Search results for ""elsevier science publishing co inc""

The Handbook of Organic Compounds: NIR, IR, Raman, and UV-Vis Spectra Featuring Polymers and Surfactants represents a compendium of practical spectroscopic methodology, comprehensive reviews, and basic information for organic materials, surfactants, and polymer spectra covering the Ultraviolet, Visible, Near Infrared, Infrared, Raman and Dielectric measurement techniques. This set represents a complementary organic compound handbook to the Nyquist inorganic handbook, published in 1996. This set comprises the first comprehensive multi-volume handbook to provide basic coverage for UV-Vis, 4th overtone NIR, 3rd overtone NIR, NIR, Infrared, Raman spectra, and Dielectric data for common organic compounds, polymers, surfactants, contaminants, and inorganic materials commonly encountered in the laboratory. The text includes a description and reviews of interpretive and chemometric techniques used for spectral data analysis. The spectra included within the atlas are useful for identification purposes as well as pedagogical for the instruction of the various interpretive and data processing methods discussed. This work is designed to be of help to students and vibrational spectroscopists in their efforts of daily spectral interpretation and data processing of organic spectra, polymers, and surfactants. All spectra are presented in wavenumber and transmittance, with the addition of ultraviolet, visible, 4th overtone NIR, 3rd overtone NIR, and NIR spectra also represented in nanometers and absorbance space. In addition, some Horizontal infrared ATR spectra are presented in wavenumber and absorbance space. All spectra are shown with essential peaks labeled in their respective units. The material in this handbook was contributed to by several individuals, and comments were received from a variety of prominent workers in the field of molecular spectroscopy. This type of handbookproject is a daunting task. This Handbook can provide a valuable reference for the daily activities of students and professionals working in modern molecular spectroscopy laboratories.

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Thorp and Covich's Freshwater Invertebrates: Keys to Nearctic Fauna, Fourth Edition presents a comprehensive revision and expansion of this trusted professional reference manual and educational textbook—from a single North American tome into a developing multivolume series covering inland water invertebrates of the world. Readers familiar with the first three editions will welcome this new volume. The series, now entitled Thorp and Covich’s Freshwater Invertebrates, (edited by J.H. Thorp), began with Volume I: Ecology and General Biology, (edited by J.H. Thorp and D.C. Rogers). It now continues in Volume II with taxonomic coverage of inland water invertebrates of the Nearctic zoogeographic region. As in previous editions, all volumes of the fourth edition are designed for multiple uses and levels of expertise by professionals in universities, government agencies, and private companies, as well as by undergraduate and graduate students.

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This fifth edition of the classic textbook in plant pathology outlines how to recognize, treat, and prevent plant diseases. It provides extensive coverage of abiotic, fungal, viral, bacterial, nematode and other plant diseases and their associated epidemiology. It also covers the genetics of resistance and modern management on plant disease. Plant Pathology, Fifth Edition, is the most comprehensive resource and textbook that professionals, faculty and students can consult for well-organized, essential information. This thoroughly revised edition is 45% larger, covering new discoveries and developments in plant pathology and enhanced by hundreds of new color photographs and illustrations.

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Low Carbon Stabilization and Solidification of Hazardous Wastes details sustainable and low-carbon treatments for addressing environmental pollution problems, critically reviewing low-carbon stabilization/solidification technologies. This book presents the latest state-of-the-art knowledge of low-carbon stabilization/solidification technologies to provide cost-effective sustainable solutions for real-life environmental problems related to hazardous wastes including contaminated sediments. As stabilization/solidification is one of the most widely used waste remediation methods for its versatility, fast implementation and final treatment of hazardous waste treatment, it is imperative that those working in this field follow the most recent developments. Low Carbon Stabilization and Solidification of Hazardous Wastes is a necessary read for academics, postgraduates, researchers and engineers in the field of environmental science and engineering, waste management, and soil science, who need to keep up to date with the most recent advances in low-carbon technologies. This audience will develop a better understanding of these low-carbon mechanisms and advanced characterization technologies, fostering the future development of low-carbon technologies and the actualization of green and sustainable remediation.

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Adaptive Phytoremediation Practices: Resilience to Climate Change discusses current phytoremediation practices under an ever-pressing need for environmental remediation due to increasing pollution in a changing climate. Phytoremediation is increasingly relevant due to plants’ high effectiveness and sustainability during remediation and the ability of potential phytoremediation plants to adapt to changes in climate. Changing climatic conditions cause various biotic and abiotic stresses in plants and thereby negatively affect a plant’s establishment, growth, and yield. Therefore, the integration of suitable climate-resilient plants and adaptive remedial practices along with proper agro-biotechnological interventions is of paramount importance to mitigate the rapidly growing pollution. This book is an important reference for environmental scientists, particularly those working in pollution management and remediation, forming an up-to-date collection of phytoremediation practices that provide sustainable solutions as a holistic approach for carrying out phytoremediation under changing climatic conditions.

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Materials processing using explosion, shock-wave and high-strain-rate phenomena was developed after WWII, and these explosive forming and welding techniques have since been adopted as an accepted industrial technology. Such extremely high-rate phenomena historically used empirical experiences while the experimental conditions were not well documented due to the difficulties inherent in understanding the real response or behaviour of materials. Based upon the recent development of numerical techniques for analysis and the enriched data available on the behaviour of materials, it is now possible to predict such high-rate phenomena based upon numerical and experimental approaches including optical observation. Explosion, Shock-wave and High-strain-rate Phenomena of Advanced Materials demonstrates the deformation of various materials at high-rate based upon numerical analysis and supported by experimental evidence. The book is recommended for researchers and engineers who would like to learn more about the high-rate effect of materials and those who need to resolve multi-physics problems based on numerical approach. It is also ideal for researchers and engineers interested with explosive and other high-rate processing of materials.

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Fresh-Cut Fruits and Vegetables: Technologies and Mechanisms for Safety Control covers conventional and emerging technologies in one single source to help industry professionals maintain and enhance nutritional and sensorial quality of fresh-cut fruits and vegetables from a quality and safety perspective. The book provides available literature on different approaches used in fresh-cut processing to ensure safety and quality. It discusses techniques with the aim of preserving quality and safety in sometimes unpredictable environments. Sanitizers, antioxidants, texturizers, natural additives, fortificants, probiotics, edible coatings, active and intelligent packaging are all presented. Both advantages and potential consequences are included to ensure microbial safety, shelf-life stability and preservation of organoleptic and nutritional quality. Industry researchers, professionals and students will all find this resource essential to understand the feasibility and operability of these techniques in modern-day processing to make informed choices.

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Sensors for Mechatronics, Second Edition, offers an overview of the sensors and sensor systems required and applied in mechatronics. Emphasis lies on the physical background of the operating principles that is illustrated with examples of commercially available sensors and recent developments. Chapters discuss the general aspects of sensors, with a special section on quantities, notations and relations. In addition, the book includes a section devoted to sensor errors and error minimization that apply to most of the sensors discussed. Each subsequent chapter deals with one class of sensors, pursuing a classification according to physical principles rather than measurands. Categories discussed include resistive, capacitive, inductive and magnetic, optical, piezoelectric and acoustic sensors. For each category of sensors, a number of applications is given. Where appropriate, a section is added on the interfacing of the sensor.

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Animal Behavior, Third Edition covers animal behavior from its neurological underpinnings to the importance of behavior in conservation. The book's authors, Michael Breed and Janice Moore, bring almost 60 years of combined experience as university professors, much of that teaching animal behavior. Chapters cover this social behavior and the relationship between parasites, pathogens and behavior. Thoughtful coverage has also been given to foraging behavior, mating and parenting behavior, anti-predator behavior, and learning. The book addresses the physiological foundations of behavior in a way that is both accessible and inviting, with each chapter beginning with learning objectives and ending with thought-provoking questions. Additionally, special terms and definitions are highlighted throughout, making this book an essential work for students and academic seeking a foundation in the field.

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Atlas of the Developing Mouse Brain, Second Edition builds on the features of successful first edition, providing a comprehensive and convenient reference for all areas of the mouse brain at Fetal-Day 17.5 (E17.5), Day-of-Birth (P0), and Day-Six postnatal (P6). The book also delineates the parts of the eye, features of the skull, ganglia, nerves, arteries, veins, bones and foramina. This atlas is an essential tool for researchers and students who study the development of the mouse brain, or for those who interpret findings from genetic manipulation.

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Forecasting and Planning for Volcanic Hazards, Risks, and Disasters expands and complements the subject and themes in Volcanic Hazards, Risks and Disasters. Together, the two volumes represent an exhaustive compendium on volcanic hazards, risks, and disasters. Volume two presents a comprehensive picture of the volcano dynamics relevant for volcanic hazard forecasts. It also includes case studies of the associated risks and aspects like operational volcano observatory responses, communication before and across volcanic crises, emergency planning, social science aspects, and resilience from volcanic disasters. Forecasting and Planning for Volcanic Hazards, Risks, and Disasters takes a geoscientific approach to the topic while integrating the social and economic issues related to volcanoes and volcanic hazards and disasters.

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Snow Leopards: Biodiversity of the World: Conservation from Genes to Landscapes is the only comprehensive work on the biology, behavior, and conservation status of the snow leopard, a species that has long been one of the least studied, and hence poorly understood, of the large cats. Breakthroughs in technologies and methodologies to study this elusive cat have come rapidly, including non-invasive genetics, camera traps, and GPS-satellite collaring. The book begins with chapters on the genetic standing and taxonomy of the snow leopard, followed by chapters on their behavior and ecology. Additional contributions follow on the current and emerging threats to the species, which include longstanding concerns, such as poaching and conflicts with livestock, and new and emerging threats such as mining and climate change. A section on conservation solutions, backed by valuable case studies, starts with an overview of the important role mountain communities play in assuring the snow leopard’s long-term persistence. In addition, chapters on the role of captive snow leopards for the conservation of the species, state-of-the-art techniques and technologies for studying and monitoring snow leopards, status reports from around the region, and future perspectives, such as transboundary conservation initiatives, international conventions (CITES, CMS, etc.), the role of the IUCN Cat Specialist Group and the Snow Leopard Network, and undertakings such as the Global Snow Leopard Forum facilitated by the World Bank are also included.

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Detailed and concise dissection directions, updated valuable information and extraordinary illustrations make The Dissection of Vertebrates, 3rd Edition the new ideal manual for students in comparative vertebrate anatomy, as well as a superb reference for vertebrate and functional morphology, vertebrate paleontology, and advanced level vertebrate courses, such as in mammalogy, ornithology, ichthyology, and herpetology. This newly revised edition of the most comprehensive manual available continues to offer today’s more visually oriented student with a manual combining pedagogically effective text with high-quality, accurate and attractive visual references. This new edition features updated and expanded phylogenetic coverage, revisions to the illustrations and text of the lamprey, shark, perch, mudpuppy, frog, cat, pigeon, and reptile skull chapters, and new sections on amphioxus or lancelet (Branchiostoma, Cephalochodata), a sea squirt (Ciona, Urochordata), shark musculature, a gravid shark, shark embryo, cat musculature, and the sheep heart. Using the same systematic approach within a systemic framework as the first two editions, The Dissection of Vertebrates, 3rd Edition covers several animals commonly used in providing an anatomical transition sequence. Nine animals are covered: amphioxus, sea squirt, lamprey, shark, perch, mudpuppy, frog, cat, and pigeon, plus five reptile skulls, two mammal skulls, and the sheep heart.

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Protein Modificomics: From Modifications to Clinical Perspectives comprehensively deals with all of the most recent aspects of post-translational modification (PTM) of proteins, including discussions on diseases involving PTMs, such as Alzheimer’s, Huntington’s, X-linked spinal muscular atrophy-2, aneurysmal bone cyst, angelman syndrome and OFC10. The book also discusses the role PTMs play in plant physiology and the production of medicinally important primary and secondary metabolites. The understanding of PTMs in plants helps us enhance the production of these metabolites without greatly altering the genome, providing robust eukaryotic systems for the production and isolation of desired products without considerable downstream and isolation processes.

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New Approaches of Protein Function Prediction from Protein Interaction Networks contains the critical aspects of PPI network based protein function prediction, including semantically assessing the reliability of PPI data, measuring the functional similarity between proteins, dynamically selecting prediction domains, predicting functions, and establishing corresponding prediction frameworks. Functional annotation of proteins is vital to biological and clinical research and other applications due to the important roles proteins play in various biological processes. Although the functions of some proteins have been annotated via biological experiments, there are still many proteins whose functions are yet to be annotated due to the limitations of existing methods and the high cost of experiments. To overcome experimental limitations, this book helps users understand the computational approaches that have been rapidly developed for protein function prediction.

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The Encyclopedia of Marine Mammals, Third Edition covers the ecology, behavior, conservation, evolution, form and function of whales, dolphins, seals, sea lions, manatees, dugongs, otters and polar bears. This edition provides new content on anthropogenic concerns, latest information on emerging threats such as ocean noise, and impacts of climate change. With authors and editors who are world experts, this new edition is a critical resource for all who are interested in marine mammals, especially upper level undergraduate and graduate students, researchers, and managers, and is a top reference for those in related fields, from oceanographers to environmental scientists.

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Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics.

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Mathematica by Example, Sixth Edition is an essential resource for the Mathematica user, providing step-by-step instructions on achieving results from this powerful software tool. The book fully accounts for the changes to functionality and visualization capabilities and accomodates the full array of new extensions in the types of data and problems that Mathematica can immediately handle, including cloud services and systems, geographic and geometric computation, dynamic visualization, interactive applications and other improvements. It is an ideal text for scientific students, researchers, and aspiring programmers seeking further understanding of Mathematica. Written by seasoned practitioners with a view to practical implementation and problem-solving, the book's pedagogy is delivered clearly and without jargon using representative biological, physical and engineering problems. Code is provided on an ancillary website to support the use of Mathematica across diverse applications and subject areas.

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Differential Equations with Mathematica, Fifth Edition uses the fundamental concepts of the popular platform to solve (analytically, numerically, and/or graphically) differential equations of interest to students, instructors, and scientists. Mathematica’s diversity makes it particularly well suited to performing calculations encountered when solving many ordinary and partial differential equations. In some cases, Mathematica’s built-in functions can immediately solve a differential equation by providing an explicit, implicit, or numerical solution. In other cases, Mathematica can be used to perform the calculations encountered when solving a differential equation. Because one goal of elementary differential equations courses is to introduce students to basic methods and algorithms so that they gain proficiency in them, nearly every topic covered this book introduces basic commands, also including typical examples of their application. A study of differential equations relies on concepts from calculus and linear algebra, so this text also includes discussions of relevant commands useful in those areas. In many cases, seeing a solution graphically is most meaningful, so the book relies heavily on Mathematica’s outstanding graphics capabilities.

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Diagnosis and Treatment of Traumatic Brain Injury will improve readers’ understanding of the complexities of diagnosis and management of traumatic brain injuries. Featuring chapters on drug delivery, different treatments, and rehabilitation, this volume discusses in detail the impact early diagnosis and effective management has on the long-term prognosis of these injuries and the lives of those affected. This book will be relevant for neuroscientists, neurologists, clinicians, and anyone working to better understand these injuries.

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Elementary Linear Algebra, Sixth Edition provides a solid introduction to both the computational and theoretical aspects of linear algebra, covering many important real-world applications, including graph theory, circuit theory, Markov chains, elementary coding theory, least-squares polynomials and least-squares solutions for inconsistent systems, differential equations, computer graphics and quadratic forms. In addition, many computational techniques in linear algebra are presented, including iterative methods for solving linear systems, LDU Decomposition, the Power Method for finding eigenvalues, QR Decomposition, and Singular Value Decomposition and its usefulness in digital imaging.

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Applied Numerical Methods for Chemical Engineers emphasizes the derivation of a variety of numerical methods and their application to the solution of engineering problems, with special attention to problems in the chemical engineering field. These algorithms encompass linear and nonlinear algebraic equations, eigenvalue problems, finite difference methods, interpolation, differentiation and integration, ordinary differential equations, boundary value problems, partial differential equations, and linear and nonlinear regression analysis. MATLAB is adopted as the calculation environment throughout the book because of its ability to perform all the calculations in matrix form, its large library of built-in functions, its strong structural language, and its rich graphical visualization tools. Through this book, students and other users will learn about the basic features, advantages and disadvantages of various numerical methods, learn and practice many useful m-files developed for different numerical methods in addition to the MATLAB built-in solvers, develop and set up mathematical models for problems commonly encountered in chemical engineering, and solve chemical engineering related problems through examples and after-chapter problems with MATLAB by creating application m-files.

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Wetzel’s Limnology: Lake and River Ecosystems, Fourth Edition, presents a fully updated revision of the classic textbook Limnology: Lake and River Ecosystems - last published in 2001. The coverage has been thoroughly updated with recent research and theoretical developments. Each chapter of this edited volume has been written by an expert, or team of experts, providing a comprehensive and global perspective, with the editors working closely with the authors to maintain continuity within and between the chapters. This is not only an essential textbook for undergraduate and graduate students in limnology but also a standard reference book for seasoned limnologists and other scientists.

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Mitochondrial Diseases, Volume 194 presents the most common clinical manifestations, providing an up-to-date summaries on the clinical presentations, diagnostic processes, genetic counseling and treatment options in mitochondrial diseases. Contents include specialist biochemical analyses and targeted molecular genetic testing, as well as first-line genome-wide sequencing to accelerate speed of diagnosis while avoiding time-consuming, expensive and invasive investigations. Establishing a genetic diagnosis allows patients with mitochondrial diseases to have reproductive options, all of which are covered within. This book is intended for neurologists to help them recognize and manage patients with mitochondrial diseases.

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Basic Statistics with R: Reaching Decisions with Data provides an understanding of the processes at work in using data for results. Sections cover data collection and discuss exploratory analyses, including visual graphs, numerical summaries, and relationships between variables - basic probability, and statistical inference - including hypothesis testing and confidence intervals. All topics are taught using real-data drawn from various fields, including economics, biology, political science and sports. Using this wide variety of motivating examples allows students to directly connect and make statistics essential to their field of interest, rather than seeing it as a separate and ancillary knowledge area. In addition to introducing students to statistical topics using real data, the book provides a gentle introduction to coding, having the students use the statistical language and software R. Students learn to load data, calculate summary statistics, create graphs and do statistical inference using R with either Windows or Macintosh machines.

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Machine Learning: A Bayesian and Optimization Perspective, 2nd edition, gives a unified perspective on machine learning by covering both pillars of supervised learning, namely regression and classification. The book starts with the basics, including mean square, least squares and maximum likelihood methods, ridge regression, Bayesian decision theory classification, logistic regression, and decision trees. It then progresses to more recent techniques, covering sparse modelling methods, learning in reproducing kernel Hilbert spaces and support vector machines, Bayesian inference with a focus on the EM algorithm and its approximate inference variational versions, Monte Carlo methods, probabilistic graphical models focusing on Bayesian networks, hidden Markov models and particle filtering. Dimensionality reduction and latent variables modelling are also considered in depth. This palette of techniques concludes with an extended chapter on neural networks and deep learning architectures. The book also covers the fundamentals of statistical parameter estimation, Wiener and Kalman filtering, convexity and convex optimization, including a chapter on stochastic approximation and the gradient descent family of algorithms, presenting related online learning techniques as well as concepts and algorithmic versions for distributed optimization. Focusing on the physical reasoning behind the mathematics, without sacrificing rigor, all the various methods and techniques are explained in depth, supported by examples and problems, giving an invaluable resource to the student and researcher for understanding and applying machine learning concepts. Most of the chapters include typical case studies and computer exercises, both in MATLAB and Python. The chapters are written to be as self-contained as possible, making the text suitable for different courses: pattern recognition, statistical/adaptive signal processing, statistical/Bayesian learning, as well as courses on sparse modeling, deep learning, and probabilistic graphical models. New to this edition: Complete re-write of the chapter on Neural Networks and Deep Learning to reflect the latest advances since the 1st edition. The chapter, starting from the basic perceptron and feed-forward neural networks concepts, now presents an in depth treatment of deep networks, including recent optimization algorithms, batch normalization, regularization techniques such as the dropout method, convolutional neural networks, recurrent neural networks, attention mechanisms, adversarial examples and training, capsule networks and generative architectures, such as restricted Boltzman machines (RBMs), variational autoencoders and generative adversarial networks (GANs). Expanded treatment of Bayesian learning to include nonparametric Bayesian methods, with a focus on the Chinese restaurant and the Indian buffet processes.

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The Neuroscience of Depression: Genetics, Cell Biology, Neurology, Behaviour and Diet is a comprehensive reference to the aspects, features and effects of depression. This book provides readers with the behavior and psychopathological effects of depression, linking anxiety, anger and PSTD to depression. Readers are provided with a detailed outline of the genetic aspects of depression including synaptic genes and the genome-wide association studies (GWAS) of depression, followed by a thorough analysis of the neurological and imaging techniques used to study depression. This book also includes three full sections on the various effects of depression, including diet, nutrition and molecular and cellular effects. The Neuroscience of Depression: Genetics, Cell Biology, Neurology, Behaviour and Diet is the only resource for researchers and practitioners studying depression.

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Basic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, which requires a multidisciplinary team approach with input from medicinal chemists, biologists, pharmacologists, drug metabolism experts, toxicologists, clinicians, and a host of experts from numerous additional fields. Enabling technologies such as high throughput screening, structure-based drug design, molecular modeling, pharmaceutical profiling, and translational medicine are critical to the successful development of marketable therapeutics. Given the wide range of disciplines and techniques that are required for cutting edge drug discovery and development, a scientist must master their own fields as well as have a fundamental understanding of their collaborator’s fields. This book bridges the knowledge gaps that invariably lead to communication issues in a new scientist’s early career, providing a fundamental understanding of the various techniques and disciplines required for the multifaceted endeavor of drug research and development. It provides students, new industrial scientists, and academics with a basic understanding of the drug discovery and development process. The fully updated text provides an excellent overview of the process and includes chapters on important drug targets by class, in vitro screening methods, medicinal chemistry strategies in drug design, principles of in vivo pharmacokinetics and pharmacodynamics, animal models of disease states, clinical trial basics, and selected business aspects of the drug discovery process.

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Biomedical Engineering Design presents the design processes and practices used in academic and industry medical device design projects. The first two chapters are an overview of the design process, project management and working on technical teams. Further chapters follow the general order of a design sequence in biomedical engineering, from problem identification to validation and verification testing. The first seven chapters, or parts of them, can be used for first-year and sophomore design classes. The next six chapters are primarily for upper-level students and include in-depth discussions of detailed design, testing, standards, regulatory requirements and ethics. The last two chapters summarize the various activities that industry engineers might be involved in to commercialize a medical device.

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Paxinos and Franklin's The Mouse Brain in Stereotaxic Coordinates, Compact Fifth Edition, is the compact version of the most widely used and cited atlas of the mouse brain in print. It emulates in design and accuracy Paxinos and Watson’s The Rat Brain in Stereotaxic Coordinates, the most cited publication in neuroscience. The compact edition provides the coronal plates and diagrams of the full mouse atlas in a smaller, more convenient spiral format and at a student friendly price. High resolution digital photographs of the coronal plane of section from the full 5th edition complement the coronal drawings. Unique to the compact, it includes an introduction to the use of the atlas in stereotaxic surgery.

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Encyclopedia of Caves, Third Edition, provides detailed background information to anyone with a serious interest in caves. This includes students, both undergraduate and graduate, in the earth, biological and environmental sciences, and consultants, environmental scientists, land managers and government agency staff whose work requires them to know something about caves and the biota that inhabit them. Caves touch on many scientific interests in geology, climate science, biology, hydrology, archaeology, and paleontology, as well as more popular interests in sport caving and cave exploration. Case studies and descriptions of specific caves selected for their special features and public interest are also included. This book will appeal to these audiences by providing in-depth essays written by expert authors chosen for their expertise in their assigned subject.

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Malignant Pleural Mesothelioma: A Guide for Clinicians is a practical book developed to assist clinicians, pathologist and molecular biologist in the management of malignant pleural mesothelioma (MPM). MPM represents a challenge in terms of diagnosis, staging and treatment, and to date, the optimal management of MPM patients has not yet been clearly defined – and this book is intended to be an efficient tool for these cases. The book encompasses topics such as epidemiology and surveillance evidence, multimodality imaging assessment of MPM, pathology, molecular mechanisms and treatment of such disease. Additionally, it discusses the standard operative procedures and the future directions for the management of MPM from experts’ experiences. Malignant Pleural Mesothelioma: A Guide for Clinicians is a valuable source for oncologists, pathologist, cancer researchers, thoracic specialists and several members of biomedical field who needs to learn more from experts about the diagnosis, operative procedures and treatment of malignant pleural mesothelioma.

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The Autoimmune Diseases, Sixth Edition, emphasizes the "3 P’s" of 21st Century medicine: precision, prediction and prevention. Topics cover the modern systems approach to biology that involves large amounts of personalized, ongoing physiologic data ("omics") coupled with advanced methods of analysis, new tests of genetic engineering, such as CRISPR, auto inflammatory diseases, autoimmune responses to tumor immunotherapy, and information on normal immune response and disorders. Each of the major autoimmune disorders is discussed by researchers and clinical investigators experienced in dealing with patients. Chapters emphasize the immunologic basis of the disease as well as the use of immunologic diagnostic methods and treatments. The book also covers several cross-cutting issues related to the recognition and treatment of autoimmune diseases, including chapters on the measurement of autoantibodies and T cells, the use of biomarkers as early predictors of disease, and new methods of treatment.

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Veterinary Toxicology, Basic and Clinical Principles, Third Edition, is a unique, single reference that teaches the basic principles of veterinary toxicology to any student at the DVM, MS or PhD level. While comparable texts are primarily directed on the field of human toxicology, this text thoroughly prepares toxicologists and students on the newest approaches for diagnosing chemical and plant poisoning cases in animals. Many chapters on topics not covered in any previous books are provided, such as target organ toxicity, radiation and radioactive materials, FDA regulatory issues, and ethics in veterinary toxicology. Completely revised and updated to include the most recent developments in the field, including new toxins, methods and regions, this book is an essential resource for advanced students and researchers in toxicology, practicing veterinary toxicologists, poison control centers, marine biologists, environmentalists and animal scientists.

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Thorp and Covich’s Freshwater Invertebrates, Fourth Edition: Keys to Neotropical Hexapoda, Volume Three, provides a guide for identifying and evaluating a key subphylum, hexapoda, for Central America, South America and the Antarctic. This book is essential for anyone working in water quality management, conservation, ecology or related fields in this region, and is developed to be the most modern and consistent set of taxonomic keys available. It is part of a series that is designed to provide a highly comprehensive, current set of keys for a given bioregion, with all keys written in a consistent style. This series can be used for a full spectrum of interested readers, from students, to university professors and government agencies.

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Every species has to preserve the integrity of its genome to ensure faithful passage of genetic information to the progeny. At the same time, there are times during the life of the organism and population in general when a fine balance in genome stability and diversification has to be made to benefit the survival of the species. Genome Stability teaches the reader how various species maintain this fine balance in genome stability and genome diversification in response to their environments. Genome Stability covers a wide range of topics, including the genome stability of DNA/RNA viruses, prokaryotes, single cell eukaryotes, lower multicellular eukaryotes and mammals. Topics also include major DNA repair mechanisms, the role of chromatin in genome stability, human diseases associated with genome instability as well as changes in genome stability in response to aging. Finally, Genome Stability covers how epigenetic factors contribute to genome stability and how the species pass the memory of the encounters to the progeny, thus influencing the genome of the progeny in an indirect manner. This volume is an essential resource for geneticists, epigeneticists, and molecular biologists who are looking to gain a deeper understanding of this rapidly-expanding field, and can also be of great use to advanced students who are looking to gain additional expertise in genome stability.

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Boorman’s Pathology of the Rat: Reference and Atlas, Second Edition, continues its history as the most comprehensive pathology reference on rat strains for researchers across science and medicine using rat models in the laboratory. It offers readers an added emphasis on the Sprague-Dawley and Wistar rat strains that is consistent with current research across academia, government, and industry. In addition, the book provides standard diagnostic criteria, basic content on histology, histological changes that result from drug toxicity and neoplasm, pathology terminology, and four-color photographs from the NTP archive and database. With updated references and photographs, as well as coverage of all rat strains, this book is not only the standard in the field, but also an invaluable resource for toxicologists, biologists, and other scientists engaged in regulatory toxicology who must make the transition from pathology results to the promulgation of meaningful regulations.

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Volcanoes are unquestionably one of the most spectacular and awe-inspiring features of the physical world. Our paradoxical fascination with them stems from their majestic beauty and powerful, sometimes deadly, destructiveness. Notwithstanding the tremendous advances in volcanology since ancient times, some of the mystery surrounding volcanic eruptions remains today. The Encyclopedia of Volcanoes summarizes our present knowledge of volcanoes; it provides a comprehensive source of information on the causes of volcanic eruptions and both the destructive and beneficial effects. The early chapters focus on the science of volcanism (melting of source rocks, ascent of magma, eruption processes, extraterrestrial volcanism, etc.). Later chapters discuss human interface with volcanoes, including the history of volcanology, geothermal energy resources, interaction with the oceans and atmosphere, health aspects of volcanism, mitigation of volcanic disasters, post-eruption ecology, and the impact of eruptions on organismal biodiversity.

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Readers familiar with the first three editions of Ecology and Classification of North American Freshwater Invertebrates (edited by J.H. Thorp and A.P. Covich) will welcome the comprehensive revision and expansion of that trusted professional reference manual and educational textbook from a single North American tome into a developing multi-volume series covering inland water invertebrates of the world. The series entitled Thorp and Covich’s Freshwater Invertebrates (edited by J.H. Thorp) begins with the current Volume I: Ecology and General Biology (edited by J.H. Thorp and D.C. Rogers), which is designed as a companion volume for the remaining books in the series. Those following volumes provide taxonomic coverage for specific zoogeographic regions of the world, starting with Keys to Nearctic Fauna (Vol. II) and Keys to Palaearctic Fauna (Vol. III). Volume I maintains the ecological and general biological focus of the previous editions but now expands coverage globally in all chapters, includes more taxonomic groups (e.g., chapters on individual insect orders), and covers additional functional topics such as invasive species, economic impacts, and functional ecology. As in previous editions, the 4th edition of Ecology and Classification of North American Freshwater Invertebrates is designed for use by professionals in universities, government agencies, and private companies as well as by undergraduate and graduate students.

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The Atlas of Drosophila Morphology: Wild-type and Classical Mutants is the guide every Drosophila researcher wished they had when first learning genetic markers, and the tool they wish they had now as a handy reference in their lab research. Previously, scientists had only poor-quality images or sketches to work with, and then scattered resources online - but no single visual resource quickly at their fingertips when explaining markers to new members of the lab, or selecting flies to do their genetic crosses, or hybrids. This alphabetized guide to Drosophila genetic markers lays flat in the lab for easy referencing. It contains high-resolution images of flies and the appropriate marker on the left side of each page and helpful information for the marker on the facing page, such as symbol, gene name, synonyms, chromosome location, brief informative description of the morphology, and comments on marker reliability. A companion website with updated information, useful links, and additional data provided by the authors complements this extremely valuable resource.

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The previous two editions of the Human Nervous System have been the standard reference for the anatomy of the central and peripheral nervous system of the human. The work has attracted nearly 2,000 citations, demonstrating that it has a major influence in the field of neuroscience. The 3e is a complete and updated revision, with new chapters covering genes and anatomy, gene expression studies, and glia cells. The book continues to be an excellent companion to the Atlas of the Human Brain, and a common nomenclature throughout the book is enforced. Physiological data, functional concepts, and correlates to the neuroanatomy of the major model systems (rat and mouse) as well as brain function round out the new edition.

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