Search results for ""elsevier science""

The Atlas of Drosophila Morphology: Wild-type and Classical Mutants is the guide every Drosophila researcher wished they had when first learning genetic markers, and the tool they wish they had now as a handy reference in their lab research. Previously, scientists had only poor-quality images or sketches to work with, and then scattered resources online - but no single visual resource quickly at their fingertips when explaining markers to new members of the lab, or selecting flies to do their genetic crosses, or hybrids. This alphabetized guide to Drosophila genetic markers lays flat in the lab for easy referencing. It contains high-resolution images of flies and the appropriate marker on the left side of each page and helpful information for the marker on the facing page, such as symbol, gene name, synonyms, chromosome location, brief informative description of the morphology, and comments on marker reliability. A companion website with updated information, useful links, and additional data provided by the authors complements this extremely valuable resource.

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The previous two editions of the Human Nervous System have been the standard reference for the anatomy of the central and peripheral nervous system of the human. The work has attracted nearly 2,000 citations, demonstrating that it has a major influence in the field of neuroscience. The 3e is a complete and updated revision, with new chapters covering genes and anatomy, gene expression studies, and glia cells. The book continues to be an excellent companion to the Atlas of the Human Brain, and a common nomenclature throughout the book is enforced. Physiological data, functional concepts, and correlates to the neuroanatomy of the major model systems (rat and mouse) as well as brain function round out the new edition.

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As the autoimmune diseases could affect different organs, Translational Autoimmunity: Autoimmune Diseases in Different Organs addresses the spectrum of autoimmune diseases. The fourth volume of Translational Immunology Series focuses on clinical and laboratory details of autoimmune diseases which are broadly categorized into two types of organ-specific autoimmune diseases and non-organ specific autoimmune diseases (also known as systemic autoimmune diseases). Autoimmune rheumatic diseases such as systemic lupus erythematosus and rheumatoid arthritis, autoimmune rheumatic diseases such as diabetes mellitus and thyroid diseases, autoimmune neurologic diseases such as multiple sclerosis, as well as autoimmune hepatobiliary diseases, autoimmune renal diseases and autoimmune cutaneous diseases as the subject of discussion in Translational Autoimmunity: Autoimmune Diseases in Different Organs.

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The Practical Guide to Clinical Research and Publication provides a comprehensive overview of the key foundations of epidemiology, statistics and epidemiological studies. This book presents the most important terms and knowledge in the field from a medical point-of-view. Sections contain numerous, clinically-oriented examples and drawings to facilitate understanding and clarify the relation to clinic and practice. The book contains many graphics and key points for easier understanding and is written using bullet points for ease of use and comprehension. It is ideal for physicians and clinical researchers who want to use it as guidance for clinical research or teaching.

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Production of Biodiesel from Non-Edible Sources: Technological Updates offers a step-by-step guide to the production of biodiesel, providing comparisons of existing methods, new and state-of-the-art technologies, and real-world examples of implementation. The book discusses all potential non-edible feedstocks for biodiesel production, providing their properties, availability, and processing, including deeper insights into kinetic models and simulation of biodiesel fermentation. Readers will gain knowledge of existing parameters and methods for biodiesel production, optimization, scale-up, and sustainability, along with guidance on the practical implementation of these methods and techniques. Finally, environmental sustainability, techno-economic analysis, and policymaking aspects are considered and put into the context of future prospects. This book offers a step-by-step guide for researchers and industry practitioners involved in bioenergy, renewable energy, biofuels production and bioconversion processes.

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Cardiovascular and Respiratory Bioengineering focuses on computational tools and modeling techniques in cardiovascular and respiratory systems that help develop bioengineered solutions. The book demonstrates how these technologies can be utilized in order to tackle diseases and medical issues. It provides practical guidance on how a bioengineering or medical problem can be modeled, along with which computational models can be used. Topics include computer modeling of Purkinje fibers with different electrical potential applied, modeling of cardiomyopathies caused by sarcomeric gene mutations, altered sarcomere function, perturbations in intracellular ion homeostasis, impaired myocardial energetics at reduced costs, and more. The book also discusses blood flow through deformable blood vessels in human aorta, abdominal aortic aneurysm, carotid artery, coronary artery and plaque formation, along with content on stent deployment modeling and stent design and optimization techniques.

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Intensification of Sorption Processes: Active and Passive Mechanisms introduces a number of selected, advanced topics in sorption processes/process intensification, covering both theoretical and applicable aspects. The first part of the book is devoted to the study of sorption processes based on active mechanisms, including ultrasonic, microwave, high-gravity, electrical and magnetic fields, while the second part covers passive mechanisms like nanostructures and nanofluids, membrane, supercritical fluids and sorption processes based on geometry design and equipment structure. The focus of the book is on key aspects of novel process intensification technologies (processes and equipment), i.e., absorption and adsorption, working principles, and design and applications.

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Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases elucidates elaborately the role of caspase enzymes implicated in the initiation of molecular events leading to neuronal apoptosis in the neurodegenerative disease. The book starts with introduction to neuropathology, neurogenetics, and epidemiology of neurodegenerative disease and illustrates the involvement of human caspases, neuronal apoptosis, apoptotic pathways, genetic polymorphisms, and several other factors and underlying mechanisms in the pathology of Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease. An important focus in all chapters is the intricate mechanisms and interplay that occur during or leading to neuron death in neurodegenerative diseases, along with disease pathobiology.

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The gradual increase of population and the consequential rise in the energy demands in the recent years have led to the overwhelming use of fossil fuels. Hydrogen has recently gained substantial interest because of its outstanding features to be used as clean energy carrier and energy vector. Moreover, hydrogen appears to be an effective alternative to tackle the issues of energy security and greenhouse gas emissions given that it is widely recognized as a clean fuel with high energy capacity. Hydrogen can be produced by various techniques such as thermochemical, hydrothermal, electrochemical, electrolytic, biological and photocatalytic methods as well as hybrid systems. New Dimensions in Production and Utilization of Hydrogen emphasizes on the research, development and innovations in the production and utilization of hydrogen in the industrial biorefining, hydrotreating and hydrogenation technologies, fuel cells, aerospace sector, pharmaceuticals, metallurgy, as well as bio-oil upgrading. Moreover, the supply chain analysis, lifecycle assessment, techno-economic analysis, as well as strengths and threats of global hydrogen market are covered in the book. This book provides many significant insights and scientific findings of key technologies for hydrogen production, storage and emerging applications. The book serves as a reference material for chemical and biochemical engineers, mechanical engineers, physicists, chemists, biologists, biomedical scientists and scholars working in the field of sustainable energy and materials.

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Modeling and Control of Drug Delivery Systems provides comprehensive coverage of various drug delivery and targeting systems and their state-of-the-art related works, ranging from theory to real-world deployment and future perspectives. Various drug delivery and targeting systems have been developed to minimize drug degradation and adverse effect and increase drug bioavailability. Site-specific drug delivery may be either an active and/or passive process. Improving delivery techniques that minimize toxicity and increase efficacy offer significant potential benefits to patients and open up new markets for pharmaceutical companies. This book will attract many researchers working in DDS field as it provides an essential source of information for pharmaceutical scientists and pharmacologists working in academia as well as in the industry. In addition, it has useful information for pharmaceutical physicians and scientists in many disciplines involved in developing DDS, such as chemical engineering, biomedical engineering, protein engineering, gene therapy.

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Insomnia and fatigue are two of the most frequent consequences after traumatic brain injury (TBI). About 30% of individuals suffer from chronic insomnia, an additional 20% have symptoms of insomnia, and up to 75% have significant and persistent fatigue. There is a strong empirical basis for the effectiveness of cognitive-behavioral interventions for the management of insomnia and fatigue in the general population and in other patient populations, and emerging research shows that these interventions seem applicable with similar benefits to people with TBI. Insomnia and Fatigue After Traumatic Brain Injury: A CBT Approach to Assessment and Treatment is written by a team of four scientist-practitioners in psychology who are experts in sleep medicine, cognitive-behavioral therapy for insomnia, and traumatic brain injury (TBI). Together they have authored this assessment and intervention manual for insomnia and fatigue, intended for clinicians working with the TBI population. Based on cognitive-behavioral principles, the manual integrates evidence-based interventions and techniques used by expert clinicians working with these populations. Throughout the development process, there has been an ongoing integration of the best available research, specialized clinical expertise, and knowledge transfer expertise: all of these perspectives were used to choose, revise, and format the content of the manual as to ensure that it would be most useful for the target audience.

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Recent Trends in Swarm Intelligence Enabled Research for Engineering Applications focuses on recent, up-to-date technologies, combining other intelligent tools with swarm intelligence techniques to yield robust and failsafe solutions to real world problems. This book aims to provide audiences with a platform to learn and gain insights into the latest developments in hybrid swarm intelligence. It will be useful to researchers, engineers, developers, practitioners, and graduate students working in the major and interdisciplinary areas of computational intelligence, communication systems, computer networks, and soft computing. With the advent of data-intensive applications, the elimination of redundancy in disseminated information has become a serious challenge for researchers who are on the lookout for evolving metaheuristic algorithms which can explore and exploit the information feature space to derive the optimal settings for specific applications. Swarm intelligence algorithms have

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Bioremediation for Environmental Sustainability: Approaches to Tackle Pollution for Cleaner and Greener Society discusses many recently developed and successfully applied bio/phytoremediation technologies for pollution control and minimization, which are lacking more comprehensive coverage in previous books. This book describes the scope and applications of bio/phytoremediation technologies and especially focuses on the associated eco-environmental concerns, field studies, sustainability issues, and future prospects. The book also examines the feasibility of environmentally friendly and sustainable bio/phytoremediation technologies to remediate contaminated sites, as well as future directions in the field of bioremediation for environmental sustainability.

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Migraine Biology, Diagnosis, and Co-Morbidities, Volume 198 covers a wide range of issues related to migraine. The epidemiology, global, and personal impacts of migraine are covered, including topics on the pathophysiology of migraine and migraine aura, the pathophysiology of the associated symptoms of photophobia and phonophobia, and the genetics of migraine. The classification and diagnostic criteria of common and uncommon subtypes of migraine are also explored in detail, including childhood variants. Issues related to the diagnosis and management of vestibular migraine and the co-morbid disorder of persistent postural-perceptual dizziness are also covered. Finally, the important comorbidities of migraine such as anxiety, depression and other forms of chronic pain are discussed, along with the current state and future directions of migraine research and management.

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Marine Mammal Ecotoxicology: Impacts of Multiple Stressors on Population Health provides tactics on how to develop a comprehensive methodology for the study of existing threats to marine mammals. By presenting a conservation-biology approach and new and emerging technologies, this work helps provide crucial knowledge on the status of marine mammal populations that not only helps readers understand the ecosystem’s health, but also instigate mitigation measures. This volume provides information that helps investigators unravel the relationships between exposure to environmental stressors (e.g., climate change, pollutants, marine litter, pathogens and biotoxins) and a range of endpoints in marine mammal species. The application of robust examination procedures and biochemical, immunological, and molecular techniques, combined with pathological examination and feeding ecology, has led to the development of health assessment methods at the individual and population levels in wild marine mammals.

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Groundwater Science, Third Edition covers physical and chemical aspects of groundwater science, with emphasis on applications in the hydrologic cycle and in water supply, including contamination, mining, and construction issues. This interdisciplinary text weaves important methods and applications from the disciplines of physics, chemistry, mathematics, geology, biology, and environmental science, introducing the mathematical modeling of groundwater flow and contaminant transport. This fully updated edition includes all new case studies, expanded ancillary materials (including software), and expanded problems. The book is a valuable resource for students and instructors in the geosciences, environmental sciences, and civil engineering with a focus on hydrology and hydrogeology.

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Developmental Juvenile Osteology was created as a core reference text to document the development of the entire human skeleton from early embryonic life to adulthood. In the period since its first publication there has been a resurgence of interest in the developing skeleton, and the second edition of Developmental Juvenile Osteology incorporates much of the key literature that has been published in the intervening time. The main core of the text persists by describing each individual component of the human skeleton from its embryological origin through to its final adult form. This systematic approach has been shown to assist the processes of both identification and age estimation and acts as a core source for the basic understanding of normal human skeletal development. In addition to this core, new sections have been added where there have been significant advances in the field.

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Determination of Toxic Organic Chemicals in Natural Waters, Sediments and Soils: Determination and Analysis reviews the latest techniques for the determination and assessment of both current and emerging organic compounds in a range of important environmental contexts. A wide range of organic compounds in non-saline waters are discussed in the opening chapters, including hydrocarbons, surface active agents and volatile organic compounds. This is followed by multiorganics, pesticides and organometallic compounds in non-saline waters. Organic compounds in aqueous precipitation are then explored before the book goes on to discuss compounds in soils, including extraction techniques, insecticides, herbicides and fungicides, and organometallic compounds. Finally, the concluding chapters focus on compounds in sediments, providing readers with the latest information in the field and supporting them as they address the important issue surrounding organic material throughout ecosystems.

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Advances in Heat Transfer fills the information gap between regularly scheduled journals and university-level textbooks by providing in-depth review articles that are from a broader scope than in traditional journals or texts. The articles, which serve as a broad review for experts in the field, are also of great interest to non-specialists who need to keep up-to-date on the results of the latest research. This serial is essential reading for all mechanical, chemical, and industrial engineers working in the field of heat transfer, or in graduate schools or industry.

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Cellular and Molecular Pathobiology of Cardiovascular Disease focuses on the pathophysiology of common cardiovascular disease in the context of its underlying mechanisms and molecular biology. This book has been developed from the editors' experiences teaching an advanced cardiovascular pathology course for PhD trainees in the biomedical sciences, and trainees in cardiology, pathology, public health, and veterinary medicine. No other single text-reference combines clinical cardiology and cardiovascular pathology with enough molecular content for graduate students in both biomedical research and clinical departments. The text is complemented and supported by a rich variety of photomicrographs, diagrams of molecular relationships, and tables. It is uniquely useful to a wide audience of graduate students and post-doctoral fellows in areas from pathology to physiology, genetics, pharmacology, and more, as well as medical residents in pathology, laboratory medicine, internal medicine, cardiovascular surgery, and cardiology.

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HIV/AIDS continues to be the pandemic of our times and there has not been a comprehensive medically based AIDS prevention book published in the last 5 years. It is estimated that 36 to 45 million people including 2-3 million children already are infected worldwide and an additional 4-7 million more are infected each year. There are about 6,000 new infections daily and about 12 million AIDS orphans. People receiving AIDS treatments feel well and have no detectable viral load, but still can infect others. And even when a vaccine is found, it will take many years before it can be administered across the developing world.

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Circuits, Signals and Systems for Bioengineers: A MATLAB-Based Introduction, Third Edition, guides the reader through the electrical engineering principles that can be applied to biological systems. It details the basic engineering concepts that underlie biomedical systems, medical devices, biocontrol and biomedical signal analysis, providing a solid foundation for students in important bioengineering concepts. Fully revised and updated to better meet the needs of instructors and students, the third edition introduces and develops concepts through computational methods that allow students to explore operations, such as correlations, convolution, the Fourier transform and the transfer function. New chapters have been added on image analysis, noise, stochastic processes and ergodicity, and new medical examples and applications are included throughout the text.

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Threat and Violence Interventions: The Effective Application of Influence evaluates threat and violence risk for various levels of mental health practitioners, law enforcement officers, security professionals, human resource professionals, attorneys, and academics in forensic psychology, sociology, criminology and law. Currently, both empirical and practical literature has focused, to an almost exclusive extent, on the assessment of human behavior and propensity for violence. However, most cases of high concern for potential physical violence arise from individuals who have yet to act in ways the criminal justice system can address. This book broaches the topic, exploring tactics and providing practical, concrete suggestions.

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Haschek and Rousseaux's Handbook of Toxicologic Pathology, Fourth Edition, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive coverage. The fourth edition has been expanded to five separate volumes due to an explosion of information in this field requiring new and updated chapters. Completely revised with a number of new chapters, this book covers the toxicologic pathology of major classes of environmental toxicants. Volumes emphasize the comparative and correlative aspects of normal biology and toxicant-induced dysfunction, principal methods for toxicologic pathology evaluation, and major mechanisms of toxicity. This series comprises the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Each volume is being published separately.

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Neuropalliative Care, Part Two, Volume 191 covers a type of care that is given when there is no cure for the neurological disorder and the patient is in distress. It provides a scholarly background of neuropalliative care, from historic underpinnings to its practice in various geographical regions, along with best practices for specific neurological disorders. It covers the work of multi or interdisciplinary teams whose care is intended to make the patient as comfortable as possible and includes partners and families in treatment plans.

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Diagnosis and Treatment of Spinal Cord Injury will enhance readers’ understanding of the complexities of the diagnosis and management of spinal cord injuries. Featuring chapters on drug delivery, exercise, and rehabilitation, this volume discusses in detail the impact of the clinical features, diagnosis, management, and long-term prognosis of spinal cord injuries on the lives of those affected. The book has applicability for neuroscientists, neurologists, clinicians, and anyone working to better understand spinal cord injuries.

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Spinal injury affects about 10 million people annually worldwide, impacting on the family unit and causing lifelong disabilities, with varied symptoms including paresthesia, spasticity, loss of motor control, and often severe pain. Cellular, Molecular, Physiological, and Behavioral Aspects of Spinal Cord Injury will enhance readers’ understanding of the biological and psychological effects of spinal cord injury. Featuring chapters on gene expression, metabolic effects, and behavior, this volume discusses in detail the impact of spinal cord injury to better understand the underlying pathways and processes. The book has applicability for neuroscientists, neurologists, clinicians, and anyone working to better understand these injuries.

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Sabermetrics: Baseball, Steroids, and How the Game has Changed Over the Past Two Generations offers an introduction to this increasing area of interest to statisticians, students of the game, and many others. Pairing a primer on the applied math with an overview of the origin of the field and its context within baseball today, the work provides an engaging resource for students and interested readers. It includes coverage of relevant baseball history, Bill James and SABR, broken records and steroids. Drawing on the author’s experience teaching the subject at Seton Hall University since 1988, Sabermetrics also offers practice questions and solutions for class use.

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Chemical Fate and Transport in the Environment, Fourth Edition explains the fundamental principles of mass transport, chemical partitioning, and chemical/biological transformations of pollutants and naturally occurring chemicals in surface waters, in the subsurface (which includes soil and groundwater), and in the atmosphere. Each of these three major environmental media is introduced by a descriptive overview, followed by presentations of the governing physical, chemical, and biological processes. The text emphasizes intuitively based mathematical models for chemical equilibria, transformations, and transport in the environment. This book serves as a primary text for graduate and senior undergraduate courses in environmental science and engineering, provides relevant scientific knowledge for students of public health and environmental policy, and is a useful reference for environmental practitioners. This fourth edition builds on the third edition, which won a 2015 Textbook Excellence Award (Texty) from The Text and Academic Authors Association. This updated textbook expands the discussion of global climate change, presents concepts of stationarity and sustainability, provides additional coverage of wastewater treatment and air pollution abatement technologies, and includes information on additional anthropogenic pollutants such as plastics, PFAS, and nanoparticles. Tables, figures, and references are updated, and worked examples and practice exercises are included for each chapter.

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Nutraceuticals: Efficacy, Safety and Toxicity, Second Edition, brings together everything that is currently known about nutraceuticals and their potential toxic effects. The book introduces readers to nutraceuticals, herbal medicines, Ayurvedic medicines, prebiotics, probiotics, adaptogens, and their uses and specific applications. This essential reference discusses the mechanism of action for the judicious use of these nutraceuticals and the best tools for their evaluation before detailing the safety and toxicity of nutraceuticals and interactions with other therapeutic drugs. Finally, and crucially, regulatory aspects from around the world are covered. Completely revised and updated, this updated edition provides toxicologists, pharmacologists, pharmaceutical scientists, and those interested in medicinal plants and natural products with a comprehensive overview of the most effective tools upon which to evaluate the safety and toxicity of nutraceuticals, prebiotics, probiotics and alternative medicines.

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Discrete Mathematics: Essentials and Applications offers a comprehensive survey of the area, particularly concentrating on the basic principles and applications of Discrete Mathematics. This up-to-date text provides proofs of significance, keeping the focus on numerous relevant examples and many pertinent applications. Written in a simple and clear tone, the title features insightful descriptions and intuitive explanations of all complex concepts and ensures a thorough understanding of the subject matter.

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Vertebrate Endocrinology, Sixth Edition, provides a comprehensive, up-to-date treatment of the endocrine system for college and university students as well as researchers. This book is logically arranged, easily comprehended, and well-illustrated. It covers traditional hormone-based systems and introduces all forms of chemical communication, their implications for the health of humans, domesticated, and wild vertebrates. Written by two experts who have completed extensive research in comparative vertebrate endocrinology with an emphasis on natural and anthropogenic environmental factors influencing endocrine systems. Collectively, the authors have taught courses in endocrinology at the undergraduate and graduate level for more than 60 years. After first publishing in 1985, Vertebrate Endocrinology, Sixth Edition, continues to serve as an important resource for graduate students and advanced undergraduates in the biological sciences, animal sciences, and veterinary sciences. Endocrine researchers will also benefit from the book’s relevance in the areas of comparative, veterinary, and mammalian endocrinology.

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Exploring Monte Carlo Methods, Second Edition provides a valuable introduction to the numerical methods that have come to be known as "Monte Carlo." This unique and trusted resource for course use, as well as researcher reference, offers accessible coverage, clear explanations and helpful examples throughout. Building from the basics, the text also includes applications in a variety of fields, such as physics, nuclear engineering, finance and investment, medical modeling and prediction, archaeology, geology and transportation planning.

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Mergers, Acquisitions, and Other Restructuring Activities: An Integrated Approach to Process, Tools, Cases, and Solutions, Eleventh Edition presents the most current and comprehensive M&A information available. Organized according to the context in which topics normally occur in the M&A process, the book covers M&A environments, M&A processes, M&A valuation and modeling, deal structuring and financing strategies, and alternative business and restructuring strategies. Covering industries worldwide, this new edition illustrates the most germane strategies and tactics in today's marketplace. It includes substantially more ancillary materials than previous editions, including an extensive test bank, chapter summaries, and instructor and student PowerPoint slides. More than 100 new references to relevant academic research published since 2018 make the 11th edition a balanced, comprehensive guide to the complex and dynamically changing world of M&A.

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Features and Assessments of Pain, Anaesthesia and Analgesia examines the syndromes of pain and how they interlink with anesthesia and analgesics. The book covers assessments, screening and resources, and provides applications to related areas of medicine. It explores how the perception of pain results from a multifaceted interaction between illness beliefs, age, gender, time of onset, stress, socioeconomic status, and any number of other factors. In addition, the book scrutinizes how the neuroscience of pain in one condition may be relevant to understanding pain observed in other conditions.

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The complement to The Rat Brain in Stereotaxic Coordinates, Chemoarchitectonic Atlas of the Rat Brain, Third Edition, features a single brain series of high-quality plates stained with eight different markers, extensively annotated and labelled throughout. Plates from the previous edition of Chemoarchitectonic Atlas of the Rat Brain have been re-scanned at high resolution and are shown in color. Labeled structures have been revised, corrected, and updated, providing users with a streamlined, up-to-date, and highly accurate compendium of chemical markers. Researchers with a need to understand the detailed organization of the rat brain as well as structure/function relationships will need this atlas and its array of stains.

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