Search results for ""author ji-qian fang""

This textbook consists of three parts: basic concepts of statistics, advanced statistical methods, and design and analysis for medical research. Each chapter begins with challenging medical problems and related statistical methods and theories; to make the statistical ideas more easily understood, there is a section of “computer experiments” in each chapter where some basic statistical phenomena and related concepts are revealed. The statistical software SAS is used to carry out related statistical calculations.The aim of this book is to make medical students and researchers grasp easily the most useful tools of statistics for their medical research. It is done through various applications to a great number of medical problems, interesting demonstration of well-designed computer experiments and detailed explanation of statistical thinking.

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The book aims to provide both comprehensive reviews of the classical methods and an introduction to new developments in medical statistics. The topics range from meta analysis, clinical trial design, causal inference, personalized medicine to machine learning and next generation sequence analysis. Since the publication of the first edition, there have been tremendous advances in biostatistics and bioinformatics. The new edition tries to cover as many important emerging areas and reflect as much progress as possible. Many distinguished scholars, who greatly advanced their research areas in statistical methodology as well as practical applications, also have revised several chapters with relevant updates and written new ones from scratch.The new edition has been divided into four sections, including, Statistical Methods in Medicine and Epidemiology, Statistical Methods in Clinical Trials, Statistical Genetics, and General Methods. To reflect the rise of modern statistical genetics as one of the most fertile research areas since the publication of the first edition, the brand new section on Statistical Genetics includes entirely new chapters reflecting the state of the art in the field.Although tightly related, all the book chapters are self-contained and can be read independently. The book chapters intend to provide a convenient launch pad for readers interested in learning a specific topic, applying the related statistical methods in their scientific research and seeking the newest references for in-depth research.

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