Search results for ""elsevier science""

Biomechanics of the Female Reproductive System: Breast and Pelvic Organs: From Models to Patients synthesizes complementary advances in women’s reproductive biomechanics, medical imaging analysis, patient-specific characterization, and computational finite element models. The book discusses the biomechanical aspects related to the breast and female pelvic floor system at each step of development. The table of contents also covers certain events and diseases, including cancers, delivery, aging, breast, hysterectomy or prolapse surgery. It presents the main biomechanical experimental results obtained and models developed this last decade to highlight the importance of accounting for patient-specific history and aging characteristics to consider damage growth effect and impact. As part of Elsevier’s Biomechanics of Living Organs series, this book provides an opportunity for students, researchers, clinicians and engineers to study the main topics related to the biomechanics of the women’s reproductive system in a single book written by a global base of experts.

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Diet and Nutrition in Neurological Disorders offers readers a comprehensive reference on the effect of dietary regimes in a wide variety of neurological diseases. With coverage of different types of diets, including Mediterranean or DASH, this broad coverage allows readers to learn about diets and their affect on specific disorders which may well be relevant to other conditions. This includes diseases such as Alzheimer’s, Parkinson’s, ALS, MS and severe neurological conditions such as brain injury, stroke, headache and migraine. This volume provides a platform for research on new dietary regimes and on future investigations of diet and nutrition.

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Pregnancy, childbirth, childhood, adolescence, and aging can be beset with adverse changes in psychobiology and behavior. Handbook of Lifespan Cognitive Behavioral Therapy: Childhood, Adolescence, Pregnancy, Adulthood, and Aging will better readers’ understanding of a variety of conditions and the applicability of CBT therapy as a treatment. Featuring chapters on postnatal anxiety and depression, insomnia, and dysmorphia, the book discusses in detail the use of cognitive behavioral therapies in the treatment of these issues affecting individuals at the start and end of their lives. With expert authors from the clinical field, the book has applicability for behavioral scientists, psychologists, cognitive and behavioral neuroscientists, and anyone working to better understand and treat using cognitive behavioral therapies.

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Embedded Systems: ARM Programming and Optimization, Second Edition combines an exploration of the ARM architecture with an examination of the facilities offered by the Linux operating system to explain how various features of program design can influence processor performance. The book demonstrates methods by which a programmer can optimize program code in a way that does not impact its behavior but instead improves its performance. Several applications, including image transformations, fractal generation, image convolution, computer vision tasks, and now machine learning are used to describe and demonstrate these methods. From this, the reader will gain insight into computer architecture and application design, as well as practical knowledge in embedded software design for modern embedded systems. The second edition has been expanded to include more topics of interest to upper level undergraduate courses in embedded systems.

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Computer Networks: A Systems Approach, Sixth Edition, explores the key principles of computer networking, using real world examples from network and protocol design. Using the Internet as the primary example, this best-selling classic textbook explains various protocols and networking technologies. The systems-oriented approach encourages students to think about how individual network components fit into a larger, complex system of interactions. This sixth edition contains completely updated content with expanded coverage of the topics of utmost importance to networking professionals and students, as provided by numerous contributors via a unique open source model developed jointly by the authors and publisher. Hallmark features of the book are retained, including chapter problem statements, which introduce issues to be examined; shaded sidebars that elaborate on a topic or introduce a related advanced topic; What’s Next? discussions that deal with emerging issues in research, the commercial world, or society; and exercises. This book is intended primarily for graduate or upper-division undergraduate classes in computer networking. It will also be useful for industry professionals retraining for network-related assignments, as well as for network practitioners seeking to understand the workings of network protocols and the big picture of networking.

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Engineering a Compiler, Third Edition covers the latest developments in compiler technology, with new chapters focusing on semantic elaboration (the problems that arise in generating code from the ad-hoc syntax-directed translation schemes in a generated parser), on runtime support for naming and addressability, and on code shape for expressions, assignments and control-structures. Leading educators and researchers, Keith Cooper and Linda Torczon, have revised this popular text with a fresh approach to learning important techniques for constructing a modern compiler, combining basic principles with pragmatic insights from their own experience building state-of-the-art compilers.

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Reservoir Engineering Handbook, Fifth Edition, equips engineers and students with the knowledge required to continue maximizing reservoir assets, especially as more reservoirs become complex, multi-layered, and unconventional in their extraction methods. Building on the solid reputation of the previous edition, this new volume presents critical concepts, such as fluid flow, rock properties, water and gas coning, and relative permeability in a straightforward manner. Water influx calculations, lab tests of reservoir fluids, oil and gas performance calculations, and other essential tools of the trade are also introduced, reflecting on today’s operations. New to this edition is an additional chapter devoted to enhanced oil recovery techniques, including WAG. Critical new advances in areas such as well performance, waterflooding, and an analysis of decline and type curves are also addressed, along with more information on the growing extraction from unconventional reservoirs. Practical and critical for new practicing reservoir engineers and petroleum engineering students, this book remains the authoritative handbook on modern reservoir engineering and its theory and practice.

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An Introduction to Parallel Programming, Second Edition presents a tried-and-true tutorial approach that shows students how to develop effective parallel programs with MPI, Pthreads and OpenMP. As the first undergraduate text to directly address compiling and running parallel programs on multi-core and cluster architecture, this second edition carries forward its clear explanations for designing, debugging and evaluating the performance of distributed and shared-memory programs while adding coverage of accelerators via new content on GPU programming and heterogeneous programming. New and improved user-friendly exercises teach students how to compile, run and modify example programs.

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Analog circuit and system design today is more essential than ever before. With the growth of digital systems, wireless communications, complex industrial and automotive systems, designers are being challenged to develop sophisticated analog solutions. This comprehensive source book of circuit design solutions aids engineers with elegant and practical design techniques that focus on common analog challenges. The book’s in-depth application examples provide insight into circuit design and application solutions that you can apply in today’s demanding designs.

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Combinational Therapy in Triple Negative Breast Cancer discusses TNBC at the molecular level from a holistic approach, focusing on combinational strategies targeting various pathways involved in this specific cancer type. Using a monotherapy for the treatment of cancer, especially high-grade tumors like TNBC, is mostly worthless due to the inherent genetic instability of tumor cells to develop intrinsic and acquired resistance. Combination therapy presents more, or at least the same, effectiveness with lower doses of every single agent and decreases the likelihood of chemoresistance, making it essential to understand for multiple therapy options. The book is a valuable resource for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in the potential of combinational therapies to treat triple negative breast cancer.

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Novel Therapeutic Approaches Targeting Oxidative Stress investigates the role of oxidative stress in disease and explores the latest methods and approaches to targeting oxidative stress for treatment and diagnosis. The book begins with an introduction to oxidative stress and its significance. Subsequent sections cover biochemical methods for detecting free radicals and novel therapeutic approaches for targeting oxidative stress in a number of different diseases. This includes age-related illnesses, neuropsychiatric disorders such as schizophrenia and bipolar disorder, and neurodegenerative diseases like Alzheimer’s and Parkinson’s disease. Novel approaches for targeting oxidative stress in cancer and cardiovascular diseases are also explored. The book then moves on to discuss advances in drug delivery systems and detecting oxidative stress biomarkers using biosensors. It concludes with case studies that illustrate the targeting of oxidative stress and future perspectives.

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System Assurances: Modeling and Management updates on system assurance and performance methods using advanced analytics and understanding of software reliability growth modeling from today’s debugging team’s point-of-view, along with information on preventive and predictive maintenance and the efficient use of testing resources. The book presents the rapidly growing application areas of systems and software modeling, including intelligent synthetic characters, human-machine interface, menu generators, user acceptance analysis, picture archiving and software systems. Students, research scholars, academicians, scientists and industry practitioners will benefit from the book as it provides better insights into modern related global trends, issues and practices.

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Optical Fiber Sensors for the Next Generation of Rehabilitation Robotics presents development concepts and applications of optical fiber sensors made of compliant materials in rehabilitation robotics. The book provides methods for the instrumentation of novel compliant devices. It presents the development, characterization and application of optical fiber sensors in robotics, ranging from conventional robots with rigid structures to novel wearable systems with soft structures, including smart textiles and intelligent structures for healthcare. Readers can look to this book for help in designing robotic structures for different applications, including problem-solving tactics in soft robotics. This book will be a great resource for mechanical, electrical and electronics engineers and photonics and optical sensing engineers.

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Simulation, Sixth Edition continues to introduce aspiring and practicing actuaries, engineers, computer scientists and others to the practical aspects of constructing computerized simulation studies to analyze and interpret real phenomena. Readers will learn to apply the results of these analyses to problems in a wide variety of fields to obtain effective, accurate solutions and make predictions. By explaining how a computer can be used to generate random numbers and how to use these random numbers to generate the behavior of a stochastic model over time, this book presents the statistics needed to analyze simulated data and validate simulation models.

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Measuring the User Experience: Collecting, Analyzing, and Presenting UX Metrics, Third Edition provides the quantitative analysis training that students and professionals need. This book presents an update on the first resource that focused on how to quantify user experience. Now in its third edition, the authors have expanded on the area of behavioral and physiological metrics, splitting that chapter into sections that cover eye-tracking and measuring emotion. The book also contains new research and updated examples, several new case studies, and new examples using the most recent version of Excel.

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Analyzing Social Media Networks with NodeXL: Insights from a Connected World, Second Edition, provides readers with a thorough, practical and updated guide to NodeXL, the open-source social network analysis (SNA) plug-in for use with Excel. The book analyzes social media, provides a NodeXL tutorial, and presents network analysis case studies, all of which are revised to reflect the latest developments. Sections cover history and concepts, mapping and modeling, the detailed operation of NodeXL, and case studies, including e-mail, Twitter, Facebook, Flickr and YouTube. In addition, there are descriptions of each system and types of analysis for identifying people, documents, groups and events. This book is perfect for use as a course text in social network analysis or as a guide for practicing NodeXL users.

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This volume collects together the presentations at the Eighth International Conference on Foundations of Computer-Aided Process Design, FOCAPD-2014, an event that brings together researchers, educators, and practitioners to identify new challenges and opportunities for process and product design. The chemical industry is currently entering a new phase of rapid evolution. The availability of low-cost feedstocks from natural gas is causing renewed investment in basic chemicals in the OECD, while societal pressures for sustainability and energy security continue to be key drivers in technology development and product selection. This dynamic environment creates opportunities to launch new products and processes and to demonstrate new methodologies for innovation, synthesis and design. FOCAPD-2014 fosters constructive interaction among thought leaders from academia, industry, and government and provides a showcase for the latest research in product and process design.

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MARGO - Multiproxy Approach for the Reconstruction of the Glacial Ocean surface summarizes the results of the MARGO international working group, with the aim to develop an updated and harmonised reconstruction of sea surface temperatures and sea-ice extent of the Last Glacial Maximum oceans. The MARGO approach differs from previous efforts by developing and consistently applying measures of various aspects of reconstruction reliability, and by combining faunal and geochemical proxies. In 14 papers, the volume provides a comprehensive review of earlier work and a series of new, proxy-specific reconstructions based on census counts of planktonic foraminifera, diatoms, radiolaria and dinoflagellate cysts as well as on Mg/Ca measurements in planktonic foraminifera. The approach of harmonising the calibration and application of different proxies is described in detail, various paleothermometry techniques and their results are compared and the challenge of treating sparsely sampled data as the basis for ocean circulation models is addressed. The use of stable oxygen isotope composition of foraminiferal shells as a proxy for past sea water composition is comprehensively reassessed, and a new approach to the transfer function paleothermometer is presented. This volume represents a landmark contribution to the understanding of ice-age oceanography as well as the proxies used to reconstruct past ocean states. The results will form the basis for forcing and validation of ocean circulation models.

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High-Rise Security and Fire Life Safety, 3e, is a comprehensive reference for managing security and fire life safety operations within high-rise buildings. It spells out the unique characteristics of skyscrapers from a security and fire life safety perspective, details the type of security and life safety systems commonly found in them, outlines how to conduct risk assessments, and explains security policies and procedures designed to protect life and property. Craighead also provides guidelines for managing security and life safety functions, including the development of response plans for building emergencies. This latest edition clearly separates out the different types of skyscrapers, from office buildings to hotels to condominiums to mixed-use buildings, and explains how different patterns of use and types of tenancy impact building security and life safety.

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Unlike books currently on the market, this book attempts to satisfy two goals: combine circuits and electronics into a single, unified treatment, and establish a strong connection with the contemporary world of digital systems. It will introduce a new way of looking not only at the treatment of circuits, but also at the treatment of introductory coursework in engineering in general. Using the concept of ''abstraction,'' the book attempts to form a bridge between the world of physics and the world of large computer systems. In particular, it attempts to unify electrical engineering and computer science as the art of creating and exploiting successive abstractions to manage the complexity of building useful electrical systems. Computer systems are simply one type of electrical systems.

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The fourth edition of Ludwig’s Applied Process Design for Chemical and Petrochemical Plants, Volume Three is a core reference for chemical, plant, and process engineers and provides an unrivalled reference on methods, process fundamentals, and supporting design data. New to this edition are expanded chapters on heat transfer plus additional chapters focused on the design of shell and tube heat exchangers, double pipe heat exchangers and air coolers. Heat tracer requirements for pipelines and heat loss from insulated pipelines are covered in this new edition, along with batch heating and cooling of process fluids, process integration, and industrial reactors. The book also looks at the troubleshooting of process equipment and corrosion and metallurgy.

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When this innovative textbook first appeared in 1984 it rapidly became a great success throughout the world and has already been translated into several European and Asian languages. Now the authors have completely revised and updated the text, including more than 2000 new literature references to work published since the first edition. No page has been left unaltered but the novel features which proved so attractive have been retained. The book presents a balanced, coherent and comprehensive account of the chemistry of the elements for both undergraduate and postgraduate students. This crucial central area of chemistry is full of ingenious experiments, intriguing compounds and exciting new discoveries. The authors specifically avoid the term `inorganic chemistry' since this evokes an outmoded view of chemistry which is no longer appropriate in the final decade of the 20th century. Accordingly, the book covers not only the 'inorganic' chemistry of the elements, but also analytical, theoretical, industrial, organometallic, bio-inorganic and other cognate areas of chemistry. The authors have broken with recent tradition in the teaching of their subject and adopted a new and highly successful approach based on descriptive chemistry. The chemistry of the elements is still discussed within the context of an underlying theoretical framework, giving cohesion and structure to the text, but at all times the chemical facts are emphasized. Students are invited to enter the exciting world of chemical phenomena with a sound knowledge and understanding of the subject, to approach experimentation with an open mind, and to assess observations reliably. This is a book that students will not only value during their formal education, but will keep and refer to throughout their careers as chemists.

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The Cerebellum: Disorders and Treatment, Volume 155 updates readers on the latest and clinically relevant advances in the study of cerebellar diseases in children and adults. It is organized into sections detailing: (1) Disorders (starting from the fetal cerebellum, to adult cerebellum) encountered during daily practice, and (2) Therapy (including insights into innovative drug and rehabilitative approaches). The book's innovative structure discusses cerebellar disorders in children and adults as a continuum, with its companion volume, The Cerebellum: From Embryology to Diagnostic Investigations detailing embryology, anatomy, function and diagnostic investigations and neuroimaging, including conventional sequences, diffusion tensor imaging, functional MRI, and connectivity studies.

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Handbook of Commercial Policy explores three main topics that permeate the study of commercial policy. The first section presents a broad set of basic empirical facts regarding the pattern and evolution of commercial policy, with the second section investigating the crosscutting legal issues relating to the purpose and design of agreements. Final sections cover key issues of commercial policy in the modern global economy. Every chapter in the book provides coverage from the perspectives of multilateral, and where appropriate, preferential trade agreements. While most other volumes are policy-oriented, this comprehensive guide explores the ways that intellectual thinking and rigor organize research, further making frontier-level synthesis and current theoretical, and empirical, research accessible to all.

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Thermoregulation, Part I: From Basic Neuroscience to Clinical Neurology, Volume 154, not only reviews how body temperature regulation changes in neurological diseases, but also how this aspect affects the course and outcomes of each disease. Other sections of the volume review three therapeutic approaches that are aimed at manipulating body temperature, including induced hypothermia, induced hyperthermia and antipyretic therapy. The book is comprised of nine sections across two volumes, five dealing with the basic aspects of body temperature regulation and four dealing with the clinical aspects. Basic sections cover the Thermoregulation system, Thermoreceptors, Thermoeffectors, Neural pathways, and Thermoregulation as a homeostatic function. In addition, the book covers the physiology and neuroanatomy of the thermoregulation system and provides descriptions of how the regulation of body temperature intervenes with other physiological functions (such as sleep, osmoregulation, and immunity), stress, exercise and aging. Basic sections serve as an introduction to the four clinical sections: Body Temperature, Clinical Significance, Abnormal Body Temperature, Thermoregulation in Neurological Disease and Therapeutic Interventions.

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Handbook of the Economics of Population Aging, Volume 1B provides the economic literature on aging and associated subjects, presenting comprehensive portraits of both social and theoretical issues. As the second of two volumes in this series on the economics of population aging, it continues the discussion, delving deeper into topics such as the labor market and human resource issues, gerontology, history, and the sociological and political ramifications of this fascinating topic whose inception dates back to the late 1970’s. This volume includes literature that has appeared in general economics journals, in various field journals in economics, especially, but not exclusively, those covering labor market and human resource issues, information from interdisciplinary social science and life science journals, and data presented in papers by economists published in journals associated with gerontology, history, sociology, political science, and demography, amongst others.

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Handbook of the Economics of Population Aging, Volume 1A, provides the economic literature on aging and associated subjects, including social insurance and healthcare costs. This text explores the economic literature on aging and associated subjects, including social insurance, health care costs, the interests of policymakers, and the role of academics. As the first of two volumes, users will find it a great resource on the topics associated with the economics of aging. Together with its companion, volume 1B, this work includes literature that has appeared in general economics journals, in various field journals in economics, especially, but not exclusively, those covering labor market and human resource issues, information from interdisciplinary social science and life science journals, and data presented in papers by economists published in journals associated with gerontology, history, sociology, political science, and demography, amongst others.

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The Stereotaxic Brain Atlas of the Egyptian Fruit Bat provides the first stereotaxic atlas of the brain of the Egyptian fruit bat (Rousettus aegyptiacus), an emerging model in neuroscience. This atlas contains coronal brain sections stained with cresyl violet (Nissl), AChE, and Parvalbumin – all stereotaxically calibrated. It will serve the needs of any neuroscientist who wishes to work with these bats – allowing to precisely target specific brain areas for electrophysiology, optogenetics, pharmacology, and lesioning. More broadly, this atlas will be useful to all neuroscientists working with bats, as it delineates many brain regions that were not delineated so far in any bat species. Finally, this atlas will provide a useful resource for researchers interested in comparative neuroanatomy of the mammalian brain.

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Project Finance in Theory and Practice: Designing, Structuring, and Financing Private and Public Projects, Fourth Edition provides essential, core coverage of project finance, offering new insights into Sharia-compliant instruments and a comprehensive overview of the current state of international regulation of banking post financial crisis. This updated edition includes new case studies and topics related to country risk, along with insights from project finance experts who share their specialized knowledge on legal issues and the role of advisors in project finance details. The book will be useful for readers at all levels of education and experience who want to learn how to succeed in project finance.

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Practical Data Analytics for Innovation in Medicine: Building Real Predictive and Prescriptive Models in Personalized Healthcare and Medical Research Using AI, ML, and Related Technologies, Second Edition discusses the needs of healthcare and medicine in the 21st century, explaining how data analytics play an important and revolutionary role. With healthcare effectiveness and economics facing growing challenges, there is a rapidly emerging movement to fortify medical treatment and administration by tapping the predictive power of big data, such as predictive analytics, which can bolster patient care, reduce costs, and deliver greater efficiencies across a wide range of operational functions. Sections bring a historical perspective, highlight the importance of using predictive analytics to help solve health crisis such as the COVID-19 pandemic, provide access to practical step-by-step tutorials and case studies online, and use exercises based on real-world examples of successful predictive and prescriptive tools and systems. The final part of the book focuses on specific technical operations related to quality, cost-effective medical and nursing care delivery and administration brought by practical predictive analytics.

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Signal Processing and Machine Learning Theory, authored by world-leading experts, reviews the principles, methods and techniques of essential and advanced signal processing theory. These theories and tools are the driving engines of many current and emerging research topics and technologies, such as machine learning, autonomous vehicles, the internet of things, future wireless communications, medical imaging, etc.

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Histopathology Atlas of Acute Radiation Syndrome and Delayed Effects in Rhesus Macaques: Kidney, Lung, Heart, Intestine and Mesenteric Lymph Node provides a thoroughly illustrated review of the tissue damage and reparative changes associated with standardized irradiation doses in rhesus macaques. In addition to time-sequenced, routinely stained histologic sections, the book presents results of numerous histochemical, immunohistochemical and chromogenic in-situ stains that provide insights into the pathogenesis of radiation-associated tissue injury and repair. This book is compiled and written by a board-certified veterinary pathologist with more than 40 years of experience in the interpretation of experimentally induced tissue alterations in laboratory animals. This is an important resource for researchers in the field of animal science radiation injury, including radiation oncologists and individuals involved in disaster preparedness related to accidental or deliberate radiation exposure in large populations.

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Neurobiology and Physiology of the Endocannabinoid System offers readers a comprehensive reference on the neurobiology of this system and the use of cannabimimetic compounds to induce neurological changes and confer symptom relief. With sections on both natural and synthetic compounds, the book's broad coverage allows readers to learn about their use with multiple conditions, as well as the working biology of the endocannabinoid system, its receptors and its ligands. This volume provides a platform for research on the effects of this system and its modulation in brain function and neurological dysfunction.

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For the first time, in this atlas nuclear physicians and radiologists cover the entire hybrid nuclear medicine (PET/CT, SPECT/CT and PET/MRI), based on their own case studies. The structure in three volumes represents an user friendly guide for interpreting PET and SPECT in relation to co-registered CT and/or MRI. Three companion volumes with a practical structure in two-page unit offer to the reader a navigational tool, based on anatomical districts, with labeled and explained low-dose multiplanar CT or MRI views merged with PET fusion imaging on the right hand and contrast enhanced CT or MRI on the other side. This new format enables rapid identification of hybrid nuclear medicine findings which are now routine at leading medical centers. Volume 1 is focused on brain and neck PET imaging, with emphasis on PET/MRI; Volume 2 concerns thorax, abdomen and pelvis, with particular attention on lung and liver segmental anatomy and evaluation of peritoneum. Special chapters on heart, lymph nodes and musculoskeletal system, are collected in the Volume 3. Each chapter begins with three-dimensional CT and/or MRI views of the evaluated anatomical region, bringing forward sectional tables. Clinical cases, tricks and pitfalls linked to several PET or SPECT radiopharmaceuticals help to introduce the reader to peculiar molecular pathways and to improve confidence in cross-sectional imaging, that is vital for the accurate diagnosis and treatment of diseases.

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Actuarial Principles: Lifetables and Mortality Models explores the core of actuarial science: the study of mortality and other risks and applications. Including the CT4 and CT5 UK courses, but applicable to a global audience, this work lightly covers the mathematical and theoretical background of the subject to focus on real life practice. It offers a brief history of the field, why actuarial notation has become universal, and how theory can be applied to many situations. Uniquely covering both life contingency risks and survival models, the text provides numerous exercises (and their solutions), along with complete self-contained real-world assignments.

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Vitamins and Minerals in Neurological Disorders offers readers a comprehensive reference addressing their relationship to brain health in a wide variety of neurological diseases. Examining various compounds, this broad coverage allows readers to learn about the role nutrient deficiency plays in the pathology of many conditions, as well as their potential in treatment. The book covers diseases including Alzheimer’s, Parkinson’s, ALS, and MS, along with severe neurological conditions like brain injury, stroke, headache and migraine. This volume provides a platform for research on vitamins, minerals and future investigations of these compounds.

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Fault-Tolerant Systems, Second Edition, is the first book on fault tolerance design utilizing a systems approach to both hardware and software. No other text takes this approach or offers the comprehensive and up-to-date treatment that Koren and Krishna provide. The book comprehensively covers the design of fault-tolerant hardware and software, use of fault-tolerance techniques to improve manufacturing yields, and design and analysis of networks. Incorporating case studies that highlight more than ten different computer systems with fault-tolerance techniques implemented in their design, the book includes critical material on methods to protect against threats to encryption subsystems used for security purposes. The text’s updated content will help students and practitioners in electrical and computer engineering and computer science learn how to design reliable computing systems, and how to analyze fault-tolerant computing systems.

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Data Mining: Practical Machine Learning Tools and Techniques, Fourth Edition, offers a thorough grounding in machine learning concepts, along with practical advice on applying these tools and techniques in real-world data mining situations. This highly anticipated fourth edition of the most acclaimed work on data mining and machine learning teaches readers everything they need to know to get going, from preparing inputs, interpreting outputs, evaluating results, to the algorithmic methods at the heart of successful data mining approaches. Extensive updates reflect the technical changes and modernizations that have taken place in the field since the last edition, including substantial new chapters on probabilistic methods and on deep learning. Accompanying the book is a new version of the popular WEKA machine learning software from the University of Waikato. Authors Witten, Frank, Hall, and Pal include today's techniques coupled with the methods at the leading edge of contemporary research. Please visit the book companion website at https://www.cs.waikato.ac.nz/~ml/weka/book.html. It contains Powerpoint slides for Chapters 1-12. This is a very comprehensive teaching resource, with many PPT slides covering each chapter of the book Online Appendix on the Weka workbench; again a very comprehensive learning aid for the open source software that goes with the book Table of contents, highlighting the many new sections in the 4th edition, along with reviews of the 1st edition, errata, etc.

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The new ARM Edition of Computer Organization and Design features a subset of the ARMv8-A architecture, which is used to present the fundamentals of hardware technologies, assembly language, computer arithmetic, pipelining, memory hierarchies, and I/O. With the post-PC era now upon us, Computer Organization and Design moves forward to explore this generational change with examples, exercises, and material highlighting the emergence of mobile computing and the Cloud. Updated content featuring tablet computers, Cloud infrastructure, and the ARM (mobile computing devices) and x86 (cloud computing) architectures is included. An online companion Web site provides links to a free version of the DS-5 Community Edition (a free professional quality tool chain developed by ARM), as well as additional advanced content for further study, appendices, glossary, references, and recommended reading.

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Chemical Engineering Design: SI Edition is one of the best-known and most widely used textbooks available for students of chemical engineering. The enduring hallmarks of this classic book are its scope and practical emphasis which make it particularly popular with instructors and students who appreciate its relevance and clarity. This new edition provides coverage of the latest aspects of process design, operations, safety, loss prevention, equipment selection, and much more, including updates on plant and equipment costs, regulations and technical standards.

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Statistical Mechanics, Fourth Edition, explores the physical properties of matter based on the dynamic behavior of its microscopic constituents. This valuable textbook introduces the reader to the historical context of the subject before delving deeper into chapters about thermodynamics, ensemble theory, simple gases theory, Ideal Bose and Fermi systems, statistical mechanics of interacting systems, phase transitions, and computer simulations. In the latest revision, the book's authors have updated the content throughout, including new coverage on biophysical applications, updated exercises, and computer simulations. This updated edition will be an indispensable to students and researchers of statistical mechanics, thermodynamics, and physics.

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The Bioarchaeology of Metabolic Bone Disease, Second Edition is a comprehensive source dedicated to better understanding this group of conditions that have significant consequences for health in both past and present communities on a global scale. This edition presents an updated introduction to the biology and metabolism of mineralised tissues that are fundamental to understanding the expression of the metabolic bone diseases in skeletal remains. The extensive advances in understanding of these conditions in both bioarchaeological and biomedical work are brought together for the reader. Dedicated chapters focussing on each disease emphasise the integration of up-to-date clinical background with the biological basis of disease progression to give guidance on identification. New chapters covering anaemia and approaches to recognising the co-occurrence of pathological conditions have been included, reflecting recent advances in research. Boxes highlighting significant issues, use of information from sources such as texts and nonhuman primates, and theoretical approaches are included in the text. Each chapter closes with ‘Core Concepts’ that summarise key information. The final chapter reviews current challenges in bioarchaeology and provides directions for future research. This is a must-have resource for users at all career stages interested in integrating information on the metabolic bone diseases into bioarchaeological projects.

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Advances in Aggregation Induced Emission Materials in Biosensing and Imaging for Biomedical Applications - Part B, Volume 185 presents many aspects of AIE materials that can help future investigators, researchers, students and stakeholders perform research with ease. This volume covers various topics, including tissue and protein fibrils imaging by AIE active molecules, theranostic and photodynamic therapy applications of AIE materials for cancer cell treatment, and AIE active polymers and MOF materials for biological applications. Fluorescence-based monitoring and diagnosis platforms furnish extensive insights into the molecular mechanisms of cellular processes, helping us precisely guide therapeutics.

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Contemporary Medical Biotechnology Research for Human Health discusses a range of currently available solutions required to defeat the ever-increasing human health challenges. The junction between biotechnology and biomedical/health sciences has led to several improvements in patients’ treatment, diagnosis and well-being. The book discusses vital topics ranging from biofilms and UTI, mycobacterial infections, diabetes, aplastic anemia, oral cancer, and possible applications of nanoparticles. In addition, it discusses computer-aided drug design using natural products and new technologies to develop antibiotics. This is a valuable resource for biotechnology and biomedical researchers, bioinformaticians and members of health sciences interested in understanding recent technological developments.

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