Search results for ""royal society of chemistry""

This book provides an interdisciplinary review of one of the great unsolved mysteries that has fascinated scientists for over 150 years: the origin of chirality in biomolecules. Current advances in fields as diverse as space exploration, prebiotic chemistry and high-energy physics may help to provide an answer. Important pieces of information will come from observations at the two frontiers of science: outer space and the subatomic world. Observation of distant planets, galaxies, and even actual sampling of celestial objects from beyond the solar system are projects currently underway. At the other end of the spectrum, there are experiments that study the elemental properties of matter, such as symmetry, and interactions with the fundamental forces. Completely revised and updated this new edition once again unifies all the theories of the origin of biomolecular homochirality together in a single source. This complete, interdisciplinary review of an intriguing subject condenses a large and disparate range of contributions from journals in almost every scientific field. The various theories have been organized, interrelated and explained in a unified way. It is fundamental, comprehensive and structured to be accessible for educational purposes.

Read more less

Implantable technologies allow for a sustained control over the release of pharmaceuticals into the bloodstream thereby achieving a controlled concentration with the potential to minimise side-effects while increasing patient compliance. Significant progress has been made in various alternative implantable delivery technologies, notably in intraocular and subcutaneous devices. Despite success in research and clinical studies, long-term clinical efficacy may be more limited and different aspects related to drug development and commercialization using these technologies are not well understood or practiced in the commercial setting. This book provides a comprehensive and cohesive picture of the latest in the field while also outlining the opportunities and challenges in implantable technology. Implantable Technologies: Pepties and Biologic Drug Development is an ideal reference for any postgraduate or researcher interested in utilising implantable technologies and novel routes of drug administration. The book will also be of interest to those involved in formulation and clinical application for a wide array of disease areas in addition to more established paradigms such as diabetes and pain management.

Read more less

Mechanobiology is a new research field that investigates how the physical forces and changes in mechanical properties of cells and tissues contribute to their development, physiology and disease. One unique feature in the mechanical regulation, distinct from chemical/biochemical one, is that it can directly react with the multi-layered architectures of living systems, ranging from nano-scale proteins, subcellular organelles, cells, tissues, organs to whole bodies; one could term it “mechanoarchitectonics”. Another important aspect is its time-dependent dynamic feature. Not only time evolution in cells and extracellular matrices, but their intrinsic viscoelastic nature makes mechanical interaction dissipative and such feature is critical in cellular mechanical responses. This book focuses on recent progress in mechanobiology from the materials science perspective, encompassing innovative material designs for force measurements and actuation to resolve dynamic mechanobiology and mechanoarchitectonics, by better mimicking physiologically relevant and time-evolving cellular mechanical environments. It also shows the marriage between cutting-edge materials science which enable spatiotemporal manipulation of material and cell dynamics in multi-dimensions and molecular biological techniques such as genome editing and next generation sequencing for cell fate/motility engineering and disease modelling, with the aim of providing valuable insights into the latest technological advances and discoveries in areas such as stem cell, fibroblast, heart, tumour, and epithelial mechanobiology. Edited by leaders in the field, this book will be suitable for a broad range of readers, including materials scientists, biomaterial and biomedical engineering researchers and those working in chemical and mechanical engineering to expand possibilities of system designs for the developments of medical technologies based on mechanobiology.

Read more less

Over the past decade, great strides have been taken in developing methodologies that can treat more and more complex nano- and nano-bio systems embedded in complex environments. Multiscale Dynamics Simulations covers methods including DFT/MM-MD, DFTB and semi-empirical QM/MM-MD, DFT/MMPOL as well as Machine-learning approaches to all of the above. Focusing on key methodological breakthroughs in the field, this book provides newcomers with a comprehensive menu of multiscale modelling options so that they can better chart their course in the nano/bio world.

Read more less

Electric-field-mediated chemistry is an emerging topic that is rapidly growing and fanning out in many directions. It involves theoretical and experimental aspects, as well as intense interplay between them, including breakthrough achievements such as the proof-of-principle that a Diels–Alder reaction, which involves two simultaneous C–C bond making events, can be catalysed or inhibited simply by changing the direction of an oriented external-electric field (OEEF). This productive interplay between the theoretical and experimental branches of chemistry is continuing, and gradually defining a new sub-field wherein various sources of electric fields, whether external or built-in and designed, or even surface induced fields (plasmons), are brought to bear on chemical reactions, molecular structures, and nano-systems, leading to control of reactivity, selectivity, chirality, molecular orientations, changes in structure, and in dynamics. Written by leaders in the field, Effects of Electric Fields on Structure and Reactivity is the first book on this exciting topic. Starting with an overview of the theory behind – and demonstrations of the effect of – electric fields on structure and reactivity, this accessible reference work aims to encourage those new to the field to consider harnessing these effects in their own work. Covering applications and recent theoretical developments, it is a useful resource for theoretical chemists and experimentalists alike.

Read more less

This book provides a summary of the main obstacles for creating and maintaining high standards of health and safety in higher education and research organisations. The obstacles include high staff turnover and an uncertain and constantly evolving research environment, small groups lacking unified management structure, deadline time pressures, restricted funding models and existing "old school" culture. Often the Health and Safety specialists and personnel managers in these organisations find themselves reiterating the same information, which gets lost as soon as the new cohort of workers arrives. Providing insight into methods of managing health and safety, training, and supervision, which help to build a strong and reliable health and safety system, this book is a collection of "best practices" from experienced safety professionals and researchers in Europe and the United States. These experiences demonstrate how health and safety professionals have overcome these issues and provide readers with ideas and models they can use in their own organisations. The information contained within is aimed at health and safety professionals and managers in universities and research organisations conducting scientific and engineering research with transient workers and students worldwide.

Read more less

Microalgae are a group of single-celled, photosynthetic microorganisms. They are of great commercial interest as they are capable of producing biomass (with a vast array of biochemical) using sunlight, CO2 and various other naturally occurring nutrients. Correctly utilised, they have the potential to provide sustainable supply of commercially relevant biochemicals, biofuels, nutraceuticals, food and feed supplements. The field of microalgal biotechnology is a fast-paced area of research, with technologies coming ever closer to commercial viability. Microalgal Biotechnology consolidates the latest research in the field together with a look at market potential and policy considerations. Highlighting the huge potential of microalgae as commercial commodities, it covers progress on various fronts including; bio-refinery and its technological challenges, genetic engineering, biosafety and regulatory issues, open and closed photo-bioreactors for biomass production, market space and sustainability for algal products. This book is a useful resource for researchers, academicians, postgraduate students, industries, policy makers and anyone interested in the status and future possibilities of microalgae commercialisation.

Read more less

This volume brings together established and early-career scientists, post-graduate students and industrial researchers to cover a wide range of topical subjects across organic photonics and electronics and related fields.

Read more less

Including introductions to statistical distributions, regression analysis, the elementary physics of airborne particles and gases and epidemiological techniques this book is a useful addition to any air pollution course.

Read more less

This volume brings together internationally leading researchers in this interdisciplinary field to explore and exchange ideas, both experimental and theoretical, to further our understanding of the fundamental properties of water at interfaces.

Read more less

The book focuses on how sustainable nanomaterials can helpwith various aspects of infectious diseases, including prevention, diagnosis, and treatment, as well as the characteristics that materials should possess in order to enter clinical trials.

Read more less

There is an increasing awareness that materials and chemicals produced from fossil fuels are not sustainable, both in terms of the pollution caused by the extraction and production processes, and the fact that there is only a finite supply of these fossil fuels. Therefore, there is a strong incentive to find sources for chemicals and materials from source materials that we know we can continue to generate. Plants are a source of a wide variety of chemicals, many with interesting properties, and these chemical feedstocks are considered renewable rather than finite. Green Chemistry and Green Materials from Plant Oils and Natural Acids covers the application of these natural materials in producing polymers, lubricants and plasticisers.

Read more less

Perfluoroalkyl and polyfluoroalkyl substances (PFASs) are extensively used in consumer products, despite their high persistence and other hazards. The risks posed by this chemical class to human health and the environment, which are increasingly becoming understood, have triggered regulation and policy changes. However, safer alternatives to these technically effective materials and methods to discover and use those alternatives are still under development. Remediation of PFAS contaminated sites will not solve the growing worldwide pollution, but substitution with safer substances at the formulation and manufacturing phases will at least abate the flow of PFASs into our bodies and environment. Introducing safer alternatives to some of the PFASs of concern used in select industry sectors, this book informs the reader about the processes of chemical hazard and alternatives assessment that can foster innovation. It is a valuable resource for both green chemists and industrial chemists interested in how they can make their products safer without compromising on function.

Read more less

Photodynamic therapy (PDT) is increasingly used among health practitioners in combatting a variety of diseases, most notably various types of cancer, and is often utilised in combination with other therapeutic options to enhance efficacy or reduce adverse reactions. Combination Therapies Involving Photodynamic Therapy reviews the current state of development of PDT and presents the foreseeable advancements of combination approaches to therapeutic strategies. This book represents a novel approach to the therapeutic applications of five different technologies including the combinations of photodynamic therapy, photothermal hyperthermia therapy, magnetic hyperthermia therapy, chemotherapy, and cold atmospheric pressure plasma therapy. An ideal companion for students, researchers and practitioners in biological sciences, biotechnology, and photobiological and photochemical sciences, as well as medicinal and pharmaceutical chemistry.

Read more less

Extracellular and biofluids vesicles (EVs) are highly specialised yet ubiquitous nanoscale messengers secreted by cells. With the development of stem cell engineering, EVs promise to deliver next generation tools in regenerative medicine and tissue engineering, as well as in diagnostics. A vibrant and promising field, this book provides the first resource to the field. Covering basic cell biology, including EV production and intracellular communication, this book will provide material scientists and engineers with a foundation to the necessary biology. The reader will then learn about the isolation of extracellular vesicles their physicochemical characterisation and therapeutic application of EVs in regenerative medicine as well as their potential as biomarkers in medical diagnostic. This book will also discuss the regulatory landscape of EVs. Bridging cell biology, biomaterials, biophysics and biomedical engineering the content of this book is written with a broad interdisciplinary audience in mind. Researchers, new and established will find this a must-have on their shelf.

Read more less

Presenting an up-to-date review of the state-of-the-art and main applications of omics technologies to current hot topics in food sciences, this book is divided into four convenient sections. The first section represents an introduction to the development of foodomics and will provide a general overview of DNA-based and protein-based methods. The second section is focused on the main applications of omics to food safety issues, such as chemical hazards, foodborne pathogens, phages, food authentication or GMO detection. The third section is focused on specific food groups and how omics have revolutionized the investigation of dairy and meat products, seafood, agricultural and fermented food products. Finally, the fourth section is devoted to the link between foodomics and health: hot topics such as nutrimetabolomics, food allergy or probiotics are reviewed here. The book brings together work from top international scientists to produce the most significant academic book for some years on omics and food for a broad audience. It presents unique features not covered so far by other books, such as a detailed description of different strategies and applications of omics techniques to many food sectors and provides a welcome addition to the cutting-edge literature in this area for researchers and professionals in food science and food chemistry.

Read more less

Traditionally, dietary fat has been associated with negative effects on human health by consumers due to its high energy density. However, today it is well known that the quality of the fat ingested is more important than its quantity, and that there are natural lipophilic compounds that are essential for the correct maintenance of human physiological functions. For this reason, the negative image associated with dietary fat consumption is not fully justified. Dietary fat is a hot research area that has attracted increasing attention in the last decades. An adequate intake of dietary fats adapted to our age and physical activity, as well as an increase in the intake of beneficial fatty compounds and controlling the intake of those types of fats that have negative effects on our health, can be powerful allies in preventing the development of chronic non-communicable diseases. Through this book, the Editors have compiled the most up to date and well-documented information on many aspects of the development and application of novel dietary patterns related to fatty compounds, with special emphasis on beneficial effects. They have considered fatty nutritional requirements at different stages of life, the international guidelines and the application of new -omics techniques, such as epigenetics, nutrigenomics, metabolomics and metagenomics, related to human health. This book will be of interest to researchers in food technology and biomedicine, as well as the food industry and food distribution areas.

Read more less

Polymers with redox properties are electroactive macromolecules containing localized sites or groups that can be oxidized and reduced. Depending on the oxidation state, redox polymers can present different electronic, optical, mechanical or chemical properties. These polymers are finding new applications in materials science, as well as being included in the design of a number of electrochemical devices. Redox Polymers for Energy and Nanomedicine highlights trends in the chemistry, characterization and application of polymers with redox properties. The book starts with an introduction to redox polymers and covers several important topics including redox polymer types, state-of-the-art characterization techniques, synthetic strategies and theory and computational studies. The second part is devoted to the redox polymers applied in energy and nanomedicine. First, the most important redox polymer families in energy storage are reviewed, i.e, radical, phenothiazine, carbonyl and catechol containing polymers. The book also contains recent developments in redox polymers for biofuel cells and all-organic batteries. Second, the emerging applications of redox polymers in nanomedicine technologies such as, tissue engineering, drug-delivery, actuators or biosensors are explained in detail. With contributions from global experts, the book will be of interest to graduate students and researchers working in polymer science, electrochemistry, energy research and nanomedicine.

Read more less

While our five senses are doing a reasonably good job at representing the world around us on a macro-scale, we have no existing intuitive representation of the nanoworld, ruled by laws entirely foreign to our experience. This is where molecules mingle to create proteins; where you wouldn't recognize water as a liquid; and where minute morphological changes would reveal how much 'solid' things, such as the ground or houses, are constantly vibrating and moving. Following in the footsteps of Nano-Society and Nanotechnology: The Future is Tiny, this title introduces a new collection of stories demonstrating recent research in the field of nanotechnology. This drives home the fact that a plethora of nanotechnology R&D will become an integral part of improved and entirely novel materials, products, and applications yet will remain entirely invisible to the user. The book gives a personal perspective on how nanotechnologies are created and developed, and will appeal to anyone who has an interest in the research and future of nanotechnology. Reviews of Nanotechnology: The Future is Tiny: 'The book is recommended not only to all interested scientists, but also to students who are looking for a quick and clear introduction to various research areas of nanotechnology' Angew. Chem., 2017, 56(26), 7351–7351 'Once you start reading you will find it very difficult to stop' Chromatographia, 2017, 80, 1821

Read more less

This book discusses the chemistry of food proteins and peptides and their relationship with nutritional, functional, and health applications. Bringing together authorities in the field, it provides a comprehensive discussion focused on fundamental chemistries and mechanisms underpinning the structure-function relationships of food proteins and peptides. The functional and bioactive properties hinge on their structural features such as amino acid sequence, molecular size, hydrophobicity, hydrophilicity, and net charges. The book includes coverage of advances in the nutritional and health applications of protein and peptide modifications; novel applications of food proteins and peptides in the development of edible functional biomaterials; advances in the use of proteomics and peptidomics for food proteins and peptide analysis (foodomics); and the relevance of food protein and peptide chemistries in policy and regulation. Research into the fundamental chemistries behind the functional, health and nutritional benefits is burgeoning and has gained the interest of scientists, the industry, regulatory agencies, and consumers. This book fills the knowledge gap providing an excellent source of information for researchers, instructors, students, food and nutrition industry, and policy makers.

Read more less

Providing detailed information on key areas of post-harvest technologies, this book is written with small-scale processors and entrepreneurs in food processing, who have no formal training in Food Science or Food Engineering, in mind. Uniquely, it will review the hands-on aspects of food processing from a largely non-academic viewpoint. It is written in non-technical language and covers everything from the basic science of why food is processed to a description of the main methods used. Coverage includes all current technologies that are used at the small-scale such as why food is processed, the historical development of food processing, background skills, heating and cooling in food processing, thermal processing basics and specialised calculations, drying food materials, statistical manufacturing control and sugar solution calculations in beverage making The target audience for this book is vastly under-served with appropriate information and the abundant use of photographs, showing the various concepts described in the text, makes this book appealing to those required to understand their food process operations.

Read more less

Insight into the role of hormones, particularly estrogen and testosterone, in health and disease etiology – including interactions with other hormone pathways – has dramatically changed. Estrogen and androgen receptors, with their polymorphisms, are key molecules in all tissues and are involved in a number of homeostatic mechanisms but also pathological processes including carcinogenesis and the development of metabolic and neurological disorders such as diabetes and Alzheimer’s disease. Endocrine disrupting chemicals (EDCs) can interfere with the endocrine (hormone) systems at certain dosages and play a key role in the pathology of disease. Most known EDCs are manmade and are therefore an increasing concern given the number commonly found in household products and the environment. This book will cover the mechanisms of EDC pathology across the spectrum of disease, as well as risk assessment and government and legal regulation to provide a holistic view of the current issues and cutting-edge research in the topic. With contributions from global leaders in the field, this book will be an ideal reference for toxicologists, endocrinologists and researchers interested in developmental biology, regulatory toxicology and the interface between environment and human health.

Read more less

Research and new tools in biomaterials development by using peptides are currently growing, as more functional and versatile building blocks are used to design a host of functional biomaterials via chemical modifications for health care applications. It is a field that is attracting researchers from across soft matter science, molecular engineering and biomaterials science. Covering the fundamental concepts of self-assembly, design and synthesis of peptides, this book will provide a solid introduction to the field for those interested in developing functional biomaterials by using peptide derivatives. The bioactive nature of the peptides and their physical properties are discussed in various applications in biomedicine. This book will help researchers and students working in biomaterials and biomedicine fields and help their understanding of modulating biological processes for disease diagnosis and treatments.

Read more less

Anthropogenic radionuclides have been introduced into the environment by incidents such as nuclear weapon tests, accidents in nuclear power plants, transport accidents and accidental or authorised discharges from nuclear facilities. Scientists need accurate analysis of these radionuclides in order to estimate the risk to the public from released radioactivity. This book is a snapshot of the work of leading scientists from across the globe on environmental radiochemistry and radioecology, nuclear forensics and radiation detection, radioanalytical techniques and nuclear industry applications. The research contributions were first presented at the 13th International Symposium on Nuclear and Environmental Radiochemical Analysis in September 2018. This essential work provides a key reference for graduates and professionals who work across fields involving analytical chemistry, radiochemistry, environmental science and technology, and waste disposal.

Read more less

In recent years, in situ analysis of cellular functional molecules has attracted considerable interest as it can provide spatially or temporally resolved information of these essential molecules on/within living cells in a non-invasive way. In Situ Analysis of Cellular Functional Molecules introduces the tailor-made design of detection probes as well as schemes from a top-down perspective according to the unique characteristics of cellular functional molecules. The latest methodological developments, including enhancement of detection sensitivity and specificity, precision localization, implementation of dynamic tracking, and acquirement of quantitative functional information for various important functional molecules is discussed in detail. Written by leaders in the field, this book will provide a comprehensive overview to scientists in academia and professionals in industry working on different aspects of cellular analysis and cell biology.

Read more less

Metabolomics and proteomics allow deep insights into the chemistry and physiology of biological systems. This book expounds open-source programs, platforms and programming tools for analysing metabolomics and proteomics mass spectrometry data. In contrast to commercial software, open-source software is created by the academic community, which facilitates the direct interaction between users and developers and accelerates the implementation of new concepts and ideas. The first section of the book covers the basics of mass spectrometry, experimental strategies, data operations, the open-source philosophy, metabolomics, proteomics and statistics/ data mining. In the second section, active programmers and users describe available software packages. Included tutorials, datasets and code examples can be used for training and for building custom workflows. Finally, every reader is invited to participate in the open science movement.

Read more less

Inorganic and organometallic polymers feature many attractive properties that are useful for the design of diverse functional materials. Emphasising concepts that inform polymer design, synthesis and applications, readers of this book will gain a complete understanding of the introduction to inorganic and organometallic polymer science that will further their studies in materials science, chemistry and engineering. The first chapter lays down the core concepts that the book builds from, including polymerisation and naming conventions. It also reveals why some organometallic polymers are better suited than organic polymers in certain applications. Subsequent chapters discuss the chemistry of metals in particular the transition metals as they relate to polymer properties, before walking the reader through in-depth chapters on synthesis, structure, properties, characterization, and examples of inorganic and organometallic polymers. The final chapter presents applications of these polymers in diverse fields ranging from biomedicine, energy to catalysis. Worked examples and exercises are provided at the end of each chapter to assist students in assessing their understanding of these concepts, and journal references are included to direct students to published literature related to inorganic and organometallic polymers. Ideal for lecturers teaching a one semester advanced undergraduate and graduate courses in polymer science, as well as for self-study researchers and industrial chemists that are working with polymers, this book provides the user with a complete and expert grounding to the field.

Read more less

Without interstellar dust, the Universe as we see it today would not exist. Yet at first we considered this vital ingredient merely an irritating fog that prevented a clear view of the stars and nebulae in the Milky Way and other galaxies. We now know that interstellar dust has essential roles in the physics and chemistry of the formation of stars and planetary systems, the creation of the building blocks of life, and in the movement of those molecules to new planets. This is the story in this book. After introducing the materials this interstellar dust is made of, the authors explain the range of sizes and shapes of the dust grains in the Milky Way galaxy and the life cycle of dust, starting from the origins of dust grains in stellar explosions through to their turbulent destruction. Later on we see the variety of processes in interstellar space involving dust and the events there that cause the dust to change in ways that astronomers and astrobiologists can use to indirectly observe those events. This book is written for a general audience, concentrating on ideas rather than detailed mathematics and chemical formulae, and is the first time interstellar dust has been discussed at an accessible level.

Read more less

Fibrosis is a condition with globally high unmet medical need, and as such is a highly active area of academic and pharmaceutical research covering multiple treatment targets, organs, tissues and therapeutic approaches. Anti-fibrotic Drug Discovery is a single source reference for the latest drug-discovery approaches to tackle fibrosis in various tissues, comprehensively covering recent success and future perspectives on emerging therapeutic intervention points. The book highlights significant pre-clinical and clinical drugs currently being developed globally for this disorder. This book is ideal for postgraduate students and researchers with an interest in anti-fibrotic drug discovery as well as clinicians specialising in liver, kidney, heart and lung disease, in which fibrosis plays a key role in pathology.

Read more less

Chemical analysis requires solvents, reagents and energy and generates waste. The main goal of green analytical chemistry is to avoid or reduce the undesirable environmental side effects of chemical analysis, while preserving the classic analytical parameters of accuracy, sensitivity, selectivity and precision. This book portrays the current and changing situation concerning adoption of the principles of green chemistry as applied to analysis. It begins by looking at the advantages of and problems associated with on-site analysis and how analytical techniques can lead to increased productivity, efficiency and accuracy, and thereby reduce the consumption of materials. It then focuses on sample preparation techniques minimising solvent consumption or using alternative solvents, concepts and methods of improving the ‘greenness’ of instrumental analysis where miniaturization is an important part, separation methods from the perspective of green analytical chemistry and chemometrics approaches, which can reduce or can even remove the need for conventional steps in chemical analysis. Aimed at graduates and novices just entering the field, managers of analytical research laboratories, teachers of analytical chemistry and green public policy makers, this title will be a useful addition to any analytical scientist's library.

Read more less

Thermoelectric materials have received a great deal of attention in energy-harvesting and cooling applications, primarily due to their intrinsic low cost, energy efficient and eco-friendly nature. The past decade has witnessed heretofore-unseen advances in organic-based thermoelectric materials and devices. This title summarises the significant progress that has been made in the molecular design, physical characterization, and performance optimization of organic thermoelectric materials, focusing on effective routes to minimize thermal conductivity and maximize power factor. Featuring a series of state-of-the-art strategies for enhancing the thermoelectric figure of merit (ZT) of organic thermoelectricity, and highlighting cutting-edge concepts to promote the performance of organic thermoelectricity, chapters will strengthen the exploration of new high-ZT thermoelectric materials and their potential applications. With contributions from leading worldwide authors, Organic Thermoelectric Materials will appeal to graduate students as well as academic and industrial researchers across chemistry, materials science, physics and engineering interested in the materials and their applications.

Read more less

Academic and industrial research around polymer-based colloids is huge, driven both by the development of mature technologies, e.g. latexes for coatings, as well as the advancement of new materials and applications, such as building blocks for 2D/3D structures and medicine. Edited by two world-renowned leaders in polymer science and engineering, this is a fundamental text for the field. Based on a specialised course by the editors, this book provides the reader with an invaluable single source of reference. The first section describes formation, explaining basic properties of emulsions and dispersion polymerization, microfluidic approaches to produce polymer-based colloids and formation via directed self-assembly. The next section details characterisation methodologies from microscopy and small angle scattering, to surface science and simulations. The final chapters close with applications, including Pickering emulsions and molecular engineering for materials development. A comprehensive guide to polymer colloids, with contributions by leaders in their respective areas, this book is a must-have for researchers and practitioners working across polymers, soft matter and chemical and molecular engineering.

Read more less

CHEMISTRY STUDENT GUIDES. GUIDED BY STUDENTS For any student who has ever struggled with a mathematical understanding of chemistry, this book is for you. Mathematics is the essential tool for physical scientists. We know that confidence in using mathematics early on in a chemistry degree builds a solid foundation for further study. However, applying the abstract mathematics taught in schools to chemical phenomena is one of the biggest challenges that chemistry students face. In this book, we take a ‘chemistry-first’ approach. We link the mathematics to recognisable chemical concepts, building on high school chemistry, to facilitate deeper understanding. We cover the practical mathematical skills, including representation of data as tables and graphs, and give an overview of error handling in the physical sciences. More advanced mathematical concepts are introduced, using calculus to determine kinetic rate laws, intermolecular forces and in quantifying energetic change in thermodynamics. We also introduce the concept of the complex number and its role in considering quantum wave functions, widely used in computational chemistry. There are worked examples and problem sets to provide plenty of practise material to build proficiency. We also include insights from real students, which identify common problem areas and provide the prompts that helped them to overcome these. Chemistry Student Guides are written with current students involved at every stage, guiding the books towards the most challenging aspects of the topic.

Read more less

Nutraceuticals is a broad umbrella term used to describe any product derived from food sources with extra health benefits in addition to the basic nutritional value found in foods. This book is a comprehensive look at two themes in the area: technical and biological considerations. Technical considerations include an in-depth look at the process of bioactive identification and extraction and factors controlling bioactive concentrations in food. It also includes details of how these products are regulated and the steps necessary to utilize these products in human populations. Biological considerations include looking at how these products can be used in the prevention and treatment of chronic diseases, and a discussion on the process of formulations and how these influence bioavailability. This will be the first book to comprehensively examine the entire process of nutraceutical development from food to supplement creation and all the important considerations in between. This serves as an excellent and up-to-date reference for food scientists, food chemists, researchers in nutraceuticals and human nutrition.

Read more less

Modern printing technology has paved the way for the fabrication of thin inexpensive electronics and is now established as a topic taught on advanced level courses across materials science and engineering. The properties of printed electronics, such as thin-form factor, flexibility, stretchability, portability, and rollability mean that they have a wide range of applications, including in wearable devices, smart packaging, healthcare, and the automotive industry. This book describes the key printing technologies for printed electronics. Chapters cover principles and mechanisms, techniques, inorganic and organic materials, substrates, post-treatment and applications of printed electronics technologies. Written by a leader in the field, this title will be essential reading for students on courses across materials science, electronics science, manufacturing and engineering, as well as those with an interest in printed electronics.

Read more less

From pathology to treatment, MicroRNAs in Diseases and Disorders highlights the role of microRNAs (miRNAs) in the development and progression of a variety of diseases, including cancer, neurological disease, endocrine disease and autoimmune disease, and underscores the utilization of miRNA targets in the treatment of these conditions. Providing a comprehensive account, this book also includes the identification of miRNAs as diagnostic and prognostic biomarkers for disease, as well as evaluates translational value from clinical trials using synthesized and functionalized miRNA mimics and inhibitors. With a global contribution list and chapters from leading experts across the field, MicroRNAs in Diseases and Disorders is an invaluable reference to miRNA researchers and health professionals in a variety of disease areas in government, academia and industry. The book will also appeal to pharmaceutical and medicinal chemists with an interest in miRNA targeting therapeutics, as well as to advanced students in chemical biology and drug discovery.

Read more less

Amphiphilic polymer co-networks (APCNs) are a type of polymeric hydrogel, their hydrophobic polymer segments and hydrophilic components produce less aqueous swelling, giving better mechanical properties than conventional hydrogels. This new class of polymers is attracting increasing attention, resulting in further basic research on the system, as well as new applications. This book focuses on new developments in the field of APCNs, and is organised in four sections: synthesis, properties, applications and modelling. Co-network architectures included in the book chapters are mainly those deriving from hydrophobic macro-cross-linkers, representing the classical approach; however, more modern designs are also presented. Properties of interest discussed include aqueous swelling, thermophysical and mechanical properties, self-assembly, electrical actuation, and protein adsorption. Applications described in the book chapters include the use of co-networks as soft contact lenses, scaffolds for drug delivery and tissue engineering, matrices for heterogeneous biocatalysis, and membranes of controllable permeability. Finally, an important theory chapter on the modelling of the self-assembly of APCNs is also included. The book is suitable for graduate students and researchers interested in hydrogels, polymer networks, polymer chemistry, block copolymers, self-assembly and nanomaterials, as well as their applications in contact lenses, drug delivery, tissue engineering, membranes and biocatalysis.

Read more less

Providing critical reviews of recent advances in photochemistry, including computational and organic aspects, the latest volume in the series reflects the current interests in this area. It includes a series of highlights on photorelease processes (via two-photon excitation and Norrish type II reactions), the design of light-activated tissue bonding, photoresponsive molecular devices targeting nucleic acids, ECL based biosensing techniques, photochemical bond activation at metal centres, photoredox catalysis via aromatic hydrocarbons, photoinduced multicomponent reactions and asymmetric catalysis via triplet-state. This is essential reading for anyone wanting to keep up to date with the literature on photochemistry and its applications.

Read more less

The technique of Quasi-Elastic Neutron Scattering (QENS) is a powerful experimental tool for extracting temporal and spatial information at the nanoscale from both soft and hard condensed matter systems. However, while seemingly simple, the method is beset with sensitivities that, if ill considered, can hinder data interpretation and possibly publication. By highlighting key theoretical and data evaluation aspects of the technique, this specialised ‘primer style’ training resource encourages research success by guiding new researchers through a typical QENS experiment; from planning and sample preparation considerations to data reduction and subsequent analysis. Research examples are referenced throughout to illustrate the concepts addressed, with the book being written in such a way that it remains accessible to chemists, biologists, physicists, and materials scientists.

Read more less

Often described as ‘nature’s perfect food’, perceptions of egg consumption and human health have evolved substantially over the past decades, in particular dietary guidelines no longer include a limit for dietary cholesterol and recommend eggs as part of healthy eating patterns. This book presents the opportunities for processing eggs to produce value-added food, nutritional, biomedical, functional food, and nutraceutical applications. It provides new evidence around egg consumption with respect to cardiovascular diseases, metabolic syndrome, weight management, mental development, eye, muscle, and ageing health. It also highlights the new discovery regarding egg bioactives that are relevant to anti-oxidants, anti-inflammation, cardiovascular and bone health, anti-microbial and anti-viral activities. Appealing to food scientists, food chemists, researchers in human nutrition specialising in eggs and dairy nutrition, and those involved in egg production, this book is reflecting the trends and innovations in this area of research.

Read more less

Following the success of the first edition, this fully updated and revised book continues to provide an interdisciplinary introduction to sustainability issues in the context of chemistry and chemical technology. Its prime objective is to equip young chemists (and others) to more fully to appreciate, defend and promote the role that chemistry and its practitioners play in moving towards a society better able to control, manage and ameliorate its impact on the ecosphere. To do this, it is necessary to set the ideas, concepts, achievements and challenges of chemistry and its application in the context of its environmental impact, past, present and future, and of the changes needed to bring about a more sustainable yet equitable world. Progress since 2010 is reflected by the inclusion of the latest research and thinking, selected and discussed to put the advances concisely in a much wider setting - historic, scientific, technological, intellectual and societal. The treatment also examines the complexities and additional challenges arising from public and media attitudes to science and technology and associated controversies and from the difficulties in reconciling environmental protection and global development. While the book stresses the central importance of rigour in the collection and treatment of evidence and reason in decision-making, to ensure that it meets the needs of an extensive community of students, it is broad in scope, rather than deep. It is, therefore, appropriate for a wide audience, including all practising scientists and technologists.

Read more less

This book offers a state-of-the-art view of leather making, based on the scientific principles underpinning the technology. In particular, it contributes to the understanding of the modern leather industry, allowing practitioners to make judgements about day-to-day problems in the tannery and how change can be applied in a predictable way. Major themes running through the book are the economics and environmental impact of leather making and how these will ensure the sustainability of the industry. This second edition of Tony Covington’s Tanning Chemistry is a revision, update and extension in collaboration with a new co-author, Will Wise. The update reflects the advances made in the past decade, including a discussion of the impact of new information concerning the chemistry of sulfide. The original chapters have been re-organised and new chapters on novel modes of reagent delivery and the principles of finishing are now included. Enzymology is addressed as a separate topic, as are environmental impact and the future of leather. The book will be useful to all those involved in the supply chain, from farm, through students, chemical suppliers and tanners, to leather goods brands. Leather science is the key to understanding leather technology, to make it work, to make it work better and to keep it ahead of the competition.

Read more less

In recent years polymerisation using organocatalysts has become an appealing alternative to more traditional metal-based catalysts. Conferring numerous advantages including low cost and ease of use, as well as the ability to precisely control the synthesis of advanced polymer structures, organocatalysts are increasingly used in polymer synthesis. Organic Catalysis for Polymerisation provides a holistic overview of the field, covering all process in the polymer synthesis pathway that are catalysed by organic catalysts. Sub-divided into two key sections for ease of use, the first focuses on recent developments in catalysis and the applications of catalysts to the full range of polymerisations that they have been utilised in; the second concerning monomers, arranges the field by monomer type and polymerisation mechanism. The book will therefore, provide a complimentary view of the field, providing both an overview of state-of-the-art catalyst development and also the best methodologies available to create specific polymer types. Edited by leading figures in the field and featuring contributions from researchers across the globe, this title will serve as an excellent reference for postgraduate students and researchers in both academia and industry interested in polymer chemistry, organic chemistry, catalysis and materials science.

Read more less

Polyurethane nanocomposites present an attractive and sustainable way for designing smart materials that can be used in packaging, health and energy applications. Biobased Smart Polyurethane Nanocomposites brings together the most recent research in the field from the basic concepts through to their applications. Special emphasis is given to sustainable biodegradable polyurethane nanocomposites with hyperbranched architecture. The book introduces biobased polyurethanes and the nanomaterials that can be used as nanocomposites followed by the resulting polyurethane nanocomposites. The second part then explores important applications in paints and surface coatings, shape memory, self-healing, self-cleaning, biomaterials and packaging materials. Written by a leading expert on polyurethane nanocomposites, the book is a great introduction to this smart material and its applications.

Read more less

Self-propelled objects (particles, droplets) are autonomous agents that can convert energy from the environment into motion. These motions include nonlinear behaviour such as oscillations, synchronization, bifurcation, and pattern formation. In recent years, there has been much interest in self-propelled objects for their potential role in mass transport or their use as carriers in confined spaces. An improved understanding of self-organized motion has even allowed researchers to design objects for specific motion. This book gives an overview of the principles of self-propelled motion in chemical objects (particles, droplets) far from their thermodynamic equilibrium, at various spatial scales. Theoretical aspects, the characteristics of the motion and the design procedures of such systems are discussed from the viewpoint of nonlinear dynamics and examples of applications for these nonlinear systems are provided. This book is suitable for researchers and graduate students interested in physical and theoretical chemistry as well as soft matter.

Read more less

Gels are used in a large variety of commercial and scientific products from drug delivery systems and food science to biomedical sensors. They also are invaluable in MRI physics research where they mimic biological tissue and in radiotherapy quality assurance where they are used to capture the three dimensional radiation dose distribution. This unique book discusses the state-of-the-art of NMR and MRI techniques in studying the physics and chemistry of gel systems, in their application as MRI phantoms and as three dimensional radiation dosimeters. The first part of the book will cover the fundamental physical concepts of gels and the NMR techniques to study gel systems. The second part is dedicated to the application of gels in the life sciences and in the medical practice to validate radiotherapy and new MRI techniques. Filling the gap in literature, this volume provides the scientific reader with an extensive overview of possible techniques and methods to study the interesting properties and applications of gels. For the MRI researcher and medical physicist, the book will be a valuable resource in using gel phantoms for validating contemporary MRI techniques and radiotherapy treatments.

Read more less

Field-cycling NMR relaxometry is evolving into a methodology of widespread interest with recent technological developments resulting in powerful and versatile commercial instruments. Polymers, liquid crystals, biomaterials, porous media, tissue, cement and many other materials of practical importance can be studied using this technique. This book summarises the expertise of leading scientists in the area and the editor is well placed, after four decades of working in this field, to ensure a broad ranging and high quality title. Starting with an overview of the basic principles of the technique and the scope of its use, the content then develops to look at theory, instrumentation, practical limitations and applications in different systems. Newcomers to the field will find this book invaluable for successful use of the technique. Researchers already in academic and industrial settings, interested in molecular dynamics and magnetic resonance, will discover an important addition to the literature.

Read more less

Concerns about the adverse health effects of chemicals and radiation present in the environment and at workplaces have created the need for better detection systems to assess their potential to cause DNA damage in humans and other organisms across ecosystems. The Micronucleus Assay in Toxicology is the first comprehensive volume concerning the use of micronucleus assays in genetic toxicology. It succinctly explains the mechanisms by which genotoxins cause micronucleus formation and its relation to diseases. Furthermore, it describes the methods which are currently used for the analyses of micronuclei in different types of cells in human in vivo biomonitoring studies, routine in vivo tests with rodents, in vitro studies with human and mammalian cells, environmental monitoring with invertebrates and vertebrates such as molluscs, fish and, also, in plant bioassays. Moreover, this book also focuses on the use of the micronucleus technique in other research areas, including the detection of DNA damage caused by important groups of genotoxic carcinogens (heavy metals, industrial chemicals, cytotoxic drugs, pesticides, ionising radiation, etc.) as well as study designs, statistical analyses, international regulatory guidelines, and the development of automated scoring devices for this assay. This book will serve as both, a reference and a guide to students, and investigators in biomedical, biochemical and pharmaceutical sciences interested in gaining a better understanding of the biology of micronuclei and their application in measuring DNA damage caused by natural or man-made genotoxins.

Read more less