Search results for ""author franz""

The neurosciences have been an especially difficult field for drug discovery. Because of the huge complexity of the nervous system and poor understanding of most psychiatric and neurological diseases, most drugs currently available are the result of chance observations rather than a truly comprehensive approach. However, this situation has begun to change. Enormous progress in molecular biology has yielded breakthrough discoveries of the causes of nervous system diseases, opening the door for better-targeted and entirely novel therapies. Reflecting these recent advances, Drug Discovery for Nervous System Diseases presents the latest techniques and approaches for drug discovery, organizing them according to diseases rather than classes of drugs or drug targets, as past books have done. Written with optimistic anticipation of great progress still to come, this text provides both a guide to present realities and a look to future possibilities in this burgeoning field. Coverage in Drug Discovery for Nervous System Diseases includes: * Fundamentals of drug discovery-receptors, target selection, and drug development * Schizophrenia * Depression * Anxiety disorders * Alzheimer's disease * Parkinson's disease * Ischemic stroke, brain, and spinal cord injury * Other neurodegenerative diseases * Sleep disorders * Epilepsy * Pain This practical handbook features a uniform presentation for each chapter, with a brief description of existing drugs leading to recent molecular biological and genetic findings, translational research and the interface to clinical trials, and finally an outlook on future drug targets. Rich illustrations-schematic diagrams and tables-provide a dynamic visual experience throughout the text. A unique and up-to-date guide to a field currently undergoing a major growth spurt, Drug Discovery for Nervous System Diseases offers both practitioners and advanced students an unparalleled resource.

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This compendium contains and explains essential mathematical formulas for financial economics and finance. A broad range of aids and supportive examples will help readers to understand the formulas and their practical applications. This mathematical formulary is presented in a practice-oriented, clear, and understandable manner, as it is needed for meaningful and relevant application in global business, as well as in the academic setting and economic practice. The topics presented include but are not limited to accumulation, discounting, annuity, interest calculation, redemption, investment, effective interest rates, ICMA, depreciation, and present value.Given its scope, the book offers an indispensable reference guide and is a must-read for undergraduate and graduate students, as well as managers, scholars, and lecturers in financial economics and business.

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This 2nd edition compendium contains and explains essential statistical formulas within an economic context. Expanded by more than 100 pages compared to the 1st edition, the compendium has been supplemented with numerous additional practical examples, which will help readers to better understand the formulas and their practical applications. This statistical formulary is presented in a practice-oriented, clear, and understandable manner, as it is needed for meaningful and relevant application in global business, as well as in the academic setting and economic practice.The topics presented include, but are not limited to: statistical signs and symbols, descriptive statistics, empirical distributions, ratios and index figures, correlation analysis, regression analysis, inferential statistics, probability calculation, probability distributions, theoretical distributions, statistical estimation methods, confidence intervals, statistical testing methods, the Peren-Clement index, and the usual statistical tables.Given its scope, the book offers an indispensable reference guide and is a must-read for undergraduate and graduate students, as well as managers, scholars, and lecturers in business, politics, and economics.

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In addition to the title piece, originally arranged for no less than 59 different combinations of instruments - this collection contains "Vienna Jubilee Overture" as well "Morning, Noon and Night in Vienna"; "Beautiful Galatea"; and "Light Cavalry".

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