuable resource for endocrinologists, oncologists, nuclear medicine physicians, scientists and technologists who want to keep abreast of the latest developments.

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This work explores essential debates on globalization and world-systems analysis. It begins with a review of theoretical insights from world-systems analysis and explains the evolution of its terminology. The book subsequently seeks to answer several important questions: When did globalization begin and what insights into contemporary globalization may be gained from older forms? How does globalization differ in different places, and how can different instances of globalization be compared? Who is affected by globalization, how are they affected, and how do these effects vary, if at all, over time and space?As world-systems analysis and studies of globalization require interdisciplinary expertise, the contributing authors draw on many fields, including anthropology, economics, geography, philosophy, political science, sociology, and world history. The book’s overall goal is to facilitate the dialogue between approaches that, at times, seem to “talk at cross-purposes,” and to extend an invitation to scholars from many different areas to explore globalization.

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Written for those who want to develop their knowledge of requirements engineering process, whether practitioners or students.Using the latest research and driven by practical experience from industry, Requirements Engineering gives useful hints to practitioners on how to write and structure requirements. It explains the importance of Systems Engineering and the creation of effective solutions to problems. It describes the underlying representations used in system modeling and introduces the UML2, and considers the relationship between requirements and modeling. Covering a generic multi-layer requirements process, the book discusses the key elements of effective requirements management. The latest version of DOORS (Version 7) - a software tool which serves as an enabler of a requirements management process - is also introduced to the reader here.Additional material and links are available at: http://www.requirementsengineering.info

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This handbook offers a critical assessment of the African agenda for conflict prevention, peacemaking, peacekeeping, and peacebuilding; the challenges and opportunities facing Africa’s regional organisations in their efforts towards building sustainable peace on the continent; and the role of external actors, including the United Nations, Britain, France, and South Asian troop-contributing countries. In so doing, it revisits the late Ali Mazrui’s concept of Pax Africana, calling on Africans to take responsibility for peace and security on their own continent. The creation of the African Union, in 2002, was an important step towards realising this ambition, and has led to the development of a new continental architecture for more robust conflict management. But, as the volume’s authors show, the quest for Pax Africana faces challenges. Combining thematic analyses and case studies, this book will be of interest to both scholars and policymakers working on peace, security, and governance issues in Africa.

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This book shares unique perspectives on the successful global evolution and future ambitions of Chinese consumer companies. It presents an unprecedented collection of one-on-one interviews with some of the most influential leaders in China, whose companies offer diverse products and services. Further, the book offers future business leaders encouragement and guidance on how to ride the consumer wave in China. It also investigates some of the foremost current trends, revealing the best opportunities for companies to succeed on the Chinese market. Written by a successful business leader, this book is a timely must-read for anyone seeking to understand Chinese consumers, the Chinese market and what makes Chinese entrepreneurs tick – helping them learn how to do business “Made for China”.

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This book summarizes the results of Design Thinking Research Program at Stanford University in Palo Alto, California, USA and the Hasso Plattner Institute in Potsdam, Germany. Offering readers a closer look at design thinking, its innovation processes and methods, it covers topics ranging from how to design ideas, methods and technologies, to creativity experiments and creative collaboration in the real world, and the interplay between designers and engineers. But the topics go beyond this in their detailed exploration of design thinking and its use in IT systems engineering fields, and even from a management perspective. The authors show how these methods and strategies actually work in companies, and introduce new technologies and their functions. Furthermore, readers learn how special-purpose design thinking can be used to solve thorny problems in complex fields. Thinking and devising innovations are fundamentally and inherently human activities – so is design thinking. Accordingly, design thinking is not merely the result of special courses nor of being gifted or trained: it’s a way of dealing with our environment and improving techniques, technologies and life. This edition offers a historic perspective on the theoretical foundations of design thinking. Within the four topic areas, various frameworks, methodologies, mindsets, systems and tools are explored and further developed. The first topic area focuses on team interaction, while the second part addresses tools and techniques for productive collaboration. The third section explores new approaches to teaching and enabling creative skills and lastly the book examines how design thinking is put into practice. All in all, the contributions shed light and provide deeper insights into how to support the collaboration of design teams in order to systematically and successfully develop innovations and design progressive solutions for tomorrow.

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This book analyses the conflicts that emerged from the Brazilian labour movement’s active participation in a rapidly changing political environment, particularly in the context of the coming to power of a party with strong roots in the labour movement. While the close relations with the Workers' Party (PT) have shaped the labour movement’s political agenda, its trajectory cannot be understood solely with reference to that party’s electoral fortunes. Through a study of the political trajectory of the Brazilian labour movement over the last three decades, the author explores the conditions under which the labour movement has developed militant and moderate strategies.

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Providing a comprehensive overview of the current orthopedic uses of intramedullary devices, this practical, well-illustrated guide opens with a review of the history of limb lengthening from the early external fixator up to Ilizarov’s monumental discoveries, with a summary of the biology of new bone formation in a widening distraction gap. This is followed by post-Ilizarov developments with external fixators designed to ease application and increase patient tolerance of such devices, as well as a discussion of the intramedullary lengthening devices from the earliest mechanical distractors to the most modern implants, detailing the surgical principles, pre-operative planning and specific operative techniques for each. Concluding chapters focus on preventing and dealing with complications from the surgery and day-to-day post-operative management. A unique feature of the book is a cross-section atlas of the upper and lower limbs that will assist surgeons to avoid impaling neurovascular structures during the minimally invasive portions of operative insertion of the implants.Intramedullary Limb Lengthening: Principles and Practice is an ideal, on-the-spot resource for orthopedic surgeons, residents and trainees treating pediatric and adult limb deformities and length deficiencies, as well as physical therapists and other health care providers who manage such patients post-operatively.

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This book is a useful reference in the field of urbanism. It explains how the contemporary city and landscape have been shaped by certain twentieth century visions that have carried over into the twenty-first century. Aimed at both students and professionals, this collection of essays on diverse subjects and cases does not attempt to establish universal interpretations; it rather highlights some outstanding episodes that help us understand why the planning culture has given way to other forms of urbanism, from urban design to strategic urbanism or landscape urbanism. Compared with global interpretations of urbanism based on socioeconomic history or architectural historiography, Urban Visions. From Planning Culture to Landscape Urbanism, aims to present the discipline couched in international contemporary debate and adopt a historic and comparative perspective. The book’s contents pertain equally to other related disciplines, such as architecture, urban history, urban design, landscape architecture and geography.Foreword by Rafael Moneo.

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A concise guide for ophthalmologists detailing tuberculosis, which can cause disease in multiple organs throughout the body, including the eye. Tuberculosis is an infection caused by mycobacterium tuberculosis, which can cause disease in multiple organs throughout the body, including the eye. This can also affect any part of the eye (intraocular, superficial, or surrounding the eye), with or without systemic involvement and Ocular Tuberculosis is a text devoted to in-depth coverage of this topic.Written and edited by international leaders in the field, discussing detailed and practical information on everything from clinical features, ocular imaging studies, and pathology, to investigations, treatment, and surgical management of this disease, Ocular Tuberculosis is a truly comprehensive text.

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This book examines how digital technology is being used to assist the artists and designers. The computer is able to store data and reproduce designs, thus facilitating the speed-up of the iterative process towards a final design which meets the objectives of the designer and the requirements of the user. Collaborative design enables the sharing of information across digital networks to produce designed objects in virtual spaces. Augmented and virtual reality techniques can be used to preview designs before they are finalized and implemented. Art and design have shaped the values, social structures, communications, and the culture of communities and civilisations. The direct involvement of artists and designers with their creative works has left a legacy enabling subsequent generations to understand more about their skills, their motivations, and their relationship to the wider world, and to see it from a variety of perspectives. This in turn causes the viewers of their works to reflect upon their meaning for today and the lasting value and implications of what has been created. Art installations are harnessing modern technology to process information and to display it. Such environments have also proved useful in engaging users and visitors with real-time images and interactive art.

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This book introduces readers to additive technology and its application in different business sectors. It explores the fundamental impact additive has on technology, particularly on operations, innovation, supply chains, the environment and customer relations. Subsequently, on the basis of a broad survey of the best technology adopters, it offers advice on how to enhance business value by implementing the technology in different industrial and commercial environments.Additive manufacturing (AM) is a new area of manufacturing that has already brought about phenomenal changes to industry and business models. It affects nearly all aspects of the managerial and organizational thinking that was applied to conventional manufacturing. Currently, the technology is being adopted in manufacturing areas that involve high-value products with complex geometries, and small to medium production volumes. It boosts the productivity of new product development processes by slashing costs, reducing time and promoting creativity and innovativeness. Further, it shrinks supply chains by bringing firms closer to their customers. This unique book offers abundant empirical and practical evidence confirming the value of this new technology.

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This book provides details and collective information on working principle, process mechanism, salient features, and unique applications of various advanced manufacturing techniques and processes belong. The book is divided in three sessions covering modern machining methods, advanced repair and joining techniques and, finally, sustainable manufacturing. The latest trends and research aspects of those fields are highlighted.

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This textbook on computational statistics presents tools and concepts of univariate and multivariate statistical data analysis with a strong focus on applications and implementations in the statistical software R. It covers mathematical, statistical as well as programming problems in computational statistics and contains a wide variety of practical examples. In addition to the numerous R sniplets presented in the text, all computer programs (quantlets) and data sets to the book are available on GitHub and referred to in the book. This enables the reader to fully reproduce as well as modify and adjust all examples to their needs.The book is intended for advanced undergraduate and first-year graduate students as well as for data analysts new to the job who would like a tour of the various statistical tools in a data analysis workshop. The experienced reader with a good knowledge of statistics and programming might skip some sections on univariate models and enjoy the various mathematical roots of multivariate techniques.The Quantlet platform quantlet.de, quantlet.com, quantlet.org is an integrated QuantNet environment consisting of different types of statistics-related documents and program codes. Its goal is to promote reproducibility and offer a platform for sharing validated knowledge native to the social web. QuantNet and the corresponding Data-Driven Documents-based visualization allows readers to reproduce the tables, pictures and calculations inside this Springer book.

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This edited volume discusses the theoretical, practical and methodological issues surrounding changes in journalism in the digital era. The chapters explore how technological innovations have transformed journalism and how an international comparative perspective can contribute to our understanding of the topic. Journalism is examined within Anglo-American and European contexts as well as in Asia and Africa, and comparative approaches and methods for journalism studies in the digital age are evaluated. In so doing, the book offers a thorough investigation of changes in journalistic norms, practices and genres in addition to providing an international and comparative perspective for understanding these changes and what they mean to journalism. Written by both leading scholars and media practitioners in the field, the articles in this collection are based on theoretical frameworks and empirical data, drawn from content analysis of newspaper and online coverage, in-depth interviews with news practitioners, observation on the websites of news organisations and analysis of journalists on Twitter. The result is a cohesive compilation that offers the reader an up-to-date and comprehensive understanding of digital developments in journalism and comparative journalism studies.

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