Search results for ""springer nature switzerland""

This book guides through the fascinating world of viruses and makes readers enjoy science in an accessible way. Virologist and author Professor Van Wilson imparts knowledge about what viruses are, how they work, and how much they impact life on Earth. The book equips the reader with the scientific basics behind virus function and presents the historic milestones of virus research and discovery. Well-known viruses such as HIV or Influenza are tackled alongside novel pathogens like coronavirus SARS-CoV-2. Professor Wilson explores where they come from and how they impact our society. Last but not least the book provides exciting insights into how our immune system reacts to different viruses and how vaccines contribute to conquer pandemics. While scientifically informative, this book makes the field of virology understandable to a lay audience and encourages readers to further thinking. And more importantly, it conveys the wonder, beauty, and mystery of these ubiquitous, microscopic marvels. This book addresses anyone interested in understanding the principles of virology, viral diseases, or the impact of viruses on human societies.

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This book presents synthesis, characterization, and applications of macroporous, mesoporous, nanoporous, hierarchical porous, porous metals, and porous ceramics. Special emphasis is given to the preparation of porous activated carbon materials and porous ionic liquid-derived materials for CO2 emissions mitigation. Additionally, a chapter includes the physical and mathematical modeling in porous media. Many analytical techniques for characterization are discussed in this book. Also, the biomedical and industrial applications of porous materials in adsorption, catalysis, biosensors, drug delivery, nanotechnology are described. The content helps solving fundamental and applied problems in porous materials with length scales varying from macro- to nano-level.

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The book focuses on pharmacological and non-pharmacological approaches of psychiatric syndromes that commonly occur in patients with kidney disease. It specifically reviews principles of psychotherapy and psychopharmacology with an emphasis on organ impairment and drug-drug interactions specific to nephrology. This book also covers issues with medication nonadherence in patients with chronic kidney disease and psychiatric comorbidity, as well as the associated issues in dialysis and renal transplantation. Additionally, chapters cover various other topics addressing an active stance towards health promotion in chronically ill patients, including the critical role of the diet and physical activity. Such advice is often complex and changing depending on the stage of chronic kidney disease and the individual needs of the patient. Written by specialists in the field, Psychonephrology: A Guide to Principles and Practice serves as a valuable reference and teaching tool that provides an opportunity for learning across a rapidly evolving medical field.

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Renal Cancer: Current Status and Innovations provides a useful guide to the fundamental basics and latest diagnostic and treatment techniques for Renal Cancer. It features clearly structured and easy-to-understand chapters enabling the reader to develop a thorough understanding of screening, surveillance, diagnostics, pathology, robotic and open surgical approaches, ablation, medical treatment, psychology, and future innovations. The book provides a valuable resource for the full spectrum of clinicians involved in the multidisciplinary management of Renal Cancer.

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The book provides a framework for diagnosis and treatment of the complex facial deformities found in craniofacial microsomia and Treacher Collins syndrome. These conditions are difficult to treat due to their complexity and variable presentation. The deformities may be mild or severe and merely cosmetic to life-threatening in nature. These conditions often manifest as complex facial deformities that require multiple surgical interventions. Timing is critical when treating these patients and knowing and choosing the correct operation is key to successful outcomes. This work provides a comprehensive approach in treating these complex patient populations, seeking to answer the following questions: When to operate versus when to wait? If operating is required what operation should be performed? What is the best orthodontic approach to the associated dental deformities that develop with these conditions? How should sleep apnea be evaluated and treated in this population? What is the best management for feeding patients with these conditions? Written by experts in the field, Craniofacial Microsomia and Treacher Collins Syndrome: Comprehensive Treatment of Associated Facial Deformities aims to provide the reader with literature based best practices in treating these children from the NICU through childhood and into adulthood.

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This book presents multidimensional knowledge on children of incarcerated parents using Bronfenbrenner’s ecological theory as an organizing framework. It examines the extent to which different levels of the environment are supportive (i.e., leading to resilience) and stress-producing (i.e., contributing to risk). The volume explores four levels of the environment – microsystem, mesosystem, exosystem, and macrosystem – with specific theories and paradigms woven into the inquiry at each. At the level of child and family, it discusses the factors that influence resilience and risk in children from gestation through young adulthood; at the community level, it addresses risk and resilience in the interactions between children and families and the various systems with which they interact (e.g., child welfare). Key areas of coverage include: · A description of the factors that influence the quality of programming for children and their families. · A critical analysis of state and national policies that affect which individuals receive, or fail to receive, specific services. · An overview and evaluation of the state of knowledge and implications for research and practice to improve outcomes for children of incarcerated parents. · An organizing framework to help researchers identify gaps in the existing knowledge base and distills and organizes evidence-based information for practitioners. Children of Incarcerated Parents is an essential resource for researchers, professors, and graduate students as well as practitioners, therapists, and other professionals in child and school psychology, family studies, public health, and all interrelated disciplines, including developmental psychology, criminal justice, social work, educational policy and politics.

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The topics in this book cover a broad range of research interests: from business engineering and its application in corporate and business networking contexts to design science research as well as applied topics, where those research methods have been employed for modeling, data warehousing, information systems management, enterprise architecture management, management of large and complex projects, and enterprise transformation. The book is a Festschrift for Robert Winter in order to appreciate his work and to honor him as a personality with a high reputation in the information systems community. To this end, many professional colleagues or long-time companions both from the Institute of Information Management at the University of St. Gallen as well as from the international research community dedicated articles on topics related to Robert’s research. They reflect his ambition to uncompromisingly conduct high-class research that fuels the research community and at the same time contributes to improved industrial practice. The book is organized in three major parts: Part I “Business Engineering and Beyond” focuses on the methodology strongly shaped by Robert in St. Gallen with a focus on research being applied in corporate contexts. Part II “Design Science Research” spans from reflections on the practice of design science research to perspectives on design science research methodologies and eventually up to considerations to teach design science research methodology. Part III “Applied Fields” combines various applications of design science and related research methodologies with practical problems and future research topics.

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Now in a revised and expanded third edition, this case-based guide emphasizes the latest investigative advances in both imaging and molecular diagnostics and new treatment approaches for a wide variety of common and complex endocrine conditions. Utilizing unique clinical case histories, each main endocrine condition and disorder is curated by a senior Section Editor with an introduction to his or her area covering both physiology and pathophysiology. This introductory chapter is followed by a number of case histories written by invited experts and designed to cover the important relevant pathophysiology, following a consistent chapter format for ease of use, including bulleted objectives, case presentations, review of the diagnosis, lessons learned, and 3-5 multiple-choice review questions. Section headings include the pituitary, thyroid (overactivity, underactivity and cancer) and parathyroid, adrenal disorders, metabolic bone disease, type 2 diabetes, lipid abnormalities, obesity, and pregnancy. Topics new to this edition include PCOS, transgender medicine and the endocrine effects of viral infections.With a focus on covering major parts of the APDEM curriculum, A Case-Based Guide to Clinical Endocrinology remains a tremendous resource for junior and veteran clinicians alike.

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Building on the success of the previous edition, this review book includes all of the original content plus several new chapters dedicated to the education and implementation of transthoracic echocardiography and point-of-care ultrasonography. Chapters feature board review-style questions and answers to assist readers with board exam preparation. This book also includes the most up-to-date echocardiography content and practice guidelines. This book fills an educational gap in the perioperative and critical care echocardiography landscape. It addresses essential perioperative and critical care echocardiography topics in an accessible manner for those who provide acute care and resuscitation in any environment, including the operating room, intensive care unit, and the emergency department. Essential Echocardiography, 2nd edition, is expertly written for the practitioner with limited knowledge of echocardiography preparing for either the Examination of Special Competence in Basic Perioperative TEE (Basic PTEeXAM) or the Examination of Special Competence in Critical Care Echocardiography (CCEeXAM).

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This book makes a strong case for the inclusion of Indigenous Elders’ cultural knowledge in the delivery of inclusive education for learners who are members of minority communities. It is relevant to curriculum developers, teachers, policy makers and institutions that engage in the education of Black, Indigenous, Latinx and other minority students. This book provides opportunities for exploring the decolonization of educational approaches. It promotes the synthesis of multiple types of knowledge and ways of knowing by making a case for the incorporation of Indigenous knowledges and Indigenous Elders as teachers in learning spaces. The book is of interest to educators, students, and researchers of Indigenous knowledge and decolonizing education. Additionally, it is important for educational policy makers, especially those engaged in looking for strategic solutions to bridging educational disparities and gaps for Indigenous, Black, Latinx and other minority learners.

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This book provides a long overdue conceptual framework for integrating evidence-based principles of school psychology leadership across NASP (National Association of School Psychologists) domains of practice. It explicates the myriad ways in which school psychologists can and should serve as leaders across the NASP domains, examines the leadership role of school psychologists within each NASP domain, and presents both historical and contemporary contexts of the domains of practice. Key areas of coverage include: Concrete examples of school psychologists as leaders in the field. Spearheading initiatives and service delivery models involving consultation and collaboration. Academic intervention planning. Behavioral and mental health services. Crisis intervention and prevention. Consultation, program evaluation, and ethics of professional practice. The book offers a cogent framework for practitioners and trainers of school psychologists to further integrate principles of leadership into their work in the field. The volume culminates with a discussion of the role of school psychologists as advocates for the practice through legislative and social justice policy.Principles of Leadership in School Psychology is an essential resource for researchers, professors, and graduate students as well as professionals in school and clinical child psychology, educational policy and practice, and social work as well as all interrelated disciplines.

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The expanding remit of policing as a fundamental part of the public health continuum is increasingly acknowledged on the international scene. Similarly the growing role of health professionals as brokers of public safety means that the need for scholarly resources for developing knowledge and broadening theoretical positioning and questioning is becoming urgent and crucial. The fields of law enforcement and public health are beginning to understand the inextricable links between public safety and public health and the need to shift policies and practices towards more integrated practices. This book comes as a first, an utterly timely scholarly collection that brings together the views of multidisciplinary commentators on a wide range of issues and disciplines within the law enforcement and public health (LEPH) arena. The book addresses the more conceptual aspects of the relationship as well as more applied fields of collaboration, and the authors describe and analyze a range of service delivery examples taken from real-life instances of partnerships in action. Among the topics covered: ​Defund, Dismantle or Define Law Enforcement, Public Health, and Vulnerability Law Enforcement and Mental Health: The Missing Middle The Challenges of Sustaining Partnerships and the Diversification of Cultures Using Public Health Concepts and Metrics to Guide Policing Strategy and Practice Policing Pandemics Law Enforcement and Public Health: Partners for Community Safety and Wellbeing is essential reading for a wide array of professions and areas of expertise in the intersectoral field of LEPH. It is an indispensable resource for public health and law enforcement specialists (practitioners, educators, scholars, and researchers) and training programs across the world, as well as individuals interested in developing their knowledge and capacity to respond to complex LEPH issues in the field, including public prosecutors, coroners, and the judiciary. The text also can be used for undergraduate and postgraduate university policing, criminology, sociology, psychology, social work, public health, and medicine programs.

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This book challenges the perception of the psychiatric chart as a neutral and objective text. The chapters included in this book coalesce to reveal the psychiatric chart as a text that is, in fact, “storied” by institutional ideology that reflects, reinforces, reinterprets, and, at times, resists gendered, raced, sexualized, and classed norms, values, and presuppositions. Intersectional analysis highlights the nuanced ways in which dominant ideologies are activated in chart documentation to produce qualitatively specific psychiatric narratives of distress and related responses in the psychiatric institution. The book serves as a much-needed resource for mental health professionals, education and training programs, and researchers that meaningfully takes into account the social and structural materiality of people’s lives and its impact on experiences of distress. It will also appeal to scholars investigating equity in health care across the fields of Critical Psychology, Disability Studies, Social Work, Allied Health, Mad Studies and Social Justice.

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This book gathers a collection of cases with challenging diagnoses, in which nuclear medicine examinations have been particularly helpful in terms of the final diagnosis or follow-up. The cases presented chiefly involve patients with neurodegenerative disorders, epilepsy and brain tumors. The book is intended for nuclear medicine specialists as well as clinicians, offering essential guidance on the interpretation of neurology cases in the clinical setting, particularly with regard to correctly interpreting diagnostic imaging procedures. The authors were selected from the members of the Neuroimaging Committee of the EANM and have extensive experience as clinicians and teachers within the Nuclear Medicine Community.

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Redoing Gender demonstrates how difficult it is to be anything other than a man or a woman in a society that selectively acknowledges those two genders. Gender nonbinary people—who identify as other genders besides simply “man” or “woman”—have begun to disrupt this binary system, but the limited progress they have made has required significant everyday labor. Through interviews with 47 nonbinary people, this book offers rich description of these forms of labor, including “rethinking sex and gender,” “resignifying gender,” “redoing relationships,” and “resisting erasure.” The final chapter interrogates the lasting impact of this labor through follow-up interviews with participants four years later. Although nonbinary people are finally managing to achieve some recognition, it is clear that this change has not happened without a fight that continues to this day. The diverse experiences of nonbinary people in this book will help cisgender people relate to gender minorities with more compassion, and may also appeal to those questioning their own gender. This text will also be of keen interest to academics across Sociology and Gender Studies.

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This open access book provides researchers and professionals with a foundational understanding of online privacy as well as insight into the socio-technical privacy issues that are most pertinent to modern information systems, covering several modern topics (e.g., privacy in social media, IoT) and underexplored areas (e.g., privacy accessibility, privacy for vulnerable populations, cross-cultural privacy). The book is structured in four parts, which follow after an introduction to privacy on both a technical and social level: Privacy Theory and Methods covers a range of theoretical lenses through which one can view the concept of privacy. The chapters in this part relate to modern privacy phenomena, thus emphasizing its relevance to our digital, networked lives. Next, Domains covers a number of areas in which privacy concerns and implications are particularly salient, including among others social media, healthcare, smart cities, wearable IT, and trackers. The Audiences section then highlights audiences that have traditionally been ignored when creating privacy-preserving experiences: people from other (non-Western) cultures, people with accessibility needs, adolescents, and people who are underrepresented in terms of their race, class, gender or sexual identity, religion or some combination. Finally, the chapters in Moving Forward outline approaches to privacy that move beyond one-size-fits-all solutions, explore ethical considerations, and describe the regulatory landscape that governs privacy through laws and policies. Perhaps even more so than the other chapters in this book, these chapters are forward-looking by using current personalized, ethical and legal approaches as a starting point for re-conceptualizations of privacy to serve the modern technological landscape. The book’s primary goal is to inform IT students, researchers, and professionals about both the fundamentals of online privacy and the issues that are most pertinent to modern information systems. Lecturers or teachers can assign (parts of) the book for a “professional issues” course. IT professionals may select chapters covering domains and audiences relevant to their field of work, as well as the Moving Forward chapters that cover ethical and legal aspects. Academics who are interested in studying privacy or privacy-related topics will find a broad introduction in both technical and social aspects.

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The ideas presented in this book are a conceptual leverage to correct the rigidity of top-down practices and bring the real city, or the city of everyday life, closer to the city of conventional planning. Considering self-organization as the starting point at the base of complex systems, this book tries to understand how specific qualities emerge and evolve from this behavior. For this, the book discusses new ways of looking at and understanding cities by applying holistic methods and approaches based on the conceptual grounds of quantum, fractal, and complexity theories. The book highlights the fact that the information on how to transform and build a city is contained within the city itself. In this regard, some methodological steps to unpack complexities and translate the essential qualities of space into potential generators for city design and planning are provided. The book urges courageous experimentation and proposes a methodology where the computational nature of urban phenomena goes along with historic anthropological ideas, thus emphasizing the characteristics of a specific reality in a model. They do not exclude each other; in fact, they are part of the unbroken web of wholeness. Importantly, the proposed methodology supports gradual and natural coevolution process in the city through combining planned and unplanned actions and the involving multiplicity of actors, impacting on Urban Planning and Design Practice.

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This book presents the general objective of the REV2021 conference which is to contribute and discuss fundamentals, applications, and experiences in the field of Online and Remote Engineering, Virtual Instrumentation, and other related new technologies like Cross Reality, Data Science & Big Data, Internet of Things & Industrial Internet of Things, Industry 4.0, Cyber Security, and M2M & Smart Objects. Nowadays, online technologies are the core of most fields of engineering and the whole society and are inseparably connected, for example, with Internet of Things, Industry 4.0 & Industrial Internet of Things, Cloud Technologies, Data Science, Cross & Mixed Reality, Remote Working Environments, Online & Biomedical Engineering, to name only a few.Since the first REV conference in 2004, we tried to focus on the upcoming use of the Internet for engineering tasks and the opportunities as well as challenges around it. In a globally connected world, the interest in online collaboration, teleworking, remote services, and other digital working environments is rapidly increasing. Another objective of the conference is to discuss guidelines and new concepts for engineering education in higher and vocational education institutions, including emerging technologies in learning, MOOCs & MOOLs, and Open Resources.REV2021 on "Online Engineering and Society 4.0" was the 17th in a series of annual events concerning the area of Remote Engineering and Virtual Instrumentation. It has been organized in cooperation with the International Engineering and Technology Institute (IETI) as an online event from February 24 to 26, 2021.

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This textbook covers the main tools and techniques used in bioanalysis, provides an overview of their principles, and offers several examples of their application and future trends in diagnosis.Chapters from expert contributors explore the role of bioanalysis in different areas such as biochemistry, physiology, forensics, and clinical diagnosis, including topics from sampling/sample preparation, chemometrics in bioanalysis to the latest techniques used in the field. Particular attention is given to the recent advances in the application of mass spectrometry, NMR, electrochemical methods and separation techniques in bioanalysis. Readers will also find more about the application of microchip-based devices and analytical microarrays. This textbook will appeal to graduate/advanced undergraduate students in Chemistry, Biology, Biochemistry, Pharmacy, and Chemical Engineering. It is also a useful resource for researchers and professionals working in the fields of biomedicine and veterinary sciences, with clear explanations and examples of how the different bioanalytical devices are applied for clinical diagnosis.

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This book is an enthusiastic account of Pierre Laszlo’s life and pioneering work on catalysis of organic reactions by modified clays, and his reflections on doing science from the 1960s to 1990s. In this autobiography, readers will discover a first-hand testimony of the chemical revolution in the second half of the 20th century, and the author’s perspective on finding a calling in science and chemistry, as well as his own experience on doing science, teaching science and managing a scientific career.During this period, Pierre Laszlo led an academic laboratory and worked also in three different countries: the US, Belgium and France, where he had the opportunity to meet remarkable colleagues. In this book, he recalls his encounters and collaborations with important scientists, who shaped the nature of chemistry at times of increased pace of change, and collates a portrait of the worldwide scientific community at that time. In addition, the author tells us about the turns and twists of his own life, and how he ended up focusing his research on clay based chemistry, where clay minerals were turned in his lab to catalysis of key chemical transformations. Given its breath, the book offers a genuine information on the life and career of a chemist, and it will appeal not only to scientists and students, but also to historians of science and to the general reader.

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Business education and executive development has been one of the most fascinating industries in the world and the fastest growing segment of higher education over the past decades. Today, it is experiencing change on a scale unprecedented since the foundation of the first business schools in the early 20th Century, both due to changes in the corporate environment and also due to the impact of the COVID-19 pandemic across all industries. In this context how do you create world-class educational and training institutions that can cope with those challenges, and be rigorous, vocationally relevant and suited to the corporate growing needs in this new fluid world? And how do you combine the very best of traditional academic values with new learning technologies to create an educational model that is fit to compete in the global economy, threatened today by populism, nationalism and economic turmoil? Yet, as daunting as it is, some institutions have already made significant progress in the journey. In this book Santiago Iñiguez de Onzoño, President of IE University, and Peter Lorange, former President of IMD, bring together contributions from leading figures from some of the world’s major universities. They share their experiences in addressing some of the challenges that the industry faces today, such as diversity and inclusion, employability, the role of AI and the advent of innovative new platforms. Packed with case studies of successful initiatives in business education and executive training, this is a truly visionary book. Authors anticipate future trends and share their in-depth knowledge of what it takes to build world-class educational providers – and their vision of higher education in the future.

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This book is intended to serve as a basic introduction to scientific computing by treating problems from various areas of physics - mechanics, optics, acoustics, and statistical reasoning in the context of the evaluation of measurements. After working through these examples, students are able to independently work on physical problems that they encounter during their studies. For every exercise, the author introduces the physical problem together with a data structure that serves as an interface to programming in Excel and Python. When a solution is achieved in one application, it can easily be translated into the other one and presumably any other platform for scientific computing. This is possible because the basic techniques of vector and matrix calculation and array broadcasting are also achieved with spreadsheet techniques, and logical queries and for-loops operate on spreadsheets from simple Visual Basic macros. So, starting to learn scientific calculation with Excel, e.g., at High School, is a targeted road to scientific computing. The primary target groups of this book are students with a major or minor subject in physics, who have interest in computational techniques and at the same time want to deepen their knowledge of physics. Math, physics and computer science teachers and Teacher Education students will also find a companion in this book to help them integrate computer techniques into their lessons. Even professional physicists who want to venture into Scientific Computing may appreciate this book.

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The relationship between morality and religion has long been controversial, familiar in its formulation as Euthyphro’s dilemma: Is an act right because God commanded it or did God command it because it is right. In Morality and Religion: The Jewish Story, renowned scholar Avi Sagi marshals the breadth of philosophical and hermeneutical tools to examine this relationship in Judaism from two perspectives. The first considers whether Judaism adopted a thesis widespread in other monotheistic religions known as 'divine command morality,' making morality contingent on God’s command. The second deals with the ways Jewish tradition grapples with conflicts between religious and moral obligations. After examining a broad spectrum of Jewish sources—including Talmudic literature, Halakhah, Aggadah, Jewish philosophy, and liturgy—Sagi concludes that mainstream Jewish tradition consistently refrains from attempts to endorse divine command morality or resolve conflicts by invoking a divine command. Rather, the central strand in Judaism perceives God and humans as inhabiting the same moral community and bound by the same moral obligations. When conflicts emerge between moral and religious instructions, Jewish tradition interprets religious norms so that they ultimately pass the moral test. This mainstream voice is anchored in the meaning of Jewish law, which is founded on human autonomy and rationality, and in the relationship with God that is assumed in this tradition.

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This book describes the utilization of different soft computing techniques and their optimization for providing an accurate and efficient medical diagnosis. The proposed method provides a precise and timely diagnosis of the risk that a person has to develop a particular disease, but it can be adaptable to provide the diagnosis of different diseases. This book reflects the experimentation that was carried out, based on the different optimizations using bio-inspired algorithms (such as bird swarm algorithm, flower pollination algorithms, and others). In particular, the optimizations were carried out to design the fuzzy classifiers of the nocturnal blood pressure profile and heart rate level. In addition, to obtain the architecture that provides the best result, the neurons and the number of neurons per layers of the artificial neural networks used in the model are optimized. Furthermore, different tests were carried out with the complete optimized model. Another work that is presented in this book is the dynamic parameter adaptation of the bird swarm algorithm using fuzzy inference systems, with the aim of improving its performance. For this, different experiments are carried out, where mathematical functions and a monolithic neural network are optimized to compare the results obtained with the original algorithm. The book will be of interest for graduate students of engineering and medicine, as well as researchers and professors aiming at proposing and developing new intelligent models for medical diagnosis. In addition, it also will be of interest for people working on metaheuristic algorithms and their applications on medicine.

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This book presents key principles of the hydraulics of river basins, with a unique focus on the interplay between stream flows and sediment transport. Addressing a number of basic topics related to the hydraulics of river systems, above all it emphasizes applicative aspects in order to provide the reader with a solid grasp of river engineering. The understanding of the river hydraulics is essential for the assessment of optimum locations for the conservation of water resources and its structures. This book will be interesting to readers and researchers working in the specialized area of river hydraulics of Ganga basin, Narmada, Tapi, Godavari, and other basins of India. It consists of review on hydraulics of meandering river; hydraulic design of reservoir in permeable pavement; optimization of hydraulic design; hydraulic investigations to optimize the design of spillway and design of energy dissipater; and analysis of performance of orifice spillway using computational fluid dynaics

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This book provides a comprehensive assessment and presentation of various feasible application of electric propulsion system, considering their weight, volume, reliability, and fault tolerance. The results of feasibility analysis can be used today or in the near future for development of electric propulsion system for the ships, planes, helicopters, and spacecrafts. To solve the above task, new theoretical approaches are applied, including combined random process methods, the Lz-transform technique for multistate systems, and statistical data processing.

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This book provides how-to recommendations and detailed guides for using transradial access in interventional radiology. A relatively new and growing technique, transradial access is most commonly found within interventional cardiology. This book approaches those cardiac uses of transradial access while extending its use to other body sites and disease states. The book details the interventional radiologist’s transition to using transradial access across a broad spectrum of clinical applications, allowing them to better introduce it into their practice and to their patients. The text is divided into three sections: overview, clinical applications, and novel applications and techniques. The first section covers the history of transradial access, the initial patient assessment, and how to prepare for a procedure. The second section is divided into different diseases and interventional situations where transradial access could be considered, including subclavian artery stenosis and endovascular neurosurgery. The third section includes coverage of how to perform the latest techniques and projections for future procedures. This guide provides a manual of operations to assist in the setup of the practice, from office visit to procedure room to recovery across a variety of service lines and patient populations. Key take home points and equipment summaries accompany each chapter, allowing the user to easily navigate the book to accelerate his or her practice. This is an ideal guide for interventional radiologists.

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This book comprehensively reviews soft tissue, bone, ligament, and nerve injury of the hand and wrist unique to baseball. Organized into three sections, the book begins with a discussion on fractures of the hand and wrist, including the distal radius, scaphoid, and phalanges. Following this, section two examines ligament injuries from the wrist to the thumb. Section three then concludes the book with an analysis of tendon and nerve injuries. Chapters include high-quality images and tables to supplement expertly written text.Unique and thorough, Hand and Wrist Injuries in Baseball is an invaluable resource for orthopedics surgeons and sports medicine specialists, as well as primary care physicians, emergency room physicians, pediatricians, athletic trainers, and therapists.

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This textbook helps students truly understand how to apply the principles behind corporate finance in a real world context from both a firm and investor perspective. In its second edition, this text focuses on traditional theory applied to a holistic and realistic business case study, written as a novel set in current times so that all readers can relate. As such, this textbook offers readers both a quantitative and qualitative perspective on topics such as capital budgeting, time value of money, corporate risk, and capital structure. The sections are laid out to mirror the financial decision process, making it easier for readers to grasp the idea of the corporate financial life cycle. New topics such as socially responsible investing and private capital markets are also incorporated into this edition. Finally, PowerPoint slides, answer keys and data sets are available online for instructors.

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The book systematically describes the clinical and scientific aspects of cardiovascular calcification. Chapters detail the mechanisms associated with arterial and valve calcification, relevant risk factors, pathophysiology and the latest therapeutic techniques. Recent diagnostic technological developments including how computed tomography (CT) scanning can be utilized along with Agatston score to quantify coronary arterial calcification when investigating whether a patient for sub-clinical atherosclerosis are covered. The correlation with the presence of arterial calcification and extent of coronary stenosis is also explored. Cardiovasular Calcification details relevant aspects of the basic science and reviews the latest pathological and therapeutic techniques used in treating patients with cardiovascular calcification. It is therefore an essential resource for practicing cardiologists, cardiac surgeons, vascular specialists and radiologists.

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This open access edited volume is a comparative effort to discern the short-term educational impact of the covid-19 pandemic on students, teachers and systems in Brazil, Chile, Finland, Japan, Mexico, Norway, Portugal, Russia, Singapore, Spain, South Africa, the United Kingdom and the United States. One of the first academic comparative studies of the educational impact of the pandemic, the book explains how the interruption of in person instruction and the variable efficacy of alternative forms of education caused learning loss and disengagement with learning, especially for disadvantaged students. Other direct and indirect impacts of the pandemic diminished the ability of families to support children and youth in their education. For students, as well as for teachers and school staff, these included the economic shocks experienced by families, in some cases leading to food insecurity and in many more causing stress and anxiety and impacting mental health. Opportunity to learn was also diminished by the shocks and trauma experienced by those with a close relative infected by the virus, and by the constrains on learning resulting from students having to learn at home, where the demands of schoolwork had to be negotiated with other family necessities, often sharing limited space. Furthermore, the prolonged stress caused by the uncertainty over the resolution of the pandemic and resulting from the knowledge that anyone could be infected and potentially lose their lives, created a traumatic context for many that undermined the necessary focus and dedication to schoolwork. These individual effects were reinforced by community effects, particularly for students and teachers living in communities where the multifaceted negative impacts resulting from the pandemic were pervasive. This is an open access book.

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In the present era dominated by computers, graph theory has come into its own as an area of mathematics, prominent for both its theory and its applications. One of the richest and most studied types of graph structures is that of the line graph, where the focus is more on the edges of a graph than on the vertices. A subject worthy of exploration in itself, line graphs are closely connected to other areas of mathematics and computer science. This book is unique in its extensive coverage of many areas of graph theory applicable to line graphs. The book has three parts. Part I covers line graphs and their properties, while Part II looks at features that apply specifically to directed graphs, and Part III presents generalizations and variations of both line graphs and line digraphs.Line Graphs and Line Digraphs is the first comprehensive monograph on the topic. With minimal prerequisites, the book is accessible to most mathematicians and computer scientists who have had an introduction graph theory, and will be a valuable reference for researchers working in graph theory and related fields.

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This guide walks you through the set-up, supplies, nursing considerations, troubleshooting, and steps to successfully assist during cutting edge interventional Gastroenterological procedures that are being performed to offer patients a safer and more cost effective treatment option. This key resource contributes, as the first of its kind, by helping endoscopic surgical centers to prepare for and train staff in order to offer these new and on the rise procedures to their patients. It goes into detail on each procedure and why a patient would benefit from it. Pictures will be included to demonstrate what the procedure will look like. A detailed step-by-step manual including photos will be put together on each case describing the set-up, pre, intra, and post-procedure care and responsibilities.This step-by-step guide includes a full range of highly advanced procedures that are on the forefront of medicine. It will help Endoscopy nurses and technicians, as well as radiology technicians and endoscopists, who are being trained to perform or assist in these new and complex procedures.

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As the application of smart technologies for monitoring environmental activities becomes more widespread, there is a growing demand for solutions that can help analyze the risk factors and impacts on the environment by focusing on energy consumption, storage, and management. This book is designed to serve as a knowledge-sharing platform, focusing on the emerging models, architectures, and algorithms being developed for smart computational technologies that can lead to efficient energy conservation and environmental sustainability.

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Par-4 is a naturally occurring tumor suppressor. Studies have indicated that overexpression of Par-4 selectively induces apoptosis in cancer cells while leaving normal, health, cells unaffected. Mechanisms contributing to this cancer-selective action of Par-4 have been associated with PKA activation of intracellular Par-4 in cancer cells or GRP78 expression primarily on the surface of cancer cells. On the other hand, endogenous Par-4 sensitizes cells to the action of a broad range of apoptotic inducers acting via the extrinsic and intrinsic pathways. A number of binding partners of Par-4 have been identified and shown to regulate Par-4 function in cancer and other diseases, such as Alzheimer’s and major depression. Recent studies have recognized a number of natural products, dietary supplements, synthetic molecules and FDA-approved drugs that induce the secretion of Par-4 protein to cause apoptosis in primary or metastatic tumors, one of which is in clinical trials. More than 50 different laboratories worldwide are involved in Par-4 based research of this unique protein that has progressed from the bench to clinical trials. This second, companion volume will provide a comprehensive overview of Par-4’s role in cancer and other diseases. Chapters are written by leading researchers, and will be useful for a broad audience across the scientific community, particularly students and trainees, who are the next generation of scientists and clinicians to participate in new studies and discoveries on Par-4.

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This book presents a collection of recent research works related to blast resistant design, building pathologies, seismic coating, bottle-shaped concrete struts, delayed ettringite formation and waterproofing. It features eight chapters on building pathologies as well as a detailed set of references and suggestions for further reading. Offering a systematic review of the current state of knowledge, it is a valuable resource for scientists, students, practitioners, and lecturers in various scientific and engineering disciplines, including civil and materials engineering, as well as and other interested parties.

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This book comprises high-quality refereed research papers presented at The Second International Symposium on Computer Science, Digital Economy and Intelligent Systems (CSDEIS2020), held in Moscow, Russia, on December 18–20, 2020, organized jointly by Moscow State Technical University and the International Research Association of Modern Education and Computer Science. The topics discussed in the book include state-of-the-art papers in computer science and their technological applications; intelligent systems and intellectual approaches; digital economics and methodological approaches. It is an excellent source of references for researchers, graduate students, engineers, management practitioners, and undergraduate students interested in computer science and their applications in engineering and management.

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Crises and disruptions can lead to important changes in economic, social and institutional environments. This collection of influential JIBS articles and original commentaries highlights that MNEs are affected by, and respond to, crises and disruptions differently than domestic firms due to their geographically dispersed operations and wider range of experiences from being active in diverse environments. MNEs can exhibit greater flexibility to ‘avoid’ locations characterised by crises and disruptions, and when affected, they can deploy a more refined set of responses relative to domestic firms.Each article is accompanied by a brand new editorial piece, bringing the research right up to date and reflecting on the impact of the article today. In this way, the book offers an integrated perspective on the antecedents, outcomes and potential opportunities associated with a variety of crises and disruptions such as disease outbreaks, natural disasters, climate change and political unrest.An ideal resource for students and researchers, this book offers new perspectives, policy and practical recommendations as well as a discussion of future trends. The volume concludes with a novel analysis on how businesses can move forward in a post-Covid world.

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Over the past decade the world has seen the rise of the fascinating and diverse field currently recognized as nanotechnology. This book covers a broad spectrum of topics within nanotechnology, including synthesis techniques, various innovative characterization techniques, growth mechanisms of nanomaterials, the physics and chemistry of nanomaterials, diverse functionalization methods, and the various applications of nanomaterials in biology, therapeutics, energy, food science, and environmental science. It also discusses applications of nanostructured materials, integrative applications such as nano- and micro-electronic sensor devices, as well as agricultural and environmental remediation applications. The book also includes a discussion of advances in functionalized nanomaterials (0D, 1D, 2D and 3D) and covers the early stages of the development of functionalized nanostructures, considering the future for 2D nanomaterials and 3D objects. Additionally, it includes a chapter on nanomaterial research development that highlights work on the life-cycle analysis of nanostructured materials and toxicity aspects.This book proves useful for researchers and professionals working in the field of nanomaterials and green technology, as well as in the field of nanotechnology. It should be useful to students and specialized researchers in a number of disciplines ranging from biology, chemistry, and materials science to engineering and manufacturing in both academia and industry.

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This book covers the optical and electrical properties of nanoscale materials with an emphasis on how new and unique material properties result from the special nature of their electronic band structure. Beginning with a review of the optical and solid state physics needed for understanding optical and electrical properties, the book then introduces the electronic band structure of solids and discusses the effect of spin orbit coupling on the valence band, which is critical for understanding the optical properties of most nanoscale materials. Excitonic effects and excitons are also presented along with their effect on optical absorption.2D materials, such as graphene and transition metal dichalcogenides, are host to unique electrical properties resulting from the electronic band structure. This book devotes significant attention to the optical and electrical properties of 2D and topological materials with an emphasis on optical measurements, electrical characterization of carrier transport, and a discussion of the electronic band structures using a tight binding approach. This book succinctly compiles useful fundamental and practical information from one of the fastest growing research topics in materials science and is thus an essential compendium for both students and researchers in this rapidly moving field.

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This Fourth Edition updates the "Solutions Manual for Econometrics" to match the Sixth Edition of the Econometrics textbook. It adds problems and solutions using latest software versions of Stata and EViews. Special features include empirical examples replicated using EViews, Stata as well as SAS. The book offers rigorous proofs and treatment of difficult econometrics concepts in a simple and clear way, and provides the reader with both applied and theoretical econometrics problems along with their solutions. These should prove useful to students and instructors using this book.

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This book addresses the importance of human factors in optimizing the learning and training process. It reports on the latest research and best practices relating to the application of behavioral and cognitive science, and new technologies in the design of instructional and training content. It proposes innovative strategies for improving the learning and training experience and outcomes in different contexts, including lower and higher education, and different industry sectors. A special emphasis is given to digital and distance learning, gamification, and virtual training. Gathering contributions to the AHFE 2021 Conference on Human Factors in Training, Education, and Learning Sciences, held virtually on July 25-29, 2021, from USA, this book offers extensive information and a thought-provoking guide for both researchers and practitioners in the field of education and training.

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This Springer Handbook comprehensively covers the topic of semiconductor devices, embracing all aspects from theoretical background to fabrication, modeling, and applications.Nearly 100 leading scientists from industry and academia were selected to write the handbook's chapters, which were conceived for professionals and practitioners, material scientists, physicists and electrical engineers working at universities, industrial R&D, and manufacturers.Starting from the description of the relevant technological aspects and fabrication steps, the handbook proceeds with a section fully devoted to the main conventional semiconductor devices like, e.g., bipolar transistors and MOS capacitors and transistors, used in the production of the standard integrated circuits, and the corresponding physical models. In the subsequent chapters, the scaling issues of the semiconductor-device technology are addressed, followed by the description of novel concept-based semiconductor devices. The last section illustrates the numerical simulation methods ranging from the fabrication processes to the device performances.Each chapter is self-contained, and refers to related topics treated in other chapters when necessary, so that the reader interested in a specific subject can easily identify a personal reading path through the vast contents of the handbook.

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This book is Volume I of a two-volume set on antitrust policy, analyzing the economic efficiency and moral desirability of various tests for antitrust legality, including those promulgated by US and EU antitrust law. The overall study consists of three parts. Part I (Chapters 1-8) introduces readers to the economic, moral, and legal concepts that play important roles in antitrust-policy analysis. Part II (Chapters 9-16) analyzes the impacts of eight types of conduct covered by antitrust policy and various possible government responses to such conduct in terms of economic efficiency, the securing of liberal moral rights, and the instantiation of various utilitarian, non-utilitarian-egalitarian, and mixed conceptions of the moral good. Part III (Chapters 17-18) provides detailed information on US antitrust law and EU competition law, and compares the extent to which—when correctly interpreted and applied—these two bodies of law could ensure economic efficiency, protect liberal moral rights, and instantiate various morally defensible conceptions of the moral good. This first volume contains Part I and the first two chapters of Part II of the overall study—the two chapters that focus on oligopolistic and predatory conduct of all kinds, respectively. The book will appeal to undergraduate and graduate students of economics and law who are interested in welfare economics, antitrust legality and the General Theory of the Second Best.

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This book offers timely insights into research on numerical and experimental fluid mechanics and aerodynamics, mainly for (but not limited to) aerospace applications. It reports on findings by members of the STAB (German Aerospace Aerodynamics Association) and DGLR (German Society for Aeronautics and Astronautics) and covers both nationally and EC-funded projects. Continuing on the tradition of the previous volumes, the book highlights innovative solutions, promoting translation from fundamental research to industrial applications. It addresses academics and professionals in the field of aeronautics, astronautics, ground transportation, and energy alike.

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The recent proliferation of populist movements worldwide — along with the often dangerous, demagogic leaders that accompany them — have prompted questions about the underlying conditions that give rise to such troubling developments. Leadership Unhinged: Essays on the Ugly, the Bad and the Weird examines what is going on at a deeper level, both collectively and individually, between leaders and followers. Employing theories derived from psychoanalytic psychology, developmental psychology, neuroscience and evolutionary psychology, these essays help to unravel and expose the pathological leader-follower dynamics that generate such movements. The book is infused with Kets de Vries’s now famous and inimitable style of analysis, which draws from myths, creates fairy tales, and uses irony and metaphor to bring his conclusions into greater relief and trigger new insights. As Kets de Vries explains, effective leaders have the capacity to bring people together and even make them better, stronger. Doing so suggests that those leaders are value driven, able to set a moral tone. Yet, when such a tone is absent or, at worst, twisted toward the destructive, leadership quickly becomes dangerous. History has shown the devastation left in the wake of unhinged leaders who have gone unchecked. To become fully conscious of the conditions that allow for the emergence of such leaders has become a moral requirement of our time. In ways both moving and entertaining, Kets de Vries’s new contribution puts us in a better position to fulfil that requirement.

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The field of immuno-oncology continues to rapidly evolve as new insights to fight and treat cancer emerge. The fourth edition of Immunotherapy provides the most current overview of immuno-oncology in different cancer types and toxicities associated with immunotherapy. While immunotherapy has revolutionized the treatment landscape of several solid malignancies, several challenges still exist.Only a subset of patients derive clinical benefits; some do not respond at all, and others respond initially, only for their disease to progress later. Because these drugs can activate a broad range of immune cells, patients suffer from a unique set of side effects known as immune-related adverse events. As more immunotherapeutic agents are used in the clinic, it is important to provide updates about current and ongoing developments in the field to further research efforts and inform treatment decisions.The fourth edition will have a new focus on strategies to overcome the challenges associated with immunotherapy. Chapters will discuss topics such as biomarkers of response, resistance mechanisms, role of imaging in predicting immune-related adverse events, and management of immune-related adverse events. Written by leading experts conducting cutting-edge research, readers will gain up-to-date knowledge on the current state and future of immunotherapy.

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This open access book offers an updated examination of the institutionalisation of political science in sixteen latecomer or peripheral countries in Europe. Its main theme is how political science as a science of democracy is influenced and how it responds to the challenges of the new millennium. The chapters, built upon a common theoretical framework of institutionalisation, are evidence-based and comparative. Overall, the book diagnoses diversity among the country cases due to their take-off points and varied political and economic trajectories.

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