Search results for ""Elsevier Science""

Feedback Control for Personalized Medicine provides ideas on ongoing efforts and obstacles by members of the control engineering community in different biological and medical applications. In addition, the book presents key challenges, insights, tools and theoretical developments that arise from personalized medicine, along with medical concepts that are explained by engineers to help non-experts follow research topics. Several clinical trials have tried to find therapeutic approaches to achieve eradication or at least lifelong, therapy-free, host control of the infection. This has been performed integrating clinical observations, empirical knowledge and information from medical tests to treat patients. As this “trial and error” approach is becoming more challenging and unfeasible by the steep increase in the number of different pieces of information and the complexity of large datasets, a systematic and tractable approach that integrates a variety of biological and medical research data into mathematical models and computational algorithms is crucial to harness knowledge and to develop new therapies towards personalized medicine.

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In an uncertain and complex environment, to ensure secure and stable operations of large-scale power systems is one of the biggest challenges that power engineers have to address today. Traditionally, power system operations and decision-making in controls are based on power system computations of physical models describing the behavior of power systems. Largely, physical models are constructed according to some assumptions and simplifications, and such is the case with power system models. However, the complexity of power system stability problems, along with the system's inherent uncertainties and nonlinearities, can result in models that are impractical or inaccurate. This calls for adaptive or deep-learning algorithms to significantly improve current control schemes that solve decision and control problems. Cyberphysical Infrastructures in Power Systems: Architectures and Vulnerabilities provides an extensive overview of CPS concepts and infrastructures in power systems with a focus on the current state-of-the-art research in this field. Detailed classifications are pursued highlighting existing solutions, problems, and developments in this area.

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The discipline of user experience (UX) design has matured into a confident practice and this edition reflects, and in some areas accelerates, that evolution. Technically this is the second edition of The UX Book, but so much of it is new, it is more like a sequel. One of the major positive trends in UX is the continued emphasis on design—a kind of design that highlights the designer’s creative skills and insights and embodies a synthesis of technology with usability, usefulness, aesthetics, and meaningfulness to the user. In this edition a new conceptual top-down design framework is introduced to help readers with this evolution. This entire edition is oriented toward an agile UX lifecycle process, explained in the funnel model of agile UX, as a better match to the now de facto standard agile approach to software engineering. To reflect these trends, even the subtitle of the book is changed to “Agile UX design for a quality user experience”. Designed as a how-to-do-it handbook and field guide for UX professionals and a textbook for aspiring students, the book is accompanied by in-class exercises and team projects. The approach is practical rather than formal or theoretical. The primary goal is still to imbue an understanding of what a good user experience is and how to achieve it. To better serve this, processes, methods, and techniques are introduced early to establish process-related concepts as context for discussion in later chapters.

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Investment Banks, Hedge Funds, and Private Equity, Fourth Edition provides a real-world view of this fast-evolving field, reviewing and analyzing recent innovations and developments. This reference captures the actual work of bankers and professional investors, providing readers with templates for real transactions and insight on how investment banks, hedge funds, and private equity firms provide services to each other while creating opportunities for corporations and investors to raise capital, invest, hedge, finance, acquire, divest, and risk manage. For each type of institution, the business model, organizational structure, products, challenges, regulatory issues, and profit-making opportunities are explained. In addition, specific transactions are analyzed to make clear how advisory services, financings, investments, and trades produce profits or losses, and which types of risks are most commonly taken by each type of institution. Importantly, the linkage of investment banks, hedge funds, and private equity to corporations, governments, and individuals is described, enabling the reader to more clearly understand how these organizations impact them and how their products and services can be best utilized.

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User interface (UI) design rules and guidelines, developed by early HCI gurus and recognized throughout the field, were based on cognitive psychology (study of mental processes such as problem solving, memory, and language), and early practitioners were well informed of its tenets. But today practitioners with backgrounds in cognitive psychology are a minority, as user interface designers and developers enter the field from a wide array of disciplines. HCI practitioners today have enough experience in UI design that they have been exposed to UI design rules, but it is essential that they understand the psychological basis behind the rules in order to effectively apply them. In Designing with the Mind in Mind, best-selling author Jeff Johnson provides designers with just enough background in perceptual and cognitive psychology that UI design guidelines make intuitive sense rather than being just a list of rules to follow.

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Physically Based Rendering: From Theory to Implementation, Third Edition, describes both the mathematical theory behind a modern photorealistic rendering system and its practical implementation. Through a method known as 'literate programming', the authors combine human-readable documentation and source code into a single reference that is specifically designed to aid comprehension. The result is a stunning achievement in graphics education. Through the ideas and software in this book, users will learn to design and employ a fully-featured rendering system for creating stunning imagery. This completely updated and revised edition includes new coverage on ray-tracing hair and curves primitives, numerical precision issues with ray tracing, LBVHs, realistic camera models, the measurement equation, and much more. It is a must-have, full color resource on physically-based rendering.

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The new generation of 32-bit PIC microcontrollers can be used to solve the increasingly complex embedded system design challenges faced by engineers today. This book teaches the basics of 32-bit C programming, including an introduction to the PIC 32-bit C compiler. It includes a full description of the architecture of 32-bit PICs and their applications, along with coverage of the relevant development and debugging tools. Through a series of fully realized example projects, Dogan Ibrahim demonstrates how engineers can harness the power of this new technology to optimize their embedded designs. With this book you will learn: The advantages of 32-bit PICs The basics of 32-bit PIC programming The detail of the architecture of 32-bit PICs How to interpret the Microchip data sheets and draw out their key points How to use the built-in peripheral interface devices, including SD cards, CAN and USB interfacing How to use 32-bit debugging tools such as the ICD3 in-circuit debugger, mikroCD in-circuit debugger, and Real Ice emulator

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Sports Neurology is designed to be a comprehensive overview of neurology within the context of sports medicine. This definitive text addresses the history of sports neurology, including its unique role within sports medicine, and provides a detailed assessment of central and peripheral nervous system injuries and illnesses in athletes. Sports Neurology is a critical companion for all sports medicine clinicians and for neurologists who manage athletes.

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Athymic Nude Rat Brain Atlas will provide the first stereotaxic brain atlas of the athymic nude rat (Crl:NIH-Foxn1rnu), a T-cell deficient rat model commonly used in experimental studies and pre-clinical safety and efficacy studies. This 2D vector-based atlas contains coronal, sagittal, and horizontal brain sections of an athymic rat brain rendered from a single cleared specimen, placed in a computerized 3D environment. The maps enable readers to better calculate co-ordinates to target specific structures for toxin, virus, or cell delivery using stereotaxic surgery. This atlas will be a valuable resource for any neuroscientist who wishes to work with nude rats in experimental and pre-clinical studies.

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Introduction to Business Analytics Using Simulation, Second Edition employs an innovative strategy to teach business analytics. The book uses simulation modeling and analysis as mechanisms to introduce and link predictive and prescriptive modeling. Because managers can't fully assess what will happen in the future, but must still make decisions, the book treats uncertainty as an essential element in decision-making. Its use of simulation gives readers a superior way of analyzing past data, understanding an uncertain future, and optimizing results to select the best decision. With its focus on uncertainty and variability, this book provides a comprehensive foundation for business analytics. Students will gain a better understanding of fundamental statistical concepts that are essential to marketing research, Six-Sigma, financial analysis, and business analytics.

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MRI/DTI Atlas of the Human Brainstem in Transverse and Sagittal Planes presents a detailed view of the human brainstem in DTI/MRI. It is the first ever MRI or histological atlas to present detailed diagrams of sagittal views of the brainstem. Presenting data of unprecedented quality, images are juxtaposed with detailed diagrams in the transverse and sagittal planes. The atlas features a 50 micron resolution for the GRE and 200 microns for the FAC and DWI, 8000 times higher than that seen in a clinical MRI and 1000 times higher than that seen in a clinical DTI scan, all based on one brain. This atlas is important for neuroscientists, neurosurgeons, pathologists, anatomists, neurophysiologists, radiologists, radiotherapists (e.g., for cyberknife guidance), and graduate students in neuroscience.

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A key to being confident in the evaluation of skeletal trauma imaging is to rely on the identification of mechanism-specific traumatic features. Indeed, for each mechanism of injury applied to a particular part of the skeleton, the latter can only present predefined traumatic injuries: this is a pattern of injuries.The recognition of such a pattern of imaging allows the reader to determine the injuring mechanism and look for damages of lesser expression (or even invisible damages) that are common to the identified mechanism. In becoming more familiar with those mechanisms, the readers can deal with trauma imaging more efficiently and directly focus on findings relevant for further management.Skeletal Trauma: A Mechanism-Based Approach of Imaging aims to combine the knowledge of both radiologists and surgeons to propose a mechanism-based approach to imaging in skeletal trauma. Along 15 chapters covering every part of the skeleton, with more than 900 figures, this book reviews the anatomy, standard radiologic views, and imaging findings of skeletal trauma. Over 200 original schemas invite the reader to understand the imaging features and determine the injuring mechanism.

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Pipeline Rules of Thumb Handbook: A Manual of Quick, Accurate Solutions to Everyday Pipeline Engineering Problems, Ninth Edition, the latest release in the series, serves as the "go-to" source for all pipeline engineering answers. Updated with new data, graphs and chapters devoted to economics and the environment, this new edition delivers on new topics, including emissions, decommissioning, cost curves, and more while still maintaining the quick answer standard display of content and data that engineers have utilized throughout their careers. Glossaries are added per chapter for better learning tactics, along with additional storage tank and LNG fundamentals. This book continues to be the high-quality, classic reference to help pipeline engineers solve their day-to-day problems.

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Computer Organization and Design: The Hardware/Software Interface, Sixth Edition, the leading, award-winning textbook from Patterson and Hennessy used by more than 40,000 students per year, continues to present the most comprehensive and readable introduction to this core computer science topic. Improvements to this new release include new sections in each chapter on Domain Specific Architectures (DSA) and updates on all real-world examples that keep it fresh and relevant for a new generation of students.

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Network Algorithmics: An Interdisciplinary Approach to Designing Fast Networked Devices, Second Edition takes an interdisciplinary approach to applying principles for efficient implementation of network devices, offering solutions to the problem of network implementation bottlenecks. In designing a network device, there are dozens of decisions that affect the speed with which it will perform – sometimes for better, but sometimes for worse. The book provides a complete and coherent methodology for maximizing speed while meeting network design goals. The book is uniquely focused on the seamless integration of data structures, algorithms, operating systems and hardware/software co-designs for high-performance routers/switches and network end systems. Thoroughly updated based on courses taught by the authors over the past decade, the book lays out the bottlenecks most often encountered at four disparate levels of implementation: protocol, OS, hardware and architecture. It then develops fifteen principles key to breaking these bottlenecks, systematically applying them to bottlenecks found in end-nodes, interconnect devices and specialty functions located along the network. Later sections discuss the inherent challenges of modern cloud computing and data center networking.

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Advances in GPU Research and Practice focuses on research and practices in GPU based systems. The topics treated cover a range of issues, ranging from hardware and architectural issues, to high level issues, such as application systems, parallel programming, middleware, and power and energy issues. Divided into six parts, this edited volume provides the latest research on GPU computing. Part I: Architectural Solutions focuses on the architectural topics that improve on performance of GPUs, Part II: System Software discusses OS, compilers, libraries, programming environment, languages, and paradigms that are proposed and analyzed to help and support GPU programmers. Part III: Power and Reliability Issues covers different aspects of energy, power, and reliability concerns in GPUs. Part IV: Performance Analysis illustrates mathematical and analytical techniques to predict different performance metrics in GPUs. Part V: Algorithms presents how to design efficient algorithms and analyze their complexity for GPUs. Part VI: Applications and Related Topics provides use cases and examples of how GPUs are used across many sectors.

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The Art of Multiprocessor Programming, Second Edition, provides users with an authoritative guide to multicore programming. This updated edition introduces higher level software development skills relative to those needed for efficient single-core programming, and includes comprehensive coverage of the new principles, algorithms, and tools necessary for effective multiprocessor programming. The book is an ideal resource for students and professionals alike who will benefit from its thorough coverage of key multiprocessor programming issues.

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Non-equilibrium States and Glass Transitions in Foods: Processing Effects and Product Specific Implications presents the tactics needed to understand and control non-equilibrium states and glass transitions in food, an essential element in maintaining the shelf-life and quality of foods. After brief introductory chapters introduce the science behind non-equilibrium states and glass transitions in foods, the book details how glass transition temperature is affected by composition and the ways it influences processability and physico-chemical changes during the storage of foods, also exploring how these effects can be controlled. The second section looks at individual foods, highlighting the implications of non-equilibrium states and glass transitions within these foods. Maintaining and improving the quality of food is of upmost importance to food companies who have to ensure that the shelf life of their products is as long as possible. A large amount of research has been performed into glass transitions in food over the last few years, however there has not been a comprehensive review. This book fills that gap.

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Immunotherapeutics, Volume 129 in the Advances in Protein Chemistry and Structural Biology series highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Vaccines for the prophylaxis and treatment of HPV, Lung-targeted RNA-based therapeutics, Clostridium difficile: Current overview and future perspectives, Antivenoms for treatment of snake bites, Natural killer cell-based strategies for immunotherapy of cancer, Immunological insights of selectins in human disease mechanism, Current update, challenges, and future aspects of immunotherapeutics in non-small cell lung cancer, In silico interaction analysis of NEMO binding domain peptide on the NFkB protein, and much more.

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Prehospital Transport and Whole-body Vibration helps medical transport professionals and vehicle and equipment designers understand the concepts of human response to whole body vibration in order to shed light on the ongoing debate on the effectiveness of current immobilization systems. Written for anyone working with patients who have been medically transported, such as emergency medicine physicians, medics, ER nurses, and those researching and studying whole-body vibration (medical students, ergonomists, human factor researchers, engineers, system developers), this book takes an informative look at situations that occur in the air, on the sea and in ground medical vehicles en route to a hospital. The transport of supine humans under these conditions may lead to severe involuntary motions of body segments, which can generate discomfort, pain and secondary injuries, especially when the patient has a suspected spinal cord injury. This book will help medical transport professionals and vehicle and equipment designers understand the basic concepts of human response to whole body vibration and shed light on the ongoing debate on the effectiveness of current immobilization systems.

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Essential MATLAB for Engineers and Scientists, Eighth Edition provides a concise and balanced overview of MATLAB's functionality, covering both fundamentals and applications. The essentials are illustrated throughout, featuring complete coverage of the software's windows and menus. Program design and algorithm development are presented, along with many examples from a wide range of familiar scientific and engineering areas. This edition has been updated to include the latest MATLAB versions through 2021a. This is an ideal book for a first course on MATLAB, but is also ideal for an engineering problem-solving course using MATLAB.

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Comparative Veterinary Anatomy: A Clinical Approach describes the comprehensive, clinical application of anatomy for veterinarians, veterinary students, allied health professionals and undergraduate students majoring in biology and zoology. The book covers the applied anatomy of dogs, cats, horses, cows and other farm animals, with a short section on avian/exotics, with a focus on specific clinical anatomical topics. The work improves the understanding of basic veterinary anatomy by making it relevant in the context of common clinical problems. This book will serve as a single-source reference on the application of important anatomical structures in a clinical setting. Students, practitioners and specialists will find this information easy-to-use and well-illustrated, thus presenting an accurate representation of essential anatomical structures that relates to real-life clinical situations in veterinary medicine.

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Mental illness and the variety of conditions, disorders, and phobias associated with it impact not only the individual but also the family unit, the community, and society at large. Handbook of Cognitive Behavioral Therapy by Disorder: Case Studies and Application for Adults will better readers’ understanding of a variety of these conditions in adults specifically and the applicability of CBT therapy as a treatment. Featuring chapters on schizophrenia, bipolar disorder, dysmorphia, depression, and anxiety, the book discusses in detail the use of cognitive behavioral therapies in the treatment of these issues in adults. With expert authors from the clinical field, the book has applicability for behavioral scientists, psychologists, cognitive and behavioral neuroscientists, and anyone working to better understand and treat using cognitive behavioral therapies.

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Computer Organization and Design RISC-V Edition: The Hardware Software Interface, Second Edition, the award-winning textbook from Patterson and Hennessy that is used by more than 40,000 students per year, continues to present the most comprehensive and readable introduction to this core computer science topic. This version of the book features the RISC-V open source instruction set architecture, the first open source architecture designed for use in modern computing environments such as cloud computing, mobile devices, and other embedded systems. Readers will enjoy an online companion website that provides advanced content for further study, appendices, glossary, references, links to software tools, and more.

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Presenting the best practices of the best manufacturing companies in the world, this book presents proven models for achieving world-class performance. Using a case study of a fictional company called Beta International, Moore illustrates how to increase uptime, lower costs, increase market share, maximize asset utilization, apply benchmarks and best practices, and improve many other aspects that ultimately raise your company's performance to the level of world-class. "Making Common Sense Common Practice" takes a good, hard look at plant design, procurement, parts management, installation and maintenance, training, and implementing a computerized maintenance management system. In discussing the successes and failures of the world's premier manufacturers, Moore outlines a stable path of growth for almost any manufacturing company. In today's tough competitive markets, "Making Common Sense Common Practice" greatly enhances your company's chance to succeed - and profit. The third edition features updating plus new sections on innovation, change management, and leadership. It presents proven models for achieving world-class performance based on real-life case histories. The highly readable, concrete style brings the key points to life through a case study of a fictitious organization, Beta International, which runs throughout the book, based on real case histories.

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Neurology and Pregnancy provides a comprehensive multidisciplinary guide to best practices for research and practicing neurologists, as well as obstetricians and other specialists caring for women with an acute or chronic neurological disorder. The book encompasses preconception care, genetic counseling, pregnancy in patients with chronic neurological disorders, and acute pregnancy-related neurological complications. Postpartum care and complications, including lactation concerns, are also addressed, as well as the long-term effects of pregnancy and its complications on maternal brain health. Vol 1 summarizes the complex neurophysiological changes in pregnancy from a basic and translational science perspective. This includes neuroimaging, principles of neuro-obstetric critical care, and ethical and medicolegal concerns, describes normal fetal cerebral development and summarizes the management of the most common prenatal neurological diagnoses. Vol 2 focuses on chronic neurological conditions in pregnancy such as epilepsy, migraine, and multiple sclerosis, as well as acute neurological disorders including preeclampsia/ eclampsia, ischemic and hemorrhagic stroke, and CNS infections. Each chapter introduction includes data on epidemiology, when applicable. In discussing management, comments of safety profiles of medications preconceptionally, during pregnancy and lactation are summarized. Each chapter includes 1-2 illustrative cases.

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Neurology and Pregnancy provides a comprehensive multidisciplinary guide to best practices for research and practicing neurologists, as well as obstetricians and other specialists caring for women with an acute or chronic neurological disorder. The book encompasses preconception care, genetic counseling, pregnancy in patients with chronic neurological disorders, and acute pregnancy-related neurological complications. Postpartum care and complications, including lactation concerns, are also addressed, as well as the long-term effects of pregnancy and its complications on maternal brain health. Vol 1 summarizes the complex neurophysiological changes in pregnancy from a basic and translational science perspective. This includes neuroimaging, principles of neuro-obstetric critical care, and ethical and medicolegal concerns, describes normal fetal cerebral development and summarizes the management of the most common prenatal neurological diagnoses. Vol 2 focuses on chronic neurological conditions in pregnancy such as epilepsy, migraine, and multiple sclerosis, as well as acute neurological disorders including preeclampsia/ eclampsia, ischemic and hemorrhagic stroke, and CNS infections. Each chapter introduction includes data on epidemiology, when applicable. In discussing management, comments of safety profiles of medications preconceptionally, during pregnancy and lactation are summarized. Each chapter includes 1-2 illustrative cases.

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Handbook of Commercial Policy explores three main topics that permeate the study of commercial policy. The first section presents a broad set of basic empirical facts regarding the pattern and evolution of commercial policy, with the second section investigating the crosscutting legal issues relating to the purpose and design of agreements. Finally, the third section covers key issues of commercial policy in the modern global economy. Every chapter in the book provides coverage from the perspectives of multilateral, and where appropriate, preferential trade agreements. While most other volumes are policy-oriented, this comprehensive guide explores the ways that intellectual thinking and rigor organize research, further making frontier-level synthesis and current theoretical and empirical research accessible to all.

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What new theories, evidence, explanations, and policies have shaped our studies of income distribution in the 21st century? Editors Tony Atkinson and Francois Bourguignon assemble the expertise of leading authorities in this survey of substantive issues. In two volumes they address subjects that were not covered in Volume 1 (2000), such as education, health and experimental economics; and subjects that were covered but where there have been substantial new developments, such as the historical study of income inequality and globalization. Some chapters discuss future growth areas, such as inheritance, the links between inequality and macro-economics and finance, and the distributional implications of climate change. They also update empirical advances and major changes in the policy environment.

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Principles of Electron Optics: Second Edition, Advanced Wave Optics provides a self-contained, modern account of electron optical phenomena with the Dirac or Schrödinger equation as a starting point. Knowledge of this branch of the subject is essential to understanding electron propagation in electron microscopes, electron holography and coherence. Sections in this new release include, Electron Interactions in Thin Specimens, Digital Image Processing, Acquisition, Sampling and Coding, Enhancement, Linear Restoration, Nonlinear Restoration – the Phase Problem, Three-dimensional Reconstruction, Image Analysis, Instrument Control, Vortex Beams, The Quantum Electron Microscope, and much more.

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Many hereditary cancer syndromes are linked to alterations in single genes. Detection and clinical interpretation of these alterations can guide cancer risk reduction for patients and their families through screening, prophylactic measures, and other strategies. Diagnosis and Management of Hereditary Cancer summarizes hereditary syndromes and their associated cancers and genes. The information is presented in 50 practice-enhancing tables that relate clinical, genetic, diagnostic, and management aspects in a manner that has previously not been available in a single reference. Intended to guide the specialist as well the novice, this volume will elevate the care of hereditary cancer patients and their families.

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There is a growing body of data supporting the usage of cannabis and cannabis-related products in alleviating or preventing symptoms in different diseases and conditions. Medicinal Usage of Cannabis and Cannabinoids offers readers a comprehensive reference on the medical usage and symptom relief provided by these compounds in a variety of disorders. With coverage of neurological diseases like Alzheimer’s and Parkinson’s, and a wide range of other afflictions including depression, anxiety, nausea, and cancer, this broad coverage allows readers to learn about symptom control but also physiological, psychological, and pharmacological effects of these compounds. Unique case reports are provided as well. This volume provides a platform for research on the use of these compounds in improving patient care, brain function, and neurological dysfunction.

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Reproductive and Developmental Toxicology, Third Edition is a comprehensive and authoritative resource, providing the latest literature on this complex subject by focusing on three core components - parent, placenta and fetus - and the continuous changes that occur in each. Enriched with relevant references describing every aspect of reproductive toxicology, this revised and updated resource addresses the totality of the subject, discussing a broad range of topics including nanoparticles and radiation, gases and solvents, smoking, alcohol and drugs of abuse, and metals, among others. In addition, it is the only resource to include reproductive and developmental toxicity in domestic animals, fish and wildlife With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages. Completely revised and updated to include the most recent developments in the field, this book is an essential resource for advanced students and researchers in toxicology, as well as biologists, pharmacologists and teratologists from academia, industry and regulatory agencies.

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MATLAB Programming for Biomedical Engineers and Scientists, Second Edition provides an easy-to-learn introduction to the fundamentals of computer programming in MATLAB. The book explains the principles of good programming practice, while also demonstrating how to write efficient and robust code that analyzes and visualizes biomedical data. Aimed at the biomedical engineering student, biomedical scientist and medical researcher with little or no computer programming experience, this is an excellent resource for learning the principles and practice of computer programming using MATLAB. The book enables the reader to analyze problems and apply structured design methods to produce elegant, efficient and well-structured program designs, implement a structured program design in MATLAB, write code that makes good use of MATLAB programming features, including control structures, functions and advanced data types, and much more.

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Data Mining: Concepts and Techniques, Fourth Edition introduces concepts, principles, and methods for mining patterns, knowledge, and models from various kinds of data for diverse applications. Specifically, it delves into the processes for uncovering patterns and knowledge from massive collections of data, known as knowledge discovery from data, or KDD. It focuses on the feasibility, usefulness, effectiveness, and scalability of data mining techniques for large data sets. After an introduction to the concept of data mining, the authors explain the methods for preprocessing, characterizing, and warehousing data. They then partition the data mining methods into several major tasks, introducing concepts and methods for mining frequent patterns, associations, and correlations for large data sets; data classificcation and model construction; cluster analysis; and outlier detection. Concepts and methods for deep learning are systematically introduced as one chapter. Finally, the book covers the trends, applications, and research frontiers in data mining.

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Computer and Information Security Handbook, Third Edition, provides the most current and complete reference on computer security available in one volume. The book offers deep coverage of an extremely wide range of issues in computer and cybersecurity theory, applications, and best practices, offering the latest insights into established and emerging technologies and advancements. With new parts devoted to such current topics as Cloud Security, Cyber-Physical Security, and Critical Infrastructure Security, the book now has 100 chapters written by leading experts in their fields, as well as 12 updated appendices and an expanded glossary. It continues its successful format of offering problem-solving techniques that use real-life case studies, checklists, hands-on exercises, question and answers, and summaries. Chapters new to this edition include such timely topics as Cyber Warfare, Endpoint Security, Ethical Hacking, Internet of Things Security, Nanoscale Networking and Communications Security, Social Engineering, System Forensics, Wireless Sensor Network Security, Verifying User and Host Identity, Detecting System Intrusions, Insider Threats, Security Certification and Standards Implementation, Metadata Forensics, Hard Drive Imaging, Context-Aware Multi-Factor Authentication, Cloud Security, Protecting Virtual Infrastructure, Penetration Testing, and much more. Online chapters can also be found on the book companion website: https://www.elsevier.com/books-and-journals/book-companion/9780128038437

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Sketching Working Experience: The Workbook provides information about the step-by-step process of the different sketching techniques. It offers methods called design thinking, as a way to think as a user, and sketching, a way to think as a designer. User-experience designers are designers who sketch based on their actions, interactions, and experiences. The book discusses the differences between the normal ways to sketch and sketching used by user-experience designers. It also describes some motivation on why a person should sketch and introduces the sketchbook. The book reviews the different sketching methods and the modules that contain a particular sketching method. It also explains how the sketching methods are used. Readers who are interested in learning, understanding, practicing, and teaching experience design, information design, interface design, and information architecture will find this book relevant.

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Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma: Translational and Clinical Outcomes, Volume Three provides comprehensive information about ongoing research and clinical data on liver cancer. The book presents detailed descriptions about diagnostics and therapeutic options for easy understanding, with a focus on precision medicine approaches to improve treatment outcomes. This updated volume discusses topics such as clinical and safety assessment of HCC patients, liver transplantation as a therapeutic option, immunotherapy interventions, and image-based surveillance. In addition, it discusses immunohistology of HCC-enabled precision medicine and artificial intelligence for hepatocellular carcinomas. This is a valuable resource for cancer researchers, oncologists, graduate students, hepathologists and members of biomedical research who need to understand more about liver cancer to apply in their research work or clinical setting.

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Cell Movement in Health and Disease brings the several scientific domains related to the phenomena together, establishing a consistent foundation for researchers in this exciting field. The content is presented in four main section. The first explores the foundations of Cell Movement, including overviews of cellular structure, signaling, physiology, motion-related proteins, and the interface with the cellular membrane. The second part covers the biological aspects of cellular movement, starting with chemical and mechanical sensing, describing the types of cell movement, mechanics at cell level, cell physiology, collective behavior, and the connections with the extracellular matrix. The following chapters provide an overview of the molecular machinery involved and cell-type specific movement. The third part of the book is dedicated to the translational aspects of cell movement, highlighting the key conditions associated with cell movement dysfunction, like cell invasion in cancer, wound healing, developmental issues, neurological dysfunctions, and immune response. The final part of the book covers key methods and modeling tools for cell movement research, including predictive mathematical models, in vitro and in vivo methods, biophysical and bioinformatics tools. Cell Movement in Health and Disease is the ideal reference for scientists from different backgrounds converging to expand the understanding of this key cellular process. Cellular and molecular biologists will gain a better understanding of the physical principals operating at cellular level while biophysicist and biomedical engineers will benefit from the solid biology foundation provided by the book.

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Stem Cells and COVID-19 presents up-to-date knowledge on the effect of hematopoietic and mesenchymal stem cells to combat SARS-CoV-2 infection in its diagnosis, treatment and prevention. In addition, the book critically discusses challenges, highlighting outstanding questions and future perspectives. Written by global experts in the field for both pre-clinical and clinical practitioners, this comprehensive book delves into how stem cells have a strong potential in developing better diagnostic, treatment and preventive strategies in SARS-CoV-2 infection. Both hematopoietic and mesenchymal stem cells are critical to better understand the response of immune system to coronavirus infection in both healthy and co-morbid conditions in the development of effective vaccines and immunotherapies.

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The newest addition to the Harris and Harris family of Digital Design and Computer Architecture books, this RISC-V Edition covers the fundamentals of digital logic design and reinforces logic concepts through the design of a RISC-V microprocessor. Combining an engaging and humorous writing style with an updated and hands-on approach to digital design, this book takes the reader from the fundamentals of digital logic to the actual design of a processor. By the end of this book, readers will be able to build their own RISC-V microprocessor and will have a top-to-bottom understanding of how it works. Beginning with digital logic gates and progressing to the design of combinational and sequential circuits, this book uses these fundamental building blocks as the basis for designing a RISC-V processor. SystemVerilog and VHDL are integrated throughout the text in examples illustrating the methods and techniques for CAD-based circuit design. The companion website includes a chapter on I/O systems with practical examples that show how to use SparkFun’s RED-V RedBoard to communicate with peripheral devices such as LCDs, Bluetooth radios, and motors. This book will be a valuable resource for students taking a course that combines digital logic and computer architecture or students taking a two-quarter sequence in digital logic and computer organization/architecture.

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The new edition of this well-known hybrid anatomy core text and atlas superbly depicts and describes the human body, so you can identify anatomical structures with confidence and have a clear understanding of the core anatomy you need. Now fully revised and updated, it is the only textbook and atlas of gross anatomy that illustrates all structures using high-quality dissection photographs AND clearly labelled line drawings for each photograph. This is combined with concise yet thorough text to support and explain all key human anatomy and clearly relate it to clinical practice. The complete, downloadable eBook (via Student Consult), enhanced with interactive self-assessment material, completes this superb, comprehensive resource. It will be particularly relevant to medical and dental students, as well as candidates preparing for higher surgical specialties and radiology. It will also be an invaluable, accessible guide for students in other professions where anatomy is an important component of the course. High quality, richly coloured dissection photographs show structures most likely to be seen and tested in the lab - helps you recognize and interpret gross specimens accurately Interpretive line drawings next to every photograph, with consistent colour-coding - helps you clearly identify structures and differentiate fat, muscle, ligament, etc. 'Clinical Skills' pages and new highlighting of the most clinically relevant text helps readers quickly understand how to apply knowledge of gross anatomy to the clinical setting New photographs reflect the latest imaging techniques as seen in current practice This book comes with the complete, downloadable eBook via STUDENT CONSULT- enhanced with new interactive self-assessment material to check understanding and aid exam preparation High quality, richly coloured dissection photographs show structures most likely to be seen and tested in the lab - helps you recognize and interpret gross specimens accurately Interpretive line drawings next to every photograph, with consistent colour-coding - helps you clearly identify structures and differentiate fat, muscle, ligament, etc. 'Clinical Skills' pages and new highlighting of the most clinically relevant text helps readers quickly understand how to apply knowledge of gross anatomy to the clinical setting New photographs reflect the latest imaging techniques as seen in current practice This book comes with the complete, downloadable eBook via STUDENT CONSULT - enhanced with new interactive self-assessment material to check understanding and aid exam preparation

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This is one of a two-volume work on neurocognitive development, focusing separately on normative and non-normative development. The normative volume focuses on neurology, biology, genetics, and psychology of normative cognitive development. It covers the development of intellectual abilities, visual perception, motor function, language, memory, attention, executive function, social cognition, learning abilities, and affect and behavior. The book identifies when and how these functions develop, the genetics and neurophysiology of their operation, and their evaluation and assessment in clinical practice. This book will serve as a comprehensive reference to researchers in cognitive development in neuroscience, psychology, and medicine, as well as to clinicians and allied health professionals focused on developmental disabilities (child neurologists, pediatric neuropsychologists, child psychiatrists, speech and language therapists, and occupational therapists.)

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The Neurology of HIV Infection covers all aspects of nervous system involvement and pathology in HIV-infected individuals. Specialists in this field cover epidemiology, global aspects, pathology and pathogenesis of nervous system disease in HIV-infection. All complications, including the pathology caused by HIV itself and all opportunistic infections of the nervous system are reviewed in detail. Both central nervous and peripheral nervous system complications, including neuropathies and myopathies, are discussed. Key chapters on global developments, HIV-associated neurocognitive disorders, IRIS, stroke and neuro-aids in children complete this volume.

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This is one volume of a two-volume work on neurocognitive development, focusing separately on normative and non-normative development. The disorders and disabilities volume focuses on disorders of intellectual abilities, language, learning memory as well as psychiatric developmental disorders. The developmental aspects of neurological diseases in children is also covered. Chapters discuss when and how these disorders develop, the genetics and neurophysiology of their operation, and their evaluation and assessment in clinical practice. Assessment, treatment, and long-term outcome are provided as well as advances in methods and tools for assessment. This book will serve as a comprehensive reference to researchers in cognitive development in neuroscience, psychology, and medicine, as well as to clinicians and allied health professionals focused on developmental disabilities (child neurologists, pediatric neuropsychologists, child psychiatrists, speech and language therapists, and occupational therapists.)

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Sex Differences in Neurology and Psychiatry, Volume 175, addresses this important issue by viewing major neurological and psychiatric conditions through the lens of sexual dimorphism, providing an entirely novel approach to understanding vulnerability factors, as well as potential new treatment strategies in several common neuropsychiatric disorders. The handbook comprises four major sections: (1) Introduction to sex differences in neuroanatomy and neurophysiology, (2) Description of the impact of genetic, epigenetic, sex hormonal and other environmental effects on cerebral sex dimorphism, (3) Review of sex differences in neurologic disorders, and (4) Review of sex differences in psychiatric disorders.

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