Search results for ""spectrum""

A Closer Look at Kinase Inhibition opens with a discussion on the roles of various tyrosine kinases inhibitors and molecular mechanisms of acquired resistance to tyrosine kinase inhibitor drugs therapy in colon-rectal cancer. The authors summarize host cell and viral protein kinases, the progress in their use, and the repurposing of approved kinase inhibitors as broad-spectrum antivirals. The key kinases, namely CLK1, DYRK1A, CDK5, GSK3 and CK1, are analyzed as data indicate that targeting these proteins may have therapeutic promise against Alzheimer's disease.

Read more less

The intervention-spectrum for psychiatric disorders is very broad and its useful to be able to see advances in the field in one place. This multi-authored book outlines the cutting-edge contents of psychiatric therapeutics and will prove useful for both clinicians and researchers. Published under the banner of Indian Psychiatric Society. Explores the different facets and interfaces of varied psychiatric therapeutics. Brings together new and innovative therapeutic strategies along with the newer versions of older established treatment strategies.

Read more less

This publication spans more than 40 years of artistic work by the painter Henning Bertram (b. 1962). Many in the Rhineland know him through his large-scale charcoal drawings of seemingly archaic fragments of architecture. This book provides for the first-time insight into Bertram’s early work and the spectrum of his artistic career— an unremittingly explorative path, switching between the abstract and the figurative, culminating in a surprising corporeality evident in his current work. Text in English and German.

Read more less

This ground-breaking book provides the first detailed clinical analysis of the various manifestations of catatonia, shutdown and breakdown in autistic individuals, with a new assessment framework (ACE-S) and guidance on intervention and management strategies using a psycho-ecological approach. Based on Dr Amitta Shah's lifetime of clinical experience in Autism Spectrum Disorders, and her research in collaboration with Dr Lorna Wing, this much needed book will be a valuable resource for professionals, autistic individuals and their families and carers.

Read more less

The TASCHEN bookstand brings your collection out from the confines of your bookshelves, and back to its rightful place on center-stage.The three sizes of medium, large, and extra-large allow for the secure and stylish display of almost our entire spectrum of titles, except for our gargantuan SUMOs. Also reflecting the variety within our editions, three eye-catching colors radiant pink, crystal green, and urban grey provide a fitting foundation to display TASCHEN's big, bright, and bold back catalog.

Read more less

This volume contains over 200 enjoyable and stimulating activities and exercises ranging over the entire gamut of social and emotional development, and is applicable to anyone, regardless of diagnosis, but will be particularly valuable for those on the autism spectrum. Activities can be undertaken independently, or with a teacher or therapist, and a full schema for the evaluation of progress and objectives is included. A companion website, free to purchasers provides a wealth of further information and support.

Read more less

This volume takes political, social and cultural approaches to the study of the Seljuq dynasty, shedding new light on a variety of subjects. The various chapters cover geographical spectrum, from Central Asia and Persia to Iraq, Syria and Anatolia, and address questions such as the ideological foundations and ritual expressions of Seljuq power, the mutual attitudes of the learned classes and the Seljuq state, the organization of space, and the relationship between nomads and the settled peoples.

Read more less

The creative literature that evolved from the Holocaust constitutes an unprecedented encounter between art and life. Those who wrote about the Holocaust were forced to extend the limits of their imaginations to encompass unspeakably violent extremes of human behavior. The result, as Ezrahi shows in By Words Alone, is a body of literature that transcends national and cultural boundaries and shares a spectrum of attitudes toward the concentration camps and the world beyond, toward the past and the future.

Read more less

Every day is filled with opportunities to wonder . . . what if? In this charming book of big questions for little readers, New York Times bestselling creator Renata Liwska explores scenarios that span the spectrum from silly to serious, gently examining both the anxieties and curiosities of everyday life. Wondering what might happen helps expand our imaginations, whether the options are humorous or thought-provoking - or both! So: what if . . . you turned the page?

Read more less

In what sense is the U.S. Constitution binding on contemporary and future generations of Americans? This question was at stake in the fights over the nominations of Robert Bork and Clarence Thomas to the Supreme Court and in the extensive debate over 'original intent' carried on by Attorney General Edwin Meese and Chief Justice William Rehnquist, among others. This collection brings together ten leading philosophers, legal scholars, and political scientists representing a spectrum of opinions.

Read more less

All About PDA follows in the best-selling footsteps of Kathy Hoopmann''s All Cats are on the Autism Spectrum and All Dogs have ADHD. Through engaging text and full-colour photographs, this book shows how PDAers see and experience the world and highlights the unique characteristics that make them special.A perfect introduction to PDA for those recently diagnosed, as well as their families, friends, and the people who work with them!

Read more less

Adults are invited to express their sense of color and creativity in this book of lovingly detailed drawings of the American West's Victorian-era buildings. In pen and ink, artist Shirley Salzman depicts a spectrum of styles within the period of Queen Victoria’s reign from 1837 to 1901. The black-and-white sketches are printed on high-quality paper in a fold-out-flat format and can be framed as they are or imaginatively embellished.

Read more less

This is the most up-to-date book yet published on pathology of the head and neck. Its contents have been divided into ten chapters, devoted to the spectrum of precursor and neoplastic lesions of the squamous epithelium; the nasal cavities and paranasal sinuses; oral cavity, maxillofacial skeleton and teeth; salivary glands, nasopharynx and Waldeyer`s ring; larynx and hypopharynx, ear and temporal bone; neck and neck dissection, as well as eye and ocular adnexa.

Read more less

A one-stop compendium for parents of children with autism.The most recent studies estimate that 1 in 68 children in America are on the autism spectrum. For the parents and families of these children, having support is vital. But the search for the right information can be difficult, and it may be even harder to find the time for the research that is needed. The Parent’s Autism Sourcebook brings that information to you, offering families of children with autism a full range of up-to-date resources on diagnoses, doctors, organizations, and much more.Whether you are concerned about finding the right school, possible treatment options, methods for social interaction, or are just looking for the support of other parents of children with autism, this book can help you find what you need. The resources gathered from across the nation in this comprehensive sourcebook include information on:Evaluation and screening methodsSpecialized doctors and clinicsSchools and social groupsPotential treatments and interventionsLegal services and consultationAnd moreRaising a child on the autism spectrum can present unique challenges for parents. Finding the resources and support they need shouldn’t be one of them. The Parent’s Autism Sourcebook will help families everywhere.

Read more less

This Handbook is an essential reference and a guide to the rapidly expanding field of Geographic Information Science. Designed for students and researchers who want an in-depth treatment of the subject, including background information Comprises around 40 substantial essays, each written by a recognized expert in a particular area Covers the full spectrum of research in GIS Surveys the increasing number of applications of GIS Predicts how GIS is likely to evolve in the near future

Read more less

Provides a practical introduction written by engineers from the leading wireless LAN manufacturers Each chapter brings the reader up-to-date with the latest in LAN technology from such companies as 3com, Alcatel, Ericsson, Intermec, Mobilian, Cisco Systems, Texas Instruments, Time Domain Corp., and Network Associates Provides detailed information for anyone who wants to learn about, implement, or invest in wireless LAN technology Features chapters on security, Bluetooth, spectrum allocation, QoS, ultra-wideband wireless, key standards, and more

Read more less

As the number of children diagnosed with autism spectrum disorders grows each year, new discoveries and controversies arise. Andrew Wakefield explores many of these in his thorough investigation of the recent trial case of the “Arizona 5,” which destroyed an Arizona family. Two parents, with five children on the spectrum, were accused of Münchausen syndrome by proxy—a rare form of child abuse—and were ganged up on by physicians, child protective services, and the courts, who alleged that the parents fabricated medical symptoms in all five children. However, Wakefield now presents ample evidence that was disregarded and which would have proven the parents’ innocence. Families affected by autism suffer great hardship and prejudice, particularly as they navigate the uncertain waters of diagnosis, treatment, and education. The shocking story of the Arizona 5 family delves into the tremendous challenges some parents have to face, especially if their views on how to treat the syndrome don’t align with the medical world’s standards. Wakefield also includes numerous studies and research trials that support the controversial yet significant roles that vaccines and diet play in autism, factors many medical professionals wrongfully dismiss.

Read more less

Going to college can be a daunting prospect for any young person, but for teenagers on the autism spectrum this is especially true. This book describes the unique needs that ASD students entering further or higher education are likely to have. The author identifies the key skill-sets they will need to develop in order to be successful in college and in life, and shows how they can be helped to develop these. She outlines the skills required for success in further and higher education in relation to the strengths and weaknesses of individuals with ASDs, and explains how those weaknesses can be ameliorated to enable success at college. Describing the unique accommodations and support that students with ASD will need, and the skills for which they will need particular help, she provides effective intervention strategies that can be implemented throughout the period leading up to college entrance. This book is essential reading for psychologists, special educators, educational therapists, high school teachers/career counselors, and other professionals supporting high school and college students on the autism spectrum. Parents of such students will also benefit from the ideas presented in this book.

Read more less

This book examines real life reflections on Autism Spectrum Disorders (ASD), current practices and issues related to assessing, instructing and life-long planning for individuals with autism and developmental disabilities. School systems, mental health facilities, and society are being challenged to deal effectively with the growing number of people with autism and developmental disabilities. This is partly due to the inclusive philosophy of educating, training and treating individuals. This book provides regular, special educators, mental health professionals, clinicians and parents with information on best practices and research based findings related to: identification, characteristics, diagnosis; special, general, early and post-secondary education; and quality of life concerns. The book's chapters are topical, comprehensive and diverse. Chapters on assessment examine the emerging field of infant mental health, testing protocols, barriers to diagnosing diverse students, and recent developments in the diagnosing and assessment of autism spectrum disorders i.e. genetic testing, home movies and robots. A number of chapters on instructional aspects delineate curriculum innovations, procedures to implement social skills, assistive technology use and planning for postsecondary education. Life long planning, provides unique content on self-determination, social competence, sibling aspects, and employment and retirement considerations.

Read more less

Against the background of Christian-determined visions of the future, decision-making processes represent a form of literary appropriation and shaping of the future. The anthology poses the question of the relationship between decision-making processes and drafts of the future in pre-modern narration: what is the significance of telling decisions against the background of 'closed' conceptions of the future? The collected contributions cover a broad spectrum of pre-modern storytelling and for the first time measure the scope for optionality in the literature of the Middle Ages and the early modern period.

Read more less

Going to the beach is exciting. But it can also be busy. And loud. Sand can feel hot or itchy or sticky . . . . and it gets everywhere! In This Beach Is Loud!, a sensitive boy gets overwhelmed by all the sights, sounds, and sensations at the beach. Luckily, this kiddo’s dad has a trick up his sleeve to help his son face these unexpected obstacles. Combining accessible storytelling and playful design, This Beach Is Loud! gently offers practical advice for coping with new experiences to sensitive children on and off the autism spectrum.

Read more less

This Atlas provides cutting-edge information on uveitis, which represents a major achievement in clinical studies on uveitis. It includes more than three thousand imaging photos of uveitis patients, showing the disease’s complete profile and the spectrum of variations commonly encountered. Numerous therapeutic regimens are also presented, each of which is designed for a specific form of uveitis. The Atlas also incorporates the latest advances in uveitis studies, making it a unique and valuable resource for a broad readership, including ophthalmologists, postgraduate students, medical students and doctors in ophthalmology.

Read more less

Friendship, even for the most able, requires hard work, and the odds are heavily stacked against those with autism spectrum conditions. Designed for younger children, typically between the ages of two and eight, this comprehensive set of enjoyable activities emphasizes foundation skills such as social referencing, regulating behavior, conversational reciprocity and synchronized actions. The authors include many objectives to plan and evaluate a child's progress, each one related to a specific exercise. Suitable for parental use, the manual is also designed for easy implementation in schools and in therapeutic settings.

Read more less

From a preeminent researcher, this book looks at the key role of joint attention in both typical and atypical development. Peter C. Mundy shows that no other symptom dimension is more strongly linked to early identification and treatment of autism spectrum disorder (ASD). He synthesizes a wealth of knowledge on how joint attention develops, its neurocognitive underpinnings, and how it helps to explain the learning, language, and social-cognitive features of ASD across the lifespan. Clinical implications are explored, including reviews of cutting-edge diagnostic methods and targeted treatment approaches.

Read more less

This book focuses on various facets of stainless steel, including processing, component design, properties, fabrication, and applications. It covers a broad spectrum of topics spanning the entire life cycle of stainless steel, from alloy design and characterization to engineering design, fabrication, mechanical properties, corrosion, quality assurance of components, in-service performance assessment, and life prediction and failure analysis of materials and components. Exploring contemporary developments in stainless steels, the text discusses component design, modeling and structural integrity, manufacturing technology, property evaluation, alloy development and applications, nondestructive evaluation methods, and corrosion and surface modification.

Read more less

This book results from the 7th ICPMG meeting in Zurich 2010 and covers a broad range of aspects of physical modelling in geotechnics, linking across to other modelling techniques to consider the entire spectrum required in providing innovative geotechnical engineering solutions.Topics presented at the conference:Soil â Structure â Interaction; Natural Hazards; Earthquake Engineering: Soft Soil Engineering; New Geotechnical Physical; Modelling Facilities; Advanced Experimental Techniques; Comparisons between Physical and Numerical ModellingSpecific Topics: Offshore Engineering; Ground Improvement and Foundations; Tunnelling, Excavations and Retaining Structures; Dams and slopes; Process Modelling; Goenvironmental Modelling; Education

Read more less

G. J. Barker-Benfield documents the emergence of the culture of sensibility that transformed British society of the eighteenth century. His account focuses on the rise of new moral and spiritual values and the struggle to redefine the group identities of men and women. Drawing on the full spectrum of eighteenth-century thought from Adam Smith to John Locke, from the Earl of Shaftesberry to Dr. George Cheyne, and especially Mary Wollstonecraft, Barker-Benfield offers an innovative and compelling way to understand how Britain entered the modern age.

Read more less

The charge of "Ressentiment" can in today's world - less from traditionally conservative quarters than from the neo-positivist discourses of particular forms of liberalism - be used to undermine the argumentative credibility of political opponents, dissidents and those who call for greater "justice". The essays in this volume draw on the broad spectrum of cultural discourse on "Ressentiment", both in historical and contemporary contexts. Starting with its conceptual genesis, the essays also show contemporary nuances of "Ressentiment" as well as its influence on literary and philosophical discourse in the 20th century.

Read more less

"Behold" is Nicki Jackowska's seventh book of poetry. The title poem vividly evokes the history of the Holocaust with precise particulars and mundane details. Her European consciousness and working-class English roots give her writing an extraordinary spectrum of awareness. Many of the poems are akin to dramatic monologues, moving from a Lewes garden party to characters in a Brighton Terrace and thence to Krakuw. John Berger writes of the collection that 'Its grief has penetrated its syntax, and when there's that kind of penetration - it changes the reader's breathing.'

Read more less

Written by an international team of contributors under the guidance of a distinguished editor, this book summarizes key techniques and their applications. The various chapters cover the spectrum of scales in modelling methodologies, including electronic structure calculations, mesoscale and continuum modelling. The book discusses dislocation behaviour and plasticity as well as the modelling of structural materials such as metals, polymers and ceramics. Multiscale materials modelling will be a valuable reference for both the modelling community and those in industry wanting to know more about how multiscale materials modelling can help optimise product and process design.

Read more less

What is the connection between autism and addiction? Why are individuals with autism more likely to develop a substance use disorder than the general population?Until recently, substance use disorder (SUD) was considered rare among those with autism spectrum disorder (ASD). This book brings together current research and personal accounts from individuals with autism and their supports. It explores why addiction is more common among individuals with ASD and investigates how addiction and autism affect one another. The authors also provide strategies for supporting people with both ASD and SUD.

Read more less

This title offers a fresh take on the craft of woodburning by focusing on the drawing, lettering and design elements that will add dimension and composition to any pyrography project. Pompano shares 5 tips on how to create a vast variety of dimension, shade and texture with your woodburner and how to develop your drawing skills for use in pyrography. The patterns cover a wide spectrum of themes including; harvest, wildlife, seaside and much more. The book includes two practice exercises, one step-by-step project and close-up instruction on lettering.

Read more less

Bold and beautiful, this volume presents hundreds of film stills from the Pixar archives in a glorious spectrum of color. Starting with bright white images and seamlessly flowing through the colors of the rainbow, it becomes crystal clear how each frame tells a story. Bound into a gorgeous volume, The Color of Pixar encapsulates everything there is to love about the studio: the attention to detail, the playful characters, and the sheer scope of their work in over 20 years of iconic feature films.Copyright ©2017 Disney Enterprises, Inc. and Pixar. All rights reserved.

Read more less

This book discusses a spectrum of approaches to designing the food-energy-water nexus at different spatial-urban scales. The book offers a framework for working on the FEW-nexus in a design-led context and integrates the design of urban neighbourhoods and regions with methodologies how to simultaneously engaging residents and stakeholders and evaluating the propositions in a FEW-print, measuring the environmental impact of the different designs. The examples are derived from on the ground practices in Sydney, Tokyo, Detroit, Amsterdam and Belfast.

Read more less

Johnny is different. He is never exactly on time, he can't seem to stick to a routine and he often speaks in cryptic idioms. Johnny is neurotypical, but that's OK.A picture book with a difference, Why Johnny Doesn't Flap turns the tables on common depictions of neurological difference by drolly revealing how people who are not on the autistic spectrum are perceived by those who are. The autistic narrator's bafflement at his neurotypical friend's quirks shows that 'normal' is simply a matter of perspective.

Read more less

This handbook details the nursing care of patients undergoing oral and maxillofacial surgery. It deals with diseases, disorders and injuries of the mouth, jaw and face and provides information on the full spectrum of patient care from pre-admission to discharge planning. It is jointly written by nurses and consultants in the area of maxillofacial surgery, and combines elements of nursing care with medical and surgical information. It provides an attractive alternative to the heavier medical tomes that nurses have come to rely upon.

Read more less

While freedom of speech has been guaranteed us for centuries, the First Amendment as we know it today is largely a creation of the past 80 years. "Eternally Vigilant" brings together a group of distinguished legal scholars to reflect boldly on its past, its present shape, and what forms our understanding of it might take in the future. The result is a unique volume spanning the entire spectrum of First Amendment issues, from its philosophical underpinnings to specific issues like campaign regulation, obscenity and the new media.

Read more less

Covering the entire spectrum of medical gases, this ready reference offers a comprehensive overview of production, medical gas equipment, medical gas verification, and medical gas safety standards. With a clear focus throughout on safety, the text recommends environmentally responsible manufacturing practices during each step of the process: manufacture, storage, transport, distribution, and in applications. It also discusses standards and regulations, in particular those of the European Union.An essential guide for researchers and professionals whose work includes the manufacture, handling, or use of medical gases.

Read more less

Simple Studies for Beginner Brass is a comprehensive course for the early stages of brass playing. The 38 short studies - all of them newly composed by John Miller - are arranged progressively, and each one poses a fresh technical challenge. The collection as a whole covers the entire spectrum of basic technique, while being coupled with a great deal of musical interest. An appendix contains a selection of scales and arpeggios. This book is suitable for any brass player who reads from the treble clef.

Read more less

This collection of primary, secondary, and visual sources for the Western Civilization survey course provides a broad introduction to the materials historians use, the interpretations historians make, and hundreds of years of Western civilization. Its broad selection of documents, photographs, maps, and charts, and its full array of accompanying commentaries--drawn from a balanced spectrum of perspectives and approaches--offer valuable insight into the work of historians and provide the context that helps students understand the texts' full historical significance.

Read more less

The massive convergence of information about cavernous malformations has been synthesized in this volume by experts in the field of pathology, neuroradiology and neurosurgery. Cavernous Malformations represents state–of–the–art knowledge about this lesion and the spectrum of opinion about its nature, clinical behavior and management strategies. Highlights of Cavernous Malformations: Definition and pathologic features Epidemiology Diagnostic imaging Epilepsy Hemorrhage Conservative management Surgical intervention Microsurgical treatments Spinal cavernous malformations Pediatrics Radiotherapy (Distributed by Thieme for the American Association of Neurological Surgeons)

Read more less

A practical introduction on today's challenge of controlling and managing the water resources used by and affected by cities and urbanized communities. The book offers an integrated engineering approach, covering the spectrum of urban watershed management, urban hydraulic systems, and overall stormwater management. Each chapter concludes with helpful problems. Solutions Manual available to qualified professors and instructors upon request. Introduces the reader to two popular, non-proprietary computer-modeling pro-grams: HEC-HMS (U.S. Army Corps of Engineers) and SWMM (U.S EPA).

Read more less

Fundamentals of Structural Analysis offers a comprehensive and well-integrated presentation of the foundational principles of structural analysis. It presents a rigorous treatment of the underlying theory and a broad spectrum of example problems to illustrate practical applications. The book is richly illustrated with a balance between realistic representations of actual structures and the idealized sketches customarily used in engineering practice. There is a large selection of problems that can be assigned by the instructor that range in difficulty from simple to challenging.

Read more less

Denys Johnson-Davies brings together this remarkable overview of the work of several generations of Egypt's leading short story writers. This selection of some fifty stories represents not only a cross-section through time but also a spectrum of styles, and includes works by Teymour, Hakki, Gohar, and Mahfouz and later writers such as Mohamed El-Bisatie, Said el-Kafrawi, Bahaa Taher, and Radwa Ashour, as well as new young writers of today like Hamdy El-Gazzar, Mansoura Ez Eldin, and Youssef Rakha.

Read more less

"The most elegant of all art critic cowboys” —Spike Art MagazineColor beams at us from the everyday, but within each of the ten million shades are hidden our best and worst stories. Colors is a collection of lush short stories about the many different shades that make up our lives. Berardini guides us through a spectrum of vignettes, weaving inspiration from Calvino’s Invisible Cities and Bowie’s Sound and Vision, arriving at color’s fundamental intersection with who we are and how we live.

Read more less

How did the Christian Right come to predominate in the Republican Party? Why, on the other hand, do secular and religiously liberal beliefs largely prevail in the Democratic Party? Our understanding of the rift between the Democratic and Republican parties-a rift in many ways fueled by religious beliefs-requires an analysis of the entire spectrum of religious and nonreligious players in the American political process and how their influence has evolved over a long period of time. Employing a sizeable collection of data on party members, activists, and elites, Geoffrey Layman examines the role of religion in the Democratic and Republican parties, and the ways in which religion has influenced the political process from the early 1960s through the late 1990s. Using a wide variety of sources, including the American National Election Studies-the major academic survey of the American electorate-Layman reveals a vast and subtly differentiated landscape of political life and a more vivid basis upon which to analyze the ever-widening chasm between the parties. Layman investigates a broad spectrum of religious variety, citing differences between African American Protestants, white evangelical Protestants, Roman Catholics, Jews, nonreligious or seculars, and smaller religious groups, as well as political cleavages within these faith traditions. With his broad-based and thorough analysis, he counters the often narrow focus and incendiary rhetoric of many of the "culture war" debates.

Read more less

Renal Cancer: Current Status and Innovations provides a useful guide to the fundamental basics and latest diagnostic and treatment techniques for Renal Cancer. It features clearly structured and easy-to-understand chapters enabling the reader to develop a thorough understanding of screening, surveillance, diagnostics, pathology, robotic and open surgical approaches, ablation, medical treatment, psychology, and future innovations. The book provides a valuable resource for the full spectrum of clinicians involved in the multidisciplinary management of Renal Cancer.

Read more less

Histologic Basis of Ocular Disease in Animals is a comprehensive reference covering pathology of the eye in a spectrum of animal species, including domestic animals, fish, birds, and laboratory animals. Offers a comprehensive resource on diseases and conditions of the eye and orbit in a wide range of species Covers domestic animals, fish, birds, and laboratory animals Presents more than 1200 high-quality images carefully selected to illustrate the ocular conditions covered Emphasizes unique pathological responses where necessary

Read more less