Search results for ""Author LEONARD""

Due to increased awareness of the AIDS crisis as well as concern about environmental chemicals, immunotoxicology has quickly become one of the most important and controversial topics in occupational medicine and toxicology. This insightful reference/text clarifies the subject by exploring the basic environmental, occupational, and therapeutic agents that can suppress or strengthen the immune system. The authors provide a necessary bridge between immunology and toxicology to explain the various products and processes that may change immune parameters, affect host resistance to infections and tumors, and alter a system's future reaction to exposure. They assess the damage done not only to the immune system, but also damage by the immune system as a result of altered functioning. Throughout the book, emphasis is placed on the relevance to existing clinical health and possible future adverse effects. Even the more common immunotoxic conditions, such as food and drug intolerance, cigarette smoking, and occupational asthma, are put into perspective, with straightforward information on possible genetic, environmental, and pharmacological risk factors. Detailed sections are included on: Organ systems and target cells most often affected Types of damage and injury resulting from immunotoxic reactions Clinical populations in which immune system damage occurs Methods for investigating the etiology of agents and risk assessment Relevance of laboratory data to human risk Strategies for achieving standard practices to prevent the disparity in results that characterizes many immune system studies Regulatory affairs related to immunotoxicology Laboratory and experimental findings are probed to determine how and to what degree different immunotoxicants have induced clinical disease. Citations of animal research are restricted to those studies that point the way for future human studies, or have direct relevance to human situations. To further the reader’s understanding of xenobiotics, the authors treat the subject of purposeful immunomodulation, achieved by administering immunosuppressive or immunopotentiating drugs. Despite increasing public awareness, there remains an inaccurate perception of what chemicals can and cannot do. This important reference sets the record straight, making it an essential source for toxicologists, immunologists, industrial hygienists, microbiologists, allergists, as well as all professionals in the agricultural and cosmetic industries, and those involved in chemical and biological regulation.

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For more than fifty years, students and teachers have made the two-volume resource Sources of Indian Traditions their top pick for an accessible yet thorough introduction to Indian and South Asian civilizations. Volume 2 contains an essential selection of primary readings on the social, intellectual, and religious history of India from the decline of Mughal rule in the eighteenth century to today. It details the advent of the East India Company, British colonization, the struggle for liberation, the partition of 1947, and the creation of Pakistan, Bangladesh, and contemporary India. This third edition now begins earlier than the first and second, featuring a new chapter on eighteenth-century intellectual and religious trends that set the stage for India's modern development. The editors have added material on Gandhi and his reception both nationally and abroad and include different perspectives on and approaches to Partition and its aftermath. They expand their portrait of post-1947 India and Pakistan and add perspectives on Bangladesh. The collection continues to be divided thematically, with a section devoted to the drafting of the Indian constitution, the rise of nationalism, the influence of Western thought, the conflict in Kashmir, nuclear proliferation, minority religions, secularism, and the role of the Indian political left. A phenomenal text, Sources of Indian Traditions is more indispensable than ever for courses in philosophy, religion, literature, and intellectual and cultural history.

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This Open Access book highlights the ethical issues and dilemmas that arise in the practice of public health. It is also a tool to support instruction, debate, and dialogue regarding public health ethics. Although the practice of public health has always included consideration of ethical issues, the field of public health ethics as a discipline is a relatively new and emerging area. There are few practical training resources for public health practitioners, especially resources which include discussion of realistic cases which are likely to arise in the practice of public health. This work discusses these issues on a case to case basis and helps create awareness and understanding of the ethics of public health care. The main audience for the casebook is public health practitioners, including front-line workers, field epidemiology trainers and trainees, managers, planners, and decision makers who have an interest in learning about how to integrate ethical analysis into their day to day public health practice. The casebook is also useful to schools of public health and public health students as well as to academic ethicists who can use the book to teach public health ethics and distinguish it from clinical and research ethics.

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The question of whether to tax income from wealth has sparked debate since our country’s inception. Does taxing capital income ensure the progressivity of our system or merely discourage saving? Would switching our tax code to one that taxes only consumption be more efficient or only burden middle- and low-income people? And if we were to radically reform the way America taxes its citizens, how could we ensure that vital revenue would not be lost? Some analysts would even argue that, under our present byzantine tax system, we don’t really tax capital income at all. In this volume, eminent economists analyze the problems associated with taxing capital income and propose policy solutions, which are then challenged by their peers in informed commentary. It may not settle the debate, but policymakers, scholars, and the public will find a wealth of information and ideas to consider.

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Practical guidance for wildlife professionals working to improve study design, data analysis, and the application of results to habitat and population management.Winner of the Wildlife Society Publications Book Award by The Wildlife SocietyDespite major advances in sampling techniques and analytical methods, many animal ecologists conduct research that is primarily relevant to a specific time and place. They also tend to focus more on the statistical analyses and nuances of modeling than actual study design. Arguing that studies of animal ecology should always begin with a focus on the behaviors and characteristics of individual organisms, including how they form into distinct biological populations, Applications for Advancing Animal Ecology takes a fresh and critical look at the field. Building from its companion volume, Foundations for Advancing Animal Ecology, this practical book presents readers with the principal methods used to observe animal behavior. Teaching them to assess resource abundance categories of species-environmental relationships models, it also explores• major aspects of measuring animal habitat: what to measure and how to measure it;• common sampling and estimation methods to assess population parameters;• when to measure and how to analyze data;• problems that will confront ecologists in the coming years—and how to gather information to adequately address them; and• how the experimental approach can be used to advance the science of animal ecology.Throughout the book, the authors stress the importance of speaking a common and well-defined language. Avoiding vague and misleading terminology, they assert, will help ecologists translate science into meaningful and lasting actions in the environment. Taking the perspective of the organism of interest in developing concepts and applications, the authors always keep the potentially biased human perspective in focus. They also provide a selection of suggested research projects, cautions, and caveats. A major advancement in understanding the factors underlying wildlife–habitat relationships, Applications for Advancing Animal Ecology will be an invaluable resource to natural resource management professionals and practitioners, including state and federal agencies, non-governmental organizations, and environmental consultants.

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An effective treatment to help those with addictionsVictims of drug addiction, chronic illness, and mental illness all too often are overwhelmed with the affliction called hopelessness. Oxford Houses succeed because their substance abuse treatment approach instills the most powerful medicine—hope for recovery. Rescued Lives: The Oxford House Approach to Substance Abuse provides a comprehensive thought-provoking look at just how the innovative Oxford House model inspires positive action on one of our country’s most serious problems—substance abuse. This powerful book presents the success stories of the people living in these community homes and explains just how it has worked for them.Rescued Lives: The Oxford House Approach to Substance Abuse gives an insightful review of Oxford House’s history and the development of the approach. Residents’ stories reveal the treatment process on the road to recovery, allowing readers to glimpse the path each individual must travel to gain entrance and assimilate into the House community. As the residents gain more control over themselves living substance free, the reader discovers the importance of relationships and reframing of self in the recovery process. This powerful book can provide hope to those individuals who feel they have lost themselves in alcohol, drugs, and mental illness. Foreword by substance abuse scholar Bill White.Topics in Rescued Lives: The Oxford House Approach to Substance Abuse include:• an overview of substance abuse in today’s society• a history of Oxford House to the present• substance abuse treatment approaches• the process of a resident’s entrance and assimilation• providing hope and living substance free• the nationwide expansion of Oxford Houses• recovery, and what it means to women, children, and families• criminal offenders in Oxford House• how the Oxford House model is constructed in order to help disenfranchised individuals from society• the nine Oxford House Traditions• a review of the strong evidence that Oxford House works—and why• and more!Rescued Lives: The Oxford House Approach to Substance Abuse is enlightening reading for educators and students of psychology, sociology, urban studies, education, and other courses designed to prepare students for careers in the helping professions. This book is also essential for practicing clinicians, anyone concerned with society’s problems and those impacted by substance abuse and mental illness.

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A comprehensive exploration of the effects of fires--in forests and other environments--on soils, watersheds, vegetation, air and cultural resources.

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A look at how wildlife professionals can modernize their approaches to habitat and population management with a fresh take on animal ecology.How can we maximize the probability that a species of wild animal will persist into the future? This audacious book proposes that advancing animal ecology—and conservation itself—demands that we reenvision our basic understanding of how animals interact with their environments and with each other. Synthesizing where we are and where we need to go with our studies of animals and their environs, Foundations for Advancing Animal Ecology asserts that studies of animal ecology should begin with a focus on the behaviors and characteristics of individual organisms. The book examines• the limitations of classic approaches to the study of animal ecology• how organisms organize into collections, such as breeding pairs, flocks, and herds• how the broader biotic and abiotic environment shapes animal populations, communities, and ecosystems• factors underlying the distribution and abundance of species through space and time• the links between habitat and population• why communication between researchers and managers is key• specific strategies for managing wild animal populations and habitats in an evolutionary and ecosystem contextThroughout, the authors stress the importance of speaking a common and well-defined language. Avoiding vague and misleading terminology, they argue, will help ecologists translate science into meaningful and lasting actions in the environment. Taking the perspective of the organism of interest in developing concepts and applications, the authors always keep the potentially biased human perspective in focus. A major advancement in understanding the factors underlying wildlife-habitat relationships, Foundations for Advancing Animal Ecology will be an invaluable resource to professionals and practitioners in natural resource management in public and private sectors, including state and federal agencies, non-governmental organizations, and environmental consultants.

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This volume provides the definitive treatment of fortune's formula or the Kelly capital growth criterion as it is often called. The strategy is to maximize long run wealth of the investor by maximizing the period by period expected utility of wealth with a logarithmic utility function. Mathematical theorems show that only the log utility function maximizes asymptotic long run wealth and minimizes the expected time to arbitrary large goals. In general, the strategy is risky in the short term but as the number of bets increase, the Kelly bettor's wealth tends to be much larger than those with essentially different strategies. So most of the time, the Kelly bettor will have much more wealth than these other bettors but the Kelly strategy can lead to considerable losses a small percent of the time. There are ways to reduce this risk at the cost of lower expected final wealth using fractional Kelly strategies that blend the Kelly suggested wager with cash. The various classic reprinted papers and the new ones written specifically for this volume cover various aspects of the theory and practice of dynamic investing. Good and bad properties are discussed, as are fixed-mix and volatility induced growth strategies. The relationships with utility theory and the use of these ideas by great investors are featured.

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This volume provides the definitive treatment of fortune's formula or the Kelly capital growth criterion as it is often called. The strategy is to maximize long run wealth of the investor by maximizing the period by period expected utility of wealth with a logarithmic utility function. Mathematical theorems show that only the log utility function maximizes asymptotic long run wealth and minimizes the expected time to arbitrary large goals. In general, the strategy is risky in the short term but as the number of bets increase, the Kelly bettor's wealth tends to be much larger than those with essentially different strategies. So most of the time, the Kelly bettor will have much more wealth than these other bettors but the Kelly strategy can lead to considerable losses a small percent of the time. There are ways to reduce this risk at the cost of lower expected final wealth using fractional Kelly strategies that blend the Kelly suggested wager with cash. The various classic reprinted papers and the new ones written specifically for this volume cover various aspects of the theory and practice of dynamic investing. Good and bad properties are discussed, as are fixed-mix and volatility induced growth strategies. The relationships with utility theory and the use of these ideas by great investors are featured.

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Ranging from macabre fantasies to fairy tales and tales of crime, these stories from the author of The Nutcracker create a rich fictional world. Hoffman paints a complex vision of humanity, where people struggle to establish identities in a hostile, absurd world.

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With complete, concise coverage of prevention, indications, diagnosis, and treatment, Pediatric Allergy, 4th Edition, is your go-to resource for current, clinically-focused content in the rapidly changing field of allergies and immune-mediated diseases in children. This highly regarded reference fully covers immunology and origins of allergy, growth and development, pregnancy, infancy, and early, middle, and late childhood-all with a new, practical, clinical focus. You'll find authoritative coverage of the full range of allergies in pediatric patients, from asthma and other common conditions to rare or uncommon allergies, providing a one-stop resource for clinicians across specialties who care for children. Focuses on the clinical application of science to the bedside, including clinical pearls discussing best practice approaches and guidelines. Integrates the latest research on the origins of allergy in early life, including pregnancy, the neonate, and infants. Includes new, evidence-based management guidelines for various diseases, including food allergy, atopic dermatitis, asthma and immunodeficiency. Provides new content on the prevention of allergies; asthma, eczema, and food allergies in young children; and extensive current guidelines and new therapies. Offers up-to-date information on key areas such as food challenges, skin testing, IgE diagnostic labs, immunotherapy, clinical immunology diagnostic testing, molecular diagnostics, and lung function testing. Highlights current guidance from a new team of leading experts with 150 anatomic schematics, clinical photos, and algorithms-many new to this edition. Covers gene therapy, stem-cell therapy, and a host of immunodeficiency diseases found in children with allergies. Discusses targeted biologics for severe allergic diseases, defects of innate immunity, rheumatic diseases of childhood, and inflammatory disorders. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

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