Description
Book SynopsisAlthough normally thought of as a sex hormone, recent research has highlighted the numerous and significant effects that oestrogen has on the central nervous system. It has been shown that oestrogen acts as a neural growth factor with important influences on the survival, plasticity, regeneration, and aging of the mammalian forebrain.
Trade Review"The text is an excellent summary of what is new on estrogens in the brain and will be of interest to neuroscience departments..." --Jnl of the Neurological Sciences, March 2001
Table of ContentsChairman's Introduction (B. McEwen).
Mechanism of Oestrogen Signalling with Particular Reference to the Role of ERß in the Central Nervous System (E. Treuter, et al.).
Oestrogen Receptor Function at Classical and Alternative Response Elements (P. Kushner, et al.).
GENERAL DISCUSSION I.
Nuclear Receptor Versus Plasma Membrane Oestrogen Receptor (E. Levin).
Novel Sites and Mechanisms of Oestrogen Action in the Brain (C. Toran-Allerand).
Oestrogen Modulation of Noradrenaline Neurotransmission (A. Herbison, et al.).
Oestrogen and the Cholinergic Hypothesis: Implications for Oestrogen Replacement Therapy in Postmenopausal Women (R. Gibbs).
Ovarian Steroid Action in the Serotonin Neural System of Macaques (C. Bethea, et al.).
Oestrogen Effects on Dopaminergic Function in Striatum (J. Becker).
GENERAL DISCUSSION II.
Oestrogen Effects in Olivo-Cerebellar and Hippocampal Circuits (S. Smith, et al.).
Effects of Oestradiol on Hippocampal Circuitry (C. Woolley).
Oestrogen and Cognitive Function Throughout the Female Lifespan (B. Sherwin).
Neuroprotective Effects of Phenolic A Ring Oestrogens (P. Green, et al.).
The Female Sex Hormone Oestrogen as Neuroprotectant: Activities at Various Levels (C. Behl, et al.).
Neurohormonal Signalling Pathways and the Regulation of Alzheimer ß-Amyloid Metabolism (S. Gandy & S. Petanceska).
Oestrogens and Dementia (V. Henderson).
Indexes.
