Description
Book SynopsisNanotoxicology probing established paradigms using innovative approaches.- Use of sensors to provide real time assessment of cellular responses to nanomaterials in in vitro systems.- Recreating physi logical events using advanced in vitro models.- Emerging strategies for nanosafety assessment the power of multiplexing.- Genotoxicity and Epigenetics How nanomaterials interact with DNA and gene expression.- Section Two Bridging in vitro in vivo models Assessing nanomaterial hazard with lower tier organisms, reducing reliance on rodent models and ensuring sustainability in nanosafety approaches.- Caenorhabditis elegans as a model organism to probe nanosafety from morphological to molecular approach.- Drosophila melanogaster a dynamic in vivo model to study nano bio interactions.- Zebrafish embryos as a tool for nanomaterials hazard assessment.- Daphnia as a model organism in econanotoxicity assessment from individual to population effects.- Organ on a chip and nanosafety The latest in vitro platforms to predict hazard and streamline nanosafety assessment.- Skin on a chip.- Lung on a chip.- Gut on a chip.- Systems on a chip.- Computational approaches to nanosafety From traditional QSAR to Artificial Intelligence and Life Cycle Assessment.- Leveraging Opportunities for Computer Aided Nanosafety Integrating Nano QSTR with AI Generalized Read Across Models.- Advanced Structure Based Docking Protocols for Complex Nano Mixtures Risk Assessment.- Building Multiple Machine Learning Classifiers to Address Nanomaterial Risks Assessment.- Life Cycle Assessment a broader view of nanomaterials beyond biological effects.
