Search results for ""elsevier science technology""

Neurology and Pregnancy provides a comprehensive multidisciplinary guide to best practices for research and practicing neurologists, as well as obstetricians and other specialists caring for women with an acute or chronic neurological disorder. The book encompasses preconception care, genetic counseling, pregnancy in patients with chronic neurological disorders, and acute pregnancy-related neurological complications. Postpartum care and complications, including lactation concerns, are also addressed, as well as the long-term effects of pregnancy and its complications on maternal brain health. Vol 1 summarizes the complex neurophysiological changes in pregnancy from a basic and translational science perspective. This includes neuroimaging, principles of neuro-obstetric critical care, and ethical and medicolegal concerns, describes normal fetal cerebral development and summarizes the management of the most common prenatal neurological diagnoses. Vol 2 focuses on chronic neurological conditions in pregnancy such as epilepsy, migraine, and multiple sclerosis, as well as acute neurological disorders including preeclampsia/ eclampsia, ischemic and hemorrhagic stroke, and CNS infections. Each chapter introduction includes data on epidemiology, when applicable. In discussing management, comments of safety profiles of medications preconceptionally, during pregnancy and lactation are summarized. Each chapter includes 1-2 illustrative cases.

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Neurology and Pregnancy provides a comprehensive multidisciplinary guide to best practices for research and practicing neurologists, as well as obstetricians and other specialists caring for women with an acute or chronic neurological disorder. The book encompasses preconception care, genetic counseling, pregnancy in patients with chronic neurological disorders, and acute pregnancy-related neurological complications. Postpartum care and complications, including lactation concerns, are also addressed, as well as the long-term effects of pregnancy and its complications on maternal brain health. Vol 1 summarizes the complex neurophysiological changes in pregnancy from a basic and translational science perspective. This includes neuroimaging, principles of neuro-obstetric critical care, and ethical and medicolegal concerns, describes normal fetal cerebral development and summarizes the management of the most common prenatal neurological diagnoses. Vol 2 focuses on chronic neurological conditions in pregnancy such as epilepsy, migraine, and multiple sclerosis, as well as acute neurological disorders including preeclampsia/ eclampsia, ischemic and hemorrhagic stroke, and CNS infections. Each chapter introduction includes data on epidemiology, when applicable. In discussing management, comments of safety profiles of medications preconceptionally, during pregnancy and lactation are summarized. Each chapter includes 1-2 illustrative cases.

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Handbook of Commercial Policy explores three main topics that permeate the study of commercial policy. The first section presents a broad set of basic empirical facts regarding the pattern and evolution of commercial policy, with the second section investigating the crosscutting legal issues relating to the purpose and design of agreements. Finally, the third section covers key issues of commercial policy in the modern global economy. Every chapter in the book provides coverage from the perspectives of multilateral, and where appropriate, preferential trade agreements. While most other volumes are policy-oriented, this comprehensive guide explores the ways that intellectual thinking and rigor organize research, further making frontier-level synthesis and current theoretical and empirical research accessible to all.

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What new theories, evidence, explanations, and policies have shaped our studies of income distribution in the 21st century? Editors Tony Atkinson and Francois Bourguignon assemble the expertise of leading authorities in this survey of substantive issues. In two volumes they address subjects that were not covered in Volume 1 (2000), such as education, health and experimental economics; and subjects that were covered but where there have been substantial new developments, such as the historical study of income inequality and globalization. Some chapters discuss future growth areas, such as inheritance, the links between inequality and macro-economics and finance, and the distributional implications of climate change. They also update empirical advances and major changes in the policy environment.

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Principles of Electron Optics: Second Edition, Advanced Wave Optics provides a self-contained, modern account of electron optical phenomena with the Dirac or Schrödinger equation as a starting point. Knowledge of this branch of the subject is essential to understanding electron propagation in electron microscopes, electron holography and coherence. Sections in this new release include, Electron Interactions in Thin Specimens, Digital Image Processing, Acquisition, Sampling and Coding, Enhancement, Linear Restoration, Nonlinear Restoration – the Phase Problem, Three-dimensional Reconstruction, Image Analysis, Instrument Control, Vortex Beams, The Quantum Electron Microscope, and much more.

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Many hereditary cancer syndromes are linked to alterations in single genes. Detection and clinical interpretation of these alterations can guide cancer risk reduction for patients and their families through screening, prophylactic measures, and other strategies. Diagnosis and Management of Hereditary Cancer summarizes hereditary syndromes and their associated cancers and genes. The information is presented in 50 practice-enhancing tables that relate clinical, genetic, diagnostic, and management aspects in a manner that has previously not been available in a single reference. Intended to guide the specialist as well the novice, this volume will elevate the care of hereditary cancer patients and their families.

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There is a growing body of data supporting the usage of cannabis and cannabis-related products in alleviating or preventing symptoms in different diseases and conditions. Medicinal Usage of Cannabis and Cannabinoids offers readers a comprehensive reference on the medical usage and symptom relief provided by these compounds in a variety of disorders. With coverage of neurological diseases like Alzheimer’s and Parkinson’s, and a wide range of other afflictions including depression, anxiety, nausea, and cancer, this broad coverage allows readers to learn about symptom control but also physiological, psychological, and pharmacological effects of these compounds. Unique case reports are provided as well. This volume provides a platform for research on the use of these compounds in improving patient care, brain function, and neurological dysfunction.

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Reproductive and Developmental Toxicology, Third Edition is a comprehensive and authoritative resource, providing the latest literature on this complex subject by focusing on three core components - parent, placenta and fetus - and the continuous changes that occur in each. Enriched with relevant references describing every aspect of reproductive toxicology, this revised and updated resource addresses the totality of the subject, discussing a broad range of topics including nanoparticles and radiation, gases and solvents, smoking, alcohol and drugs of abuse, and metals, among others. In addition, it is the only resource to include reproductive and developmental toxicity in domestic animals, fish and wildlife With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages. Completely revised and updated to include the most recent developments in the field, this book is an essential resource for advanced students and researchers in toxicology, as well as biologists, pharmacologists and teratologists from academia, industry and regulatory agencies.

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MATLAB Programming for Biomedical Engineers and Scientists, Second Edition provides an easy-to-learn introduction to the fundamentals of computer programming in MATLAB. The book explains the principles of good programming practice, while also demonstrating how to write efficient and robust code that analyzes and visualizes biomedical data. Aimed at the biomedical engineering student, biomedical scientist and medical researcher with little or no computer programming experience, this is an excellent resource for learning the principles and practice of computer programming using MATLAB. The book enables the reader to analyze problems and apply structured design methods to produce elegant, efficient and well-structured program designs, implement a structured program design in MATLAB, write code that makes good use of MATLAB programming features, including control structures, functions and advanced data types, and much more.

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Data Mining: Concepts and Techniques, Fourth Edition introduces concepts, principles, and methods for mining patterns, knowledge, and models from various kinds of data for diverse applications. Specifically, it delves into the processes for uncovering patterns and knowledge from massive collections of data, known as knowledge discovery from data, or KDD. It focuses on the feasibility, usefulness, effectiveness, and scalability of data mining techniques for large data sets. After an introduction to the concept of data mining, the authors explain the methods for preprocessing, characterizing, and warehousing data. They then partition the data mining methods into several major tasks, introducing concepts and methods for mining frequent patterns, associations, and correlations for large data sets; data classificcation and model construction; cluster analysis; and outlier detection. Concepts and methods for deep learning are systematically introduced as one chapter. Finally, the book covers the trends, applications, and research frontiers in data mining.

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Computer and Information Security Handbook, Third Edition, provides the most current and complete reference on computer security available in one volume. The book offers deep coverage of an extremely wide range of issues in computer and cybersecurity theory, applications, and best practices, offering the latest insights into established and emerging technologies and advancements. With new parts devoted to such current topics as Cloud Security, Cyber-Physical Security, and Critical Infrastructure Security, the book now has 100 chapters written by leading experts in their fields, as well as 12 updated appendices and an expanded glossary. It continues its successful format of offering problem-solving techniques that use real-life case studies, checklists, hands-on exercises, question and answers, and summaries. Chapters new to this edition include such timely topics as Cyber Warfare, Endpoint Security, Ethical Hacking, Internet of Things Security, Nanoscale Networking and Communications Security, Social Engineering, System Forensics, Wireless Sensor Network Security, Verifying User and Host Identity, Detecting System Intrusions, Insider Threats, Security Certification and Standards Implementation, Metadata Forensics, Hard Drive Imaging, Context-Aware Multi-Factor Authentication, Cloud Security, Protecting Virtual Infrastructure, Penetration Testing, and much more. Online chapters can also be found on the book companion website: https://www.elsevier.com/books-and-journals/book-companion/9780128038437

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Sketching Working Experience: The Workbook provides information about the step-by-step process of the different sketching techniques. It offers methods called design thinking, as a way to think as a user, and sketching, a way to think as a designer. User-experience designers are designers who sketch based on their actions, interactions, and experiences. The book discusses the differences between the normal ways to sketch and sketching used by user-experience designers. It also describes some motivation on why a person should sketch and introduces the sketchbook. The book reviews the different sketching methods and the modules that contain a particular sketching method. It also explains how the sketching methods are used. Readers who are interested in learning, understanding, practicing, and teaching experience design, information design, interface design, and information architecture will find this book relevant.

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Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma: Translational and Clinical Outcomes, Volume Three provides comprehensive information about ongoing research and clinical data on liver cancer. The book presents detailed descriptions about diagnostics and therapeutic options for easy understanding, with a focus on precision medicine approaches to improve treatment outcomes. This updated volume discusses topics such as clinical and safety assessment of HCC patients, liver transplantation as a therapeutic option, immunotherapy interventions, and image-based surveillance. In addition, it discusses immunohistology of HCC-enabled precision medicine and artificial intelligence for hepatocellular carcinomas. This is a valuable resource for cancer researchers, oncologists, graduate students, hepathologists and members of biomedical research who need to understand more about liver cancer to apply in their research work or clinical setting.

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Cell Movement in Health and Disease brings the several scientific domains related to the phenomena together, establishing a consistent foundation for researchers in this exciting field. The content is presented in four main section. The first explores the foundations of Cell Movement, including overviews of cellular structure, signaling, physiology, motion-related proteins, and the interface with the cellular membrane. The second part covers the biological aspects of cellular movement, starting with chemical and mechanical sensing, describing the types of cell movement, mechanics at cell level, cell physiology, collective behavior, and the connections with the extracellular matrix. The following chapters provide an overview of the molecular machinery involved and cell-type specific movement. The third part of the book is dedicated to the translational aspects of cell movement, highlighting the key conditions associated with cell movement dysfunction, like cell invasion in cancer, wound healing, developmental issues, neurological dysfunctions, and immune response. The final part of the book covers key methods and modeling tools for cell movement research, including predictive mathematical models, in vitro and in vivo methods, biophysical and bioinformatics tools. Cell Movement in Health and Disease is the ideal reference for scientists from different backgrounds converging to expand the understanding of this key cellular process. Cellular and molecular biologists will gain a better understanding of the physical principals operating at cellular level while biophysicist and biomedical engineers will benefit from the solid biology foundation provided by the book.

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Stem Cells and COVID-19 presents up-to-date knowledge on the effect of hematopoietic and mesenchymal stem cells to combat SARS-CoV-2 infection in its diagnosis, treatment and prevention. In addition, the book critically discusses challenges, highlighting outstanding questions and future perspectives. Written by global experts in the field for both pre-clinical and clinical practitioners, this comprehensive book delves into how stem cells have a strong potential in developing better diagnostic, treatment and preventive strategies in SARS-CoV-2 infection. Both hematopoietic and mesenchymal stem cells are critical to better understand the response of immune system to coronavirus infection in both healthy and co-morbid conditions in the development of effective vaccines and immunotherapies.

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High-Rise Security and Fire Life Safety, 3e, is a comprehensive reference for managing security and fire life safety operations within high-rise buildings. It spells out the unique characteristics of skyscrapers from a security and fire life safety perspective, details the type of security and life safety systems commonly found in them, outlines how to conduct risk assessments, and explains security policies and procedures designed to protect life and property. Craighead also provides guidelines for managing security and life safety functions, including the development of response plans for building emergencies. This latest edition clearly separates out the different types of skyscrapers, from office buildings to hotels to condominiums to mixed-use buildings, and explains how different patterns of use and types of tenancy impact building security and life safety.

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Unlike books currently on the market, this book attempts to satisfy two goals: combine circuits and electronics into a single, unified treatment, and establish a strong connection with the contemporary world of digital systems. It will introduce a new way of looking not only at the treatment of circuits, but also at the treatment of introductory coursework in engineering in general. Using the concept of ''abstraction,'' the book attempts to form a bridge between the world of physics and the world of large computer systems. In particular, it attempts to unify electrical engineering and computer science as the art of creating and exploiting successive abstractions to manage the complexity of building useful electrical systems. Computer systems are simply one type of electrical systems.

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The fourth edition of Ludwig’s Applied Process Design for Chemical and Petrochemical Plants, Volume Three is a core reference for chemical, plant, and process engineers and provides an unrivalled reference on methods, process fundamentals, and supporting design data. New to this edition are expanded chapters on heat transfer plus additional chapters focused on the design of shell and tube heat exchangers, double pipe heat exchangers and air coolers. Heat tracer requirements for pipelines and heat loss from insulated pipelines are covered in this new edition, along with batch heating and cooling of process fluids, process integration, and industrial reactors. The book also looks at the troubleshooting of process equipment and corrosion and metallurgy.

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When this innovative textbook first appeared in 1984 it rapidly became a great success throughout the world and has already been translated into several European and Asian languages. Now the authors have completely revised and updated the text, including more than 2000 new literature references to work published since the first edition. No page has been left unaltered but the novel features which proved so attractive have been retained. The book presents a balanced, coherent and comprehensive account of the chemistry of the elements for both undergraduate and postgraduate students. This crucial central area of chemistry is full of ingenious experiments, intriguing compounds and exciting new discoveries. The authors specifically avoid the term `inorganic chemistry' since this evokes an outmoded view of chemistry which is no longer appropriate in the final decade of the 20th century. Accordingly, the book covers not only the 'inorganic' chemistry of the elements, but also analytical, theoretical, industrial, organometallic, bio-inorganic and other cognate areas of chemistry. The authors have broken with recent tradition in the teaching of their subject and adopted a new and highly successful approach based on descriptive chemistry. The chemistry of the elements is still discussed within the context of an underlying theoretical framework, giving cohesion and structure to the text, but at all times the chemical facts are emphasized. Students are invited to enter the exciting world of chemical phenomena with a sound knowledge and understanding of the subject, to approach experimentation with an open mind, and to assess observations reliably. This is a book that students will not only value during their formal education, but will keep and refer to throughout their careers as chemists.

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The Cerebellum: Disorders and Treatment, Volume 155 updates readers on the latest and clinically relevant advances in the study of cerebellar diseases in children and adults. It is organized into sections detailing: (1) Disorders (starting from the fetal cerebellum, to adult cerebellum) encountered during daily practice, and (2) Therapy (including insights into innovative drug and rehabilitative approaches). The book's innovative structure discusses cerebellar disorders in children and adults as a continuum, with its companion volume, The Cerebellum: From Embryology to Diagnostic Investigations detailing embryology, anatomy, function and diagnostic investigations and neuroimaging, including conventional sequences, diffusion tensor imaging, functional MRI, and connectivity studies.

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Handbook of Commercial Policy explores three main topics that permeate the study of commercial policy. The first section presents a broad set of basic empirical facts regarding the pattern and evolution of commercial policy, with the second section investigating the crosscutting legal issues relating to the purpose and design of agreements. Final sections cover key issues of commercial policy in the modern global economy. Every chapter in the book provides coverage from the perspectives of multilateral, and where appropriate, preferential trade agreements. While most other volumes are policy-oriented, this comprehensive guide explores the ways that intellectual thinking and rigor organize research, further making frontier-level synthesis and current theoretical, and empirical, research accessible to all.

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Thermoregulation, Part I: From Basic Neuroscience to Clinical Neurology, Volume 154, not only reviews how body temperature regulation changes in neurological diseases, but also how this aspect affects the course and outcomes of each disease. Other sections of the volume review three therapeutic approaches that are aimed at manipulating body temperature, including induced hypothermia, induced hyperthermia and antipyretic therapy. The book is comprised of nine sections across two volumes, five dealing with the basic aspects of body temperature regulation and four dealing with the clinical aspects. Basic sections cover the Thermoregulation system, Thermoreceptors, Thermoeffectors, Neural pathways, and Thermoregulation as a homeostatic function. In addition, the book covers the physiology and neuroanatomy of the thermoregulation system and provides descriptions of how the regulation of body temperature intervenes with other physiological functions (such as sleep, osmoregulation, and immunity), stress, exercise and aging. Basic sections serve as an introduction to the four clinical sections: Body Temperature, Clinical Significance, Abnormal Body Temperature, Thermoregulation in Neurological Disease and Therapeutic Interventions.

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Handbook of the Economics of Population Aging, Volume 1B provides the economic literature on aging and associated subjects, presenting comprehensive portraits of both social and theoretical issues. As the second of two volumes in this series on the economics of population aging, it continues the discussion, delving deeper into topics such as the labor market and human resource issues, gerontology, history, and the sociological and political ramifications of this fascinating topic whose inception dates back to the late 1970’s. This volume includes literature that has appeared in general economics journals, in various field journals in economics, especially, but not exclusively, those covering labor market and human resource issues, information from interdisciplinary social science and life science journals, and data presented in papers by economists published in journals associated with gerontology, history, sociology, political science, and demography, amongst others.

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Handbook of the Economics of Population Aging, Volume 1A, provides the economic literature on aging and associated subjects, including social insurance and healthcare costs. This text explores the economic literature on aging and associated subjects, including social insurance, health care costs, the interests of policymakers, and the role of academics. As the first of two volumes, users will find it a great resource on the topics associated with the economics of aging. Together with its companion, volume 1B, this work includes literature that has appeared in general economics journals, in various field journals in economics, especially, but not exclusively, those covering labor market and human resource issues, information from interdisciplinary social science and life science journals, and data presented in papers by economists published in journals associated with gerontology, history, sociology, political science, and demography, amongst others.

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The Stereotaxic Brain Atlas of the Egyptian Fruit Bat provides the first stereotaxic atlas of the brain of the Egyptian fruit bat (Rousettus aegyptiacus), an emerging model in neuroscience. This atlas contains coronal brain sections stained with cresyl violet (Nissl), AChE, and Parvalbumin – all stereotaxically calibrated. It will serve the needs of any neuroscientist who wishes to work with these bats – allowing to precisely target specific brain areas for electrophysiology, optogenetics, pharmacology, and lesioning. More broadly, this atlas will be useful to all neuroscientists working with bats, as it delineates many brain regions that were not delineated so far in any bat species. Finally, this atlas will provide a useful resource for researchers interested in comparative neuroanatomy of the mammalian brain.

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Project Finance in Theory and Practice: Designing, Structuring, and Financing Private and Public Projects, Fourth Edition provides essential, core coverage of project finance, offering new insights into Sharia-compliant instruments and a comprehensive overview of the current state of international regulation of banking post financial crisis. This updated edition includes new case studies and topics related to country risk, along with insights from project finance experts who share their specialized knowledge on legal issues and the role of advisors in project finance details. The book will be useful for readers at all levels of education and experience who want to learn how to succeed in project finance.

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Practical Data Analytics for Innovation in Medicine: Building Real Predictive and Prescriptive Models in Personalized Healthcare and Medical Research Using AI, ML, and Related Technologies, Second Edition discusses the needs of healthcare and medicine in the 21st century, explaining how data analytics play an important and revolutionary role. With healthcare effectiveness and economics facing growing challenges, there is a rapidly emerging movement to fortify medical treatment and administration by tapping the predictive power of big data, such as predictive analytics, which can bolster patient care, reduce costs, and deliver greater efficiencies across a wide range of operational functions. Sections bring a historical perspective, highlight the importance of using predictive analytics to help solve health crisis such as the COVID-19 pandemic, provide access to practical step-by-step tutorials and case studies online, and use exercises based on real-world examples of successful predictive and prescriptive tools and systems. The final part of the book focuses on specific technical operations related to quality, cost-effective medical and nursing care delivery and administration brought by practical predictive analytics.

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Signal Processing and Machine Learning Theory, authored by world-leading experts, reviews the principles, methods and techniques of essential and advanced signal processing theory. These theories and tools are the driving engines of many current and emerging research topics and technologies, such as machine learning, autonomous vehicles, the internet of things, future wireless communications, medical imaging, etc.

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Histopathology Atlas of Acute Radiation Syndrome and Delayed Effects in Rhesus Macaques: Kidney, Lung, Heart, Intestine and Mesenteric Lymph Node provides a thoroughly illustrated review of the tissue damage and reparative changes associated with standardized irradiation doses in rhesus macaques. In addition to time-sequenced, routinely stained histologic sections, the book presents results of numerous histochemical, immunohistochemical and chromogenic in-situ stains that provide insights into the pathogenesis of radiation-associated tissue injury and repair. This book is compiled and written by a board-certified veterinary pathologist with more than 40 years of experience in the interpretation of experimentally induced tissue alterations in laboratory animals. This is an important resource for researchers in the field of animal science radiation injury, including radiation oncologists and individuals involved in disaster preparedness related to accidental or deliberate radiation exposure in large populations.

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Neurobiology and Physiology of the Endocannabinoid System offers readers a comprehensive reference on the neurobiology of this system and the use of cannabimimetic compounds to induce neurological changes and confer symptom relief. With sections on both natural and synthetic compounds, the book's broad coverage allows readers to learn about their use with multiple conditions, as well as the working biology of the endocannabinoid system, its receptors and its ligands. This volume provides a platform for research on the effects of this system and its modulation in brain function and neurological dysfunction.

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For the first time, in this atlas nuclear physicians and radiologists cover the entire hybrid nuclear medicine (PET/CT, SPECT/CT and PET/MRI), based on their own case studies. The structure in three volumes represents an user friendly guide for interpreting PET and SPECT in relation to co-registered CT and/or MRI. Three companion volumes with a practical structure in two-page unit offer to the reader a navigational tool, based on anatomical districts, with labeled and explained low-dose multiplanar CT or MRI views merged with PET fusion imaging on the right hand and contrast enhanced CT or MRI on the other side. This new format enables rapid identification of hybrid nuclear medicine findings which are now routine at leading medical centers. Volume 1 is focused on brain and neck PET imaging, with emphasis on PET/MRI; Volume 2 concerns thorax, abdomen and pelvis, with particular attention on lung and liver segmental anatomy and evaluation of peritoneum. Special chapters on heart, lymph nodes and musculoskeletal system, are collected in the Volume 3. Each chapter begins with three-dimensional CT and/or MRI views of the evaluated anatomical region, bringing forward sectional tables. Clinical cases, tricks and pitfalls linked to several PET or SPECT radiopharmaceuticals help to introduce the reader to peculiar molecular pathways and to improve confidence in cross-sectional imaging, that is vital for the accurate diagnosis and treatment of diseases.

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Actuarial Principles: Lifetables and Mortality Models explores the core of actuarial science: the study of mortality and other risks and applications. Including the CT4 and CT5 UK courses, but applicable to a global audience, this work lightly covers the mathematical and theoretical background of the subject to focus on real life practice. It offers a brief history of the field, why actuarial notation has become universal, and how theory can be applied to many situations. Uniquely covering both life contingency risks and survival models, the text provides numerous exercises (and their solutions), along with complete self-contained real-world assignments.

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Vitamins and Minerals in Neurological Disorders offers readers a comprehensive reference addressing their relationship to brain health in a wide variety of neurological diseases. Examining various compounds, this broad coverage allows readers to learn about the role nutrient deficiency plays in the pathology of many conditions, as well as their potential in treatment. The book covers diseases including Alzheimer’s, Parkinson’s, ALS, and MS, along with severe neurological conditions like brain injury, stroke, headache and migraine. This volume provides a platform for research on vitamins, minerals and future investigations of these compounds.

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Fault-Tolerant Systems, Second Edition, is the first book on fault tolerance design utilizing a systems approach to both hardware and software. No other text takes this approach or offers the comprehensive and up-to-date treatment that Koren and Krishna provide. The book comprehensively covers the design of fault-tolerant hardware and software, use of fault-tolerance techniques to improve manufacturing yields, and design and analysis of networks. Incorporating case studies that highlight more than ten different computer systems with fault-tolerance techniques implemented in their design, the book includes critical material on methods to protect against threats to encryption subsystems used for security purposes. The text’s updated content will help students and practitioners in electrical and computer engineering and computer science learn how to design reliable computing systems, and how to analyze fault-tolerant computing systems.

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Data Mining: Practical Machine Learning Tools and Techniques, Fourth Edition, offers a thorough grounding in machine learning concepts, along with practical advice on applying these tools and techniques in real-world data mining situations. This highly anticipated fourth edition of the most acclaimed work on data mining and machine learning teaches readers everything they need to know to get going, from preparing inputs, interpreting outputs, evaluating results, to the algorithmic methods at the heart of successful data mining approaches. Extensive updates reflect the technical changes and modernizations that have taken place in the field since the last edition, including substantial new chapters on probabilistic methods and on deep learning. Accompanying the book is a new version of the popular WEKA machine learning software from the University of Waikato. Authors Witten, Frank, Hall, and Pal include today's techniques coupled with the methods at the leading edge of contemporary research. Please visit the book companion website at https://www.cs.waikato.ac.nz/~ml/weka/book.html. It contains Powerpoint slides for Chapters 1-12. This is a very comprehensive teaching resource, with many PPT slides covering each chapter of the book Online Appendix on the Weka workbench; again a very comprehensive learning aid for the open source software that goes with the book Table of contents, highlighting the many new sections in the 4th edition, along with reviews of the 1st edition, errata, etc.

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The new ARM Edition of Computer Organization and Design features a subset of the ARMv8-A architecture, which is used to present the fundamentals of hardware technologies, assembly language, computer arithmetic, pipelining, memory hierarchies, and I/O. With the post-PC era now upon us, Computer Organization and Design moves forward to explore this generational change with examples, exercises, and material highlighting the emergence of mobile computing and the Cloud. Updated content featuring tablet computers, Cloud infrastructure, and the ARM (mobile computing devices) and x86 (cloud computing) architectures is included. An online companion Web site provides links to a free version of the DS-5 Community Edition (a free professional quality tool chain developed by ARM), as well as additional advanced content for further study, appendices, glossary, references, and recommended reading.

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Chemical Engineering Design: SI Edition is one of the best-known and most widely used textbooks available for students of chemical engineering. The enduring hallmarks of this classic book are its scope and practical emphasis which make it particularly popular with instructors and students who appreciate its relevance and clarity. This new edition provides coverage of the latest aspects of process design, operations, safety, loss prevention, equipment selection, and much more, including updates on plant and equipment costs, regulations and technical standards.

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Statistical Mechanics, Fourth Edition, explores the physical properties of matter based on the dynamic behavior of its microscopic constituents. This valuable textbook introduces the reader to the historical context of the subject before delving deeper into chapters about thermodynamics, ensemble theory, simple gases theory, Ideal Bose and Fermi systems, statistical mechanics of interacting systems, phase transitions, and computer simulations. In the latest revision, the book's authors have updated the content throughout, including new coverage on biophysical applications, updated exercises, and computer simulations. This updated edition will be an indispensable to students and researchers of statistical mechanics, thermodynamics, and physics.

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The Bioarchaeology of Metabolic Bone Disease, Second Edition is a comprehensive source dedicated to better understanding this group of conditions that have significant consequences for health in both past and present communities on a global scale. This edition presents an updated introduction to the biology and metabolism of mineralised tissues that are fundamental to understanding the expression of the metabolic bone diseases in skeletal remains. The extensive advances in understanding of these conditions in both bioarchaeological and biomedical work are brought together for the reader. Dedicated chapters focussing on each disease emphasise the integration of up-to-date clinical background with the biological basis of disease progression to give guidance on identification. New chapters covering anaemia and approaches to recognising the co-occurrence of pathological conditions have been included, reflecting recent advances in research. Boxes highlighting significant issues, use of information from sources such as texts and nonhuman primates, and theoretical approaches are included in the text. Each chapter closes with ‘Core Concepts’ that summarise key information. The final chapter reviews current challenges in bioarchaeology and provides directions for future research. This is a must-have resource for users at all career stages interested in integrating information on the metabolic bone diseases into bioarchaeological projects.

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Advances in Aggregation Induced Emission Materials in Biosensing and Imaging for Biomedical Applications - Part B, Volume 185 presents many aspects of AIE materials that can help future investigators, researchers, students and stakeholders perform research with ease. This volume covers various topics, including tissue and protein fibrils imaging by AIE active molecules, theranostic and photodynamic therapy applications of AIE materials for cancer cell treatment, and AIE active polymers and MOF materials for biological applications. Fluorescence-based monitoring and diagnosis platforms furnish extensive insights into the molecular mechanisms of cellular processes, helping us precisely guide therapeutics.

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Contemporary Medical Biotechnology Research for Human Health discusses a range of currently available solutions required to defeat the ever-increasing human health challenges. The junction between biotechnology and biomedical/health sciences has led to several improvements in patients’ treatment, diagnosis and well-being. The book discusses vital topics ranging from biofilms and UTI, mycobacterial infections, diabetes, aplastic anemia, oral cancer, and possible applications of nanoparticles. In addition, it discusses computer-aided drug design using natural products and new technologies to develop antibiotics. This is a valuable resource for biotechnology and biomedical researchers, bioinformaticians and members of health sciences interested in understanding recent technological developments.

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Feedback Control for Personalized Medicine provides ideas on ongoing efforts and obstacles by members of the control engineering community in different biological and medical applications. In addition, the book presents key challenges, insights, tools and theoretical developments that arise from personalized medicine, along with medical concepts that are explained by engineers to help non-experts follow research topics. Several clinical trials have tried to find therapeutic approaches to achieve eradication or at least lifelong, therapy-free, host control of the infection. This has been performed integrating clinical observations, empirical knowledge and information from medical tests to treat patients. As this “trial and error” approach is becoming more challenging and unfeasible by the steep increase in the number of different pieces of information and the complexity of large datasets, a systematic and tractable approach that integrates a variety of biological and medical research data into mathematical models and computational algorithms is crucial to harness knowledge and to develop new therapies towards personalized medicine.

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In an uncertain and complex environment, to ensure secure and stable operations of large-scale power systems is one of the biggest challenges that power engineers have to address today. Traditionally, power system operations and decision-making in controls are based on power system computations of physical models describing the behavior of power systems. Largely, physical models are constructed according to some assumptions and simplifications, and such is the case with power system models. However, the complexity of power system stability problems, along with the system's inherent uncertainties and nonlinearities, can result in models that are impractical or inaccurate. This calls for adaptive or deep-learning algorithms to significantly improve current control schemes that solve decision and control problems. Cyberphysical Infrastructures in Power Systems: Architectures and Vulnerabilities provides an extensive overview of CPS concepts and infrastructures in power systems with a focus on the current state-of-the-art research in this field. Detailed classifications are pursued highlighting existing solutions, problems, and developments in this area.

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The discipline of user experience (UX) design has matured into a confident practice and this edition reflects, and in some areas accelerates, that evolution. Technically this is the second edition of The UX Book, but so much of it is new, it is more like a sequel. One of the major positive trends in UX is the continued emphasis on design—a kind of design that highlights the designer’s creative skills and insights and embodies a synthesis of technology with usability, usefulness, aesthetics, and meaningfulness to the user. In this edition a new conceptual top-down design framework is introduced to help readers with this evolution. This entire edition is oriented toward an agile UX lifecycle process, explained in the funnel model of agile UX, as a better match to the now de facto standard agile approach to software engineering. To reflect these trends, even the subtitle of the book is changed to “Agile UX design for a quality user experience”. Designed as a how-to-do-it handbook and field guide for UX professionals and a textbook for aspiring students, the book is accompanied by in-class exercises and team projects. The approach is practical rather than formal or theoretical. The primary goal is still to imbue an understanding of what a good user experience is and how to achieve it. To better serve this, processes, methods, and techniques are introduced early to establish process-related concepts as context for discussion in later chapters.

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