Search results for ""InterActions""

Note: The three volumes are not sequential but rather independent of each other and largely self-contained.Basic Matters is a first introduction to quantum mechanics that does not assume any prior knowledge of the subject. The emphasis is on the general structure as the necessary foundation of any understanding. Starting from the simplest quantum phenomenon, the Stern-Gerlach experiment with its choice between two discrete outcomes, and ending with one-dimensional continuous systems, the physical concepts and notions as well as the mathematical formalism of quantum mechanics are developed in successive, manageable steps. The presentation is modern inasmuch as the natural language of the trade - Dirac's kets and bras and so on - is introduced early, and the temporal evolution is dealt with in a picture-free manner, with Schrödinger's and Heisenberg's equations of motion side by side and on equal footing.The reader of Simple Systems is not expected to be familiar with the material in Basic Matters, but should have the minimal knowledge of a standard brief introduction to quantum mechanics with its typical emphasis on one-dimensional position wave functions. The step to Dirac's more abstract and much more powerful formalism is taken immediately, followed by reviews of quantum kinematics and quantum dynamics. The important standard examples (force-free motion, constant force, harmonic oscillator, hydrogen-like atoms) are then treated in considerable detail, whereby a nonstandard perspective is offered wherever it is deemed feasible and useful. A final chapter is devoted to approximation methods, from the Hellmann-Feynman theorem to the WKB quantization rule.Perturbed Evolution has a closer link to Simple Systems than that volume has to Basic Matters, but any reader familiar with the subject matter of a solid introduction to quantum mechanics - such as Dirac's formalism of kets and bras, Schrödinger's and Heisenberg's equations of motion, and the standard examples that can be treated exactly, with harmonic oscillators and hydrogen-like atoms among them - can cope with the somewhat advanced material of this volume. The basics of kinematics and dynamics are reviewed at the outset, including discussions of Bohr's principle of complementarity and Schwinger's quantum action principle. The Born series, the Lippmann-Schwinger equation, and Fermi's golden rule are recurring themes in the treatment of the central subject matter - the evolution in the presence of perturbing interactions for which there are no exact solutions as one has them for the standard examples in Simple Systems. The scattering by a localized potential is regarded as a perturbed evolution of a particular kind and is dealt with accordingly. The unique features of the scattering of indistinguishable quantum objects illustrate the nonclassical properties of bosons and fermions and prepare the groundwork for a discussion of multi-electron atoms.

Read more less

Note: The three volumes are not sequential but rather independent of each other and largely self-contained.Basic Matters is a first introduction to quantum mechanics that does not assume any prior knowledge of the subject. The emphasis is on the general structure as the necessary foundation of any understanding. Starting from the simplest quantum phenomenon, the Stern-Gerlach experiment with its choice between two discrete outcomes, and ending with one-dimensional continuous systems, the physical concepts and notions as well as the mathematical formalism of quantum mechanics are developed in successive, manageable steps. The presentation is modern inasmuch as the natural language of the trade - Dirac's kets and bras and so on - is introduced early, and the temporal evolution is dealt with in a picture-free manner, with Schrödinger's and Heisenberg's equations of motion side by side and on equal footing.The reader of Simple Systems is not expected to be familiar with the material in Basic Matters, but should have the minimal knowledge of a standard brief introduction to quantum mechanics with its typical emphasis on one-dimensional position wave functions. The step to Dirac's more abstract and much more powerful formalism is taken immediately, followed by reviews of quantum kinematics and quantum dynamics. The important standard examples (force-free motion, constant force, harmonic oscillator, hydrogen-like atoms) are then treated in considerable detail, whereby a nonstandard perspective is offered wherever it is deemed feasible and useful. A final chapter is devoted to approximation methods, from the Hellmann-Feynman theorem to the WKB quantization rule.Perturbed Evolution has a closer link to Simple Systems than that volume has to Basic Matters, but any reader familiar with the subject matter of a solid introduction to quantum mechanics - such as Dirac's formalism of kets and bras, Schrödinger's and Heisenberg's equations of motion, and the standard examples that can be treated exactly, with harmonic oscillators and hydrogen-like atoms among them - can cope with the somewhat advanced material of this volume. The basics of kinematics and dynamics are reviewed at the outset, including discussions of Bohr's principle of complementarity and Schwinger's quantum action principle. The Born series, the Lippmann-Schwinger equation, and Fermi's golden rule are recurring themes in the treatment of the central subject matter - the evolution in the presence of perturbing interactions for which there are no exact solutions as one has them for the standard examples in Simple Systems. The scattering by a localized potential is regarded as a perturbed evolution of a particular kind and is dealt with accordingly. The unique features of the scattering of indistinguishable quantum objects illustrate the nonclassical properties of bosons and fermions and prepare the groundwork for a discussion of multi-electron atoms.

Read more less

*Part of the 5-Volume Set 2022 Nautilus Book Award Gold Medal Winner: Ecology & Environment and Special Honors as Best of Anthology Volume 2 of the Kinship series revolves around the question of place-based relations: To what extent does crafting a deeper connection with the Earth’s bioregions reinvigorate a sense of kinship with the place-based beings, systems, and communities that mutually shape one another? We live in an astounding world of relations. We share these ties that bind with our fellow humans—and we share these relations with nonhuman beings as well. From the bacterium swimming in your belly to the trees exhaling the breath you breathe, this community of life is our kin—and, for many cultures around the world, being human is based upon this extended sense of kinship. Kinship: Belonging in a World of Relations is a lively series that explores our deep interconnections with the living world. The five Kinship volumes—Planet, Place, Partners, Persons, Practice—offer essays, interviews, poetry, and stories of solidarity, highlighting the interdependence that exists between humans and nonhuman beings. More than 70 contributors—including Robin Wall Kimmerer, Richard Powers, David Abram, J. Drew Lanham, and Sharon Blackie—invite readers into cosmologies, narratives, and everyday interactions that embrace a more-than-human world as worthy of our response and responsibility. Given the place-based circumstances of human evolution and culture, global consciousness may be too broad a scale of care. “Place,” Volume 2 of the Kinship series, addresses the bioregional, multispecies communities and landscapes within which we dwell. The essayists and poets in this volume take us around the world to a variety of distinctive places—from ethnobiologist Gary Paul Nabhan’s beloved and beleaguered sacred U.S.-Mexico borderlands, to Pacific islander and poet Craig Santos Perez’s ancestral shores, to writer Lisa María Madera’s “vibrant flow of kinship” in the equatorial Andes expressed in Pacha Mama’s constitutional rights in Ecuador. As Chippewa scholar-activist Melissa Nelson observes about kinning with place in her conversation with John Hausdoerffer: “Whether a desert mesa, a forested mountain, a windswept plain, or a crowded city—those places also participate in this serious play with raven cries, northern winds, car traffic, or coyote howls.” This volume reveals the ways in which playing in, tending to, and caring for place wraps us into a world of kinship. Proceeds from sales of Kinship benefit the nonprofit, non-partisan Center for Humans and Nature, which partners with some of the brightest minds to explore human responsibilities to each other and the more-than-human world. The Center brings together philosophers, ecologists, artists, political scientists, anthropologists, poets and economists, among others, to think creatively about a resilient future for the whole community of life.

Read more less

The most important work by a key figure in German thought, Helmuth Plessner’s Levels of Organic Life and the Human, originally published in 1928, appears here for the first time in English, accompanied by a substantial Introduction by J. M. Bernstein, after having served for decades as an influence on thinkers as diverse as Merleau-Ponty, Peter Berger, Habermas, and the new naturalists. The Levels, as it has long been known, draws on phenomenological, biological, and social scientific sources as part of a systematic account of nature, life, and human existence. The book considers non-living nature, plants, non-human animals, and human beings in turn as a sequence of increasingly complex modes of boundary dynamics—simply put, interactions between a thing’s insides and surrounding world. On Plessner’s unique account, living things are classed and analyzed by their “positionality,” or orientation to and within an environment. “Life” is thereby phenomenologically defined, and its universal yet internally variable features such as metabolism, reproduction, and death are explained. The approach provides a foundation not only for philosophical biology but philosophical anthropology as well. According to Plessner’s radical view, the human form of life is excentric—that is, the relation between body and environment is something to which humans themselves are positioned and can take a position. This “excentric positionality” enables human beings to take a stand outside the boundaries of their own body, a possibility with significant implications for knowledge, culture, religion, and technology. Plessner studied zoology and philosophy with Hans Driesch in the 1910s before embarking on a highly productive philosophical career. His work was initially obscured by the superficially similar views of Max Scheler and Martin Heidegger and by his forced exile during World War II. Only in recent decades, as scholarship has moved more squarely into engagement with issues like animality, embodiment, human dignity, social theory, the philosophy of technology, and the philosophy of nature, has the originality and depth of Plessner’s vision been appreciated. A powerful and sophisticated account of embodiment, the Levels shows, with reference both to science and to philosophy, how life can be seen on its own terms to establish its own boundaries, and how, from the standpoint of life, the human establishes itself in relation to the nonhuman. As such, the book is not merely a historical monument but a source for invigorating a range of vital current conversations around the animal, posthumanism, the material turn, and the biology and sociology of cognition. This modern philosophical classic, long-awaited in English translation, is a key book both historically and for today’s interest in understanding philosophy and social theory together with science, without reducing the former to the latter.

Read more less

Second harmonic generation (SHG) has a wide range of applications in today's technological era, including nonlinear optics, quantum optics, lasers, material science, medical science, biological imaging, and high-resolution optical microscopy. In the laser industry, for example, SHG is prudent to create wavelength-specific high-energy lasers. It is also used to measure ultra-short pulse width with autocorrelators. SHG is now indispensable as a spectroscopic imaging tool in applications, such as biophysical characterization of the plasma membrane, biological sensing, disease diagnostics, and investigations of biomolecular interactions at interfaces. Because of its non-destructive detection, ultrafast response, and polarization sensitivity, SHG is exploited to describe crystal structures and materials. The use of SHG to characterize two-dimensional (2D) material structures gives crucial insights into their physical properties, thereby promoting the development of the relevant basic research, leading to the investigation of the potential applications of those materials. Developments in SHG research hold promising potentials of a large class of materials, such as magnetic- and nonmagnetic layered materials, perovskites, antiferromagnetic oxides, II-VI and III-V semiconductors, and nanotubes, for a variety of technological applications. This book focuses on the process of modelling and simulations of the SHG phenomenon in the area of nonlinear and quantum optics. The first chapter provides a visualization of the scientific landscape of research in SHG using scientometric analysis from 1962 to 2020 based on Scopus database. This chapter gives new postgraduate students in the subject useful information on hot themes in SHG research and how they are related to one another. There is also a brief mention of multinational collaborative networks. The following four research chapters look at the SHG from a classical standpoint, using Maxwell's equations to describe the nonlinear optical interaction between the electromagnetic wave and the medium. Such interaction is treated quantum mechanically in the second section of the book, with the SHG process described using a propagating Hamiltonian. As such, the volume adequately describes the SHG from both the classical and quantum mechanical standpoints. This allows the postgraduate researchers, focusing on the nonlinear phenomena, resulting from light-matter interaction, to find the content useful. In the second part of this volume, readers are introduced to a full theoretical analysis of the quantum features generated in certain optical devices, such as a two-waveguide device working under the SHG and coupled waveguide arrays with the combined second- and third-order nonlinear effects. To be more specific, this part discusses how SHG-enabled devices might be a useful source of nonclassical light. This section remains relevant for postgraduate students commencing their studies in quantum optics, where the nonclassical phenomena, such as squeezing and entanglement, require a solid understanding of the underlying techniques, namely the phase space and the analytical perturbative methods.

Read more less

The most important work by a key figure in German thought, Helmuth Plessner’s Levels of Organic Life and the Human, originally published in 1928, appears here for the first time in English, accompanied by a substantial Introduction by J. M. Bernstein, after having served for decades as an influence on thinkers as diverse as Merleau-Ponty, Peter Berger, Habermas, and the new naturalists. The Levels, as it has long been known, draws on phenomenological, biological, and social scientific sources as part of a systematic account of nature, life, and human existence. The book considers non-living nature, plants, non-human animals, and human beings in turn as a sequence of increasingly complex modes of boundary dynamics—simply put, interactions between a thing’s insides and surrounding world. On Plessner’s unique account, living things are classed and analyzed by their “positionality,” or orientation to and within an environment. “Life” is thereby phenomenologically defined, and its universal yet internally variable features such as metabolism, reproduction, and death are explained. The approach provides a foundation not only for philosophical biology but philosophical anthropology as well. According to Plessner’s radical view, the human form of life is excentric—that is, the relation between body and environment is something to which humans themselves are positioned and can take a position. This “excentric positionality” enables human beings to take a stand outside the boundaries of their own body, a possibility with significant implications for knowledge, culture, religion, and technology. Plessner studied zoology and philosophy with Hans Driesch in the 1910s before embarking on a highly productive philosophical career. His work was initially obscured by the superficially similar views of Max Scheler and Martin Heidegger and by his forced exile during World War II. Only in recent decades, as scholarship has moved more squarely into engagement with issues like animality, embodiment, human dignity, social theory, the philosophy of technology, and the philosophy of nature, has the originality and depth of Plessner’s vision been appreciated. A powerful and sophisticated account of embodiment, the Levels shows, with reference both to science and to philosophy, how life can be seen on its own terms to establish its own boundaries, and how, from the standpoint of life, the human establishes itself in relation to the nonhuman. As such, the book is not merely a historical monument but a source for invigorating a range of vital current conversations around the animal, posthumanism, the material turn, and the biology and sociology of cognition. This modern philosophical classic, long-awaited in English translation, is a key book both historically and for today’s interest in understanding philosophy and social theory together with science, without reducing the former to the latter.

Read more less

Tiger Woods’s long descent into a personal and professional hell reached bottom in the early hours of Memorial Day in 2017. Woods’s DUI arrest that night came on the heels of a desperate spinal surgery, just weeks after he told close friends he might never play tournament golf again. His mug shot and alarming arrest video were painful to look at and, for Woods, a deep humiliation. The former paragon of discipline now found himself hopelessly lost and out of control, exposed for all the world to see. That episode could have marked the beginning of Tiger’s end. It proved to be the opposite. Instead of sinking beneath the public disgrace of drug abuse and the private despair of a battered and ailing body, Woods embarked on the long road to redeeming himself. In The Second Life of Tiger Woods, Michael Bamberger, who has covered Woods since the golfer was an amateur, draws upon his deep network of sources inside locker rooms, caddie yards, clubhouses, fitness trailers, and back offices to tell the true and inspiring story of the legend’s return. Packed with new information and graced by insight, Bamberger’s story reveals how this iconic athlete clawed his way back to the top. Here you’ll meet the people who have shaped and saved Tiger’s life. It’s a disparate group: a Florida police officer, an old friend from Tiger’s boyhood, his girlfriend, his manager, his caddie. You’ll go inside the ropes and see Tiger’s interactions with fellow pros, with broadcasters and rules officials and Tour executives, with legends young (Rory McIlroy) and old (Jack Nicklaus) and in between (Fred Couples). On the Sunday before Masters Sunday, you’ll join Tiger as he takes a long, slow, contemplative walk across Augusta National, and you’ll be with him again seven days later in the splendid isolation of the tee at thirteen, in the rain, his right foot slipping while he swings his driver at 120 miles per hour. This is an intimate portrait of a man who has spent his life in front of the camera but has done his best to make sure he was never really known. Here is Tiger, barefoot, in handcuffs, showing a police officer a witty and self-deprecating side of himself that the public never sees. Here is Tiger on the verge of tears with his children at the British Open. Here is Tiger trying to express his gratitude to his mother at a ceremony at the Rose Garden. In these pages, Tiger is funny, cold, generous, self-absorbed, inspiring—and real.The Second Life of Tiger Woods is not only the saga of an exceptional man but also a celebration of second chances. Being rich and famous had nothing to do with Woods’s return. Instead, readers will see him apply his intelligence, pride, and enormous capacity for work to the problems at hand. Bamberger’s bracingly honest book is about what Tiger Woods did, and about what any of us can do, when we face our demons head-on.

Read more less

How do we think of ourselves as poets? How does our race, our home(s), and our cultural heritage, shape our sense of belonging, our ways of seeing or experiencing the world? How can we learn from and offer support to each other? State of Play brings together conversations between an international line-up of poets, taking place over the course of a year, to offer rich insights into these questions and the ways a life lived in many places can invigorate one’s writing. With themes ranging from the sense of home and racialised expectations, to community and language, as well as the process of writing poetry, these creative discussions delve into the complexities and diversity of identity in the days of global citizenship and cultural diaspora.‘Multiple yet singular, the conversations here reveal the complexities of poetic language as a space of becoming rather than being, of identities sharply focusing under the weight of plurality, the forces of migration and the long tethers of home and empire. This book makes a critical intervention in the shaping of diasporic writing, turns us away from the outworn frameworks to demand bolder and more imaginative ways of reading. Let these conversations begin urgent ones elsewhere about how language is made and how it remakes us as global subjects speaking together.’ —Prof. Sandeep Parmar, Professor of English Literature, University of Liverpool and Founder of Ledbury Critics of Colour.‘State of Play reminds us of the global reach of English-language poetry and poetics, whose production is not limited to the predominantly white Anglophone countries of the so-called West and reminds us of the ongoing legacies of British colonialism underlying even such seemingly neutral concepts as home, everyday life, and poetics.’ —Prof. Dorothy Wang, author of Thinking Its Presence: Form, Race, and Subjectivity in Contemporary Asian American Poetry & convenor/co-founder of Race and Poetry and Poetics in the UK (RAPAPUK)‘Giving voice to a diverse and multi-generational choir of distinctive voices, this anthology offers rare and intimate insights into the creative challenges of writing poetry now and the vital importance of dialogue as a free space for the play of ideas and critical thinking.’ —Prof. Susheila Nasta, Founder of Wasafiri, Magazine of International Contemporary Writing‘State of Play draws together a sparky and inspiring array of conversations between East and Southeast Asian poets situated across continents and borders. The different interactions are characterised by their commitment to exchange and reciprocity even where the poets meet for the first time only through the medium of these conversations. Editors Jennifer Wong and Eddie Tay have done a superb job of bringing together a rich spectrum of topics including nomadism, childhood, diaspora, race, belonging, the question of what it is to be creative, and all-important issues of language-choice and self-translation. I wager that no reader interested in poetry will not find excitement in this vibrant anthology.’ —Prof. Elleke Boehmer, Professor of World Literature in English, University of Oxford

Read more less

According to the President’s Council on Fitness, Sports & Nutrition, “If exercise could be packaged into a pill, it would be the single most widely prescribed and beneficial medicine in the nation.” Yet the incorporation of physical activity into a regular routine proves difficult for many. Bringing together a field of experts, Doing Exercise Psychology uses applied theories alongside authentic client interactions to address the challenging psychological components of physical activity. Doing Exercise Psychology helps students understand how to build connections with individual clients, strengthen the professional relationship through listening, and understand clients’ needs. The text features diverse topics, bridging health psychology and exercise psychology and demonstrating the increasingly important role of physical activity in overall wellness and health. The first chapter is devoted to the development of mindfulness as a practitioner, while another addresses the difficulties professionals encounter with their own inactivity, encouraging self-reflection in order to be more helpful and open with clients. A key feature of many chapters in Doing Exercise Psychology is the in-the-trenches dialogue between practitioner and client, accompanied by follow-up commentary on what went right and what went wrong in particular sessions. Through these real-world scenarios, students will witness firsthand the methods that are most effective in communicating with clients. The text also explores complex questions such as these: • What are the implications and consequences of using exercise as a component of psychological therapies? • How can practitioners help clients with impaired movement abilities as a result of chronic conditions or illness embrace physical activity as part of their therapy or their lives? • How can exercise be incorporated in therapies to change nutrition, smoking, and alcohol habits? • Why are some exercise protocols that are extremely effective for some but not for others? • How can relationships, interrelatedness, and attunement to others be vehicles for healthy change in whatever kind of therapy is being done? The book is arranged so that information flows progressively, covering major themes early and then applying them to the field. Part I introduces the relationship-building motif by covering the variety of relationships that one might find in exercise and physical activity settings. Part II addresses specific conditions and behavior change, with suggestions for encouraging activity in those who are also working to quit smoking, reduce alcohol consumption, or modify their nutrition habits. Part III deals directly with chronic and major medical conditions that professionals will contend with on a regular basis, including cancer, heart disease, and multiple sclerosis. Part IV delves into the dark side of exercise, such as overtraining, exercise dependence, and eating disorders. A growing and exciting area of study, exercise psychology covers all the psychosocial, intra- and interpersonal, and cultural variables that come into play when people get together and exercise. Students and practitioners who work with individuals in exercise settings will find Doing Exercise Psychology a vital resource to refer to repeatedly in their practice.

Read more less

Children's experiences and well-being in their earliest years underpin and highly influence their future development and learning. Drawing on research with parents, children and a range of professionals in the early childhood field, this book considers how well-being is interpreted in the early childhood field. It includes snapshots of what our youngest children think about their well-being, and examines external environmental contexts that impact on well-being.The book raises a number of important issues and clarifies priorities that need to be kept at the forefront of practice and provision, such as the fundamental importance of prioritizing children and families' socio-cultural contexts, addressing inequalities and developing a listening culture. Importantly, there is also focus on appropriate pedagogical approaches and aspects of practice that support children's well-being in early childhood settings, such as adult-child relationships, quality interactions, physical play and creative expression. The book also highlights the inseparability of adults' and children's well-being and therefore the need to consider contexts that enhance the potential for parents and practitioners to experience well-being.For all students and practitioners who want to put young children's well-being at the forefront of their practice this is a fascinating, thought provoking and illuminating read.Contributors: Deborah Albon, Mary Dickins, Melian Mansfield, Penny Holland, Micky LeVoguer, Penny Mukherji, Jasmine Pasch, Linda Pound, Judy Stevenson"This book is a timely reminder that young children have a right to be listened to. Wellbeing as a concept is redefined using the voices of children, parents and practitioners. Important questions are raised about the cost to individuals and society if this is not taken seriously."Dilys Wilson, Senior Lecturer in Early Childhood Studies at Middlesex University, UK"This text brings together research literature, theoretical understanding and practical application. The book captures the essence of early childhood and provides a dialogue and debate of holistically challenging well-being for all. This is a book to be treasured."Dr Lesley Curtis, Headteacher/Head of Centre, Everton Nursery School and Family Centre"This book is an essential discussion and authoritative account of the explorations and research outcomes of the LMU/NCB project 'Talking about well-being in early childhood'. The book represents multi-faceted perspectives about children's wellbeing that underpin the values and principles of inclusion, understanding that children are citizens with personhood and rights."Estelle Martin, Anglia Ruskin University, UK"This book is based on a deep and honest respect for young children and the adults who work and play with them and it illustrates with passion and insight the ways in which emotional and physical well-being are built on positive relationships and connections between people."Helen Moylett, Early Years Consultant and writer"This book opens up the way for future analysis of how society can become more at ease with itself so that the unwitting consequences of deeply embedded institutional discrimination, intolerance, negative assumptions, expectations and judgements are removed from young children's lives."Jane Lane (advocate worker for racial equality in the early years)

Read more less

Modularization A practical, hands-on guide to offsite preassembly, beginning with the project as just a concept gleam in the CEO’s eye and winding all the way through implementation at the construction site. Modularization is a philosophy change! And along with that change, comes the need to understand the implementation requirements and project mindset adjustments that impact and influence all aspects of the modular project. To accomplish this, the book provides a complete (from beginning to end) identification and evaluation of the differences that make a modular project unique, starting with the very basics in terms of definitions and setting the groundwork of expectations by identifying benefits and challenges. Then, because the journey is as important as the destination, the reader is guided through the various project phases in a manner that reflects how they would be addressed in the workplace. From the very earliest identification of concepts, through early assessment and selection of the optimal choice to be finally carried into detailed design, the reader is acquainted with each phase of the development process, including explanations and relevant suggestions for many of the questions and issues that typically come up. A perfect reference for professional and technical leaders when developing the early, critical planning phases of modular projects, this guide offers useful examples and details on the fundamentals required to get a modular project started correctly and keep it on track. And, for those whom this is not their first foray into modular project management, this guide includes suggestions, examples, and/or lessons learned to make the subsequent module projects easier to implement. Recognized industry experts Michael Kluck and Dr. Jin Ouk Choi have authored this guide to modularization that is ideal for owners, contractors, project management, engineers, project controls, and procurement—in fact, anyone interested in improving current construction project management practices. In addition, its thought-provoking examples and project case studies provide the perfect platform for its instructional use in teaching modular concepts. Written from the perspective of both the Client/Owner and the EPC Contractor, this guide provides useful information needed for initial project management setup and technical details useful to working functional groups within the project. As such, it is truly a universal guide that can provide personnel at all levels within the project with the information needed to make project implementation more seamless. This book is written in terms of the large-scale industrial modularization project, but the steps and process are equally applicable to small-scale projects and projects outside the industrial construction realm. Some of the topics covered in this guide include: The basics (to set a basis for major topic presentations) Module configurations (“good, bad, and ugly”) A deep dive into modularization business case Module team and project interactions Module execution planning and timing Success factors, pitfalls and avoidance A walk through the “module project” A modular project case exercise – tying it all together Standardization – the next step What the future holds

Read more less

Understand Consumer Psychology to Drive Profits and GrowthWant to know exactly what’s driving your customer's behavior? NOW YOU CAN!The Customer Service Solution explains how consumers perceive services and shows you how toenhance the customer experience--every time.In this economic climate, the customer service experience is more critical than ever. Most leading service firms advocate the TLC mantra: Think Like a Customer. That's a good practice, but first you have to understand what your customer is thinking and feeling. Today's business leaders cannot afford to neglect the psychological principles that govern customer satisfaction and long-term loyalty.What are the factors that really determine customer satisfaction? Two of the nation's leading authorities on service psychology, Sriram Dasu and Richard Chase, have written this groundbreaking guide that identifies and demystifies the psychological triggers behind customer behavior. You'll go where customer satisfaction surveys, mystery shoppers, and focus groups can't--and learn exactlywhy customers respond and behave the way they do.With findings drawn from behavioral science research, this book provides all the tools you need to evaluate your current service platforms and design future strategies to enhance customer perceptions positively and drive your sales.The Customer Service Solution illustrates whyeven companies with high levels of satisfaction are missing tremendous opportunities by neglecting the emotional elements that govern consumer interactions.This book will show you how to: Shape and manage customer perceptions Understand implicit versus explicit outcomes Develop the roles of control and choiceamong buyers Design emotionally intelligent processes Build trust among customers Whatever your business may be--healthcare, hospitality, financial services, e-commerce, and more--this book is an essential tool to help you increase profits by leveraging your company's customer experience.PRAISE FOR THE CUSTOMER SERVICE SOLUTION:"Harnessing the power of emotions will help to drive an exceptional customer experience creating customers for life to help your business thrive. Finally, a guide tohelp us better understand how to do this." -- James Merlino, MD, Chief Experience Officer, Cleveland Clinic"Required reading for anyone designing a service encounter." -- James Heskett, Professor Emeritus, Harvard Business School, coauthor of The Service Profit Chain and Service Future"I have always known that our customers shop with us because they want to, not because they have to. How to make them want to is the secret that this great bookunlocks." -- Kevin Davis, President and CEO, Bristol Farms"[Dasu and Chase] share easy-to-understand ideas and guidance to operations managers who typically do not think about the psychology of customers in designing their services." -- Mary Jo Bitner, PhD, Professor andExecutive Director, Center for Services Leadership, W. P. Carey School, Arizona State University"Dasu and Chase provide an excellent set of ideas for delivering emotional customer service experiences through systems and operations." -- Rodolfo Medina, Vice President, Marketing & Commercial, Rock in Rio"This book provides valuable insights to managing and molding the customer's emotional journey, leading to ultimate satisfaction and sustainable loyalty." -- Ali V. Kasikci, Regional Managing Director, Orient-Express

Read more less

AComprehensive Guide to Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) begins by describing the general characteristics, classification, pharmacokinetics, pharmacodynamics, clinical uses and adverse effects of NSAIDs. The adverse effects of NSAIDs, drug interactions and their clinical applications in neurological diseases, headaches, and cerebrovascular diseases are discussed. These drugs are also often used in dermatology, especially in the treatment of dermatosis. Extensive information concerning NSAIDs and dermatological diseases is provided. A broad perspective on the role of NSAIDs in infectious diseases is also provided. The next chapter discusses findings concerning the effects of NSAIDs on bone and tendon healing, together with cellular and molecular factors. The authors suggest that NSAIDs may be a risk factor for tissue healing. Diclofenac sodium (DS), widely used in urology clinics, exhibits dose-dependent side effects on various systems. This chapter suggests that nanoparticle technology can be applied to the oral form of DS in order to reduce its side-effects. The effects of NSAIDs on the reproductive systems of both sexes are also evaluated. Both genders make extensive use of NSAIDs during infertility treatment. Another chapter focuses on how DS affects spermatogenesis. The authors suggest that DS causes histopathological changes in the testes by disrupting the nutrition of testicular cells and impairing complete testis functions. Men wishing to have children should therefore use this drug with caution. The authors also review the effects of NSAIDs on prostatitis, benign prostatic hyperplasia and prostate cancer. In the following chapter, the authors examine the role of NSAIDs in gynaecology and obstetrics. Advances in the use of NSAIDs and melatonin in reproductive medicine for both sexes are discussed. The authors describe the biological roles of NSAIDs and melatonin in human reproduction, diseases, pregnancy, and assisted reproductive treatment. The subsequent chapter highlights the side-effects of NSAIDs on the gastrointestinal system. This book goes on to assess how DS affects the nervous system in the light of molecular and cellular analysis. The authors first explore the dose-dependent effects of DS on the nervous system. They then examine the potential neuroprotective / neurotoxic effects of DS on the nervous system, including the spinal cord, brain, cerebellum and peripheral nerves. The effects of DS on the adult hippocampus are assessed based on experimental studies. The purpose of this section is to highlight the relationship between oxidative stresses and the role of antioxidants in reducing DS toxicity. The importance of melatonin administration against pre- and postnatal DS toxicity in the nervous system is evaluated in several chapters. Recent findings suggest that prenatal exposure to NSAIDs causes an alteration in the morphology of optic nerve fibres based on stereological, histological and electron microscopic analysis. The authors evaluate histomorphometric results from light and electron microscopic analysis of the effects of prenatal DS exposure on male fertility. Numerous studies have shown that all elements of the male system are affected by this exposure. Lastly, the authors specifically focus on Sertoli cells and suggest that prenatal DS exposure produces toxic effects on Sertoli cell morphology.

Read more less

Ready to master the medication process? Tap into the go-to resource for nursing pharmacology basics, with the fully updated new fifth edition of Pharmacology Made Incredibly Easy!®. Offering clear, concise descriptions of crucial nursing pharmacology concepts and procedures, this easy-to-follow, colorfully illustrated guide offers step-by-step guidance so to can grasp the fundamentals in enjoyable Incredibly Easy style. From initial assessment to safe medication administration and patient care plans, this is the perfect supplement to class materials, offering solid preparation for NCLEX®, as well as a handy refresher for experienced nurses. Learn the ins and outs of nursing pharmacology care, with the latest data and protocols: NEW chapters on patient education, sensory drugs, and dermatologic drugs NEW chapter on medication safety, including abbreviations to avoid and a review of dosage calculations NEW content on current approved medications and dosages, and expected versus adverse effects NEW content on emergency drugs, herbs/supplements, immunization schedule, and more Hundreds of colorful diagrams, drawings, and charts that illustrate core concepts, with easy-to-retain definitions and clear direction on administering drugs; drug distribution, absorption, and metabolism; drug classes and their uses; and potential drug interactions Quick-scan outline format offers up-to-date guidance on areas including: Nursing pharmacology fundamentals Concepts of pharmacokinetics, pharmacodynamics, and pharmacotherapeutics Pain drugs, autonomic nervous system drugs, neurologic and neuromuscular drugs Psychotherapeutic, anti-infective, anti-inflammatory, anti-allergy, and immunosuppressant drugs Antineoplastic drugs, drugs for fluid and electrolyte balance Ways a drug may affect patients of different ages and other warnings Content reflects the NCSBN Clinical Judgment Measurement Model – guidance from initial assessment to evaluating outcomes “Practice Makes Perfect” end-of-book practice exam – approximately 100 new NCLEX®-style questions, to increase your exam confidence Chapter features include: Prototype pro – Actions, indications, and nursing considerations for common prototype drugs A three-step process is provided throughout the chapters to help you care for individuals taking commonly prescribed medications Pharm function – Explains and illustrates how drugs act in the body, and addresses how to recognize and treat adverse reactions Before you give that drug – Warnings to consider before you administer a drug Education edge – Information to share with your patient Black Box Warnings boxes draw attention to life-threatening concerns Lifespan Lightbulb boxes highlight information about how a drug or drug class may affect patients of different ages Quick quiz – End-of-chapter questions with answers/explanations, to help you remember the essentials Nurse Joy and Jake illustrated characters offer tips and insights throughout About the Clinical Editors Cherie R. Rebar, PhD, MBA, RN, CNE, CNECI, COI, FAADN, is a Professor of Nursing at Wittenberg University in Springfield, OhioNicole Heimgartner, DNP, MSN, RN, CNE, CNECI, COI, is a Nursing Faculty member at Galen College of Nursing in Louisville, Kentucky Carolyn Gersch, PhD, MSN, RN, CNE, is a Professor of Practice in the Nursing Program at Wittenberg University in Springfield, Ohio

Read more less

Singing and Teaching Singing: A Holistic Approach to Classical Voice, Fourth Edition continues to be a beloved resource for singers and their teachers, speech-language pathologists, and laryngologists and an adopted text for instructors and students in voice, singing, and performing arts courses. Janice L. Chapman is able to draw on her experiences as a singer with some of the world's leading opera companies to present a teaching technique specifically focusing on voice in the areas of classical and opera singing. Interspersed with the concepts and components of Chapman's methods are vignettes from her life and career, animated by her conversational and vibrant style to guide (and entertain) the reader through the book in a step-by-step fashion. The philosophy of teaching presented combines three main facets: Holistic, Physiological, and Incremental. The Holistic segment emphasizes that the act of singing involves the whole person (i.e., body, mind, spirit, emotion, and voice); the Physiological segment stresses anatomy, muscular function, and effects of muscular interactions so that students and teachers alike can understand and visualize the functional workings of the torso, larynx, and the vocal tract and their impact on good singing practices; and the Incremental section shows that the act of singing and the teaching of singing can be broken down into manageable components that have a natural hierarchy that eventually interact and interlock. This teaching model provides a framework to master one element at a time, with the resulting effect of a complete and integrated mastery of technique. Chapman recommends this framework for rehabilitative work with the dysfunctional singer, for working with the developing singer, and for the ongoing development and maintenance of the technically able professional singer. New to the Fourth Edition: * New editor and co-author, Ron Morris, BSpThy (Hons); MMusStud (Voice), MSPAA, MASA (CC), PhD * The addition of completely new chapters on Laryngeal Registration, Vocal Acoustics and Acoustic Registration * Clarifications and exercises by Dr. Ron Morris on the use of the Accent Method breathing as a highly effective remedial and training technique * Expanded and updated information on Breathing and Support, Vocal Acoustics, Registers (Laryngeal and Acoustic), Teaching and Learning, Hearing and Singing, and Manual Therapy * Exercises have been significantly expanded and now are contained in a chapter of their own, which includes some information on lesson structure and practice * Significant updates reflect the current state of research and the latest advances in voice science and pedagogy have been referenced throughout * A new glossary has been added for ease of reading and clarification of pedagogical terms used in the text Key Features: * Case studies * Evidence- based and practical examples * Exercises * Contributions from some of the world's best-known voice professionals * Highly readable writing style suitable for teachers of singing and singers at all levels * A PluralPlus companion website with supplemental videos that demonstrate some of the exercises from the teaching model

Read more less

‘A simply outstanding book’ ‘Astonishing’ ‘[A] rich treasure-trove of photographs of objects’ ‘The book truly is a delight, and is a ‘book of the ancestors’ in a very real sense.’ ‘Highly recommended.’ - Sacred Hoop Magazine, March 2022 Stonehenge is one of the best known, but most misunderstood, monuments in the world. Contrary to common belief, it was not a static, unchanging structure built by shadowy figures or druids. Rather it represents the cumulative achievement of numerous generations who were woven into a complex and widespread network of cultural interactions, environmental change and belief systems. This publication, which accompanies the first exhibition about Stonehenge ever staged in London, uses the monument as a gateway to explore the communities and civilisations active at the time of its construction and beyond, between 4,000 and 1,000 BCE. Recent archaeological findings regarding the origin of Stonehenge’s striking ‘bluestones’ have reignited interest in this ancient wonder, the people who built it and the beliefs they held. Through the ‘iconic’ structure, spectacular objects of precious and exotic material and more humble, personal objects, authors Duncan Garrow and Neil Wilkin examine the dramatic cultural and societal shifts that characterised the world of Stonehenge, including the introduction of farming and development of metalworking. Covering a period of thousands of years, the publication traces the appearance of the first monuments in the landscape of Britain around 4,000 BCE, the arrival of the bluestones from the Preseli Hills in Pembrokeshire 1,000 years later, all the way up to a remarkable era of cross-Channel connectivity and trade between 1,500 and 800 BCE. Through a new study of the enigmatic and beautiful objects made and circulated during the age of Stonehenge, connections are charted in the shared religious practices and beliefs of communities from across Britain, Ireland and continental Europe. The presence of other stone and wooden circles hundreds of miles from Salisbury Plain – including Seahenge, discovered on a beach in Norfolk in 1998 – is further evidence of these shared ways of thinking. At a critical moment in the narrative of Stonehenge, around 2,500 BCE, the significance of the cosmos and the heavens expressed through the construction of stone circles and megalithic passage tombs began to wane and portable objects gained increasing importance. This key transformation is demonstrated by a highlight object from Germany: the Nebra Sky Disc, a bronze disc inlaid with gold symbols believed to represent the sun, a crescent moon and the Pleiades constellation. More modest items found in tombs, burials and settlements are no less important in shedding light on the development of ideas relating to identity, religious practices, and relationships between the living and dead. Monuments such as Stonehenge cannot be understood in isolation. Stonehenge was not always a static, monolithic structure: over generations it was adapted and added to by communities that changed and developed the landscape on which it still stands today.

Read more less

This brilliantly concise history of the Pacific Ocean nevertheless succeeds in examining both the indigenous presence on ocean's islands and Western control or influence over the its islands and shores. There is a particular focus on the period from the 1530s to 1890 with its greater Western coastal and oceanic presence in the Pacific, beginning with the Spanish takeover of the coasts of modern Central America, Colombia, Ecuador and Peru, and continuing with the Spaniards in the Philippines. There is also an emphasis on the very different physical and human environments of the four quadrants of the Pacific - the north-east, the north-west, the south-east and the south-west - and of the 'coastal' islands, that is the Aleutians, Japan and New Zealand, and continental coastlines. The focus is always on the interactions of Japan, California, Peru, Australia and other territories with the ocean, notably in terms of trade, migration and fishing.Black looks first at the geology, currents, winds and physical make-up of the Pacific, then the region's indigenous inhabitants to 1520. He describes the Pacific before the arrival of Europeans, its history of settlement, navigation methods and religious practices.From Easter Island, the focus shifts to European voyages, from Magellan to Cook and Tasman, the problems they faced, not least the sheer scale of the ocean. Black looks at the impact of these voyages on local people, including the Russians in the Aleutian Islands. Outside control of the region grew from 1788 to 1898. The British laid claim to Australia and America to the Phillipines. Western economic and political impact manifested in sandalwood and gold rushes, and the coming of steamships accelerated this impact. Territorial claims spread through Willis, Perry and the Americans, including to Hawaii. Black looks at the Maori wars in New Zealand and the War of the Pacific on the South American coast. Christian missionary activity increased, and Gaugin offered a different vision of the Pacific. 1899 to 1945 marked the struggle of empires: the rise of Japan as an oceanic power, and the Second World War in the Pacific as a critical moment in world history. Oil-powered ships ushered in the American Age, from 1945 to 2015, bringing the end of the British Pacific. France had a continued role, in Tahiti and New Caledonia, but America had become the dominant presence. Black explores the political, economic and cultural impacts of, for example, Polynesians attending universities in America and Australasia; the spread of rugby; and relatively little international tension, although some domestic pressures remained, including instability in Papua New Guinea and Fiji. The book ends with a look at the Pacific's future: pressures from industrial fishing, pollution and climate change; the rise of drug smuggling; greater Chinese influence leading to conflict with America and Australasia - the Pacific is once again on the frontline of military planning. But the Pacific's future also includes tourism, from Acapulco to Hawaii, and from Tahiti to Cairns.

Read more less

Recent discoveries have given rise to a new class of electronics known as "spin electronics" or "spintronics," which uses the electron spin rather than its charge to create polarized currents. Spintronics is currently experiencing an extraordinary development with the manufacture of nanoscale devices based on ferromagnetic materials and semiconductors. Their applications are numerous, ranging from recording, electronics, and optoelectronics to quantum information. Spintronics is a new generation of electronics that has brought and continues to bring a lot of progress to information storage; this is due to the discovery of new materials with new functionalities and multiple applications. The discovery of giant magnetoresistance (GMR) in 1988 by Albert Fert and Peter GrÃ"nberg (receiver of the Nobel Prize in Physics in 2007) is considered a starting point of spintronics. GMR is based on the variation of the electric current in the presence of a magnetic field. The spintronics has made important contributions to the miniaturization desired for electronics; it uses nanometric components for processing and storing information. However, the limits of miniaturization on a nanometric scale are known, and it is imperative to develop new ways and new materials to exceed those limits. The most desired properties for these materials are high spin polarization, modular magnetic properties by an electric field and a long lifetime of the spin polarization. Among the new promising materials, we cite the following: Diluted magnetic semiconductors, which give new magnetic properties of conventional semiconductors, functional oxides (including the semi-metals and multiferroic metals) and organic semiconductors. The main theoretical challenge in this area is to understand how the macroscopic magnetic behavior observed results from interactions of a large number of degrees of microscopic freedom. In these systems the disorder is an essential parameter of magnetic phenomena, and due to random locations of impurity atoms it can lead to a total physical difference from the observed absence. There has been considerable recent advances in the design of these materials as diluted magnetic semiconductors (DMS, or diluted magnetic semiconductors), and a number of semiconductors were investigated as II-VI group and III-V group doped compounds, with transition metals substituting their original cations. There are several different theoretical approaches to study these magnetic materials. The ab-initio approach starts from the Schrödinger equation to simulate a given material. Such an approach is essential to determine the parameters and microscopic properties of such a system. In this book, the authors analyzed the electronic structure of magnetic semiconductors diluted in the case of ZnO, GaN, SnO2, TiO2, MgH2, EuO and EuN doped RENs (RE=GdN, DyN and HoN). The authors focused on magnetic, optical and exchange mechanisms which control the ferromagnetism in these systems. The purpose of this book is to propose some ideas to answer the most important question in material science for semiconductor spintronics, primarily considering how room-temperature ferromagnetism in DMS can be realized. Additionally, the correlation between first principle and experimental design to see how properties of yet-to-be-synthesized materials can be predicted is discussed.

Read more less

Ready to master the medication process? Tap into the go-to resource for nursing pharmacology basics, with the fully updated new fifth edition of Pharmacology Made Incredibly Easy!®. Offering clear, concise descriptions of crucial nursing pharmacology concepts and procedures, this easy-to-follow, colorfully illustrated guide offers step-by-step guidance so to can grasp the fundamentals in enjoyable Incredibly Easy style. From initial assessment to safe medication administration and patient care plans, this is the perfect supplement to class materials, offering solid preparation for NCLEX®, as well as a handy refresher for experienced nurses. Learn the ins and outs of nursing pharmacology care, with the latest data and protocols: NEW chapters on patient education, sensory drugs, and dermatologic drugs NEW chapter on medication safety, including abbreviations to avoid and a review of dosage calculations NEW content on current approved medications, and dosages, and expected versus adverse effects NEW content on emergency drugs, herbs/supplements, immunization schedule, and more Hundreds of colorful diagrams, drawings, and charts that illustrate core concepts, with easy-to-retain definitions and clear direction on administering drugs; drug distribution, absorption, and metabolism; drug classes and their uses; and potential drug interactions Quick-scan outline format offers up-to-date guidance on areas including: Nursing pharmacology fundamentals Concepts of pharmacokinetics, pharmacodynamics, and pharmacotherapeutics Pain drugs, autonomic nervous system drugs, neurologic and neuromuscular drugs Psychotherapeutic, anti-infective, anti-inflammatory, anti-allergy, and immunosuppressant drugs Antineoplastic drugs, drugs for fluid and electrolyte balance Ways a drug may affect patients of different ages and other warnings Content reflects the NCSBN Clinical Judgment Measurement Model – guidance from initial assessment to evaluating outcomes “Practice Makes Perfect” end-of-book practice exam – approximately 100 new NCLEX®-style questions, to increase your exam confidence Chapter features include: Prototype pro – Actions, indications, and nursing considerations for common prototype drugs A three-step process is provided throughout the chapters to help you care for individuals taking commonly prescribed medications Pharm function – Explains and illustrates how drugs act in the body, and addresses how to recognize and treat adverse reactions Before you give that drug – Warnings to consider before you administer a drug Education edge – Information to share with your patient Black Box Warnings boxes draw attention to life-threatening concerns Lifespan Lightbulb boxes highlight information about how a drug or drug class may affect patients of different ages Quick quiz – End-of-chapter questions with answers/explanations, to help you remember the essentials Nurse Joy and Jake illustrated characters offer tips and insights throughout About the Clinical Editors Cherie R. Rebar, PhD, MBA, RN, CNE, CNECI, COI, FAADN, is a Professor of Nursing at Wittenberg University in Springfield, OhioNicole Heimgartner, DNP, MSN, RN, CNE, CNECI, COI, is a Nursing Faculty member at Galen College of Nursing in Louisville, Kentucky Carolyn Gersch, PhD, MSN, RN, CNE, is a Professor of Practice in the Nursing Program at Wittenberg University in Springfield, Ohio

Read more less

WHARTON on DYNAMIC COMPETITIVE STRATEGY "A valuable contribution, this insightful book makes it clear that strategy is not a one-time search for a sustainable competitive advantage, but a continuous monitoring of the environment, consumers, and competitors with the object of making the right moves in a dynamically changing competitive landscape." -Philip Kotler S.C. Johnson & Sons Distinguished Professor of International Marketing J. L. Kellogg Graduate School of Management Northwestern University. "An ambitious and welcomed effort at addressing strategy from an interdisciplinary perspective." -Professor Don Lehmann Columbia University Graduate School of Business. "Wharton on Dynamic Competitive Strategy weaves together an unprecedented interdisciplinary analysis of competitive strategies that any global manager should consider indispensable reading...An impressive book." -Jon M. Huntsman, Sr. Chairman and CEO Huntsman Corporation. "Provocative and meaningful . . . Provides an excellent framework for formulating strategy." -Sam Morasca Vice President, Marketing Shell Oil Products Company. "A Rosetta stone for strategy. Read it and keep it by your side!" -Dale Moss Executive Vice President, Sales and Marketing USA British Airways, New York The competitive challenges facing you are more complex and fast-moving than ever. This environment demands dynamic competitive strategies-strategies that anticipate and adjust to competitors' countermoves, shifting customer demands, and changes in the business world. Wharton on Dynamic Competitive Strategy offers new perspectives on competitive strategy from a distinguished group of faculty at Wharton and other leading business schools around the world. This book presents the best insights from decades of research in key areas such as competitive strategy, simulations, game theory, scenario planning, public policy, and market-driven strategy. It represents the most cohesive collection of insights on strategy ever assembled by a leading school of business. Developed for the thinking manager, Wharton on Dynamic Competitive Strategy provides deep insights into the true dynamics of competition. In contrast to popular, quick-fix formulas for strategic success, this book provides perspectives that will help you better understand the underlying dynamics of competitive interactions and make better strategic decisions in a rapidly changing and uncertain world. The insights and approaches presented here are illustrated with real-world examples which demonstrate how these approaches can be applied to your strategic challenges. These chapters will help you better address key strategic issues such as: * Anticipating competitors' responses using game theory, simulations, scenario planning, conjoint analysis, and other tools-and designing the best strategy in light of these expected responses * Planning for multiple rounds of competition in the way that chess players think through multiple moves * Understanding how changes in technology and public policy or moves by competitors can undermine your current advantages or neutralize future advantages * Broadening your range of options for reacting to moves by competitors * Signaling and preempting rivals. This groundbreaking new book will change your view of strategy and give you the tools you need to succeed in a dynamic and intensely challenging world.

Read more less

P-glycoprotein (P-gp), encoded by the multidrug-resistance (MDR)-1 gene is one of the best studied efflux transporters that is linked to multidrug resistance in cancer chemotherapies. P-gp belongs to the ATP-binding cassette (ABC) transporter family of proteins that utilizes energy derived from hydrolysis of ATP to efflux endogenous and exogenous xenobiotics, metabolites and toxins from the intracellular space to the outside, thereby providing a general protective role. P-gp is expressed on the apical plasma membrane of all major drug eliminating organs such as the intestine (enterocytes), liver (bile canaliculi), kidney (proximal tubules), brain (endothelia of blood-brain barrier) and in certain tumor types. In the intestine and BBB, P-gp limits entry of drugs by actively pumping drugs back into the lumen or blood, respectively. In the liver and kidney, P-gp actively effluxes drugs, endogenous substances and metabolites into bile or urine, thereby removing them from the body. Upregulation of P-gp in tumor cells is noted in several cancers and is a hallmark for drug resistance. Additionally, P-gp is also shown to play a role in neurogenesis and maintaining homeostasis in the brain. Alteration of P-gp expression is observed in neurodegenerative diseases, highlighting its importance in maintaining normal brain health. Due to its central role in defining oral pharmacokinetics, systemic clearance, tissue exposure, organ health and chemoresistance, much of the research has been focused on modulating P-gp. Chemical inhibitors, formulation-based and epigenetic approaches are applied to modulate P-gp activity with a goal to improve oral pharmacokinetics, increase tumor and brain penetration, minimize organ toxicity and potentially treat neurodegenerative diseases. Although enormous research on P-gp has been published, a book chapter exclusively and comprehensively covering diverse aspects of P-gp, including the recent developments in the field, is required. With much enthusiasm from the publisher, we have collaborated to bring together wide-ranging topics on P-gp. This book contains 12 chapters covering the structure, function, regulation, distribution and expression of P-gp, its pharmacological importance in health and disease and role in pharmacokinetics and drug-drug interactions. Also included are computational approaches to identify selective inhibitors and tactics to modulate P-gp function using chemical inhibitors (synthesized or isolated from marine sources), formulation strategies or epigenetic approaches. The last chapter describes various methods to quantify P-gp expression levels and function in in vitro, in situ and in vivo settings. It is our sincere hope that this material will serve as an important desk reference for students, researchers and clinical scientists in academia, medical research and the pharmaceutical industry working in various fields such as pharmacology, pharmacy, toxicology, medicinal chemistry, pharmaceutical sciences, pharmacokinetics and computational biology. Finally, we wish to acknowledge the contributions of all the authors who passionately contributed to this book. We also extend our gratitude to the editorial staff and production manager at Nova publishers. Lastly, but most importantly, we thank our families for their continued support during this journey.

Read more less

Daniel Albalate has produced the most comprehensive review of critical issues facing private participation in European motorways to date. The book's scope is breathtaking, offering a concise history of the development of European roads, and the main reasons for the failure of many European motorway public-private partnerships while reviewing the design of road public-private partnerships. Readers will come away with a fresh understanding of interactions between public policy and private participation in road construction, financing, operation and maintenance'- Rick Geddes, Associate professor in the Department of Policy Analysis and Management at Cornell University'Daniel Albalate provides the most comprehensive and updated analysis on privatization and nationalization of motorways in Europe. Albalate's thorough review of the trends in the ownership, management and financing of European motorways is a must-read for anybody interested in what are the factors that favor or undermine private participation in this type of infrastructure, which is a subject of increasing interest in the public policies in Europe, and throughout the world. This book provides very useful insights for scholars, and also relevant implications for policy makers.'- Germà Bel, University of Barcelona, SpainThis distinctive and timely book examines the current state and trends in the ownership, management and financing of European high capacity roads. Offering an analysis of three pioneer countries in road privatization, Spain, France and Italy, from their origins to their recent developments, it evaluates how the design of privatization policies may lead to their success or failure.Describing the trend in favoring public-private collaboration and road charging, Professor Daniel Albalate presents the theoretical framework of road privatization and its relevant design issues. Exhaustively studying the national experiences in historical perspective, he aims at providing lessons on the good, the bad and the ugly of road privatisation. As a result, this excellent study shows the increasing role of private financing and ownership in Europe, a trend mainly explained by fiscal motivations and the thrust of the European Commission.Presenting an evaluation of the critical elements of the contractual and regulatory design of the public-private collaboration that determines the likelihood of success and failure, this unique book will be of special interest to academics, graduate students and policy makers interested in the public provision and financing of road infrastructure, and public finance more generally.Contents: Preface Introduction Part I: A Favourable Trend to Privatisation 1. European Roads: Origins and Models of the Past 2. Motorway Privatisation in Europe Part II: Economics of Road Privatisation and the Design of PPPs 3. Privatisation and Regulation of Motorways: The Background 4. The Design of Public-Private Collaboration 5. Demand Risk Mitigation Mechanisms 6. When Privatisation Fails: Bailouts, Renegotiations and Nationalisations Part III: Selected Experiences in Historical Perspective 7. Spain 8. Italy 9. France Part IV: Evaluation PPPs: What We Know About Motorway Privatization 10. An Evaluation of the Private Participation in the Motorway Industry 11. Conclusions References Index

Read more less

WHARTON on DYNAMIC COMPETITIVE STRATEGY "A valuable contribution, this insightful book makes it clear that strategy is not a one-time search for a sustainable competitive advantage, but a continuous monitoring of the environment, consumers, and competitors with the object of making the right moves in a dynamically changing competitive landscape." -Philip Kotler S.C. Johnson & Sons Distinguished Professor of International Marketing J. L. Kellogg Graduate School of Management Northwestern University. "An ambitious and welcomed effort at addressing strategy from an interdisciplinary perspective." -Professor Don Lehmann Columbia University Graduate School of Business. "Wharton on Dynamic Competitive Strategy weaves together an unprecedented interdisciplinary analysis of competitive strategies that any global manager should consider indispensable reading...An impressive book." -Jon M. Huntsman, Sr. Chairman and CEO Huntsman Corporation. "Provocative and meaningful . . . Provides an excellent framework for formulating strategy." -Sam Morasca Vice President, Marketing Shell Oil Products Company. "A Rosetta stone for strategy. Read it and keep it by your side!" -Dale Moss Executive Vice President, Sales and Marketing USA British Airways, New York The competitive challenges facing you are more complex and fast-moving than ever. This environment demands dynamic competitive strategies-strategies that anticipate and adjust to competitors' countermoves, shifting customer demands, and changes in the business world. Wharton on Dynamic Competitive Strategy offers new perspectives on competitive strategy from a distinguished group of faculty at Wharton and other leading business schools around the world. This book presents the best insights from decades of research in key areas such as competitive strategy, simulations, game theory, scenario planning, public policy, and market-driven strategy. It represents the most cohesive collection of insights on strategy ever assembled by a leading school of business. Developed for the thinking manager, Wharton on Dynamic Competitive Strategy provides deep insights into the true dynamics of competition. In contrast to popular, quick-fix formulas for strategic success, this book provides perspectives that will help you better understand the underlying dynamics of competitive interactions and make better strategic decisions in a rapidly changing and uncertain world. The insights and approaches presented here are illustrated with real-world examples which demonstrate how these approaches can be applied to your strategic challenges. These chapters will help you better address key strategic issues such as: * Anticipating competitors' responses using game theory, simulations, scenario planning, conjoint analysis, and other tools-and designing the best strategy in light of these expected responses * Planning for multiple rounds of competition in the way that chess players think through multiple moves * Understanding how changes in technology and public policy or moves by competitors can undermine your current advantages or neutralize future advantages * Broadening your range of options for reacting to moves by competitors * Signaling and preempting rivals. This groundbreaking new book will change your view of strategy and give you the tools you need to succeed in a dynamic and intensely challenging world.

Read more less

Circuit designers, packaging engineers, printed board fabricators, and procurement personnel will find this book's microelectronic package design-for-reliability guidelines and approaches essential for achieving their life-cycle, cost-effectiveness, and on-time delivery goals. Its uniquely organized, time-phased approach to design, development, qualification, manufacture, and in-service management shows you step-by-step how to: * Define realistic system requirements in terms of mission profile, operating life, performance expectations, size, weight, and cost * Define the system usage environment so that all operating, shipping, and storage conditions, including electrical, thermal, radiation, and mechanical loads, are assessed using realistic data * Identify potential failure modes, sites, mechanisms, and architecture-stress interactions--PLUS appropriate measures you can take to reduce, eliminate, or accommodate expected failures * Characterize materials and processes by the key controllable factors, such as types and levels of defects, variations in material properties and dimensions, and the manufacturing and assembly processes involved * Use experiment, step-stress, and accelerated methods to ensure optimum design before production begins Detailed design guidelines for substrate...wire and wire, tape automated, and flip-chip bonding...element attachment and case, lead, lead and lid seals--incorporating dimensional and geometric configurations of package elements, manufacturing and assembly conditions, materials selection, and loading conditions--round out this guide's comprehensive coverage. Detailed guidelines for substrate...wire and wire, tape automated, and flip-chip bonding...element attachment and case, lead, lead and lid seals--incorporating dimensional and geometric configurations of package elements, manufacturing and assembly conditions, materials selection, and loading conditions--round out this guide's comprehensive coverage. of related interest... PHYSICAL ARCHITECTURE OF VLSI SYSTEMS --Allan D. Kraus, Robert Hannemann and Michael Pecht For the professional engineer involved in the design and manufacture of products containing electronic components, here is a comprehensive handbook to the theory and methods surrounding the assembly of microelectronic and electronic components. The book focuses on computers and consumer electronic products with internal subsystems that reflect mechanical design constraints, cost limitations, and aesthetic and ergonomic concerns. Taking a total system approach to packaging, the book systematically examines: basic chip and computer architecture; design and layout; interassembly and interconnections; cooling scheme; materials selection, including ceramics, glasses, and metals; stress, vibration, and acoustics; and manufacturing and assembly technology. 1994 (0-471-53299-1) pp. SOLDERING PROCESSES AND EQUIPMENT --Michael G. Pecht This comprehensive, fundamentals first handbook outlines the soldering methods and techniques used in the manufacture of microelectronic chips and electronic circuit boards. In a clear, easy-to-access format, the book discusses: soldering processes and classification; the material dynamics of heat soldering when assembling differing materials; wave and reflow soldering; controlling contamination during manufacturing cleanings; techniques for assuring reliability and quality control during manufacturing; rework, repair, and manual assembly; the modern assembly / repair station; and more. The book also provides clear guidelines on assembly techniques as well as an appendix of various solder equipment manufacturers. 1993 (0-471-59167-X) 312 pp.

Read more less

Over the past decade there has been a resurgence of interest in growing fruit and vegetables in the garden and on the allotment. Part of the driving force behind this is an increased awareness of the health benefits that can be derived from fruit and vegetables in the diet. The 'five helpings a day' dictum reflects the correlation between a regular consumption of fruit and vegetables and a reduced incidence of, for example, cardiovascular disease and some cancers. Growing your own vegetables provides the opportunity to harvest them at their peak, to minimize the time for post-harvest deterioration prior to consumption and to reduce their 'food miles'. It also provides an opportunity to grow interesting and less common cultivars. The combination of economic advantages and recreational factors add to the pleasure of growing fruit and vegetables. This book covers the natural products that have been identified in common 'home-grown' fruit and vegetables and which contribute to their organoleptic and beneficial properties. Over the last fifty years the immense advances in separation methods and spectroscopic techniques for structure elucidation have led to the identification of a wide range of natural products in fruit and vegetables. Not only have many of their beneficial properties been recognized but also their ecological roles in the development of plants have been identified. The functional role of many of these natural products is to mediate the balance between an organism and its environment in terms of microbial, herbivore or plant to plant interactions. The book is aimed at readers with a chemical background who wish to know a little more about the natural products that they are eating, their beneficial effects, and the roles that these compounds have in nature. Developments in the understanding of the ecological and beneficial chemistry of fruit and vegetables have made the exploration of their chemical diversity a fascinating and expanding area of natural product chemistry and readers will obtain some 'taste' for this chemistry from the book. It develops in more detail the relevant sections from the earlier RSC book 'Chemistry in the Garden'. The book begins with an outline of the major groups of compound that are found in fruit and vegetables. This is followed by a description of aspects of environmental chemistry that contribute to the successful cultivation of these crops. Subsequent chapters deal with individual plants which are grouped in terms of the part of the plant, roots, bulbs and stems, leaves, seeds, that are used for food. The final chapters deal with fruit and herbs. The epilogue considers some general aspects of ecological chemistry and climatic stress which may, in the future, affect the growth of fruit and vegetables in the garden particularly in the context of potential climate changes. The book concludes with a section on further reading, a glossary of terms used in plant chemistry and a list of the common fruit and vegetables grouped in their plant families.

Read more less

From hormones to stretch marks, labor pains to diaper changes, motherhood is an adventure like none other. The rapid changes in your body, your lifestyle, and your very identity call for a certain mental and emotional agility. Mindfulness can help you meet the challenge and approach every experience with your new baby with open eyes and an open heart. Based on research conducted at California Pacific Medical Center, and with a foreword by beloved meditation teacher Sylvia Boorstein, Mindful Motherhood: Practical Tools for Staying Sane During Pregnancy and Your Child's First Year (New Harbinger/Noetic Books, May 2009, $16.95) by psychologist and mom Cassandra Vieten, has been acclaimed by women's health experts, mindfulness teachers, and psychologists alike.Mindful Motherhood provides pregnant women and new moms with a brief, low-cost, easy to implement set of tools to deal with stress, difficult moments, depressed or anxious moods, and negative thought patterns during pregnancy and early motherhood. Based on the principles of mindfulness, this book also provides information, exercises, and ideas to enhance the positive emotions that are part of the experience of motherhood and improve the quality of mother-infant interactions, bringing more attention and awareness to the deep joy and satisfaction that motherhood can bring.Mindful Motherhood provides pregnant women and early moms with:1) accessible information based on science and sound clinical theory,2) practical tools for practicing mindfulness in everyday life,3) stories and examples to inspire interest and clarify points, and4) experiential exercises that will help readers integrate the informationand experiences they have.Mindful Motherhood also offers current insights into the positive psychology of motherhood and mother-infant attachment, translating science and theory into jargon-free language and immediately applicable tools. This book is aimed specifically toward pregnant women and mothers with infants, who would like to deal more effectively with stress and mood during pregnancy and postpartum, who are interested in being the best parent they can be, and who want to cultivate a deeper connection to themselves and their children.The goal is to help women become the kind of present, authentic, connected, emotionally competent, psychologically-balanced, and loving mothers they want to be not to mention enjoying the extraordinary experience of motherhood to its fullest extent.Why it is ImportantA large body of evidence in both animal and human studies indicates that stress and mood disturbance experienced during pregnancy increases the risk for preterm birth, low birth weight, and other pregnancy-related complications, and may adversely affect the developing fetus. Postnatal mood disturbance can interfere with attachment, healthy parenting behaviors, and child development. While a wealth of evidence supports all these facts, surprisingly little information is available to women and clinicians for reducing stress and improving mood in pregnancy and postpartum.Mindful Motherhood is the only book oriented toward teaching research-based mindfulness principles to reduce stress and improve mood in pregnant women and new moms. It is an easy but informative read that gives new moms the psychology, science and health facts behind how mindfulness can enhance mother-infant attachment, and be used in childbirth.

Read more less

How can new understandings about cancer cell interactions help doctors better control, and eventually cure, cancer?Cancer is a formidable enemy. In fact, people born in America since 1960 face a one in two chance of being diagnosed with cancer in their lifetimes. However, there's growing evidence that fewer cancers will be death sentences for patients. New approaches and understandings are transforming the medical world, increasing success rates for remissions, disease management, and cures. Dr. Ashani Weeraratna is at the forefront of this new level of care. In Is Cancer Inevitable?, Weeraratna—a pioneering melanoma researcher whose work explores the role aging plays in cancer cells' spread and drug resistance—gives readers an inside look at several of the latest cancer advances. Detailing the actions that are reducing the disease's impact and exploring what the future may hold, she explains how the molecular mechanisms involved in metastasis and the cells' microenvironments influence cancer's development and progression. Over the years, she writes, our understanding of how cancer cells move throughout the body, change as they plant themselves in the body's microenvironments, and even communicate with one another have led to major insights about how cancer works. With compelling detail, she takes us inside her lab, revealing how new insights are leading to major breakthroughs, even among patients with Stage IV cancer. She also explains how age-related changes in the microenvironment contribute to multiple aspects of melanoma formation and development. Such scholarship, she argues, is moving us toward a day when more patients will be declared cancer-free. An inspiring and deeply personal book, Is Cancer Inevitable? offers readers newfound hope.Features• Explores key insights and studies developed in recent years that have greatly influenced the world of cancer research, including how aging microenvironments within our bodies encourage metastasis and therapy resistance• Guides readers through Dr. Ashani Weeraratna's personal story of coming to the United States from Lesotho at the age of 17 and rising to become one of the pioneers in her field• Brings readers inside Weeraratna's lab, describing both the processes and the missions of her work • Raises awareness about how cancer works within the body and what any patient or family encountering the disease needs to understand—while also offering them hope based on new and forthcoming diagnostic and treatment methods• Outlines why we will never control—let alone cure—cancer if we don't find a common purpose and come together in collaboration, inviting the greatest minds from around the world to participate in finding and implementing solutionsJohns Hopkins WavelengthsIn classrooms, field stations, and laboratories in Baltimore and around the world, the Bloomberg Distinguished Professors of Johns Hopkins University are opening the boundaries of our understanding of many of the world's most complex challenges. The Johns Hopkins Wavelengths book series brings readers inside their stories, illustrating how their pioneering discoveries benefit people in their neighborhoods and across the globe in artificial intelligence, cancer research, food systems' environmental impacts, health equity, science diplomacy, and other critical arenas of study. Through these compelling narratives, their insights will spark conversations from dorm rooms to dining rooms to boardrooms.

Read more less

Table of Contents Preface and Acknowledgments Introductory note Abbreviations A. OPENING LECTURE - Liv Helga DOMMASNES , Women in archaeology in Norway : twenty years of gendered archaeological practice and some thoughts about changes to come B. PLENARY SESSION ' A TRIBUTE TO PAUL REHAK: PAST AND PRESENT GENDER ISSUES, A STATE OF ART - Paul REHAK (ed. John YOUNGER), Some unpublished studies by Paul Rehak on gender in Aegean art - Alexandra ALEXANDRI, Envisioning gender in Aegean prehistory - Dimitra KOKKINIDOU and Marianna NIKOLAIDOU, Feminism and Greek archaeology: an encounter long over-due C. WORLDS OF WOMEN, MEN AND BEYOND: GENDER IDENTITIES, ROLES, INTERACTIONS, SYMBOLISMS Cyprus - Diane BOLGER, Beyond male/female: recent approaches to gender in Cypriot prehistory - Giorgos VAVOURANAKIS, A 'speared Aphrodite' from Bronze Age Audemou, Cyprus Jordan - Julia MULLER-CLEMM, Cemetery A of Tell el-Mazar, Jordan. A gender-critical relecture Spain - Paloma GONZALEZ-MARCEN and Sandra MONTON-SUBIAS, Time, women, identity and maintenance activities. Death and life in the Argaric communities of southeast Iberia - Margarita SANCHEZ-ROMERO, Women in Bronze Age southeast Iberian peninsula : daily life, relationships, identities Aegean and the Balkans - Christina MARANGOU, Gendered/sexed and sexless beings in prehistory: readings of the invisible gender Aegean - Louise A. HITCHCOCK, Knossos is burning: gender bending the Minoan genius - Penelope J.P. McGEORGE, Gender meta-analysis of Late Bronze Age skeletal remains: the case of Tomb 2 in the Pylona cemetery on Rhodes - Barbara A. OLSEN, Was there unity in Mycenaean gender practices? The women of Pylos and Knossos in the Linear B tablets - Kim S. SHELTON, Who wears the horns? Gender choices in Mycenaean terracotta figurines - Alexander UCHITEL, The Minoan Linear A sign for 'woman': a tentative identification - Judith WEINGARTEN, The Zakro master and questions of gender - Marika ZEIMBEKI, Gender, kinship and material culture in Aegean Bronze Age ritual D. FORMATION OF PAST GENDER: COMING OF AGE, CHILDHOOD, WOMANHOOD, MOTHERHOOD - Francoise AUDOUZE and Frederic JANNY, Can we hope to identify children's activities in Upper Palaeolithic settlements? - Anne P. CHAPIN, Constructions of male youth and gender in Aegean art: the evidence from Late Bronze Age Crete and Thera - Katerina KOPAKA, Mothers in Aegean stratigraphies? The dawn of ever-continuing engendered life cycles - Maia POMADERE, OA' sont les meres ? Representations et realites de la maternite dans le monde egeen protohistorique - John G. YOUNGER, 'We are woman': girl, maid, matron in Aegean art E. READING AEGEAN GENDER: THROUGH WOMEN'S AND MEN'S EYES - Isabelle BRADFER-BURDET, Phedre ou la Goulue : l'antiquite travestie. Les femmes de l'Age du Bronze mises a nu par les archeologues du XXeme siecle - Gerald CADOGAN, Gender metaphors of social stratigraphy in pre-linear B Crete , or Is 'Minoan gynaecocracy' (still) credible? - Lucy GOODISON, Gender, body and the Minoans: contemporary and prehistoric perceptions - Christine MORRIS, The iconography of the bared breast in Aegean Bronze Age art F. ENGENDERING AEGEAN FIELDWORK: THE CONTRIBUTION OF WOMEN ARCHAEOLOGISTS - Susan Heuck ALLEN, Excavating women: female pairings in early Aegean archaeology (1871-1918) - Anna Lucia D'AGATA, Women archaeologists and non-palatial Greece : a case-study from Crete'of the hundred cities' - Metaxia TSIPOPOULOU, Harriet Boyd's 'granddaughters': women directors of excavations and surveys in Crete at the end of the 20th and the beginning of the 21st century

Read more less

What does it mean to love with technology? Does data improve our emotional interactions? The collection approaches the query with critical essays and works of new media art to look into the construction of love and its practices in the time of digitally mediated relationships. With expertise coming from recognized researchers, critics and artists in the field of media and cultural studies, it analyses relationship trends and affect cultures that have emerged from technological acceleration. Data Dating: Love, Technology and Desire is a comprehensive study of love and intimacy under digitalism that reflects on the structure of feeling(s) and libido environments in the high-tech and media-bound landscapes of contemporary technocracies. Organized around ten chapters and ten works of new media art, the collection offers an extensive critical analysis of technologized romance (and other emotional relations), as well as provides an insight into the codification, execution, deployment, and evolution of the patterns of togetherness in the so-called Tamagotchi era. The chapters engage in the problems of new material planes that have emerged from the abstraction of networked communication and dispersion of traditional notions of physicality. They close-read the templates of contemporary fantasy, fetish and eroticism, as shaped by platform capitalism, datafication, and new commodity cultures, in which self-promotion for bonding relies on the new possibilities that are coming in with new media self-mediation formats. Central to the analysis is the carbon-silicon dynamics of love’s contemporary DNA and libidinal techne – practiced in the environment where screens, interfaces, algorithms, data protocols and non-organic objects of affection and affect delineate, organize and program the trajectories of encounter, limerence and erotic pleasure. All the chapters are authored by recognized researchers in the field of love, emotion, media, technology and cultural studies, and they critically explore various aspects of love/intimacy under technocracy, approaching them with expertise the goes beyond the typical high-modernist and post-structural reading of the media-ridden life practices and environments. More importantly, the collection includes landmark works of new media art coming from prominent new media artist gathered around 'Data Dating' – new media art exhibition, curated by Valentina Peri (co-editor of the collection) and presented in Paris, Tel Aviv and London. As such, the collection proffers a unique and original critical approach – one that combines artistic practice and cultural criticism – to comment upon the transformation of human relationships and emotional standards under technological development with reference to the social change and cultural condition. The collection of essays, each accompanied by a work of media art, that provides a comprehensive insight into the construction of love and its practices in the time of digitally mediated relationships. Primary readership will be among educators, researcher and students in disciplines including cultural studies, media and communications, philosophy, sociology, psychology and gender, LGBTQ+ and sexual studies. It will be an extremely valuable resource for those in these fields. It will be of interest to other groups including art curators, online platform designers, social media content managers and designers and data specialists.

Read more less

We are extremely happy to introduce our new book, Recent Advances in Computer Aided Drug Designing. While interacting with many researchers in the field of biotechnology and allied sciences, we felt that there was need for a book that could easily bridge the gap between in silico methods applied in structural bioinformatics for drug designing and wet lab workers. Today, when computational skills in biology and biomedical research are in high demand, this book presents updated content for methods and tools applicable in modern computer-aided drug designing. Researchers are pouring knowledge into databases that are publicly available and laboratories across the globe are accessing this information for analysis and further investigation. There is a battery of data scientists involved in development and maintenance of online databases. Alongside them, there is another class of programmers and scientists involved in development of software tools for analysis of this data. Modern tools based on machine learning are available to provide accuracy and efficiency with speedy analysis of biological and biomedical data. In many cases, analysis of readily available biological data helps to decide future directions for laboratory work. Indications obtained from such analytics save time and resources which could be very crucial in general. Publicly available protein three-dimensional structure and drug databank libraries have facilitated the drug discovery process. Millions of drugs can be screened in a few hours by using virtual screening tools. Molecular viewing tools can be used to visualize macromolecules and their interactions with drugs. Findings from such studies are being used to validate results directly in laboratories. Efforts have been made to cover all areas relevant for computer-aided drug designing to allow this book to serve as a standard reference book and meet the requirements of graduate students and researchers working in drug design and structural bioinformatics. Some chapters are dedicated to basic concepts in computer-aided drug discovery while other chapters present applications of the available tools in the field. Contents from exemplary method-based chapters are easy to follow and will help new researchers in applying contemporary tools for their studies. The book will also stimulate programmers and data scientists interested in developing tools for structural bioinformatics applications to develop new and improved versions of software. Chapters presenting the basic concepts of methods involved in drug design will help new learners in the field to meet the challenges of designing novel therapeutics by using computational tools. Cross-disciplinary research is in trend nowadays and such investigations involving experts of their respective fields are highly promising and fruitful. Drug discovery requires experts from health sciences and medical sciences, molecular biologists, bioinformaticians, biotechnologists, biochemists, statisticians, biophysicists and clinicians. For a complete piece of translated product such as a drug, inputs from specialist researchers are needed. Modern rational drug discovery approaches are truly inter-disciplinary fields which require a systems biology approach for successful ventures. This book covers all steps of drug design, from drug target identification to intermediate steps to successful clinical trials, making it truly essential for modern researchers in the drug discovery and structural bioinformatics fields.

Read more less

The Way Forward for Entrepreneurship Around the World We are in the midst of a startup revolution. The growth and proliferation of innovation-driven startup activity is profound, unprecedented, and global in scope. Today, it is understood that communities of support and knowledge-sharing go along with other resources. The importance of collaboration and a long-term commitment has gained wider acceptance. These principles are adopted in many startup communities throughout the world. And yet, much more work is needed. Startup activity is highly concentrated in large cities. Governments and other actors such as large corporations and universities are not collaborating with each other nor with entrepreneurs as well as they could. Too often, these actors try to control activity or impose their view from the top-down, rather than supporting an environment that is led from the bottom-up. We continue to see a disconnect between an entrepreneurial mindset and that of many actors who wish to engage with and support entrepreneurship. There are structural reasons for this, but we can overcome many of these obstacles with appropriate focus and sustained practice. No one tells this story better than Brad Feld and Ian Hathaway. The Startup Community Way: Evolving an Entrepreneurial Ecosystem explores what makes startup communities thrive and how to improve collaboration in these rapidly evolving, complex environments. The Startup Community Way is an explanatory guide for startup communities. Rooted in the theory of complex systems, this book establishes the systemic properties of entrepreneurial ecosystems and explains why their complex nature leads people to make predictable mistakes. As complex systems, value creation occurs in startup communities primarily through the interaction of the "parts" - the people, organizations, resources, and conditions involved - not the parts themselves. This continual process of bottom-up interactions unfolds naturally, producing value in novel and unexpected ways. Through these complex, emergent processes, the whole becomes greater and substantially different than what the parts alone could produce. Because of this, participants must take a fundamentally different approach than is common in much of our civic and professional lives. Participants must take a whole-system view, rather than simply trying to optimize their individual part. They must prioritize experimentation and learning over planning and execution. Complex systems are uncertain and unpredictable. They cannot be controlled, only guided and influenced. Each startup community is unique. Replication is enticing but impossible. The race to become "The Next Silicon Valley" is futile - even Silicon Valley couldn't recreate itself. This book: Offers practical advice for entrepreneurs, community builders, government officials, and other stakeholders who want to harness the power of entrepreneurship in their city Describes the core components of startup communities and entrepreneurial ecosystems, as well as an explanation of the differences between these two related, but distinct concepts Advances a new framework for effective startup community building based on the theory of complex systems and insights from systems thinking Includes contributions from leading entrepreneurial voices Is a must-have resource for entrepreneurs, venture capitalists, executives, business and community leaders, economic development authorities, policymakers, university officials, and anyone wishing to understand how startup communities work anywhere in the world

Read more less

This book presents a compelling attack on the patent system. Thoughtfully analyzing the existing empirical literature and providing her own painstaking study of business method patents, Hazel Moir explains how it is that. . . patents have spread geographically and technologically, with increasingly broad rights becoming ever-easier to obtain. Bravely and persuasively, she recommends policymakers tackle one of the most vexing issues in patent law: the quantum of new knowledge that ought to be required to make an invention worthy of protection.'- Rochelle Dreyfuss, New York University School of Law, US'Hazel Moir's book deserves to become a classic. Between its covers one will find writing of great clarity and data that reveal the real world costs of the patent system. After reading Moir's analysis, one wonders what the actual social benefits of the patent system might be. This is evidence-based analysis at its best.'- Peter Drahos, Australian National University and Queen Mary, University of London, UK'Just how inventive are inventions? More to the point, just how inventive are the inventions covered by patents? Not very, according to Hazel Moir, and there is no reason to doubt her conclusions. She has spent years in painstakingly analysis of dozens of business method patents in Australia and elsewhere. She finds. . . [t]hey are no more than strategic devices intended to annoy and disrupt commercial competition and confuse the market. . . Hazel Moir is a patent expert beholden to no patent theory and no patent interests. In consequence, her research is fresh and inspired. Her conclusion - that patents describe and protect obvious combinations of old ideas and trivial variations - may not be confined to business methods. It is a conclusion that demands the consideration of policymakers.'- Stuart Macdonald, Aalto University, Helsinki, FinlandThis empirical study uses a scientifically selected sample of patents to assess patent quality. The careful evaluation of the assumptions in alternative economic theories about the generation and diffusion of new knowledge demonstrates that the height of the inventive step is critical to effective and efficient patent policy.The book provides a practical introduction to the policy rules affecting the grant of patents, particularly the rules making the inventive step so low. It also offers insights into interactions between examiners and applicants during the patent application process. Finally, the book compares how the rules about inventiveness operate in the USPTO, the EPO and the Australian Patent Office, gives new insights into business method patenting and offers suggestions for raising the height of the inventive step.Patent Policy and Innovation will appeal to academics researching in the patent field, economists, innovation and industry policy advisors, patent policy makers, NGO policy advisors and patent practitioners.Contents: Preface 1. Introduction 2. The Economics of Patent Policy: Assumptions, Paradoxes and Evidence 3. Who Determines Patent Policy: Judges, Lobbyists or Legislatures? 4. In the National Interest: Defining Patentable Inventions 5. Finding and Avoiding Existing Knowledge 6. Combining Known Elements 7. The Quantum of Inventiveness: Other Approaches and Rules 8. Rebalancing the Patent System Appendix. Original Claims: Selected Patents References Index

Read more less

conduct disorder and under-achievement The young people who are the subject of this book are responsiblefor a disproportionate amount of difficulty for society. They arethe chronic rule-breakers and bullies. They may threaten,intimidate, manipulate, steal, and use violence to get what theywant. Many are drug abusers and drug dealers. Most have problems with self-control and self-discipline. Nearlyall of them are academic underachievers. Unfortunately, they arealso incredibly resistant to psychological intervention. Exhibitinga range of behaviors grouped under the DSM rubric "ConductDisorder," these children and adolescents are legion and theirnumbers continue to grow at an alarming rate. In Conduct Disorder and Underachievement, a leading authority on CDunderachievers explores the causes, assessment, treatment, andprevention of disruptive behavioral problems in underachievingchildren and adolescents. He summarizes many of the assessmenttools developed for CD underachievers and provides a unique,comprehensive risk-factor model which can be used to help identifydisorder problems before they occur. And, perhaps most importantly,he describes a dynamic cognitive/developmental treatment modelwhich has proven to be extraordinarily successful with certaintypes of CD underachievers. Conduct Disorder and Underachievement offers new hope for findingpsychological solutions to one of today's most pressing socialproblems. Much has been unearthed in recent years about the origins anddevelopment of conduct disorder (CD) in children and adolescents.Yet there is still considerable disagreement about the roleacademic underachievement plays in CD. Is underachievement acontributing factor to or a result of CD? While the jury is stillout on this issue, one thing is certain: eventually, therelationship between them becomes a dialectical one--bad grades andantisocial behavior usually go hand in hand. Can this seeminglyfacile observation provide the basis for interventions with certaintypes of conduct disorders? In Conduct Disorder andUnderachieve-ment, a leading authority on underachievement answersthat question with a resounding "Yes" and demonstrates how. Dr. Mandel begins with a thorough review of the latest researchfindings on the etiology, assessment, and treatment of conductdisorder in children and adolescents. From there, the focus narrowsto issues of CD underachievement. While most forms of conductdisorder and underachievement are discussed, the clinical emphasisis on less severely disturbed children for whom underachievement isstill manageable but, if left unchecked, can lead to more severeconduct problems. Through the window of two case histories completewith test results and diagnostic interviews, Dr. Mandel exploresthe full range of assessment issues, critically examinespredominant treatment strategies, and provides helpful preventionguidelines. In the prescriptive portion of the book, the author delineates acognitively oriented approach to treating CD underachievers. Heespouses a treatment strategy based on the assumption that, fromone case to the next, underachievement may either contribute to orresult from conduct disorder. The most constructive approach,therefore, is to reconstruct the unfolding of individual scenariosand then determine what can be done to mend fractured developmentalpathways. Through a series of therapy excerpts which take thereader inside a treatment session, Dr. Mandel brings to vivid lifethe issues that must be dealt with, the struggles that must beovercome, and the complex interactions that develop between childand therapist during therapeutic intervention. Combining a comprehensive review of the latest findings with adynamic new approach to intervention, Conduct Disorder andUnderachievement is a valuable resource for mental healthprofessionals, guidance counselors, and educators who deal withthis increasingly common problem.

Read more less

Beset by the angry remnants of the Department of the Interior, challenged at every turn by opportunists on their new homeworld of Surebleak, and somewhat low on funds, Clan Korval desperately needs to reestablish its position as one of the top trading clans in known space. To this end, Master Trader Shan yos'Galan, aboard Korval's premier trade ship, Dutiful Passage, is on a mission to establish new business associations and to build a strong primary route that links well with existing Loops and secondary routes. But reestablishing trade and preserving the lives of the remaining members of the clan aren't all of Korval's problems. Matters come to a head as Dutiful Passage, accustomed to being welcomed and feted at those ports on its call-list, finds itself denied docking, and blacklisted, while agents of the DOI mount armed attacks on others of Korval's traders, under the very eyes of port security systems. Traveling with Dutiful Passage on this unsettling journey is Padi yos'Galan, the master trader's heir and his apprentice. Padi is eager to make up for time lost due to Korval's unpleasantness with the Department of the Interior. She is also keeping a secret so intense that her coming of age, and perhaps her very life, is threatened by it. About Alliance of Equals: " . . . continues to delight with genteel interactions between mild-spoken characters who are capable of great passions and swift actions, and its immense scope encompasses a well-realized and comfortable universe."—Publishers Weekly About series prequel Dragon in Exile: “[S]prawling and satisfying. . . . Space opera mixes with social engineering, influenced by Regency-era manners and delicate notions of honor. . . . [I]t’s like spending time with old friends . . .”—Publishers Weekly About Necessity's Child: “Compelling and wondrous, as sharp and graceful as Damascus steel, Necessity's Child is a terrific addition to Lee & Miller's addictive series.”—#1 New York Times best seller, Patricia Briggs About the Liaden Universe® series: “Every now and then you come across an author, or in this case, a pair, who write exactly what you want to read, the characters and personalities that make you enjoy meeting them. . . . I rarely rave on and on about stories, but I am devoted to Lee and Miller novels and stories.”—Anne McCaffrey “These authors consistently deliver stories with a rich, textured setting, intricate plotting, and vivid, interesting characters from fully-realized cultures, both human and alien, and each book gets better.”—Elizabeth Moon “[D]elightful stories of adventure and romance set in a far future. . .space opera milieu. It’s all a rather heady mix of Gordon R. Dickson, the Forsythe Saga, and Victoria Holt, with Lee and Miller’s own unique touches making it all sparkle and sizzle. Anyone whose taste runs toward SF in the true romantic tradition can’t help but like the Liaden Universe.”—Analog “[T]he many fans of the Liaden universe will welcome the latest…continuing young pilot Theo Waitley’s adventures.”—Booklist on Saltation “[A]ficionados of intelligent space opera will be thoroughly entertained. . .[T]he authors' craftsmanship is top-notch.”—Publishers Weekly on Lee and Miller’s popular Liaden Universe® thriller, I Dare

Read more less

Global Governance of Labour Rights provides an outstanding collection of essays examining how international trade relations, trade agreements and non-state actors influence labour rights governance. This well-crafted, coherent, and thoughtful volume will make important contributions to the ongoing debates on the regulation and enforcement of labour rights.'- Aseem Prakash, University of Washington, Seattle, US'The Editors have managed to make, through this volume, a major contribution to the on-going discussion regarding the 'internationalization' of labour rights. Their single most important achievement is that they have produced a coherent 'whole' out of many heterogeneous parts. Both the intra-EU, as well as the international dimension, are skillfully debated in a volume that does not simply view the former as a hothouse for the latter, but discusses the interactions of the two orders in the most systematic way.'- Petros C. Mavroidis, Columbia Law School, New York City, US'This excellent collection of essays provides fresh transnational and critical perspectives on the often ignored topic of labour rights. Ugly reports of collapsed factories and buried workers, of slave-like conditions among migrants and children, continue to horrify readers and viewers worldwide. What can be done? This book contains some long-awaited answers.'- Thomas G. Weiss, The City University of New York's Graduate Center, US'The bulk of the world's governments and a growing number of firms now say they respect labour rights. Yet scholars, activists and policymakers have little understanding of the effectiveness of ILO conventions and government initiatives. In this important and well-written book, we get answers to many of the most pressing questions about how governments and private sector actors can advance labour rights and conditions. Kudos to Marx, Wouters, Rayp and Beke for a must-read book.'- Susan Ariel Aaronson, Research Professor of International Affairs and Director eBay policy scholars, Elliot School, GWUStories and images of collapsed factories, burned down sweatshops, imprisoned migrant workers, child workers and many other violations of internationally recognized labour rights continue to spread across the globe. This highly topical book examines the different instruments which are intended to protect labour rights on a transnational scale, and asks whether they make a difference.With perspectives from law, management, sociology, political science and political economy, the topics discussed include the protection of international labour rights in a globalizing economy, the EU's social dimension in its external trade relations, Asian and US perspectives on labour rights in international trade agreements, the role of (trade) unions in global labour governance and the transformative capacity of private labour governance regimes.Academics and advanced students from different disciplines will benefit from the up-to-date empirical material in this study. Policymakers, NGOs and Unions will find the discussions of the instruments used to protect labour rights of great value to their work.Contributors: L. Beke, R.C. Brown, R. Cörvers, Y. Dahan, J. Donaghey, P. Glasbergen, F. Hendrickx, D. Klink, S. Koch-Baumgarten, M. Kryst, H. Lerner, A. Marx, F. Milman-Sivan, A.-G. 'Tobi' Oshodi, P. Pecinovsky, C. Pekdemir, G. Rayp, J. Reinecke, J. Soares, W. Van Acker, L. Van den Putte, P. van der Heijden, S. Velluti, J. Wouters, R. Zandvliet

Read more less

What does it mean to love with technology? Does data improve our emotional interactions? The collection approaches the query with critical essays and works of new media art to look into the construction of love and its practices in the time of digitally mediated relationships. With expertise coming from recognized researchers, critics and artists in the field of media and cultural studies, it analyses relationship trends and affect cultures that have emerged from technological acceleration. Data Dating: Love, Technology and Desire is a comprehensive study of love and intimacy under digitalism that reflects on the structure of feeling(s) and libido environments in the high-tech and media-bound landscapes of contemporary technocracies. Organized around ten chapters and ten works of new media art, the collection offers an extensive critical analysis of technologized romance (and other emotional relations), as well as provides an insight into the codification, execution, deployment, and evolution of the patterns of togetherness in the so-called Tamagotchi era. The chapters engage in the problems of new material planes that have emerged from the abstraction of networked communication and dispersion of traditional notions of physicality. They close-read the templates of contemporary fantasy, fetish and eroticism, as shaped by platform capitalism, datafication, and new commodity cultures, in which self-promotion for bonding relies on the new possibilities that are coming in with new media self-mediation formats. Central to the analysis is the carbon-silicon dynamics of love’s contemporary DNA and libidinal techne – practiced in the environment where screens, interfaces, algorithms, data protocols and non-organic objects of affection and affect delineate, organize and program the trajectories of encounter, limerence and erotic pleasure. All the chapters are authored by recognized researchers in the field of love, emotion, media, technology and cultural studies, and they critically explore various aspects of love/intimacy under technocracy, approaching them with expertise the goes beyond the typical high-modernist and post-structural reading of the media-ridden life practices and environments. More importantly, the collection includes landmark works of new media art coming from prominent new media artist gathered around 'Data Dating' – new media art exhibition, curated by Valentina Peri (co-editor of the collection) and presented in Paris, Tel Aviv and London. As such, the collection proffers a unique and original critical approach – one that combines artistic practice and cultural criticism – to comment upon the transformation of human relationships and emotional standards under technological development with reference to the social change and cultural condition. The collection of essays, each accompanied by a work of media art, that provides a comprehensive insight into the construction of love and its practices in the time of digitally mediated relationships. Primary readership will be among educators, researcher and students in disciplines including cultural studies, media and communications, philosophy, sociology, psychology and gender, LGBTQ+ and sexual studies. It will be an extremely valuable resource for those in these fields. It will be of interest to other groups including art curators, online platform designers, social media content managers and designers and data specialists.

Read more less

'Hugely enjoyable' Steve Cavanagh'Ridiculously entertaining' Tom Hindle'I didn't want it to end' Heidi Perks______________________*NUMBER ONE SUNDAY TIMES BESTSELLER**RICHARD & JUDY BOOK CLUB PICK*ONE MURDER. ONE IMPOSSIBLE CASE. WHO IS GUILTY?When hero policeman Grant Cliveden dies from a poisoning in the Old Bailey, it threatens to shake the country to its core.The evidence points to one man. Jimmy Knight has been convicted of multiple offences before and defending him will be no easy task. Not least because this is trainee barrister Adam Green's first case.But it will quickly become clear that Jimmy Knight is not the only person in Cliveden's past with an axe to grind.The only thing that's certain is that this is a trial which will push Adam - and the justice system itself - to the limit. . .** ROB RINDER'S SECOND ADAM GREEN NOVEL, THE SUSPECT, IS AVAILABLE TO PRE-ORDER NOW.**______________________What readers are saying about THE TRIAL:'This is a courtroom cracker''Brilliantly plotted with enough twists and turns to keep you guessing''The courtroom scenes and interactions are electric''It's a must read and hope there will be a sequel - loved it!''Rinder's own career as criminal barrister shines through'Praise for THE TRIAL: 'Strong storytelling with a murder mystery at its heart makes it one to treasure' Daily Mail'A pacy and gripping read!' The Sun'An exciting start to what promises to be an excellent series, with an appealing central character' The Guardian'Such fantastic characters and such a fun read. I loved it' Phillipa Perry'This is a book that takes you to the dark heart of the criminal justice system... I haven't enjoyed a legal thriller this much since Grisham's The Firm' Tony Parsons'A terrific, pacy read' Susanna Reid'A brilliant rollercoaster of a read' Louise Minchin'The Trial is in the best tradition of John Mortimer's Rumpole series. A hugely enjoyable Britishcourtroom drama' Steve Cavanagh'Rinder's personal experiences as a barrister shine through in a cracking courtroom drama packed with tension and sharp wit' Sunday Express'A classic whodunnit with a sensational twist' The Independent'Energetic, warm, laced with humour with a truly inventive mode of murder' Sarah Vaughan'Brilliant courtroom drama, humorous as you would expect from Rob, and one that I had to read slowly because I did not want it to end' Heidi Perks'This one will have you hooked' Glamour'The Trial is whip-smart, stylish and gripping, both murder mystery and courtroom drama, shot through with tension, humour and a dark dissection of corruption, status and justice' Gilly Macmillan'A ridiculously entertaining whodunit. The Trial is sharp, witty and has a huge amount of heart' Tom Hindle'Rob Rinder has penned his first novel, a legal thriller, and it doesn't disappoint' Jewish News 'An engrossing read by someone who clearly knows their subject matter well. I didn't see the ending coming!' Faith Martin'The book is gripping from the first page' Northern Echo'A classic whodunnit with a sensational twist' Yorkshire PostNumber 1 Sunday Times bestseller, July 2023Richard and Judy Book Club Pick, January 2024

Read more less

The focus of published narrative on the great Chinese urbanization wave was always going to sharpen - away from the general fascination, assertions, theories and commentaries to specific issues and specific regions. Well here is a first class example of the next generation of urban china books, focusing on topic and city. Chengdu, a city on the foothills of the Himalayas in Western China, has enacted a bold experiment with the institutions and organizations that shape urban-rural interactions. The world, not just China, should be interested in the results as a city-region multi-level government hierarchy grapples with new models for harmonizing property rights between urban and rural areas, allocating government competencies to appropriate levels, constructing strategic infrastructure; and by these and other means, attempts to coordinate growth of urban activities into the countryside while preserving agricultural capacity. Ye and LeGates do a fine job in marshaling data and making sense of it through clear text and compelling arguments. A must read for students and researchers of urban China.'- Chris Webster, University of Hong Kong'This extraordinary case study of Chengdu, China breaks new ground in the understanding of 21st century urbanization. Its detailed coverage of critical policy changes and practice illuminates our understanding of the rapid changes and important adaptive responses that China has forged to accommodate massive demographic and economic shifts that this country and many others around the world are experiencing. Its impeccable scholarship and clear explanations make this book the key guide and authoritative reference on this topic.'- Eugenie Birch, University of Pennsylvania, USThis detailed study offers a succinct yet comprehensive introduction to China's crucial policy to coordinate urban and rural development. It describes the theoretical, political, and economic reasons why China allowed a large gap between urban and rural incomes, public services, and quality of life to emerge, and the recent national and local government efforts to narrow this inequality.The authors draw primarily on extensive field research and experience in Chengdu, China's leading pilot region for the policy. They describe and explain Chengdu's governmental, administrative, economic, political, and planning system reforms and their accomplishments in clarifying land use rights, rationalizing industrial zones, modernizing agriculture, implementing regional planning, and equalizing infrastructure and services. Coordinating urban and rural development is one of the most pressing problems facing developing countries today. This book places China's experience in context and explains what other cities in China and throughout the developing world can learn from Chengdu as they develop and urbanize.This important book will appeal to academics and policymakers interested in urban planning, economics and development in China, Asia, and elsewhere. It will undoubtedly become an indispensable resource for urbanizing countries throughout the world.Contents: Preface 1. Urban-Rural Development in an Urbanizing World 2. China's Urban-Rural Relationships and National Modernization 3. The Chengdu Model of Coordinated Urban Rural Development: Framework and Strategy 4. Governance and Public Administration Reform 5. Urban and Rural Planning and Development in Chengdu 6. Equalizing Public Services 7. Grassroots Democracy: The Foundation of Rural Modernization 8. Functional Zones and Economic Growth 9. Restructuring Land, Labor, and Capital Markets 10. Chengdu Experience's Value for China and the Challenges for its Wider Application 11. What the World Can Learn from Chengdu 12. Conclusion Appendix: Concepts and Terms Related to Coordinated Urban-Rural Development References Index

Read more less

Wie gestaltete sich das soziale Zusammenleben zwischen Menschen und nichtmenschlichen Arten als eine eng verwobene Gemeinschaft in prähistorischer Zeit? In verschiedensten Disziplinen der Geistes-, Sozial- und Lebenswissenschaften werden verstärkt gesellschaftliche Grundannahmen über nichtmenschliche Arten hinterfragt. Die aus dieser Wende entstandenen neuen Fragestellungen verbreiten sich auch in der Archäologie. Archäolog*innen haben begonnen, traditionelle Ansätze zu überdenken, um Beziehungen zwischen Menschen und (anderen) Tieren in all ihrer Diversität zu erforschen. Im Zuge dieses Perspektivwechsels in der Erforschung von Mensch-Tier-Verhältnissen intensiviert sich auch die Auseinandersetzung mit sozialen, politischen und ideologischen Dimensionen verschiedener Lebensweisen in frühen Gesellschaften. Wir erkennen zunehmend, welche zentrale Rolle Mensch-Tier-Beziehungen bei der Gestaltung und Konstruktion auch prähistorischer Gesellschaften eingenommen haben.In diesem Band wird das gängige archäologische Narrativ von Tieren als passiver, ausbeutbarer Nahrungsressource in Frage gestellt. Damit zeichnet das Buch ein komplexes Bild prähistorischer Mensch-Tier-Verhältnisse. Es legt eine multiperspektivische Studie zu soziokulturellen Praktiken und Vorstellungen damaliger Menschen anhand der spätneolithischen (ca. 6200-5600 v.u.Z) und frühäneolithischen (ca. 4800-4350 v.u.Z.) Siedlung Monjukli Depe im heutigen Turkmenistan vor, die sich von gegenwärtigen westlichen Kategorisierungsformen der Beziehungen zwischen Menschen und Tieren deutlich unterscheiden. Auf Basis einer umfangreichen Sammlung von rund 53.000 Tierknochen aus den Ausgrabungen in Monjukli Depe verfolge ich als analytischen Untersuchungsrahmen einen integrativen Ansatz, der 1.) die archäozoologische Untersuchung der faunalen Überreste, 2.) die Analyse der zoomorphen Repräsentationen als miniaturisierte Tonobjekte sowie 3.) Multi-Isotopenanalysen am ausgewählten Skelettmaterial kombiniert.Das Werk zeigt Wege auf, natur- und kulturwissenschaftliche Sichtweisen in einem analytischen Spektrum an Methoden so zu integrieren, dass Interspezies-Relationen in vergangenen Gemeinschaften holistischer und damit realistischer als bislang rekonstruiert werden können. Die Neubetrachtung der Gemeinschaft als Interspezies-Gebilde stellt den innovativen Ansatz schließlich in einen gesellschaftspolitischen Rahmen. Der Band bietet damit auch einen Referenzrahmen für multiperspektivisch ausgerichtete Untersuchungen von Interspezies-Relationen.English AbstractHow did the social coexistence of humans and non-human species contribute to the formation of interwoven communities in prehistoric times? In various disciplines in the humanities, social and life sciences, assumptions regarding non-human species in societal contexts are coming increasingly under scrutiny. The new questions arising therefrom are spreading into archaeology, where scholars have started to rethink traditional approaches and explore practices, interactions, and relationships between humans and (other) animals. As part of this shift in perspective, more attention is being paid to social, political, and ideological dimensions of lifeways in early societies. With it comes a growing recognition that human-animal relationships occupied a central place in shaping and constructing societies throughout human history.This book presents a multi-perspectival study of socio-cultural practices and conceptions of the people who lived in the prehistoric settlement of Monjukli Depe (Turkmenistan). These differ significantly from contemporary Western categorizations of human-animal relations. Based on a collection of over 50,000 animal remains from the excavations at Monjukli Depe, I pursue an integrative approach that includes 1) zooarchaeological studies of faunal remains, 2) analyses of zoomorphic representations in the form of miniaturized clay objects, and 3) multi-isotopic analyses of selected skeletal material.I suggest ways to integrate scientific and socio-cultural perspectives into an analytical spectrum of methods, enabling interspecies relations in past communities to be reconstructed more holistically and thereby more realistically than has previously been the case. The volume provides a work for future investigations of interspecies relations in other geographic and temporal contexts.

Read more less

"Going to University is an exciting time but it can also feel scary and overwhelming. This excellent guide helps demystify some of the technicalities, so students can easily navigate the system… Recommended reading for anyone keen to make the most of this brilliant life opportunity."Lynda Brady, Pro Vice Chancellor (Student Experience), Edge Hill University, UK.“… It is clear the authors have considered the transition to university life from a range of perspectives, not just an academic one, which is particularly helpful for the challenges students face entering higher education.”Christie Pritchard, Student Learning Manager, University of Plymouth, UK.“This book is a must read… There is something in it for everyone who wants to start university, just started or is already there.”Nils Lenoch, Copenhagen Business Academy, Denmark.“In this book Catherine O’Connor with Liz Thomas’ shares an honest and direct message about life as you begin University and leave as a graduate... from this book you can learn all the tips and tricks on how to manoeuvre University life for the first time.”Fiona Nashie, University of Westminster, UK.“The past year or so has been a challenging time for students and teachers alike. Many of the skills needed to survive university life have gone unused for a multitude of students around the world. I believe that this book will be very useful for students who could not attend their first year on campus… The author highlights all the essential skills that will be required to achieve a satisfying experience at university. It has been very useful to me personally in dealing with any anxiety, or apprehension, regarding starting higher education due to the extended time away from social interactions with various people that are crucial for personal, and professional development.”Sherdil Asif, Student, University of Westminster, UK.Surviving your First Year at University is the ideal companion for new and existing students who want to get the most out of their university experience. Whether you are worried about money, mental health, time management or organising your course load this handy book is packed with advice on how to make the most of your degree. O’Connor and Thomas share their wisdom on topics including:•Understanding and navigating the university system•Coping with social and cultural change •Overcoming the challenges of living away from home•Creating opportunities for personal growth•Using your degree as a platform for your career aspirations•Special tips for International students•Maintaining physical and mental well-being The book describes in detail how a university works and what to expect in day-to-day life there. There are practical tips on coping with academic demands, examinations, money management, lifestyle and self-care.This text is an invaluable toolkit for all students who want to succeed at university.Catherine O’Connor is an Education Consultant and Author, with 25 years’ experience in the university sector at Trinity College Dublin and Dublin City University, Ireland. She is a regular contributor to the media and a subject expert on transition to higher education, career development and the future of work.Liz Thomas is a researcher and consultant in the field of higher education with over twenty years’ experience. Her research focuses on getting into university, experience and success in higher education, and progression to the labour market or further study.

Read more less

This thoroughly revised and updated Fourth Edition of a time-honored text provides the reader with a comprehensive introduction to the field of scanning electron microscopy (SEM), energy dispersive X-ray spectrometry (EDS) for elemental microanalysis, electron backscatter diffraction analysis (EBSD) for micro-crystallography, and focused ion beams. Students and academic researchers will find the text to be an authoritative and scholarly resource, while SEM operators and a diversity of practitioners — engineers, technicians, physical and biological scientists, clinicians, and technical managers — will find that every chapter has been overhauled to meet the more practical needs of the technologist and working professional. In a break with the past, this Fourth Edition de-emphasizes the design and physical operating basis of the instrumentation, including the electron sources, lenses, detectors, etc. In the modern SEM, many of the low level instrument parameters are now controlled and optimized by the microscope’s software, and user access is restricted. Although the software control system provides efficient and reproducible microscopy and microanalysis, the user must understand the parameter space wherein choices are made to achieve effective and meaningful microscopy, microanalysis, and micro-crystallography. Therefore, special emphasis is placed on beam energy, beam current, electron detector characteristics and controls, and ancillary techniques such as energy dispersive x-ray spectrometry (EDS) and electron backscatter diffraction (EBSD).With 13 years between the publication of the third and fourth editions, new coverage reflects the many improvements in the instrument and analysis techniques. The SEM has evolved into a powerful and versatile characterization platform in which morphology, elemental composition, and crystal structure can be evaluated simultaneously. Extension of the SEM into a "dual beam" platform incorporating both electron and ion columns allows precision modification of the specimen by focused ion beam milling. New coverage in the Fourth Edition includes the increasing use of field emission guns and SEM instruments with high resolution capabilities, variable pressure SEM operation, theory, and measurement of x-rays with high throughput silicon drift detector (SDD-EDS) x-ray spectrometers. In addition to powerful vendor- supplied software to support data collection and processing, the microscopist can access advanced capabilities available in free, open source software platforms, including the National Institutes of Health (NIH) ImageJ-Fiji for image processing and the National Institute of Standards and Technology (NIST) DTSA II for quantitative EDS x-ray microanalysis and spectral simulation, both of which are extensively used in this work. However, the user has a responsibility to bring intellect, curiosity, and a proper skepticism to information on a computer screen and to the entire measurement process. This book helps you to achieve this goal. Realigns the text with the needs of a diverse audience from researchers and graduate students to SEM operators and technical managers Emphasizes practical, hands-on operation of the microscope, particularly user selection of the critical operating parameters to achieve meaningful results Provides step-by-step overviews of SEM, EDS, and EBSD and checklists of critical issues for SEM imaging, EDS x-ray microanalysis, and EBSD crystallographic measurements Makes extensive use of open source software: NIH ImageJ-FIJI for image processing and NIST DTSA II for quantitative EDS x-ray microanalysis and EDS spectral simulation. Includes case studies to illustrate practical problem solving Covers Helium ion scanning microscopy Organized into relatively self-contained modules – no need to "read it all" to understand a topic Includes an online supplement—an extensive "Database of Electron–Solid Interactions"—which can be accessed on SpringerLink, in Chapter 3

Read more less

If you loved From Lukov with Love - the sensational TikTok hit that captivates readers all over the world - then you don't want to miss any of Mariana's unique romances. No one writes slow burn like Mariana Zapata and her millions of fans agree! 'Everything Mariana writes is pure gold, and I credit her for my undying love of some of my favorite tropes: slow-burn, enemies to lovers, and grumpy/sunshine...Mariana is an absolute rockstar and a true gift to romance readers everywhere!' - Ali Hazelwood, New York Times bestselling author of The Love Hypothesis'When I need a guaranteed five-star, slow burn romance, I pick up Mariana Zapata every time.' - #1 New York Times Bestselling Author Tessa Bailey'An absolute binge-compelling, subtle, sweet and unforgettable-Zapata brings the heady, dizzy rush of the slow fall into love to the pages of The Wall of Winnipeg and Me. Winnipeg is so much more than a slow burn, a sports story, or a grumpy/sunshine delight-it's all of those things rolled into an unputdownable feast of romance.' - Sierra Simone, USA Today bestselling author of Priest and Misadventures of a Curvy Girl.........................................Vanessa Mazur knows she's doing the right thing. She shouldn't feel bad for quitting. Being an assistant/housekeeper/fairy godmother to the top defensive end in the National Football Organization was always supposed to be temporary. She has plans and none of them include washing extra-large underwear longer than necessary.But when Aiden Graves shows up at her door wanting her to come back, she's beyond shocked.For two years, the man known as The Wall of Winnipeg couldn't find it in him to tell her good morning or congratulate her on her birthday. Now? He's asking for the unthinkable.What do you say to the man who is used to getting everything he wants?More dazzling praise for The Wall of Winnipeg and Me:'A seriously addictive slow burn romance. This book was seriously perfect.' ⭐ ⭐ ⭐ ⭐ ⭐ reader review'This one just really hit the spot for me. Great characters, slow burn romance, funny interactions, and when the heat finally hits, it's delicious. I read straight through the night and have thought about Aidan all day' ⭐ ⭐ ⭐ ⭐ ⭐ reader review'I laughed. I cried. I laughed some more. I cried even harder. I swooned and cried some more . . . This author has giving me back my love for reading and I couldn't thank her enough' ⭐ ⭐ ⭐ ⭐ ⭐ reader review'The character development and the build of the relationship between these two were done perfectly. It was all just beautiful' ⭐ ⭐ ⭐ ⭐ ⭐ reader review'I really enjoyed this slow burn romance. . . The payoff was perfect - I constantly had a cheesy grin on my face. The characters, the story, it was all simply wonderful' ⭐ ⭐ ⭐ ⭐ ⭐ reader review'Slow burn. So good. Didn't want it to end. What a romance!' ⭐ ⭐ ⭐ ⭐ ⭐ reader review........................................Want more of Mariana's delicious slow burn? Why not start with her sensational hit, From Lukov with Love! And don't miss any of her romances beloved by millions of readers!When Gracie Met the GrumpDear AaronLingusRhythm, Chord & MalykhinThe Best ThingUnder LockeKultiWait for ItLuna and the LieHands DownAll Rhodes Lead Here

Read more less

Lisa Clark's scholarly account of the development of the organic movement in the United States and Canada beautifully explains the decades-long transition from understanding organic production as inextricably tied to healthy soils, communities, and social justice ('process-based') to views of organics as meeting certain standards for marketing purposes (product-based). Read this book and you will care deeply about the difference in these views as well as understand current debates about the future of organics.'- Marion Nestle, New York University, US and author of What to Eat'In this fascinating book, Lisa F. Clark presents the history of organic food in North America, from its early roots as a marginal farming activity to its well-established position in today's food market. She analyses political institutions, social movements and corporate actors in how they deal with the delicate question of balancing the search for increasing the market for organic food while maintaining broad organic values. Without offering simple answers to this question, Clark offers important insights into the different approaches to this question. This book is very interesting and highly relevant for anyone interested in organic food in North America and beyond.'- Peter Oosterveer, Wageningen University, the Netherlands'In a globalized food system that struggles to connect the environmental, social, economic and governance dimensions of sustainability, this book provides precious insights. It documents the birth, development and 'mid-age crisis' of the organic movement in North America. The historic lack of clarity between organic principles and practices, and especially the insertion of the organic sector into the global trade regime, have left behind the process-related goal of organic production. Seventy years of lessons, ebbs and flows of a movement searching for an authentic future. A must read for all those interested in sustainable agriculture, institutional challenges faced by value-based movements and visioning organic agriculture pathways.'- Nadia El-Hage Scialabba, Food and Agriculture Organization of the United Nations, ItalyThe Changing Politics of Organic Food in North America explores the political dynamics of the remarkable transition of organic food from a 'fringe fad' in the 1960s to a multi-billion dollar industry in the 2000s. Taking a multidisciplinary, institutionalist approach that integrates social movement theory, public policy analysis and value chain analysis, it tells the story of how the organic movement responded to the social, economic and political changes brought on by the rise of industrial agriculture in the twentieth century.This book examines how the changing constellation of actors, institutions and ideas involved in the politics of organic food influenced the evolving goals and principles of the organic movement, including the muting of social and political organic principles in formal policy and the eclipse of the 'process-based' definition of organic by the 'product-based' definition. It discusses the integration of organic food into the globalized food system and how food and agriculture movements have responded to the forces of industrialization and globalization, as well as critically analyzing the vulnerability of social movements that do not address market interactions in their mandates.This timely and impactful book is a theoretical and empirical resource for researchers and advanced students working on organic food, agriculture, comparative public policy analysis, trade policy, institutionalism and social movements, as well as those involved in making food and agriculture policy.

Read more less

This ideal starter text for student nurses in pharmacology is now into its 4th edition. It makes pharmacology less intimidating by focusing on the knowledge needed at pre-registration level in order to safely and competently practice as a newly qualified nurse.Praised for its helpful layout and jargon-free language, this updated edition introduces pharmacology in a friendly, informative way, without assuming previous knowledge or a level of confidence in numeracy. This new edition has been carefully expanded to include new chapters on cardiovascular pharmacology and chemotherapy in cancer nursing. There are more details on drugs used in chronic and long-term conditions applied to nursing competencies and standards. It incorporates the new 2018 NMC standards for nursing education and links to practice guidelines. Additional case scenarios have been added spanning all areas of practice and include adult, elderly care, child, mental health and learning disability applications. This allows nurses to apply their knowledge to a range of different people with varying and complex needs to enhance their application to practice.The book contains:• 120 calculations and 130 multiple choice questions to assist you in assessing your learning as you work through each chapter• Clinical tips boxes linking pharmacology to nursing practice• 50 person centred case scenarios across a range of practice settings• References to key standards and guidelines"The book also emphasises the application of the principles of pharmacology to all areas of practice and includes; drug action, drug interactions, side effects and adverse reactions. It is useful for all pre-registration students and those on post qualifying or continuing professional development courses where pharmacology is a component.Overall, this book is an excellent resource for healthcare students that will support their learning throughout their training and beyond. It covers fundamental concepts of how the major classes of medications exert their therapeutic effect, but also how side effects and adverse reactions can occur. Chapters on legal aspects of medication administration and drug calculations enhance this usefulness of this book – all of which are supported by example questions, calculations and clinical ‘tips’. This book has been fully updated to reflect the 2018 NMC standards and as such provides a one-stop shop for any students studying safe administration of medications."Dr Andy Powell, Physiology Lead for Nursing Birmingham City University"The outlay of the chapters is easily navigated and the level of the knowledge that the book starts at is at a basic level enough for any student nurse from year 1-3 to start with and builds in complexity. They are in lovely bite-size chunks that are easy to read and easily understood. The 10 MCQ’s at the end of a chapter are a very useful method of chapter consolidation and the case studies further reinforce learning."Georgina Cox, Senior Lecturer in Adult Health Middlesex UniversityDeborah Robertson is a lecturer in nursing at the University of Salford. She teaches on the pre-registration nursing curriculum as well as being involved in post qualifying and post graduate education. She is also author of Essentials of Medicines Management for Mental Health Nurses.Paul Barber was a Senior Lecturer at the University of Chester. He is co-author of Further Essentials of Pharmacology for Nurses (2012) and contributor and editor of Medicines Management for Nurses: Case Book (2013), all Open University Press. He is now retired.

Read more less

"This magisterial volume will be the definitive study of the economics and history of the chemical industry for many years to come. The core of the volume is a study of the process of innovation in the first industry to employ science as a basis for technology. This extends over 150 years and covers four leading countries-Britain, Germany, Japan, and the United States. . . . The book will be of interest to participants in the industry, economists, and economic historians interested in growth, business school faculty and students concerned with corporate strategy, especially the management of technical change, and finally, policymakers who create the legal and political environment within which the industry has developed."-Dale W. Jorgenson, Frederic Eaton Abbe Professor of Economics, Harvard University "The chemical industry will continue to be a leading indicator of economic development in the century ahead. The research and conclusions of Ralph Landau and his colleagues capture the structure, processes, and future of the industry and make [this] book required reading for all who follow the field." -Frank Popoff, Chairman, The Dow Chemical Company "Given the magnitude and pervasiveness of the chemical processing industry which underlies all manufacturing, this study of the dynamics of interactions among technology, economics, and politics should become must reading for all serious students of industrial development." -S. Allen Heininger, Past President, American Chemical Society "A painstakingly thorough and insightful analysis of the global chemical industry. . . . It will be of great value to economic historians and economists concerned with the growth of modern industrial societies. It is must reading for executives and scholars concerned with innovation and competitiveness." -David J. Teece, Director, Institute of Management, Innovation & Organization Mitsubishi Professor, Walter A. Haas School of Business, University of California, Berkeley "The innovativeness of the chemical industry has made it a key player in the development of the modern world economy. Analysis of the industry's long-term growth therefore gives an insight into the interaction between science, technology, and economic progress, as this book demonstrates. At the same time, the analysis offers observations that are of great practical relevance to today's issues." -Professor Doctor Gottfried Plumpe, Bayer Corporation The chemical industry has been one of the world's best managed and most consistently successful business performers for 150 years. Now, drawing together fourteen of the most respected economists and industry experts, the editors of Chemicals and Long-Term Economic Growth present one of the most extensive studies of this industry in order to uncover the secrets behind this remarkable track record. With economic and managerial insights supported by specific real-world examples, this book shows how the development of the chemical industry can provide insights for achieving and sustaining economic growth. Scientists and business leaders in the chemical industry and many other technological fields, and economists generally, may benefit from the history and analysis presented in this book. This book examines: * The role of science, innovation, technology, and organization in creating economic growth and profits * Chemical industry growth in Germany, Britain, the United States, and Japan, including an analysis of relative strengths and weaknesses * The impact of macroeconomics, legal and financial institutions, corporate finance, and other policies and institutions on the behavior of chemical companies * The principle of comparative advantage-why certain industries excel in certain areas.

Read more less

Tom de Freston (born 1983) is a British artist and writer, living and working in Oxford. De Freston’s multimedia art tackles themes of trauma, humanity and intimacy across paintings, films and performance. He builds rich visual narratives, drawing on literature, art history and social issues. He graduated from Cambridge University in 2007 and since 2008 has exhibited his work in over twenty shows to date. A prolific author, Granta published de Freston’s debut non-fiction book, Wreck, in 2022 and his second will be released in 2024. Julia and the Shark (Hachette, 2021), created with his wife Kiran Millwood Hargrave, won the Waterstones Children’s Gift of the Year and was shortlisted for the Wainwright Prize for Children's Writing on Nature and Conservation. De Freston was chosen to illustrate the twenty-fifth-anniversary edition of David Almond’s Skellig, published in 2023.I Saw This was born out of a collaboration between de Freston, filmmaker Mark Jones and Dr Ali Souleman after de Freston was introduced to the academic in 2017. The paintings and mixed-media works that resulted from the project are an exploration into Souleman’s experiences of terrorism, displacement and war in Syria and ruminate on how art can attempt to represent suffering and terror. In 1996, a bomb explosion in Damascus on New Year’s Eve nearly killed Souleman and left him blind. A sensitive and highly-charged topic, Souleman explained to de Freston the importance of engaging with what is happening in Syria. Disembodied mouths, hands and feet appear frequently in the works. Circles recur as a motif, which bear an uncomfortable resemblance to eyes and eye sockets. In the Mirror paintings which stand upright in black boxes, de Freston embeds ash, screws, thick glue, dirt and bits of wood into the canvas. They are corporeal and volcanic, visceral and abstract. The sense of molten heat in the paintings was compounded by a fire in de Freston’s studio in 2020, which was simultaneously destructive while giving the artist and the collaboration new momentum.The singular artistic process between the three men involves de Freston describing the paintings to Souleman through words and touch. Souleman brings fresh meaning to the works by reading them in new ways, grounding them in his psychological landscape. Mark Jones captures these interactions in striking photographs and film footage. The collaborators’ close relationships, with each of their practices feeding into the others’, shine through.Habda Rashid, Senior Curator of Modern and Contemporary Art at Kettle’s Yard and the Fitzwilliam Museum, introduces I Saw This and considers the challenges and significance of incorporating elements from real life. Journalist Yasmina Floyer’s contribution describes her reaction to de Freston’s work at his From Darkness exhibition at No 20 Arts, where she found that the sooty-black feet stencils and inky circles depicted resonated with her own experience of child loss. The moving text shows how de Freston’s art carries both specific and universal meanings. Editor Matt Price elaborates on the collaborative process and identifies layers of symbolism across the project, structuring his essay with fascinating quotes from Abu al-Ala al-Ma’arri, the eleventh-century blinded Arab philosopher. Crucially, de Freston, Jones and Souleman’s voices are present in the book, with each shedding light on their part in the project. De Freston’s art is rooted in empathy and I Saw This is a culmination of this, successfully translating Souleman’s world of memory and metaphor.

Read more less

Au sortir de la Seconde Guerre mondiale, des millions d’étrangers se trouvent sur le sol allemand : anciens travailleurs forcés, rescapés des camps nazis ou déracinés aux profils multiples. La plupart d’entre eux sont rapatriés après la capitulation allemande, mais presque un million de personnes déplacées (Displaced Persons – DPs), effrayés par l’antisémitisme à l’Est de l’Europe, ou redoutant la montée des régimes communistes, refusent de rentrer dans leur patrie. C’est donc dans les trois zones occidentales de l’Allemagne occupée, exsangue et traversée par des flux incessants, que les DPs vivent pendant plusieurs mois ou années. Leur histoire est multiple et ils en sont à la fois les objets et les acteurs. Cet ouvrage, rassemblant des contributions en trois langues (français, anglais, allemand), croise les perspectives entre histoire politique et internationale, histoire des migrations, analyses culturelles et études des représentations. Il permet de saisir les interactions entre les décisions internationales, les impératifs des pays d’origine des DPs mais aussi ceux des pays d’immigration, les réalités de l’Allemagne occupée et les besoins et espérances des DPs eux-mêmes. Entre sortie du conflit mondial et début de guerre froide se nouent autour des DPs les grandes problématiques politiques et humaines qui forgent l’histoire des déplacements et du refuge. In the aftermath of the Second World War, millions of foreign civilians found themselves in the German territory. Among them, there were former forced laborers, survivors from the Nazi camps, many uprooted migrants who had all experienced the war in different ways. Most of them were repatriated after the German capitulation. However, almost one million of these «Displaced Persons» (DPs) refused to go back to their homeland. They were scarred by anti-Semitic violence, or by the rise of communist regimes in Eastern Europe. For a few months, even a few years, they remained mostly in the Western zones of occupied Germany, facing the harsh post-war conditions of defeated Germany. DPs became both targets and actors of global politics dealing with the refugee problem. This book puts together articles in three languages (French, English, and German). The contributions reveal the DPs’ history from different points of view. They rely on the history of international relations at the end of the war and of the various states involved in the DP question, as well as on social and cultural studies. The diversity of methodological patterns allows for a broad comprehension of this singular story at different scales, from the international debates and tensions to the needs and the hopes of the DPs themselves, in the social and political context of post-war occupied Germany. As the end of the war led to the Cold War, the DP question raised most of the political and humanitarian issues that would continue to interfere with the management of population displacements and refugees until the present day. Am Ende des Zweiten Weltkrieges befanden sich einige Millionen Ausländer auf deutschem Boden: ehemalige Zwangsarbeiter, Überlebende der NS-Lager und andere entwurzelte Personen. Die meisten von ihnen kehrten nach der deutschen Kapitulation in ihre Heimat zurück; zurück blieben hingegen fast eine Million Displaced Persons (DPs), die den Antisemitismus in Osteuropa oder den Aufstieg der kommunistischen Regime in diesen Ländern fürchteten, so dass sie sich weigerten, in ihre Ursprungsländer zurückzukehren. Sie fanden sich schließlich für mehrere Monate oder gar Jahre in den drei westdeutschen Besatzungszonen wieder, die von den Kriegsfolgen gezeichnet waren und mehrere Millionen von Flüchtlingen aufnehmen mussten. Ihre Geschichte ist vielfältig; bisweilen wird

Read more less

Chinaka Hodge came of age along with hip-hop--and its influence on her suitors became inextricable from their personal interactions. Form blends with content in Dated Emcees as she examines her love life through the lens of hip-hop's best known orators, characters, archetypes and songs, creating a new and inventive narrative about the music that shaped the craggy heart of a young woman poet, just as it also changed the global landscape of pop. Praise for Dated Emcees: "In the old tellings hip-hop was a woman, a certain kind--one needing, even begging to be saved. In Dated Emcees, Chinaka Hodge gives her a voice and she tells of her loves and desires, her traumas and pains in words as hard, as lit, as loving, cunning, cutting, ecstatic, as tender and devastating as her big world requires. This is poetry that, in its infinite power and intimate grace, will still turn in your mind long after the music is over."--Jeff Chang, author of Who We Be: A Cultural History of Race in Post-Civil Rights America "Hodge writes with an unpredictable, rare honesty. This collection quietly and simply illustrates love in a complicated world." --Donald Glover AKA Childish Gambino "This is an absolute powerhouse of a book, and a new pinnacle for Chinaka Hodge. There's enough beauty and heartbreak and melancholy and humor and sorrow in here for three collections, or two lifetimes. Hodge's writing is so incredibly specific but somehow universal, so honest and raw but somehow polished to unimproveability. She deserves a wide audience, an attentive audience, an audience that wants to be astounded."--Dave Eggers, author of The Circle "Chinaka Hodge is hands down, unequivocally, my favorite writer of words. All day. Every day. She writes with the grace of a dancer, the bars of a rapper, the heart of your best friend, and all of the swag and soul of Oakland. Dated Emcees made me cry. And I don't really do that. It doesn't use Hip Hop as a lens. It is Hip Hop. In the way that we, who have grown up with rap as our brilliant, estranged, mythological, abusive lover/father/son, are all Hip Hop. Aware of his flaws, and his potential. And loving him unconditionally. These are poems to read every day. To make mantras from. They are the best poems you've ever read." --Daveed Diggs, Actor/Rapper, star of Hamilton on Broadway "Every time I hear new work from Chinaka Hodge I wonder if she was always this good. She was, I'm pretty sure. And yet somehow, she's leveled up again. Dated Emcees is a dropped microphone, and a direct challenge to anyone listening. Step your game up."--George Watsky, author of How to Ruin Everything: Essays "Ms. Hodge's collection complicates dogmatic notions of feminist principles and hip hop pathologies. She is the steward of a candid and sonorous new form, a lyrical journalism expressed in a meter that climbs from West Oakland's Bottoms to the peak of a Wonder-laced rocket love. Dated Emcees is outlined in the matter of black life, streamlined through the filter of black womb ...a smoke-filled lung in a sweat-filled club of safety and danger, and the bass of black moon."--Marc Bamuthi Joseph, arts activist, spoken word artist, US Artists Rockefeller Fellow

Read more less