Search results for ""virus""

An exploration of the key aspects of life on Earth – now and in the future – through the study of 10 and a half species. 'Entertaining and intellectually stimulating... The book highlights the wonderfully interconnected nature of our fragile planet. If you want big science at an accessible scale, this is for you' BBC Wildlife If an alien visitor were to collect ten souvenir life forms to represent life on earth, which would they be? This is the thought-provoking premise of Marianne Taylor's The Story of Life in 10½ Chapters. Each life form explains a key aspect about life on Earth. From the sponge that seems to be a plant but is really an animal to the almost extinct soft-shelled turtle deemed extremely unique and therefore extremely precious, these examples reveal how life itself is arranged across time and space, and how humanity increasingly dominates that vision. Taylor, a prolific science writer, considers the chemistry of a green plant and ponders the possibility of life beyond our world. She investigates the virus in an attempt to determine what a life form is; and wonders if the human – 'a distinct and very dominant species with an inevitably biased view of life' – could evolve in a new direction. She tells us that the giraffe was one species, but is now four; that the dusky seaside sparrow may be revived through 're-evolution', or cloning; explains the significance of Darwin's finch to evolution; and much more. The 'half' species is artificial intelligence. Itself an experiment to understand and model life, AI is central to our future – although from the alien visitor's standpoint, unlikely to inherit the earth in the long run.

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Examines how the dynamics emerging from the pandemic affect our most vulnerable populations and shape a new religious landscape The COVID-19 pandemic upset virtually every facet of society and, in many cases, exposed gross inequality and dysfunction. The particular dynamics emerging from the coronavirus pandemic have been felt most intensely by America’s most vulnerable populations, who are disproportionately people of color and the working poor, the people whom the Bible refers to as “the least of these.” This book makes the case that the pandemic was not just a medical phenomenon, or an economic or social one, but also a religious one. Religious practice has been altered in profound ways. Controversies around religious freedom have been re-ignited over debates concerning whether government can restrict church services. Christian white supremacists not only defied shelter in place orders, but found new ways to propagate racist attacks, with their White Christian identity fueling their reactions to the pandemic. Some religious leaders, including those in communities of color, saw the virus as an indicator of God’s wrath, or as a divine test, and viewed altering their traditional practices to mitigate the virus’s spread as a weakening of faith. Religion, Race, and COVID-19 argues that there is a religious hierarchy in US society that puts “the least of these” last while prioritizing those who benefit most from white privilege. Yet these vulnerable populations draw on theological and religious resources to contend with these existential threats. The volume shows how social transformation occurs when faith is both formed and informed during crises, offering compelling insight into the saliency and lasting impact of religiosity within human culture.

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Examines how the dynamics emerging from the pandemic affect our most vulnerable populations and shape a new religious landscape The COVID-19 pandemic upset virtually every facet of society and, in many cases, exposed gross inequality and dysfunction. The particular dynamics emerging from the coronavirus pandemic have been felt most intensely by America’s most vulnerable populations, who are disproportionately people of color and the working poor, the people whom the Bible refers to as “the least of these.” This book makes the case that the pandemic was not just a medical phenomenon, or an economic or social one, but also a religious one. Religious practice has been altered in profound ways. Controversies around religious freedom have been re-ignited over debates concerning whether government can restrict church services. Christian white supremacists not only defied shelter in place orders, but found new ways to propagate racist attacks, with their White Christian identity fueling their reactions to the pandemic. Some religious leaders, including those in communities of color, saw the virus as an indicator of God’s wrath, or as a divine test, and viewed altering their traditional practices to mitigate the virus’s spread as a weakening of faith. Religion, Race, and COVID-19 argues that there is a religious hierarchy in US society that puts “the least of these” last while prioritizing those who benefit most from white privilege. Yet these vulnerable populations draw on theological and religious resources to contend with these existential threats. The volume shows how social transformation occurs when faith is both formed and informed during crises, offering compelling insight into the saliency and lasting impact of religiosity within human culture.

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This is a book which examines and explores the discoveries as well as the lives of twenty-five stellar scientists who have all contributed in different ways to the field that we know today as "molecular biology". The book covers a vast timeline from the last century to present day advances and concerns such as viral replication and transmission. The book examines the foundational structures of the field as well as how many scientists and basic scientific knowledge has contributed to our current understanding. Beginning with DNA (as hereditary material) and evolving into recombinant DNA and replication and somatic DNA, the book covers the way in which scientists have examined and explored these realms and some of the resultant discoveries which have led to the Nobel Prize. Nobel prize winners are not born, but they are made -- they are made from years of education, years of familial nurturance, years of mentoring by other scientists (either formally or informally) and of course by luck, chance, fate and surreptitious encounters. Some of our scientists have spent years studying the fruit fly (drosophila), fly genetics, mutations, replications, and of course, genes, gene replication, split genes and "jumping genes". For those seeking an overview of the field of molecular biology this text will provide an overview of the lives of those who have delved most deeply into these issues and those whose discoveries have resulted in the Nobel Prize. The test is certainly relevant in today's world as we encounter and challenge the dreaded ever evolving virus known as Covid-19 which seems intent on replicating, changing, evolving and challenging mankind and our scientific community.

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Carolyn Jones's vivid and life-affirming portraits capture people from all backgrounds—children and grandmothers, men and women of all races—living with HIV and AIDS. It is estimated that over one million people in the United States would test positive for the Human Immune Virus, and many others are already suffering from Acquired Immune Deficiency Syndrome. A common-and harmful-misconception holds that AIDS is an instant death sentence but, in fact, testing positive for HIV does not mean immediate illness. Carolyn Jones has collaborated with George DeSipio, Jr., and Michael Liberatore (co-founders of the project), and the seventy-three people who volunteered to pose for these photographs in an inspiring effort to change the way we think about AIDS. Jones's compelling portraits have the power to profoundly alter perceptions about this disease, and about the way we all live and die. AIDS poses challenging questions that we must each grapple with, whether healthy or not. These captivating pictures illustrate the self-confidence and wisdom of ordinary people coping with an extraordinary fate, facing their mortality, questioning their priorities, and living life to the fullest. Their energy, courage, and dignity in the face of such adversity offer a vital lesson in how to embrace life, day by day. Their faces and their stories are proof that AIDS doesn't look like anyone—it looks like, and ultimately is, all of us. Design Industries Foundation for AIDS (DIFFA) is the sole recipient of the royalties from the sale of Living Proof. For additional information regarding Living Proof and the Design Industries Foundation for AIDS, please call DIFFA: (212) 727-3100.

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Selected as a Doody’s Core Title for 2023! Practical and highly illustrated, Genital Dermatology Manual, 4th Edition, by Drs. Libby Edwards and Peter J. Lynch, helps clinicians at all levels of experience arrive at an accurate diagnosis for both common and rare genital dermatologic lesions. More than 500 full-color photographs are arranged by appearance for rapid identification, offering superb visual guidance even for conditions not previously encountered. This easy-to-use reference is ideal for any clinician who sees men and women with disorders of the external genitalia, including dermatologists, gynecologists, urologists, primary care physicians, nurse practitioners, nurse midwives, and physician assistants. Arranges core chapters by disease presentation, such as patches and plaques, papules and nodules, and ulcers Includes variable morphologies, making it easier to arrive at a correct diagnosis even when encountering an atypical appearance of a common condition—for example, herpes simplex virus infection is discussed in chapters on blisters, erosions and ulcers, and special issues of immunosuppressed patients Updates include more clinical photographs throughout; an expanded therapy section including sinus tract un-roofing, vestibulectomy, lysis of adhesions and therapy of clitoral pseudocyst and phimosis; a new chapter on patient education; and new coverage of transgender and cosmetic issues Features chapters on special issues such as symptoms (itching and pain), immunosuppression, and pediatric, psychologic, and geriatric aspects of genital conditions Offers increased information on diagnostic and therapeutic procedures, as well as patient handouts suitable for copying and distribution Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

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'An essential guide' (Dr Mark Hyman, author of Young Forever) to navigating life with the cognitive and mental health impairments that often accompany Long Covid.Early in the Covid-19 pandemic, the shocking mortality figures obscured the fact that death is not the only adverse outcome associated with the virus. Today, as many as 30 to 50 percent of Covid-19 survivors still experience symptoms long after their acute illness has passed, with problems especially prominent in the areas of cognitive and mental health. For long haulers, this struggle with Long Covid has irrevocably changed their lives. Many have lost their ability to work, attend school, or look after their children. They often feel misunderstood and dismissed by others. Their once-full lives are now filled only with doctors' appointments that seem more and more futile. In Clearing the Fog, neuropsychologist Dr. James C. Jackson offers people suffering from Long Covid and their families a roadmap to help them manage their 'new normal'. Focussing on cognitive impairment and mental health issues, he shows readers:- the ways they can manifest and disrupt - suggestions for how and when to seek professional evaluations- science-based treatment options and strategies- information on navigating health care systems and disability insurance- validation and hope as patients wrestle with their new diagnosisIn addition, Dr Jackson shares his own experience with chronic illness , relating to long haulers with vulnerability and compassion. Through moving stories, as well as hands-on guidance, Clearing the Fog will help long haulers understand their current situation while offering multiple ways to address it, make sense of it, and move through it with the goal of thriving instead of merely surviving.

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A Guardian Science Book of the Year 2022 ‘When science hits the headlines, Fiona Fox ... is at the heart of the action’ Financial Times ‘This is how to talk about science’ Justin Webb Do you remember the ‘Climategate’ email leak? Or the ‘Frankenfood’-style headlines about the perils of GM foods? What about the time the government sacked its own science advisor for challenging drug laws? Beyond the Hype takes us behind the scenes of some of the most contentious stories in science over the past two decades. From animal research and genetically modified foods to hybrid embryos and a global pandemic, it demonstrates the vital importance of scientists talking to the media – and warns of the damage to public understanding when scientists are silenced on the defining issues of our times. PRAISE FOR BEYOND THE HYPE ‘The way the media covers science stories and breakthroughs has never been more important or relevant . . . This book should be recommended reading’ Jim Al-Khalili, presenter of The Life Scientific ‘The pandemic has repeatedly shown the vital necessity for accurate reporting of science . . . Fox provides some riveting stories about the ups and downs of this continuing struggle.’ David Spiegelhalter, author of The Art of Statistics ‘Engaging, illuminating, important’ Rasmus Kleis Nielsen, Director of the Reuters Institute for the Study of Journalism ‘A vivid account of how journalists and scientists interact’ David Willetts, former Minister for Universities and Science ‘A lively insider’s account’ Times Literary Supplement ‘A candid inside account . . . [Fox] reveals how frontline science can be just as messy, complex and feudal as any political drama.’ Anjana Ahuja, co-author of Spike: The Virus Versus the People

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The Devil and Dr. Fauci is an unsparing critique of what author James Driscoll calls the "Drug Testing, Licensing, and Marketing Complex," or DTLM. Quietly dominating America's healthcare industry, the DTLM poses threats comparable in magnitude, if not in character, to those of the Military-Industrial Complex. With a satiric scalpel reminiscent of Jonathan Swift's, Driscoll eviscerates the DTLM's avatar Dr. Anthony Fauci, our age's version of the archetypal Dr. Faustus. He exposes Fauci's pivotal position in the DTLM, at whose core is the U.S. Food and Drug Administration. The FDA, Driscoll asserts, has long played Mephistopheles to Fauci's Faustus, with grave consequences for American healthcare.Dr. Driscoll's book is the first to upbraid the DTLM, FDA, and Fauci for exacerbating the Covid-19 crisis. Seeking to maximize profits from patentable vaccines, they rigorously suppressed off patent prophylaxis and treatment alternatives. This was but one of many DTLM follies that raised Covid's death toll and increased its socio-economic devastation. Other prominent follies were the mask posturing, arbitrary lockdowns, and closing of churches and schools that the DTLM and its political allies used to distract from their sacrifice of public health to their own agendas.We may never know if the Chinese deliberately released the Covid-19 virus, or if they created it. Yet the world now knows the destructive potential of gain of function technology. Similar epidemics or worse will strike us. To survive next time, we will need radical reforms in the FDA and transparency for the DTLM. But the opaque FDA bureaucracy, Driscoll concludes, is only one instance in our greater problem of deficient oversight within all of our increasingly powerful and ever less accountable federal bureaucracies.

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New York Times bestselling author. Attention Minecraft players, take an adventure right into the game you love!Can Gameknight999 survive a Minecraft journey one hundred years into the past?This adventure series is created especially for readers who love the fight of good vs. evil, magical academies like Hogwarts in the Harry Potter saga, and games like Minecraft, Terraria, and Pokemon GO.A freak thunderstorm strikes just as Gameknight999 is activating his father’s digitizer to re-enter Minecraft. Sparks flash across his vision as he is sucked into the game… and when the smoke clears, he’s arrived safely. But it doesn’t take long to realize that things in the Overworld are very different.Gameknight sees the same blocky terrain and square clouds as usual, but almost everything else has changed. His friends are nowhere to be found. His castle has disappeared and the village he calls home is missing its defenses and fortified wall. Even stranger, no one seems to know who he is.The User-that-is-not-a-user realizes he’s been accidentally sent a hundred years into the past, back to the time of the historic Great Zombie Invasion. None of his friends have even been born yet. But that might be the least of Gameknight999’s worries, because travelling back in time also means that the evil virus Herobrine, the scourge of Minecraft, is still alive…Sky Pony Press, is proud to publish a broad range of books for young readers—picture books for small children, chapter books, books for middle grade readers, and novels for young adults. Our list includes bestsellers for children who love to play Minecraft; stories told with LEGO bricks; books that teach lessons about tolerance, patience, and the environment, and much more.

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SHORTLISTED FOR THE WATERSTONES DEBUT FICTION PRIZE 2022 FINALIST FOR THE BARNES & NOBLE DISCOVER PRIZE 2022 FINALIST FOR THE URSULA LE GUIN PRIZE FOR FICTION 2022 WATERSTONES AND ESQUIRE BEST BOOKS OF 2022 ‘Haunting and luminous … An astonishing debut’ – Alan Moore, creator of Watchmen and V for Vendetta 'A powerfully moving and thought provoking read. At times sublime, strange and deeply human' Adrian Tchaikovsky, bestselling author of the Children of Time series Siberia, 2031. After a virus, unearthed from melting permafrost, unleashes a deadly plague upon humanity, those left alive are forced to adapt to a new world, and do so in myriad moving and inventive ways. Among those adjusting to this new normal are an aspiring comedian, employed by a theme park designed for terminally ill children, who falls in love with a mother trying desperately to keep her son alive; a scientist who, having failed to save his own son from the plague, gets a second chance at fatherhood when one of his test subjects — a pig — develops human speech; and a widowed painter and her teenage granddaughter who must set off on cosmic quest to locate a new home planet. A story of unshakeable hope that seamlessly crosses literary lines, How High We Go in the Dark follows a cast of intricately linked characters spanning hundreds of years as humankind endeavours to restore the delicate balance of the world. Wonderful and disquieting, dreamlike and all too possible. [How High We Go in the Dark] reaches far beyond our stars while its heart remains rooted to Earth, and reminds us that our wellbeing depends on the wellbeing of our world - Samantha Shannon, author of The Priory of the Orange Tree

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When it’s all said and done, penetration testing remains the most effective way to identify security vulnerabilities in computer networks. Conducting Network Penetration and Espionage in a Global Environment provides detailed guidance on how to perform effective penetration testing of computer networks—using free, open source, and commercially available tools, including Backtrack, Metasploit, Wireshark, Nmap, Netcat, and Nessus. It also considers exploits and other programs using Python, PERL, BASH, PHP, Ruby, and Windows PowerShell.The book taps into Bruce Middleton’s decades of experience with computer security, including penetration testing of military networks, the White House, utilities, manufacturing facilities, CIA headquarters, the Defense Information Systems Agency, and NASA. Mr. Middleton begins with a chapter on defensive measures/privacy issues and then moves on to describe a cyber-attack on one of his labs and how he responded to the attack. Next, the book explains how to research a target without directly "touching" that target. Once you’ve learned all you can, the text describes how to gather even more information using a more direct approach. From there, it covers mathematical analysis, considers target exploitation, and discusses Chinese and Syrian cyber-attacks. Providing authoritative guidance on cyberforensics, reverse engineering, and penetration testing, the book categorizes testing tools according to their use within the standard penetration testing framework. For each of the above-mentioned categories, you will find basic and advanced tools and procedures to help you identify security vulnerabilities in today’s networks. After reading this book, you will understand how to perform an organized and efficient penetration test. You will also learn techniques used to bypass anti-virus software and capture keystrokes of remote systems. Explaining how to put together your own penetration testing lab, the text concludes by describing how to utilize various iPhone apps to perform reconnaissance activities on wireless networks.

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Comprehensively explores sexually transmitted diseases, from epidemiology, causative pathogens, clinical impact, and immunology, to management strategies utilizing new strategies of genomics and next-generation diagnostic tools Sexually transmitted infections (STI) are very common worldwide. More than 20 different STIs have been identified, and about 19 million men and women are infected each year in the United States alone. This book looks at the complete picture of common STIs— how they form, evolve, and transmit, as well as how they can be treated and managed with modern techniques, medicines, and tools. Diagnostics to Pathogenomics of Sexually Transmitted Infections runs the spectrum of discussion ranging from introduction of causative pathogen, their pathogenesis to epidemiology, immunology, to anatomy and physiology of human genitalia and management strategies. The book offers in-depth chapter coverage on effect of probiotics on reproductive health; mucosal immunity in sexually transmitted infections; the role of circumcision in preventing STIs; Human Immunodeficiency Virus (HIV); genital herpes; molluscum contagiosum; genital warts; chlaymydia trachomatis; donovanosis; gonorrhoea; treponematoses; genital mycoplasms; bacterial vaginosis; vulvovaginal candidiasis; chlaymydia; scabies; chancroid, yeast infections; and more. Comprehensively compiles most of the major sexually transmitted infections Presents updated information on clinical aspects of sexually transmitted infections Examines the priorities in pathogenesis of human sexually transmitted infections and discusses new strategies of genomics and next-generation diagnostic tools used for detection of such pathogens Explores the future of rapid molecular diagnostic techniques and the challenges posed in the diagnosis of human STIs Includes bench to bedside content that will appeal to both basic and clinical researchers By offering the latest knowledge about recent advances in sexually transmitted infections in an interdisciplinary fashion, Diagnostics to Pathogenomics of Sexually Transmitted Infections is the perfect book for virologists, microbiologists, infectious disease experts, vaccinologists, biomedical researchers, clinicians, pharmacologists, and public health specialists.

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Oblivion Rouge follows the career of a young teenage villager named Oumi as she becomes embroiled in a conflict that threatens a futuristic Africa and the world itself. In the near future, a virus called the LEUP has infected half the population. The resulting war between the people of Liam, known as the infected, and the people of Galoum, known as the immune, becomes a bloody and brutal affair. When a mysterious army called the Hakkinen emerges to quell the war between the two countries, they adopt children of war to aid them. Oumi and her friends are enlisted to help find a cure and end the bloodshed. With an all-African cast, Oblivion Rouge stems from the roots of West African philosophy. It is both a brutal dystopian depiction of the future and a beautiful adventure that explores the depth of the human spirit. Oumi has made a promise to never suffer the losses and humiliation she has already seen in her young life. But with strange forces gathering against her continent, can she overcome her own insecurities to lead her people to paradise?Oblivion Rouge is rated OT for Older Teen, recommended for ages 16 and up. Saturday AM, the world’s most diverse manga-inspired comics, are now presented in a new format! Introducing Saturday AM TANKS, the new graphic novel format similar to Japanese Tankobons where we collect the global heroes and artists of Saturday AM. These handsome volumes have select color pages, revised artwork, and innovative post-credit scenes that help bring new life to our popular BIPOC, LGBTQ, and/or culturally diverse characters.Join in even more adventures with the other action-packed Saturday AM TANKS series:Apple Black, Clock Striker, Gunhild, Hammer, Henshin!, The Massively Multiplayer World of Ghosts, Saigami, Soul Beat, Titan King, Underground, and Yellow Stringer.

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Building on a solid foundation of knowledge and skills, this classic text from trusted author Mary Louise Turgeon clearly explains everything from basic immunologic mechanisms and serologic concepts to the theory behind procedures performed in the lab. This go-to resource prepares you for everything from mastering automated techniques to understanding immunoassay instrumentation and disorders of infectious and immunologic origin. Packed with learning objectives, review questions, step-by-step procedures, and case studies, this text is the key to your success in today's modern laboratory environment. Procedural protocols help you transition from immunology theory to practical aspects of the clinical lab. Case studies allow you to apply your knowledge to real-world situations and strengthen your critical thinking skills. Updated illustrations, photographs, and summary tables visually clarify key concepts and information. Full-color presentation clearly showcases diagrams and micrographs, giving you a sense of what you will encounter in the lab. Learning objectives and key terms at the beginning of each chapter provide measurable outcomes and a framework for organizing your study efforts. Review questions at the end of each chapter provide you with review and self-assessment opportunities. NEW! Highlights of Immunology chapter presents a clear, accessible, and easy-to-understand introduction to immunology that will help you grasp the complex concepts you need to understand to practice in the clinical lab. NEW! Stronger focus on molecular laboratory techniques. NEW! Ten chapters include COVID-19 related topics, including Primer on Vaccines chapter covering newer vaccine production methods focusing on DNA and RNA nucleic acids and viral vectors, and covering eight different platforms in use for vaccine research and development against SARS-CoV-2 virus. NEW! All chapters include significant updates based on reviewer feedback. NEW! Key Concepts interwoven throughout each chapter highlight important facts for more focused learning.

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Widely used by students, residents, generalists, and specialists, Netter's Infectious Diseases, 2nd Edition delivers must-know information on infectious diseases in a highly illustrated, easily accessible format. Concise visual overviews of essential topics provide a convenient, trustworthy way to review the basics of a given infectious disease or issue or to share with patients or staff. Drs. Elaine Jong and Dennis Stevens cover the wide spectrum of illness and disease in this complex field using memorable illustrations by world-renowned artist Frank H. Netter and others, offering a time-saving, authoritative look at infectious disease risk factors, clinical presentations, pathophysiology, and more. Covers major conditions and problems such as vaccine-preventable diseases, drug-resistant staph, community acquired pneumonia, surgical infections, pyelonephritis, viral hepatitis, and sexually transmitted infections-and provides updated approaches to diagnosis, treatment, prevention, and standards of care. Includes new clinical vignettes added to most chapters. Provides updated and expanded coverage of emerging infectious diseases such as multidrug resistant tuberculosis (MDR-TB), neuroangiostrongyliasis (rat lungworm disease), Ebola virus, Severe Acute Respiratory Disease (SARS), Middle East Respiratory Syndrome (MERS), Coronavirus Infectious Disease-2019 (COVID-19), and novel influenza viruses including public health concerns. Covers vector-borne diseases including malaria, yellow fever, Zika infections and congenital Zika syndrome, West Nile fever, Lyme disease, tick-borne encephalitis, and Chagas disease plus others. New chapters on travelers' diarrhea, cholera, and primary amebic meningoencephalitis debut in the section on international travel and outdoor activities. Contains memorable parasite life cycles and unforgettable parasite infection clinical vignettes. Features unparalleled illustrations by Drs. Frank H. Netter, Carlos Machado, and others, as well as radiologic images. Provides 24 printable patient education brochures in the enhanced ebook. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

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Science has taken center stage during the COVID-19 crisis; scientists named and diagnosed the virus, traced its spread, and worked together to create a vaccine in record time. But while science made the headlines, the arts and humanities were critical in people’s daily lives. As the world went into lockdown, literature, music, and media became crucial means of connection, and historians reminded us of the resonance of the past as many of us heard for the first time about the 1918 influenza pandemic. As the twindemics of COVID-19 and racial injustice, embodied in mass protests following the death of George Floyd and other police-committed violence, tore through the United States, a contested presidential race unfolded, which one candidate described as “a battle for the soul of the nation." Being Human During COVID documents the first year of the pandemic in real time, bringing together humanities scholars from the University of Michigan to address what it feels like to be human during the COVID-19 crisis. Over the course of the pandemic, the questions that occupy the humanities-about grieving and publics, the social contract and individual rights, racial formation and xenophobia, ideas of home and conceptions of gender, narrative and representations and power-have become shared life-or-death questions about how human societies work and how culture determines our collective fate. The contributors in this collection draw on scholarly expertise and lived experience to try to make sense of the unfamiliar present in works that range from traditional scholarly essays, to personal essays, to visual art projects. The resulting book is shot-through with fear and dread and frustration and prejudice, and, on a few occasions, with a thrilling sense of hope.

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'Superb... authoritative, thoughtful and terrifying in equal measure', The Secret Barrister'Astonishing. Detailed, dispassionate and definitive. An urgent warning and work of major importance', James O'Brien0n 26 March 2020, a new law appeared. In eleven pages it locked down tens of millions of people, confined us to our homes, banned socialising, closed shops, gyms, pubs, places of worship. It restricted our freedoms more than any other law in history, justified by the rapid spread of a deadly new virus.You may have expected such a law to be fiercely debated in Parliament. But it wasn't debated at all. A state of emergency was declared, meaning the law came into force the moment it was signed. The emergency was supposed to be short but lasted for 763 days, allowing ministers to bring in, by decree over 100 new laws restricting freedoms more than any in history - laws that were almost never debated, changed at a whim and increasingly confused the public. Meanwhile, behind the doors of Downing Street, officials and even the Prime Minister broke the very laws they had created.This book tells the startling story of the state of emergency that brought about an Emergency State. A wake-up call from one of the UK's leading human rights barristers, Emergency State shows us why we must never take our rights for granted.'A riveting account of how our democracy was put under threat during the Pandemic and why we must never let the Emergency State - all-powerful but ignorant and corrupt - take over again', Lady Hale, former President of the UK Supreme Court'Clear-eyed, forensic and compelling, Wagner sets out what happened during the Covid-19 pandemic - and the lessons we need to learn', Jonathan Freedland, author of The Escape Artist

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Newsweek and Bloomberg popular science and investigative journalist Bryan Walsh explores the history of extinction and offers a cutting-edge examination of existential risk, the dangerous mistakes we have yet to pay for, and concrete steps we can take to protect ourselves and future-proof our civilization.What is going to cause our extinction?How can we save ourselves and our future?End Times answers the most important questions facing humankindEnd Times is a compelling work of skilled reportage that peels back the layers of complexity around the unthinkable-and inevitable-end of humankind. From asteroids and artificial intelligence to volcanic supereruption to nuclear war, 15-year veteran science reporter and TIME editor Bryan Walsh provides a stunning panoramic view of the most catastrophic threats to the human race.In End Times, Walsh examines threats that emerge from nature and those of our own making: asteroids, supervolcanoes, nuclear war, climate change, disease pandemics, biotechnology, artificial intelligence, and extraterrestrial intelligence. Walsh details the true probability of these world-ending catastrophes, the impact on our lives were they to happen, and the best strategies for saving ourselves, all pulled from his rigorous and deeply thoughtful reporting and research.Walsh goes into the room with the men and women whose job it is to imagine the unimaginable. He includes interviews with those on the front lines of prevention, actively working to head off existential threats in biotechnology labs and government hubs. Guided by Walsh's evocative, page-turning prose, we follow scientific stars like the asteroid hunters at NASA and the disease detectives on the trail of the next killer virus.Walsh explores the danger of apocalypse in all forms. In the end, it will be the depth of our knowledge, the height of our imagination, and our sheer will to survive that will decide the future.

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Fans of Andy McNab, Orphan X and Frederick Forsyth, will love this unputdownable and action-packed debut thriller. 'BREATHLESS, COMPLEX AND SERIOUSLY HARDCORE' LEE CHILDOfficially Max McLean doesn't exist. Sniper. Spy. Assassin. His job is top secret, deadly... and often Max is the only thing keeping his country safe. Fortunately, he's bloody good at it.But Max is growing tired of unquestioned loyalty to his political masters. And when his latest job takes him deep into West African jungle, where a remote village has been quarantined after a sinister virus takes hold, it's time for answers.As the mission darkens further than he ever thought possible, Max faces a perilous, breath-taking quest for the truth, that will call into question everything that he once believed in, and leave the fate of humanity itself in his hands . . .The Break Line drips with authenticity, menace and first-hand knowledge of the frontline. Smart, unputdownable and packed with jaw-dropping plot twists, this is a thriller like no other._______________'Beautifully written and extensively researched, The Break Line is a riveting page-turner, a gruesome delight, and a study of what lies in the shadowed corners of the human heart' Gregg Hurwitz, author of Orphan X 'A thriller of an unusually classy calibre. Eloquently written, intensively researched ... Brabazon has crafted hugely gripping, thought-provoking yarn' Financial Times 'War correspondent James Brabazon brings his experience of the world's most dangerous places to this brutally compelling thriller . . .' Mail on Sunday'A taut, razor-edged thriller, packed with granular detail and authenticity' James Swallow, bestselling author of Nomad'It is insanely immersive, brilliantly blurring the lines between fiction and reality. I couldn't put it down' Tom Marcus, bestselling author of Soldier Spy

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The six stories in Consider Her Ways: And Others, the second collecton of John Wyndham's short tales, continue his exploration of the science fiction staple - what if? In the title story we are introduced to a world where all the men have been killed by a virus and women continue to survive in a strict caste system - bottom of the heap are the mothers. In others we meet the man who accidentally summons a devil and then has to find a way of getting rid of him without losing his immortal soul, as well as the woman who, thanks to an experiment in time, discovers why her lover abandoned her.'Wyndham writes strongly and has a gift for bizarre plots' Guardian'One of the few authors whose compulsive readability is a compliment to the intelligence' SpectatorJohn Wyndham Parkes Lucas Benyon Harris was born in 1903, the son of a barrister. He tried a number of careers including farming, law, commercial art and advertising, and started writing short stories, intended for sale, in 1925. From 1930 to 1939 he wrote short stories of various kinds under different names, almost exclusively for American publications, while also writing detective novels. During the war he was in the Civil Service and then the Army. In 1946 he went back to writing stories for publication in the USA and decided to try a modified form of science fiction, a form he called 'logical fantasy'. As John Wyndham he wrote The Day of the Triffids, The Kraken Wakes, The Chrysalids, The Midwich Cuckoos (filmed as Village of the Damned), The Seeds of Time, Trouble with Lichen, The Outward Urge, Consider Her Ways and Others, Web and Chocky. John Wyndham died in March 1969.

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Viruses are some of the simplest infectious agents on the planet, yet can cause severe and even life-threatening diseases in all forms of life - including humans. Despite relying on host cells in order to replicate, viruses can be capable of extremely rapid reproduction and very effective transmission from one person to another. Because of this, they have historically represented a significant proportion of the disease burden affecting humans, in addition to a number of new high profile diseases which have emerged in the last century. However, on a more positive note, the only two diseases to have ever been eradicated by mankind were both viruses, giving hope that in the future more viruses can be eliminated. Human Virology provides a vivid introduction to this fascinating field, by incorporating both the molecular and clinical aspects of the subject. The general principles and properties of viruses are covered in the first part of the text, while part two provides a survey of the different virus families and the human diseases they cause. Finally, the book concludes with some of the more practical aspects of the subject, such as immunization, antiviral chemotherapy and laboratory techniques. Throughout the text, case studies bring the subject to life by providing a unique perspective from real practicing doctors. In addition new 'hot topic' boxes have been incorporated into this edition, featuring current important areas of research. Little prior knowledge is assumed, making Human Virology the perfect text for those students new to the subject. The Online Resource Centre to accompany Human Virology features: For students: ·multiple-choice questions for self-directed learning ·Web links to online animations and videos For lecturers: ·Figures from the book in electronic format, ready to download

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'Beautifully written, passionate and moving, this is the book everyone should read about COVID-19' Kate Mosse'Hard to put down' Rachel Clarke'Gripping, humane, eye-opening and seriously tense' Ian DuntThe first book to tell the full story of the COVID-19 pandemic from a doctor on the frontline.ALL ROYALTIES FROM SALES GO TO HEROES, A CHARITY PROTECTING AND SUPPORTING HEALTHCARE WORKERS. On the 8th of February, Dr Dominic Pimenta encountered his first suspected case of coronavirus. Within a week, he began wearing a mask on the tube, and within a month, he moved over to the Intensive Care Unit to help fight the virus.From the initial whispers coming out of China and the collective hesitation to class this as a pandemic to full lockdown and the continued battle to treat whoever came through the doors, Dr Pimenta tells the heroic stories of how the entire system shifted to tackle this outbreak and how, ultimately, the staff managed to save lives.This incredible account captures the shock and surprise, the panic and power of an unprecedented time, and how, at this moment of despair, human generosity and kindness prevailed.'A startlingly personal account ... It can be described as a memoir, a thriller or a horror story, but it is really all at once' Observer'Reads like a thriller – a first-hand account of a group of individuals facing a terrible adversary – but it also moved me sometimes to tears because it communicates the humanity of the patients, as well as the NHS staff. As with all great writing, its honesty shines out' Tim Walker'An excellent book ... Moving and fascinating in equal measure' Xand van Tulleken

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The emotional First Sister trilogy comes to a sensational climax in this final installment, and is a must-read for science fiction fans everywhere.Astrid is finally free of the Sisterhood, yet her name carries notoriety. Those she's inspired call her the Unchained; those who want her voiceless once more, the Heretic. Now Astrid uses her knowledge of the Sisterhood's inner workings against them, aiding the moonborn in raids, all the while exploring the mysteries of her forgotten past.Meanwhile, The Sisterhood, thrives under the newly appointed Mother Lilian I, who's engaged in highstakes politics to rebuild the Sisterhood in her own image. The evil of the Sisterhood can't be purged with anything less than fire . . .Hiro val Akira is a rebel without an army. As protests rock the streets of Cytherea, Hiro moves in the shadows, driven by grief and vengeance, as they hunt the man responsible for all their pain: their father . . . Transformed by the Genekey virus, Luce navigates the growing schism within the Asters on Ceres. Hurting in her new body, she works to bridge two worlds seemingly intent on mutual destruction. All while mourning her fallen brother, though Lito sol Lucius's memory may ultimately live on.Yet Souji val Akira stands in judgment on them all, plotting the future for the entirety of humanity, and running out of time before war erupts between the Icarii and Geans. But can even the greatest human intellect outwit the Synthetics?Praise for Linden A. Lewis'Wonderfully imaginative and gripping'R.F. Kuang, author of The Poppy War'Ridiculously readable'April Genevieve Tucholke, author of The Boneless Mercies'A must-read'Audrey Coulthurst, author of Of Fire and Stars'As stylish as it is substantial'NPR

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BLACKWELL’SFIVE-MINUTE VETERINARYCONSULT REPTILE AND AMPHIBIAN STAY UP TO DATE ON THE BEST PRACTICES FOR TREATING COMMON DISEASES IN REPTILES AND AMPHIBIANS Blackwell’s Five-Minute Veterinary Consult: Reptile and Amphibian delivers a comprehensive exploration of the treatment of the most common diseases and disorders in reptiles and amphibians. The book is organized for quick and easy access to information, acting as an indispensable resource for veterinarians engaged in the care of chelonians, lizards, snakes, crocodilians, and amphibians. The book offers readers guidance from leading international voices in the field of reptile and amphibian care, packaged in a perfect clinical manual. Diagnostic and treatment information is laid out in a logical, stepwise fashion. Readers will also enjoy access to a companion website that provides users with printable history and physical exam forms, images that illustrate venipuncture and intravenous catheterization techniques in various amphibian and reptile groups, and images that illustrate methods of sexing reptiles. The ideal practical manual for veterinary practitioners and students seeking accessible and authoritative information on reptiles and amphibians, the book also offers: The treatment of common diseases and disorders in chelonians, including upper respiratory tract disease, cloacal prolapse, aural abscesses, and shell rot The treatment of common diseases in lizards, including hypovitaminosis A, nutritional secondary hyperparathyroidism, cryptosporidiosis, abscesses, and fungal infections The treatment of diseases affecting snakes, including dysecdysis, lower respiratory tract disease, inclusion body disease, stomatitis, and paramyxovirus A comprehensive exploration of the treatment of diseases affecting crocodilians, including West Nile virus, chlamydiosis, trauma, abscesses, and gout Blackwell’s Five-Minute Veterinary Consult: Reptile and Amphibian is an indispensable reference for veterinary practitioners, students, residents, and interns who wish to improve their understanding and care of chelonians, lizards, snakes, crocodilians, and amphibians.

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As with the much-praised prior editions, the third edition of Strelkauskas' Microbiology: A Clinical Approach remains a comprehensive introductory textbook written specifically for pre-nursing, nursing and allied health students. Clinically relevant throughout, it uses the theme of infection as its foundation, fitting closely with the 'One Health' approach that is considered increasingly central to the effective control of zoonoses and to combatting antimicrobial resistance. The third edition has been thoroughly revised and updated to reflect the latest developments, including the emergence of the SARS-CoV-2 virus and associated COVID-19 pandemic. The book is accompanied by a robust instructor ancillary package that allows educators to incorporate readily the book’s unique approach into their lectures and includes additional materials for students to supplement classroom learning and encourage and support study and self-reflection.Key Features: Student-focused, with all elements carefully designed to help students engage with and understand difficult concepts and to spark and hold interest Dedicated learning skill section introduces practical strategies for improving comprehension and retention Numerous text features further support learning and teaching, including chapter overviews, fast facts, case studies and human stories, and ‘why is this important?’ highlights A variety of question-and-answer types for self-testing and reflection to support and assess basic learning, to challenge students to integrate important concepts and ask students to apply what they have just learned to a specific clinical setting or problem All supported by a comprehensive suite of online resources including lecturer support material and, for students, interactive questions, lecture notes, MicroMovies and the BugParade The book is an excellent resource to guide and support inter-professional education in the health sciences and an ideal entry-point to the subject for anyone coming from another discipline and invaluable supplementary reading for medical, microbiology and biomedical science students.

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A powerful and urgent call to action: to improve our lives and our societies, we must demand open access to data for all. Information is power, and the time is now for digital liberation. Access Rules mounts a strong and hopeful argument for how informational tools at present in the hands of a few could instead become empowering machines for everyone. By forcing data-hoarding companies to open access to their data, we can reinvigorate both our economy and our society. Authors Viktor Mayer-Schönberger and Thomas Ramge contend that if we disrupt monopoly power and create a level playing field, digital innovations can emerge to benefit us all. Over the past twenty years, Big Tech has managed to centralize the most relevant data on their servers, as data has become the most important raw material for innovation. However, dominant oligopolists like Facebook, Amazon, and Google, in contrast with their reputation as digital pioneers, are actually slowing down innovation and progress by withholding data for the benefit of their shareholders––at the expense of customers, the economy, and society. As Access Rules compellingly argues, ultimately it is up to us to force information giants, wherever they are located, to open their treasure troves of data to others. In order for us to limit global warming, contain a virus like COVID-19, or successfully fight poverty, everyone—including citizens and scientists, start-ups and established companies, as well as the public sector and NGOs—must have access to data. When everyone has access to the informational riches of the data age, the nature of digital power will change. Information technology will find its way back to its original purpose: empowering all of us to use information so we can thrive as individuals and as societies.

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The Year That Changed Our World is the definitive, visual history of the Covid-19 Pandemic. With more than 400 photographs, this ambitious publication traces the arc of the Pandemic from China in early 2020 through to the vaccine breakthroughs of Spring 2021. Behind the relentless nature of the daily news since the events on Wuhan in early 2020 first broke, and the sense of fear and trepidation that the rapidly developing events provoked, what have we seen of the real stories of the world during the Pandemic? What can be told of how we lived through the pandemic and of the resilience, resourcefulness and sense of purpose with which we coped and adapted to the challenges we faced? How can we make sense of what we went through? The photographers of Agence France Presse are uniquely placed to be able to document the deeper, human stories of the Pandemic. Active in more than 150 countries, they have been able to capture all angles of the Covid-19 story. Organized into six chronological parts interleaved with thematic sections, including sport, animals and leisure, The Year That Changed Our World presents a comprehensive view, showing the extraordinary efforts to understand, control and cope with a previously unknown virus alongside the human stories of our lives at home: playing, caring, watching and sharing, both together and at a distance. Edited by Marielle Eudes, Director of Photography at Agence France Presse, and with an introduction by Eudes and further texts, quotes and insights from a range of contributors and public figures, The Year That Changed Our World is the definitive visual document of humankind's resilience in the face of the pandemic and the perfect way of understanding and showing to future generations the world during the time of Covid-19.With 500 illustrations in colour

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Dr. Richard Polin's Neonatology Questions and Controversies series highlights the toughest challenges facing physicians and care providers in clinical practice, offering trustworthy guidance on up-to-date diagnostic and treatment options in the field. In each volume, renowned experts address the clinical problems of greatest concern to today's practitioners, helping you handle difficult practice issues and provide optimal, evidence-based care to every patient.The thoroughly updated, full-color, 4th Edition of Neurology: Provides a clear management strategy for common and rare neonatal neurological disorders, offering guidance based on the most up-to-date understanding of underlying pathophysiology. Places emphasis on controversial areas that can entail different approaches. Features the most current clinical information throughout, including recent trials for hypoxic-ischemic encephalopathy, acute management of symptomatic seizures, and congenital viral meningoencephalitis: neonatal herpes simplex virus, congenital cytomegalovirus, congenital Zika, and COVID-19. Includes three new chapters on neurological and neurobehavioral evaluation in the neonatal period; white matter injury; and cerebellar hemorrhage in the premature infant. Highlights gaps in knowledge that should serve as a strong stimulus for future research. Utilizes a consistent chapter organization to help you find information quickly and easily, and contains numerous charts, graphs, radiographic images, and photographs throughout. Offers the most authoritative advice available from world-class neonatologists/neurologists who share their knowledge of new trends and developments in neonatal care. An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Purchase each volume individually, or get the entire 7-volume Neonatology Questions and Controversies set, which includes online access that allows you to search across all titles! Gastroenterology and Nutrition Hematology and Transfusion Medicine Neonatal Hemodynamics Infectious Disease, Immunology, and Pharmacology Renal, Fluid, and Electrolyte Disorders Neurology The Newborn Lung

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New emerging diseases, new diagnostic modalities for resource-poor settings, new vaccine schedules . all significant, recent developments in the fast-changing field of tropical medicine. Hunter's Tropical Medicine and Emerging Infectious Diseases, 10th Edition, keeps you up to date with everything from infectious diseases and environmental issues through poisoning and toxicology, animal injuries, and nutritional and micronutrient deficiencies that result from traveling to tropical or subtropical regions. This comprehensive resource provides authoritative clinical guidance, useful statistics, and chapters covering organs, skills, and services, as well as traditional pathogen-based content. You'll get a full understanding of how to recognize and treat these unique health issues, no matter how widespread or difficult to control. Includes important updates on malaria, leishmaniasis, tuberculosis and HIV, as well as coverage of Ebola, Zika virus, Chikungunya, and other emerging pathogens. Provides new vaccine schedules and information on implementation. Features five all-new chapters: Neglected Tropical Diseases: Public Health Control Programs and Mass Drug Administration; Health System and Health Care Delivery; Zika; Medical Entomology; and Vector Control - as well as 250 new images throughout. Presents the common characteristics and methods of transmission for each tropical disease, as well as the applicable diagnosis, treatment, control, and disease prevention techniques. Contains skills-based chapters such as dentistry, neonatal pediatrics and ICMI, and surgery in the tropics, and service-based chapters such as transfusion in resource-poor settings, microbiology, and imaging. Discusses maladies such as delusional parasitosis that are often seen in returning travelers, including those making international adoptions, transplant patients, medical tourists, and more. Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices.

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This book describes the work to be done in building an automated pandemic prevention and response capability for the US with international extensions and extendibility using artificial intelligence. The complexity of operational decisions, information sharing, situational awareness, and planned/ongoing actions by thousands of actors in pandemic prevention, preparedness and response is far too great for anyone to manage effectively. The deaths and economic devastation caused by COVID-19 yet again proved this fact, much like all other major disasters we have endured. There are too many organisations, too many differing plans and agendas, too many different people of varying experience in positions of responsibility, and too much information as well as critical need for optimal decisions and actions, to avoid calamity during the inevitable next pandemic. We need automated planning, information vetting/sharing and rapid action to optimize prevention and, if not prevented, response to minimize spread. Volume I laid out the case for a better approach than exists in the U.S. today, and our nation's military -- touted as the best in the world -- employs methodologies with precision and fidelity that optimise rapid decision making for human-sized enemies. It turns out these same methodologies and associated technologies work just as well with our microscopic enemies, like COVID-19. This book provides an overview of how it should be developed, implemented and evolved nationwide before the next pandemic. Seems like we finally should get our "act" together, otherwise the toll for passage of the next virus could be far higher as we remain unprepared. It will be hard and extensive work, which some have referenced the "Manhattan Project" or the Apollo Program, but the COVID-19 death count mandates we apply our best effort to prevent another pandemic disaster. We are better equipped now than ever to do so.

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A FINANCIAL TIMES, ECONOMIST, NEW YORKER AND NEW STATESMAN BOOK OF THE YEAR 2023'An indelible feat of reporting and an urgent read ... It's a privilege to read books like these' Te-Ping Chen, author of Land of Big Numbers'A powerful reminder of the ways in which China's future depends on who controls the past' Peter HesslerA documentary filmmaker who spent years uncovering a Mao-era death camp; an independent journalist who gave voice to the millions who suffered through Covid; a magazine publisher who dodges the secret police: these are some of the people who make up Sparks: China's Underground Historians and their Battle for the Future, a vital account of how some of China's most important writers, filmmakers, and artists have overcome crackdowns and censorship to challenge the Chinese Communist Party on its most sacred ground - its monopoly on history.In traditional China, dynasties rewrote history to justify their rule by proving that their predecessors were unworthy of holding power. Marxism gave this a modern gloss, describing history as an unstoppable force heading toward Communism's triumph. The Chinese Communist Party builds on these ideas to whitewash its misdeeds and justify its rule.But in recent years, critical thinkers from across the land have begun to challenge this state-led disremembering. Using digital technologies to bypass China's legendary surveillance state, their samizdat journals, guerilla media posts, and underground films document a pattern of disasters: from past famines and purges to the ethnic clashes and virus outbreaks of the present.Based on years of research in Xi Jinping's China, Sparks challenges stereotypes of a China where the state has quashed all free thought, revealing instead a country engaged in one of humanity's great struggles of memory against forgetting - a battle that will shape the China that emerges in the mid-21st century.

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Are you weary? Worn out by the bills that keep stacking, a virus that keeps raging, or a heart that keeps aching? If so, the book of Esther brings welcome news: Relief will come!To be clear, you didn't ask for this struggle. You want to get past it. You don't know how much longer you can hold up. But what if God is with you in this difficult season? When life seems off the rails, remember this truth: the minute you bow your head to pray is the moment God lifts his hand to help.Queen Esther learned this truth firsthand. When confronted with a royal decree that would annihilate her people, she had to make some tough choices. Would she remain silent in the face of this challenge, or would she speak up? Would she blend in, or would she stand out? But after Esther spent three days in prayer and fasting, God gave her the courage to speak up. God used her to save the nation. And God can do the same with you.In You Were Made for This Moment, pastor and New York Times bestselling author Max Lucado will help you: put your hope in the God of grand reversals, trusting that God will right every wrong cultivate courage for your challenging times by leaning on the God who redeems and restores discover your role in God's story by exploring how God can use your experiences and circumstances to join him in his holy work God never promised us a life without trials, but he does promise to be with us as we walk through them. Trust that he can redeem your struggles for a mighty purpose. You, friend, were made for this moment.

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Perfect for old fans and new readers alike, High Stakes delves deeper into the world of aces, jokers, and the hard-boiled men and women of the Fort Freak police precinct in a pulpy, page-turning novel of superheroics and Lovecraftian horror. Since an alien virus swept through New York City, the world has changed. Those who survived were divided. The lucky ones transformed into aces - heroes gifted with extraordinary powers. The rest became jokers, tragically mutated and cursed with terrifying abilities. These days, the hard-bitten police of Manhattan's notorious Fifth Precinct - 'Fort Freak' - specialise in a very particular kind of criminal . . .Officer Francis Black, vigilante joker Marcus 'The Infamous Black Tongue' Morgan and ace thief Mollie 'Tesseract' Steunenberg are stuck in Kazakhstan. The coldblooded Baba Yaga is forcing jokers into an illegal fighting ring, but her hidden agenda is much darker: her fighters' deaths serve to placate a vicious monster from another dimension. And when the last line of defence against this world weakens, all hell will break loose - literally. The Committee in New York sends a team of aces to investigate. One by one, each falls victim to evil forces - including the dark impulses within themselves. Only the most unlikely of heroes stands a chance of saving the world before utter chaos erupts. Edited by #1 New York Times bestselling author George R. R. Martin, High Stakes features the writing talents of Melinda M. Snodgrass, John J. Miller, David Anthony Durham, Caroline Spector, Stephen Leigh and Ian Tregillis.Now in development for TV: rights to develop Wild Cards for TV have been acquired by Universal Cable Productions, the team that brought you The Magicians and Mr. Robot, with the co-editor of Wild Cards, Melinda Snodgrass as executive producer.

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A Guardian Science Book of the Year 2022 ‘When science hits the headlines, Fiona Fox ... is at the heart of the action’ Financial Times ‘This is how to talk about science’ Justin Webb Do you remember the ‘Climategate’ email leak? Or the ‘Frankenfood’-style headlines about the perils of GM foods? What about the time the government sacked its own science advisor for challenging drug laws? Beyond the Hype takes us behind the scenes of some of the most contentious stories in science over the past two decades. From animal research and genetically modified foods to hybrid embryos and a global pandemic, it demonstrates the vital importance of scientists talking to the media – and warns of the damage to public understanding when scientists are silenced on the defining issues of our times PRAISE FOR BEYOND THE HYPE ‘The way the media covers science stories and breakthroughs has never been more important or relevant . . . This book should be recommended reading’ Jim Al-Khalili, presenter of The Life Scientific ‘The pandemic has repeatedly shown the vital necessity for accurate reporting of science . . . Fox provides some riveting stories about the ups and downs of this continuing struggle.’ David Spiegelhalter, author of The Art of Statistics ‘Engaging, illuminating, important’ Rasmus Kleis Nielsen, Director of the Reuters Institute for the Study of Journalism ‘A vivid account of how journalists and scientists interact’ David Willetts, former Minister for Universities and Science ‘A lively insider’s account’ Times Literary Supplement ‘A candid inside account . . . [Fox] reveals how frontline science can be just as messy, complex and feudal as any political drama.’ Anjana Ahuja, co-author of Spike: The Virus Versus the People

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A timely contribution to the fields of film history, visual cultures, and globalization studies, Cinematic Prophylaxis provides essential historical information about how the representation of biological contagion has affected understandings of the origins and vectors of disease. Kirsten Ostherr tracks visual representations of the contamination of bodies across a range of media, including 1940s public health films; entertainment films such as 1950s alien invasion movies and the 1995 blockbuster Outbreak; television programs in the 1980s, during the early years of the aids epidemic; and the cyber-virus plagued Internet. In so doing, she charts the changes—and the alarming continuities—in popular understandings of the connection between pathologized bodies and the global spread of disease.Ostherr presents the first in-depth analysis of the public health films produced between World War II and the 1960s that popularized the ideals of world health and taught viewers to imagine the presence of invisible contaminants all around them. She considers not only the content of specific films but also their techniques for making invisible contaminants visible. By identifying the central aesthetic strategies in films produced by the World Health Organization, the Centers for Disease Control, and other institutions, she reveals how ideas about racial impurity and sexual degeneracy underlay messages ostensibly about world health. Situating these films in relation to those that preceded and followed them, Ostherr shows how, during the postwar era, ideas about contagion were explicitly connected to the global circulation of bodies. While postwar public health films embraced the ideals of world health, they invoked a distinct and deeply anxious mode of representing the spread of disease across national borders.

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For epidemiologists, evolutionary biologists, and health-care professionals, real-time and predictive modeling of infectious disease is of growing importance. This book provides a timely and comprehensive introduction to the modeling of infectious diseases in humans and animals, focusing on recent developments as well as more traditional approaches. Matt Keeling and Pejman Rohani move from modeling with simple differential equations to more recent, complex models, where spatial structure, seasonal "forcing," or stochasticity influence the dynamics, and where computer simulation needs to be used to generate theory. In each of the eight chapters, they deal with a specific modeling approach or set of techniques designed to capture a particular biological factor. They illustrate the methodology used with examples from recent research literature on human and infectious disease modeling, showing how such techniques can be used in practice. Diseases considered include BSE, foot-and-mouth, HIV, measles, rubella, smallpox, and West Nile virus, among others. Particular attention is given throughout the book to the development of practical models, useful both as predictive tools and as a means to understand fundamental epidemiological processes. To emphasize this approach, the last chapter is dedicated to modeling and understanding the control of diseases through vaccination, quarantine, or culling. * Comprehensive, practical introduction to infectious disease modeling * Builds from simple to complex predictive models * Models and methodology fully supported by examples drawn from research literature * Practical models aid students' understanding of fundamental epidemiological processes * For many of the models presented, the authors provide accompanying programs written in Java, C, Fortran, and MATLAB * In-depth treatment of role of modeling in understanding disease control

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Mia Thermopolis knows just what to do in a crisis: Rule.During the Covid-19 pandemic, a section of the diary of Princess Mia Thermopolis of Genovia fell into the hands of Meg Cabot, the Princess’s royal biographer. As reported in media outlets such as Entertainment Weekly, The Mary Sue, Refinery 29, Bustle, and more, from March until June of 2020, sixteen entries of the princess’s diary were leaked onto Ms. Cabot’s blog, to the delight of over a million fans. In these entries, titled The Coronavirus Princess Diaries, the princess recorded her most heartfelt emotions while dealing with her husband’s quarantine after exposure to the virus; her personal (and political) battles while imposing health restrictions on her small European nation; life during lockdown (even in as idyllic a location as a palace on the Riviera); and of course, dealing with her demanding royal family, especially her grandmother.Since then, readers have been clamoring for more chapters of Mia’s coronavirus diary . . . and here they are at last: The Quarantine Princess Diaries include not only the previously released entries (now edited and updated with new content), but two hundred more pages of entirely original, never-before-seen entries, including the princess’s worries over a possible royal affair; a showdown between Mia and Grandmère over the latter’s intended nuptials; the eventual development and distribution of a groundbreaking intranasal vaccine for every citizen in Genovia; and, as always, a royally happy ending.After all we’ve been through, what could be more comforting for any lover of royal romance than snuggling up with a brand new installment of the diary of Mia Thermopolis, the princess who started it all?

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'The novel is an absorbing briefing on cyberwarfare as well as a masterclass in characterisation' SUNDAY TIMES Thriller of the MonthFrom the author of Harry's Game - A Sunday Times '100 best crime novels and thrillers since 1945' pickThere is a new cold war raging and its frontline warriors are Russian hackers - gang-members working freelance for the FSB, successor to the KGB. Massive thefts of personal information, electoral interference, catastrophic disruption of commercial and social services, banks, airlines, even whole countries disabled - this is happening now.Nicknamed 'Boot' because of his obsession with the Duke of Wellington and the battle of Waterloo, Edwin Coker is a case officer at the Vauxhall headquarters of MI6. When a young hacker falls into his hands and reveals details of a secret meeting, Boot conceives a daring plan to strike back - not with a computer virus of his own, but with a bomb that will seriously damage the Russian operation, spreading fear and distrust.Now Boot and his little team need a 'deniable' handler to deliver the explosives across the border from Estonia into Russia and bring the hacker back out. They turn to Merc, an ex-soldier fighting in Iraq, a gun-for-hire who knows how to get out of a tight spot. They hope.From the moment Merc sets out to cross the River Narva things do not go to plan and when the hacker's sister becomes involved, his mission turns from tough to near impossible. The scene is set for a classic story of pursuit and evasion and an epic battle for survival.

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A timely exploration of the impact of global change on the emergence, reemergence, and control of vector-borne and zoonotic viral infections From massively destructive "superstorms" to rapidly rising sea levels, the world media is abuzz with talk of the threats to civilization posed by global warming. But one hazard that is rarely discussed is the dramatic rise in the number and magnitude of tropical virus outbreaks among human populations. One need only consider recent developments, such as the spread of chikungunya across southern Europe and dengue in Singapore, Brazil, and the southern United States, to appreciate the seriousness of that threat. Representing a major addition to the world literature on the subject, Viral Infections and Global Change explores trends of paramount concern globally, regarding the emergence and reemergence of vector-borne and zoonotic viruses. It also provides up-to-date coverage of both the clinical aspects and basic science behind an array of specific emerging and reemerging infections, including everything from West Nile fever and Rift Valley fever to zoonotic hepatitis E and human bunyavirus. Important topics covered include: Epidemiology, molecular pathogenesis, and evolutionary mechanisms Host-pathogen interactions in an array of viral infections The impact of climate change on historical viral outbreaks The roles of socioeconomics, human behavior, and animal and human migrations The growing prevalence of drug and pesticide resistance The introduction of microbes and vectors through increased transboundary travel Spillover transmissions and the emergence of viral outbreaks Detecting and responding to threats from bioterrorism and emerging viral infections Predictive modeling for emerging viral infections Viral Infections and Global Change is an indispensable resource for research scientists, epidemiologists, and medical and veterinary students working in ecology, environmental management, climatology, neurovirology, virology, and infectious disease.

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The AIDS crisis of the 1980s looms large in recent histories of sexuality, medicine, and politics, and justly so—an unknown virus without a cure ravages an already persecuted minority, medical professionals are unprepared and sometimes unwilling to care for the sick, and a national health bureaucracy is slow to invest resources in finding a cure. Yet this widely accepted narrative, while accurate, creates the impression that the gay community lacked any capacity to address AIDS. In fact, as Katie Batza demonstrates in this path-breaking book, there was already a well-developed network of gay-health clinics in American cities when the epidemic struck, and these clinics served as the first responders to the disease. Before AIDS explores this heretofore unrecognized story, chronicling the development of a national gay health network by highlighting the origins of longstanding gay health institutions in Boston, Chicago, and Los Angeles, placing them in a larger political context, and following them into the first five years of the AIDS crisis. Like many other minority communities in the 1970s, gay men faced public health challenges that resulted as much from their political marginalization and social stigmatization as from any disease. Gay men mistrusted mainstream health institutions, fearing outing, ostracism, misdiagnosis, and the possibility that their sexuality itself would be treated as a medical condition. In response to these problems, a colorful cast of doctors and activists built a largely self-sufficient gay medical system that challenged, collaborated with, and educated mainstream health practitioners. Taking inspiration from rhetoric employed by the Black Panther, feminist, and anti-urban renewal movements, and putting government funding to new and often unintended uses, gay health activists of the 1970s changed the medical and political understandings of sexuality and health to reflect the new realities of their own sexual revolution.

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For thousands of years boys known as 'bleeders' faced an early, painful death from hemophilia. Dubbed 'the Royal Disease' because of its identification with Queen Victoria, the world's most renowned carrier, hemophilia is a genetic disease whose sufferers had little recourse until the mid-twentieth century. In the first book to chronicle the emergence and transformation of the hemophilia community, Susan Resnik sets her story within our national political landscape - where the disease is also a social, psychological, and economic experience. "Blood Saga" includes many players and domains: men with hemophilia and their families, medical personnel, science researchers, and the author herself, who was Director of Education of the National Hemophilia Foundation in the early 1980s. At that time the 'miracle treatment' of freeze-dried pooled plasma blood products enabled men with hemophilia to lead full, normal lives. Then the AIDS virus infiltrated the treatment system and over fifty percent of the hemophilia community became HIV-positive. But rather than collapsing, this community refocused its priorities, extended its reach, and helped shape blood safety policies to prevent further tragedy. The hemophilia community includes people from every socioeconomic and ethnic group, and Resnik's narrative and use of oral histories never lose touch with those affected by the disease. Her extensive informant interviewing allows much of this social history to be told by participants on all levels: parents, wives, nurses, doctors, government agency directors, health care providers, and many others. Gene insertion therapy now holds the promise of a cure for hemophilia in the near future. Scientific breakthroughs inevitably become intertwined with the industry and academic medical centers that govern the national health care system. And in that system, says Resnik, costs and safety are sometimes contending issues. She makes clear that the lessons learned in "Blood Saga" apply to all of us.

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'One of the best Stephen King novels not written by the master himself' - New York Times*******************The dark net is an online shadowland for criminals to operate anonymously, but when a demonic force begins to hack the minds of its users there is nowhere left to hide.Twelve-year-old HANNAH has been fitted with a high-tech prosthetic that restores her sight, but can't understand why she can now see shadows surrounding certain people.LELA, an emotionally shut-off, technophobic journalist stumbles onto a story nobody wants her to uncover. A story someone will kill to keep hidden.A former evangelist, MIKE, suffers demons - figurative and literal - and keeps an arsenal of weapons stored in the basement of the homeless shelter he runs.And DEREK is a hacker who believes himself a soldier, part of a cyber army dedicated to changing the world for the better.With the virus spreading throughout the net and an ancient evil threatening to break lose on the real world, it falls to these strangers to stop the rising darkness. THE DARK NET is a cracked-mirror version of the digital nightmare we already live in, a timely and wildly imaginative techno-thriller about the evil that lurks in real and virtual spaces, and the power of a united few to fight back.****************Praise for THE DARK NET'THE DARK NET is a megawatt defibrillator to the reader's heart' - Dean Koontz'An impressive, propulsive narrative velocity at work here' - Metro'THE DARK NET kicked my ass with its deft mash-up of both blackhat hacker culture and black magic. A fast, fantastic, throat-punch of a read' - Chuck Wendig, New York Times bestselling author of Blackbirds and Zer0es

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FINALIST FOR THE ORWELL PRIZE FOR POLITICAL WRITING 2022 THE TIMES BOOKS OF THE YEAR 2021 'A complex story, which Tooze tells with clarity and verve... The world is unlikely to be treated to a better account of the economics of the pandemic' The Times From the author of Crashed comes a gripping short history of how Covid-19 ravaged the global economy, and where it leaves us now When the news first began to trickle out of China about a new virus in December 2019, risk-averse financial markets were alert to its potential for disruption. Yet they could never have predicted the total economic collapse that would follow in COVID-19's wake, as stock markets fell faster and harder than at any time since 1929, currencies across the world plunged, investors panicked, and even gold was sold. In a matter of weeks, the world's economy was brought to an abrupt halt by governments trying to contain a spiralling public health catastrophe. Flights were grounded; supply chains broken; industries from tourism to oil to hospitality collapsed overnight, leaving hundreds of millions of people unemployed. Central banks responded with unprecedented interventions, just to keep their economies on life-support. For the first time since the second world war, the entire global economic system contracted. This book tells the story of that shutdown. We do not yet know how this story ends, or what new world we will find on the other side. In this fast-paced, compelling and at times shocking analysis, Adam Tooze surveys the wreckage, and looks at where we might be headed next.'A seriously impressive book, both endlessly quotable and rigorously analytical' Oliver Bullough, The Guardian

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Through eight outstanding editions, Kanski's Clinical Ophthalmology has been the classic specialty textbook, providing the perfect ophthalmology foundation for trainees and a valuable reference source for experienced practitioners. Building on the previous edition by Dr. Brad Bowling, Dr. John Salmon from Oxford University has comprehensively revised the textbook. The 9th Edition retains Dr. Kanski's highly effective format of succinct text and visually dynamic presentation, providing authoritative, focused guidance on the diagnosis and management of ophthalmic disorders. Extremely well organized and comprehensive in scope, this visually stunning book reflects the latest advances in the field, facilitating quick comprehension to enhance learning, aid exam preparation and guide clinical practice. As a general ophthalmic textbook, this is the gold standard. Uses targeted text, bulleted lists, tables, and visual aids to highlight salient points across all ophthalmology subspecialties. Includes 2,600 illustrations, including more than 1,000 new images of common and rare conditions and arrows to show the exact pathology. Features detailed updates on new therapeutic interventions for neurological disease and ocular tumours; new imaging techniques such as OCT, OCT angiography, and MRI; and new topics such as circadian rhythms, graft vs host disease and the effects of Ebola virus infection on the eye. Presents examination techniques in a new, separate chapter and contains new "tips" on key issues in every chapter. Provides up-to-date information on hot topics such as intravitreal treatment with anti-VEGF agents for macular disease, genetic advances in hereditary retinal dystrophies, the use of biological agents in the treatment of uveitis and scleritis and new surgical advances such as MIGS for glaucoma and limbal stem cell grafting. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

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The flame of rebellion burns across the solar system in this dazzling conclusion to Linden A. Lewis's stunning First Sister trilogy perfect for fans of Red Rising, The Handmaid's Tale, and The Expanse.'Wonderfully imaginative and gripping'R.F. Kuang, Sunday Times bestselling author of BabelAstrid is finally free of the Sisterhood, yet her name carries on. She's called the Unchained by those she's inspired and the Heretic by those who want her voiceless once more. Now Astrid uses knowledge of the Sisterhood's inner workings against them, aiding the moonborn in raids against abbeys and Cathedrals, all the while exploring the mysteries of her forgotten past. The Sisterhood is thriving under the newly appointed Mother Lilian I, now rebuilding the Sisterhood in her own image. But the evil of the Sisterhood can't be purged with anything less than fire.... Hiro val Akira is a rebel without an army, a Dagger without a Rapier. As protests rock the streets of Cytherea, Hiro moves in the shadows, driven by grief and vengeance, as they hunt the man responsible for all their pain: their father.... Transformed by the Genekey virus, Luce navigates the growing schism within the Asters on Ceres. Hurting in her new body, she works to bridge two worlds seemingly intent on mutual destruction. All while mourning her fallen brother, though Lito sol Lucius's memory may yet live on. Yet Souji val Akira stands in judgment on them all, plotting the future for all of humanity, and running out of time before war erupts between the Icarii and Geans. But can even the greatest human intellect outwit the Synthetics?Praise for Linden A. Lewis'Ridiculously readable'April Genevieve Tucholke, author of The Boneless Mercies'A must-read'Audrey Coulthurst, author of Of Fire and Stars'As stylish as it is substantial'NPR

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From the jungles of Indonesia to the very heart of New York City comes a plague that kills 100 percent of its victims. Medicine’s greatest nightmare, this modern black death is caused by the most virulent and uncontrollable mutant virus humanity has ever witnessed. And medicine can do nothing to stop its merciless spread.Scientist Debra Hart and her team of experts are tasked by the United Nations to stop the disease. Racing against time, they must find the cause and the cure and figure out why this deadly disease—spread by bats—is killing thousands in cities across the globe. Debra and her team will struggle to stop the disease from spreading to millions more, even if it means killing off every bat alive. But fighting to prevent her are manic animal rights’ activists who rail against species genocide, even if it means risking the deaths of human beings. And hidden behind a cloak of secrecy is a crazed academic who’ll even kill top American government officials to save one living creature.This is the nightmare scenario that Debra faces as the public becomes so terrified of bats that entire communities become vigilantes.Skyhorse Publishing, as well as our Arcade, Yucca, and Good Books imprints, are proud to publish a broad range of books for readers interested in fiction—novels, novellas, political and medical thrillers, comedy, satire, historical fiction, romance, erotic and love stories, mystery, classic literature, folklore and mythology, literary classics including Shakespeare, Dumas, Wilde, Cather, and much more. While not every title we publish becomes a New York Times bestseller or a national bestseller, we are committed to books on subjects that are sometimes overlooked and to authors whose work might not otherwise find a home.

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Paralleling the discovery of HIV and the rise of the AIDS pandemic, a flock of naysayers has dedicated itself to replacing genuine knowledge with destructive misinformation—and spreading from the fringe to the mainstream media and the think tank. Now from the editor of the journal AIDS and Behavior comes a bold exposé of the scientific and sociopolitical forces involved in this toxic evasion. Denying AIDS traces the origins of AIDS dissidents disclaimers during the earliest days of the epidemic and delves into the psychology and politics of the current denial movement in its various incarnations. Seth Kalichman focuses not on the “difficult” or doubting patient, but on organized, widespread forms of denial (including the idea that HIV itself is a myth and HIV treatments are poison) and the junk science, faulty logic, conspiracy theories, and larger forces of homophobia and racism that fuel them. The malignant results of AIDS denial can be seen in those individuals who refuse to be tested, ignore their diagnoses, or reject the treatments that could save their lives. Instead of ignoring these currents, asserts Kalichman, science has a duty to counter them. Among the topics covered: Why AIDS denialism endures, and why science must understand it. Pioneer virus HIV researcher Peter Duesberg’s role in AIDS denialism. Flawed immunological, virological, and pharmacological pseudoscience studies that are central to texts of denialism. The social conservative agenda and the politics of AIDS denial, from the courts to the White House. The impact of HIV misinformation on public health in South Africa. Fighting fiction with reality: anti-denialism and the scientific community. For anyone affected by, interested in, or working with researchers in HIV/AIDS, and public health professionals in general, the insight and vision of Denying AIDS will inspire outrage, discussion, and ultimately action. See http://denyingaids.blogspot.com/ for more information.

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