Description

The number of available synthetic methods can be overwhelming. In order to create novel motifs and templates which confer new and potentially valuable drug-like properties, it is important to know which synthetic methodologies will give the best results. This two-volume set of books provides both academic and industrial perspectives on key reactions giving the reader an excellent overview of the techniques used in modern synthesis. Reaction types are conveniently framed in the context of their value to industry and the challenges and limitations of methodologies are discussed with relevant illustrative examples. Moreover, key opportunities in expanding chemical space are presented, including the increasingly important syntheses that introduce three-dimensional molecular shape. Volume 1 focusses on transition metal mediated methods used in industry and volume 2 covers further valuable methods, such as fluorination, C-N bond formation and asymmetric reactions. Edited and authored by lead

Synthetic Methods in Drug Discovery Complete Set

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The number of available synthetic methods can be overwhelming. In order to create novel motifs and templates which confer new... Read more

    Publisher: Royal Society of Chemistry
    Publication Date: 1/1/2016
    ISBN13: 9781782627876, 978-1782627876
    ISBN10: 1782627871

    Non Fiction , Education

    Description

    The number of available synthetic methods can be overwhelming. In order to create novel motifs and templates which confer new and potentially valuable drug-like properties, it is important to know which synthetic methodologies will give the best results. This two-volume set of books provides both academic and industrial perspectives on key reactions giving the reader an excellent overview of the techniques used in modern synthesis. Reaction types are conveniently framed in the context of their value to industry and the challenges and limitations of methodologies are discussed with relevant illustrative examples. Moreover, key opportunities in expanding chemical space are presented, including the increasingly important syntheses that introduce three-dimensional molecular shape. Volume 1 focusses on transition metal mediated methods used in industry and volume 2 covers further valuable methods, such as fluorination, C-N bond formation and asymmetric reactions. Edited and authored by lead

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