Search results for ""Taylor Francis""

How does the therapeutic frame help therapists in their practice? The Therapeutic Frame in the Clinical Context examines some of the key issues inherent in the intimate and very often intense therapeutic relationship. It addresses and clarifies perspectives on the creation of a therapeutic environment that is conducive to therapy. The book addresses specific aspects of the therapeutic frame. How does a client feel about unexpectedly meeting her psychotherapist's son or daughter? How does a psychotherapist or counsellor practice within a 'frameless', often intrusive environment, in acute hospital wards? How does a counsellor manage the frame in the face of a life-threatening illness? Using a wealth of examples from clinical practice, The Therapeutic Frame in the Clinical Context examines these issues and more, in a range of settings including the NHS, private practice, and the workplace, and provides valuable guidelines from a range of theoretical perspectives, including Jungian and psychoanalytic.

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Why are some people more vulnerable to common mental disorders than others?What effects do genes and environments exert on the development of mental disorders?The Origins and Course of Common Mental Disorders describes the nature, characteristics and causes of common emotional and behavioural disorders as they develop across the lifespan, providing a clear and concise account of recent advances in our knowledge of the origins and history of anxious, depressive, anti-social, and substance related disorders.Combining a lifespan approach with developments in neurobiology, this book describes the epidemiology of emotional and behavioural disorders in childhood, adolescence and adult life. David Goldberg and Ian Goodyer demonstrate how both genes and environments exert different but key effects on the development of these disorders and suggest a developmental model as the most appropriate for determining vulnerabilities for psychopathology. Divided into four sections, the book covers:the nature and distribution of common mental disorders the biological basis of common disorders the human life cycle relevant to common disorders the developmental model. This highly readable account of the origins of emotional and behavioural disorders will be of interest to behavioural science students and all mental health professionals including psychiatrists, psychologists, social workers, nurses, and counsellors.

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Personal relationships concern us all, they are essential to our becoming who we are and constitute our most vital experience of what it is like to be alive and human. This book proposes a new approach to understanding who we are based on the work of Ronald Fairbairn, John Macmurray and Ian Suttie, whose ideas provide a positive perspective on our future collective possibilities.Personal Relations Theory presents a new and comprehensive account of Fairbairn's mature theory. Part I provides a thorough overview of Fairbairn's work and its ramifications for our understanding of creativity and the nature of inner reality. Part II covers Fairbairn's relationship to Macmurray and Suttie, and their relevance to realist philosophy, the scientific status of psychoanalysis, attachment theory and the politics of the personal relations view point. Subjects discussed in depth include: Internal objects and inner reality: Fairbairn and Klein Fairbairn's theory of art in the light of his mature model of mind The preconscious and psychic change in Fairbairn's model of mind The politics of attachment theory and personal relations theory: Fairbairn, Suttie and Bowlby The combination of Fairbairn, Macmurray and Suttie presented here forms an original strand of object relations theory, which has implications and consequences for a wide spectrum of concerns. This book will be of value to anyone interested in psychoanalysis, especially in relation to politics, society and the arts.

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Posttraumatic Stress Disorder remains one of the most contentious and poorly understood psychiatric disorders. Evolution and Posttraumatic Stress provides a valuable new perspective on its nature and causes.This book is the first to examine PTSD from an evolutionary perspective. Beginning with a review of conventional theories, Chris Cantor provides a clear and succinct overview of the history, clinical features and epidemiology of PTSD before going on to introduce and integrate evolutionary theory. Subjects discussed include:The evolution of human defensive behaviours A clinical perspective of PTSD Defence in overdrive: evolution, PTSD and parsimony This original presentation of PTSD as a defensive strategy describes how the use of evolutionary theory provides a more coherent and successful model for diagnosis, greatly improving understanding of usually mystifying symptoms. It will be of great interest to psychiatrists, psychotherapists, psychologists, and anthropologists.

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Illustrated with richly detailed clinical vignettes, Seeds of Illness, Seeds of Recovery offers a fascinating investigation into the origins, modes and treatment of psychical suffering. Antonino Ferro provides a clear account of his conception of the way the mind works, his interpretation of the analytic understanding of psychopathology, his reconceptualization of the therapeutic process, and implications for analytic technique derived from his view of the therapeutic action of psychoanalysis. Drawing on and developing the ideas of Wilfred Bion, Ferro gives a unique perspective on subjects including: Container Inadequacy and Violent Emotions The waking dream and narrations 'Evidence': starting again from Bion Self-analysis and gradients of functioning in the analyst. This highly original approach to the problem of therapeutic factors in psychoanalysis will be of interest to all practising and training psychoanalysts and psychotherapists.

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Co-existing mental health and drug and alcohol problems occur frequently in primary care and clinical settings. Despite this, health professionals rarely receive training in how to detect, assess and formulate interventions for co-existing problems and few clinical guidelines exist.This Handbook provides an exciting and highly useful addition to this area. Leading clinicians from the UK, the US and Australia provide practical descriptions of assessments and interventions for co-existing problems. These will enable professionals working with co-existing problems to understand best practice and ensure that people with co-existing problems receive optimal treatment. A range of overarching approaches are covered, including:• working within a cognitive behavioural framework;• provision of consultation-liaison services, training and supervision;• individual, group and family interventions; and• working with rurally isolated populations.The contributors also provide detailed descriptions of assessments and treatments for a range of disorders when accompanied by drug and alcohol problems, including anxiety, depression, schizophrenia, bipolar disorder and learning difficulties. The Clinical Handbook of Co-existing Mental Health and Drug and Alcohol Problems will enhance clinicians’ confidence in working with people with co-existing problems. It will prove a valuable resource for all psychologists, psychiatrists, counsellors, social workers and all those working in both primary and secondary care health settings.

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In Glacial Times, Salomon Resnik brings together various facets of his work as a psychoanalyst and psychiatrist, working in both the private sector and in institutional settings and in a wide range of cultural contexts, to provide a careful summary of a lifetime of clinical work. Drawing on a wide range of psychoanalytic, philosophical and literary sources, and vignettes from the author's extensive clinical experience, this book brings the subject of psychosis to life and demonstrates how the study of psychoanalysis and psychosis forces us to confront fundamental ontological questions. Subjects covered include: Transmission and Learning The role of the body in psychosis The Universe of Madness: Frozen words and thoughts The Internal world and the philosophy of the unconcsious Psychotic thinking and language The Symbolic order and its deficiencies. This synthesis of over fifty years of experience as a psychoanalyst and psychiatrist treating psychotic patients will fascinate anyone working in these fields.

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Recent years have seen a growth in the numbers of studies of substance abuse and dependence in adolescence, focusing on prevalence, risk factors, comorbidity, course and outcome. At the same time, numerous prevention and intervention strategies have been developed. Substance Abuse and Dependence in Adolescence presents a comprehensive review of state-of-the-art empirical and practical information on this topic.Cecilia A. Essau, along with an eminent group of international researchers and clinicians, summarises the most recent empirical findings and state-of-the-art knowledge on substance abuse and dependence in adolescence and includes comprehensive information on prevention and treatment. Substance Abuse and Dependence in Adolescence contains:* general issues related to substance use disorders* epidemiology, comorbidity, course, outcome and risk factors* the prevention and intervention of substance abuse and dependence* a discussion of progress and unresolved issues in substance use disorders* recommendations for future studies in the field.Substance Abuse and Dependence in Adolescence will be an invaluable resource for students, researchers, and other professionals working in the fields of psychology, psychiatry, paediatrics, social work and other mental health professions.

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Many people come for help because they remain stuck in a destructive relationship, job, legal battle or memories of child abuse. A growing number of therapists believe that forgiveness is of crucial importance in helping people break away from these patterns of resentment and revenge. Does forgiveness help? Or is the concept out of date in our more secular society? Forgiveness and the Healing Process considers this debate. Experienced contributors: * Consider the place of forgiveness in working with individuals and couples* Explore the benefits of mediation as a way forward both for the individual and the organisation, and also within the criminal justice system* Offer a valuable insight into South Africa's Truth and Reconciliation Commission and the crucial role of forgiveness in post-apartheid South Africa* Examine a client's view of seeking forgiveness* Present new frameworks for workers seeking to help people cope with trauma and injustice.Forgiveness and the Healing Process helps counsellors, psychotherapists, social workers, mediators, psychiatrists, and those working in the criminal justice system understand how forgiveness can facilitate the therapeutic process.Cynthia Ransley is a lecturer and course leader in social work at Brunel University. She is an integrative psychotherapist, supervisor and trainer in London.Terri Spy is a counselling psychologist and fellow of the British Association for Counselling and Psychotherapy. She is a London-based integrative psychotherapist, supervisor and trainer.Contributors: Michael Carroll, Jane Cooper, Gill Eagle, Maria Gilbert, Joy Green, Guy Masters, Fathima Moosa, Cynthia Ransley, Terri Spy, Gill Straker.

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This book will interest clinicians who have wondered what professional practice would be like in the corporate setting and want to learn more about the psychological and organizational dynamics that 'drive' executive behavior. Based on the premise that leadership effectiveness is a function of both leader productivity and health, this book reviews the latest information and research data and offers case studies to illustrate specific strategies for maximizing executive health. Len Sperry has been consulting to executives and organizations for 30 years and has written numerous articles and several books on executives and workplace dynamics.

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The Encyclopedia of Italian Literary Studies is a two-volume reference book containing some 600 entries on all aspects of Italian literary culture. It includes analytical essays on authors and works, from the most important figures of Italian literature to little known authors and works that are influential to the field. The Encyclopedia is distinguished by substantial articles on critics, themes, genres, schools, historical surveys, and other topics related to the overall subject of Italian literary studies. The Encyclopedia also includes writers and subjects of contemporary interest, such as those relating to journalism, film, media, children's literature, food and vernacular literatures. Entries consist of an essay on the topic and a bibliographic portion listing works for further reading, and, in the case of entries on individuals, a brief biographical paragraph and list of works by the person. It will be useful to people without specialized knowledge of Italian literature as well as to scholars.

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This three-volume work offers a comprehensive review of the pivotal concepts, measures, theories, and practices that comprise criminology and criminal justice.No longer just a subtopic of sociology, criminology has become an independent academic field of study that incorporates scholarship from numerous disciplines including psychology, political science, behavioral science, law, economics, public health, family studies, social work, and many others. The three-volume Encyclopedia of Criminology presents the latest research as well as the traditional topics which reflect the field's multidisciplinary nature in a single, authoritative reference work. More than 525 alphabetically arranged entries by the leading authorities in the discipline comprise this definitive, international resource. The pivotal concepts, measures, theories, and practices of the field are addressed with an emphasis on comparative criminology and criminal justice. While the primary focus of the work is on American criminology and contemporary criminal justice in the United States, extensive global coverage of other nations' justice systems is included, and the increasing international nature of crime is explored thoroughly.Providing the most up-to-date scholarship in addition to the traditional theories on criminology, the Encyclopedia of Criminology is the essential one-stop reference for students and scholars alike to explore the broad expanse of this multidisciplinary field.

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This comprehensive, alphabetical encyclopedia of more than 300 easy-to-read entries is the first resource for anyone who wants reliable information or background material on the significant decisions of the Supreme Court, the history of the Court, the justices (every justice is profiled), the powers of the Court, and how the institution has evolved from its origins to the present. Outstanding Academic Book

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Each volume of the Dictionary of World Biography contains 250 entries on the lives of the individuals who shaped their times and left their mark on world history. This is not a who's who. Instead, each entry provides an in-depth essay on the life and career of the individual concerned. Essays commence with a quick reference section that provides basic facts on the individual's life and achievements. The extended biography places the life and works of the individual within an historical context, and the summary at the end of each essay provides a synopsis of the individual's place in history. All entries conclude with a fully annotated bibliography.

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This concluding volume in the series presents the work of faculty who have been moved to make sustainability the focus of their work, and to use service learning as one method of teaching sustainability to their students. The chapters in the opening section of this book – Environmental Awareness – offer models for opening students to the awareness of the ecological aspects of sustainability, and of the interdependence of the ecosystem with human and with institutional decisions and behavior; and illustrate how they, in turn, can share that awareness with the community.The second section – Increasing Civic Engagement – explores means for fostering commitment to community service and experiencing the capacity to effect change.The concluding section – Sustainability Concepts in Business and Economics – addresses sustainability within the business context, with emphasis on the “triple bottom line”—the achievement of profitability through responsible environmental practice and respect for all stakeholders in the enterprise.

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This volume explores multiple examples of how to connect classrooms to communities through service learning and participatory research to teach issues of social justice. The various chapters provide examples of how collaborations between students, faculty, and community partners are creating models of democratic spaces (on campus and off campus) where the students are teachers and the teachers are students. The purpose of this volume is to provide examples of how service learning can be integrated into courses addressing social justice issues. At the same time, it is about demonstrating the power of service learning in advancing a course content that is community-based and socially engaged.To stimulate the adaptation of the approaches described in these books, each volume includes an Activity / Methodology table that summarizes key elements of each example, such as class size, pedagogy, and other disciplinary applications. Click here for the table to this title.

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Ulead DVD Workshop is DVD-authoring software designed for video professionals and enthusiasts working on the Windows platform. It permits users to import video from digital or analog sources with sophisticated MPEG capture and conversion tools and build professional looking still or motion menus using an extensive set of design tools. Instant DVD Workshop 2.0 presents carefully detailed screen shots and step-by-step directions illustrating how to use DVD Workshop software. Beginning with the proper installation of the application, it covers the full scope of functions, including managing media, importing stills and graphics, editing video, inserting audio files, creating menus, and finish authoring, with professional tips and techniques covering workflow and other topics provided along the way.

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This unique synthesis of chapters from top experts in their fields, targets the very important and upcoming area of cancer biomarkers and the need for better and more rigorous design and clinical trial. The book covers several aspects of cancer molecular markers from innovation, screening, controversies and future directions. The primary target audience for the book includes PhD and MD students, researchers, biologists, medical doctors and professionals who are interested in mechanistic studies on cancer diagnosis and translational benefits from personalized cancer treatment using the new era of biomarkers.

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The healthcare professional is now more educated, very often to the degree and masters level. Concomitantly, the demand for comprehensive and focused evidenced-based text and scientific literature covering single areas of nursing and healthcare science or treatment has also increased. This volume on Asthma covers, inter alia, asthma care in primary care centers, rhinosinusitis and asthma, asthma and psychological distress, inhalation techniques for different inhalers, emergency treatment for acute asthma, therapy for elderly patients, treatment for pediatric asthma, nursing care at home and more.

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Healthcare has been transformed from a “this is what you do” concept to a profession that has a significant educational and scientific basis with an ethos of evidence-based material. The demand for comprehensive and focused evidenced-based text and scientific literature covering single areas of nursing and healthcare science or treatment has also increased. This then is the rational for the present series. The volume on Arthritis covers, rheumatoid arthritis, cytokines, leukocyte immunoglobulin-like receptors, alleles, cardiovascular risk, disease outcomes, treatment protocols, and drugs for arthritis.

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It is perhaps because fishes live in a buoyant medium, whether it be fresh or sea water, that they show a diversity in body shapes that is unparalleled by other vertebrates. There is also a unique diversity in the modes of reproduction, whether by external or internal fertilization, and this, with the morphology and fine structure of the reproductive system and its components, is the subject of the present volume. A large part of this book deals with the ultrastructure of spermatozoa, with some discussion of phylogenetic implications.

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Tomatoes have become a dietary staple for humans in many parts of the world. The characteristic deep red color of the ripe tomato fruit and related products is mainly due to lycopene. Lycopene is the predominant carotenoid in tomatoes, followed by a-carotene, b-carotene, g-carotene, and phytoene, as well as by several other minor carotenoids. Tomatoes and tomato-based foods have long been an important source of lycopene in the Western diet. There has been a growing interest in exploring the role of lycopene in the prevention of a variety of nutritional and health issues in humans, including some cancers and cardiovascular diseases. Recently, many case studies using cell cultures, animal models, and epidemiological investigations have shown a relationship between lycopene intake and a lowered risk of contracting some cancers and various chronic diseases. Increasingly, clinical evidence supports the role of lycopene as a nutrient with important health benefits, since it appears to provide protection against a broad range of epithelial cancers. The possibility that consumption of lycopene-rich foods may reduce the risk of such diseases has prompted numerous in-depth studies of the levels of lycopene in foods and of correlations between dietary lycopene and certain diseases. This monograph will serve as a reference for providing a better understanding of the role of lycopene in promoting health, and by encouraging a deeper understanding of approaches to a healthy diet and life.

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Though plant cells are separated by cell walls, cells maintain their identity as they are delimited by semi-permeable membranes that permit them to function as autonomous units. The flow of materials in and out of the cell is regulated by channels, transporters, pumps, and acquaporins in these membranes. The cytoplasm is sandwiched between two membranes: the plasma membrane, which forms the outer boundary of the cytoplasm, and the tonoplast or the vacuolar membrane which forms the inner boundary. Cell membranes serve several different functions: form boundaries and provide compartmentalization, site of chemical reactions catalyzed by membrane proteins, regulate the exchange of ions/compounds across the barrier, site of perception/transmission of signals (hormones), and act in cell-to-cell communication. The membrane functions are affected by different abiotic (biotic stress not discussed), nutritional, edaphic and mechanical stresses, which have been discussed in this volume in light of the recent literature

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It is necessary to integrate field data relevant to policy with a global overview with up-to-date information for synthesis into scenarios and a vision of how future research and development in agriculture can best help those who are most needy and have little access to productive resources. The overall task is a huge challenge for policy-makers and the agricultural research establishment. It is also of concern in teaching agricultural students to be able to respond to future challenges. This publication is an attempt to stimulate discussion on future options of research policy, suggesting changes of agricultural R&D for societal development in accordance with the Millennium Development Goals.

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To cope with the abiotic stress-induced osmotic problems, plants adapt by either increasing uptake of inorganic ions from the external solution, or by de novo synthesis of organic compatible solutes acting as osmolytes. Of the osmoregulants and protectants discussed in this volume, trehalose, fructans, ectoine and citrulline, which are generated in different species, in osmotically ineffective amounts, mitigate the stress effects on cells/plants and improve productivity. There are several pieces of encouraging research discussed in this volume showing significant improvement in stress tolerance and in turn productivity by involving genetic engineering techniques.

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Phenomenal progress has been made in our understanding of the several and diverse ways in which micronutrients alter or regulate the functioning of plants and produce a wide array of responses enabling quantitative and qualitative changes in plant yield. This book addresses biochemical and physiological roles of micronutrients in plants and the diverse ways in which they react to limitations in micronutrients supply, contributing to global constraints in crop production. The book is presented in two parts. Part I deals with roles of micronutrients and the changes induced in plants in response to their inadequate supply. Part II addresses the factors contributing to micronutrients deficiency, their diagnosis, evaluation and management through soil ? and plant ?based approaches.

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This book covers various aspects of information on bio-ecology, temporal and spatial distribution, key mortality factors, population dynamics and early warning system, host plant resistance, mechanism and inheritance of resistance, introgression of resistance genes from closely related wild relatives of crops, transgenics, molecular marker-assisted selection, bio-control agents including natural enemies and biopesticides, natural plant products, chemical control and insecticide resistance management, and integrated management of Heliothis/Helicoverpa. An attempt has been made to pinpoint the gaps in our knowledge of Heliothis/Helicoverpa management and identify the areas for future research thrusts. Considering the complexity of effectively managing Heliothis/Helicoverpa infestations, it is imperative that we follow an integrated approach. This integration will involve agronomic and cultural management, host plant resistance, transgenics, biological control and judicious use of chemical pesticides. Many poten

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This book is an essential knowledge base for both ecological restoration and management. Although tropical lakes are not identical, and therefore require individually developed and restoration and management practices; there are general principles in both restoration and management that can be derived from the case histories in this book and the limnological literature in general.

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The book begins with a chapter on Molecular Evolution and Phylogeny of mycorrhizas. Lucid discussions on cellular physiology, molecular genetics, and molecular regulation of nutrient exchange phenomenon in mycorrhizas form the core of this book. A comparative analysis of the molecular aspects of symbiosis and pathogenesis has been presented in detail. It also includes certain agriculturally useful aspects of disease control via mycorrhizas. Discussions on recent developments in molecular ecology of mycorrhizas, including most recently enunciated concepts such as ?nurse functions?, ?mycoheterotrophy? are provided in the book. Transformation, transgenics and genetic engineering of mycorrhizas is a unique and futuristic chapter. Applications of genetic engineering of mycorrhizas, as well as recently developed techniques of genetic transformation production of viable transgenic mycorrhizal fungi have been delineated. It will be useful to researchers/students involved in Microbiology, Molecular Biology, Plant Bio

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In Volume I of Insect Phenotypic Plasticity, the plasticity inherent in insects is documented. Phenotypically plastic traits include morphological, behavioral, and physiological characteristics. These environmentally induced differences can serve as the raw products upon which natural selection acts. Phenotypic plasticity in short deserves increased attention by those involved in studies on biological diversity and is of practical concern for agricultural and medical Entomology.

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Potato is the most significant non-cereal crop. Much attention has been paid to this commercially important crop. The aim of this volume is to capture the recent advances made in improving potatoes using traditional breeding methods as well as genetic engineering technology. The book provides a critical appraisal of the state-of-the-art finding on this crop.

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Since the first groundbreaking edition of Developments in Pressure-Sensitive Products was introduced in 1998, heavy research has resulted in substantial progress in the field. Fully updated and expanded to reflect this activity, Developments in Pressure-Sensitive Products, Second Edition provides a detailed overview of the entire range of pressure-sensitive products, both with and without adhesives. It explores the principles behind their design and manufacture along with a variety of applications in medicine, electronics, packaging, and protection.The book establishes the link between underlying theory and practical applications, exploring the physical, molecular, and chemical bases of PSPs while describing the manufacturing processes, end uses, and economic issues involved. This edition includes three new chapters: the first of these explains the new theory of pressure sensitivity considered as a process, illustrating the principles of polymer science governing PSP technology; the second discusses the crosslinking of acrylics, the most important domain in specialized products; and the third presents the latest developments in products based on plastomers, such as hydrogels. Additional coverage includes biological applications of PSPs, engineering problems of coating equipment, web finishing for plastic films, and confectioning.Offering cutting-edge information from the frontiers of research and industry, Developments in Pressure-Sensitive Products, Second Edition is an ideal reference to all aspects of pressure-sensitive technologies and materials.

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The discovery of new and previously unknown organisms that cause foodborne illness makes it essential for scientists, regulators, and those in the food industry to reconsider their traditional approaches to food preservation. A single source reference that can provide the latest practical information on how to deal with the range of probiotic health issues that have recently arisen would be invaluable to have. Probiotics in Food Safety and Human Health is that resource. It presents an in-depth characterization and diagnosis of probiotic strains and their mechanisms of action in humans, explains the role food applications have in the development of new products that guard against gastrointestinal diseases, and addresses the current regulatory environment. The material in each chapter is written in an accessible format by internationally renowned experts and includes citations from scientific literature. Highlights include a thorough discussion of probiotic issues such as pre- and postharvest food safety applications of probiotics, genetic engineering, and probiotic identification. The book also presents information on new regulations and emerging trends in the two major probiotics markets in the world, Europe and Japan. Unique in its depth and breadth of scope, Probiotics in Food Safety and Human Health provides vital information to those who need to be knowledgeable of the functional properties of foods aimed at improving human health.

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Polyphenol phytoestrogens – bioactives found in specific foods and beverages – impart antioxidant, phytoestrogenic, antiproliferative, and enzyme modulating activities within the human metabolic system. It is believed that these compounds protect against several forms of cancer, cardiovascular and neurodegenerative diseases, osteoporosis, and menopausal symptoms. While there has been a rise in polyphenol research over the past few years resulting from this discovery, there has not been a thorough, single source guide that synthesizes and explains the attained information – until now. Phytoestrogens in Functional Foods comprehensively details the scientific, technical, and practical aspects involved in the production, consumption, and safety of phytoestrogens in foods.The book is divided into five parts for easy reference. Section I, Production, introduces the topic of phytoestrogens and addresses the biosynthesis of polyphenol phytoestrogens in plants, and the chemistry and mechanism of action of phytoestrogens. Section II, Consumption, explains pharmacokinetics, body composition, and cell signaling. Section III, Risk and Benefit Analysis, examines reproductive hormones in females, hormone replacement therapy, and the benefits and risks associated with phytoestrogens. Section IV, Optimization and Utilization, discusses soy isoflavones and health, while Section V, Applications, explains wine antioxidants and phytoestrogens. While extensive investigation of these topics has led to many conflicting reports about their risks and benefits, this text provides answers and insight on the major questions regarding the core areas of polyphenol research.

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Lipids play an essential role in cell signaling and subcellular structure. Systematic analysis of the total lipid structure of a cell or organism, the lipodome, can reveal novel avenues of therapeutic intervention and diagnosis. This analysis is best modeled after the lessons learned from proteomics. With contributions from pioneering researchers from the US, Europe, Canada, Japan, and China, Functional Lipidomics introduces lipidomics, explores the current state of the field, and provides a comprehensive background for future groundbreaking work in this burgeoning field.The first book dedicated to the topic, Functional Lipidomics first defines and introduces the field before delving deeply into the methods, processes, analyses, and research aspects. The book uncovers the biosynthesis, metabolism, and function of fatty acids, acylglyerols, glycerophospholipids, sphingolipids, terpenes, and lipids that complex with proteins. Taking both academic and industrial perspectives, the contributors elaborate upon cutting-edge approaches to lipid analysis, diagnostic approaches using lipid and lipid-binding protein patterns, and the therapeutic significance of targeting proteins involved with the lipid signaling pathway. Functional Lipidomics elucidates state-of-the-art strategies and techniques that enable us to understand biochemical patterns related to disease states, develop new targets for drug design, and identify important markers of a developmental stage, pathological condition, or disease treatment.

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In the fiercely competitive pharmaceutical marketplace, your organization cannot afford to spend excess dollars developing drugs that will fail to get FDA approval or have profoundly poor characteristics. Biochips as Pathways to Drug Discovery takes a comprehensive look at how the industry faces these challenges, using new technologies such as biochips to reduce the cost of drug discovery and improve drug safety. The book explores the tools and skills required at each step of the discovery process when using biochips to determine biological outcomes.The authors provide an in-depth review of the clinical and pharmacogenomic relevance of biochips, ChIP-chip assays, and high-throughput approaches. They discuss how biochips are used to develop biomarkers in the drug discovery process, primarily for gene expression profiling and Single Nucleotide Polymorphism (SNP) analysis. The book includes coverage of experimental theory, quality control, clinical laboratory sampling considerations, database concepts, industrial laboratory design, and the analysis of the resultant large data sets. It discusses the application of biochips to the study of malaria, toxicogenomics, and SNPs, as well as intellectual property and market overviews. The book concludes with a comprehensive overview of how these chips are employed from early target discovery through preclinical toxicology and on through to pharmacogenomic and proof of concept studies in humans. Written in an easily accessible style, the breadth of coverage introduces the subject to those new to the field, while the depth of coverage forms a foundation for future work. The book gives you the knowledge required to leverage the technology into bona fide discoveries. Daniel E. Levy, editor of the Drug Discovery Series, is the founder of DEL BioPharma, a consulting service for drug discovery programs. He also maintains a blog that explores organic chemistry.

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Existing ERP systems are being used to support an increasing amount of critical e-business initiatives, even though this is far from their original purpose. While ERP can form a foundation for successfully meeting e-business needs, future success will be derived not only from a firm, supportive foundation, but from a solid e-business superstructure that guides your company through a value chain that has grown longer and more complex.ERP Optimization provides a technology-centric approach to leading your company through an e-transformation. It shows you how to leverage current investments in information systems while minimizing disruptions to the core business of the enterprise. Written in a business vernacular, the book effectively bridges the gap between technology and business strategy. The author takes you through the process of defining e-business goals and accessing and maximizing current systems capabilities. She details the steps required to assume a leadership position within an integrated business community and demonstrates how to support secure information exchanges with customer, suppliers,and partners.ERP alone is not enough to secure and maintain a superior position in today's economy, but it can provide the backbone and infrastructure of enterprise applications that are the necessary, essential prerequisites to conducting e-business. Whether you are an executive today, or hope to be one in the future, ERP Optimization gives you the tools to lead your organization successfully into the e-business world.

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The final volume of this series presents a synopsis of the curriculum that a typical Six Sigma program should follow. It differs from the preceding six volumes in that it is an implementation volume, therefore the information is geared towards helping readers formalize their own training. The book establishes the minimum requirements for the Six Sigma methodology and provides the body of knowledge needed for a successful and rewarding implementation of the Six Sigma processes.

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The classic nursery story of "Jack and the Beanstalk" reads like a business dream come true: risky deal promises great returns, is scorned by skeptics, and ultimately results in phenomenal growth and profits. In the business world, Jack's fairy-tale experience is mirrored in the experiences of a select group of companies. The common thread: larger-than-life growth accompanied by risk, obstacles, and incredible profits. And with growth becoming increasingly essential to creating and maintaining shareholder value, such stellar examples have much to teach the rest of us.Competitive forces never stop. Just when a company finds itself near the top of the growth curve, new competitors, and new competitive issues arise. Without a successful growth strategy, its stay at the top will be a short visit. While it's true that there is no permanent roadmap for growth, there are critical signposts along the way and some of them can be found in the stories of courage and innovation captured in Sustaining Corporate Growth: Harnessing Your Strategic Strengths.This book identifies the success factors that characterize the truly dominant market leaders. It defines the requirements for true critical competency and shows how to identify and keep them sustainable. It lays out a six step plan to winning competitively with core competencies and developing those that generate the greatest customer benefit. You get the inside scoop about what works, time and again, at globally admired companies. Through the stories of eight world-renowned companies that have conquered obstacles to achieve sustainable, long-term growth you understand what it takes to beat the odds. These unique, diverse stories reveal common keys to growth that transcend industry and geographic boundaries. The primary key? Identifying, nurturing, and harnessing a company's strategic strengths and making them the centerpiece of growth. Sustaining Corporate Growth: Harnessing Your Strategic Strengths describes the secrets of sustainable success at some of the world's best-known companies.

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Virtual Project Management: Software Solutions for Today and the Future explores the technical management issues involved in the revolutionary new way of building complex software intensive systems faster and cheaper by employing the power of distributed operations. The book examines the implementation issues that cut deep inside present day collocated engineering organizations and recommends practical and affordable actions to aid organizations seeking increased productivity through distributed operations.The demand for integrated solutions constructed from a combination of existing and newly developed software increases daily. Many organizations find themselves with shortages of the critical skills necessary to compete in many of these newly created markets. Employing virtual collaborative development provides a dramatic increase in a company's opportunities to successfully compete. Virtual collaboration provides a broader skill and product knowledge base coupled with a deeper pool of personnel to potentially employ. It removes two of the major barriers - company affiliation and physical location. Virtual Project Management: Software Solutions for Today and the Future focuses on critical characteristics underlying how work actually gets done in traditional collocated engineering environments. It examines the changes taking place on virtual projects through a series of anecdotes based on real project experiences. The book provides an 8 step practical and affordable plan that can be used as a framework in either setting up and executing a new virtual project, or in instituting improvements to a project that has drifted off course. Others have lived through the pain of learning lessons the hard way. You don't need to follow their path. The insights and solutions offered by Paul McMahon answer the questions virtual project leaders will be asking well into the 21st century.

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Tremendously versatile, basket securities have the potential to change the way money is managed. This book provides the proper definition of the basket security, a brief exploration of their true history, and powerful ways to exploit their advantages. The authors explore simple yet effective ways basket securities can be used in asset management strategies including trading the market, building a diversified core, or creating a thousand stock portfolio. They cover the broad array of currently available basket securities and discuss others that are on the horizon, what and when to buy and sell, and how to protect investments from market declines.

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The Radiologic Technology Clinical Manual is designed to guide students through all aspects of clinical training in the area of radiological sciences. This practical workbook contains student self-evaluation forms, course outlines, instructional objectives, and all the procedures and work assignments necessary for training students in the clinical side of radiologic technology. It can be used as a supplement to any radiologic sciences program.When used as part of an occupational training course in radiologic technology, the Radiologic Technology Clinical Manual will help students qualify for examination by the American Registry of Radiologic Technologists (ARRT). The book contains valuable record keeping materials for clinical experience hours, background on the profession as a whole, and evaluation forms for quarterly periods of clinical training. Time sheets, attendance forms, and clinical log forms are also included.

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John Funge introduces a new approach to creating autonomous characters. Cognitive modeling provides computer-animated characters with logic, reasoning, and planning skills. Individual chapters in the book provide concrete examples of advanced character animation, automated cinematography, and a real-time computer game. Source code, animations, images, and other resources are available at the book's website, listed below.

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Trends in Food Engineering presents a wide vision of food engineering, with an emphasis on topics vital to the food industry today. The first section deals with physical and sensory properties of food. The emphasis in these chapters is on structure-function relationships, food rheology, and the correlations between physicochemical and sensory data. The second section, on advances in food processing, includes recent developments in minimal preservation and thermal and nonthermal processing of foods. The book concludes with current topics in food engineering, including applied biotechnology, food additives, and functional properties of proteins.

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According to the FDA Quality System Regulations, manufacturers must ensure that "device packaging and shipping containers are designed and constructed to protect the device from alteration or damage during the customary conditions of processing, storage, handling, and distribution." As specific as this statement is, the FDA does not provide instructions on how to achieve their standards. Validating Medical Packaging demystifies the validation procedure for medical device packaging by providing specific examples and templates for creating and maintaining a validation file.About the author: Ronald Pilchik has over 30 years of experience in the healthcare manufacturing industry. As principal of the Techmark Group, he provided consulting services to diverse multinational manufacturers on selecting, developing, and validating medical packaging compatible with their sterilization requirements. He has been chairman of the healthcare packaging section of TAPPI, the packaging committee of HIMA, and a member of AAMI's ISO198 working group on packaging. Mr. Pilchik is program chairman of the HealthPack Conference Series on medical device packaging.

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Yeast Sugar Metabolism looks at the biomechanics, genetics, biotechnology and applications of yeast sugar. The yeast Saccharomyces cereisiae has played a central role in the evolution of microbiology biochemistry and genetics, in addition to its use of a technical microbe for the production of alcoholic beverages and leavening of dough.

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Economic literature is often too theoretical for engineers and policymakers to put into practical use, while scientific literature on the remediation of contaminated aquifers rarely considers costs and benefits. Written by a hydrogeologist and an economist, The Economics of Groundwater Remediation and Protection integrates economics and cost-benefit analysis tools with optimal protection and remediation strategies for groundwater resources.The book provides a thorough introduction of the concepts of groundwater flow and contaminant transport, and the basics of economic decision making techniques. It illustrates the types of risks and impacts caused by groundwater contamination, and the economic benefits of its remediation. The volume reviews a wide range of issues such as cost, implementation, and expectations of success for the latest remediation trends and techniques. The book shows how economic analysis can be used to determine how much we should pay for groundwater clean-up, and when spending too much - or too little - actually makes us all worse-off. The authors' step-by-step methodology for decision-making focuses on determining optimal remedial objectives, from containment to extensive cleanup, and the selection of least-cost alternatives. They use examples from their personal experience to illustrate the methodologies in action and put the issues into perspective.Combining the theoretical and practical aspects of science, policy, and economics, this book places the importance of groundwater remediation in the context of environmental economics, protection, and preservation. The Economics of Groundwater Remediation and Protection is also an excellent introduction to innovative solutions for funding remediation projects, education, and incentive programs, such as mitigation banking, land pollution credit schemes, and conservation credit alternatives.

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The end of the 20th century brought with it a revolution in molecular biology that culminated in advances such as the completion of the human genome. This has brought optimism to the fields of toxicology and environmental health, and the anticipation that molecular biomarkers might soon come of age and have a major impact on human and environmental health. Biomarker research is an area of current interest to scientists in a number of fields that are concerned with environmental exposure to pollutants and environmentally associated disease.Biomarkers of Environmentally Associated Disease: Technologies, Concepts, and Perspectives provides comprehensive coverage of the current status and future prospects of a field that will play a key role in emerging areas of public health and medicine. It focuses on the risk to human and environmental health of exposure to persistent organic pollutants, heavy metals, airborne toxics, environmental estrogens, and other environmental pollutants. This material will aid researchers in understanding, treating, and preventing environmentally induced disease.Validated molecular biomarkers have long been recognized as invaluable tools for identifying and preventing human disease. As biomarkers begin to be applied more widely, it is also important to assure that they are implemented ethically, with attention to the social and legal issues associated with their use. Biomarkers of Environmentally Associated Disease is an outstanding resource providing state-of-the-art information for the fields that encompass molecular biomarkers.

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