Search results for ""wiley-vch verlag gmbh""

Biomedical Engineering An exploration of materials processing and engineering technology across a wide range of medical applications The field of biomedical engineering has played a vital role in the progression of medical development technology. Biomedical Engineering: Materials, Technology, and Applications covers key aspects of the field—from basic concepts to advanced level research for medical applications. The book stands as a source of inspiration for research on materials as well as their development and practical application within specialized industries. It begins with a discussion of what biomedical engineering is and concludes with a final chapter on the advancements of biomaterials technology in medicine. Offers comprehensive coverage of topics, including biomaterials, tissue engineering, bioreceptor interactions, and various medical applications Discusses applications in critical industries such as biomedical diagnosis, pharmaceutics, drug delivery, cancer detection, and more Serves as a reference for those in scientific, medical, and academic fields Biomedical Engineering takes an interdisciplinary look at how biomedical science and engineering technology are integral to developing novel approaches to major problems, such as those associated with disease diagnosis and drug delivery. By covering a full range of materials processing and technology-related subjects, it shares timely information for biotechnologists, material scientists, biophysicists, chemists, bioengineers, nanotechnologists, and medical researchers.

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3D and Circuit Integration of MEMS Explore heterogeneous circuit integration and the packaging needed for practical applications of microsystemsMEMS and system integration are important building blocks for the “More-Than-Moore” paradigm described in the International Technology Roadmap for Semiconductors. And, in 3D and Circuit Integration of MEMS, distinguished editor Dr. Masayoshi Esashi delivers a comprehensive and systematic exploration of the technologies for microsystem packaging and heterogeneous integration. The book focuses on the silicon MEMS that have been used extensively and the technologies surrounding system integration.You’ll learn about topics as varied as bulk micromachining, surface micromachining, CMOS-MEMS, wafer interconnection, wafer bonding, and sealing. Highly relevant for researchers involved in microsystem technologies, the book is also ideal for anyone working in the microsystems industry. It demonstrates the key technologies that will assist researchers and professionals deal with current and future application bottlenecks.Readers will also benefit from the inclusion of:A thorough introduction to enhanced bulk micromachining on MIS process, including pressure sensor fabrication and the extension of MIS process for various advanced MEMS devicesAn exploration of epitaxial poly Si surface micromachining, including process condition of epi-poly Si, and MEMS devices using epi-poly SiPractical discussions of Poly SiGe surface micromachining, including SiGe deposition and LP CVD polycrystalline SiGeA concise treatment of heterogeneously integrated aluminum nitride MEMS resonators and filtersPerfect for materials scientists, electronics engineers, and electrical and mechanical engineers, 3D and Circuit Integration of MEMS will also earn a place in the libraries of semiconductor physicists seeking a one-stop reference for circuit integration and the practical application of microsystems.

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Solid State Development and Processing of Pharmaceutical Molecules A guide to the lastest industry principles for optimizing the production of solid state active pharmaceutical ingredients Solid State Development and Processing of Pharmaceutical Molecules is an authoritative guide that covers the entire pharmaceutical value chain. The authors—noted experts on the topic—examine the importance of the solid state form of chemical and biological drugs and review the development, production, quality control, formulation, and stability of medicines. The book explores the most recent trends in the digitization and automation of the pharmaceutical production processes that reflect the need for consistent high quality. It also includes information on relevant regulatory and intellectual property considerations. This resource is aimed at professionals in the pharmaceutical industry and offers an in-depth examination of the commercially relevant issues facing developers, producers and distributors of drug substances. This important book: Provides a guide for the effective development of solid drug forms Compares different characterization methods for solid state APIs Offers a resource for understanding efficient production methods for solid state forms of chemical and biological drugs Includes information on automation, process control, and machine learning as an integral part of the development and production workflows Covers in detail the regulatory and quality control aspects of drug development Written for medicinal chemists, pharmaceutical industry professionals, pharma engineers, solid state chemists, chemical engineers, Solid State Development and Processing of Pharmaceutical Molecules reviews information on the solid state of active pharmaceutical ingredients for their efficient development and production.

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Asymmetric Hydrogenation and Transfer Hydrogenation Discover the latest developments in homogeneous asymmetric (transfer) hydrogenation with this up-to-date resourceAsymmetric Hydrogenation and Transfer Hydrogenation delivers a current and cutting-edge investigation of homogenous asymmetric hydrogenation and transfer hydrogenation reactions of prochiral substrates by using organometallic catalysts (like ruthenium, rhodium, iridium, iron, and copper) and organic catalysts.Distinguished researchers and editors Virginie Ratovelomanana-Vidal and Phannarath Phansavath also offer readers a comprehensive walkthrough of substituted ketones through dynamic kinetic resolution, as well a presentation of the mechanisms and application of asymmetric hydrogenation reactions to the synthesis of biologically relevant compounds.The book comprehensively details its complex subject matter clearly and plainly and covers everything from catalyst development and reactions to mechanisms and applications in academia and industry. The papers included within come from many of the leading voices in their respective fields and represent the newest and best research available today.Compiled for researchers and private-industry chemists alike, Asymmetric Hydrogenation and Transfer Hydrogenation also discusses a wide variety of other topics like: A discussion of the development of chiral metal catalysts for asymmetric transfer hydrogenation Several examinations of asymmetric transfer hydrogenation of a variety of chemical groups, including ketones, aryl and heteroaryl ketones, substituted ketones, and heteroaromatic compounds, alkenes, and imines An exploration of the mechanism of asymmetric hydrogenation and continuous flow asymmetric hydrogenation A full and thorough treatment of the industrial applications of asymmetric hydrogenation Perfect for catalytic chemists, chemists working on or with organometallics, organic chemists, natural product chemists, pharmaceutical chemists, medicinal chemists, and industrial chemists, Asymmetric Hydrogenation and Transfer Hydrogenation also belongs on the bookshelves of research and university institutes and libraries who wish to expand their selection on a topic fundamental to organic synthesis.

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The know-how about reactivity, reaction mechanisms, thermodynamics and other basics in physical organic chemistry is the key for successful organic reactions. This textbook with its workbook presents comprehensively this knowledge to the student and to the researcher, too.

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A practice-oriented guide to assaying more than 100 of the most important enzymes, complete with the theoretical background and specific protocols for immediate use in the biochemical laboratory. Now expanded with a new section on metal ion determination.

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Photoinitiators A comprehensive text that covers everything from the processes and mechanisms to the reactions and industrial applications of photoinitiatorsPhotoinitiators offers a wide-ranging overview of existing photoinitiators and photoinitiating systems and their uses in ever-growing green technologies. The authors—noted experts on the topic—provide a concise review of the backgrounds in photopolymerization and photochemistry, explain the available structures, and examine the excited state properties, involved mechanisms, and structure, reactivity, and efficiency relationships. The text also contains information on the latest developments and trends in the design of novel tailor-made systems.The book explores the role of current systems in existing and emerging processes and applications. Comprehensive in scope, it covers polymerization of thick samples and in-shadow areas, polymerization under LEDs, NIR light induced thermal polymerization, photoinitiators for novel specific and improved properties, and much more. Written by an experienced and internationally renowned team of authors, this important book:Provides detailed information about excited state processes, mechanisms and design of efficient photoinitiator systemsDiscusses the performance of photoinitiators of polymerization by numerous examples of reactions and applicationIncludes information on industrial applicationsPresents a review of current developments and challengesOffers an introduction to the background information necessary to understand thefieldThe role played by photoinitiators in a variety of different polymerization reactionsWritten for polymer chemists, photochemists, and materials scientists, Photoinitiators will also earn a place in the libraries of photochemists seeking an authoritative, one-stop guide to the processes, mechanisms, and industrial applications of photoinitiators.

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Comprehensively teaches all of the fundamentals of fragrance chemistry Ernest Beaux, the perfumer who created Chanel No. 5, said, "One has to rely on chemists to find new aroma chemicals creating new, original notes. In perfumery, the future lies primarily in the hands of chemists." This book provides chemists and chemists-to-be with everything they need to know in order to create welcome new fragrances for the world to enjoy. It offers a simplified introduction into organic chemistry, including separation techniques and analytical methodologies; discusses the structure of perfume creation with respect to the many reactive ingredients in consumer products; and shows how to formulate effective and long-lasting scents. Fundamentals of Fragrance Chemistry starts by covering the structure of matter in order to show how its building blocks are held together. It continues with chapters that look at hydrocarbons and heteroatoms. A description of the three states of matter and how each can be converted into another is offered next, followed by coverage of separation and purification of materials. Other chapters examine acid/base reactions; oxidation and reduction reactions; perfume structure; the mechanism of olfaction; natural and synthetic fragrance ingredients; and much more. -Concentrates on aspects of organic chemistry, which are of particular importance to the fragrance industry -Offers non-chemists a simplified yet complete introduction to organic chemistry?from separation techniques and analytical methodologies to the structure of perfume creation -Provides innovative perfumers with a framework to formulate stable fragrances from the myriad of active ingredients available -Looks at future trends in the industry and addresses concerns about sustainability and quality management Fundamentals of Fragrance Chemistry is an ideal resource for students who are new to the subject, as well as for chemists and perfumers already working in this fragrant field of science.

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Macromolecular Engineering Complete and Thorough Resource on Macromolecular Engineering for Researchers and Industry Professionals This book covers the entire field of macromolecular engineering, from design and preparation of well-defined macromolecules, to precise characterization, all the way to optimization for specific functions and applications. It provides background information, comparative advantages and limitations, the most recent advances of numerous synthetic approaches, characterization techniques, and potential applications. The second edition has been completely updated and edited by a world-class team of editors led by K. Matyjaszewski. Sample topics covered within the work include: Synthetic tools to precisely control various aspects of macromolecular structure including chain composition, microstructure, functionality, and topology Modern characterization techniques at the molecular and macroscopic level for various properties of well-defined (co)polymers in solution, bulk and at surfaces The correlation of molecular structure with macroscopic properties additionally affected by processing Self-healing polymers, renewable resources, photopolymerization, click chemistry, organocatalysis, hierarchical self-assembly, nanocarbon, and ionic liquids Polymer chemists and engineers, materials scientists, and professionals in the plastics and pharmaceutical industries will be able to use Macromolecular Engineering as a completely comprehensive reference work to understand macromolecular engineering and its many practical applications.

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Der "kleine" Atkins ist ideal für Bachelor-Studierende der Chemie und Studierende anderer Naturwissenschaften sowie der Ingenieurwissenschaften: das Buch führt ein in die Grundlagen der Physikalischen Chemie, die besonders hohe Anforderungen an die Studentinnen und Studenten stellt. Das erstmals auf Deutsch vorliegende Arbeitsbuch zur 5. Auflage des "kleinen" Atkins ermöglicht die eigenständige Kontrolle des Lernerfolgs dank der ausführlich durchgerechneten Lösungen der mehr als 800 Aufgaben aus dem Lehrbuch. Auch im attraktiven Deluxe-Set mit dem Lehrbuch erhältlich!

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Based on the WHO's Anatomical Therapeutical Chemical (ATC) classification system, virtually all marketed therapeutics are covered here in 48 topical sections. Each section contains a general introduction to the therapeutic class, current developments, and challenges, followed by a systematic listing of all important marketed products. For each therapeutic, up-to-date information on compound structure, mechanism, formulation, clinical use, time on market, and production methods is provided, complete with refrences to the scientific and patent literature. With ULLMANN's being one of the most renowned and trusted references in the field of industrial chemistry, this selection of ULLMANN's articles is an indispensable guide for every professional in the pharmaceutical and medical sector and provides reliable data on more than 3,500 pharmaceutical products marketed up to 2021.

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Addition Reactions with Unsaturated Hydrocarbons Provides comprehensive coverage of the atom-economic approach to functionalized molecules using unsaturated hydrocarbons as starting materials Unsaturated hydrocarbons have emerged as an important class of fundamental starting materials in organic synthesis. Synthetic methodologies incorporating unsaturated hydrocarbons continue to expand due to their numerous applications in the synthesis of a vast array of chemicals. Addition Reactions with Unsaturated Hydrocarbons presents an up-to-date overview of modern methods that utilize reactions of unsaturated hydrocarbons as building blocks of organic synthesis, covering the conceptual and practical knowledge required for designing atom-efficient reactions to synthesize functionalized molecules. This authoritative volume discusses homo-dimerization and cross-dimerization of alkynes and/or alkenes, synthesis of carbonyl compounds from the hydration of alkynes, cycloadditions of alkynes and alkenes for the synthesis of carbocycles and heterocycles, double functionalization of alkynes and alkenes by addition reactions of element-element bonds, and more. Summarizes the most recent developments in the reactions of unsaturated hydrocarbons Features more than 600 schemes describing typical reactions starting from unsaturated hydrocarbons Covers topics such as alkynylated reactions, addition and cycloaddition reactions of alkynes and alkenes, and carbonylation of alkynes and alkenes with carbon monoxide Includes examples of synthesis procedures of natural products involving alkyne transformation With comprehensive coverage of important reactions of unsaturated hydrocarbons, Addition Reactions with Unsaturated Hydrocarbons is a valuable resource for organic chemists, pharmaceutical chemists, and biochemists in both academia and industry as well as an excellent reference text for graduate students in relevant areas of chemistry.

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The basic working knowledge for the practicing control engineer in industry, offered here as a handy deluxe edition comprising two volumes each devoted to methods and practical problems. Focusing on the practical implementation, the methods volume provides readers with rapid access to process modelling and control, while including the theoretical background necessary. Throughout, the essential knowledge is built up from chapter to chapter, starting with laying the foundations in plant instrumentation and control. Modelling abilities are then developed by starting from simple time-loop algorithms and passing on to discrete methods, Laplace transforms, automata and fuzzy logic. In the end, readers have the means to design simple controllers on the basis of their own models, and to use more detailed models to test them. With its clarity and simplicity of presentation, and illustrated by more than 200 diagrams, the volume supports self-study and teaches readers how to apply the appropriate method for the application required, and how to handle problems in process control. Bridging theory and practice, the second volume contains over 200 practical exercises and their solutions to develop the problem-solving abilities of process engineers. The problems were developed by the author during his many years of teaching at university and are kept brief, taken from the fields of instrumentation, modeling, plant control, control strategy design and stability of control. The algorithm flows and codes, which are mostly based on MATLAB®, are given in many cases and allow for easy translation into applications. With a clarity and simplicity of presentation, the two volumes are similarly structured for easy orientation.

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A comprehensive source of information about modern drying technologies that uniquely focus on the processing of pharmaceuticals and biologicals Drying technologies are an indispensable production step in the pharmaceutical industry and the knowledge of drying technologies and applications is absolutely essential for current drug product development. This book focuses on the application of various drying technologies to the processing of pharmaceuticals and biologicals. It offers a complete overview of innovative as well as standard drying technologies, and addresses the issues of why drying is required and what the critical considerations are for implementing this process operation during drug product development. Drying Technologies for Biotechnology and Pharmaceutical Applications discusses the state-of-the-art of established drying technologies like freeze- and spray- drying and highlights limitations that need to be overcome to achieve the future state of pharmaceutical manufacturing. The book also describes promising next generation drying technologies, which are currently used in fields outside of pharmaceuticals, and how they can be implemented and adapted for future use in the pharmaceutical industry. In addition, it deals with the generation of synergistic effects (e.g. by applying process analytical technology) and provides an outlook toward future developments. -Presents a full technical overview of well established standard drying methods alongside various other drying technologies, possible improvements, limitations, synergies, and future directions -Outlines different drying technologies from an application-oriented point of view and with consideration of real world challenges in the field of drug product development -Edited by renowned experts from the pharmaceutical industry and assembled by leading experts from industry and academia Drying Technologies for Biotechnology and Pharmaceutical Applications is an important book for pharma engineers, process engineers, chemical engineers, and others who work in related industries.

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The book focuses on advanced characterization methods for thin-film solar cells that have proven their relevance both for academic and corporate photovoltaic research and development. After an introduction to thin-film photovoltaics, highly experienced experts report on device and materials characterization methods such as electroluminescence analysis, capacitance spectroscopy, and various microscopy methods. In the final part of the book simulation techniques are presented which are used for ab-initio calculations of relevant semiconductors and for device simulations in 1D, 2D and 3D. Building on a proven concept, this new edition also covers thermography, transient optoelectronic methods, and absorption and photocurrent spectroscopy.

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This fourth volume of the landmark handbook focuses on the design, testing, and thermal management of 3D-integrated circuits, both from a technological and materials science perspective. Edited and authored by key contributors from top research institutions and high-tech companies, the first part of the book provides an overview of the latest developments in 3D chip design, including challenges and opportunities. The second part focuses on the test methods used to assess the quality and reliability of the 3D-integrated circuits, while the third and final part deals with thermal management and advanced cooling technologies and their integration.

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This ready reference not only presents the hot and emerging topic of modern flow chemistry, it is also unique in illustrating the important connection to sustainable chemistry. Focusing on more sustainable methods and applications, the text extensively covers every important field from reaction time optimization to waste minimization, and from safety improvements to microwave applications. In addition, green metrics are presented as a key aspect of the book, helping readers to evaluate the efficiency of flow technologies and their impact on the overall efficiency of a chemical process. An invaluable handbook for every chemist working in the laboratory, whether in academia or industry.

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The book describes the morphological, physical and chemical properties of aerosols from various natural and anthropogenic sources to help the reader better understand the direct role of aerosol particles in scattering and absorbing short- and long-wave radiation.

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Combining different perspectives from materials science, engineering, and computer science, this reference provides a unified view of the various aspects necessary for the successful realization of intelligent systems. The editors and authors are from academia and research institutions with close ties to industry, and are thus able to offer first-hand information here. They adopt a unique, three-tiered approach such that readers can gain basic, intermediate, and advanced topical knowledge. The technology section of the book is divided into chapters covering the basics of sensor integration in materials, the challenges associated with this approach, data processing, evaluation, and validation, as well as methods for achieving an autonomous energy supply. The applications part then goes on to showcase typical scenarios where material-integrated intelligent systems are already in use, such as for structural health monitoring and smart textiles.

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Originally based on a graduate course taught by the author, this true classic has once again been extensively updated to incorporate key new findings in biological signaling. With over half of the content re-written, plus 70 brand new and 50 revised figures, this is the most up-to-date textbook on signaling available anywhere. Thanks to its clear structure, hundreds of illustrative drawings, as well as chapter introductions and newly added study questions, this text excels as a companion for a course on biological signaling, and equally as an introductory reference to the field for students and researchers. Generations of students and junior researchers have relied on "the Krauss" to find their way through the bewildering complexity of biological signaling pathways.

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A review of the interdisciplinary field of synthetic biology, from genome design to spatial engineering. Written by an international panel of experts, Synthetic Biology draws from various areas of research in biology and engineering and explores the current applications to provide an authoritative overview of this burgeoning field. The text reviews the synthesis of DNA and genome engineering and offers a discussion of the parts and devices that control protein expression and activity. The authors include information on the devices that support spatial engineering, RNA switches and explore the early applications of synthetic biology in protein synthesis, generation of pathway libraries, and immunotherapy. Filled with the most recent research, compelling discussions, and unique perspectives, Synthetic Biology offers an important resource for understanding how this new branch of science can improve on applications for industry or biological research.

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Now in it's 3rd Edition, Industrial Catalysis offers all relevant information on catalytic processes in industry, including many recent examples. Perfectly suited for self-study, it is the ideal companion for scientists who want to get into the field or refresh existing knowledge.The updated edition covers the full range of industrial aspects, from catalyst development and testing to process examples and catalyst recycling. The book is characterized by its practical relevance, expressed by a selection of over 40 examples of catalytic processes in industry. In addition, new chapters on catalytic processes with renewable materials and polymerization catalysis have been included. Existing chapters have been carefully revised and supported by new subchapters, for example, on metathesis reactions, refinery processes, petrochemistry and new reactor concepts. "I found the book accesible, readable and interesting - both as a refresher and as an introduction to new topics - and a convenient first reference on current industrial catalytic practise and processes." Excerpt from a book review for the second edition by P. C. H. Mitchell, Applied Organometallic Chemistry (2007)

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Crystallization is a natural occurring process but also a process abundantly used in the industry. Crystallization can occur from a solution, from the melt or via deposition of material from the gas phase (desublimation). Crystals distinguish themself from liquids, gases and amorphous substances by the long-range order of its building blocks that entail the crystals to be formed of well-defined faces, and give rise to a large number of properties of the solid. Crystallization is used at some stage in nearly all process industries as a method of production, purification or recovery of solid materials. Crystallization is practiced on all scales: from the isolation of the first milligrams of a newly synthesized substance in the research laboratory to isolating products on the mulit-million tonne scale in industry. The book describes the breadth of crystallization operations, from isolation from a reaction broth to purification and finally to tailoring product properties. In the first section of the book, the basic mechanisms - nucleation, growth, attrition and agglomeration are introduced. It ensures an understanding of supersaturation, the driving force of crystallization. Furthermore, the solubility of the substance and its dependences on process conditions and the various techniques of crystallization and their possibilities and limitations are discussed. Last but not least, the first part includes an intensive treatment of polymorphism . The second part builds on the basics, exploring how crystallization processes can be developed, either batch-wise or continuous, from solution or from the melt. A discussion of the purification during crystallization serves as a link between the two sections, where practical aspects and an insight using theoretical concepts are combined. Mixing and its influence on the crystallization as well as the mutual interference of down-stream processes with the crystallization are also treated. Finally, techniques to characterize the crop are discussed. The third part of the book is dedicated to accounts of actual developments and of carried-out crystallizations. Typical pitfalls and strategies to avoid these as well as the design of robust processes are presented.

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Authored by 40 of the most prominent and renowned international scientists from academia, industry, institutions and government, this handbook explores mature, evolving technologies for a clean, economically viable alternative to non-renewable energy. In so doing, it includes how hydrogen can be safely produced, stored, transported and utilized, while also covering such broader topics as the environmental impact, education and regulatory developments.

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This manageably sized dictionary covers theory, experiment, industrial practice and applications for nanotechnology, colloid, and interface science, as well as much of what is now termed materials science. The comprehensive information is presented in several sections and formats: dictionary of terms, classification tables on colloid and nanomaterial types, and sub-term glossaries for specific phenomena, properties and methods. It offers both newly-coined as well as older terms whose meanings have changed, providing acronyms, synonyms, famous names, selected abbreviations, and cross-references. It also contains a historical overview, units and symbols, and a separate literature section for further reading and following-up on specific topics. An authoritative reference, vital for unhindered communication and knowledge transfer in this fast-growing and broadly interdisciplinary field.

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This second edition has 20% more scope, with four completely new chapters and eight existing ones completely revised to include more modeling, more industrial examples, new coating types, and new medical applications. Combining theory and practice from design to application, the monograph continues to provide a state-of-the-art treatise on plasma spray technology, beginning with the principles and techniques. Successive chapters treat the three important stages of energy transfer from the plasma to the surface, with modeling, depositing, testing and applying ceramic and metallic coatings covered in the shape of industrial problem solution examples. Concluding with quality control and a new section on biomedical issues and opportunities, the book offers pertinent knowledge for materials scientists, engineers, biologists and medical researchers alike.

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Bad experiences with construction quality, the energy crises of 1973 and 1979, complaints about "sick buildings", thermal, acoustical, visual and olfactory discomfort, the need for good air quality, the move towards energy efficiency, decarbonization and sustainability - all these have accelerated the development of a discipline that, for a long time, was hardly more than an academic exercise: building physics. The discipline embraces domains such as heat and mass transfer, building acoustics, lighting, indoor environmental quality, energy efficiency, and, in some countries, fire safety. Through the application of physical knowledge and its combination with information coming from other disciplines, building physics helps to under-stand the physical phenomena governing building parts, building envelope, whole building and built environment performance - called urban physics. Today, building physics has be-come a key player on the road to highly performing new buildings and renovations. The first book deals with heat, air and moisture transport in building parts or assemblies and whole buildings with emphasis on the building engineering applications. The second book on applied building physics focuses on the question of what a well-balanced building performance consists of. Here, the environmental loads on buildings are explained - i.e. all those parameters that describe the external and internal environmental conditions, with an emphasis on practical implementation. Then follows a comprehensive presentation of those performance requirements that are important at the whole-building level, mainly considering thermal, acoustic, visual and olfactory comfort, indoor air quality, energy consumption, durability, economy and sustainability. This is followed by an in-depth discussion of the requirements regarding thermal, air and moisture behaviour as well as the measured variables at the level of the building construction and components. The analyses and calculations described in this book result in sustainable buildings made of functional and durable building constructions, with comfortable and healthy indoor climate. Compared to the previous editions, both books have been expanded to include the physical determination of the thermal conductivity of materials, together with an in-depth discussion of all the effects of thicker insulation layers. Additional information has been added on wind pressure and the evaluation of condensation inside the building components, while a new chapter on material properties has been included. Both volumes, including the figures, have been revised and restructured where necessary.

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This volume elucidates the design criteria and principles for steel structures under seismic loads according to Eurocode 8-1. Worked Examples illustrate the application of the design rules. Two case studies serve as best-practice samples.

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