Description

Book Synopsis
This book bridges the gap between advances in basic biology and chemistry and technological applications in the field of toxicity assessments. It describes areas of progress in the laboratory and clinic and discusses aspects of cellular organelles. It also covers the basic principles and applications of modern toxicological tools such as transcriptomic, proteomic, and metabolomic approaches. The recent developments on molecular modeling and systems biology are described with an eye on the future establishment of virtual cell technology. Finally the clinical implications for the understanding of acute and chronic renal toxicity are studied.

Table of Contents
Cellular Organelle-based Renal Toxicity. Transcriptomic Approaches. Proteomic Approaches. Metabolomic Approaches. Molecular Modeling – Molecular Design. Systems Biological Approaches. Virtual Cell. Clinical Implication of Renal Toxicology. Molecular Pathology of Renal Fibrosis. Classification of Nephrotoxicants.

Kidney

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    A Hardback by Sang Geon Kim

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      Book details

      Publisher CRC Press Inc
      Published 11 September 2013
      ISBN-13 9781466588110
      978-1466588110
      ISBN-10 146658811X
      Also in:
      Medical toxicology Biochemistry

      Description

      Book Synopsis
      This book bridges the gap between advances in basic biology and chemistry and technological applications in the field of toxicity assessments. It describes areas of progress in the laboratory and clinic and discusses aspects of cellular organelles. It also covers the basic principles and applications of modern toxicological tools such as transcriptomic, proteomic, and metabolomic approaches. The recent developments on molecular modeling and systems biology are described with an eye on the future establishment of virtual cell technology. Finally the clinical implications for the understanding of acute and chronic renal toxicity are studied.

      Table of Contents
      Cellular Organelle-based Renal Toxicity. Transcriptomic Approaches. Proteomic Approaches. Metabolomic Approaches. Molecular Modeling – Molecular Design. Systems Biological Approaches. Virtual Cell. Clinical Implication of Renal Toxicology. Molecular Pathology of Renal Fibrosis. Classification of Nephrotoxicants.

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