Search results for ""Author Wolf""

Der Arzneiverordnungs-Report ist seit 1985 eine gemeinsame Publikation von Autoren aus Pharmakologie, Klinik, Praxis, Gesundheitsökonomie und Krankenversicherung. Basis sind die Verordnungsdaten von Arzneimitteln für ambulante Patienten der gesetzlichen Krankenversicherung (GKV). Datenbasis des Jahres 2020 sind ca. 820 Mio. Verordnungen von 150.363 Vertragsärzten und 62.876 Vertragszahnärzten für 73,4 Mio. GKV-Versicherte. Die allgemeine Verordnungs- und Marktentwicklung wird in 6 Kapiteln behandelt, in denen u.a. neue Arzneimittel des Jahres 2020, die Kosten-Nutzen-Analyse von onkologischen Arzneimitteln, Marktsteuerungsmechanismen und Preise von Biologika bzw. Biosimilars sowie die Klassifizierung von Arzneistoffgruppen diskutiert werden.Die Nettokosten für Arzneimittel in der GKV sind 2020 weiter um 5 % auf rund 46 Mrd. € gestiegen, vor allem durch neue, hochpreisige Patentarzneimittel. Hauptkostentreiber waren Onkologika (9,5 Mrd. €, + 12,4 %) und Antidiabetika (2,8 Mrd. €, + 16,8 %). Ein wesentlicher Grund für die Kostenprobleme ist der seit Jahren beobachtete Anstieg der Jahrestherapiekosten neu eingeführter Arzneimittel. Dieser Trend zu hochpreisigen Patentarzneimitteln ist durch das Arzneimittelmarktneuordnungsgesetz (AMNOG) sogar 10 Jahre nach seiner Einführung nicht genügend abgeschwächt worden, auch wenn mit der Vereinbarung von Erstattungsbeträgen 2020 insgesamt 3,7 Mrd. € an Einsparungen erzielt werden konnten.

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Im seit 1985 jährlich als Buch erscheinenden Arzneiverordnungs-Report werden die Rezepte für die Patienten der gesetzlichen Krankenversicherung (GKV) mit Methoden der evidenzbasierten Medizin analysiert.Seit dieser Zeit bietet der Report eine unabhängige Informationsmöglichkeit über die verschiedenen Komponenten der Arzneimittelverordnung und trägt damit zur Transparenz des Arzneimittelmarkts, zur Bewertung von Arzneimitteln und zu einer sowohl zweckmäßigen und sicheren evidenzbasierten als auch wirtschaftlichen Arzneitherapie bei.

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Built and designed by Ludwig Mies van der Rohe 1928–1930, the Tugendhat House in Brno / Czech Republic is one of the most significant buildings of European modernism. In 2001, UNESCO added the house to the List of World Cultural Heritage Sites. In this third, updated edition, the authors give personal and historic insights relating to the house; also documenting aspects pertaining to art history and conservation-science studies. The comprehensive description and in-depth discussion of the materials used is a special feature in this field of research. The appeal of this monograph lies in the publication of photographs from the family archive which, for the first time, show the house in its lived-in condition. The experimental artistic color photographs by Fritz Tugendhat are among the pioneering achievements of amateur photography.

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This second, completely updated edition of a classic textbook provides a concise introduction to the fundamental principles of modern electrochemistry, with an emphasis on applications in energy technology. The renowned and experienced scientist authors present the material in a didactically skilful and lucid manner. They cover the physical-chemical fundamentals as well as such modern methods of investigation as spectroelectrochemistry and mass spectrometry, electrochemical analysis and production methods, as well as fuel cells and micro- and nanotechnology. The result is a must-have for advanced chemistry students as well as those studying chemical engineering, materials science and physics.

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The demands of producing high quality, pathogen-free food rely increasingly on natural sources of antimicrobials to inhibit food spoilage organisms, foodborne pathogens and toxins. Discovery and development of new antimicrobials from natural sources for a wide range of applications requires that knowledge of traditional sources for food antimicrobials is combined with the latest technologies in identification, characterization and application. This book explores some novel, natural sources of antimicrobials as well as the latest developments in using well-known antimicrobials in food. Covering antimicrobials derived from microbial sources (bacteriophages, bacteria, algae, fungi), animal-derived products (milk proteins, chitosan, reduction of biogenic amines), plants and plant-products (essential oils, phytochemicals, bioactive compounds), this book includes the development and use of natural antimicrobials for processed and fresh food products. New and emerging technologies concerning antimicrobials are also discussed.

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Kompakt, interdiziplinär, praxisorientiert - so präsentiert sich dieses facettenreiche Lehrbuch der Photochemie. Das gut strukturierte und sehr verstandlich geschriebene Werk macht den Leser mit allen bedeutenden photochemischen Prozessen vertraut.

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The volume traces back to a symposium held at the Max Planck Institute for Comparative and International Private Law in Hamburg and offers a broad comparative analysis of company and capital markets law in Germany and the Nordic states. It details the special elements of company law in Scandinavia that developed amid the twin forces of innovative experimentation and the drive for harmonization, contrasting them with the distinctive features of German company law. Further contributions deal with the newly created entrepreneur company in Germany and Denmark, as well as the role of shareholders and boards in public companies. It also contains detailed analyses of the law of company groups in Germany and the Nordic states. the volume is further rounded out with contributions on capital markets law and takeover law, including issues involving acting in concert, ownership disclosure and the interaction between the legislator and the takeover panel in Sweden.

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Oils and fats are almost ubiquitous in food processing, whether naturally occurring in foods or added as ingredients that bring functional benefits. Whilst levels of fat intake must be controlled in order to avoid obesity and other health problems, it remains the fact that fats (along with proteins and carbohydrates) are one of the three macronutrients and therefore an essential part of a healthy diet. The ability to process oils and fats to make them acceptable as part of our food supplies is a key component in our overall knowledge of them. Without this ability, the food that we consume would be totally different, and much of the flexibility available to us as a result of the application of processing techniques would be lost. Obviously we need to know how to process fatty oils, but we also need to know how best to use them once they have been processed. This second edition of Edible Oil Processing presents a valuable overview of the technology and applications behind the subject. It covers the latest technologies which address new environmental and nutritional requirements as well as the current state of world edible oil markets. This book is intended for food scientists and technologists who use oils and fats in food formulations, as well as chemists and technologists working in edible oils and fats processing.

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A concise, updated guide to the 3GPP LTE Security Standardization specifications A welcome Revised Edition of the successful LTE Security addressing the security architecture for SAE/LTE, which is based on elements of the security architectures for GSM and 3G, but which needed a major redesign due to the significantly increased complexity, and different architectural and business requirements of fourth generation systems. The authors explain in detail the security mechanisms employed to meet these requirements. The specifications generated by standardization bodies only inform about how to implement the system (and this only to the extent required for interoperability), but almost never inform readers about why things are done the way they are. Furthermore, specifications tend to be readable only for a small group of experts and lack the context of the broader picture. The book fills this gap by providing first hand information from insiders who participated in decisively shaping SAE/LTE security in the relevant standardization body, 3GPP, and can therefore explain the rationale for design decisions in this area. A concise, fully updated guide to the 3GPP LTE Security Standardization specifications Describes the essential elements of LTE and SAE Security, written by leading experts who participated in decisively shaping SAE/LTE security in the relevant standardization body, 3GPP Explains the rationale behind the standards specifications giving readers a broader understanding of the context to these specifications Includes new chapters covering 3GPP work on system enhancements for MTC, plus application layer security in ETSI TC M2M and embedded smart card in ETSI SCP; Security for Machine-type Communication, Relay Node Security, and Future Challenges, including Voice over LTE, MTC, Home base stations, LIPA/SIPTO, and New Cryptographic Algorithms Essential reading for System engineers, developers and people in technical sales working in the area of LTE and LTE security, communication engineers and software developers in mobile communication field.

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Architecture and freehand drawing are inextricably linked. Even in the Gothic period, the principle applied: what you can't build, you at least draw. The same applies to the sketches of Wolf dPrix, co-founder and CEO of Coop Himmelb(l)au. Over the 53 years of their creation, Prix’s sketches formed the first stage of every design – despite rapid developments in digital architecture. Whereas his freehand drawings were proxies for completed projects in the 1960s and 1970s, today they serve as strategic guides to the firm’s complex buildings. From 2,800 archival drawings, 1,300 examples were selected for publication to represent developmental dynamics in an archive-like format. As invaluable documents of architectural history, they illustrate some 320 selected projects.

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Every week the TV news highlights the routine use of drones and guided missiles against terrorist enemies and the recreational use of drones has become commonplace. The Nazi WWII development of guided missiles and bombs is often given credit for America's Cold War success in this realm. However, it was during that war that America, and the Air Force, in particular, also began the development of systems and weapons that laid the foundation for today's technology. 'Off Target' relates in detail the then "Secret" research, development, and combat employment of these early guided bombs, missiles, and drones from 1917 to 1948. Using formerly Secret/Confidential manuals, reports, microfilm print outs, and photos, collected over 40 years, author Wolf, gives the air war historian and enthusiast a detailed look at this unknown topic that progressed from biplane drones to sophisticated post-WWII guided missiles. Among the subjects discussed are Sperry's aerial torpedo and the Kettering "Bug" of WWI to WWII's early rudimentary GB Series Glide Bombs to the more sophisticated VB Series that evolved from radio, heat, light, or television guidance. The Aphrodite/Joseph Kennedy B-17, BQ, TDR, and target drones are discussed as are the SWOD, GLOMB, GORGON, and JB Jet bomb series.

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