Description
Book SynopsisThis book covers the discovery of molecular biomarkers, the development of laboratory testing techniques and their clinical applications, focusing on basic research to clinical practice. It introduces new and crucial knowledge and ethics of clinical molecular diagnosis. This book emphasizes the applications of clinical molecular diagnostic test on health management, especially from different diseased organs. It lets readers to understand and realize precision healthcare.
Table of ContentsPart I Principles of Clinical Molecular DiagnosticsChapter 1 Molecules of Diseases and Their Detection Methods
Chapter 2 Assay Performance Evaluation
Chapter 3 Establishment of Biological Reference Interval
Chapter 4 Ethics: Informed Consent, Patient Privacy
Chapter 5 Bioinformatics
Chapter 6 Report and Consultation
Chapter 7 Factors Associated with Variation
Chapter 8 Quality Control and Quality Assurance
Chapter 9 Precision Medicine
Part 2 Molecular Biomarkers and Signals from Diseased Functional Organ
Chapter 10 Molecules in Body Systems
Chapter 11 Molecules in Signal Pathways
Chapter 12 Endocrine and Metabolism
Chapter 13 Immune System
Chapter 14 Lipoproteins
Chapter 15 Transport and Carrier Proteins
Chapter 16 Coagulation and Fibrinolysis
Chapter 17 Cardiovascular System
Chapter 18 Pregnancy
Chapter 19 Urine
Chapter 20 Bone
Chapter 21 Cancer
Chapter 22 Translation Research of Novel Biomarker
Part 3 Advanced Molecular Diagnostic Techniques
Chapter 23 Next-generation Sequencing (NGS)
Chapter 24 Digital PCR
Chapter 25 Biosensor
Chapter 26 Microfluidic Chip
Chapter 27 Liquid Biopsy
Chapter 28 Molecular Targeted Imaging
Chapter 29 Fluorescence in Situ Hybridization
Chapter 30 Circulating DNA Quantification
Chapter 31 DNA Methylation Detection Techniques
Part 4 Disease Presentation and Clinical Laboratory Procedures
Chapter 32 Immunological Disorders
Chapter 33 Liver Diseases
Chapter 34 Pancreatic Diseases
Chapter 35 Digestive Tract Disease
Chapter 36 Kidney Diseases
Chapter 37 Cardiovascular Disease
Chapter 38 Lung Disease
Chapter 39 Blood Disorders
Chapter 40 Endocrine and Metabolic Diseases
Chapter 41 Neurological Disease
Chapter 42 Reproductive Organ Cancer
Chapter 43 Reproductive Organ Cancer
Chapter 44 Transplant Matching
Chapter 45 Paternity Test
