Search results for ""redline""

Sleep has recently been recognized as a critical determinant of energy balance regulating, restoration and repair of many of the physiologic and psychologic processes involved in modulating energy intake and utilization. In addition to having an impact on obesity, sleep abnormalities, both quantitative and qualitative, have now been shown to have significant effects on obesity associated comorbidities, including metabolic syndrome, premalignant lesions and cancer. Sleep problems and fatigue also constitute a significant challenge for the ever expanding group of cancer survivors. Moreover, circadian misalignment, such as that experienced by "shift workers" has been shown to be associated with an increased incidence of several malignancies including, breast, colorectal and prostate cancer, consistent with the increasing recognition of the role of clock genes in the metabolic processes. Of increasing concern is the accelerating incidence of sleep disorders in childhood, their association with childhood obesity and associated abnormalities of circulating cytokines, adipokines and metabolic factors, many of which are implicated as etiologic mediators of the connection between obesity and cancer.Extensive studies have now been initiated to investigate the mechanisms by which disturbances in sleep duration, sleep continuity and sleep related breathing affect circadian rhythm, central and peripheral tissue oxygenation and metabolism, quality and quantity of dietary intake and circulating inflammatory cytokines and regulatory hormones. This volume aims to present the latest research on sleep, sleep disturbance and its correlation to obesity and cancer.

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Harry Vos, a retired man and part-time private investigator who lives near Antwerp, is torn between the pleasures of retirement and the attractions of involvement in challenging investigations. A big family man, he nevertheless finds it difficult to turn down opportunities to test his investigative skills. When an old friend phones and tells him about the possibility of becoming an heir hunter, he jumps at the chance. Kurt Baumer, from St Vith, in the German speaking area of Belgium, died with no known heirs. Progress on finding an heir is slow, but assisted by his daughter Josina, Harry gradually allows himself to get drawn into a wider investigation, which uncovers Kurt’s questionable dealings in African artefacts. When the deceased is found to have been in possession of some diamonds, alarm bells really start to ring. Further enquiries take Harry into the world of art smuggling. And as an old adversary from the Redline case resurfaces in search of revenge, the stakes for Harry are higher than ever.

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Marketed as the “fastest metal cars in the world,” Hot Wheels*r revolutionized the die-cast toy car market. Collectors throughout the world recognize the Hot Wheels*r brand. The models produced between 1968 and 1972 represent the vintage years for this line of toy vehicles. The bright “Spectraflame*r” paint colors and “redline” tires, unique to Hot Wheels vehicles, identify these models. These original models still drive the collecting hobby today. The 221 wonderful color photographs provide a complete visual guide for collectors. The 118 unique castings produced during this four-year period are explained in detail and a complete variation and price guide is provided to expand knowledge and interest in collecting Hot Wheels. Also included is coverage of the Gran Toros*t cars, launched soon after Mattel bought the Italian company Mebetoys. Introduced in 1970, the line was continued until 1973, though the name continued to 1980/81. This new book is a welcomed addition to Hot Wheels literature by one of the world’s foremost experts in the field.

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