Description
Book SynopsisProvides coverage of the pathogenesis, clinical, morphologic, molecular and investigational aspects of a full range of blood disorders seen in daily practice
The revised fifth edition of this renowned atlas presents readers with a comprehensive, visual guide to clinical hematology, featuring 2700 full-color photographs and figures depicting the spectrum of hematological diseases. Ranging from photographs of the clinical manifestations and key microscopic findings to diagrams of the molecular aspects of these diseases, the book provides up-to-date information of the blood diseases that clinicians encounter every day.
Color Atlas of Clinical Hematology: Molecular and Cellular Basis of Disease offers the reader an understanding of normal cell machinery, and of the molecular basis for such processes as DNA and cell replication, RNA species, trafficking and splicing, protein synthesis, transcription factors, growth factor signal transduction, epigenetics, cell
Trade Review
"Substantially updated and now multi-authored so that all aspects of haematology are equally covered, including the newest developments in molecular biology and genomic sequencing. The latter is perhaps best realized in the first chapter ‘Molecular Biology of the Cell’, where the text and superb figures merge into a highly readable crash course in molecular biology.....I particularly enjoyed the chapter on myelodysplastic syndromes, where clonal heterogeneity is now did actically illustrated.....There is a surplus of invention in communicating complex problems here and an admirable effort to keep the reader totally up-to-date. Of note, there is now an eTextbook version of the Atlas.....Whenever there comes a new model of your smartphone, reviews always try to decide whether you should update from your old model. I would say that there is every reason to update your atlas, even if you have the second last edition. In conclusion, should you encounter one of the knowledge hungry students (be they of medical or master of science background) asking you whether haematology is an exciting career path to embark upon, one way to answer the question would be to hand her/him this atlas for half an hour. It is a major accomplishment and an excellent recruiting tool!"- Peter Hokland (British Journal of Haematology)
Table of Contents
Preface xxx
1 Molecular Biology of the Cell
2 Hematopoiesis
3 Growth Factor Signaling
4 Erythropoiesis and Examination of the Peripheral Blood and Bone Marrow
5 Hypochromic Anemias
6 The Porphyrias and Iron Overload
7 Megaloblastic Anemias
8 Hemolytic Anemias
9 Genetic Disorders of Hemoglobin
10 Benign Disorders of Phagocytes
11 Benign Disorders of Lymphocytes and Plasma Cells
12 Aplastic and Dyserythropoietic Anemias
13 The Hematologic Neoplasms: Laboratory Techniques and Acute Myeloid Leukemia
14 Acute Lymphoblastic Leukemia
15 Myelodysplastic Syndromes
16 Myeloproliferative Neoplasms
17 Mastocytosis, Myeloid/Lymphoid Neoplasms with Eosinophilia and Specific Cytogenetic Rearrangements, Myelodysplastic/Myeloproliferative Neoplasms
18 Chronic Lymphocytic Leukemia and Other Mature B- and T/Nk-Cell Leukemias
19 Small B-Cell Lymphomas
20 Aggressive Mature B-Cell Neoplasms
21 Myeloma and Related Neoplasms
22 Peripheral T- and NK-Cell Neoplasms
23 Hodgkin Lymphoma
24 Histiocytic Disorders
25 Stem Cell Transplantation
26 Normal Hemostasis, Platelet Production and Function
27 Vascular and Platelet Bleeding Disorders
28 Inherited and Acquired Coagulation Disorders
29 Thrombosis and Antithrombotic Therapy
30 Hematologic Aspects of Systemic Diseases
31 Parasitic Disorders
32 Blood Transfusion
Appendix 1 2016 World Health Organization Classification of Lymphoid and Myeloid Neoplasms
Index xxx
