Description
Book SynopsisHighlighting dynamic developments in polymer synthesis, this book focuses on the chemical techniques to synthesize and characterize biomedically relevant polymers and macromolecules.
Aids researchers developing polymers and materials for biomedical applications
Describes biopolymers from a synthetic perspective, which other similar books do not do
Covers areas that include: cationically-charged macromolecules, pseudo-peptides, polydrugs and prodrugs, controlled radical polymerization, self-assembly, polycondensates, and polymers for surface modification
Table of ContentsList of Contributors ix
Part I. Pseudo-Peptides, Polyamino acids and Polyoxazolines 1
Chapter 1 - Characterization of Polypeptides and Polypeptoides –Methods and Challenges 3
David Huesmann and Matthias Barz
Chapter 2- Poly(2-Oxazoline): The structurally Diverse Biocompatibilizing Polymer 31
Rodolphe Obeid
Chapter 3- Poly(2-oxazoline) Polymers – synthesis, characterization and Applications in Development of Therapeutics 51
Randall W. Moreadith and Tacey X. Viegas
Chapter 4- Polypeptoid Polymers: Synthesis, Characterization and Properties 77
Brandon A. Chan, Sunting Xuan, Ang Li, Jessica M. Simpson and Donghui Zhang
Part II - Advanced Polycondensates 121
Chapter 5 - Polyanhydrides: Synthesis and Characterization 123
Rohan Ghadi, Eameema Muntimadugu Wahid Khan and Abraham J. Domb
Chapter 6 - New Routes to Tailor-Made Polyesters 149
Kazuki Fukushima and Tomoko Fujiwara
Chapter 7 - Polyphosphoesters: An old biopolymer in a new light 191
Kristin N. Bauer, Hisaschi T.C. Tee, Evandro M. Alexandrino and Frederik R. Wurm
Part III. Cationically Charged Macromolecules 243
Chapter 8 - Design and Synthesis of Amphiphilic Vinyl Copolymers with Antimicrobial Activity 245
Leanna L. Foster, Masato Mizutani, Yukari Oda, Edmund F. Palermo and Kenichi Kuroda
Chapter 9 - Enhanced Polyethylenimine-Based Delivery of Nucleic Acids 273
Jeff Sparks, Tooba Anwer and Khursheed Anwer
Chapter 10 - Cationic graft copolymers for DNA engineering 297
Atsushi Maruyama and Naohiko Shimada
Part IV. Biorelated polymers by Controlled Radical Polymerization 313
Chapter 11 - Synthesis of (Bio)degradable Polymers by Controlled/“Living” Radical Polymerization 315
Shannon R. Woodruff and Nicolay V. Tsarevsky
Part V. Polydrugs and Polyprodrugs 355
Chapter 12 - Polymerized drugs – a novel approach to controlled release systems 357
B. Demirdirek, J. J. Faig, R. Guliyev and K.E.Uhrich
Chapter 13 - Structural design and synthesis of polymer prodrugs 391
Petr Chytil, Libor Kostka and Tomáš Etrych
Part VI. Biocompatibilization of Surfaces 421
Chapter 14 - Polymeric ultrathin films for surface modifications 423
Henning Menzel
Chapter 15 - Surface Functionalization of Biomaterials by Poly(2-oxazoline)s 457
Giulia Morgese and Edmondo M. Benetti
Chapter 16 - Biorelated polymer brushes by surface initiated reversible deactivation radical polymerization 487
Rueben Pfukwa, Lebohang Hlalele and Bert Klumperman
Part VII. Self-assembled Structures and Formulations 525
Chapter 17 - Synthesis of amphiphilic invertible polymers for biomedical applications 527
A.M. Kohut, I.O. Hevus, S.A. Voronov and A.S. Voronov
Chapter 18 - Bioadhesive Polymers for Drug Delivery 559
Eenko Larrañeta and Ryan F. Donnelly
INDEX
