Search results for ""author leon v berhardt""

This edited volume contains seven chapters, each detailing recent advancements in medicine and biology. Chapter One presents an overview of drug-related problems in pediatrics. Chapter Two evaluates the role that Maytenus ilicifolia can play in the treatment of melanoma skin cancer. Chapter Three presents a review of biosensors for lipopolysaccharides and assays for studies of lipopolysaccharide binding interactions. Chapter Four presents a literature review of treatment options for carpal tunnel syndrome. Chapter Five describes the application of metabolomics, a science that quantifies and qualifies metabolites in an organism, in bio-medical research. Chapter Six presents the results of a systematic screening that was performed to identify macromolecules that are able to induce accumulation of ascitic fluid in rodents. Finally, Chapter Seven describes a study wherein the method of gravitational mass spectroscopy was used to study the long-range order in an ensemble of atomic nuclei clusters in chicken egg yolk before and after adsorption by beet sugar on the chromosomes.

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This edited volume contains six chapters that each describe recent advancements in medicine and biology. Chapter One summarizes recent discoveries regarding the immunomodulatory effects of vitamin D3 on human health with an emphasis on the interplay of transcription factors and reviews the most recent recommendations based on new clinical evidence for vitamin D3 dosages for the prevention and treatment of COVID-19. Chapter Two focuses on idiopathic membranous nephropathy, the most common cause of nephrotic syndrome in adults who do not suffer from diabetes mellitus. Chapter Three details the emerging worldwide prevalence of myopathies, their evolving diagnostic parameters, and the newer therapeutic modalities. Chapter Four includes a review of medroxyprogesterone, which is a type of progestin that is used as a long-lasting injectable contraceptive and for the treatment of hormone-dependent tumours. Chapter Five describes synovial fluid, which lubricates and cushions joints during motion, and the effects of visco-supplements on the function of synovial fluid. Lastly, Chapter Six introduces the properties of dopamine acrylamide and discusses its application potential in detail.

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This edited volume presents seven chapters detailing recent advancements in the fields of medicine and biology. Chapter One describes the regularities of abzyme production in patients with autoimmune diseases as well as in experimental mice. Chapter Two reviews the partners that assist polytopic membrane proteins in their way to acquiring their final structure. Chapter Three presents an approach for the development of an efficient biological sensor for the detection of biochemicals in large scales. Chapter Four shows the different flavin-based fluorescent proteins and fatty-acid-binding proteins and the advantages and disadvantages of using these anaerobic fluorescent proteins for real-time imaging in complex systems versus aerobic fluorescent proteins. Chapter Five discusses the main benefits of exercise for cirrhotic patients and current exercise prescription guidelines for this population. Chapter Six concerns the role thiamine deficiency plays in causing paediatric lactic acidosis. Finally, Chapter Seven discusses the mechanism of wound healing involving stem cells in IIIa burns and proposes using the state of NC1 conformations as an objective indicator of epidermal restoration and the topology of solenoid chromosome construction as an indicator of dermis restoration.

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Volume 162 opens with an assessment of the modern available data, as well as the results from the authors' own research, on the neurotropic effects of amino acid L-arginine. The effects of L-arginine and some arginine-containing oligopeptides on pain and pain-induced behavior in rats are examined. Depending on their binding to activate specific receptors, antagonists have selective functions. As such, this compilation details their specificity, mode of interactions and their usefulness and drawbacks for humans. Next, a review on how CD14 interacts with different ligands is discussed, particularly focusing on how CD14 consequently transduces the signaling to induce some relevant diseases. The authors also review some trends in the treatment of anxiety with natural compounds and transition metal-catalyzed couplings for the synthesis of new drugs with anxiolytic properties. Natural products have been widely used in the treatment of anxiety disorders and as a source of bioactive heterocyclic compounds. Methods for improving the perception and attitude of health workers towards generic drugs are proposed, such as putting forward generic drugs as one of the learning topics in college curricula, and conducting scientific discussions and conferences on generic drugs through professional organizations. The penultimate study comprehensively reviews the clinicopathological features of lipoblastomas and emphasizes the importance of accurate diagnosis and the differentiation of lipoblastomas from other histologically similar lipomatous neoplasms. The closing study proposes that the relaxant effects of flavone may be due to the inhibition of enzyme activities and intracellular Ca2+ of the trachealis after increasing these two cyclic nucleotides.

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This compilation opens with a review of the structure and life cycle of neuraminidase in influenza A, and also discusses the method of developing neuraminidase inhibitors derived from natural products and peptides. Following this, the authors describe the different uses of chlorhexidine in the medical field, focusing on dental use. Particularly, the authors discuss its: properties, chemistry, forms of presentation, substantivity and cytotoxicity; uses in dentistry: cariology, periodontology, oral surgery and endodontics. Additionally, the authors discuss rufinamide, a novel triazole derivative which differs from commercial antiepileptic drugs. It is used as an adjunctive medicine in children, adults and the elder population, and administered orally. One study discusses antiviral treatment for the avian influenza A virus using neuraminidase inhibitors such as oseltamivir and zanamivir. Although both inhibitors show therapeutic and prophylactic activities against the H5N1 strains, it is proposed that treatment should be further developed in order to increase the efficiency of the inhibitors against the strains. Angiogenesis or neovascularization is a global term which indicates the physiological process involving the sprouting of new blood vessels from the pre-existing ones. The development of new blood vessels from differentiating endothelial cells is called vasculogenesis. This collection addresses how these processes are vital for tissue development and wound healing in damaged tissues. The spectrum of spondyloarthritides with inflammatory bowel disease and enteropathic arthritis is examined in an effort to give the reader an insight into the risk factors, treatment and prognosis of this clinically challenging rheumatic disease. Later, the principles of optical coherence tomography-guided femtosecond laser cataract surgery are explored. The combination of femtosecond laser surgery and optical coherence tomography imaging simultaneously guides the development of next-generation femtosecond surgical lasers in cataract surgery and explores femtosecond-laser surgical strategies. The authors present a novel colorimetric method for the assay of XI using a reducing monosaccharide determination. The test solution was mixed with 20-fold volume of the 50 mM Na2SiO3, 600 mM Na2MoO4, and 0.95 M HCl aqueous solution (pH 4.5), in which a yellow molybdosilicate species was formed. The penultimate chapter introduces the origin, preparation, applications of Taiyi Shenzhen (Taiyi Moxa Stick Moxibustion), and reviews the relevant research in the past ten years. The concluding study focuses on the daily foraging of honeybees, which is one of the most well-organized social behaviors that exist among social insects. Honeybees are extensively used model animals in behavioral studies for understanding the time-space learning, landmark use and concept of learning.

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Advances in Medicine and Biology. Volume 150 first discusses how the emergence of multidrug resistant gram-negative bacteria, along with the lack of development of new antibiotics, led the medical community to look to polymyxins for therapeutical uses in critically ill patients. Next, the authors go on to discuss lenalidomide, a chemical analog of thalidomide and a member of the group of immunomodulatory or cereblon-binding drugs. Lenalidomide has antineoplastic, antiproliferative, antiangiogenic, anti-inflammatory, pro-erythropoieic, and immunomodulatory properties. Lenalidomide binds to a specific hydrophobic pocket in the protein cereblon. This pocket is coded by the exons 10 and 11 on the C-end of cereblon gene. Cereblon interacts with the DNA damage-binding protein-1, cullin 4, and regulator of cullins 1 to form the E3 ubiquitin ligase complex. Lenalidomide also enhances the antitumor effect of chimeric antigen receptor modified T cells in murine models of aggressive B-cell non-Hodgkin lymphoma. Lenalidomide has also been studied in the treatment of cutaneous manifestations of systemic lupus erythematosus and neurodegenerative disorders connected with neuroinflammation, such as amyotrophic lateral sclerosis. Additionally, the authors to discuss the current evidence on the use of troponin as a prognostication biomarker in neonatal encephalopathy, as well as the importance of monitoring cardiac function after hypoxic ischaemic brain damage. The basic science and clinical significance of CD180-negative plasmablasts in various autoimmune and inflammatory diseases is reviewed. In systemic and organ-specific autoimmune diseases, CD180-negative plasmablasts play crucial roles and are useful as a disease marker. Because CD180 has a complex function, the mechanism of the increase of CD180 negative B cells may be different in each disease. In closing, the concept of intensive care rehabilitation was developed with the Federal Rehabilitation Council BAR. Both early rehabilitation for neurological and neurosurgical patients and intensive care rehabilitation for patients with other critical illnesses are detailed.

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This edited volume includes eight chapters, each of which describe recent advances in medicine and biology. Chapter One discusses dietary recommendations and beneficial compounds, such as vitamin D, omega-3 fatty acids, antioxidants, and phytochemicals to aid the management of abnormal lipid metabolism in postmenopausal women. Chapter Two discusses the role of viral infection and features from the host that take part in the development of hemophagocytic lymphohistiocytosis (HLH). Chapter Three analyses the effects of caffeine and coffee consumption on airways and lung function, particularly in the case of asthma. Chapter Four describes the use of natural and herbal drugs in the treatment of hepatitis B. Chapter Five presents the results of a genetic survey for carbapenem-resistant Klebsiella pneumoniae (CRKP). Chapter Six describes the treatment of degenerative lumbar spinal stenosis using soft interspinous process device. Chapter Seven reviews the efficacy of tonsillectomy for rheumatic diseases. Finally, Chapter Eight summarises the available literature concerning graft pre-soaking in anterior cruciate ligament reconstructions as a method of reducing the likelihood of post-operative infections, which can lead to septic arthritis.

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