Search results for ""Author Carmen Gil""

For human health, leishmaniasis is among the most important protozoan diseases, superseded only by malaria. Globally, 10 to 12 million people are infected with 1.5 million new cases every year. The development of cheaper new drugs is urgently needed for this neglected disease that is developing resistance to current treatments. Chemotherapy remains the only treatment option for the bulk of patients. However, this is largely unaffordable for most. In the past three years numerous advances in drug discovery have been made for treating this disease by exploiting diverging metabolic pathways between the Leishmania enzymes and their hosts, using nanotechnology to target the immune cell phagolysosomes where Leishmania resides. Drug Discovery for Leishmaniasis aims to provide a perspective of the current treatments and their challenges, blended with the emerging strategies and methodologies that will drive new target appraisals and drug developments, as well as addressing the molecular basis of resistance in Leishmania. Recent studies have shown that leishmaniasis affects some of the poorest people in the world, with 95% of fatal cases occurring in only 6 countries. With the WHO goal of eliminating this public health problem in the South-east Asia Region by 2020, this book will be important for anyone who is interested in neglected tropical diseases.

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Mr. Yes could do a lot of different, funny things…but he’d never learned how to say no. Even though it made him unhappy, he would reluctantly agree to do things because he would say yes even though he really wanted to say no One day, the unexpected happened and Mr. Yes found a powerful, new voice.So what about you? Have you ever smiled and said yes when what you really wanted to say was no? This is a fun story for readers of all ages about the importance of communication and being assertive.Guided Reading Level: P , Lexile Level: 620L Don't miss thel booktrailer! Read the first pages:

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Also available in Spanish as AlegriaJoy, the elf, has gone missing from Mateo's life. The Ragdoll Witch has cast a spell to immediately grant each one of Mateo's wishes so that Joy is no longer needed. How will Mateo ever find Joy again?

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Premiado con Medalla de Oro en Estados Unidos en los 2017 Moonbeam Children's Book AwardsMargarito era un burro muy popular en la granja, aunque con los años iba perdiendo agilidad, fortaleza y oído. Hasta que un día llegó Flamante, un hermoso potro lleno de juventud y energía. Una entrañable historia sobre el valor de la experiencia y la sabiduría que puede aportarnos el paso del tiempo. Una historia sobre el poder de la esperanza y el lenguaje universal de la música.Lexile Level: 620LNo se pierdan el booktrailer! Las primeras páginas:

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The Sparkling Elves loved the Things in the Air, those things that nobody can see, but which are there all the same. With their brightly colored clothes and their bright, gleaming smiles, they'd spend the whole day fluttering around, looking for flying surprises. And when they found them, the elves held them tightly until the Things tickled them inside. But one day, the Snouty Witches appeared, gray and gloomy, to take the Things away! Las cosas del aire is a tale that will fill your air with surprises and fill your child's face with a huge smile that no one will be able to wipe off -- not even the Snouty Witches! Lexile Level 900L

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The Sparkling Elves loved the Things in the Air, those things that nobody can see, but which are there all the same. With their brightly colored clothes and their bright, gleaming smiles, they'd spend the whole day fluttering around, looking for flying surprises. And when they found them, the elves held them tightly until the Things tickled them inside. But one day, the Snouty Witches appeared, gray and gloomy, to take the Things away! The Things in the Air is a tale that will fill your air with surprises and fill your child's face with a huge smile that no one will be able to wipe off -- not even the Snouty Witches! Lexile Level 1040L Guided Reading Level M

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Andrea's mom doesn't understand how an old box full of holes can be of any use, but her daughter is just over the moon about her latest acquisition--and rightly so! When she takes off the lid, the little girl pulls out holes in all shapes and sizes that lead her to discover remarkable characters who fill her room with amazing stories. The Box of Holes is a bewitching tale that shows us how our imaginations can fill in many gaps in our lives, bringing smiles to our faces that we should never, ever give up as lost. Lexile Level 900L Guided Reading Level M

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One morning, a purple dragon flies in through Kibo's window. In fright, the little boy runs off to some truly extraordinary places, but when he returns home and looks in the mirror, the dragon is still there -- and he's right behind him! This time, though, he's a little more purple and a little bigger than the last time Kibo saw him. Maybe if he keeps running away Kibo will be able to escape the dragon! But what if that doesn't work? How will he finally defeat such a terrible monster? Kibo and the Purple Dragon is an entertaining tale that thelps children face up to and overcome their fears. Lexile Level 920L Guided Reading Level M

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