Description
Book SynopsisAs with the previous editions, Introduction to Toxicology, Fourth Edition, continues to chart the evolution of the field of toxicology, from the use of natural toxins by ancient tribes through the developments established by Paracelsus, and progresses through to the current topics in the public interest. For centuries, the study of toxicology has fascinated students. The book begins with basic toxicological principles, including an historical summary, dose-response relationships (NEW chapter), exposure-response relationships (NEW chapter), disposition, and metabolism of xenobiotic toxic substances. Other important new chapters include target organ toxicity, toxicity of carcinogenic agents and new and updated concepts in toxicity testing, and antidotes and treatment of poisonings. In all, nine new or expanded chapters from the third edition are advanced.
Current concerns about the effects of therapeutic drugs, carcinogens, industrial toxins, pesticides, and herbicides on
Table of Contents
1. Introduction. 2. Dose-Response Relationship. 3. Exposure-Response Relationship. 4. Disposition of Toxic Compounds. 5. Metabolism of Xenobiotic Compounds. 6. Target Organ Toxicity. 7. Carcinogenic and Mutagenic Compounds. 8. Drugs as Toxic Substances. 9. Industry Toxicology. 10. Food Additives and Contaminants. 11. Pesticides and Herbicides. 12. Environmental Pollutants. 13. Natural Products. 14. Commercial and Domestic Products. 15. Fundamentals of Toxicity Testing. 16. Risk Assessment. 17. Antidotes and Treatment of Poisoning. Answers to Chapter Questions. Glossary.
