Search results for ""Elsevier Science Publishing Co Inc""

Atlas of the Developing Mouse Brain, Second Edition builds on the features of successful first edition, providing a comprehensive and convenient reference for all areas of the mouse brain at Fetal-Day 17.5 (E17.5), Day-of-Birth (P0), and Day-Six postnatal (P6). The book also delineates the parts of the eye, features of the skull, ganglia, nerves, arteries, veins, bones and foramina. This atlas is an essential tool for researchers and students who study the development of the mouse brain, or for those who interpret findings from genetic manipulation.

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Forecasting and Planning for Volcanic Hazards, Risks, and Disasters expands and complements the subject and themes in Volcanic Hazards, Risks and Disasters. Together, the two volumes represent an exhaustive compendium on volcanic hazards, risks, and disasters. Volume two presents a comprehensive picture of the volcano dynamics relevant for volcanic hazard forecasts. It also includes case studies of the associated risks and aspects like operational volcano observatory responses, communication before and across volcanic crises, emergency planning, social science aspects, and resilience from volcanic disasters. Forecasting and Planning for Volcanic Hazards, Risks, and Disasters takes a geoscientific approach to the topic while integrating the social and economic issues related to volcanoes and volcanic hazards and disasters.

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Snow Leopards: Biodiversity of the World: Conservation from Genes to Landscapes is the only comprehensive work on the biology, behavior, and conservation status of the snow leopard, a species that has long been one of the least studied, and hence poorly understood, of the large cats. Breakthroughs in technologies and methodologies to study this elusive cat have come rapidly, including non-invasive genetics, camera traps, and GPS-satellite collaring. The book begins with chapters on the genetic standing and taxonomy of the snow leopard, followed by chapters on their behavior and ecology. Additional contributions follow on the current and emerging threats to the species, which include longstanding concerns, such as poaching and conflicts with livestock, and new and emerging threats such as mining and climate change. A section on conservation solutions, backed by valuable case studies, starts with an overview of the important role mountain communities play in assuring the snow leopard’s long-term persistence. In addition, chapters on the role of captive snow leopards for the conservation of the species, state-of-the-art techniques and technologies for studying and monitoring snow leopards, status reports from around the region, and future perspectives, such as transboundary conservation initiatives, international conventions (CITES, CMS, etc.), the role of the IUCN Cat Specialist Group and the Snow Leopard Network, and undertakings such as the Global Snow Leopard Forum facilitated by the World Bank are also included.

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Detailed and concise dissection directions, updated valuable information and extraordinary illustrations make The Dissection of Vertebrates, 3rd Edition the new ideal manual for students in comparative vertebrate anatomy, as well as a superb reference for vertebrate and functional morphology, vertebrate paleontology, and advanced level vertebrate courses, such as in mammalogy, ornithology, ichthyology, and herpetology. This newly revised edition of the most comprehensive manual available continues to offer today’s more visually oriented student with a manual combining pedagogically effective text with high-quality, accurate and attractive visual references. This new edition features updated and expanded phylogenetic coverage, revisions to the illustrations and text of the lamprey, shark, perch, mudpuppy, frog, cat, pigeon, and reptile skull chapters, and new sections on amphioxus or lancelet (Branchiostoma, Cephalochodata), a sea squirt (Ciona, Urochordata), shark musculature, a gravid shark, shark embryo, cat musculature, and the sheep heart. Using the same systematic approach within a systemic framework as the first two editions, The Dissection of Vertebrates, 3rd Edition covers several animals commonly used in providing an anatomical transition sequence. Nine animals are covered: amphioxus, sea squirt, lamprey, shark, perch, mudpuppy, frog, cat, and pigeon, plus five reptile skulls, two mammal skulls, and the sheep heart.

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Protein Modificomics: From Modifications to Clinical Perspectives comprehensively deals with all of the most recent aspects of post-translational modification (PTM) of proteins, including discussions on diseases involving PTMs, such as Alzheimer’s, Huntington’s, X-linked spinal muscular atrophy-2, aneurysmal bone cyst, angelman syndrome and OFC10. The book also discusses the role PTMs play in plant physiology and the production of medicinally important primary and secondary metabolites. The understanding of PTMs in plants helps us enhance the production of these metabolites without greatly altering the genome, providing robust eukaryotic systems for the production and isolation of desired products without considerable downstream and isolation processes.

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New Approaches of Protein Function Prediction from Protein Interaction Networks contains the critical aspects of PPI network based protein function prediction, including semantically assessing the reliability of PPI data, measuring the functional similarity between proteins, dynamically selecting prediction domains, predicting functions, and establishing corresponding prediction frameworks. Functional annotation of proteins is vital to biological and clinical research and other applications due to the important roles proteins play in various biological processes. Although the functions of some proteins have been annotated via biological experiments, there are still many proteins whose functions are yet to be annotated due to the limitations of existing methods and the high cost of experiments. To overcome experimental limitations, this book helps users understand the computational approaches that have been rapidly developed for protein function prediction.

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The Encyclopedia of Marine Mammals, Third Edition covers the ecology, behavior, conservation, evolution, form and function of whales, dolphins, seals, sea lions, manatees, dugongs, otters and polar bears. This edition provides new content on anthropogenic concerns, latest information on emerging threats such as ocean noise, and impacts of climate change. With authors and editors who are world experts, this new edition is a critical resource for all who are interested in marine mammals, especially upper level undergraduate and graduate students, researchers, and managers, and is a top reference for those in related fields, from oceanographers to environmental scientists.

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Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics.

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Ready: A Clinical Approach Ready: A Clinical Approach

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Master nursing skills with this guide from the respected Perry, Potter & Ostendorf author team! The concise coverage in Nursing Interventions & Clinical Skills, 7th Edition makes it easy to learn the skills most commonly used in everyday nursing practice. Clear, step-by-step instructions cover more than 160 basic, intermediate, and advanced skills - from measuring body temperature to insertion of a peripheral intravenous device - using evidence-based concepts to improve patient safety and outcomes. A streamlined, visual approach makes the book easy to read, and an Evolve companion website enhances learning with review questions and handy checklists for each clinical skill. Coverage of more than 160 skills and interventions addresses the basic, intermediate, and advanced skills you'll use every day in practice. Safe Patient Care Alerts highlight risks or other key information to know in performing skills, so you can plan ahead at each step of nursing care. Unique! Using Evidence in Nursing Practice chapter provides the information needed to use evidence-based care to solve clinical problems. Coverage of evidence-based nursing techniques includes the concept of care bundles, structured practices that improve patient safety and outcomes, in addition to the coverage of teach-back. Delegation & Collaboration guidelines help you make decisions in whether to delegate a skill to unlicensed assistive personnel, and indicates what key information must be shared. Teach-Back step shows how to evaluate the success of patient teaching, so you can see whether the patient understands a task or topic or if additional teaching may be needed. Recording guidelines describe what should be reported and documented after performing skills, with Hand-off Reporting sections listing important patient care information to include in the handoff. Special Considerations indicate the additional risks or accommodations you may face when caring for pediatric or geriatric patients, as well as patients in home care settings. A consistent format for nursing skills makes it easier to perform skills, organized by Assessment, Planning, Implementation, and Evaluation. Media resources include skills performance checklists on the Evolve companion website and related lessons, videos, and interactive exercises on Nursing Skills Online. NEW! 2017 Infusion Nurses Society standards are included on administering IVs and on other changes in evidence-based practice. NEW Disaster Preparedness chapter focuses on caring for patients after biological, chemical, or radiation exposure. NEW! SBAR samples show how to quickly and effectively communicate a patient's condition in terms of Situation, Background, Assessment, and Recommendation. NEW! Practice Reflections sections include a clinical scenario and questions, helping you reflect on clinical and simulation experiences. NEW! Three Master Debriefs help you develop a better understanding of the "big picture" by synthesizing skill performance with overall patient care.

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A 65-year-old patient arrives at the Emergency Department with stroke symptoms that began 45 minutes ago. You are called STAT!Acute stroke management has changed dramatically in recent years. Tremendous advances have been made in acute treatments, diagnostic neuroimaging, and organized systems of care, and are enabling better outcomes for patients. Stroke has evolved from a largely untreatable condition in the acute phase to a true medical emergency that is potentially treatable—and sometimes curable. The Code Stroke emergency response refers to a coordinated team-based approach to stroke patient care that requires rapid and accurate assessment, diagnosis, and treatment in an effort to save the brain and minimize permanent damage.The Code Stroke Handbook contains the "essentials" of acute stroke to help clinicians provide best practice patient care. Designed to assist frontline physicians, nurses, paramedics, and medical learners at different levels of training, this book highlights clinical pearls and pitfalls, guideline recommendations, and other high-yield information not readily available in standard textbooks. It is filled with practical tips to prepare you for the next stroke emergency and reduce the anxiety you may feel when the Code Stroke pager rings.

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Atlas of Hybrid Imaging of the Heart, Lymph Nodes and Musculoskeletal System, Volume Three: Sectional Anatomy for PET/CT, PET/MRI and SPECT/CT provides a guide for interpreting PET and SPECT in relation to co-registered CT and/or MRI. In this atlas, exclusively dedicated to heart, lymph nodes and musculoskeletal system, nuclear physicians and radiologists cover hybrid nuclear medicine based on their own case studies. The practical structure in two-page unit offers readers a navigational tool based on anatomical districts, with labeled and explained low-dose multiplanar CT or MRI views merged with PET fusion imaging on one side and enhanced CT or MRI on the other. This new format enables the rapid identification of hybrid nuclear medicine findings which are now routine at leading medical centers. Each chapter begins with three-dimensional CT and/or MRI views of the evaluated anatomical region, bringing forward sectional tables. Clinical cases, tricks and pitfalls linked to several PET or SPECT radiopharmaceuticals help introduce the reader to peculiar molecular pathways and improve confidence in cross-sectional imaging that is vital for accurate diagnosis and treatments.

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The Temporal Lobe, Volume 187 covers the exponential growth of studies on the relationships between brain and language/cognition, many of which involved the temporal lobe. This volume summarizes research on the anatomy and function of the temporal lobe under both normal and pathological conditions. In addition, it discusses the interactions of the temporal lobe with other brain structures. The book highlights the role of the temporal lobe in language processing as well as vision, object, face recognition and processing. The book also discusses the temporal lobe's role in reading, speech and the processing of color, music, action and memory. Temporal lobe disorders, assessments and treatments are also covered, including encephalitis, Alzheimer’s, epilepsy, Korsakov’s syndrome, and more.

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Statistical Methods, Fourth Edition, is designed to introduce students to a wide-range of popular and practical statistical techniques. Requiring a minimum of advanced mathematics, it is suitable for undergraduates in statistics, or graduate students in the physical, life, and social sciences. By providing an overview of statistical reasoning, this text equips readers with the insight needed to summarize data, recognize good experimental designs, implement appropriate analyses, and arrive at sound interpretations of statistical results.

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"Venomous" Bites from "Non-Venomous" Snakes, Second Edition thoroughly examines the potential hazards associated with bites by non-front-fanged snakes (popularly, but inaccurately, called "rear-fanged snakes"). This diverse group contains approximately 80% of living snake species (approximately 2,900 species). A large proportion of these snakes were previously assigned to the family Colubridae but, as a consequence of expanding systematics investigations, have been split into multiple families and subfamilies. Many of these snakes produce venoms or oral secretions that contain toxins and other biologically active substances. A large variety of non–front-fanged snakes figure in the pet industry, yet little documented information or formal study of their potential medical importance has been published. Therefore, although the possible medical importance of many of these species has been subjected to speculation since the mid-19th century, there is a limited amount of useful descriptive information regarding the real hazard (or lack thereof) of this wide variety of snakes. The first edition of this book provided "one-stop shopping" by offering information regarding their possible toxicity and clinical relevance as well as recommendations for medical management of their bites. The second edition expands and updates the content with detailed information about the effects and medical management of bites by a broad representation of non–front-fanged species. The hypothetical venomous nature of some lizards considered as non-venomous such as the Komodo monitor or dragon and their allies, as well as the medical effects of their bites, is also examined. The dynamic taxonomy of advanced snakes is updated, and the bases for some of these fluid changes are discussed. Likewise, terminology is also updated in order to reflect the ongoing debates regarding the definition of "venom" and the balanced reinforcement of nonmedical criteria used to define the biological basis of the term "venomous."

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Fundamentals of Pediatric Imaging, Third Edition presents the foremost techniques of pediatric medical image analysis and processing. It includes advanced imaging techniques, neuro applications, and highlights basic anatomy needed to understand this complex specialty. The book introduces the theory and concepts of pediatric digital image analysis and newly revised information on quality and safety topics, imaging modalities, imaging applications, and new discoveries in diseases and treatments. The newly revised edition provides updates in areas of expertise including neurologic, musculoskeletal, cardiac, chest, and GU imaging. Edited by Lane F. Donnelly, MD, recipient of the Society of Pediatric Radiology’s 2009 Singleton-Taybi Award, this book is sure to be a prime reference in pediatric medical imagining.

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The Atlas of the Human Hypothalamus presents for the first time a detailed view of the cyto- and myeloarchitecture of the human hypothalamus. Providing high-resolution images of consecutive coronal sections, this book illustrates the brain area that is responsible for maintaining the homeostasis of the body by direct neuronal projections as well as by linking the central nervous system to the endocrine system. The primary goal of this atlas is to provide detailed morphological understanding of the hypothalamic structures that control numerous vital functions as well as to provide a tool to target hypothalamic areas during deep brain stimulation.

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Programming for Electrical Engineers: MATLAB and Spice introduces beginning engineering students to programming in Matlab and Spice through engaged, problem-based learning and dedicated electrical and computer engineering content. The book draws its problems and examples specifically from electrical and computer engineering, covering such topics as circuit analysis, signal processing, and filter design. It teaches relevant computational techniques in the context of solving common problems in electrical and computer engineering, including mesh and nodal analysis, Fourier transforms, and phasor analysis. Programming for Electrical Engineers: MATLAB and Spice is unique among MATLAB textbooks for its dual focus on introductory-level learning and discipline-specific content in electrical and computer engineering. No other textbook on the market currently targets this audience with the same attention to discipline-specific content and engaged learning practices. Although it is primarily an introduction to programming in MATLAB, the book also has a chapter on circuit simulation using Spice, and it includes materials required by ABET Accreditation reviews, such as information on ethics, professional development, and lifelong learning.

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Brain and Crime, Volume 197 reviews the relation between brain function and aggressive and rule-breaking (criminal) behavior. The book's focus is on the violation of social rules and not on violation of regulations that are different in different counties. It discusses the development of this behavior from childhood into adulthood, along with the mechanisms associated with the risk for aggression and rule-breaking behavior. In addition, it explores from a behavioral level concepts like psychopathology, syndrome and concepts from law, such as crime, defendant and offender. Finally, sections explore brain function, including emotion, cognitive processes, and decision-making. From the perspective of brain structure, the book covers brain networks and brain disorders. In genetics, the book includes the influence of genes and the mechanisms of epigenetics. All chapters are intended to provide information for use in the diagnosis and treatment of disorders, and in assessment and prevention.

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Engineering Design, Planning and Management, Second Edition represents a compilation of essential resources, methods, materials and knowledge developed by the author and used over two decades. The book covers engineering design methodology through an interdisciplinary approach, with concise discussions and a visual format. It explores project management and creative design in the context of both established companies and entrepreneurial start-ups. Readers will discover the usefulness of the design process model through practical examples and applications from across engineering disciplines. Sections explain useful design techniques, including concept mapping and weighted decision matrices that are supported with extensive graphics, flowcharts and accompanying interactive templates. Discussions are organized around 12 chapters dealing with topics such design concepts and embodiments, decision-making, finance, budgets, purchasing, bidding, communication, meetings and presentations, reliability and system design, manufacturing design and mechanical design.

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The Human Hypothalamus: Neuroendocrine Disorders, Volume 181 in the Handbook of Clinical Neurology series, provides comprehensive summaries of recent research on the brain and nervous system as they relate to clinical neurology. This volume summarizes the role of the hypothalamus in neuroendocrine disorders, identifying the mechanism of action, disorder etiology, and best practices for assessment and treatment. Disorders covered include pituitary hypothalamic disorders of development and growth, hypothalamic tumor related disorders, hypothalamic autoimmune disorders and infection, disorders of vasopressin, water and sodium homeostasis, eating disorders, and gonadotropic hormone regulation disorders.

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The Neurobiology, Physiology and Psychology of Pain focuses on bettering readers’ understanding of acute and chronic pain. Featuring chapters on neurotransmitters, pharmacology, and brain imaging, this volume discusses, in detail, the mechanisms of pain and experimental studies undertaken to better understand the pathways involved. The translational work in this area has applicability for neurologists, anesthesiologists, pharmacologists, and anyone working in the intersection of these areas. This volume is integral for anyone interested in the molecular underpinnings of pain at every level.

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Zika Virus Biology, Transmission, and Pathways: The Neuroscience of Zika, Volume One provides a detailed introduction to the molecular biology of the Zika virus and its features, transmission, and impact on neurological systems. Designed to better readers’ understanding of the Zika virus, this volume features chapters on the immune response, molecular mechanisms, and other areas to better understand underlying pathways. This book has applicability for neuroscientists, neurologists, virologists and anyone working to better understand the evolution and pathogenesis of Zika virus-related conditions.

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Treatments, Mechanisms, and Adverse Reactions of Anesthetics and Analgesics is an essential read for anyone working in pain management. The book addresses the onset of pain, the cause of the pain, and the administration of analgesia or anesthesia. The etiology of pain is complex and multi-factorial, which is made more complex with the use of analgesics and local or general anesthetics. This volume works to clarify all of the subjects pertinent to anesthesia and the brain, from their variety, modes of action, and adverse effects.

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Introduction to Robust Estimating and Hypothesis Testing, Fifth Edition is a useful ‘how-to’ on the application of robust methods utilizing easy-to-use software. This trusted resource provides an overview of modern robust methods, including improved techniques for dealing with outliers, skewed distribution curvature, and heteroscedasticity that can provide substantial gains in power. Coverage includes techniques for comparing groups and measuring effect size, current methods for comparing quantiles, and expanded regression methods for both parametric and nonparametric techniques. The practical importance of these varied methods is illustrated using data from real world studies. Over 1700 R functions are included to support comprehension and practice.

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The Handbook of Clinical Neurology series volumes provide comprehensive summaries of recent research on the brain and nervous system as they relate to clinical neurology. Cardiac disorders and diseases may often co-occur with, or cause, subsequent neurological disorders. Heart and Neurologic Disease identifies the top cardiac diseases and disorders most likely to have neurological disorders, how they will present, and how they are best treated. It identifies the mechanisms of action explaining why the conditions co-occur, and what clinicians should look for symptom wise, and how risk may be assessed. Coverage includes genetic cardiac disorders, cardiac trauma, surgery, infection, disease, and arrhythmia.

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Sturkie's Avian Physiology, Seventh Edition is the classic comprehensive single volume on the physiology of domestic as well as wild birds. This latest edition is thoroughly revised and updated and features several new chapters with entirely new content on such topics as vision, sensory taste, pain reception, evolution, and domestication. Chapters throughout have been greatly expanded due to the many recent advances in the field. This book is written by international experts in different aspects of avian physiology. For easy reading and searches, this book is structured under a series of themes, beginning with genomic studies, sensory biology and nervous systems, and major organs. The chapters then move on to investigate metabolism, endocrine physiology, reproduction, and finally cross-cutting themes such as stress and rhythms. New chapters on feathers and skin are featured as well. Sturkie’s Avian Physiology, Seventh Edition is an important resource for ornithologists, poultry scientists, and other researchers in avian studies. It is also useful for students in avian or poultry physiology, as well as avian veterinarians.

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Introduction to Forestry and Natural Resources, Second Edition, presents a broad, completely updated overview of the profession of forestry. The book details several key fields within forestry, including forest management, economics, policy, utilization and forestry careers. Chapters deal specifically with forest regions of the world, landowners, forest products, wildlife habitats, tree anatomy and physiology, and forest disturbances and health. These topics are ideal for undergraduate introductory courses and include numerous examples and questions for students to ponder. There is also a section dedicated to forestry careers. Unlike other introductory forestry texts, which focus largely on forest ecology rather than practical forestry concepts, this book encompasses the economic, ecological and social aspects, thus providing a uniquely balanced text. The wide range of experience of the contributing authors equips them especially well to identify missing content from other texts in the area and address topics currently covered in corresponding college courses.

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Diagnosis, Management and Modeling of Neurodevelopmental Disorders: The Neuroscience of Development is a comprehensive reference on the diagnosis and management of neurodevelopment and associated disorders. The book discusses the mechanisms underlying neurological development and provides readers with a detailed introduction to the neural connections and complexities in biological circuitries, as well as the interactions between genetics, epigenetics and other micro-environmental processes. In addition, the book also examines the pharmacological and non-pharmacological interventions of development-related conditions.

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Factors Affecting Neurological Aging: Genetics, Neurology, Behavior, and Diet is a comprehensive reference on the genetic and behavioral features associated with neurological aging and associated disorders. This book discusses the mechanisms underlying neurological aging and provides readers with a detailed introduction to the aging of neural connections and complexities in biological circuitries, as well as the physiological, behavioral, molecular, and cellular features of neurological aging. Finally, this comprehensive resource examines the use of animal modeling of aging and neurological disease.

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Atlas of Deformed and Metamorphosed Rocks from Proterozoic Orogens is a richly illustrated reference book featuring over 660 full-color field images of a range of lithologies from some Proterozoic terrains that were subjected to multiple events of magmatism, deformation, metamorphism, and metasomatism. The Atlas focuses on amphibolite to granulite facies lithologies and associated ma?c-ultrama?c rocks from Proterozoic orogens of India, Sri Lanka, Botswana, South Africa, East Antarctica, and Western Australia. Each chapter in the book begins with a brief review of geology, including deformation and metamorphic history, along with a regional geological map to help readers to visualize the ?eld observations in the relevant geological context. Each image is accompanied by a concise description providing location, lithology, structural fabric, possible deformational history, metamorphic features, partial melting, metasomatism, and other important crustal processes. This Atlas is an important source of information for a broad range of earth scientists, graduate and undergraduate students, researchers, academicians, and other professionals. This book will form a great treasure to those geoscientists who never had an opportunity to visit any of the Proterozoic orogenic belts.

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The Neuroscience of Depression: Features, Diagnosis and Treatment, is a comprehensive reference to the diagnosis and treatment of depression. This book provides readers with the mechanisms of depression reflecting on the interplay between depression and the biological and psychosocial processes. A detailed introduction to various episodes of depression, from PTSD to post-partum depression is provided, followed by a thorough discussion on biomarkers in depression and how to diagnose depression including the Hamilton Depression Rating scale. This book also includes three full sections on treatment options for depression, including pharmacological, behavioral and other novel regimes. The Neuroscience of Depression: Features, Diagnosis and Treatment is the only resource for researchers and practitioners studying, diagnosis and treating of depression.

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This atlas – and its accompanying text - is the most comprehensive work on avian neuroanatomy available so far. It identifies more than 900 hundred structures (versus ca. 250 in previous avian atlases), 180 of them for the first time. It correlates avian and mammalian neuroanatomy on the basis of homologies and applies mammalian terms to homologous avian structures. This is the first atlas that represents the fundamental histogenetic domains of the vertebrate neuroaxis on the basis of sound fate-mapping and gene expression data. This results in a substantial increase in accuracy of delineations. Developmental molecular biologists will find it easier to extrapolate early neural tube patterns into mature structures. The modern trend to shift avian neuroanatomical nomenclature toward mammalian terminology by reference to postulated homologies has been expanded to the entire brain, but is not yet complete. This creates a new standard for comparative cross-reference, which can also be applied to reptilian-mammalian comparisons.

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Genetics, Neurology, Behavior, and Diet in Parkinson's Disease: The Neuroscience of Parkinson’s Disease, Volume 2 provides a single source of material covering different scientific domains of neuropathology underlying this condition. The book covers a wide range of subjects and unravels the complex relationships between genetics, molecular biology, pharmaceutical chemistry, neurobiology, imaging, assessments, and treatment regimens. It fills a much-needed gap as a "one-stop" synopsis of everything to do with the neurology and neuroscience related to Parkinson’s disease—from chemicals and cells to individuals. It is an invaluable resource for neuroscientists, neurologists, and anyone in the field.

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Statistics in Medicine, Fourth Edition, helps medical and biomedical investigators design and answer questions about analyzing and interpreting data and predicting the sample size required to achieve useful results. It makes medical statistics easy for the non-biostatistician by outlining common methods used in 90% of medical research. The text covers how to plan studies from conception to publication, what to do with data, and follows with step-by-step instructions for biostatistical methods from the simplest levels, to more sophisticated methods now used in medical articles. Examples from almost every medical specialty, and from dentistry, nursing, pharmacy and health care management are provided. This book does not require background knowledge of statistics or mathematics beyond high school algebra and provides abundant clinical examples and exercises to reinforce concepts. It is a valuable source for biomedical researchers, healthcare providers and anyone who conducts research or quality improvement projects.

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Platelets, Fourth Edition, integrates the entire field of platelet biology, pathophysiology, and clinical medicine with contributions from 142 world experts from 18 countries. This award-winning reference provides clear presentations by basic scientists on the cellular, molecular, and genetic mechanisms of platelets and the role of platelets in thrombosis, hemorrhage, inflammation, antimicrobial host defense, wound healing, angiogenesis and cancer. It also provides start-of-the-art presentations by hematologists, cardiologists, stroke physicians, blood bankers, pathologists and other clinicians on platelet function testing, disorders of platelet numbers and function, antiplatelet therapy and therapy to increase platelet numbers and/or function. Since the publication of the Third Edition of Platelets, there has been a rapid expansion of knowledge in both basic biology of platelets and the clinical approach to platelet-related diseases. This Fourth Edition of Platelets draws all this information into a single, comprehensive and authoritative resource.

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Paxinos and Ashwell's Atlas of the Developing Rat Nervous System, Fourth Edition, builds on the many excellent features of previous editions that have made this book the most cited atlas of the developing rat brain. It provides the most comprehensive depiction of not only the structures in the brain and spinal cord, but also of the peripheral nervous system and target organs that are important for developmental neurobiologists, allowing the user to follow neural structures through the developing embryo in both time and space. The nomenclature and identification of structures in this edition have been thoroughly updated to ensure accuracy and compatibility.

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