Description
Book SynopsisDespite the prevalence of both pharmaceutical and behavioral approaches to encourage cessation, over a billion people still indulge in tobacco. Even in the U.S., where tobacco use is considered a clearly treatable and socially regrettable condition, a significant percentage of individuals remain resistant to treatment modalities. It is believed that the problem lies with the availability, the effectiveness, and the tolerance of the treatments. Thus, the development of new and more effective medications for treating nicotine dependence is an area of significant therapeutic importance, and one made increasingly more viable given our rapidly increasing knowledge about the actions of nicotine and tobacco components on the brain.
We are entering a Renaissance period that promises to provide us with improved pharmacological tools to tackle this most serious of worldwide public health problems.
-- from the Preface
Medication Treatments for Nicotine Dependence assembl
Trade Review
“… this is a book that clinicians as well as researchers will find useful. … On the whole, individual chapters are well researched and presented, with a wealth of references to back up the prose. … This book provides an easy way for practitioners to avail themselves of the up-to-date research findings, which they may use in the treatment of nicotine additions. … This is certainly a book that will be useful to all who are doing research in the area of medication treatments for nicotine dependence, as well as for those who might be prescribing such medications. … it will also be valuable for those who are offering behavioral treatments and need to know how medications can be incorporated into their treatment plans. …”
—John C. Roitzsch, in PsycCritiques, Vol. 52, Release 30, Article 12, July 2007
". . . it can serve as an excellent reference to address questions about the mechanism of action or the pharmacologic rationale for a given therapy. The book is well-organized, so it will be useful as a reference."
– Meredith C. McCormack, Pulmonary and Critical Care Medicine, Johns Hopkins University, in Respiratory Care, September 2008, Vol. 53, No. 9
Table of ContentsPharmacological Effects of Nicotine and Nicotinic
Receptor Subtype Pharmacological Profiles. Cellular and Synaptic Effects of Nicotine. Animal Models of Nicotine Addiction.
Nicotine Replacement Therapies and Other Nicotinic Strategies. Sustained-Release Bupropion as a Pharmacological Aid to Smoking Cessation.Tricyclic Antidepressants in the Treatment of Nicotine Dependence.Monoamine Oxidase Inhibitors for Smoking Cessation.Opioid Antagonists for the Treatment of Nicotine Dependence. Other Nonapproved Agents for Smoking Cessation.Immunological Approaches to Nicotine Addiction. Glutamatergic Agents for Nicotine Dependence. GABAergic Agents for the Treatment of Nicotine Dependence.Cannabinoid Antagonists.Targeting the Dopamine D3 Receptor for
Treatment of Nicotine Dependence. Varenicline: An α4â2 Nicotinic Acetylcholine Receptor Partial Agonist as an Aid to Smoking Cessation.Combining Medications with Behavioral Treatments. Medication Treatments for Nicotine Dependence in Psychiatric and Substance Use Disorders. Pharmacogenetic Approaches to the Treatment of Nicotine Dependence. Neuroimaging of Nicotine Dependence.
Suggestions for Future Research. Treatment of Nicotine Dependence.
