Description
Book SynopsisThis book describes the processes that are involved in the development of new drugs. The authors discuss the history, role of natural products and concept of receptor interactions with regard to the initial stages of drug discovery. In a single, highly readable volume, it outlines the basics of pharmacological screening, drug target identification, and genetics involved in early drug discovery. The final chapters introduce readers to stem therapeutics, pharmacokinetics, pharmacovigilance, and toxicological testing.
Given its scope, the book will enable research scholars, professionals and young scientists to understand the key fundamentals of drug discovery, including stereochemistry, pharmacokinetics, clinical trials, statistics and toxicology.
Table of ContentsChapter 1: Historical Perspective of Drug Discovery and DevelopmentChapter2: Natural Products and Drug DiscoveryChapter 3: The Concept Of Receptors And Molecules Interaction In Drug Discovery And DevelopmentChapter 4: Chemical Structure and Stereochemistry Chapter 5:Biased Agonism:Renewing GPCR's targetabilityChapter 6: Computer Aided Drug DiscoveryChapter 7: Pharmacological screening of novel chemical entitiesChapter 8:Drug Target Identification and Validation:Chapter 9: Genetics and Drug DiscoveryChapter 10: Stem Cells and Therapeutics Chapter 11: Pharmacokinetics Chapter 12: Regulatory Toxicological TestingChapter 13: Nanotoxicology and Regulatory Requirements Chapter 14: Clinical Trials in Industrial Drug DevelopmentChapter 15:PharmacovigilanceChapter 16: Regulatory Process for New Drug Approval in IndiaChapter 17: Pharma Industry, Academia, Regulatory Authorities, and End-user Interaction in the Chapter 18: Statistics
