Search results for ""Author Carsten Wiuf""
Oxford University Press Statistics and Informatics in Molecular Cancer Research
Molecular understanding of cancer and cancer progression is at the forefront of many research programs today. High-throughput array technologies and other modern molecular techniques produce a wealth of molecular data about the structure, and function of cells, tissues, and organisms. Correctly analyzed and interpreted these data hold the promise of bringing new markers for prognostic and diagnostic use, for new treatment schemes, and of gaining new biological insight into the evolution of cancer and its molecular, pathological, and clinical consequences. Aimed at graduates and researchers, this book discusses novel advances in informatics and statistics in molecular cancer research. Through eight chapters from carefully chosen experts it brings the reader up to date with specific topics in cancer research, how the topics give rise to development of new informatics and statistics tools, and how the tools can be applied. The focus of the book is to give the reader an understanding of key concepts and tools, rather than focusing on technical issues. A main theme is the extensive use of array technologies in modern cancer research - gene expression and exon arrays, SNP and copy number arrays, and methylation arrays - to derive quantitative and qualitative statements about cancer, its progression and aetiology, and to understand how these technologies on one hand allow us learn about cancer tissue as a complex system and on the other hand allow us to pinpoint key genes and events as crucial for the development of the disease.
£78.30
Imperial College Press Statistical And Evolutionary Analysis Of Biological Networks
Networks provide a very useful way to describe a wide range of different data types in biology, physics and elsewhere. Apart from providing a convenient tool to visualize highly dependent data, networks allow stringent mathematical and statistical analysis.In recent years, much progress has been achieved to interpret various types of biological network data such as transcriptomic, metabolomic and protein interaction data as well as epidemiological data. Of particular interest is to understand the organization, complexity and dynamics of biological networks and how these are influenced by network evolution and functionality.This book reviews and explores statistical, mathematical and evolutionary theory and tools in the understanding of biological networks. The book is divided into comprehensive and self-contained chapters, each of which focuses on an important biological network type, explains concepts and theory and illustrates how these can be used to obtain insight into biologically relevant processes and questions. There are chapters covering metabolic, transcriptomic, protein interaction and epidemiological networks as well as chapters that deal with theoretical and conceptual material. The authors, who contribute to the book, are active, highly regarded and well-known in the network community.
£81.00
