Search results for ""author mike""

An increasing number of universities around the globe are rewarding faculty who place their work in top management journals. Drawing on the insights from top journal editors and leading scholars in the field, this book is a treasure trove of tips for publishing in the best management journals. The topics covered include the mysteries of the review process, getting your methodology right, publishing across disciplinary boundaries, the rise of open access journals, publishing ethics, making use of peer review, targeting special issues, sustaining a publications career, and making sense of journal rankings. Drawing on the considerable experience of its authors, and offering candid insights that are often held as secrets among senior faculty, this book takes the reader behind the scenes of the journal review process, making it a must-read for those seeking to advance their career.Contributors: P. Andries, Y. Baruch, D.D. Bergh, S.K. Bhaumik, B.K. Boyd, M.R. Buckley, P. Budhwar, T. Clark, J.G. Combs, D. Cumming, S. Estrin, G.R. Ferris, D. Gioia, B. Harley, M.A. Hitt, G.P. Hodgkinson, R.D. Ireland, F.W. Kellermanns. D.J. Ketchen Jr., B.T. Lamont, A. Leiponen, B.R. Martin, W. Mitchell, T. Pederson, P.L. Perrewé, A.L. Ranft, P.L. Roth, A.D. Smith, C.C. Snow, W.H. Starbuck, W.H. Stewart Jr., S. Tallman, S. Toms, R. Van Dick, G. Wood, M. Wright, D.W. Yiu

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Sport Public Relations, Third Edition With HKPropel Access, offers a comprehensive examination of the value and practice of public relations in sport. Extensively updated and substantially reorganized, this third edition reflects the evolution of the field with modern applications across a wide range of media channels. The book’s topics align with the Common Professional Component topics outlined by the Commission on Sport Management Accreditation (COSMA). The author team brings together significant professional and educational backgrounds in sport public relations to offer an engaging look at the full range of public relations functions. Readers will learn the importance of consistent brand communication and how to manage organizational relationships, both internal and external, to attain key strategic goals. The thorough coverage of the field is built around three common themes: Public relations is a managerial function focused on advancing the brand and engaging key stakeholders. The communications environment is continuously evolving. Community relations, employee relations, and donor relations are as critical as media relations within the sport industry. Woven throughout these themes are public relations theories applied in sport-specific contexts to help students further understand the complexity of the sport communication ecosystem. Throughout the book, there is guidance for practical application, including samples of public relations materials such as news releases and employee newsletters. Be Your Own Media sidebars highlight how sport organizations are proactively telling their stories across various media platforms. New to this edition, case studies and discussion questions serve as a foundation for additional learning. Other updates include the following: Discussion of engaging key publics through social media and other forms of digital media—such as blogs, podcasts, virtual fan communities, and video—as well as approaches to developing content, metrics for measuring success, and skills for managing media in sport An examination of customer experience (CX) and how to enhance those relationships by defining customer touch points and mapping the customer journey Considerations for social media usage during crisis communication, with modern examples of effective and ineffective ways prominent sport entities have managed recent crises Also new to the third edition are related online learning aids delivered through HKPropel and designed to generate discussion and highlight the opportunities and challenges that exist in sport public relations. Commentary on current topics is accompanied by links to associated content, discussion questions, and applied learning activities to promote engaged student learning. A live Twitter feed for specific hashtags within HKPropel ensures regular updates. With Sport Public Relations, Third Edition, students will better understand the various demands of the field and learn to successfully and proactively develop consistent communication and stronger relationships between sport organizations and their key publics. Note: A code for accessing HKPropel is included with this ebook.

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It was an age of adventure. An age of sorcery. An age of unrelenting horror. Sword and sorcery and pulp horror go hand-in-hand. Sinister enchanters working foul magic. Hideous beasts lurking in shadowy dungeons. Blasphemous elder gods uncoiling from forgotten and forbidden temples.Swords in the Shadows features twenty-one stories with a bloody stake driven into the heart of both the horror and fantasy camps. Herein, you will find fantasy worlds, brave warriors, fabulous creatures, wondrous magic. But you will also uncover bloodcurdling chills, spine-tingling horror, and an examination of those things that truly terrify.

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The Schuylkill River flows more than 100 miles from the mountains of the Pennsylvania Coal Region to the Delaware River. It passes through five counties - Schuylkill, Berks, Chester, Montgomery, and Philadelphia - and its valley is home to more than three million people, yet few are aware of the hidden ruins and traces left by a pioneering 200-year-old inland waterway: the Schuylkill Navigation. Some of it is literally buried in their own backyards.Often called the Schuylkill Canal, this complex Navigation system actually boasted twenty-seven canals. The first of the anthracite-carrying routes in America, the 108-mile Navigation shadowed the Schuylkill River for nearly all its length. It once had more than thirty dams and slackwater pools, more than 100 stone locks, numerous aqueducts, and the first transportation tunnel in the nation. They were all built by hand starting in 1816.In the 1940s, as part of a massive environmental cleanup of the river, this important and influential infrastructure was largely dismantled - but not entirely. Two short sections of the watered canal get plenty of attention: the Oakes Reach at Schuylkill Canal Park near Phoenixville and the Manayunk Canal in Philadelphia. Both are popular recreational destinations. What happened to the rest of it?Photographer Sandy Sorlien resolved to find out. Over the course of seven years, she traveled upriver repeatedly to bushwhack along the riverbanks and to row and paddle in the river itself. Armed with camera and binoculars, loppers and trekking poles, nineteenth-century maps and modern satellite imagery, and abetted by local historians and an archaeologist, she found all sixty-one lock sites and explored most of the canal beds. Her photographs reveal a mysterious remnant landscape, evidence of a bold industrial innovation that spelled its own demise. The water pollution created by the coal industry and obstructive dams meant the end of a way of life for the towns that boomed along the canals, from Pottsville to Reading, Birdsboro to Phoenixville, Bridgeport to Philadelphia.Along with Sorlien's full-color plates and explanatory essays, Inland features a selection of historic images, rare historic Schuylkill Navigation Company maps, and early Philadelphia Watering Committee plans. The book also includes a foreword by renowned landscape scholar John R. Stilgoe, an essay on regional transportation history by Mike Szilagyi, Trails Project Manager for the Schuylkill River Greenways Natural Heritage Area, and an afterword by Karen Young, Director of the Fairmount Water Works Interpretive Center. A sweeping new Schuylkill River map by Morgan Pfaelzer connects it all. Inland is the first to present contemporary photographs from a survey of the entire Schuylkill Navigation, becoming an essential resource for future historians and a resonant visual history all its own.

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Are you about to start the Foundation Programme? Do you know what to expect and how to thrive? The Hands-on Guide for Junior Doctors, Fourth Edition, is the ultimate, practical guide for junior doctors and medical students. It helps you tackle the emotional, intellectual and physical demands of being a new doctor and allays common insecurities to help you make the most of your time in clinical practice. This book tells you how to prepare for the daily rigours of hospital life, and will help you meet the required standard. It provides advice on getting started in placements, and helps you develop confidence, with tips on what to do as a junior member of the hospital team, and how to deal with common calls and emergencies. There is also an invaluable chapter on how to perform the practical procedures you’ll be assessed on. With the Foundation Programme such a demanding process, both physically and emotionally, this book also provides the kind of information you don’t get at medical school, for example, how to look after yourself throughout your training. Take the stress out of the Foundation Programme with The Hands-on Guide!

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Encourage success in Higher Applications of Mathematics with this accessible Student Book following TeeJay's trusted approach of continuous progression and consolidation. - Provide full coverage of the new specification with four sections covering all components of the course, plus advice on completing the coursework project- Build students' skills with comprehensive explanations and engaging exercises on how to use RStudio (Posit) and Excel, with datasets and demo videos included online- Review previous learning from National 4 and 5 Applications of Mathematics with a 'Chapter 0' at the start of each section- Help students consolidate knowledge with review exercises at the end of each chapter, Exam Practice Papers at the end of the book, plus numerous exam-style questions throughout- Mark students' work easily or encourage independent study with all answers provided in the back of the book, plus full worked solutions and mark schemes for all end-of-section review exercises and Exam Practice Papers available online

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With its beautiful meadows and countless meandering streams, picturesque Parke County, Indiana, is home to 31 historic covered bridges, ranging from 43 to 315 feet long. Every October, the county hosts the Covered Bridge Festival, which draws more than two million people nationwide to the courthouse lawn in Rockville. From there, tourists set off to visit the bridges and to seek out the arts and crafts fairs located in each of the festival's nine communities. Photographer Marsha Williamson Mohr has spent years in the area, capturing spellbinding images of the bridges and nearby farms and the natural beauty of the area, season by season. The warmth and vitality of Parke County brings her back time and time again, and this gorgeous photographic collection will call you back as well.

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Big Cat Phonics for Little Wandle Letters and Sounds Revised has been developed in collaboration with Wandle Learning Trust and Little Sutton Primary School. It comprises classroom resources to support the SSP programme and a range of phonic readers that together provide a consistent and highly effective approach to teaching phonics. Oh no, Farmer Jon has accidentally spilled all but one churn of milk! It's now up to Mark and Fee to get the milk churn to the shop through the thick fog. Will they manage it? Who might help them on their way?

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Collins Big Cat supports every primary child on their reading journey from phonics to fluency. Top authors and illustrators have created fiction and non-fiction books that children love to read. Levelled for guided and independent reading, each book includes ideas to support reading. Teaching and assessment support and eBooks are also available. What is fake news and why is it important? Learn about this modern phenomenon and how to sort the fact from the fiction. Diamond/Band 17 books offer more complex, underlying themes to give opportunities for children to understand causes and points of view. Text type: An information book Ideas for reading in the back of the book provide practical support and stimulating activities. Curriculum Links: PSHE

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Help your students make good progress in Key Stage 3 English with our popular series, now updated for the new curriculum. The Aiming for series provides targeted support for all ability levels to help every student move forward from their achievement at Key Stage 2 towards GCSE success. This revised edition of Aiming for Level 5 Writing offers student-friendly explanations and activities to build, develop and extend students’ literacy skills, showing them precisely what they need to do to progress. Whether you're looking for a one-off lesson, snappy starters or a longer programme of study, these flexible resources are designed to fit around the needs of your teaching and your classes. Now refreshed to reflect the text types and skills in the new Key Stage 3 curriculum, the Writing and Grammar books also offer comprehensive coverage of the grammar objectives set out in the appendix to the Key Stage 2 English Programme of Study. This Aiming for book is the perfect starting point for students arriving at secondary school with a secure Level 4 or a low Level 5 in writing. It will help you to target areas of underperformance, with a chapter on each writing skill written at the right level by experienced teachers and consultants develop the essential writing and grammar skills, with clear, accessible explanations, inspiring examples and lively follow-up activities build confidence in grammar to improve students’ writing by exploring the effects of other writers’ choices motivate and engage students, with exciting stimulus texts, fresh approaches to learning and a clear, colourful layout embed Assessment for Learning in your day-to-day teaching, with clear learning objectives, criteria for self and peer assessment on every double-page, and end of chapter checklists to help students understand how to progress gather evidence for periodic assessments, with the ‘Apply your skills’ tasks designed to build writing stamina and independence plan ahead without the stress, with ready-to-use double-page lessons and a teacher guide at the back of the book support the transition to Key Stage 3 by reinforcing and building on the writing skills taught at Key Stage 2.

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Build your child’s reading confidence at home with books at the right level Brave Tim agrees to look after Rosa’s pets. He isn't afraid of vultures or wolfhounds, or even giant rabbits. But he isn't so sure about the gorilla, gargling in the kitchen! A comic story with a familiar setting, from Margaret Mahy. Ruby/Band 14 books give increasing opportunities for children to develop their skills of inference and deduction. Text type – Story with a familiar setting. The reader response page consists of a story map to encourage children to retell the story in their own words. Curriculum links – Citizenship: Animals and us; Music: Animal magic, exploring descriptive sounds. This book has been quizzed for Accelerated Reader.

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How do you make the most of the volunteers who give their time to your organisation? Engaging people, giving them a great experience and balancing the needs of your organisation is an essential skill. These are the key strategic issues covered in this comprehensive guide for recruiting, selecting, involving and rewarding volunteers effectively.Ensure you get it right by gaining from the knowledge and experience gathered in this single volume by leaders in their field. This guide captures the essential information anyone managing volunteers. If you've just been given responsibility for volunteers in addition to your main role, or you're a dedicated Volunteer Manager, this book is for you. It will also be useful for other management and senior management roles to understand the work involved in effectively engaging volunteers. It includes: * Current trends in volunteering and how to make the most of current opportunities * How to match the right volunteers to the right roles * Creating a comprehensive volunteering programme * Measuring the impact of volunteering in meeting your aims * How to improve strategy and working relationships for your organisation.

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Mike Gayle: emotions you'll never forget, stories you'll want to shareHelen and Ben parted as heartbroken 18-year-olds and went their very separate ways.Twenty years later, mother-of-two-teenagers Helen is still in Manchester, a part-time primary teacher, stunned by the behaviour of her love-rat husband. In an old T shirt and scruffy jeans, she feels at the lowest point in her life.And suddenly, impossibly, Ben is standing on her doorstep. Tired maybe, lonely even, but clearly still the world-famous, LA-based multi-millionaire rockstar he has become.Can you ever go back?For Helen and Ben, so much has happened in the years between. But just to sit in the kitchen for a while and talk - that would be nice.Before the world comes crashing in.Friendship, love, heartache and hope collide in this unforgettable emotional journey, from the author of Half A World Away.'The escapist pageturner of the summer' The Sunday Times Your favourite writers are already falling in love with this story . . . 'Moving, uplifting, unforgettable. Mike always writes from the heart and creates stories we fall in love with' Lisa Jewell'Full of relatable characters and as Mike takes us on a journey through all their high and lows and we're with them every step of the way . . . A wonderful story' Ruth Hogan'Poignant. Powerful. Beautiful' Milly Johnson'Funny, real and unexpected, a story that will keep you hooked to the very last page' Alexandra Potter Fans love this new story . . . 'I've always been a fan of Mike's books BUT this one is my absolute favourite'⭐⭐⭐⭐⭐'Mike writes so well and creates the best, most memorable characters'⭐⭐⭐⭐⭐'Had me absolutely gripped'⭐⭐⭐⭐⭐'Outstanding. Loved it and devoured every page'⭐⭐⭐⭐⭐

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Stories of the end of civilized life have always fascinated us, from the mythological world endings, Armageddon to Ragnarok, to the flood stories of across the Ancient world. They make us wonder what we would do if all around us came to an end: no transport, no fuel, no communications: a retreat into the desperation, the onslaught of disease, how would we survive? This is the source of zombie literature and provides the inspiration for this fabulous mix of horror and adventure, of classic and brand new writing in the successful series of Gothic Fantasy titles from Flame Tree. New, contemporary and notable writers featured are: Mike Adamson, Bill Davidson, Michael Paul Gonzalez, Michael Haynes, Liam Hogan, Jennifer Hudak, Curt Jeffreys, Su-Yee Lin, Wendy Nikel, Konstantine Paradias, Darren Ridgley, John B. Rosenman, Zach Shephard, Meryl Stenhouse, Morgan Sylvia, Lucy Taylor, Natalia Theodoridou, and Shannon Connor Winward. These appear alongside classic stories by authors such as Stephen Vincent Benét, George Allan England, M.P. Shiel, Jules Verne and H.G. Wells.

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Duke University's head basketball coach Mike Krzyzewski has proved himself a leader both on and off the court. He's led the Duke Blue Devils to five straight Final Four appearances, culminating in back-to-back championships in 1991 and '92. He has received five National Coach of the Year Awards -- and many of the players he coached in college have gone on to NBA stardom! Now Coach K offers the insights he uses to coax peak performances from his team, relying on lessons he learned as a captain in the U.S. Army, sportsmanship, respect, and a genuine gift for leading with the heart.

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The 11+ Verbal Reasoning GL & Other Styles series covers verbal reasoning technique for the GL Assessment 11+ exams, CATs, Common Entrance and scholarship examinations for independent schools, and all other styles of verbal reasoning test. This series of books is designed to be used in sequence from Workbook 1 onwards. The 11+ Verbal Reasoning GL & Other Styles workbook series is complemented by 11+ Verbal Reasoning GL & Other Styles testbooks that reinforce a child's verbal reasoning technique and knowledge, and testpacks for final exam preparation. Answers, Progress Charts and a Certificate of Achievement are included at the end of the book. All our materials have been rigorously classroom tested. The methodologies have been successfully used in AE Tuition classes for over 20 years.

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Suitable for children ages 6-8You have received a crate of rare space objects from around the world, and it’s up to you to place them in the correct rooms! Follow the instructions to create five amazing pop-ups and assemble the objects in a series of exhibitions in the museum. Learn about everything from Mars rovers to Moon rockets. Hands-on, interactive and illustrated with picture book panache by Mike Love, Science Museum is the perfect gift for fans of Space, craft and model making, combining STEAM and creativity in a fun-packed package.Five featured pop-ups: Solar System Saturn and its Rings Lunar Module Mars Rover Perseverance International Space Station Contents: Introduction & Contents Introduction to Space The Solar System Inner Planets Outer Planets Stars and Galaxies Space capsules Space Planes Rovers International Space Station Where in the Universe? and Space Travel of the Future Build Your Own Space Museum is the latest release in Lonely Planet Kids’ successful Build Your Own series which includes Build Your Own Dinosaur Museum, Build Your Own History Museum, and Build Your Own Science Museum.About Lonely Planet Kids: Lonely Planet Kids - an imprint of the world's leading travel authority Lonely Planet - published its first book in 2011. Over the past 45 years, Lonely Planet has grown a dedicated global community of travellers, many of whom are now sharing a passion for exploration with their children. Lonely Planet Kids educates and encourages young readers at home and in school to learn about the world with engaging books on culture, sociology, geography, nature, history, space and more. We want to inspire the next generation of global citizens and help kids and their parents to approach life in a way that makes every day an adventure. Come explore!

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The Drugs Don't Work - A Penguin Special by Professor Dame Sally Davies, the Chief Medical Officer for EnglandIf we fail to act, we are looking at an almost unthinkable scenario where antibiotics no longer work and we are cast back into the dark ages of medicine where treatable infections and injuries will kill once again (David Cameron, Prime Minister) Antibiotics add, on average, twenty years to our lives. For over seventy years, since the manufacture of penicillin in 1943, we have survived extraordinary operations and life-threatening infections. We are so familiar with these wonder drugs that we take them for granted. The truth is that we have been abusing them: as patients, as doctors, as travellers, in our food.No new class of antibacterial has been discovered for twenty six years and the bugs are fighting back. If we do not take responsibility now, in a few decades we may start dying from the most commonplace of operations and ailments that can today be treated easily.This short book, which will be enjoyed by readers of An Inconvenient Truth by Al Gore and Bad Pharma by Ben Goldacre, will be the subject of a TEDex talk given by Professor Dame Sally Davies at the Royal Albert Hall.Professor Dame Sally C. Davies is the Chief Medical Officer for England and the first woman to hold the post. As CMO she is the independent advisor to the Government on medical matters with particular interest in Public Health and Research. She holds a number of international advisory positions and is an Emeritus Professor at Imperial College.Dr Jonathan Grant is a Principal Research Fellow and former President at RAND Europe, a not-for-profit public policy research institute. His main research interests are on health R&D policy and the use of research and evidence in policymaking. He was formerly Head of Policy at The Wellcome Trust. He received his PhD from the Faculty of Medicine, University of London, and his B.Sc. (Econ) from the London School of Economics.Professor Mike Catchpole is an internationally recognized expert in infectious diseases and the Director of Infectious Disease Surveillance and Control at Public Health England. He has coordinated many national infectious disease outbreak investigations and is an advisor to the European Centre for Disease Prevention and Control. He is also a visiting professor at Imperial College.

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Exam board: AQALevel: A-levelSubject: SpanishFirst teaching: September 2016First exams: Summer 2018Maximise your students' potential and build the skills needed to succeed with this exam-focused workbook, packed with practice questions for every section of the AQA A-Level Spanish exams.- Encourage rolling revision throughout the two years by developing your students' skills in class and at home- Test each skill with exam-style activities for every section of the exam papers, with all the audio and answers accessible online- Build your students' confidence in vocab and grammar with focused lists, explanations and activities- Target the top grades with sample answers and tips to boost exam performance

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Making My Pitch tells the story of Ila Jane Borders, who despite formidable obstacles became a Little League prodigy, MVP of her otherwise all-male middle school and high school teams, the first woman awarded a college baseball scholarship, and the first to pitch and win a complete men’s collegiate game. After Mike Veeck signed Borders in May 1997 to pitch for his St. Paul Saints of the independent Northern League, she accomplished what no woman had done since the Negro Leagues era: play men’s professional baseball. Borders played four professional seasons and in 1998 became the first woman in the modern era to win a professional ball game. Borders had to find ways to fit in with her teammates, reassure their wives and girlfriends, work with the media, and fend off groupies. But these weren’t the toughest challenges. She had a troubled family life, a difficult adolescence as she struggled with her sexual orientation, and an emotionally fraught college experience as a closeted gay athlete at a Christian university. Making My Pitch shows what it’s like to be the only woman on the team bus, in the clubhouse, and on the field. Raw, open, and funny at times, her story encompasses the loneliness of a groundbreaking pioneer who experienced grave personal loss. Borders ultimately relates how she achieved self-acceptance and created a life as a firefighter and paramedic and as a coach and goodwill ambassador for the game of baseball.

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As a tribute to scholar and mentor James M. Kauffman and his prodigious influence on the education of children and youth with disabilities, Achieving the Radical Reform of Special Education highlights and examines issues central to the continued growth and maturation of the field of special education. This impressive collection features the issues Kauffman has raised pointedly and repeatedly in his writing over the past three decades. With contributions by prominent scholars, essays throughout the book provide a valuable synopsis of the status of special education and its progress toward the achievement of radical reform at the outset of the 21st century.The volume is divided into four sections, corresponding to the following themes:1) recognizing and responding to individual differences among special education students; 2) repairing and elaborating the historical, philosophical, and legal foundations of special education practice; 3) strengthening the field’s empirical base; and4) confronting problems of advocacy and reform in special education. Chapters within each section discuss the status of the field, its progress, pitfalls, and promising subsequent steps.Achieving the Radical Reform of Special Education is intended for scholars, policy makers, and graduate students in special education and associated disciplines who seek to improve schools and to improve the education of students whose behavior and exceptional learning needs prevent their academic and social development.

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Making My Pitch tells the story of Ila Jane Borders, who despite formidable obstacles became a Little League prodigy, MVP of her otherwise all-male middle school and high school teams, the first woman awarded a college baseball scholarship, and the first to pitch and win a complete men’s collegiate game. After Mike Veeck signed Borders in May 1997 to pitch for his St. Paul Saints of the independent Northern League, she accomplished what no woman had done since the Negro Leagues era: play men’s professional baseball. Borders played four professional seasons and in 1998 became the first woman in the modern era to win a professional ball game. Borders had to find ways to fit in with her teammates, reassure their wives and girlfriends, work with the media, and fend off groupies. But these weren’t the toughest challenges. She had a troubled family life, a difficult adolescence as she struggled with her sexual orientation, and an emotionally fraught college experience as a closeted gay athlete at a Christian university. Making My Pitch shows what it’s like to be the only woman on the team bus, in the clubhouse, and on the field. Raw, open, and funny at times, her story encompasses the loneliness of a groundbreaking pioneer who experienced grave personal loss. Borders ultimately relates how she achieved self-acceptance and created a life as a firefighter and paramedic and as a coach and goodwill ambassador for the game of baseball.

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Built upon the two original books by Mike Crisfield and their own lecture notes, renowned scientist René de Borst and his team offer a thoroughly updated yet condensed edition that retains and builds upon the excellent reputation and appeal amongst students and engineers alike for which Crisfield's first edition is acclaimed. Together with numerous additions and updates, the new authors have retained the core content of the original publication, while bringing an improved focus on new developments and ideas. This edition offers the latest insights in non-linear finite element technology, including non-linear solution strategies, computational plasticity, damage mechanics, time-dependent effects, hyperelasticity and large-strain elasto-plasticity. The authors' integrated and consistent style and unrivalled engineering approach assures this book's unique position within the computational mechanics literature. Key features: Combines the two previous volumes into one heavily revised text with obsolete material removed, an improved layout and updated references and notations Extensive new material on more recent developments in computational mechanics Easily readable, engineering oriented, with no more details in the main text than necessary to understand the concepts. Pseudo-code throughout makes the link between theory and algorithms, and the actual implementation. Accompanied by a website (www.wiley.com/go/deborst) with a Python code, based on the pseudo-code within the book and suitable for solving small-size problems. Non-linear Finite Element Analysis of Solids and Structures, 2nd Edition is an essential reference for practising engineers and researchers that can also be used as a text for undergraduate and graduate students within computational mechanics.

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Breakthroughs in combinatorial chemistry and molecular biology, as well as an overall industry trend toward accelerated development, mean the rate of sample generation now far exceeds the rate of sample analysis in the pursuit of producing new and better pharmaceuticals. LC/MS is an analytical tool that helps the researcher identify the most promising sample early in the selection process, effectively creating a shortcut to finding new drugs. This book is the first to describe LC/MS applications within the context of drug development, including the discovery, preclinical, clinical, and manufacturing phases. In addition to the thorough technical analysis of this tool, LC/MS Applications in Drug Development provides perspective on the significant changes in strategies for pharmaceutical analysis. A process overview of drug development from an analytical point of view is provided along with essential data required to successfully bring a drug to market. The incorporation of LC/MS is illustrated from target to product. Chapters pertaining to the discovery process itself include: Proteomics Glycoprotein Mapping Natural Products Dereplication Lead Identification Screening Open-Access LC/MS In Vitro Drug Screening Written for both the analytical chemist who uses LC/MS applications and the pharmaceutical scientist who works with the drugs they produce, LC/MS Applications in Drug Development is the premier reference on the subject.

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This fascinating selection of over 180 old photographs and postcards depicts Windsor and Eton over the last one hundred years. Windsor's Royal connections and monuments and Eton College are world famous and need no introduction. Perhaps less well known, but no less important, are the streets, people and events of everyday life in and around such internationally renowned landmarks. Street parties, schools, Dr Barnardo's boys, breweries, amateur dramatics, pubs, butchers selling ice cream alongside joints and cuts of meat, evacuees, Boy Scouts, floods, charabanc outings, football teams and the fire brigade are all remembered in this evocative collection. The Thames has always played an important part in the life and development of the town, whether for business or pleasure, as shown by images of boat builders, bridges, steamer trips, the Empress of India, the Windsor Belle and College boys rowing on the river. The author, Mike Stiles, not only spent his formative years in Windsor, but also worked at Windsor Great Park and on many of the buildings in the town. Most of the material in his book has been drawn either from his own extensive collection or from family sources. The result is an informative, affectionate recollection that will appeal to all those who know and love this historic area.

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A look into the growing threats to the popularity of the NFL and what the league can do to avoid collapse The National Football League, despite its massive success and unprecedented earning power, is at its most pivotal moment since the AFL–NFL merger four decades ago. With public awareness of the issues plaguing the NFL—from domestic violence, drug use, and health of the players to oversaturation—there is a possibility that football as we know it could vanish in the very near future. In Two Minute Warning, author Mike Freeman, who has covered the league for almost three decades, looks at all the factors that could cause the league, as we know it, to collapse in on itself. Freeman has interviewed top NFL athletes, coaches, and executives as well as economists and scientists to paint this complete portrait of the league today—and lay out the steps it can take to move into the future.

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Many companies move workloads to the cloud only to encounter issues with legacy processes and organizational structures. How do you design new operating models for this environment? This practical book shows IT managers, CIOs, and CTOs how to address the hardest part of any cloud transformation: the people and the processes. Author Mike Kavis (Architecting the Cloud) explores lessons learned from enterprises in the midst of cloud transformations. You will learn how to rethink your approach from a technology, process, and organizational standpoint to realize the promise of cost optimization, agility, and innovation that public cloud platforms provide. Learn the difference between working in a data center and operating in the cloud Explore patterns and anti-patterns for organizing cloud operating models Get best practices for making the organizational change required for a move to the cloud Understand why site reliability engineering is essential for cloud operations Improve organizational performance through value stream mapping

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