Search results for ""royal society of chemistry""

Antimicrobial polymers are materials that prevent microorganism growth and are needed for many everyday applications from food packaging and water treatment to medicine and healthcare. This new book covers different areas of antimicrobial materials based on polymers including chitosan, polymers with ammonium and phosphonium groups, polymer nanofibers, carbon-based polymer Nanocomposites, polymeric and non-polymeric metal complexes, and biomimetic materials. By combining the information of different materials as well as antimicrobial action modes and applications within one source, the book provides a general summary of the field. Polymeric Materials with Antimicrobial Activity starts with a general introduction to antimicrobial polymers and presents the most common types of microorganisms (bacteria, fungi, yeast and algae) along with the main areas of application of antimicrobial polymeric materials. Specific chapters then detail different polymer systems covering the fundamental issues of synthesis, characterization, physico-chemical properties and applications. With contributions from leading scientists the book is suitable for researchers in polymers, chemistry, biology and materials science interested in an overview of antimicrobial polymeric materials as well as the recent advances in their synthesis, properties and applications.

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Conjugated polymers are gaining a lot of interest due to their inherent functional properties and applications in plastic electronics. Their characteristic charge transporting and conducting properties produces features including coloration, photoluminescence, electroluminescence, photoconductivity, and electrochromism. In order to develop new functional polymers, researchers need the background information on the synthesis of the different polymer systems. Conjugated Polymers focuses on the practical preparation of conjugated polymers with each chapter discussing a particular type of conjugated polymer including a general explanation of the polymer, experimental details for synthesis and characterization. Edited by world leading experts in the field of conjugated polymer synthesis, the book serves as a convenient guide for advanced undergraduate level and above.

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Hydrogels are attractive materials for uses in regenerative medicine due to their biocompatibility and high water absorbance and retention properties. Applications are emerging in stem cell niches, biopolymers and synthetic polymers for tissue scaffolding, wound healing and hydrogels for cellular diagnostics and delivery. Hydrogels in Cell-Based Therapies looks at the use of different polymers and other bionanomaterials to fabricate different hydrogel systems and their biomedical applications including enzyme responsive hydrogels and biomaterials, thermally responsive hydrogels, collagen gels and alginates. With complementary expertise in cell biology and soft materials, the Editors provide a comprehensive overview of recent updates in this extremely topical field. This highly interdisciplinary subject will appeal to researchers in cell biology, biochemistry, biomaterials and polymer science and those interested in hydrogel applications.

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As a component of post-genome science, the field of proteomics has assumed great prominence in recent years. Whereas quantitative analyses focussed initially on relative quantification, a greater emphasis is now placed on absolute quantification and consideration of proteome dynamics. Coverage of the topic of quantitative proteomics requires consideration both of the analytical fundamentals of quantitative mass spectrometry and the specific demands of the problem being addressed. Quantitative Proteomics aims to outline the state of the art in mass spectrometry-based quantitative proteomics, describing recent advances and current limitations in the instrumentation used, together with the various methods employed for generating high quality data. Details on both strategies describing how stable isotope labelling can be applied and methods for performing quantitative analysis of proteins in a label-free manner are given. The utility of these strategies to understanding cellular protein dynamics are then exemplified with chapters looking at spatial proteomics, dynamics of protein function as determined by quantifying changes in protein post-translational modification and protein turnover. Finally, a key application of these techniques to biomarker discovery and validation is presented, together with the rapidly developing area of quantitative analysis of protein-based foodstuffs. This exemplary book is essential reading for analytical and biological mass spectrometrists working in proteomics research, as well as those undertaking either fundamental or clinical-based investigations with an interest in understanding protein dynamics and/or biomarker assessment.

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Thiol-X chemistries are already well established techniques, but it is only recently that they have been exploited for the functionalization and synthesis of polymers and other materials. As such, information on these techniques is scattered across the literature and Thiol-X Chemistries in Polymer and Materials Science is the first book to compile work specifically focussing on the application of thiol-based chemistries in materials design and synthesis. The book introduces the various thiol-X chemistries currently available and applications where they have been successfully used, including examples of 'click' processes, in polymerizations, polymer synthesis, and polymer modification. Short 'how to' sections within the chapters also provide general experimental techniques to employ the various chemistries described. Written by leading experts in the field, this book is a comprehensive resource for postgraduates, academics and industrial practitioners interested in polymer and materials applications.

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Due to their impressive performance biological adhesives have inspired the development of superior industrial adhesives. Biological adhesives often provide elegant solutions to engineering and biomedical requirements and are expected to inspire future technological innovations for adhesives for use in hostile conditions. Containing a selection of papers presented at the 1st International Conference on Biological and Biomimetic Adhesives, this book will showcase the latest advances in the chemical and structural characterisation of adhesives, the mechanical testing of adhesives and theory, fabrication and applications of biomimetic adhesives. Following the work of COST Action TD0909, the aim is to gain greater understanding of the mode of action of biological adhesives to allow successful development of improved synthetic counterparts. Appealing to a wide range of researchers in biology, chemistry, physics and engineering, the title provides the background and drive to improve scientific and technological progress in this important area.

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This book aims to provide a comprehensive examination of the field of molecular chaperone inhibition and its application to pharmaceutical research. With several small molecule inhibitors in oncology clinical development, there is clearly intense interest in the chaperones as a molecular target. Filling a significant gap in the market by providing a detailed comparison of discovery programs across the industry, this text will find broad interest among researchers in the field of molecular chaperone pharmaceutical research, oncology research, and medicinal chemistry. Arranged into three main sections the book covers structure and function, small molecule inhibitors and concludes with a section discussing clinical perspectives. With specific chapters covering the discovery of key molecules such as, BIIB028, STA-9090, Serenex Hsp90 inhibitor, NVP-AUY922 and NVP-HSP990, this comprehensive text is an essential treatise for researchers working in academia and industry.

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The concept of a metabolic profile was introduced in 1971, when gas chromatography demonstrated a range of compounds present in human samples. Now termed metabolomics, the field is still emerging, and chromatography remains an essential tool for determining metabolites in a living system. This is the first book to present the chromatographic techniques used in metabolomics in a fundamental way. Sample preparation and quality control are described in detail, and all forms of chromatography applied to metabolomics are included. The editors present guidelines on selecting the most appropriate methodology, making the book an accessible guide to anyone entering the field. Handling data and applications are also described. This is an essential handbook for any laboratory looking to embark on a metabolomics research programme and includes the fundamentals of chromatography alongside the latest developments in the field.

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Interest in the application of nanotechnology to medicine has surged in recent years and could transform the way we diagnose, treat and prevent diseases such as cancer. However, the clinical success of nanomedicine is limited because of problems with toxicity and therapeutic efficacy. To overcome this it is essential to produce new nanosystems with specific functions, which can be achieved by designing new polymers with particular properties that can be used for nanomedicine. Functional Polymers for Nanomedicine provides a complete overview of the different strategies for designing polymers for nanomedicine applications. The first part of the book looks at the current problems and direction in nanomedicine including a review of current design and targeting of nanocarriers. The second part explores the design of polymers with different functions including hyperbranched polymers, polymersomes, polysaccharides, polymeric micelles and zwitterionic polymers and their applications in gene therapy and drug delivery. This timely book is edited by a leading scientist in nanomedicine and provides a suitable introduction and reference source for advanced undergraduates, postgraduates and academic and industrial researchers in polymer science, nanotechnology and pharmacy interested in materials for medical applications.

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Introducing astrochemistry to a wide audience, this book describes how molecules formed in chemical reactions occur in a range of environments in interstellar and circumstellar space, from shortly after the Big Bang up to the present epoch. Stressing that chemistry in these environments needs to be driven, it helps identify these drivers and the various chemical networks that operate giving rise to signature molecules that enable the physics of the region to be better understood. The book emphasises, in a non-mathematical way, the chemistry of the Milky Way Galaxy and its planet-forming regions, describes how other galaxies may have rather different chemistries and shows how chemistry was important even in the Early Universe when most of the elements had yet to be formed. This book will appeal to anyone with a general interest in chemistry, from students to professional scientists working in interdisciplinary areas and non-scientists fascinated by the evolving and exciting story of chemistry in the cosmos.

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Everyone is becoming more environmentally conscious and therefore, chemical processes are being developed with their environmental burden in mind. This also means that more traditional chemical methods are being replaced with new innovations and this includes new solvents. Solvents are everywhere, but how necessary are they? They are used in most areas including synthetic chemistry, analytical chemistry, pharmaceutical production and processing, the food and flavour industry and the materials and coatings sectors. However, the principles of green chemistry guide us to use less of them, or to use safer, more environmentally friendly solvents if they are essential. Therefore, we should always ask ourselves, do we really need a solvent? Green chemistry, as a relatively new sub-discipline, is a rapidly growing field of research. Alternative solvents - including supercritical fluids and room temperature ionic liquids - form a significant portion of research in green chemistry. This is in part due to the hazards of many conventional solvents (e.g. toxicity and flammability) and the significant contribution that solvents make to the waste generated in many chemical processes. Solvents are important in analytical chemistry, product purification, extraction and separation technologies, and also in the modification of materials. Therefore, in order to make chemistry more sustainable in these fields, a knowledge of alternative, greener solvents is important. This book, which is part of a green chemistry series, uses examples that tie in with the 12 principles of green chemistry e.g. atom efficient reactions in benign solvents and processing of renewable chemicals/materials in green solvents. Readers get an overview of the many different kinds of solvents, written in such a way to make the book appropriate to newcomers to the field and prepare them for the 'green choices' available. The book also removes some of the mystique associated with 'alternative solvent' choices and includes information on solvents in different fields of chemistry such as analytical and materials chemistry in addition to catalysis and synthesis. The latest research developments, not covered elsewhere, are included such as switchable solvents and biosolvents. Also, some important areas that are often overlooked are described such as naturally sourced solvents (including ethanol and ethyl lactate) and liquid polymers (including poly(ethyleneglycol) and poly(dimethylsiloxane)). As well as these additional alternative solvents being included, the book takes a more general approach to solvents, not just focusing on the use of solvents in synthetic chemistry. Applications of solvents in areas such as analysis are overviewed in addition to the more widely recognised uses of alternative solvents in organic synthesis. Unfortunately, as the book shows, there is no universal green solvent and readers must ascertain their best options based on prior chemistry, cost, environmental benefits and other factors. It is important to try and minimize the number of solvent changes in a chemical process and therefore, the importance of solvents in product purification, extraction and separation technologies are highlighted. The book is aimed at newcomers to the field whether research students beginning investigations towards their thesis or industrial researchers curious to find out if an alternative solvent would be suitable in their work.

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Approaching the literature in a subject such as electrochemistry can be daunting. Specialist Periodical Reports present comprehensive and critical reviews of the current literature, with contributions from across the globe, providing the reader with an informed digest of the most important research currently carried out in the field. Re-launched in 2012 with a new editorial team (Compton and Wadhawan), this latest volume covers a broad range of topics, all with an emphasis on the nano aspects of electrochemistry. Aside from the applied chapters, contributions have also been submitted which examine eletrochemistry in specific regions; China and India are covered in this volume.

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Organophosphorus Chemistry provides a comprehensive and critical review of the recent literature. Coverage includes phosphines and their chalcogenides, phosphonium salts, low coordination number phosphorus compounds, penta- and hexa- coordinated compounds, quinquevalent phosphorus acids, nucleotides and nucleic acids, ylides and related compounds, phosphazenes and the application of physical methods in the study of organophosphorus compounds.

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Soil is essential to agriculture and a resource that cannot be replaced easily. Nevertheless, its importance to food production and the threats to its sustainability are often overlooked. This book, the 35th volume of Issues in Environmental Science and Technology, examines the current status of soils across the globe and their potential for food production to meet the needs of the World's population in the 21st Century. Threats, such as the degradation, pollution and erosion of soil are discussed, along with the possible consequences of climate change for soil and food production. As an ecosystem service, soil also serves to capture nutrients and sequester carbon, and these issues are discussed in the context of adding value to soil protection. The influence of modern agricultural techniques in enhancing soil productivity is also discussed. Throughout the book case studies support the discussion. Together with the books on Ecosystem Services, Sustainable Water, and Environmental Impacts of Modern Agriculture, this addition to the series will be essential reading for anyone concerned with the environment, whether as scientist, policy maker, student or lay reader.

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Comprehensive Biomarker Discovery and Validation for Clinical Application provides the reader with an extensive introduction into all aspects of proteomics biomarker discovery, validation and development. It discusses the current status of science and technology, its limitations, bottlenecks as well as future development trends to improve the success rate of translating biomarker discovery into useful clinical tests. The most important feature of the book is to provide an overview of current technologies and the challenges encountered during biomarker discovery and validation, such as patient selection, sample handling, data processing, statistical analysis and registration and approval of validated biomarkers through European and US regulatory authorities. The authors introduce the reader to each of these topics in significant detail and provide examples or guidelines for best practice. There are prominent chapters included on biomarkers in translational and personalised medicine; an introduction to regulatory affairs and bring biomarkers to the market; biomarker discovery and the use of mass spectrometry based profiling platforms; MALDI imaging techniques in tissue-based biomarkers discovery and a clinical application study on the use of diagnostic assays for early diagnosis of heart failure using various proteomic methods. The book concludes with a final chapter on future trends in biomarker discovery and validation. The book targets a readership of industrial and academic researchers that are involved in biomarker discovery and validation or that manage biobanks, develop sample preparation methods, analytical profiling systems and bioinformatics tools. Common pitfalls and success stories in biomarker discovery are highlighted and guidelines for best practice are provided for the different parts of the procedure. The book will be an essential information resource for scientists working in the field.

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Bioanalytical applications in nanopores are an exciting field of research which have seen rapid development over the last ten plus years. This book focuses uniquely on this research area providing an insight from the world leading experts in the area. Based on the proceedings of the 1st International Conference on Nanopores for Bioanalytical Applications (Lanzarote, 2012), it will provide a snapshot of this exciting field for the nanopores community. It describes the latest experimental and fabrication protocols necessary to carry out nanopore-based experiments and covers a wide variety of topics. These include: biological pores, solid state pores, hybrid structures, fundamental aspects, work on the underlying (bio)physics and applications in biosensing and DNA sequencing. The multidisciplinary approach to this topic makes the book suitable for readers in both academia and industry.

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Gas-cooled, graphite-moderated nuclear reactors suffer ageing and degradation to the graphite during service posing a threat to the functionality of the core, and potentially, the safe operation of the reactor. Thus, the importance of modelling and measuring reactor core graphite properties and performance increases especially as continued use beyond the designed life time becomes significant. This book captures the proceedings from the third in a series of meetings addressing the extensive research and analysis performed to ensure the continuing safe performance of the graphite cores. Covering four broad themes: mechanistic; statistical; empirical; and, plant performance, this book should appeal to a wide range of readers from engineers and reactor operators to policy makers.

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This publication includes peer-reviewed manuscripts from the 2011 International Network of Environmental Forensics (INEF) Conference held at St John's College in Cambridge, UK. INEF is an organization founded by environmental forensic scientists for the express purpose of sharing and disseminating environmental forensic information to the international scientific community. Environmental forensic information presented at this conference included topics on contaminant age dating, the use of chemical and biological diagnostic markers for contaminant source identification, advancements in the use of petroleum hydrocarbon pattern recognition techniques, the availability of surrogate chemicals to identify the age of a contaminant release, the identification and application of chemical impurities for source identification and advancements in compound specific isotopic analysis, especially related to chlorinated solvent releases. All of these topics were presented in terms of their applications in contaminant releases throughout the world in terrestrial and marine environments. This professionally edited book is the second of a series of INEF conference publications chronicling the current state of the art in environmental forensics. The intent of this publication and subsequent INEF conference volumes is to capture the evolution of environmental forensic topics as a scientific discipline.

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Over the past decade there has been a resurgence of interest in growing fruit and vegetables in the garden and on the allotment. Part of the driving force behind this is an increased awareness of the health benefits that can be derived from fruit and vegetables in the diet. The 'five helpings a day' dictum reflects the correlation between a regular consumption of fruit and vegetables and a reduced incidence of, for example, cardiovascular disease and some cancers. Growing your own vegetables provides the opportunity to harvest them at their peak, to minimize the time for post-harvest deterioration prior to consumption and to reduce their 'food miles'. It also provides an opportunity to grow interesting and less common cultivars. The combination of economic advantages and recreational factors add to the pleasure of growing fruit and vegetables. This book covers the natural products that have been identified in common 'home-grown' fruit and vegetables and which contribute to their organoleptic and beneficial properties. Over the last fifty years the immense advances in separation methods and spectroscopic techniques for structure elucidation have led to the identification of a wide range of natural products in fruit and vegetables. Not only have many of their beneficial properties been recognized but also their ecological roles in the development of plants have been identified. The functional role of many of these natural products is to mediate the balance between an organism and its environment in terms of microbial, herbivore or plant to plant interactions. The book is aimed at readers with a chemical background who wish to know a little more about the natural products that they are eating, their beneficial effects, and the roles that these compounds have in nature. Developments in the understanding of the ecological and beneficial chemistry of fruit and vegetables have made the exploration of their chemical diversity a fascinating and expanding area of natural product chemistry and readers will obtain some 'taste' for this chemistry from the book. It develops in more detail the relevant sections from the earlier RSC book 'Chemistry in the Garden'. The book begins with an outline of the major groups of compound that are found in fruit and vegetables. This is followed by a description of aspects of environmental chemistry that contribute to the successful cultivation of these crops. Subsequent chapters deal with individual plants which are grouped in terms of the part of the plant, roots, bulbs and stems, leaves, seeds, that are used for food. The final chapters deal with fruit and herbs. The epilogue considers some general aspects of ecological chemistry and climatic stress which may, in the future, affect the growth of fruit and vegetables in the garden particularly in the context of potential climate changes. The book concludes with a section on further reading, a glossary of terms used in plant chemistry and a list of the common fruit and vegetables grouped in their plant families.

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Polyamines are ubiquitous molecules that are involved in a number of important cellular processes. Aberrations in their function or metabolism play a role in diseases such as cancer and parasitic infection. A number of validated drug targets have been identified, including enzymes in the polyamine biosynthetic and catabolic pathways and the S-adenosylmethionine synthetic and salvage pathways. Polyamine Drug Discovery is the first comprehensive volume to cover all aspects of the design and development of potential therapeutics targeting polyamine metabolism. The book details research progress from 1975 to the present date and discusses the design and use of polyamine metabolism inhibitors as therapeutic agents. Various polyamine-containing drugs are described that can be used in chemotherapy, and as treatments for infections including trypanosomiasis, leishmaniasis and malaria. Finally, the roles of polyamine analogues in chemoprevention, polyamine-containing vectors for gene delivery, and the design of polyamine-based epigenetic modulators are detailed. Each chapter addresses a different aspect of polyamine drug discovery and all are written by medicinal and biological chemists with particular expertise in developing agents that modulate polyamine metabolism or function. The book will increase the visibility of polyamine drug discovery among pharmaceutical researchers and provide a valuable reference for everyone working in the field.

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Ion channel drug discovery is a rapidly evolving field fuelled by recent, but significant, advances in our understanding of ion channel function combined with enabling technologies such as automated electrophysiology. The resurgent interest in this target class by both pharmaceutical and academic scientists was clearly highlighted by the over-subscribed RSC/BPS 'Ion Channels as Therapeutic Targets' symposium in February 2009. This book builds on the platform created by that meeting, covering themes including advances in screening technology, ion channel structure and modelling and up-to-date case histories of the discovery of modulators of a range of channels, both voltage-gated and non-voltage-gated channels. The editors have built an extensive network of contacts in the field through their first-hand scientific experience, collaborations and conference participation and the organisation of the meeting at Novartis, Horsham, increased the network enabling the editors to draw on the experience of eminent researchers in the field. Interest and investment in ion channel modulation in both industrial and academic settings continues to grow as new therapeutic opportunities are identified and realised for ion channel modulation. This book provides a reference text by covering a combination of recent advances in the field, from technological and medicinal chemistry perspectives, as well as providing an introduction to the new 'ion channel drug discoverer'. The book has contributions from highly respected academic researchers, industrial researchers at the cutting edge of drug discovery and experts in enabling technology. This combination provides a complete picture of the field of interest to a wide range of readers.

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Multivariate analysis of the multi-component analytical profiles of carefully collected biofluid and/or tissue biopsy specimens can provide a 'fingerprint' of their biomolecular/metabolic status. Therefore, if applied correctly, valuable information regarding disease indicators, disease strata and sub-strata and disease activities can be obtained. This exemplary new book highlights applications of these techniques in the areas of drug therapy and toxicology, cancer, obesity and diabetes, as well as outlining applications to cardiovascular, infectious, inflammatory and oral diseases in detail. The book gives particular reference to cautionary measures that must be applied to the diagnosis and classification of these conditions or physiological criteria. Comprehensively covering a wide range of topics, of particular interest is the focus on experimental design and 'rights and wrongs' of the techniques commonly applied by researchers, and the very recent development of powerful 'Pattern Recognition' techniques. The book provides a detailed introduction to the area, applications and common pitfalls of the techniques discussed before moving into detailed coverage of specific disease areas, each highlighted in individual chapters. This title will provide an invaluable resource to Medicinal chemists, Biochemists and toxicologists working in industry and academia.

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In order to understand the basic aspects of an electrochemical investigation on inorganic molecules (in its widest meaning, of any molecule which contains at least one metal centre) it must be taken into account that in these molecules the metal-ligand bonds are of the prevailingly covalent type. Since electrochemical techniques allow you to add or remove electrons in a controlled manner, it is conceivable that the addition or removal of electrons inside these molecules can lead to the formation of new bonds or to the breakage of existing bonds. The main aim of this book is to study the effects of such electron addition and removal processes on the molecular frames. The second edition of this classic book has been fully revised and updated and is a straightforward, logical introduction to electrochemical investigations for inorganic chemists. All chapters have been rewritten with new material including: - the addition of reactivity with nitric oxide to the chapter on the reactivity of metal complexes with small molecules - thiolate-protected gold nanoclusters has been added to the chapter on metal-sulfur and metal-carbonyl clusters - a new chapter on the digital simulation of electrochemical responses - a new chapter on the theoretical calculations to explain the nature of the electrochemical activity of metal complexes - new chapters on spectroelectrochemistry and electrochemiluminescence. The book covers every aspect of inorganic electrochemistry - the introduction is followed by chapters on the basic aspects of electrochemistry followed by practical and applicative aspects and ends with full appendices. It is probably the only publication with a simple approach to electrochemical aspects of the topics in inorganic chemistry. Bridging the gap between undergraduate and research-level electrochemistry books, this publication will be a welcome addition to the literature of inorganic chemists. It will also be particularly useful to final year students in chemistry and as background reading for graduates and researchers without adequate electrochemical knowledge to become active in the discipline or who want to collaborate with electrochemists.

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Human biomonitoring has developed from a research tool in occupational and environmental health to identify and quantify exposures to harmful substances in urine and blood. The analytical methods for detection of substances in biological media have considerably improved with smaller detection limits and more precise and specific measurements. Human biomonitoring is a valuable tool in exposure estimation of selected populations and currently used in surveillance programs all over the world. This two volume set provides an overview of current available biomarkers and human biomonitoring programs in environmental health, which is timely given the present debate on adverse health effects from environmental exposures. The books decribe both previous and ongoing studies as well as the newer biomarkers of exposure and effects. Volume one describes current human biomonitoring programs in Germany, Romania, France, Canada, India and Belgium, providing convincing evidence of a global decline in h

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Biophysical Chemistry covers the physical chemistry of biological macromolecules and the experimental techniques used to study them. Topics covered include: an introduction to biological molecules; spectroscopy, mass spectrometry and hydrodynamics of macromolecules; a ""bluffer's guide"" to molecular thermodynamics; biomolecular kinetics; chromatography and electrophoresis; and single-molecule methods. The easily digestible, pragmatic approach captures the reader with the fascinating challenges the subject poses for theoretical and experimental scientists. This book will be ideal for early undergraduates studying chemical or physical sciences and will act as a basis for more advanced study. Students in other areas of biological sciences will appreciate the less intimidating approach to physical chemistry as demonstrated here. Ideal for the needs of undergraduate chemistry students, Tutorial Chemistry Texts is a major series consisting of short, single topic or modular texts concentrating on the fundamental areas of chemistry taught in undergraduate science courses. Each book provides a concise account of the basic principles underlying a given subject, embodying an independent-learning philosophy and including worked examples.

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Revised, updated and expanded Basic Water Treatment remains an essential reference on all aspects of water quality and treatment systems. A bestselling text, this book has been written by two of the world’s leading experts in the field and remains the definitive reference for all those involved in water treatment systems. This widely-accepted introduction and practical guide to water treatment focuses on the issues of most interest to practising engineers, summarising the key issues and criteria in short and accessible sections with additional theory to explain and support the treatment processes considered. The book also presents up-to-date information on UK, European and American water-quality standards, including the 2007 amendments to the English and Welsh drinking water regulations. Expanding further on topics such as membrane processes and water demands, the fourth edition includes a new section on water re-use, and two new chapters on water safety plans and private water supplies. Basic Water Treatment is an essential resource for water engineers at all levels. Ideal as a textbook for students, a handbook for young engineers or chemists, and an indispensable guide full of practical information for the established practitioner.

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Atmospheric Chemistry provides readers with a basic knowledge of the chemistry of Earth's atmosphere, and an understanding of the role that chemical transformations play in this vital part of our environment. The composition of the 'natural' atmosphere (troposphere, stratosphere and mesosphere) is described in terms of the physical and chemical cycles that govern the behaviour of the major and the many minor species present, and of the atmospheric lifetimes of those species. An extension of these ideas leads to a discussion of the impacts of Man's activities on the atmosphere, and to an understanding of some of the most important environmental issues of our time. One thread of the book explains how living organisms alter the composition and pressures in the atmosphere, modify temperatures, and change the intensity and wavelength-distribution of light arriving from the Sun. Meanwhile, the living organisms on Earth have depended on these very same environmental conditions being satisfactory for the maintenance and evolution of life. There thus appear to be two-way interactions between life and the atmosphere. Man, just one species of living organism, has developed an unfortunate ability to interfere with the feedbacks that seem to have maintained the atmosphere to be supportive of surface life for more than 3.5 billion years. This book will help chemists to understand the background to the problems that arise from such interference. The structure of the book and the development of the subject deviate somewhat from those usually encountered. Important and recurring concepts are presented in outline first, before more detailed discussions of the atmospheric behaviour of specific chemical species. Examples of such themes are the sources and sinks of trace gases, and their budgets and lifetimes. That is, the emphasis is initially on the principles of the subject, with the finer points emerging at later points in the book, sometimes in several successive chapters. In this way, some of the core material gets repeated exposure, but in new ways and in new contexts. The book is written at a level that makes it accessible to undergraduate chemists, and in a manner that should make it interesting to them. However, the material presented forms a solid base for those who are extending their studies to a higher level, and it will also provide non-specialists with the background to an understanding of Man's several and varied threats to the atmosphere. Well-informed citizens can then better assess measures proposed to prevent or alleviate the potential damage, and policy makers more realistically formulate the necessary controls on a sound scientific foundation.

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In the late 1990s, there was an explosion of research on ionic liquids and they are now a major topic of academic and industrial interest with numerous existing and potential applications. Since then, the number of scientific papers focusing on ionic liquids has risen exponentially, including a few edited multi-author books covering the latest advances in ionic liquids chemistry and several volumes of symposium proceedings. Much of the content in these books and volumes is written using technical jargon that only scientists at the cutting edge of ionic liquids research will understand and ionic liquids are hardly covered in most modern chemistry textbooks. This is the first single-author book on ionic liquids and the first introductory book on the topic. It is written in a clear, concise and consistent way. The book provides a useful introduction to ionic liquids for those readers who are not familiar with the topic. It is also wide ranging, embracing every aspect of the chemistry and applications of ionic liquids. The book draws extensively on the primary scientific literature to provide numerous examples of research on ionic liquids. These examples will enable the reader to become familiar with the key developments in ionic liquids chemistry over recent years. The book provides an introduction to: ionic liquids; their nomenclature; history; physical, chemical and biological properties; and their wide ranging uses and potential applications in catalysis, electrochemistry, inorganic chemistry, organic chemistry, analysis, biotechnology, green chemistry and clean technology. Notable and important chapters include "The Green Credentials of Ionic Liquids" and "Biotechnology." The chapter on "Applications" includes sections with brief descriptions of recent research on the development of ionic liquids: - for the construction of a liquid mirror for a moon telescope - for use as rocket propellants - for use as antimicrobial agents that combat MRSA - as active pharmaceutical ingredients and antiviral drugs - for embalming and tissue preservation Science students, researchers, teachers in academic institutions and chemists and other scientists in industry and government laboratories will find the book an invaluable introduction to one of the most rapidly advancing and exciting fields of science and technology today.

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There has been increasing research into designing transition metal-containing dendrimers as innovative materials, especially in the field of biomedicine and pharmaceutical science. They have applications in biosensors and drug-delivery systems, and are now one of the leading classes in the design of therapeutics for drug-resistant diseases. This book introduces readers to a number of classes of metal-containing dendrimers, before moving onto their design and synthesis. Their applications in biomedicine are then discussed, before highlighting future research targets in this growing field. It emphasizes the synthetic strategies to design transition metal-containing dendrimers, and discusses the type of laboratory work used to examine these types of dendrimers in the fields of medicine and pharmacology, including their antimicrobial, anticancer, anti-inflammatory and antiviral activities. Transition Metal-Containing Dendrimers in Biomedicine brings chemistry, biology, pharmaceutical science and medical fields together to design these future materials which will have global benefits.

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Historically the field of heterogeneous catalysis has focused on the design and optimisation of the catalytic materials. However, as these optimisations start to reach diminishing returns, attention has turned to non-conventional means for improving reaction conditions such as the use of ultrasound, plasma, electromagnetic heating and microwave heating. Microwave-assisted catalysis has been demonstrated to be useful in a wide range of applications including ammonia synthesis, desulfurization and production of chemicals from biomass. Advances in Microwave-assisted Heterogeneous Catalysis begins with the basics of microwave heating and the role of microwaves in heterogeneous catalysis. It goes on to cover the mechanisms of microwave specific reaction rate enhancement, microwave-assisted synthesis of porous, nonporous and supported metal catalysts, microwave augmented reactor technology and microwave-induced catalysis. The application of microwave-assisted heterogeneous catalysis in various fields of energy conversion, environmental remediation, and bulk and specialty chemicals synthesis are also discussed, making this a great reference for anyone involved in catalysis research.

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Superhydrophobic coatings have attracted substantial scientific research in recent years due to their real-world applications in a variety of fields including anti-corrosion, anti-icing, anti-fogging, oil separation and self-cleaning materials. Several approaches and methods have been used in developing superhydrophobic coatings on different substrates. This book guides readers through their fabrication and application, representing the latest significant advances in this important topic. Split into four sections, Part One concentrates on the fundamental principles of surface wettability and superhydrophobicity, before moving into Part Two and Part Three, which focus on different aspects of superhydrophobic coatings based on the materials used for fabrication and the substrate on which the coating is applied. Finally, Part Four focuses on the applications of these coatings. This book will serve as a valuable reference for graduate students, researchers and industrial practitioners in multiple industries working on surface wettability, materials chemistry and coatings related technologies.

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Building upon the previous volumes, The Chemical Biology of Sulfur, The Chemical Biology of Phosphorus, and The Chemical Biology of Nitrogen, this book examines the organic chemistry of life, The Chemical Biology of Carbon. It examines chemical biology open to carbon-containing natural metabolites that allow both retrospective and predictive behaviours of both biosynthetic and degradative metabolism in primary and secondary pathways. This book also notes the centrality of a core set of heterocycles in metabolites and coenzyme forms of vitamins and how that chemistry enables life. The organic chemical fundamental considerations are always tied to specific metabolites and metabolic transformations. This context makes this volume not a classical organic or even bioorganic approach to organic chemistry in vivo but instead a unique analysis of how the rules and reactivities of organic chemistry underlie the organic chemistry of life. The Chemical Biology of Carbon is an ideal reference and guide for medicinal chemists, chemical biologists, organic chemists as well as postgraduate, graduate and advanced undergraduate students in these areas and related disciplines.

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As a result of their unique physical properties, biological membrane mimetics such as biopolymers are used in a broad range of scientific and technological applications. This comprehensive book covers new applications of biopolymers in the research and development of industrial scale nutraceutical and functional food grade products. All the major food biopolymers are included, from plant, animal and marine sources. Coverage also includes biopolymer-based drug delivery mechanisms intended for biological applications such as bio-detection of pathogens, fluorescent biological labels, and drug and gene delivery. This is the first interdisciplinary book to address this area specifically and is essential reading for those who produce the functional biopolymer materials as well as those who seek to incorporate them into appropriate nutraceutical, food and drug delivery products.

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This book discusses the present and the future perspectives of NMR techniques for environmental evaluations.

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Many of the polymers we use every day are highly flammable. Historically, a large number of home fires were caused by ignited polymeric materials until legislation was introduced requiring fire retardants to be added to these materials. Fire retardants increase the time it takes for materials to ignite, providing valuable time to prevent a fire or escape. However, it has become apparent that many of the traditional treatments used as fire retardants are harmful to human health and highly persistent in the environment. With evermore polymeric materials in our homes and lives it is still highly valuable to be able to make fire retardants, but consideration must be given to their environmental impact and sustainability. Green Fire Retardants for Polymeric Materials looks at both the choice of different materials and treatments for improving the fire retardancy of polymeric materials, as well as green approaches to synthesising these fire retardants. It is a timely resource both for green chemists interested in real world applications for their work and polymer scientists keen to increase the sustainability of their products and processes.

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Ammonia oxidising bacteria (AOB) and archaea are ubiquitous microorganisms, but their abundance and diversity vary widely across environments and play a crucial role in many ecosystems and aquatic ecosystems in particular. However, characterization of AOB communities require genomic methods as they are difficult to isolate from samples. Although non-toxic to humans, in the short term, ammonia in water systems are harmful to aquatic life both directly and indirectly through the disruption of the ecosystem by promoting the proliferation of algae (a process called eutrophication). Contamination often occurs due to use of disinfectants with chloramines, fertilizers, waste disposal and from natural processes. Due to their natural presence, utilising AOBs to treat water is viewed as an attractive solution, but greater knowledge of their biochemical processes and measurement of their efficacy is required. Ideal for postgraduates and researchers in a variety of disciplines, this book covers the ecology, genomics, physiology and biochemistry of AOBs and their presence in wastewater, and the challenges, opportunities and potential applications for nitrification and ammonia removal.

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Fungal natural products are among some of the earliest described sources of bioactive compounds. Basidiomycetes have been a prolific source of compounds, particularly as a source of antibiotics and antifungals. Despite advances in target-based and synthetic methods for drug discovery, natural products continue to be an important source of novel compounds. This book is a comprehensive guide to many important fungal species with a focus on their phytochemistry, potential sources of bioactive compounds, known chemistry and toxicology. This book is an ideal companion to researchers and postgraduates in phytochemistry and natural product pharmacology, and mycologists.

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Cosmetics manufacture is a dynamic and vibrant industry with companies varying from the very small scale, working in their own home, to much larger enterprises. With such variable companies there is the risk of equally variable quality in manufacturing. The International Organization for Standards (ISO) provides guidelines on good manufacturing processes for the cosmetics industry. However, not everyone working in cosmetics has a scientific or engineering backgrounds and understanding and meeting the ISO requirements can be daunting. Whether you are a small business just starting out or an established company looking to expand, Making Quality Cosmetics will guide you through the requirements of the ISO standard. Calling on more than 35 years of experience in the cosmetics sector the author covers every aspect of the manufacturing set up and process, as well as discussing other regulations that may need to be considered, especially in larger facilities. With technical advice ranging from choosing equipment and raw materials, to assessing and auditing contractors this book will help you make sure your products are of the highest quality.

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This book provides an accessible overview of the historical background of the chemistry of flexible metal-organic frameworks (MOFs) and their features.

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Polysaccharides are natural, renewable materials that are biodegradable and biocompatible, making them ideal subjects for biomedical applications. This book focusses on the main polysaccharides, including but not limited to chitosan, cellulose, alginate, dextran, guar gum, gellan gum, pullulan, locust bean gum, pectin, xanthan gum, starch, hyaluronan and carrageenan, and their applications in drug delivery, imaging and tissue engineering. With contributions from around the world, the editors have pulled together a tightly curated set of chapters which showcase how polysaccharide-based materials are employed in a range of biomedical systems. The end result is a book in which the reader can gain a sound overview of this important class of material for biomedical applications, without scouring journal articles. Those working in materials science, biomedical and chemical engineering, and pharmaceutical technologies will find this a must-have reference.

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Nanopollutants are nanoparticles that have escaped into the environment and can include engineered nanoparticles as well as nanoparticles that are products of degradation (e.g. nanoplastics) or other processes. As many of these particles are only recently developed or described there is still a lot to learn about where they come from, where they end up and what risks they pose to health and the environment. Offering a wide overview of the most recent research on these emerging contaminants, from the investigation of their sources and fate to the analytical developments for their detection and analysis, this book gives the reader a full picture of the global research on engineered and natural nanoparticles in the environment. Taking a forward-looking perspective with chapters on new nanopollutants, regulatory direction and occurrence in different environmental compartments, this book is a great resource for anyone working in environmental chemistry, nanoscience or environmental regulation.

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This volume brings together the wide range of scientists working on metaloxygen batteries to exchange ideas on the challenges and prospects in this field.

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Designed for teaching, this English translation of the tried and tested Organometallic Chemistry 2/e textbook from the Japan Society of Coordination Chemistry can be used as an introductory text for chemistry undergraduates and also provide a bridge to more advanced courses. The book is split into two parts, the first acts as a concise introduction to the field, explaining fundamental organometallic chemistry. The latter covers cutting edge theories and applications, suitable for further study. Beginning with fundamental reaction patterns concerning bonds between transition metals and carbon atoms, the authors show how these may be combined to achieve a desired reaction and/or construct a catalytic cycle. To understand the basics and make effective use of the knowledge, numerous practice questions and model answers to encourage the reader’s deeper understanding are included. The advanced section covers the chemistry relating to bonds between transition metals and main group elements, such as Si, N, P, O and S, is described. This chemistry has some similarities to transition metal-carbon chemistry, but also many differences and unique aspects, which the book explains clearly. Organometallic complexes are now well known and widely used. In addition, transition metal complexes with main group element other than carbon as a ligating atom are becoming more important. It is thus important to have a bird’s-eye view of transition metal complexes, regardless of the ligand type. This book acts as solid introduction for chemistry students and newcomers in various fields who need to deal with transition metal complexes.

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Modern societies produce large amounts of waste of many different types. This presents a problem in terms of management or disposal to prevent harm to human health and the environment. Additionally it represents a loss of potentially useful resources. In the circular economy concept nothing would ever become waste because everything would be re-usable or its components recoverable. Ionic liquids provide a potential route for valorisation of different waste types, paving the way for a circular economy and a more sustainable world. Covering various types of waste, including municipal, industrial, electronic, and medical, while addressing patented and commercial applications, this book aims to deliver a comprehensive, but also critical, perspective on the application of ionic liquids towards waste valorisation. Waste Valorisation Using Ionic Liquids is a useful resource for academic and industrial players, in the fields of chemistry, chemical and environmental engineering, and biotechnology, as well as anyone working on waste management and resource recovery.

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Take a colorful walk through human ingenuity. Humans have been unpacking the earth to use pigments since cavemen times. Starting out from surface pigments for cave paintings, we’ve dug deep for minerals, mined oceans for colors and exploited the world of plants and animals. Our accidental fumbles have given birth to a whole family of brilliant blues that grace our museums, mansions and motorcars. We’ve turned waste materials into a whole rainbow of tints and hues to color our clothes, our food and ourselves. With the snip of a genetic scissor, we’ve harnessed bacteria to gift us with “greener” blue jeans and dazzling dashikis. As the pigments march on into the future, who knows what new and exciting inventions will emerge? Mary Virginia Orna, a world-recognized expert on color, will lead you through an illuminating journey exploring the science behind pigments. Pausing for reflections en route to share stories around pigment use and discoveries informed by history, religion, sociology and human endeavour, this book will have you absorbing science and regaling tales. Jam packed with nuggets of information, March of the Pigments will have the curiously minded and the expert scientist turning pages to discover more.

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Nanotechnology is a promising technique that can facilitate sustainability across a wide range of areas. By fabricating materials into nanometre-scale, nanotechnology has facilitated an efficient, economically, and environmentally acceptable solution for waste treatment and energy production. This book illustrates how green nanotechnology is being used to promote sustainability, including applications in environmental remediation and energy optimization. First, a comprehensive discussion of the latest advances to address the global challenges in water purification, CO2 management, plastics issue, food waste valorisation, toxic chemical pollutes, and energy efficiency will be provided. This is followed by the new opportunities that have been created in the production of alternative renewable energy under the premise of low natural resource consumption and minuscule toxicity production. Offering an important reference for the research community to understand more about green nanotechnology and its applications in sustainable development and circular economy. The book will be of interest to graduate students and researchers in nanotechnology, materials science, sustainability, environmental science, and energy.

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Written for senior undergraduate and graduate students, as well as those chemists unfamiliar with “frustrated Lewis pairs (FLPs)”, this text serves as an introduction to the both the concept and application of FLPs in hydrogenation catalysis. The book begins by setting the stage as it was around the turn of the century. While the dramatic impacts of catalysis were undeniable, there was dependence of such technologies on transition metal chemistry. Contrastingly, the chemistry of main group elements was dominated by Lewis acid-base behavior. However, these perceptions were altered with the discovery of the ability of “frustrated Lewis pairs (FLPs)” to activate dihydrogen. The basic features, and mechanisms of action of these unique main group systems are chronicled, while the evolution of the initial findings to applications in catalytic hydrogenation is discussed. A subsequent chapter focuses on the breadth of organic substrates for which borane based FLP hydrogenations are effective. This is furthered with a chapter on the metal-free enantioselective reductions. FLP chemistry is not limited to systems involving boranes and this book also catalogues a range of FLP hydrogenation catalysts involving elements from across the periodic table. The final chapter in the book describes other directions of interest where the application of the concept of FLPs hydrogenation are beginning to emerge. Ideal for course use and self study, this book provides synthetic chemists with a fresh, expert introduction to the field. The reader will be left recognizing that hydrogenation catalysts is a domain no longer limited to transition metals.

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The exploration of new-family desalination techniques has become increasingly important in recent decades. Capacitive deionization (CDI) has attracted multidisciplinary interest as a promising alternative to the conventional desalination techniques of reverse osmosis and electro-osmosis, due to several attractive features such as low energy consumption, environmental friendliness, and high water utilization efficiency. CDI desalts saline water through storing ions in electrical double layers of porous carbons or by redox reactions with faradic materials. This is the first book to specialise in CDI and aims to showcase the fundamentals and progressive achievements of the research. Chapters cover the timeline of CDI technologies, the expansion of new-family electrode materials, exploitation of new-concept CDI devices, and applications of CDI in other new areas. In addition, the book provides new insights into future directions for the development of CDI and other emerging nanotechnologies for addressing the energy-water nexus. Edited by a founder of the field, the book will be of interest to those researching water desalination and purification across chemistry, materials science and environmental science.

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